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  1. Is More Choice Better than Less?Gerald Dworkin - 1982 - Midwest Studies in Philosophy 7 (1):47-61.
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  • Genetic ties: Are they morally binding?Giuliana Fuscaldo - 2006 - Bioethics 20 (2):64–76.
    ABSTRACT Does genetic relatedness define who is a mother or father and who incurs obligations towards or entitlements over children? While once the answer to this question may have been obvious, advances in reproductive technologies have complicated our understanding of what makes a parent. In a recent publication Bayne and Kolers argue for a pluralistic account of parenthood on the basis that genetic derivation, gestation, extended custody and sometimes intention to parent are sufficient (but not necessary) grounds for parenthood.1 Bayne (...)
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  • (1 other version)Shaping future children: Parental rights and societal interests.Dan W. Brock - 2005 - Journal of Political Philosophy 13 (4):377–398.
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  • When the Milk of Human Kindness Becomes a Luxury Good.Inmaculada de Melo-Martin - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (1):159-165.
    A new reprogenetic technology, mitochondrial replacement, is making its appearance and, unsurprisingly given its promise to wash off our earthly stains --or at least the scourges of sexual reproduction--, John Harris finds only reasons to celebrate this new scientific feat.1 In fact, he finds mitochondrial replacement techniques (MRTs) so “unreservedly welcome” that he believes those who reject them suffer from “a large degree of desperation and not a little callousness.”2 Believing myself to be neither desperate nor callous, but finding myself (...)
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  • (1 other version)Response to “Entitlement to Cloning” by Timothy Murphy (CQ Vol 8, No 3) and “Cloning and Infertility” by Carson Strong (CQ Vol 7, No 3). [REVIEW]Jean E. Chambers - 2001 - Cambridge Quarterly of Healthcare Ethics 10 (2):194-204.
    Carson Strong argues, in that if cloning of humans by somatic cell nuclear transfer were to become a safe procedure, then infertile couples should have access to it as a last resort. He lists six reasons such couples might desire genetically related children. Of these, two are relevant to justifying their access to cloning—namely, that they want to jointly participate in the creation of a person, and that having a genetically related child would constitute an affirmation of their mutual love. (...)
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  • (1 other version)Response to “Clone Alone” by Carson Strong and “Are There Limits to the Use of Reproductive Cloning” by Timothy Murphy - Equal Access to Cloning?Jean Chambers - 2002 - Cambridge Quarterly of Healthcare Ethics 11 (2):169-179.
    Carson Strong's article “Cloning and Infertility” has initiated a conversation in this journal about the ethical and policy issues surrounding the question of who, if anyone, should be allowed access to human reproductive cloning technology, should somatic cell nuclear transfer ever become technically feasible and safe. Strong's position in that article is that infertile opposite sex couples for whom cloning is the last resort for having a genetically related child are the only people who should be granted access to such (...)
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  • Genome editing and assisted reproduction: curing embryos, society or prospective parents?Giulia Cavaliere - 2018 - Medicine, Health Care and Philosophy 21 (2):215-225.
    This paper explores the ethics of introducing genome-editing technologies as a new reproductive option. In particular, it focuses on whether genome editing can be considered a morally valuable alternative to preimplantation genetic diagnosis (PGD). Two arguments against the use of genome editing in reproduction are analysed, namely safety concerns and germline modification. These arguments are then contrasted with arguments in favour of genome editing, in particular with the argument of the child’s welfare and the argument of parental reproductive autonomy. In (...)
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  • Cloning and Infertility.Carson Strong - 1998 - Cambridge Quarterly of Healthcare Ethics 7 (3):279-293.
    Although there are important moral arguments against cloning human beings, it has been suggested that there might be exceptional cases in which cloning humans would be ethically permissible. One type of supposed exceptional case involves infertile couples who want to have children by cloning. This paper explores whether cloning would be ethically permissible in infertility cases and the separate question of whether we should have a policy allowing cloning in such cases. One caveat should be stated at the beginning, however. (...)
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  • (1 other version)Shaping Future Children: Parental Rights and Societal Interests.Dan W. Brock - 2005 - Journal of Political Philosophy 13 (4):377-398.
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  • Human Nuclear Genome Transfer : Clearing the Underbrush.Françoise Baylis - 2016 - Bioethics 31 (1):7-19.
    In this article, I argue that there is no compelling therapeutic ‘need’ for human nuclear genome transfer to prevent mitochondrial diseases caused by mtDNA mutations. At most there is a strong interest in this technology on the part of some women and couples at risk of having children with mitochondrial disease, and perhaps also a ‘want’ on the part of some researchers who see the technology as a useful precedent – one that provides them with ‘a quiet way station’ in (...)
