Since the Supreme Court upheld the partial birth abortion ban in 2007, more U.S. abortion providers have begun performing intraamniotic digoxin injections prior to uterine dilation and evacuations. These injections can cause medical harm to abortion patients. Our objective is to perform an in-depth bioethical analysis of this procedure, which is performed mainly for the provider’s legal benefit despite potential medical consequences for the patient.

The phenomenon of “dirty hands” is often held to be endemic to political life. Success in politics—it has been argued—requires a willingness to sacrifice our moral principles in order to pursue worthwhile goals. I argue that the tension between morality and politics goes deeper than this. The very existence of “politics” requires that morality is routinely violated because political community, within which political discourse is possible, is based on denying the moral claims of non-members. Political community requires borders and borders (...) require keeping outsiders out. Yet there is no justification that we can provide to someone outside of our political community as to why they are denied membership. The price of political community is therefore the unjust exclusion of others. In a world characterised by the movement of peoples as a result of large-scale and systematic international injustices, this exclusion often involves acts that violate important obligations of compassion and respect. Thus, “we” are the barbarians my title refers to. In order for political community to exist, we must act like barbarians at the gates. A problem of “dirty hands” therefore lies at the very foundation of political community. (shrink)

The somewhat old-fashioned concept of philosophical categories is revived and put to work in automated ontology building. We describe a project harvesting knowledge from Wikipedia’s category network in which the principled ontological structure of Cyc was leveraged to furnish an extra layer of accuracy-checking over and above more usual corrections which draw on automated measures of semantic relatedness.

The Tannhäuser Gate. Architecture in science fiction films of the second half of the 20th and the beginning of the 21st century as a component of utopian and dystopian projections of the future. -/- The films of science fiction genre from the second half of the 20th and early 21st century contained many visions of the future, which were at the same time a reflection on the achievements and deficiencies of modern times. In 1960s, cinematographic works were dominated by optimism (...) and faith in the possibility of never-ending progress. The disappearance of political divisions between the blocs of states and the joint exploration of the cosmos was foreseen. The designers undertook cooperation with scientists, which manifested itself in showing cosmic constructions far exceeding the real technical capabilities. Starting from the 1970s, pessimism and the belief that the future will bring, above all, the intensification of negative phenomena of the present began to grow in films. Fears of the future were connected with indicating various possible defects and insoluble contradictions between them. When, therefore, some dystopian visions illustrated the threat of increase in crime, others depicted the future as saturated with state control mechanisms and the prevalence of surveillance. The fears shown on the screens were also aroused by the growth of large corporations, especially by their gaining political influence or staying outside the system of democracy. The authors of the films also presented their suspicions related to the creation of new types of weapons by corporations, the use of which might breach the current legal norms. Particular objections concerned research on biological weapons and the possible spread of lethal viruses. The development of robotics and research into artificial intelligence, which must have resulted in the appearance of androids and inevitable tensions in their relations with humans, also triggered fear. Another problem for film-makers has become hybrids that are a combination of people and electronic parts. Scriptwriters and directors likewise considered the development of genetic engineering, which led to the creation of mutant human beings. A number of film dystopias contemplated the possibility of the collapse of democratic systems and the development of authoritarian regimes in their place, often based on broad public support. This kind of dystopia also includes films presenting the consequences of contemporary hedonism and consumerism. The problem is, however, that works critical of these phenomena were themselves advertisements for attractive products. (shrink)

In his 2018 essay Down to Earth, the French philosopher Bruno Latour proposes a hypothesis that connects a number of contemporary issues, ranging from climate denialism to deregulation and growing inequality. While his hypothesis, namely that the elites act as if they live in another world and are leaving the rest of the world behind, might seem like a conspiracy theory, I will argue that there is a way to make sense of it. To do so, I will turn to (...) two other authors, Timothy Mitchell and Shoshana Zuboff, to highlight the kind of logic that Latour seems to have in mind. In the final section, I will propose to capture the commonalities of these authors through the concept of shifting reciprocities and will return to Latour’s political plea to define one’s territories, reinterpreted as reciprocities. (shrink)

A vehicle boom barrier gate system is one of the recently developed technologies operating at the entrances to the restricted areas. This paper aims to design and control of vehicle’s boom barrier gate system using robust augmentation technique. 2 H optimal and H  synthesis controllers are used to improve the performance of the system. The open loop response analysis of the vehicle boom barrier gate system shows that the input of the system need to be improved. Comparison of the (...) vehicle boom barrier gate system with 2 H optimal and H  synthesis controllers have been done to track a set point desired angular position using a step and operational open and close input signals and a promising results have been observed. (shrink)

In this essay, we explore how digital publishing can intervene in these processes and serve as a form of feminist activism. We take as our focus the Journal of Interactive Technology and Pedagogy (JITP), founded in 2011 to expand the perspectives and standpoints that count as scholarly knowledge production and provide graduate students with editorial experience. As three long-standing members of the journal’s editorial collective, we have firsthand knowledge of how JITP’s publishing methods were developed through debate, struggle, and dialogue, (...) including many missteps and failures along the way. We argue that JITP's collaborative knowledge practices of inclusive editorial governance, open access, and open peer review are fundamentally feminist, as they diversify scholarly voices and increase access to the material channels in and through which knowledge circulates. At stake in our reflective analysis is a broader claim that extends beyond the parameters of our work with one particular journal: that feminist digital publishing methods can expand what counts as knowledge production. (shrink)

Translation of Nagarjuna's -Treatise on the Twelve Gates- as well as fazang's commentary on that treatise.

In the first part of this paper we will consider the likely extent of Spinoza’s exposure to Kabbalistic literature as he was growing up in Amsterdam. In the second part we will closely study several texts in which Spinoza seems to engage with Kabbalistic doctrines. In the third and final part we will study the role of the two crucial doctrines of emanation and pantheism (or panentheism), in Spinoza’s system and in the Kabbalistic literature.

