Resumo A transferência de embriões em bovinos tem o objetivo principal de aprimorar o melhoramento genético e otimizar a reprodução bovina A importância dessa prática é destacada pela sua contribuição para a maximização de características desejadas nos rebanhos, como qualidade de carne, eficiência reprodutiva e resistência a condições ambientais adversas. Este trabalho descreve e analisa as técnicas avançadas utilizadas nesse processo, incluindo seleção genômica, sexagem de embriões, produção in vitro, protocolos não cirúrgicos, sincronização reprodutiva, criopreservação de embriões e uso de (...) marcadores de fertilidade. A compreensão aprofundada dessas técnicas é fundamental para o sucesso da transferência de embriões, bem como para a capacidade de personalizar e aprimorar as características específicas dos rebanhos. Enfatizando a importância da expertise de profissionais especializados em reprodução bovina, este trabalho busca oferecer uma visão abrangente das práticas atuais e avanços tecnológicos nesse campo. Ao unir ciência e prática, torna-se importante a comparação de técnicas, bem como relacionar resultados eficientes para promover qualidade genética, trazer a sustentabilidade e envolver a técnica em um cenário atualizado da indústria. Palavras-chave: Embriões; Hormônio; Reprodutor. -/- Abstract Embryo transfer into cattle has the main objective of improving genetic improvement and optimizing bovine reproduction. The importance of this practice is highlighted by its contribution to maximizing desired characteristics in herds, such as meat quality, reproductive efficiency and resistance to environmental conditions adverse. This work describes and analyzes the advanced techniques used in this process, including genomic selection, embryo sexing, in vitro production, non-surgical protocols, reproductive synchronization, embryo cryopreservation and the use of fertility markers. An in-depth understanding of these techniques is critical to the success of embryo transfer, as well as the ability to customize and enhance specific herd characteristics. Emphasizing the importance of the expertise of professionals specialized in bovine reproduction, this work seeks to offer a comprehensive view of current practices and technological advances in this field. When combining science and practice, it becomes important to compare techniques, as well as relate efficient results to promote genetic quality, bring sustainability and involve the technique in an updated industry scenario. Keywords: Embryos; Hormone; Reproducer. -/- REFERÊNCIAS BIBLIOGRÁFICAS ABIEC. Associação Brasileira das Indústrias Exportadoras de Carnes. 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S.; CATUSSI, B. L. C.; ABREU, L. A.; ELLIFF, F. M.; SILVA, L. G.; BATISTA, E. S.; CREPALDI, G. A. Evolução e perspectivas da Inseminação Artificial em bovinos. Revista Brasileira de Reprodução Animal, v.43, n.2, p.308-314, 2019. 13 BARUSELLI, P. S. IATF gera ganhos que superam R$ 3,5 bilhões nas cadeias de produção de carne e de leite. Boletim Eletrônico do Departamento de Reprodução Animal/FMVZ/USP, 2.ed., v.8, n.8, p.7, 2019. BINELLI, M. Anti-luteolytic to improve in cattle. Acta Scientiae Veterinariae. v.9, p.8, 2001. BÓ, G. A. Manipulação hormonal do ciclo estral em doadoras e receptoras de embrião bovino. Acta Scientiae Veterinariae. v.9, p.7, 2004. BÓ, G.; MAPLETOFT, R. Evaluation and of bovine. Animal Reproduction. v.8, p.9, 2013. BUSS, V. Efeito da dose e momento da administração de eCG em protocolos de IATF aplicados e vacas de corte em anestro. Universidade Federal do Pampa, Dissertação – Programa de Pós-Graduação em Ciência Animal, v.8, n.8, p.9, 2020. Centro de Estudos Avançados em Economia Aplicada (CEPEA). Boletim do leite. São Paulo, Ano 25, n.286, 2019. CHAVES, D. F.; ALVES, M. J. Protocolo de receptoras de embriões: índices de aproveitamento de corpo lúteo e taxa de prenhez. Animal Reproduction. v.9, p.7, 2023. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia Clínica do Ciclo Estral de Vacas Leiteiras: Desenvolvimento Folicular, Corpo Lúteo e Etapas do Estro. 2020. DA SILVA, Emanuel Isaque Cordeiro. Transferência de Embriões nos Animais e a Indústria de Embriões no Brasil. 2020. DALCIN, L.; LUCCI, C. M. Criopreservação de embriões de animais de produção: princípios criobiológicos e estado atual. Rev. Bras. Reprod. Anim. v.7, p.7, 2010. DANTAS, K. S. A. Seleção de receptoras em um programa de transferência de embriões (PIVE) em bovinos no nordeste do Brasil. Ciência Animal. v.9, p.7, 2018. D’AVILA, C. A.; MORAES, F. P.; LUCIA J. R. T.; GASPERIN, B. G. Hormônios utilizados na indução da ovulação em bovinos – Artigo de revisão. Revista Brasileira de Reprodução Animal, v.43, n.4, p.797-802, 2019. DEMÉTRIO, D. G. B. Colheita e transferência de embriões bovinos. Dissertação (Mestrado em Reprodução Animal) – Faculdade de Medicina Veterinária e Zootecnia da UNESP, Campus de Botucatu, São Paulo. v.9, p.76, 2003. FAO – Organização das Nações Unidas para a Alimentação e Agricultura. O Estado da Insegurança Alimentar e Nutrição no Mundo (SOFI) 2021. Faculdade de Medicina Veterinária e Zootecnia da UNESP. v.4, n.6, p.6, 2021. FILHO, L. C. C. Fatores que interferem na eficiência reprodutiva de receptoras de embrião bovino. Arq. Ciênc. Vet. Zool. v.7, p.9, 2013. GONZÁLEZ, F. H. D. Introdução a Endocrinologia Reprodutiva Veterinária. UFRGS. v.9, p.7, 2002. GOODHAND, K. In vivo recovery and vitro embryo from bovine aspirated at frequencies or FSH treatment. Animal Reproduction. v.8, p.87, 1999. 14 HAFEZ, E. S. E.; HAFEZ, B. Reprodução animal. 7ed. Barueri: Manole. v.7, p.7, 2004. HONORATO, M.T. Importância da escolha de receptoras em um programa de transferência de embriões em bovinos. Barueri: Manole. v.8, p.6, 2013. HOPPER, R. Bovine Reproduction. Blackwell. v.8, p.8, 2015. IBGE. Instituto Brasileiro de Geografia e Estatística. Pesquisa da Pecuária Municipal 2021 (PPM 2021). IBGE. v.9, n.7, p.7, 2021. KONIG, H. E.; LIEBICH, H. G. Anatomia dos animais domésticos: texto e atlas colorido. Vol.2. Porto Alegre: Artmed, v.2, p.4, 2004. MARTINS, F. S. Fatores reguladores da foliculogênese em mamíferos. Rev Bras Reprod Anim. v.3, p.9, 2008. MELLO, R. R. C. Desenvolvimento folicular inicial em bovinos. Rev. Bras. Reprod. Anim. v.8, p.9, 2013. OLIVEIRA, A. F. M. Principais hormônios que controlam o comportamento reprodutivo e social das fêmeas ruminantes – Revisão. Rev. Bras. Reprod. v.9, p.8, 2014. OLIVEIRA, C. S. Biotécnicas da Reprodução em Bovinos. EMBRAPA, v.8, p.8, 2014. PASA, C. Transferência de embriões em bovinos. Biodiversidade. v.9, p.9, 2008. PENITENTE FILHO, J. M. Produção de embriões bovinos in vivo e in vitro. Revista CFMV, Ano XX. v.8, p.8, 2014. PHILLIPS, P. E.; JAHNKE, M. M. Embryo Transfer (Techniques, Dono rs, and Recipients). Vet Clin Food Anim, v.9, p.8, 2016. RODRIGUES, J.; BERTOLINI, M. Biotecnologias da reprodução animal: de Aristóteles à edição gênica. Rev. Bras. Reprod. Anim. v.8, p.7, 2019. SANTOS, K. J. G. Biotecnologias reprodutivas e fisiologia reprodutiva da fêmea bovina – conhecimento para o sucesso. Rev. Bras. Reprod. Anim. v.8, p.98. 2012. SANTOS, P. H. Impactos da superestimulação ovariana sobre a diferenciação das células da granulosa bovina. Dissertação de Mestrado em Farmacologia e Biotecnologia – UNESP, v.8, p.8. 2017. SILVA, P. R. B. Regulação farmacológica do ciclo estral de bovinos. UNESP. v.9, p.8. 2011. (shrink)