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  • Should Mitochondrial Donation Be Anonymous?John B. Appleby - 2018 - Journal of Medicine and Philosophy 43 (2):261-280.
    Currently in the United Kingdom, anyone donating gametes has the status of an open-identity donor. This means that, at the age of 18, persons conceived with gametes donated since April 1, 2005 have a right to access certain pieces of identifying information about their donor. However, in early 2015, the UK Parliament approved new regulations that make mitochondrial donors anonymous. Both mitochondrial donation and gamete donation are similar in the basic sense that they involve the contribution of gamete materials to (...)
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  • Lesbian shared biological motherhood: the ethics of IVF with reception of oocytes from partner.Kristin Zeiler & Anna Malmquist - 2014 - Medicine, Health Care and Philosophy 17 (3):347-355.
    In vitro fertilization with reception of oocytes from partners allows lesbian mothers to share biological motherhood. The gestational mother receives an egg from her partner who becomes the genetic mother. This article examines the ethics of IVF with ROPA with a focus on the welfare of the woman and the resulting child, on whether ROPA qualifies as a “legitimate” medical therapy that falls within the goals of medicine, and on the meaning and value attributed to a biologically shared bond between (...)
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  • Mitochondrial Replacement: Ethics and Identity.Anthony Wrigley, Stephen Wilkinson & John B. Appleby - 2015 - Bioethics 29 (9):631-638.
    Mitochondrial replacement techniques have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer and Maternal Spindle Transfer. It examines how questions of identity impact (...)
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  • (1 other version)Response to “Cloning and Infertility” by Carson Strong.Timothy F. Murphy - 1999 - Cambridge Quarterly of Healthcare Ethics 8 (3):364-368.
    Carson Strong has argued that if human cloning were safe it should be available to some infertile couples as a matter of ethics and law. He holds that cloning by somatic cell nuclear transfer should be available as a reproductive option for infertile couples who could not otherwise have a child genetically related to one member of the couple. In this analysis, Strong overlooks an important category of people to whom his argument might apply, couples he has not failed to (...)
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  • The Mitochondrial Replacement ‘Therapy’ Myth.Tina Rulli - 2016 - Bioethics 31 (4):368-374.
    This article argues that two forms of mitochondrial replacement therapy, maternal spindle transfer and pro-nuclear transfer, are not therapies at all because they do not treat children who are coming into existence. Rather, these technologies merely create healthy children where none was inevitable. Even if creating healthy lives has some value, it is not to be confused with the medical value of a cure or therapy. The article addresses a recent Bioethics article, ‘Mitochondrial Replacement: Ethics and Identity,’ by Wrigley, Wilkinson, (...)
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  • What Is the Value of Three‐Parent IVF?Tina Rulli - 2016 - Hastings Center Report 46 (4):38-47.
    In February 2016, the Institute of Medicine released a report, commissioned by the United States Food and Drug Administration, on the ethical and social‐policy implications of so‐called three‐parent in vitro fertilization. The IOM endorses commencement of clinical trials on three‐parent IVF, subject to some initial limitations. Also called mitochondrial replacement or transfer, three‐parent IVF is an intervention comprising two distinct procedures in which the genetic materials of three people—the DNA of the father and mother and the mitochondrial DNA of an (...)
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  • The products of conception: the social context of reproductive choices.B. K. Rothman - 1985 - Journal of Medical Ethics 11 (4):188-195.
    This paper addresses the changing ideology regarding reproduction, an evolving American, and potentially worldwide, value system regarding children and parenthood. Children are increasingly being seen as products, and the new technology of reproduction, including the sale of reproductive material and services and especially prenatal diagnosis and selective abortion, encourage this commodification of the fetus. While the new technology does indeed offer new choices, it also creates new structures and new limitations on choice. In the contemporary American social structure, these choices (...)
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  • Review of John Robertson: Children of Choice: Freedom and the New Reproductive Technologies.[REVIEW]Laura M. Purdy - 1996 - Ethics 106 (2):474-476.
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  • Pronatalism, Geneticism, and ART.Angel Petropanagos - 2017 - International Journal of Feminist Approaches to Bioethics 10 (1):119-147.
    In this essay, I argue that pronatalism—a social bias in favor of gestational motherhood—and geneticism—a social bias in favor of genetic motherhood—are conceptually and operationally distinct social forces that influence some women's reproductive decision making. Each of these social forces shapes the reproductive landscape, relates differently to women's identities, and causes different social stigmatization and harm. Pronatalism and geneticism warrant feminist concern because they can compromise some women's reproductive autonomy and well-being. I suggest that combating pronatalism and geneticism will require (...)
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  • Resource Allocation, Treatment, Disclosure, and Mitochondrial Replacement Techniques: Some Comments on de Melo-Martin and Harris.César Palacios-gonzález - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (2):278-287.
