ABSTRACT There is a new argument form within theoretical biology. This form takes as input competing explanatory models; it yields as output the conclusion that one of these models is more plausible than the others. The driving force for this argument form is an analysis showing that one model exhibits more parametric robustness than its competitors. This article examines these inferences to the more robust explanation, analysing them as variants of inference to the best explanation. The article defines parametric robustness (...) and distinguishes it from more familiar kinds of robustness. The article also argues that parametric robustness is an explanatory virtue not subsumed by more familiar explanatory virtues, and that the plausibility verdicts in the conclusions of inferences to the more robust explanations are best interpreted as guidance for research activity, rather than claims about likely truth. 1Introducing Inference to the More Robust Explanation 2Inference to the More Robust Explanation in the Study of Apoptosis 2.1Regulating apoptosis 2.2Competing models and evidential indecision 2.3Measuring robustness 2.4Robustness as a guide to plausibility 2.5Varieties of robustness 3Inference to the More Robust Explanation as Inference to the Best Explanation 3.1The structure of inference to the best explanation 3.2Parametric robustness as an explanatory virtue rather than an explanandum 3.3Relation of parametric robustness to other explanatory virtues 4Epistemological Significance of Inference to the More Robust Explanation 4.1Plausibility in practice 4.2Plausibility in principle 5Conclusion. (shrink)

Explanationist accounts of rational legal proof view trials as a competition between explanations. Such accounts are often criticized for being underdeveloped. One question in need of further attention is when guilt is proven beyond a reasonable doubt in criminal trials. This article defends an inference to the best explanation -based approach on which guilt is only established BARD if the best guilt explanation in a case is substantially more plausible than any innocence explanation, and there is no good reason to (...) presume that we have overlooked evidence or alternative explanations that could realistically have exonerated the defendant. This is a comparative account, which I argue is better suited for arriving at accurate verdicts than the non-comparative ‘no plausible alternative’ account that many explanationists tacitly assume. Furthermore, this account is not susceptible to the most important arguments against IBE in criminal trials or to arguments against other, non-explanationist interpretations of the BARD standard. I use a case study to illustrate how this account provides meaningful guidance for decision makers in criminal trials. (shrink)

Eyewitness testimony is both an important and a notoriously unreliable type of criminal evidence. How should investigators, lawyers and decision-makers evaluate eyewitness reliability? In this article, I argue that Testimonial Inference to the Best Explanation is a promising, but underdeveloped prescriptive account of eyewitness evaluation. On this account, we assess the reliability of eyewitnesses by comparing different explanations of how their testimony came about. This account is compatible with, and complementary to both the Bayesian framework of rational eyewitness evaluation and (...) with prescriptive methods for eyewitness assessment developed by psychologists. Compared to these frameworks, the distinctive value of thinking in terms of competing explanations is that it helps us select, interpret and draw conclusions from the available evidence about the witness’s reliability. (shrink)

El presente artículo examina los argumentos aristotélicos en favor de la teleología para poner de manifiesto su estructura argumentativa que, a juicio del autor, es una inferencia a la mejor explicación. Finalmente se intenta relacionar la estrategia aristotélica con el tratamiento actual que se ha hecho de la finalidad desde la Filosofía de la Ciencia.

This paper takes as its point of departure two striking incongruities between scientiªc practice and trends in modern history and philosophy of science. (1) Many modern historians of science are so preoccupied with local scientiªc practices that they fail to recognize important non-local elements. (2) Many modern philosophers of science make a sharp distinction between explanation and evidence, whereas in scientiªc practice explanatory power is routinely used as evidence for scientiªc claims. I draw attention to one speciªc way in..