In 1969 Harry Frankfurt published his hugely influential paper 'Alternate Possibilities and Moral Responsibility' in which he claimed to present a counterexample to the so-called 'Principle of Alternate Possibilities' ('a person is morally responsible for what he has done only if he could have done otherwise'). The success of Frankfurt-style cases as counterexamples to the Principle has been much debated since. I present an objection to these cases that, in questioning their conceptual cogency, undercuts many of those debates. Such cases (...) all require a counterfactual mechanism that could cause an agent to perform an action that he cannot avoid performing. I argue that, given our concept of what it is for someone to act, this requirement is inconsistent. Frankfurt-style alleged counterexamples are cases where an agent is morally responsible for an action he performs even though, the claim goes, he could not have avoided performing that action. However, it has recently been argued, e.g. by John Fischer, that a counterexample to the Principle could be a 'Fischer-style case', i.e. a case where the agent can either perform the action or do nothing else. I argue that, although Fischer-style cases do not share the conceptual flaw common to all Frankfurt-style cases, they also fail as counterexamples to the Principle. The paper finishes with a brief discussion of the significance of the Principle of Alternate Possibilities. (shrink)

Reasons can play a variety of roles in a variety of contexts. For instance, reasons can motivate and guide us in our actions (and omissions), in the sense that we often act in the light of reasons. And reasons can be grounds for beliefs, desires and emotions and can be used to evaluate, and sometimes to justify, all these. In addition, reasons are used in explanations: both in explanations of human actions, beliefs, desires, emotions, etc., and in explanations of a (...) wide range of phenomena involving all sorts of animate and inanimate substances. This diversity has encouraged the thought that the term 'reason' is ambiguous or has different senses in different contexts. Moreover, this view often goes hand in hand with the claim that reasons of these different kinds belong to different ontological categories: to facts (or something similar) in the case of normative/justifying reasons, and to mental states in the case of motivating/explanatory reasons. In this paper I shall explore some of the main roles that reasons play and, on that basis, I shall offer a classification of kinds of reasons. As will become clear, my classification of reasons is at odds with much of the literature in several respects: first, because of my views about how we should understand the claim that reasons are classified into different kinds; second, because of the kinds into which I think reasons should be classified; and, finally, because of the consequences I think this view has for the ontology of reasons. (shrink)

In this paper I propose a way of characterizing human agency in terms of the concept of a two‐way power. I outline this conception of agency, defend it against some objections, and briefly indicate how it relates to free agency and to moral praise‐ and blameworthiness.