    Some Comments on de Melo-Martin and Harris.
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  • Mitochondrial replacement techniques: egg donation, genealogy and eugenics.César Palacios-González - 2016 - Monash Bioethics Review 34 (1):37-51.
    Several objections against the morality of researching or employing mitochondrial replacement techniques have been advanced recently. In this paper, I examine three of these objections and show that they are found wanting. First I examine whether mitochondrial replacement techniques, research and clinical practice, should not be carried out because of possible harms to egg donors. Next I assess whether mitochondrial replacement techniques should be banned because they could affect the study of genealogical ancestry. Finally, I examine the claim that mitochondrial (...)
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  • Multiplex parenting: IVG and the generations to come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation and (...)
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  • Does egg donation for mitochondrial replacement techniques generate parental responsibilities?César Palacios-González - 2018 - Journal of Medical Ethics 44 (12):817-822.
    Children created through mitochondrial replacement techniques (MRTs) are commonly presented as possessing 50% of their mother’s nuclear DNA, 50% of their father’s nuclear DNA and the mitochondrial DNA of an egg donor. This lab-engineered genetic composition has prompted two questions: Do children who are the product of an MRT procedure have threegeneticparents? And, do MRT egg donors have parental responsibilities for the children created? In this paper, I address the second question and in doing so I also address the first (...)
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  • Are there moral differences between maternal spindle transfer and pronuclear transfer?César Palacios-González - 2017 - Medicine, Health Care and Philosophy 20 (4):503-511.
    This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer and pronuclear transfer. Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, (...)
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  • Is Mitochondrial Donation Germ‐Line Gene Therapy? Classifications and Ethical Implications.Anthony Wrigley & Ainsley J. Newson - 2016 - Bioethics 31 (1):55-67.
    The classification of techniques used in mitochondrial donation, including their role as purported germ-line gene therapies, is far from clear. These techniques exhibit characteristics typical of a variety of classifications that have been used in both scientific and bioethics scholarship. This raises two connected questions, which we address in this paper: how should we classify mitochondrial donation techniques?; and what ethical implications surround such a classification? First, we outline how methods of genetic intervention, such as germ-line gene therapy, are typically (...)
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  • (1 other version)Response to “Cloning and Infertility” by Carson Strong - Entitlement to Cloning.Timothy F. Murphy - 1999 - Cambridge Quarterly of Healthcare Ethics 8 (3):364-368.
    Carson Strong has argued that if human cloning were safe it should be available to some infertile couples as a matter of ethics and law. He holds that cloning by somatic cell nuclear transfer should be available as a reproductive option for infertile couples who could not otherwise have a child genetically related to one member of the couple. In this analysis, Strong overlooks an important category of people to whom his argument might apply, couples he has not failed to (...)
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  • (1 other version)Genes, Women, Equality.Jennifer A. Parks - 2005 - Hypatia 20 (2):200-202.
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  • Reproductive Autonomy as Self-Making: Procreative Liberty and the Practice of Ethical Subjectivity.Catherine Mills - 2013 - Journal of Medicine and Philosophy 38 (6):639-656.
    In this article, I consider recent debates on the notion of procreative liberty, to argue that reproductive freedom can be understood as a form of positive freedom—that is, the freedom to make oneself according to various ethical and aesthetic principles or values. To make this argument, I draw on Michel Foucault’s later work on ethics. Both adopting and adapting Foucault’s notion of ethics as a practice of the self and of liberty, I argue that reproductive autonomy requires enactment to gain (...)
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  • From Chance to Choice: Genetics and Justice.Allen Buchanan, Dan W. Brock, Norman Daniels & Daniel Wikler - 2000 - Cambridge University Press.
    This book, written by four internationally renowned bioethicists and first published in 2000, was the first systematic treatment of the fundamental ethical issues underlying the application of genetic technologies to human beings. Probing the implications of the remarkable advances in genetics, the authors ask how should these affect our understanding of distributive justice, equality of opportunity, the rights and obligations as parents, the meaning of disability, and the role of the concept of human nature in ethical theory and practice. The (...)
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  • (1 other version)Human Rights as Fundamental Conditions for a Good Life.S. Matthew Liao - 2015 - In The Right to Be Loved. New York, US: Oxford University Press USA.
    What grounds human rights? How do we determine that something is a genuine human right? This chapter offers a new answer: human beings have human rights to the fundamental conditions for pursuing a good life. The fundamental conditions for pursuing a good life are certain goods, capacities, and options that human beings qua human beings need whatever else they qua individuals might need in order to pursue a characteristically good human life. This chapter explains how this Fundamental Conditions Approach is (...)