Father André Scrima is one of the most enigmatic figures of the Romanian Orthodox Church. Everything related to him passes as extraordinary. He was an exception among the Romanian intellectuals who suffered under communism. Beyond that, his journeys and spiritual experiences possess something indescribable, almost sacramental. His presence overwhelmed those who met him and his writings retained this trait. The present study focuses on Scrima’s Christology, highlighting its uniqueness and its practical implications. Although Scrima does not dedicate a book to (...) the subject, all of his writings refer to it. However, due to his distinctiveness, it is difficult to organize his Christology in a systematic way. The most lucrative approach is to group his texts along the hermeneutical moments that define his writing: images, stories and stances. In Scrima’s logic, all words/signs are the very synthesis of a spiritual experience, all stories develop the theo-logical synthesis of the signs, and the relation between the stories forms the tradition as a set of interrogations and communitarian commitments. If we evaluate Scrima’s Christology in this manner, we do not come to a system, but to a succession of images. The core of these images re-mains the same, Jesus Christ, yet it is seen in nuances that unveil His beauty – Stranger, Gate, Logos, Name above all names –, in an unpredictable play of perspectives. It can be said that Scrima’s approach resembles a kaleidoscope, which, by using mirrors and light, gives an insight to the unsuspected possibilities of all fixed forms. (shrink)

My research is a result of accumulated provocation of obsolete and paralyzing education that has been frozen since the middle ages. We have to admit that before the pandemic, education was already in crisis. Governments have been ignoring to adopt any comprehensive plan to reform the educational systems till it has been unprecedently disrupted by COVID-19. I try through this paper to make a global call for governments to immediately start cooperating together for setting international qualifications framework that best suit (...) future competencies. This call should be prioritized on the world agenda. It would be more plausible for governments, UNESCO and other education stakeholders to seize the opportunity of the 2020 disruption of life cycle for the maximum benefit of humanity. For this to happen we need exceptional leaders with extraordinary vision to transform education instead of ensuring children can keep learning and that every single child returns to school after the pandemic. Another challenge to be expected is the reduction in education budgets being under pressure as governments shift spending towards the health and economic response to the pandemic. The impact of schools closing on a generation of children will be immense on the long term. We must act now to save the education and life chances of generations of youth. At this time of unprecedented crisis, the world must come together to protect education and put it at the very heart of the global recovery effort. Recovery, not as before but as convenient and sustainable with the perspective requirements. It is time to expose youth to real life experiences; we need our children to learn about finance from characters like Jef Bezos or Bill Gates or Mukesh Ambani; to learn about psychology from John Anderson, Eliot Aronson and Ahmed Ukasha; to know approaches of math and physics as Elon Musk and Steve Wozniak. We shouldn't settle for less when it comes to building minds and souls of our children. With all due respect to teachers and university professors, they are not the only best option for qualifying and training our youth for tomorrow's challenges. However, those entrepreneurs are not teachers or willing to be, education specialists and strategists are required to set the vision and the procedures required to pave the way for highly practical competencies framework. Analgesics are no longer feasible. (shrink)

nanological gates, in order to design nano-scale computers with dual-scale capabilities. All living biological systems function due to the molecular interactions of different subsystems. Molecular components (proteins and nucleic acids, lipids and carbohydrates, DNA and RNA) can be used as an inspirational strategy on how to design high-performance NEMS and MEMS that have the required features and characteristics. Considered. In addition, analytical and numerical methods are available for dynamic analysis and three-dimensional geometry, bonding and other properties of atoms and (...) molecules. Thus, electromagnetic and mechanical, and other physical and chemical properties can be studied. Nanostructures and nanosystems can be widely used in medicine and health. Possible applications of nanotechnology include: drug synthesis and drug delivery (therapeutic potential is greatly increased due to the effective direct delivery of new types of drugs to specific sites in the body), nanosurgery and nanotherapy Synthesis and detection of genomes, nano-scale stimuli and sensors (diagnosis and prevention of disease), design and implantation of non-rejection artificial organs and design of high performance nanomaterials. It is important that these technologies change the manufacture of materials, devices and systems. (shrink)

Within the last decade, epistemic injustice has been a valuable framework for those working on exposing oppressive practices within the healthcare system. As this work has evolved, new terminology has been added to the epistemic injustice literature to bring to light previously obscured epistemic harms in healthcare practices. This paper aims to explore an important concept that has not received the attention it deserves: epistemic isolation. By developing Ian Kidd and Havi Carel’s concept of epistemic isolation, a new range of (...) epistemic harms are brought to the fore, as some of the most marginalised in our society are forced to operate from positions of ignorance. In the words of Kidd and Carel, epistemic isolation occurs in ‘situations where a person or group lacks the knowledge of, or means of access to, particular information; for instance, if they live within a politically repressive society which forbids access to the necessary sources of information in order to protect the government’s hegemony’ (183–184). This paper will demonstrate that such epistemic isolation is uniquely devastating for those with psychiatric illness, exacerbating their already challenging circumstances. (shrink)

The work described in this report is motivated by the desire to test the expressive possibilities of action language C+. The Causal Calculator (CCalc) is a system that answers queries about action domains described in a fragment of that language. The Zoo World and the Traffic World have been proposed by Erik Sandewall in his Logic Modelling Workshop—an environment for communicating axiomatizations of action domains of nontrivial size. -/- The Zoo World consists of several cages and the exterior, gates (...) between them, and animals of several species, including humans. Actions in this domain include moving within and between cages, opening and closing gates, and mounting and riding animals. The Traffic World includes vehicles moving continuously between road crossings subject to a number of restrictions, such as speed limits and keeping a fixed safety distance away from other vehicles on the road. We show how to represent the two domains in the input language of CCalc, and how to use CCalc to test these representations. (shrink)

Is the mathematical function being computed by a given physical system determined by the system’s dynamics? This question is at the heart of the indeterminacy of computation phenomenon (Fresco et al. [unpublished]). A paradigmatic example is a conventional electrical AND-gate that is often said to compute conjunction, but it can just as well be used to compute disjunction. Despite the pervasiveness of this phenomenon in physical computational systems, it has been discussed in the philosophical literature only indirectly, mostly with reference (...) to the debate over realism about physical computation and computationalism. A welcome exception is Dewhurst’s ([2018]) recent analysis of computational individuation under the mechanistic framework. He rejects the idea of appealing to semantic properties for determining the computational identity of a physical system. But Dewhurst seems to be too quick to pay the price of giving up the notion of computational equivalence. We aim to show that the mechanist need not pay this price. The mechanistic framework can, in principle, preserve the idea of computational equivalence even between two different enough kinds of physical systems, say, electrical and hydraulic ones. (shrink)