Two conceptions of motivating reasons, i.e. the reasons for which we act, can be found in the literature: (1) the dominant 'psychological conception', which says that motivating reasons are an agent's believing something; and (2) the 'non-psychological' conception, the minority view, which says that they are what the agent believes, i.e. his beliefs. In this paper I outline a version of the minority view, and defend it against what have been thought to be insuperable difficulties - in particular, difficulties concerning (...) 'error cases' (cases where what the agent believes is false); and difficulties concerning the explanation of action. Concerning error cases, I argue that if we are motivated by something believed that is true, what motivates us to act is a motivating reason. By contrast, if we are motivated by something believed that is false, then what motivates us to act is merely an apparent motivating reason. Either way, what motivates us is, as the non-psychological conception says, what we believe and not our believing it. I offer an account of the relation between motivating reasons and the explanation of action, and argue that this account helps bring out two important points. One is that the fact that we often do, and indeed sometimes must, use explanations such as 'He did it because he believed that p' does not vindicate the psychological conception of motivating reasons. The other is that endorsing the non-psychological conception of motivating reasons does not commit one to a non-factive view of explanations of action. (shrink)

This paper seeks a better understanding of the elements of practical reasoning: premises and conclusion. It argues that the premises of practical reasoning do not normally include statements such as ‘I want to ϕ’; that the reasoning in practical reasoning is the same as in theoretical reasoning and that what makes it practical is, first, that the point of the relevant reasoning is given by the goal that the reasoner seeks to realize by means of that reasoning and the subsequent (...) action; second, that the premises of such reasoning show the goodness of the action to be undertaken; third, that the conclusions of such reasoning may be actions or decisions, that can be accompanied by expressions of intention, either in action, or for the future; and that these are justified, and might be contradicted, in ways that are not only peculiar to them (i.e. in ways that diverge from those found in theoretical reasoning), but are distinctively practical, in that they involve reference to reasons for acting and to expressions of intention, respectively.1. (shrink)

Ignorance is often a perfectly good excuse. There are interesting debates about whether non-culpable factual ignorance and mistake subvert obligation, but little disagreement about whether non-culpable factual ignorance and mistake exculpate. What about agents who have all the relevant facts in view but fail to meet their obligations because they do not have the right moral beliefs? If their ignorance of their obligations derives from mistaken moral beliefs or from ignorance of the moral significance of the facts they have in (...) view, should they be excused for failing to meet their moral obligations? It is not obvious that they should. In this paper we argue that the best non-skeptical accounts of moral responsibility acknowledge that factual ignorance and mistake will diminish moral responsibility in a way that moral ignorance and mistake will not. That is because factual ignorance is often non-culpable so long as it meets certain merely procedural epistemic standards but the same is not true of moral ignorance. Our argument is that the assumption that it is gets the standards of culpability for moral ignorance wrong, and that the mistake is encouraged by the thought that culpability in general requires an instance of known wrongdoing: that acting wrongly requires de dicto unresponsiveness to one’s obligations at some stage. We deny this and conclude that, therefore, ignorance and mistaken belief are indeed often perfectly good excuses – but far less often than some philosophers claim. (shrink)

Conservatism about perceptual justification tells us that we cannot have perceptual justification to believe p unless we also have justification to believe that perceptual experiences are reliable. There are many ways to maintain this thesis, ways that have not been sufficiently appreciated. Most of these ways lead to at least one of two problems. The first is an over-intellectualization problem, whereas the second problem concerns the satisfaction of the epistemic basing requirement on justified belief. I argue that there is at (...) least one Conservative view that survives both difficulties, a view which has the further ability to undercut a crucial consideration that has supported Dogmatist views about perceptual justification. The final section explores a tension between Conservatism and the prospects of having a completely general account of propositional justification. Ironically, the problem is that Conservatives seem committed to making the acquisition of propositional justification too easy. My partial defense of Conservatism concludes by suggesting possible solutions to this problem. (shrink)

The special composition question asks, roughly, under what conditions composition occurs. The common sense view is that composition only occurs among some things and that all and only ‘ordinary objects’ exist. Peter van Inwagen has marshaled a devastating argument against this view. The common sense view appears to commit one to giving what van Inwagen calls a ‘series-style answer’ to the special composition question, but van Inwagen argues that series-style answers are impossible because they are inconsistent with the transitivity of (...) parthood. In what follows I answer this objection in addition to other, less troubling objections raised by van Inwagen. (shrink)

An argument is epistemically self-defeating when either the truth of an argument’s conclusion or belief in an argument’s conclusion defeats one’s justification to believe at least one of that argument’s premises. Some extant defenses of the evidentiary value of intuition have invoked considerations of epistemic self-defeat in their defense. I argue that there is one kind of argument against intuition, an unreliability argument, which, even if epistemically self-defeating, can still imply that we are not justified in thinking intuition has evidentiary (...) value. (shrink)

This essay is about the loss of voice. It is about the ways in which the act of writing philosophy often results in an alienating and existentially meaningless experience for many budding philosophers, particularly those who wish to think from their racialized and gendered identities in professional academic philosophy.

Do factive mental states come in degrees? If so, what is their underlying structure, and what is their theoretical significance? Many have observed that ‘knows that’ is not a gradable verb and have taken this to be strong evidence that propositional knowledge does not come in degrees. This paper demonstrates that the adjective ‘aware that’ passes all the standard tests of gradability, and thus strongly motivates the idea that it refers to a factive mental state that comes in degrees. We (...) will explore a range of structural questions that have been overlooked in regard to our awareness of facts, showing that the degreed structure of awareness has significant implications for our understanding of knowledge. (shrink)

In this article I argue that characterizations of anger as a hostile emotion may be mistaken. My project is empirically informed and is partly descriptive, partly diagnostic. It is descriptive in that I am concerned with what anger is, and how it tends to manifest, rather than with what anger should be or how moral anger is manifested. The orthodox view on anger takes it to be, descriptively, an emotion that aims for retribution. This view fits well with anger being (...) a hostile emotion, as retribution is punitive. I will argue that a different view of anger deserves our attention. On this alternative view, anger aims for recognition of harms done, rather than for the punishment of those who have committed them. I argue that we have reason to favour a strong view that excludes retribution from anger’s main aims. In addition, I offer a diagnosis of the reasons that led the retributive view of anger to become, and remain, orthodoxy. This diagnosis provides indirect reason to give my descriptive proposal serious consideration, for it highlights that the orthodox view has dominated folk and philosophical conceptions of anger for reasons that do not speak in favour of the view’s veracity. The view that anger is a hostile emotion will therefore emerge as in need of serious scrutiny. (shrink)