A central problem facing a probabilistic approach to the problem of induction is the difficulty of sufficiently constraining prior probabilities so as to yield the conclusion that induction is cogent. The Principle of Indifference, according to which alternatives are equiprobable when one has no grounds for preferring one over another, represents one way of addressing this problem; however, the Principle faces the well-known problem that multiple interpretations of it are possible, leading to incompatible conclusions. I propose a partial solution to (...) the latter problem, drawing on the notion of explanatory priority. The resulting synthesis of Bayesian and inference-to-best-explanation approaches affords a principled defense of prior probability distributions that support induction. (shrink)

This article examines what realists and anti-realist debates are all about. Through presenting the core of the main arguments in these debates, these are significant arguments and they are the kind of arguments that can clarify what it meant by ‘truth’ between Realist and anti-realist in general. The concluding remark is that though the main anti- realist’s arguments in these debates can be seen as some powerful arguments through raising questions on the relationship between theory and evidence, success and truth. (...) However, the success of science and the use of science in everyday life has not been given any satisfactory explanations by the anti-realists nor the use of it has been shut out from the daily life by these arguments against it. (shrink)

It is widely believed that many of the competing accounts of scientific explanation have ramifications which are relevant to the scientific realism debate. I claim that the two issues are orthogonal. For definiteness, I consider Cartwright's argument that causal explanations secure belief in theoretical entities. In Section I, van Fraassen's anti-realism is reviewed; I argue that this anti-realism is, prima facie, consistent with a causal account of explanation. Section II reviews Cartwright's arguments. In Section III, it is argued that causal (...) explanations do not license the sort of inferences to theoretical entities that would embarass the anti-realist. Section IV examines the epistemic commitments involved in accepting a causal explanation. Section V presents my conclusions: contra Cartwright, the anti-realist may incorporate a causal account of explanation into his vision of science in an entirely natural way. (shrink)

Nelson Goodman cast the ‘problem of induction’ as the task of articulating the principles and standards by which to distinguish valid from invalid inductive inferences. This paper explores some logical bounds on the ability of a rational reasoner to accomplish this task. By a simple argument, either an inductive inference method cannot admit its own fallibility, or there exists some non-inferable hypothesis whose non-inferability the method cannot infer (violating the principle of ‘negative introspection’). The paper discusses some implications of this (...) limited self-knowledge for the justifiability of inductive inferences, auto-epistemic logic, and the epistemic foundations of game theory. (shrink)

Machine learning systems have shown great potential for performing or supporting inferential reasoning through analyzing large data sets, thereby potentially facilitating more informed decision-making. However, a hindrance to such use of ML systems is that the predictive models created through ML are often complex, opaque, and poorly understood, even if the programs “learning” the models are simple, transparent, and well understood. ML models become difficult to trust, since lay-people, specialists, and even researchers have difficulties gauging the reasonableness, correctness, and reliability (...) of the inferences performed. In this article, we argue that bridging this gap in the understanding of ML models and their reasonableness requires a focus on developing an improved methodology for their creation. This process has been likened to “alchemy” and criticized for involving a large degree of “black art,” owing to its reliance on poorly understood “best practices”. We soften this critique and argue that the seeming arbitrariness often is the result of a lack of explicit hypothesizing stemming from an empiricist and myopic focus on optimizing for predictive performance rather than from an occult or mystical process. We present some of the problems resulting from the excessive focus on optimizing generalization performance at the cost of hypothesizing about the selection of data and biases. We suggest embedding ML in a general logic of scientific discovery similar to the one presented by Charles Sanders Peirce, and present a recontextualized version of Peirce’s scientific hypothesis adjusted to ML. (shrink)

The main factor of intelligence is defined as the ability tocomprehend, formalising this ability with the help of new constructsbased on descriptional complexity. The result is a comprehension test,or C- test, which is exclusively defined in computational terms. Due toits absolute and non-anthropomorphic character, it is equally applicableto both humans and non-humans. Moreover, it correlates with classicalpsychometric tests, thus establishing the first firm connection betweeninformation theoretical notions and traditional IQ tests. The TuringTest is compared with the C- test and the (...) combination of the two isquestioned. In consequence, the idea of using the Turing Test as apractical test of intelligence should be surpassed, and substituted bycomputational and factorial tests of different cognitive abilities, amuch more useful approach for artificial intelligence progress and formany other intriguing questions that present themselves beyond theTuring Test. (shrink)