Continued urbanization, along with anthropogenic global warming, has and will increase land surface temperature and air temperature anomalies in urban areas when compared to their rural surroundings, leading to Urban Heat Islands (UHI). UHI poses environmental and health risks, affecting both psychological and physiological aspects of human health. Thus, using a deep learning approach that considers morphological variables, this study predicts UHI intensity in 69 European cities from 2007 to 2021 and projects UHI impacts for 2050 and 2080. The research (...) employs Artificial Neural Networks, Deep Neural Networks, and Gated Recurrent Units, combining high-resolution 3D urban models with environmental data to analyze UHI trends. The results indicate strong associations between urban form, weather patterns, and UHI intensity, highlighting the need for customized urban planning and policy measures to reduce UHI impacts and foster sustainable urban settings. This research enhances understanding of UHI dynamics and serves as a valuable tool for urban planners and policymakers to address the challenges of climate change, urbanization, and air pollution, ultimately aiding in the improvement of health outcomes and building energy consumption. Moreover, the methodology effectively demonstrates the ability of the GRU to link its scores with UHI projections, offering crucial insights into potential health impacts. (shrink)

Public policymakers and institutional decision-makers routinely face questions about whether interventions “work”: does universal basic income improve people’s welfare and stimulate entrepreneurial activity? Do gated alleyways reduce burglaries or merely shift the crime burden to neighbouring communities? What is the most cost-effective way to improve students’ reading abilities? These are empirical questions that seem best answered by looking at the world, rather than trusting speculations about what will be effective. Evidence-based policy (EBP) is a movement that concretizes this intuition. It (...) maintains that policy should be based on evidence of “what works.” Not any evidence will do, however. Following on the heels of its intellectual progenitor, evidence-based medicine (EBM), EBP insists on the use of high-quality evidence produced in accordance with rigorous methodological standards. Though intuitively compelling, EBP has attracted significant criticism from methodologists, political scientists, and philosophers. This chapter provides a critical overview of EBP through a philosophical lens, reviewing and discussing some of the most pressing challenges that EBP faces and outlining some proposals for improving it. I first provide a brief overview of EBP and distinguish a broader and narrower understanding of it. I then review existing lines of criticism of EBP, two of which are considered in detail. The first elaborates how EBP struggles with extrapolation, that is, the use of evidence from study populations to make inferences about the effects of policies on novel target populations. The second maintains that EBP’s methodological tenets are deeply entwined with moral and political values, which can threaten EBP’s promise to promote objectivity in policymaking. Finally, I make some proposals for how EBP could be improved going forward. (shrink)

The Hodgkin–Huxley (HH) model of the action potential is a theoretical pillar of modern neurobiology. In a number of recent publications, Carl Craver ([2006], [2007], [2008]) has argued that the model is explanatorily deficient because it does not reveal enough about underlying molecular mechanisms. I offer an alternative picture of the HH model, according to which it deliberately abstracts from molecular specifics. By doing so, the model explains whole-cell behaviour as the product of a mass of underlying low-level events. The (...) issue goes beyond cellular neurobiology, for the strategy of abstraction exhibited in the HH case is found in a range of biological contexts. I discuss why it has been largely neglected by advocates of the mechanist approach to explanation. 1 Introduction2 A Primer on the HH Model2.1 The basic qualitative picture2.2 The quantitative model3 Interlude: What Did Hodgkin and Huxley Think?4 Craver’s View4.1 Mechanistic explanation4.2 Sketches4.3 Craver's view: The HH model as a mechanism sketch5 An Alternative View of the HH Model5.1 Another look at the equations5.2 The discrete-gating picture5.3 The road paved by Hodgkin and Huxley5.4 Summary and comparison to Craver6 Conclusion: The HH Model and Mechanistic Explanation6.1 Sketches and abstractions6.2 Why has aggregative abstraction been overlooked? (shrink)

The aim of this paper is to investigate Nishida Kitarō’s way of philosophizing in the light of the concept of “transition” in order to deepen our understanding of both Nishida’s philosophy and our thinking about and in transitions, using the concept of “boundary” or “border” (Grenze) as a catalyst. For that purpose, we focus on Nishida’s essay “Place” (「場所」), passing through different parts of the text as if through successive gates on a path of transition between one place and (...) the next, until we reach the final place of “absolute nothingness.” Dwelling on this place, we turn our attention to its internal structure and try to depict it along the outlines of a boundary, following the movements taking place in Nishida’s essay. The second part proposes an interpretation of the place of nothingness as an interminable practice of boundary-crossing that doesn’t come to a halt in a final, all-encompassing place, but dynamically situates itself on countless intersecting planes. After a more or less abstract analysis of the concept of “boundary,” we will apply and concretize this approach by using the example of the skin. To this end, we expose five main features of the skin as boundary: permeability, enclosure, excessiveness, interstitiality and reciprocal self-formation. (shrink)

Various philosophers authors have argued—on the basis of powerful examples—that we can have compelling moral or practical reasons to believe, even when the evidence suggests otherwise. This paper explores an alternative story, which still aims to respect widely shared intuitions about the motivating examples. Specifically, the paper proposes that what is at stake in these cases is not belief, but rather acceptance—an attitude classically characterized as taking a proposition as a premise in practical deliberation and action. I suggest that acceptance’s (...) theoretical usefulness in the ethics of belief has been hidden by its psychological obscurity. I thus aim to develop an empirically adequate and mechanistically specific psychological profile of acceptance. I characterize acceptance as centrally involving a cognitive gating function, in which we prevent a target belief state from having its characteristic downstream effects on reasoning, cognition, and action, and restructure those downstream processes. I then argue that there is substantial empirical support for the existence of the cognitive mechanisms needed to instantiate this view, coming from the science of emotion regulation. I argue that acceptance involves deploying the same mechanisms used in emotional response modulation to belief states: acceptance is doxastic response modulation. I then propose that having a better understanding of the psychological profile of acceptance leaves us better positioned to appreciate its potential usefulness for making progress on various puzzles within the ethics of belief. (shrink)