This work introduces the reader to the central issues and theories in Western environmental ethics, and against this background develops a Buddhist environmental philosophy and ethics. Drawing material from original sources, there is a lucid exposition of Buddhist environmentalism, its ethics, economics and Buddhist perspectives for environmental education. The work is focused on a diagnosis of the contemporary environmental crisis and a Buddhist contribution for positive solutions. Replete with stories and illustrations from original Buddhist sources, it is both informative and (...) engaging. (shrink)

Since the famous passage in which Socrates (Plato 38a5-6) says that the unexamined, and therefore non-reflected, life is not worth living, “reflection” has been a diffuse and iterant term in ethics, moral philosophy, epistemology, political philosophy (Tiberius 2008; Skorupski 2010), but also in psychology (Marsico, Andrisano Ruggieri & Salvatore 2015). This chapter outlines the discussion of reflection and presents the book "Thinking about Onself", a volume that opens a new perspective on the topic of reflection, considering the most recent approaches (...) in both philosophy (namely in epistemology ) and cultural psychology. (shrink)

The phenomenon of self-anger has been overlooked in the contemporary literature on emotion. This is a failing we should seek to remedy. In this paper I provide the first ef-fort towards a philosophical characterization of self-anger. I argue that self-anger is a genuine instance of anger and that, as such, it is importantly distinct from the negative self-directed emotions of guilt and shame. Doing so will uncover a potentially distinctive role for self-anger in our moral psychology, as one of the (...) strongest affective motiva-tors for self-change. (shrink)

Se plantea el problema de la existencia de una campo científico -el geográfico - para el cual existen candidaturas e disciplinas determinadas como la Geografía Física, La Humana, la R egional y la Universal, etc. Se plantea la diferencia entre ciencias naturales y humanas, así como entre ciencias texonómicas y ciencias mereológicas, como marcos de análisis para las ciencias geográficas.

The basing demand on doxastic justification is a widely held and highly intuitive dogma of contemporary epistemology. In Silva [2015, AJP], I argued that the dialectical significance of this dogma is severely limited by our lack of independent grounds for endorsing it. Oliveira [2015, AJP] sought to defend the basing demand on doxastic justification. Here I explain why Oliveira’s attempted defense of the basing demand misses its mark. I also briefly suggest that there is an alternative way of defending (...) the basing demand. The alternative way is reconciliatory: it shows that most epistemologists may have been right to insist on such a demand, but perhaps still wrong to treat it as a dialectically powerful tool in the assessment of certain substantive epistemological theories. (shrink)