This paper defines in a formal and computational way the notion of ‘consilience’, a term introduced by Whewell in 1847 for the evaluation of scientific theories. Informally, as has been used to date, a model or theory is ‘consilient’ if it is predictive, explanatory and unifies the evide-nce. Centred in a constructive framework, where new terms can be intro-duced, we essay a formalisation of the idea of unification based on the avoidance of ‘sepa-ration’. However, it is soon manifest that this (...) classical approach is vulnerable to the introduction of fantastic concepts to unify disparate sub-theories. Our second approach is constructed by using a detailed evaluation of the relationship between the theory and the evid-ence by means of reinforcement propagation. With the use of reinfor-cement, fantastic concepts can be better detected and the role of con-silience for theory construction and revision can be specialised for dif-ferent inference mechanisms like explanatory induction, abduction, deduc-tion and analogy. (shrink)

Two of the most influential theories about scientific inference are inference to the best explanation and Bayesianism. How are they related? Bas van Fraassen has claimed that IBE and Bayesianism are incompatible rival theories, as any probabilistic version of IBE would violate Bayesian conditionalization. In response, several authors have defended the view that IBE is compatible with Bayesian updating. They claim that the explanatory considerations in IBE are taken into account by the Bayesian because the Bayesian either does or should (...) make use of them in assigning probabilities to hypotheses. I argue that van Fraassen has not succeeded in establishing that IBE and Bayesianism are incompatible, but that the existing compatibilist response is also not satisfactory. I suggest that a more promising approach to the problem is to investigate whether explanatory considerations are taken into account by a Bayesian who assigns priors and likelihoods on his or her own terms. In this case, IBE would emerge from the Bayesian account, rather than being used to constrain priors and likelihoods. I provide a detailed discussion of the case of how the Copernican and Ptolemaic theories explain retrograde motion, and suggest that one of the key explanatory considerations is the extent to which the explanation a theory provides depends on its core elements rather than on auxiliary hypotheses. I then suggest that this type of consideration is reflected in the Bayesian likelihood, given priors that a Bayesian might be inclined to adopt even without explicit guidance by IBE. The aim is to show that IBE and Bayesianism may be compatible, not because they can be amalgamated, but rather because they capture substantially similar epistemic considerations. 1 Introduction2 Preliminaries3 Inference to the Best Explanation4 Bayesianism5 The Incompatibilist View : Inference to the Best Explanation Contradicts Bayesianism5. 1 Criticism of the incompatibilist view6 Constraint - Based Compatibilism6. 1 Criticism of constraint - based compatibilism7 Emergent Compatibilism7. 1 Analysis of inference to the best explanation7. 1. 1 Inference to the best explanation on specific hypotheses7. 1. 2 Inference to the best explanation on general theories7. 1. 3 Copernicus versus Ptolemy7. 1. 4 Explanatory virtues7. 1. 5 Summary7. 2 Bayesian account8 Conclusion. (shrink)

Objectivism about evidential support is the thesis that facts about the degree to which a body of evidence supports a hypothesis are objective rather than depending on subjective factors like one’s own language or epistemic values. Objectivism about evidential support is key to defending a synchronic, time-slice-centric conception of epistemic rationality, on which what you ought to believe at a time depends only on what evidence you have at that time, and not on how you were at previous times. Here, (...) I defend a version of objectivism about evidential support on which facts about evidential support are grounded in facts about explanatoriness. (shrink)

Marušić & Schwenkler (Analytic Philosophy, 59, 309) offer a simple and elegant defense of strong cognitivism about intention: the view that an intention to φ is a form of belief that one will φ. I show that their defense fails: however simple and elegant, it fails to account for various aspects about intention and its expression, and faces distinctive challenges of its own, including a dilemma and counterexample. These also undermine Marušić & Schwenkler's claim to a best-explanation type of account (...) and recommend alternatives to strong cognitivism altogether. (shrink)

This article argues, against contemporary experimentalist criticism, that conceptual analysis has epistemic value, with a structure that encourages the development of interesting hypotheses which are of the right form to be valuable in diverse areas of philosophy. The article shows, by analysis of the Gettier programme, that conceptual analysis shares the proofs and refutations form Lakatos identified in mathematics. Upon discovery of a counterexample, this structure aids the search for a replacement hypothesis. The search is guided by heuristics. The heuristics (...) of conceptual analysis are similar to those in other interesting areas of scholarship, and so hypotheses generated by it are of the right form to be applicable to diverse areas. The article shows that the explanationist criterion in epistemology was developed and applied in this way. The epistemic value of conceptual analysis is oblique because it contributes not towards the main purpose of conceptual analysis but towards the reliable development of epistemically valuable hypotheses in philosophy and scholarship. (shrink)