Philosophers have been talking about brain states for almost 50 years and as of yet no one has articulated a theoretical account of what one is. In fact this issue has received almost no attention and cognitive scientists still use meaningless phrases like 'C-fiber firing' and 'neuronal activity' when theorizing about the relation of the mind to the brain. To date when theorists do discuss brain states they usually do so in the context of making some other argument with the (...) result being that any discussion of what brain states are has a distinct en passant flavor. In light of this it is a goal of mine to make brain states the center of attention by providing some general discussion of them. I briefly look at the argument of Bechtel and Mundale, as I think that they expose a common misconception philosophers had about brain states early on. I then turn to briefly examining Polger's argument, as I think he offers an intuitive account of what we expect brain states to be as well as a convincing argument against a common candidate for knowledge about brain states that is currently "on the scene." I then introduce a distinction between brain states and states of the brain: Particular brain states occur against background states of the brain. I argue that brain states are patterns of synchronous neural firing, which reflects the electrical face of the brain; states of the brain are the gating and modulating of neural activity and reflect the chemical face of the brain. (shrink)

In a study drawing from both evolutionary biology and the social sciences, evidence and argument is assembled in support of the comprehensive appli- cation of selfish gene theory to the human population. With a focus on genes giving rise to characteristically-human cooperation (“cooperative genes”) in- volving language and theory of mind, one may situate a whole range of pat- terned behaviour—including celibacy and even slavery—otherwise seeming to present insuperable difficulties. Crucially, the behaviour which tends to propa- gate the cooperative genes (...) may be “at cost” to the genes of some who may be party to the cooperation itself. Explanatory insights are provided by Trivers’ parent-offspring conflict theory, Lack’s principle, and Hamilton’s kin selec- tion mechanism. A primary observation is that cooperation using language and theory of mind is itself interdependent with full human conceptualization of a world of objects and of themselves as embodied beings. Human capaci- ties inhering in, or arising out of, the ability to cooperate are also responsible for a vitally important long-term process, the domestication of animals and p- lants. The approach illuminates the difference between animal and human sexual behaviour, and the emergence of kinship systems. Again, recent pat- terns of population growth become much more explicable. It is argued that the gene is the single controlling replicator; the notion of the meme as a sec- ond independent replicator is flawed. (shrink)

‘Abandon all hope, ye who enter here’ is, as we all recognize, the inscription over the gate of Dante's hell; but we perhaps forget what precedes that memorable line. Hell, the inscription says, was built by divine power, by the highest wisdom, and by primordial love. Those of us who remember Dante's vivid picture of Farinata in the perpetually burning tombs or Ulysses in the unending and yet unconsuming flames may be able to credit Dante's idea that Hell was constructed (...) by divine power; and if we understand ‘wisdom’ in this context as denoting an intellectual virtue only, then we might agree that only divine wisdom is capable of making something like Dante's hell. (shrink)

The brain is composed of electrically excitable neuronal networks regulated by the activity of voltage-gated ion channels. Further portraying the molecular composition of the brain, however, will not reveal anything remotely reminiscent of a feeling, a sensation or a conscious experience. In classical physics, addressing the mind–brain problem is a formidable task because no physical mechanism is able to explain how the brain generates the unobservable, inner psychological world of conscious experiences and how in turn those conscious experiences steer the (...) underlying brain processes toward desired behavior. Yet, this setback does not establish that consciousness is non-physical. Modern quantum physics affirms the interplay between two types of physical entities in Hilbert space: unobservable quantum states, which are vectors describing what exists in the physical world, and quantum observables, which are operators describing what can be observed in quantum measurements. Quantum no-go theorems further provide a framework for studying quantum brain dynamics, which has to be governed by a physically admissible Hamiltonian. Comprising consciousness of unobservable quantum information integrated in quantum brain states explains the origin of the inner privacy of conscious experiences and revisits the dynamic timescale of conscious processes to picosecond conformational transitions of neural biomolecules. The observable brain is then an objective construction created from classical bits of information, which are bound by Holevo’s theorem, and obtained through the measurement of quantum brain observables. Thus, quantum information theory clarifies the distinction between the unobservable mind and the observable brain, and supports a solid physical foundation for consciousness research. (shrink)

Howard Phillips Lovecraft’s work of fiction can roughly be grouped into three distinct categories, each evoking a singular extraordinary state of mind. Poe-inspired tales of the macabre such as “The Tomb” (1917) and “The Statement of Randolph Carter” (1919) produce terror because of the atmosphere they convey and because of the particular end the main characters meet. Lovecraft’s later “Yog-Sothothery” or work in the Cthulhu Mythos tradition, including his signature pieces of weird fiction “The Call of Cthulhu” (1926) and “The (...) Shadow over Innsmouth” (1931), inspires ‘horror’ because the life-worlds of the protagonists in these stories are utterly destroyed. However, the gentleman of Providence is also known for a different sort of fiction. His Dunsanian tales—among them short stories such as “The White Ship” (1919), “Celephaïs” (1920), and the three works“ The Silver Key” (1926), The Dream-Quest of Unknown Kadath (1926–27), and “Through the Gates of the Silver Key” (1932–33; with E. Hoffmann Price), centered on the exploits of Lovecraft’s recurring character and alter ego Randolph Carter—are epitomes to this feat. These prehistoric or dreamland tales do not inspire ‘terror’ or ‘horror’; rather, they predominately seek to evoke the extraordinary state of mind called ‘wonder. This article offers a preliminary exploration of Lovecraft’s relationship with wonder, highlights what wonder is, how Lovecraft was exposed to wonder at an early age, and argues that he developed a lifelong positive relationship with this particular state of mind. (shrink)

On the long and well-worn road of many, but justifiable attempts of human to discover his origin, his trajectory as a species, and a suitable understanding consciousness, his system allowing the connection to the environment and to his own organism, the concepts and models of philosophy enunciated or experienced by millennia, meet today with modern science concepts of physics and of science of information. Based on recent discoveries of quantum physics and astrophysics, revealing a new understanding of our environment and (...) starting from some philosophical concepts on information of matter and of living structures, this work discusses the dynamics of information within the frame of the Informational Model of Consciousness as an informational system of the human body, connected both to the environment and to the body itself, to control the adaptation for survival. It is shown that consciousness is actually an informational projection in the mind of seven informational subsystems, three of which forming the operative system of consciousness for the short-term adaptation, and other three forming the programmed operating system, dedicated to the maintenance of body and to the long-term survival of species, showing various inputs and outputs of information. The seventh subsystem is the information pole, connecting the organism with the external information, especially related to the extra-sensorial properties of the mind, the human body appearing as a bipolar info-matter structure, managed by the brain. The received information is progressively integrated into the informational system of the organism, which absorbs and emanates information as a reactive system for adaptation, able to operate both with matter-related (codified) and non-matter related (virtual) information. As both connections with external and internal environment (body itself) can be described in terms of information, this model opens the gate to investigate consciousness by means of the tools of the information science, offering also answers to the philosophic “mind-body” problem and to the “hard” problem and showing correspondences with some ancient philosophies. (shrink)