Developments in truthmaker semantics for the most part stay clear of the metaphysical issue of what sort of entities serve as the truthmakers and falsitymakers for sentences. It is assumed that perhaps facts or states of affairs (Fine, 2017a; Jago, 2020), with these taken sometimes as concrete particulars (Hawke, 2018) could serve for the job, but nonetheless that some such entities would do. In this paper I take a closer look at the issue of what entities could or could not (...) play the role of truthmakers and falsitymakers in standard truthmaker semantics (Fine, 2016, 2017a,b; Fine and Jago, 2019), based on desiderata imposed by metaphysical and semantic considerations. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE AS ALTERAÇÕES DO CORPO LÚTEO EM VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__7. ALTERAÇÕES DO CORPO LÚTEO -/- A estrutura funcional desenvolve-se a partir da cavidade folicular após a ovulação. O corpo lúteo é constituído pelas células da teca interna (pequenas e ativas na primeira fase do seu desenvolvimento) e células da granulosa (grandes e ativas na segunda metade do (...) seu desenvolvimento). As principais características de cada tipo de célula podem resumir-se da seguinte forma: As células pequenas são mais sensíveis à ação da LH porque possui uma quantidade maior de receptores biologicamente ativos para esta hormona e a resposta é mediada pelo sistema AMPc-adelinato ciclase. As grandes células lúteas têm menos receptores para a LH (a maior quantidade são para a PGF2α e a PGE2), e são as responsáveis pela produção da oxitocina luteal (BAH, et al. 2006; CAMPO, 2003). Contrariamente às pequenas células lúteas, a produção de progesterona (P4) é parcialmente controlada pelo sistema Ca+2 - Fosfatil inositol-quinase C (CAMPO, 2003). A regulação da função do corpo lúteo é um mecanismo complexo. Nela intervêm fatores tróficos e líticos que estão presentes em forma simultânea durante todo o ciclo estral, e portanto a estimulação ou inibição da síntese e secreção de P4 depende do balanço entre estes fatores. (CAMPO, 2003). Dentro dos fatores tróficos, os nutrientes desempenham um papel relevante sobre a luteólise e as funções luteotrópicas, entre estas pode-se citar a ação das seguintes: -/- 7.1 Vitaminas Deficiência em betacarotenos. Vitamina A é um termo genérico que designa qualquer composto com atividade de retinol, o trans-retinol, é o composto base, sua forma aldeído e ácido são chamados de retinol e ácido retinóico, respectivamente. Por outro lado, a forma ativa da Vitamina A participa no mecanismo da visão, como 11-cis-retinal. Adicionalmente, o betacaroteno, considerado uma provitamina A é a única forma em que esta encontra nas plantas. Em sentido nutricional, a família da Vitamina A compreende todos os compostos que possuem atividade de retinol, incluindo cerca de cinquenta carotenoides que possuem atividade de provitamina A, aceitando-se que o mais ativo é o trans-betacaroteno (TORRES, et al. 2002). As vitaminas que são necessárias para o crescimento e a produção, também são essenciais para a reprodução. As recomendações atuais de vitamina A são de 75.000 UI/dia durante a lactação e 80.000 UI/dia (nota: 1 mg de Vitamina A = 400 UI) durante o período seco nas vacas leiteiras. A suplementação com vitamina A tem pouco risco de toxicidade, enquanto a sua deficiência pode retardar o aparecimento do primeiro cio/estro, induzir cios/estros silenciosos, aumentar o número de quistos ováricos, reduzir os índices de concepção, causar abortos, mortes embrionárias e ocasionar o nascimento de bezerros debilitados e fracos, uma vez que não irão nascer com os índices e requerimentos ideais de nutrientes passados da mãe para o feto pela placenta, e que, já que a mãe possui deficiência nutricional, o colostro não terá o efeito completo para passar a imunidade essencial ao neonato. Embora os mecanismos de ação não sejam claros, foram notificadas maiores secreções de esteroides ováricos quando as concentrações de β-carotenos no fluido folicular foram elevadas; logo, foram observadas maiores concentrações elevadas de β- estradiol e vitamina A nos folículos que terminaram em ovulação do que naqueles que terminaram em atresia. Para evitar as perdas reprodutivas por deficiência de vitamina A, pode-se optar pela administração oral ou injetável desta ao animal, mediante dois métodos: o primeiro consiste em adicionar 1 a 2,5 kg de premix vitamínico em 1 tonelada de grãos o que supre de 4 a 6.000 UI o que é desejável; o segundo é a administração via injetável em quantidades vide bula do fármaco. 7.2 Minerais O excesso de fósforo é absorvido principalmente no intestino delgado dos mamíferos através de um mecanismo de transporte ativo dependente do sódio, que é estimulado pela pró-hormona 1,25- hidroxivitamina D3. Os ruminantes são capazes de absorver o fósforo dietético em proporção direta às quantidades presentes na ração. Estima-se que aproximadamente 1% do corpo animal é composto de fósforo, do qual 85% está presente nos dentes e no tecido ósseo. Os tecidos moles são capazes de conter entre 0,15-0,20% de fósforo sob a forma de fosfoproteínas, nucleoproteínas, fosfolipídios, fosfato creatinina, adenosintrifosfato, glicose-6-fosfato, etc. Ao nível do plasma sanguíneo, o fósforo apresenta valores de 12,09 mg/dl. Os valores plasmáticos de fósforo são regulados principalmente pelo rim, sendo observado um aumento na excreção urinária do elemento inorgânico quando este excede a capacidade de transporte (REBOLLAR & MATEOS, 1999). O fósforo faz parte dos fosfolipídios, que são importantes no transporte de lipídios e seu metabolismo, como componente das membranas celulares. O fosfato faz parte do RNA e do DNA, componentes celulares vitais, e são essenciais para a síntese proteica. O fosfato faz parte de sistemas enzimáticos como a cocarboxilase e NAD, portanto está envolvido em todos os processos de síntese e regulação energética, dado que o corpo lúteo requer altas quantidades de energia para a síntese celular e hormonal, um excesso de fósforo pode bloquear a capacidade renal da sua regulação gerando um desequilíbrio catiônico que descompensa a relação Na:K, já que deverão ser excretados íons fosfato para regular o equilíbrio ácido-básico, desta forma, os processos celulares em tecidos de alta sensibilidade como o ovário serão afetados em sua função. A situação para prevenção de problemas relacionados ao fósforo (P) já foi tratada em assuntos anteriores, porém, sempre vale frisar para o leitor fiel que me lê que as exigências de P presentes na matéria seca (MS) variam entre 0,17 e 0,59% de P por kg/MS para bovinos de corte e em 0,32 a 0,44% por kg/MS para o gado leiteiro. Dessa forma, dados obtidos por pesquisas, ditam que para a mantença de uma vaca ou quaisquer outra categoria bovina o ideal é o consumo de 1.43 g/100 kg de peso vivo (PV), garantindo assim a prevenção de possíveis afecções reprodutivas como as alterações do corpo lúteo. Gramíneas, forragens, leguminosas e os concentrados fornecem muito bem os requerimentos de fósforo para os animais, todavia deve-se estar atento as relações e dependências do P com outros elementos como o Ca e a relação Na:K (10-15:1 idealmente). 7.3 Compostos estrogênicos Os fitoestrogênios afetam repetidamente a estabilidade do corpo lúteo. Os compostos estrogênicos encontrados principalmente em leguminosas pertencem principalmente a três grupos: isoflavanos, isoflavonas, presentes no gênero Trifolium e praticamente restritos às leguminosas, e cumestanos, que foram estudados na alfafa (Medicago sativa) e na Melilotus alba. Todas as isoflavonas sofrem algum grau de transformação no rúmen, sendo o Isoflavonoide formononetina, na realidade um pró-estrógeno, o único que se ativa no ecossistema ruminal ao ser convertido em equol, enquanto que as demais são degradadas a produtos inativos (RAMOS, et al. 1998). Por fim, a alta concentração no sangue do equol retarda a retroalimentação sobre a hipófise mediante a qual se reduzem os níveis de FSH para dar lugar à onda ovulatória de LH, se esta não ocorrer, o corpo lúteo obviamente não se formará. O conhecimento acerca dos estrogênios na alimentação animal é defasado nos livros sobre o tema, no entanto, o criador pode ficar tranquilo no que tange o tema na prática da sua fazenda e dos seus animais, uma vez que tal elemento é muito bem fornecido naturalmente por meio dos alimentos volumosos presentes no seu pasto. -/- Apoio -/- Realização -/- REFERÊNCIAS BIBLIOGRÁFICAS BAH, Mamadou M. et al. Role of intraluteal prostaglandin F2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins & other lipid mediators, v. 79, n. 3-4, p. 218-229, 2006. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. CAMPO, E. Comportamiento reproductivo del ganado Bovino y Bufalino. 2003. Universidad Agraria de la Habana. Havana, 2003. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. HURLEY, W. L.; DOANE, R. M. Recent developments in the roles of vitamins and minerals in reproduction. Journal of Dairy Science, v. 72, n. 3, p. 784-804, 1989. KUMAR, Sudhir et al. Importance of micro minerals in reproductive performance of livestock. Veterinary world, v. 4, n. 5, p. 230, 2011. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. RAMOS, Graciano et al. Los compuestos secundarios de las plantas en la nutrición de los herbívoros. Archivos de Zootecnia. 47: 597-620, 1998. REBOLLAR, Paloma García; MATEOS, Gonzalo González. El fósforo en nutrición animal. Necesidades, valoración de materias primas y mejora de la disponibilidad. CURSO DE ESPECIALIZACIÓN FEDNA. Avances en nutrición y alimentaciín animal, XV, p. 19-64, 1999. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. TEIXEIRA, J. C. Nutrição de ruminantes. Lavras: FAEPE, 1992. TORRES, M. et al. Aspectos Farmacológicos relevantes de las Vitaminas Antioxidantes (E, A y C). Archivos Venezolanos de Farmacología y Terapéutica, v. 21, n. 1, p. 22-27, 2002. YASOTHAI, R. Importance of minerals on reproduction in dairy cattle. International Journal of Science, Environment and Technology, v. 3, n. 6, p. 2051-2057, 2014. -/- Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020. (shrink)