We can safely infer that a proposition is possible if p is the case. But, I argue, this inference from the actual to the possible is merely explicative in nature, though we employ it at times as if it were ampliative. To make this inference ampliative, we need to include an inference to the best explanation. Specifically, we can draw a substantive conclusion as to whether p is possible from the fact that p is the case, if via our best (...) explanation we can explain how p could occur again in the complete and coherent set of propositions that describes the actual world. (shrink)

David Chalmers supports his contention that there is a possible world populated by our zombie twins by arguing for the assumption that conceivability entails possibility. But, I argue, the modal epistemology he sets forth, ‘modal rationalism,’ ignores the problem of incompleteness and relies on an idealized notion of conceivability. As a consequence, this epistemology can’t justify our quotidian judgments of possibility, let alone those judgments that concern the mind/body connection. Working from the analogy that the imagination is to the possible (...) as perception is to the actual, I set forth a competing epistemology, ‘modal empiricism.’ This epistemology survives the incompleteness objection and allows some of our everyday modal judgments to be justified. But this epistemology can’t justify the claim that Zombie World is possible, which leaves Chalmers’s property dualism without the support it needs. (shrink)

We examine in detail three classic reasoning fallacies, that is, supposedly ``incorrect'' forms of argument. These are the so-called argumentam ad ignorantiam, the circular argument or petitio principii, and the slippery slope argument. In each case, the argument type is shown to match structurally arguments which are widely accepted. This suggests that it is not the form of the arguments as such that is problematic but rather something about the content of those examples with which they are typically justified. This (...) leads to a Bayesian reanalysis of these classic argument forms and a reformulation of the conditions under which they do or do not constitute legitimate forms of argumentation. (shrink)

In this article, we argue for the general importance of normative theories of argument strength. We also provide some evidence based on our recent work on the fallacies as to why Bayesian probability might, in fact, be able to supply such an account. In the remainder of the article we discuss the general characteristics that make a specifically Bayesian approach desirable, and critically evaluate putative flaws of Bayesian probability that have been raised in the argumentation literature.

My Representing and Intervening (1983) concludes with what it calls an experimental argument for scientific realism about entities. The argument is evidently inapplicable to extragalactic astrophysics, but leaves open the possibility that there might be other grounds for scientific realism in that domain. Here I argue for antirealism in astrophysics, although not for any particular kind of antirealism. The argument is conducted by a detailed examination of some current research. It parallels the last chapter of (1983). Both represent the methodological (...) opinion that abstract or semantic realism/antirealism debates are empty, and typically lead to confused or wrong conclusions because they pay so little attention to the details of a science. (shrink)

Agustín Rayo’s The Construction of Logical Space offers an exciting and ambitious defense of a broadly Carnapian approach to metaphysics. This essay will focus on one of the main differences between Rayo’s and Carnap’s approaches. Carnap distinguished between analytic, a priori “meaning postulates”, and empirical claims, which were both synthetic and knowable only a posteriori. Like meaning postulates, they determine the boundaries of logical space. But Rayo is skeptical that the a priori/a posteriori or analytic/synthetic distinctions can do the work (...) Carnap wanted them to, so unlike meaning postulates, ‘just is’-statements aren’t assumed to be analytic or knowable a priori. This essay will concern the epistemology of ‘just is’-statements in Rayo’s picture. If not by a priori reflection, how can we determine which ones to accept? I’ll distinguish two competing strands in Rayo’s work. The less radical, Lewisian strand holds that the question of whether to accept a ‘just is’-statement can be addressed in a neutral, non-question-begging way, by a kind of cost-benefit analysis. The more radical, Kuhnian strand holds that there can be no ‘just is’-statement-independent, rational choice of which ‘just is’-statements to accept. I argue that Rayo faces strong internal pressure to adopt the Kuhnian picture. While it is possible for Rayo to resist these Kuhnian pressures, natural strategies for doing so leave his view more similar to Carnap’s than the above gloss suggested. (shrink)

This paper states three counterexamples to the claim that testimony cannot generate knowledge, that a hearer can only acquire testimonial knowledge from a speaker who knows: a twins case, the fossil case, and an inversion case. The paper provides an explanation for why testimony can generate knowledge. Testimonial knowledge involves the flow of information from a speaker to a hearer through the linguistic channel.