Charland's article suggests that we need to think more about whether decision-making capacity is impaired in severe addiction, working from the idea that drug dealers rely on this understanding of addiction to draw in their clients. Charland argues that it is possible to make a choice without being in control (to make decisions without having decision-making capacity). I argue in support of Charland's ideas by examining the reasons supporting a medical model of addiction and its importance. (For Charland's article and (...) the full set of commentaries, please see the Research Gate link). (shrink)

The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the underlying functional specializations, for input or output of neural information, respectively. For a proper assessment of the computational capacity of pyramidal neurons, we have analyzed an extensive dataset of three-dimensional digital reconstructions from the NeuroMorphoOrg database, and quantified basic dendritic or axonal morphometric measures in different regions and layers of (...) the mouse, rat or human cerebral cortex. Physical estimates of the total number and type of ions involved in neuronal electric spiking based on the obtained morphometric data, combined with energetics of neurotransmitter release and signaling fueled by glucose consumed by the active brain, support highly efficient cerebral computation performed at the thermodynamically allowed Landauer limit for implementation of irreversible logical operations. Individual proton tunneling events in voltage-sensing S4 protein alpha-helices of Na+, K+ or Ca2+ ion channels are ideally suited to serve as single Landauer elementary logical operations that are then amplified by selective ionic currents traversing the open channel pores. This miniaturization of computational gating allows the execution of over 1.2 zetta logical operations per second in the human cerebral cortex without combusting the brain by the released heat. (shrink)

I show that the indeterminacy problem for computational structuralists is in fact far more problematic than even the harshest critic of structuralism has realised; it is not a bullet which can be bitten by structuralists as previously thought. Roughly, this is because the structural indeterminacy of logic-gates such as AND/OR is caused by the structural identity of the binary computational digits 0/1 themselves. I provide a proof that pure computational structuralism is untenable because structural indeterminacy entails absurd consequences - (...) namely, that there is only one binary computational digit. I conclude that accounting for individuation is a more important desiderata for a theory of computation than even that of triviality. -/- . (shrink)

Proposition are the material of our reasoning. Proposition are the basic building blocks of the world/thought. Proposition have intense relation with the world. World is a series of atomic facts and these facts are valued by the proposition although sentences explain the world of reality but can’t have any truth values, only proposition have truth values to describe the world in terms of assertions. Propositions are truth value bearers, the only quality of proposition is truth & falsity, that they are (...) either true or false. Proposition mirrors the world and explains how world is arranged in an orderly manner. It scans the world(object) and are composed of atomic facts experienced and can be analyzed into propositions. Propositions are the basic units of logic. The truth (affirm) and falsity (nego) are the qualities of the propositions and universality (generality) and Particularity are the quantities of the propositions. There are propositions which are neither true nor false, they are called Pseudo-Propositions and their quality are ipso-facto i.e meaningless. Propositions are used in computers with the modifications brought by the modern logicians in the form of statements or logical sentences. The truth table of the logical gates and binary operations (1,s or 0,s are due to the revolution of the modern logic or mathematical logic. It is a fact that proposition cannot change the word but it shows the relation between the object and of the word. Objectives: The objectives of this research is to explore the importance and need of propositions in logic. It also shows the analysis of propositions and how a philosopher thoughts in terms of propositions or concepts. In this research problem it is shown that propositions had been described in many ways by most of the philosophers and logicians from Aristotle to contemporary philosophers. It also analysis the contribution of the philosophers towards proposition and its relation to the world of reality. This research also describes the definition and nature of proposition. (shrink)

Synthetic biology is a field of research that concentrates on the design, construction, and modification of new biomolecular parts and metabolic pathways using engineering techniques and computational models. By employing knowledge of operational pathways from engineering and mathematics such as circuits, oscillators, and digital logic gates, it uses these to understand, model, rewire, and reprogram biological networks and modules. Standard biological parts with known functions are catalogued in a number of registries (e.g. Massachusetts Institute of Technology Registry of Standard (...) Biological Parts). Biological parts can then be selected from the catalogue and assembled in a variety of combinations to construct a system or pathway in a microbe. Through the innovative re-engineering of biological circuits and the optimization of certain metabolic pathways, biological modules can be designed to reprogram organisms to produce products or behaviors. Synthetic biology is what is known as a “platform technology”. That is, it generates highly transferrable theoretical models, engineering principles, and know-how that can be applied to create potential products in a wide variety of industries. Proponents suggest that applications of synthetic biology may be able to provide scientific and engineered solutions to a multitude of worldwide problems from health to energy. Synthetic biology research has already been successful in constructing microbial products which promise to offer cheaper pharmaceuticals such as the antimalarial synthetic drug artemisinin, engineered microbes capable of cleaning up oil spills, and the engineering of biosensors that can detect the presence of high concentrations of arsenic in drinking water. One of the potential benefits of synthetic biology research is in its application to biofuel production. It is this application which is the focus of this entry. The term “biofuel” has referred generally to all liquid fuels that are sourced from plant or plant byproducts and are used for energy necessary for transportation vehicles (Thompson 2012). Biofuels that are produced using synthetic biological techniques re-engineer microbes into biofuel factories are a subset of these. (shrink)

Deep decarbonization – slashing global greenhouse gas emissions to net-zero – now dominates global climate policy. Two recent books assess feasible routes to achieve deep decarbonization. Bill Gates’ How to Avoid a Climate Disaster explains in depth why deep decarbonization requires significant innovations in tech, and Danny Cullenward and David Victor’s Making Climate Policy Work emphasizes the importance of policy innovation (beyond carbon pricing) for driving clean tech breakthroughs. In this critical review essay, I summarize and assess both books. (...) In the final section, I raise several normative questions, which the pair of books might lead us to. (shrink)