This essay explores the intersection of racism, racial embodiment theory and the recent hostility aimed at immigrants and foreigners in the United States, especially the targeting of people of Latin American descent and Latino/as. Anti-immigrant and anti-foreigner sentiment is racist. It is the embodiment of racial privilege for those who wield it and the materiality of racial difference for those it is used against. This manifestation of racial privilege and difference rests upon a redrawing of the color line that is (...) meant towards preserving exclusive categories of political membership. The charge of racism, however, is elided by the fact that this hostility takes the form of a specious embracement of law and lawfulness. “Illegal” in this sense not only captures the actions of those who enter the United States through clandestine or informal means, but, in light of the history of immigration and citizen- ship law, the term operates as a racial trope that designates non-white status, thus marginalizing and alienating certain immigrants from ongoing nation-formation processes. I explain the source for anti-immigrant hostility in the United States, which I take to be connected to the longevity of white normativity as the basis for American identity. I then critically assess how the idea of national belonging is crucial to the perpetuation of white-ways-of-being, especially when citizenship has historically been a venue for the embodiment of racial and even colonial privilege. I conclude by posing several questions about the nature of racial identities and racism that suggest new avenues for further research on racial embodiment in a “postracial” era. pp. 65–90. (shrink)

ABSTRACT: In its historical deployment, socialist thought has attracted the attention of numerous experts and thinkers. The results reached from the above mentioned efforts, are quite irregular in fact. These studies are very often linked the marxist tradition, that shifted its identity to label previous social reformers as "utopian socialists". Specifically, our academic Spanish tradition has traditionally been dependant -historically and intellectually- on other Continental currents of thought. We state, that the preeminence and fundamental influence on our Spanish culture in (...) the Iberian Peninsula, has traditionally had its origin here, between modernity and industrialism, in France. Consistently, contributions concerning authors like Saint-Simon, Fourier or Cabet do exist. However, it is necessary to say that there is a bibliographical and very significant emptiness around one of the most relevant figures of European history in the 19th Century. Such emptiness has to do with the absence of publications concerning Robert Owen and his meaning in Spanish. Key words: Christianity, Modernity, Industrialism, Utopian Socialism, Socialism, Rationality, History. (shrink)

We have to gain from recognizing a relation between epistemic agents and the parts of subject matters that play a role in their cognitive lives. I call this relation “grasping”. Namely, I zone in on one notion of having a partial grasp of a subject matter—that of agents grasping part of the subject matter that they are attending to—and characterize it. I propose that giving up the idealization that we fully grasp the subject matters we attend to allows one to (...) more realistically characterize the epistemic life of agents. To show this, I propose an epistemic logic with partial grasp that has in mind considerations from first-order aboutness theory with the aim of avoiding certain forms of logical omniscience, and which provides an alternative to immanent closure (Yablo Aboutness, Princeton University Press, 2014). (shrink)

Resumen. El presente texto se centra en la crítica que el pensamiento decolonial ha dirigido a la cultura occidental, focalizada en la modernidad, como intrínsecamente violenta y respecto de la cual las culturas que sufrieron la colonización debieran cortar radicalmente. Con el objetivo de poner en cuestión algunos aspectos centrales de este planteamiento se analizan críticamente sus conceptos de modernidad, de geopolítica del conocimiento y de cultura. Palabras clave: modernidad; cultura; geopolítica del conocimiento. [en] The Critique of Modernity in the (...) Decolonial Thought Abstract. This paper takes as its central issue the criticism that the decolonial thought has made to the Western culture, focused on modernity, as an internally violent culture. For this reason, the decolonial authors think that the cultures which have suffered the colonization should set a cut in regard of Western culture. We try to put in question some central aspects of this conception, as their concepts of modernity, culture, and geopolitics of knowledge. Keywords: Modernity; Culture; Geopolitics of Knowledge. (shrink)

En el presente trabajo se pretende reconstruir la noción de imaginación expuesta por Kant en la "Crítica de la razón pura", en su primera edición, y en la "Crítica del juicio" con el fin de poder dilucidar un posible papel de este concepto en el marco de la ética kantiana. -/- .