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  • Introduction.S. Matthew Liao - 2015 - In The Right to Be Loved. New York, US: Oxford University Press USA.
    The book’s introduction points out that many international declarations claim that children have a right to be loved, but that philosophically speaking, there are a number of reasons to question whether there is in fact such a right. The introduction then lays out a plan to show that children have a right to be loved by answering questions such as whether children can have rights, what grounds the right to be loved, whether love is an appropriate object of a right, (...)
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  • Do Mitochondrial Replacement Techniques Affect Qualitative or Numerical Identity?S. Matthew Liao - 2016 - Bioethics 31 (1):20-26.
    Mitochondrial replacement techniques, known in the popular media as 'three-parent' or 'three-person' IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of (...)
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  • (1 other version)Response to “Clone Alone” by Carson Strong and “Are There Limits to the Use of Reproductive Cloning” by Timothy Murphy. [REVIEW]Jean E. Chambers - 2002 - Cambridge Quarterly of Healthcare Ethics 11 (2):169-179.
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  • (1 other version)Response to “Entitlement to Cloning” by Timothy Murphy (CQ Vol 8, No 3) and “Cloning and Infertility” by Carson Strong (CQ Vol 7, No 3) May a Woman Clone Herself? [REVIEW]Jean E. Chambers - 2001 - Cambridge Quarterly of Healthcare Ethics 10 (2):194-204.
    Carson Strong argues, in that if cloning of humans by somatic cell nuclear transfer were to become a safe procedure, then infertile couples should have access to it as a last resort. He lists six reasons such couples might desire genetically related children. Of these, two are relevant to justifying their access to cloning—namely, that they want to jointly participate in the creation of a person, and that having a genetically related child would constitute an affirmation of their mutual love. (...)
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  • Germline Modification and the Burden of Human Existence.John Harris - 2016 - Cambridge Quarterly of Healthcare Ethics 25 (1):6-18.
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  • The (Re) Production of the Genetically Related Body in Law, Technology and Culture: Mitochondria Replacement Therapy.Danielle Griffiths - 2016 - Health Care Analysis 24 (3):196-209.
    Advances in medicine in the latter half of the twentieth century have dramatically altered human bodies, expanding choices around what we do with them and how they connect to other bodies. Nowhere is this more so than in the area of reproductive technologies. Reproductive medicine and the laws surrounding it in the UK have reconfigured traditional boundaries surrounding parenthood and the family. Yet culture and regulation surrounding RTs have combined to try to ensure that while traditional boundaries may be pushed, (...)
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  • Two concepts of liberty.Ronald Dworkin - 1991 - In Isaiah Berlin, Edna Ullmann-Margalit & Avishai Margalit (eds.), Isaiah Berlin: a celebration. Chicago: University of Chicago Press. pp. 100--109.
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  • How to solve the non-identity problem.David Boonin - 2008 - Public Affairs Quarterly 22 (2):129-159.
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  • Genetic Affinity and the Right to ‘Three-parent IVF’.G. Owen Schaefer & Markus Labude - 2017 - Journal of Assisted Reproduction and Genetics 34 (12):1577-1580.
    With the recent report of a live birth after use of Mitochondrial replacement therapy, sometimes called ‘Three-parent IVF’, the clinical application of the technique is fast becoming a reality. While the United Kingdom allows the procedure under regulatory scrutiny, it remains effectively outlawed in many other countries. We argue that such prohibitions may violate individuals’ procreative rights, grounded in individuals’ interest in genetic affinity. The interest in genetic affinity was recently endorsed by Singapore’s highest court, reflecting an emphasis on the (...)
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  • Why Have Children?: The Ethical Debate.Christine Overall - 2012 - MIT Press.
    In contemporary Western society, people are more often called upon to justify the choice not to have children than they are to supply reasons for having them. In this book, Christine Overall maintains that the burden of proof should be reversed: that the choice to have children calls for more careful justification and reasoning than the choice not to. Arguing that the choice to have children is not just a prudential or pragmatic decision but one with ethical repercussions, Overall offers (...)
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  • Powers of Freedom: Reframing Political Thought.Nikolas Rose, Professor Nikolas Rose & Rose - 1999 - Cambridge University Press.
    Powers of Freedom, first published in 1999, offers a compelling approach to the analysis of political power which extends Foucault's hypotheses on governmentality in challenging ways. Nikolas Rose sets out the key characteristics of this approach to political power and analyses the government of conduct. He analyses the role of expertise, the politics of numbers, technologies of economic management and the political uses of space. He illuminates the relation of this approach to contemporary theories of 'risk society' and 'the sociology (...)
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  • The Future of Human Nature.Jurgen Habermas - 2004 - Philosophy 79 (309):483-486.
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