Impulse and momentum are basic concepts of mechanics introduced in the K to 12 curricula. Despite its basic concepts, students still have difficulties understanding the topic, especially when they are out of school due to the pandemic. After reopening the gates for face–to–face classes in the Philippines, the researchers found a significant reason to conduct a lesson study to improve teaching strategies on the topic. Lesson study is a development process wherein teachers work collaboratively to improve teachers teaching capacity. (...) This study was conducted at Plaridel National High School with 23 participants from Grade 9 Newton (Set A and B). The research was conducted in two cycles using a four – phase lesson study. The research lesson was implemented using a 4A Model lesson plan and the results were taken from the analysis of the lesson study observation sheets, along with the class proficiency level. The researchers used the following strategies to improve teaching, namely; (1) showing mastery of subject matter, (2) reviewing basic mathematical operations, (3) contextualizing the lesson, (4) allowing students to answer questions in mother tongue, (5) using collaborative activities, (6) giving rewards, and (7) applying proper time management. However, the findings still showed that both sets of students achieved beginning proficiency level. Despite the implementation of these strategies, the students still lack basic knowledge of the topic and mathematical operations, and they struggle to understand it. Thus, it is recommended to plan the lesson effectively, utilize other research instruments, and collect feedback from the students. (shrink)

I present a case for a rapprochement between aspects of rationalism and scientific realism, by way of a general framework employing modal epistemology and elements of 2-dimensional semantics (2DS). My overall argument strategy is meta-inductive: The bulk of this paper establishes a “base case,” i.e., a concretely constructive example by which I demonstrate this linkage. The base case or constructive example acts as the exemplar for generating, in a constructively ‘bottom-up’ fashion, a more generally rigorous case for rationalism-realism qua modal (...) epistemology. The exemple I choose in D. Chalmers’ (2002) modal rationalism and R. Giere’s (1985, 1988) constructive realism. I show by way of a thorough analysis how Giere’s claims concerning modal scope are characterized as instances of Chalmers’ modal rationalism, both weak and strong. In essence, as I demonstrate via Chalmers’ notions, ceteris paribus the constructive realist ultimately opts for a comparatively wider gate, characterized by modal reasoning, to lead from the rooms of conceivability qua thought experiments and models, to the pastures of metaphysical possibility. Chalmers likewise tries to erect such a wider gate, in his general conceivability-possibility theses. Anti-realists, on the other hand, see a narrower passage and my contention herein is that they suffer from modal myopia, which hopefully the ‘corrective vision’ of Chalmers’ modal rationalism can restore. In the introduction and concluding sections I sketch out suggestions of constructing ‘inductive steps’ from my base case, to generate more extensively general claims regarding realism qua rationalism. -/- . (shrink)

The paradox of material implication has remained unresolved since antiquity because it was believed that the nature of implication was entailment. The article shows that this nature is opposition and therefore the name "implication" should be replaced with the name "competition". A solution to the paradox is provided along with appropriate changes in nomenclature, the addition of connectives and the postulate that the biconditional take over the role of the previous implication. In addition, changes to the nomenclature of logic (...) class='Hi'>gates reflecting the competition in electronics are proposed. (shrink)

Many differences exist between the logical relations “equality” and “equivalence”. In this monograph I point out differences that concern definition, linguistics, computational gates and tables, denotation, application, negation of terms, negation of the relation, relations to other relations, the laws of symmetry, transitivity and reflexivity, the laws of commutation and permutation, the law of tautology, the law of distribution, the law of association, propositional meaning, and “genesis”. I also point out a form of “symmetry breaking”: the negation of some (...) equality may yield some non-equality, while the negation of that non-equality might not yield the same equality. (For full access: use the website link of the title page. -- Copyright License: CC BY-NC-ND. -- DOI: 10.17026/dans-zh3-h2b2 --). (shrink)

Die Übernahme des KI-Unternehmens DeepMind durch Google für rund eine halbe Milliarde US-Dollar signalisierte vor einem Jahr, dass von der KI-Forschung vielversprechende Ergebnisse erwartet werden. Spätestens seit bekannte Wissenschaftler wie Stephen Hawking und Unternehmer wie Elon Musk oder Bill Gates davor warnen, dass künstliche Intelligenz eine Bedrohung für die Menschheit darstellt, schlägt das KI-Thema hohe Wellen. Die Stiftung für Effektiven Altruismus (EAS, vormals GBS Schweiz) hat mit der Unterstützung von Experten/innen aus Informatik und KI ein umfassendes Diskussionspapier zu den (...) Chancen und Risiken der künstlichen Intelligenz verfasst und geht darin auf aktuelle, mittel- und langfristige Herausforderungen im Bereich der KI-Entwicklung ein. (shrink)

Introduction: This article discusses the brain hierarchical organization/evolution as a consequence of the information-induced brain development, from the perspective of the Informational Model of Consciousness. Analysis: In the frame of the Informational Model of Consciousness, a detailed info-neural analysis ispresented, concerning the specific properties/functions of the informational system of the human body composed by the Center of Acquisition and Storing of Information, Center of Decision and Command, Info-Emotional Center, Maintenance Informational System, Genetic Transmission System, Info Genetic Generator and Info- Connection (...) center, in relation with the neuro-connected brain areas, with a special attention to the Info-Connection and its specific properties. Besides a meticulous analysis of the info-connections/neuro-functions of these centers, a special attention was paid to limbic/cingulate cortex activities. Defined as a trust/confidence center, additional features are highlighted in correlation with the activity of the anterior cingulate cortex, consisting in the intervention/moderation of amygdala emotional signals, conflicting opposite YES/NO data and error elimination in the favor of the organism adaptation/survival, the intervention in the certainty/uncertainty balance to select a suitable pro-life information (antientropic effect), in moderation of pain and in the stimulation of the empathic inter-human relations/communication. Representing the correspondence between the informational subsystems and the brain area map, itis shown that the up/down integration of information by epigenetic mechanisms and the down/ up evolution are correlated. Results: The analysis of the functions of the anterior cingulate opens new gates of investigations concerning the involved intimate mechanisms at the level of cell microstructure, specifically on the compatibility with quantum assisted processes admitted by the Informational Model of Consciousness and the quantum-based models The discussion on the information integration/codification by epigenetic mechanisms shows that this process starts from the superior levels of brain conscious info-processing areas and progressively advances to the automatic/autonomic inferior levels ofthe informational system, under insistent/repetitive cues/stress conditions, pointing out an hierarchical functional/anatomical structure of the brain organization. Additional arguments are discussed, indicating thatthe down/up progressive scale representation is a suggestive illustration of the brain evolution, induced/assisted/determined by information, accelerated at humans by the antientropic functions of the Info-Connection center. Conclusions: The hierarchical organization of the brain is a consequence of the integration process of information, defining its development accordingly to the adaptation requirements for survival during successive evolution stages of the organism, information playing a determinant/key role. (shrink)