Various proposals have suggested that an adequate explanatory theory should reduce the number or the cardinality of the set of logically independent claims that need be accepted in order to entail a body of data. A (and perhaps the only) well-formed proposal of this kind is William Kneale’s: an explanatory theory should be finitely axiomatizable but it’s set of logical consequences in the data language should not be finitely axiomatizable. Craig and Vaught showed that Kneale theories (almost) always exist for (...) any recursively enumerable but not finitely axiomatizable set of data sentences in a first order language with identity. Kneale’s criterion underdetermines explanation even given all possible data in the data language; gratuitous axioms may be “tacked on.” Define a Kneale theory, T, to be logically minimal if it is deducible from every Kneale theory (in the vocabulary of T) that entails the same statements in the data language as does T. If they exist, minimal Kneale theories are candidates for best explanations: they are “bold” in a sense close to Popper’s; some minimal Kneale theory is true if any Kneale theory is true; the minimal Kneale theory that is data equivalent to any given Kneale theory is unique; and no Kneale theory is more probable than some minimal Kneale theory. I show that under the Craig-Vaught conditions, no minimal Kneale theories exist. (shrink)

This paper considers an application of work on probabilistic measures of coherence to inference to the best explanation. Rather than considering information reported from different sources, as is usually the case when discussing coherence measures, the approach adopted here is to use a coherence measure to rank competing explanations in terms of their coherence with a piece of evidence. By adopting such an approach IBE can be made more precise and so a major objection to this mode of reasoning can (...) be addressed. Advantages of the coherence - based approach are pointed out by comparing it with several other ways to characterize ‘ best explanation ’ and showing that it takes into account their insights while overcoming some of their problems. The consequences of adopting this approach for IBE are discussed in the context of recent discussions about the relationship between IBE and Bayesianism. (shrink)

The running debate between Peter Achinstein and his critics concerning the nature of scientific evidence is misguided as each side attempts to explicate a distinct notion of evidence. Achinstein's approach, however, is valuable in helping to point out a problem with Carnap's statistical relevance model. By claiming an increase in probability to be necessary for evidence, the received view is incapable of accounting for evidence which is statistically irrelevant but explanatorily relevant. A broader view of evidence which can account for (...) pragmatic concerns such as explanation is thereby required. (shrink)

In his work on the epistemology of testimony, Peter Lipton developed an account of testimonial inference that aimed at descriptive adequacy as well as justificatory sophistication. According to ‘testimonial inference to the best explanation’, we accept what a speaker tells us because the truth of her claim figures in the best explanation of the fact that she made it. In this paper, I argue for a modification of this picture. In particular, I argue that IBE plays a dual role in (...) the management and justification of testimony. On the one hand, the coherence and success of our testimony-based projects provides general abductive support for a default stance of testimonial acceptance; on the other hand, we are justified in rejecting specific testimonial claims whenever the best explanation of the instances of testimony we encounter entails, or makes probable, the falsity or unreliability of the testimony in question.Keywords: Testimony; Inference to the best explanation; Abduction; Epistemic justification. (shrink)

This paper addresses the question of how scientists determine which type of hypothesis is most suitable for tackling a particular problem by examining the historical case of the anomalous β spectrum in early nuclear physics, a puzzle that occasioned the most diverse hypotheses amongst physicists at the time. It is shown that such determinations are most often implicitly informed by scientists' individual perspectives on the structural relations between the various elements of the theory and the problem at hand. In addition (...) to this main result, it is suggested that Wolfgang Pauli's neutrino idea may well have been an adaptation of Ernst Rutherford's original and older neutron idea, which would provide evidence that the adaptation of older ideas is a more common practice than is often thought. (shrink)