It is one thing to hold that merely statistical evidence is _sometimes_ insufficient for rational belief, as in typical lottery and profiling cases. It is another thing to hold that merely statistical evidence is _always_ insufficient for rational belief. Indeed, there are cases where statistical evidence plainly does justify belief. This project develops a dispositional account of the normativity of statistical evidence, where the dispositions that ground justifying statistical evidence are connected to the goals (= proper function) of objects. There (...) are strong intuitive motivations for doing this. For we can turn almost any case of _non-justifying_ merely statistical evidence into a case of _justifying_ merely statistical evidence by adding information about the dispositions and goals of the objects involved. The resulting view not only helps us understand when and why merely statistical evidence is normatively significant, but it also helps us understand how statistical evidence relates to more standard forms of evidence (perceptual, testimonial). The emerging view also has surprising applications, as it imposes limitations on the epistemic value of fine-tuning arguments for theism as well as undermines a standard class of case-based arguments for moral encroachment. (shrink)

The distinction between propositional and doxastic justification is the distinction between having justification to believe P (= propositional justification) versus having a justified belief in P (= doxastic justification). The focus of this paper is on doxastic justification and on what conditions are necessary for having it. In particular, I challenge the basing demand on doxastic justification, i.e., the idea that one can have a doxastically justified belief only if one’s belief is based on an epistemically appropriate reason. This demand (...) has been used to refute versions of coherentism and conservatism about perceptual justification as well as to defend phenomenal “conservatism” and other views besides. In what follows I argue that there is virtually no reason to think there is a basing demand on doxastic justification. I also argue that even if the basing demand were true, it would still fail to serve the dialectical purposes for which it has been employed in arguments concerning coherentism, conservatism, and phenomenal “conservatism”. I conclude by discussing the fact that knowledge has a basing demand and show why this needn’t raise the same sort of problems for coherentism and conservatism that doxastic justification’s basing demand seemed to. (shrink)

ABSTRACTWhat conditions must be satisfied if a group is to count as having a justified belief? Jennifer Lackey has recently argued that any adequate account of group justification must be sensitive to both the evidence actually possessed by enough of a group's operative members as well as the evidence those members should have possessed. I first draw attention to a range of objections to Lackey's specific view of group justification and a range of concrete case intuitions any plausible view of (...) group justification must explain. I then offer an alternative view of group justification where the basic idea is that group justification is a matter of groups responsibly responding to their total evidence. This view both avoids the problems facing Lackey's account and also explains the relevant concrete case intuitions. (shrink)

I provide a novel knowledge-first account of justification that avoids the pitfalls of existing accounts while preserving the underlying insight of knowledge-first epistemologies: that knowledge comes first. The view I propose is, roughly, this: justification is grounded in our practical knowledge (know-how) concerning the acquisition of propositional knowledge (knowledge-that). I first refine my thesis in response to immediate objections. In subsequent sections I explain the various ways in which this thesis is theoretically superior to existing knowledge-first accounts of justification. The (...) upshot is a virtue-theoretic, knowledge-first view of justification that is internalist-friendly and able to explain more facts about justification than any other available view. (shrink)

In this paper I consider whether it is possible to cause an event by letting it happen.

[Significantly updated in Chapter 6 of Awareness and the Substructure of Knowledge] In order for a reason to justify an action or attitude it must be one that is possessed by an agent. Knowledge-centric views of possession ground our possession of reasons, at least partially, either in our knowledge of them or in our being in a position to know them. On virtually all accounts, knowing P is some kind of non-accidental true belief that P. This entails that knowing P (...) is a kind of non-accidental true representation that P. I outline a novel theory of the epistemic requirement on possession in terms of this more general state of non-accidental true representation. It is just as well placed to explain the motivations behind knowledge-centric views of possession, and it is also better placed to explain the extent of the reasons we possess in certain cases of deductive belief-updates and cases involving environmental luck. I conclude with three reflections. First, I indicate how my arguments generate a dilemma for Errol Lord’s view that possessing reasons is just a matter of being in a position to manifest one’s knowledge how to use them. Second, I explain how my view can simultaneously manage cases of environmental luck without falling prey to lottery cases. Finally, I sketch the direction for a further range of counterexamples to knowledge-centric theories of possession. (shrink)

This work explores the increasing militarization of borders throughout the world, particularly the United States border with Mexico. Rather than further rhetoric of "border security," this work views increases in guards, technology and the building of walls as militarized action. The goal of this essay is to place the onus upon states to justify their actions at borders in ways that do not appeal to tropes of terrorism. This work then explores how a logic of security infiltrates philosophical discussions of (...) "the right to exclude," thereby curtailing the ability to see borders in any other way than as a locale that must be militarized. Specifically, I analyze the work of Michael Blake and his juridical theory of immigration restrictions. I argue that his work necessitates the walling of borders and removal of those who create new obligations for current members of existing political institutions. (shrink)

[This papers explores a novel case for the normativity of knowledge for belief – something that is compatible with the knowledge/factual awareness distinction I've explored elsewhere.] There are two different kinds of enkratic principles for belief: evidential enkratic principles and normative enkratic principles. It’s frequently taken for granted that there’s not an important difference between them. But evidential enkratic principles are undermined by considerations that gain no traction at all against their normative counterparts. The idea that such an asymmetry exists (...) between evidential and normative enkratic principles is surprising all on its own. It is also something that calls out for explanation. Similarly, the considerations that undermine evidential enkratic principles also undermine certain narrow-scope evidential principles. This too generates explanatory questions. I show how a knowledge-first view of rationality can easily address these explanatory questions. Thus we have one more reason to put knowledge first in [some areas of] epistemology. (shrink)