Michelle’s thesis explores the extent to which a researcher could contribute to change by engaging leaders in conversations that might intensify commitment to or the direction of their actions around socio-environmental decline in Bermuda as a country historically organised in the tradition of an entrepreneurial for-profit enterprise. The framing of a space to reflect on highlighted the significance of time that led to the bricolage design of a heuristic device called a moon gate. Time, the keystone of the moon gate, (...) created a prism lighting up the twists and turns of kaleidoscopic images of the chaos of the markets and the creative diversity of human and nonhuman participants. She undertook a philosophical approach with her study of the contested space of time around sensitivity to maintaining a fulcrum point based on the wellbeing of people and planet. (shrink)

In the history of philosophy, the distinction between positive and negative predication has been collapsed. The collapse has caused us to search for a way through Parmenides’ gate: we have constructed scaffolding to see over its boundaries. Kant gave us the distinction between conceptual and non-conceptual knowledge; Hegel gave us determinate negation; Frege gave us the negation stroke; Husserl gave us bracketing and disappointment; G. Spencer-Brown gave us a calculus of distinction. Despite this, we find ourselves—alongside Wittgenstein— wondering how it (...) can be the case that we are able to think what is not the case. We are puzzled by the fact that we can think nothing without the thought lacking content. I suggest that this confusion is unnecessary. Throughout this work, I exercise the thought that the distinction between positive and negative predication is mistaken. I rather suggest that to think what is or is not the case necessarily depends upon an exemplar distinction that is experientially recognized and learned in the world. All the same, our capacity to understand natural distinction likewise depends upon our practical and pervasively conceptual capacities to express it in language. I conclude by suggesting that what makes positive and negative predication distinct is a fundamental unity in conceptual form through its capacity to play distinct functional roles in linguistic practice. (shrink)

At a first level of interpretation Burke's work might be considered a masterpiece of the conservatory ideology, but thanks to its profound reflections about the human nature, the state, history, and society, it becomes an authentic political philosophy. Burkes political philosophy is built on two fundamental conceptual pillars: prejudice and emotional rationality. These pillars ensure a logical and systematic unit to the diverse themes of his writings. The study is going to interpret the Burke’s philosophical contributions in the context of (...) the conservative ideology. By questioning metaphysics through emotional rationality and not trough transcendental criticism, Burke finds a genuine way to establish his political philosophy leaving an open gate for liberty and progress. (shrink)

I claim that the underlying premises of the modern era - e-r-a - are false in a way that carries catastrophic consequences. Despite the many genuine achievements of the modern world—which I for one would not want to live without—the spirit of modernity has been one which denigrated the basic conditions of human being. In the name of freedom and knowledge, the modern era gave birth precisely to the non-empathically responding world, the schizoid ghost in the machine, which now threatens (...) to dissolve both humanity and the natural world. We must find the means to correct the mistaken premises which form the modern error. The time has come to find a new way of renewing reason, a project requiring a transformation of values and outlook as vast as those which took place in the axial age or the modern age. The renewal of reason will involve opening the gates to the entire historical and prehistorical heritage of humankind, to renew the archaic values of family, household, neighborhood and local community and the sympathetic relations they engender, to renew those organic and communicative essences of play, dreaming and mother-infant nurturance which are our human-mammalian legacy and crucial for the development of the spontaneous self, and also making a life-sustaining world culture with self-critical institutions capable of supporting and protecting the vitality of local ways. Without the hope of such a thoroughgoing transformation, we are likely to continue to go the way of the earth’s ozone shield into corrosive self-extinction . (shrink)

Esse artigo busca oferecer um panorama de problemas relativos à existência da psicologia, a partir das questões de sua unidade, especificidade e objetividade. Para isso, analisam-se breves menções a figuras clássicas de sua história (como Wundt, Comte, Watson e Vygotsky), mostrando ambigüidades constitutivas do próprio “nascimento” da psicologia como disciplina “una” e “científica”. Ao perguntar sobre as razões da dispersão da psicologia, seu estatuto ambíguo e seu objeto “complexo”, abrimos no final o problema de que, mais do que resolver internamente (...) uma ambigüidade constituinte, é propriamente fora da ciência ou dos procedimentos ditos “tradicionais” de história da psicologia, que as condições de surgimento dessas ambigüidades – e da própria psicologia enquanto “ciência humana” – podem ser evidenciadas. Daí o apontamento conclusivo que sugere a importância de uma visita rigorosa às análises da modernidade empreendidas por Michel Foucault, para além dos portões das perspectivas históricas e epistemológicas. /////////////////// This article aims to provide a panorama of problems relating to the existence of psychology, based on issues of its unity, specificity and objectivity. To this objective, analysis is made of brief references to classic figures of its history (such as Wundt, Comte, Watson and Vygotsky), showing constituent ambiguities in the very “birth” of psychology as a “specific” and “scientific” discipline. Raising the question of why is psychology disperse, has ambiguous statutes, and is a “complex” matter, we suggest at the end (without reaching a conclusion) that, more than resolving internally a constituent ambiguity, it is really outside of science or the so-called “traditional” procedures of history of psychology, that the condition in which these ambiguities arose – and that of psychology itself as a "human science” – can be witnessed. Hence the conclusive indication that suggests the importance of a rigorous visit to the analyses of modernity undertaken by Michel Foucault, beyond the gates of the historical and epistemological perspectives. (shrink)

This paper investigates the question whether we could have reason to believe that time is two-dimensional. I connect discussion of this question to discussion of the question whether we could have reason to believe that there has been a global time freeze.