_Abduction of generalizations_ is the process in which explanatory hypotheses are formed for an observed, yet puzzling generalization such as ``pineapples taste sweet" or ``rainbows appear when the sun breaks through the rain". This phenomenon has received little attention in formal logic and philosophy of science. The current paper remedies this lacuna by first giving an overview of some general characteristics of this process, elaborating on its ubiquity in scientific and daily life reasoning. Second, the adaptive logic $\LAG$ is presented (...) to explicate this process formally. (shrink)

The Minimum Description Length principle is the modernformalisation of Occam's razor. It has been extensively and successfullyused in machine learning, especially for noisy and long sources ofdata. However, the MDL principle presents some paradoxes andinconveniences. After discussing all these, we address two of the mostrelevant: lack of explanation and lack of creativity. We present newalternatives to address these problems. The first one, intensionalcomplexity, avoids extensional parts in a description, so distributingcompression ratio in a more even way than the MDL principle. (...) The secondone, information gain, forces that the hypothesis is informative wrt. the evidence, so giving a formaldefinition of what is to discover. (shrink)

In this paper I want to cast doubt on the claim that there is a legitimate process of reasoning to the best explanation which can serve as an alternative to either straightforward inductive reasoning or a combination of inductive and deductive reasoning. I shall argue a) that paradigmatic cases of acceptable arguments to the best explanation must be considered enthymemes and b) that when the suppressed premises are made explicit we have all of the premises we need to present either (...) a straightforward inductive argument or an argument employing both induction and deduction. (shrink)

Do accounts of scientific theory formation and revision have implications for theories of everyday cognition? We maintain that failing to distinguish between importantly different types of theories of scientific inference has led to fundamental misunderstandings of the relationship between science and everyday cognition. In this article, we focus on one influential manifestation of this phenomenon which is found in Fodor's well-known critique of theories of cognitive architecture. We argue that in developing his critique, Fodor confounds a variety of distinct claims (...) about the holistic nature of scientific inference. Having done so, we outline more promising relations that hold between theories of scientific inference and ordinary cognition. (shrink)

Two long-standing arguments in cognitive science invoke the assumption that holistic inference is computationally infeasible. The first is Fodor’s skeptical argument toward computational modeling of ordinary inductive reasoning. The second advocates modular computational mechanisms of the kind posited by Cosmides, Tooby and Sperber. Based on advances in machine learning related to Bayes nets, as well as investigations into the structure of scientific and ordinary information, I maintain neither argument establishes its architectural conclusion. Similar considerations also undermine Fodor’s decades-long diagnosis of (...) artificial intelligence research as confounded by an inability to circumscribe the amount of information relevant to inferential processes. This diagnosis is particularly inapposite with respect to Bayes nets, since one of their strengths as machine learning systems has been their capacity to reason probabilistically about large data sets whose size overwhelms the capacities of individual human reasoners. A general moral follows from these criticisms: Insights into artificial and human cognitive systems are likely to be cultivated by focusing greater attention on the structure and density of connections among items of information that are available to them. (shrink)

Primeiramente, oferecemos uma apresentação teórica da representação do pensamento prático, começando pela distinção entre silogismo dialético e silogismo demonstrativo. Fazemos referência à crítica de Toulmin contra o dedutivismo dominante de seu tempo. Em seguida, fornecemos argumentos para apoiar a relevância heurística do modelo de Toulmin para entender a discussão sobre a inclusão da lógica padrão na representação do pensamento comum. Afirmamos que o projeto analítico toulmaniano permite entender, com clareza metódica, a derrotabilidade dos argumentos do senso comum por meio da (...) investigação da noção modal de probabilidade na linguagem comum. First, we offer theoretical resemblance of the representation of practical reasoning, beginning with the distinction between demonstrative and dialectical syllogism. We make reference to the Toulmin’s critique against to the dominant deductivism in his time. Then we give arguments to sustain the heuristic relevance of Toulmin’s model to understand the discussion about the inclusion of default logics in the representation of ordinary reasoning. We assert that the Toulminian analytic design allows to understand, with methodical clarity, the defeasibility of common sense arguments by means of the investigation of the modal notion of probability in ordinary language. (shrink)