The discussion of ethics, corporate responsibility and its educational dimensions focuses primarily on CSR, corporate citizenship and philanthropic theory and practise. The partnership between Microsoft Corporation and UNHCR was launched to help the victims of the Kosovo crisis, at the same time as the Bill and Melinda Gates Foundation gained momentum, and in particular, at the same time as Microsoft experienced a decrease in stock value. This case study sheds light on a decade of Microsoft Corp. efforts to align (...) business objectives with refugee aid, by use of corporate expertise and company revenues. As a leader in technology and corporate citizenship, can Microsoft bridge the digital divide for the disadvantaged and arouse the unlimited potential of tomorrow’s leaders, as the company claims in its communications? Is the partnership beneficial to UNHCR, in line with corporate objectives of “doing big things” and “doing good”? (shrink)

The objective of theatre establishments as business concerns remains predominantly to cover costs and make profits. Of all the avenues generation, gate-takings remain readily available and have been used by theatres for centuries now. But due to fraudulent activities, theatre establishments can be short-changed. Consequently, revenues can be lost and the establishments unable to meet their obligations; taxes, honoraria, rents, wages etc. it is therefore imperative to adopt measures that would strengthen gate-takings as revenue machinery, devoid of fraudulent practices. This (...) work examines theatre as a business and prescribes measures that can be adopted to safe-guard gate-takings, as part of internal financial control in theatre establishments. (shrink)

Reason or logic is elementary thought elucidated and emphasized in holly Quran and Hadith. Every idea in the interpreted verses of Quran and Hadith has logical aspect to describe it. Senses are the gate ways of knowing and reason is the hub of interpretation and organization. We can say that senses only collect data and reason interprets it. Logic is derived from the Greek word “Logos” which means “Art of reasoning”. Reasoning is of three kind: inductive (from particular to general), (...) deductive (from general to particular) and abductive reasoning (from observation to hypothesis). In this research paper I will explain the philosophical teachings of holly Quran and Hadith and also the philosophical problems which got birth from the interpretation of the texts. Reason is the faculty of mind which helps us to understand both the categorical verses and the metaphorical verses. Quran is the uncreated word of God and Hadith is the saying and doings of the Prophet Muhammad (S. A.W). (shrink)

Background: Health care practitioners are recognized to have a large influence in shaping uptake of vaccine in new borns, children, adolescents, as well as adults. Parents remain more secure in their decisions when health care practitioners communicate successfully with them about vaccine dangers and benefits, the value as well as necessity for vaccinations, as well as vaccine safety. Thus, immunization remain the foundation of the primary health care system, an indisputable human right as well as a global health and development (...) success story, saving millions of lives yearly. Recently, we have vaccines to prevent more than 20 life threatening diseases, helping people of all ages live longer, healthier lives. Yet despite tremendous progress, far too many people around the world, including nearly 20 million infants yearly have insufficient access to vaccines. In some countries, progress has stalled or even reversed, and there is a real risk that complacency will undermine past achievements. Purpose: The current study aimed to explores vaccine hesitancy, its barriers and impact studies regarding COVID-19 decision impacts. Also, to provides policy and decision makers and operational staff with evidence to inform decisions to promote vaccine uptake across Bayelsa State. Methods: A literature review tried to do a deep dive by using a variety of search engines such as Scopus, Research Gate, Mendeley, Summon, PubMed, Google Scholar, Hinari, Dimension, Academia, CAB Abstract, OARE Abstract, SSRN search strategy to retrieve research publications, “grey literature” and expert working group reports, including author’s field experience. Findings: Absence of uniform methods of organization in the various health care facilities upon which we were obliged to rely. Thus affecting the overall immunization programme and health system. Hence policy must urgently address these challenges with emphasis on policy clarity while continuously improving infrastructure. Conclusions: Bayelsa State is categorized as low/poor performing as the findings suggest that the involvement of community-based leaders can improve community participation and acceptance while enhancing and strengthening integrated disease surveillance and Adverse Events Following Immunization (AEFI) monitoring and reporting systems; and conducting integrated advocacy and communications activities to promote demand for vaccination as part of increasing overall demand and acceptability of all essential Primary Health Centers (PHC) services, thus, breaking barriers of vaccine hesitancy. (shrink)

Nos meses de Junho/Julho - 2019, houve relatos de vazamento de patógenos do Fort Detrick, instalação do Comando Médico do Exército dos EUA, conhecido por desenvolver armas biológicas e que abriga um dos muitos laboratórios BSL-4 do país. Em agosto de 2019, a instalação foi fechada para investigação e a imprensa não teve acesso a informações detalhadas. -/- Em setembro de 2019, um vírus mortal começou a se espalhar nos EUA infectando 26 milhões de pessoas naquele outono, com pelo menos (...) 250.000 hospitalizadas e 20.000 mortes. Posteriormente o Dr. Robert Redfield, diretor do Centro de Controle e Prevenção de Doenças dos EUA, reconheceu perante o Comitê do Congresso, que algumas mortes por influenza foram mais tarde diagnosticadas como de Covid-19. -/- Em 18 de outubro de 2019, dia do início dos Jogos Mundiais Militares em Wuhan, que contou com a presença de militares americanos, a Fundação Bill & Melinda Gates e o Johns Hopkins Center for Health Security em parceria com o Fórum Econômico Mundial, promovem uma simulação de pandemia de coronavírus em Nova York, reunindo líderes empresariais e agentes do governo. -/- Em novembro de 2019, o prefeito de Belleville, Nova Jersey, Michael Melham, passou mal e seu diagnóstico foi uma grave pneumonia posteriormente confirmado como sendo Covid-19. Falei com Michael sobre a veracidade dos fatos e ele me confirmou o diagnóstico. Disse que possui dois testes de anticorpos positivos para a Covid-19. -/- Em janeiro de 2019 a revista Science publicou um artigo questionando a teoria oficial de que o vírus havia sido transmitido de um animal para um ser humano no mercado de Wuhan e outro estudo publicado na revista The Lancet, concluiu que 13 das primeiras 41 pessoas diagnosticadas com Covid-19 não tiveram nenhum contato com o mercado de Wuhan, além disso, o Dr. Daniel Lucey, professor de doenças infecciosas da Georgetown University Medical Center, disse baseado em evidências, que o "paciente zero", foi infectado antes de dezembro de 2019, mais precisamente entre outubro e início de novembro de 2019, mas o diagnóstico era de pneumonia e assim o vírus começou a se espalhar por Wuhan. -/- Agora, não é porque o novo coronavírus surgiu na China, que sua origem seja o laboratório de Wuhan, a gripe espanhola por exemplo, se disseminou no mundo a partir da Europa matando 50 milhões de pessoas e sua origem estava no Fort Riley, em Kansas, EUA. (shrink)