Observational and experimental discoveries of new factual entities such as objects, systems, or processes, are major contributors to some advances in the life sciences. Yet, whereas discovery of theories was extensively deliberated by philosophers of science, very little philosophical attention was paid to the discovery of factual entities. This paper examines historical and philosophical aspects of the experimental discovery by Carl Woese of archaea, prokaryotes that comprise one of the three principal domains of the phylogenetic tree. Borrowing Kuhn’s terminology, this (...) discovery of a major biological entity was made during a ‘normal science’ project of building molecular taxonomy for prokaryotes. Unexpectedly, however, an observed anomaly instigated the discovery of archaea. Substantiation of the existence of the new archaeal entity and consequent reconstruction of the phylogenetic tree prompted replacement of a long-held model of a prokarya and eukarya bipartite tree of life by a new model of a tripartite tree comprising of bacteria, archaea, and eukarya. This paper explores the history and philosophical implications of the progression of Woese’s project from normal science to anomaly-instigated model-changing discovery. It is also shown that the consequential discoveries of RNA splicing and of ribozymes were similarly prompted by unexpected irregularities during normal science activities. It is thus submitted that some discoveries of factual biological entities are triggered by unforeseen observational or experimental anomalies. (shrink)

The paper investigates possible readings of the later Heisenberg's remarks on the nature of quantum states. It discusses, in particular, whether Heisenberg should be seen as a proponent of the epistemic conception of states – the view that quantum states are not descriptions of quantum systems but rather reflect the state assigning observers' epistemic relations to these systems. On the one hand, it seems plausible that Heisenberg subscribes to that view, given how he defends the notorious "collapse of the wave (...) function" by relating it to a sudden change in the epistemic situation of the observer registering a measured result. On the other hand, his remarks on quantum probabilities as "potentia" or "objective tendencies" are difficult to reconcile with such a reading. The accounts that are attributed to Heisenberg by the different possible readings considered are subjected to closer scrutiny; at the same time, their respective virtues and problems are discussed. _German_ Diese Arbeit untersucht mögliche Lesarten von Heisenbergs späten Bemerkungen über die Natur von Quantenzuständen. Insbesondere wird die Frage diskutiert, ob Heisenberg als Vertreter der epistemischen Auffassung von Quantenzuständen gelten kann – der Idee, dass Quantenzustände nicht Beschreibungen der objektiven Eigenschaften von Quantensystemen sind sondern die epistemischen Beziehungen von Beobachtern zu diesen Systemen widerspiegeln. Einerseits erscheint es plausibel, dass Heisenberg dieser Sichtweise zustimmt, wenn man sich ansieht, wie er den berüchtigten,,Kollaps der Wellenfunktion" verteidigt, indem er ihn mit einer plötzlichen Änderung in der Kenntnis des ein Messergebnis registrierenden Beobachters in Zusammenhang bringt. Andererseits sind seine Bemerkungen über quantenmechanische Wahrscheinlichkeiten als,,Potentia" oder,,objektive Tendenzen" mit einer solchen Lesart nur schwer in Einklang zu bringen. Die Positionen, die Heisenberg den verschiedenen möglichen Lesarten zufolge vertritt, werden eingehenden Untersuchungen unterzogen; gleichzeitig werden ihre jeweiligen Vorzüge und Probleme diskutiert. (shrink)

Memory skepticism denies our memory beliefs could have any notable epistemic good. One route to memory skepticism is to challenge memory’s epistemic trustworthiness, that is, its functioning in a way necessary for it to provide epistemic justification. In this paper we develop and respond to this challenge. It could threaten memory in such a way that we altogether lack doxastic attitudes. If it threatens memory in this way, then the challenge is importantly self-defeating. If it does not threaten memory in (...) this way, then the challenge leaves a foundation for an inference to the best explanation response, one we articulate and support. (shrink)

A general form is proposed for epistemological theories, the relevant factors being: the family of epistemic judgments, the epistemic state, the epistemic commitment, and the family of possible epistemic inputs. First a simple theory is examined in which the states are probability functions, and the subject of probability kinematics introduced by Richard Jeffrey is explored. Then a second theory is examined in which the state has as constituents a body of information and a recipe that determines the accepted epistemic judgments (...) on the basis of this corpus. Through an examination of several approaches to the statistical syllogism, a relation is again established with Jeffrey's generalized conditionalization. (shrink)