Agents know some but not all logical consequences of what they know. Agents seem to be neither logically omniscient nor logically incompetent. Yet finding an intermediate standard of minimal rationality has proven difficult. In this paper, I take suggestions found in the literature (Lewis, 1988; Hawke, Özgün and Berto, 2020; Plebani and Spolaore, 2021) and join the forces of subject matter and impossible worlds approaches to devise a new solution to this quandary. I do so by combining a space of (...) FDE worlds (Berto and Jago, 2019) with a Lewisian (1988) understanding of subject matters as partitions. By doing so, I show how subject matters impose some order in the anarchic space of FDE worlds, while the worlds allow for distinctions between contents which would not otherwise be available. Combining the two approaches, then, brings us closer to the desired closure principles for knowledge of minimally rational agents. (shrink)

Sometimes it’s reasonable to reduce confidence in a proposition in response to gaining etiological information. Suppose, for example, a theist learns that her theism is ‘due to’ her religious upbringing. There is a clear range of cases where it would be reasonable for her to respond by slightly decreasing her confidence in God’s existence. So long as reasonability and justification are distinct, this reasonability claim would appear consistent with the thesis that this kind of etiological information cannot, all by itself, (...) affect one’s justification. In what follows, I argue that this is mistaken. For, even if reasonability and justification are distinct, the reasonability of decreasing confidence in response to etiological information must be explained in terms of a decrease in justification. The argument to follow threatens not only the stronger thesis that etiological information never defeats justification but the substantially weaker thesis, advocated by various authors, that justification is defeated by etiological information in only a limited range of circumstances. I go on to show how the arguments en route to this conclusion have much wider epistemological ramifications. (shrink)

ABSTRACT: In this text, we are going to try to introduce a few brief notes - without excessive pretensions -, concerning those things that, from a historical and also from an intellectual and point of view, surround the figures of Robert Owen, Fourier or Saint Simon. Certainly, intellectually, our sources do not let us notice a very specific influence on the "utopian socialists" of the 19th Century. It will be very difficult to find historical evidence. However, what we can do (...) is to assume the French Revolution of 1789 as a turning point for the radical traditions, both British and Continental, to introduce Romanticism as the real source from which the utopian nineteenth-century thought was derived from. Then, Romanticism is where we will be able to read something about Robert Owen. Likewise, we will approach a very succinct reading of paleo-socialism, focusing on the context of the British Islands where the Industrial Revolution took place to become another great event in the lifetime of the "utopian socialists". Key words: Christianity, Modernity, Industrialism, Utopian Socialism, Socialism, Rationality, History. (shrink)

ABSTRACT: In the present text, we are going to introduce a series of notes without excessive pretensions. In these pages, we will try to study figures like Cabet, Fourier or Saint - Simon, and we will do so in order to achieve better understanding concerning their own historical and their own intellectual context. Consequently and leaving our papers on Robert Owen behind, we plan to set special emphasis on the European Continent now. In a special way, we raise awareness on (...) the very significant role that these "utopian socialists" played between modernity and industrial modernity, and also between the 18th and 19th Centuries. Key words: Christianity, Modernity, Industrialism, Utopian Socialism, Socialism, Rationality, History. (shrink)

In Meditations on First Philosophy, René Descartes argues that one cannot trust one’s senses since they are not a reliable source of obtaining knowledge of the world. One of Descartes’s main contentions to support such an argument is from his explanation of dreams, where one can feel one is awake but instead one is dreaming. Native Americans, however, may argue that the experiences one has in dreams are real and are a source of knowledge of the real world. Although Descartes (...) uses dreams to support his argument, some Native Americans have a different take on dreams. Dreams for Native Americans are a source of knowledge as well as a source for obtaining one’s identity. Gregory Cajete, in American Indian Thought, notes that “Dreams and Visions are a natural means for accessing knowledge and establishing relationship to the world. They are encouraged and facilitated.” In other words, it is through dreams that individuals are guided, destined, and informed. Therefore, dreams as understood by some Native Americans are an extension of reality that anticipate events that will happen or can happen. The focus of this paper is an exploration of the philosophical and religious epistemology pertaining to Native Americans as described in their accounts of dreams. (shrink)

A growing body of work in free speech theory is interested in the nature of counterspeech, i.e. speech that aims to counteract the effects of harmful speech. Counterspeech is usually defined in opposition to legal responses to harmful speech, which try to prevent such speech from occurring in the first place. In this paper we challenge this way of carving up the conceptual terrain. Instead, we argue that our main classificatory division, in theorising responses to harmful speech, should be between (...) pro-discursive and anti-discursive responses. Some legal responses to harmful speech, so we argue, make a positive discursive contribution in their own right. That is, legal restrictions on harmful speech can have a function that is importantly similar to speech that aims at countering the effects of harmful speech. (shrink)

Various sexist and racist beliefs ascribe certain negative qualities to people of a given sex or race. Epistemic allies are people who think that in normal circumstances rationality requires the rejection of such sexist and racist beliefs upon learning of many counter-instances, i.e. members of these groups who lack the target negative quality. Accordingly, epistemic allies think that those who give up their sexist or racist beliefs in such circumstances are rationally responding to their evidence, while those who do not (...) are irrational in failing to respond to their evidence by giving up their belief. This is a common view among philosophers and non-philosophers. But epistemic allies face three problems. First, sexist and racist beliefs often involve generic propositions. These sorts of propositions are notoriously resilient in the face of counter-instances since the truth of generic propositions is typically compatible with the existence of many counter-instances. Second, background beliefs can enable one to explain away counter-instances to one’s beliefs. So even when counter-instances might otherwise constitute strong evidence against the truth of the generic, the ability to explain the counter-instances away with relevant background beliefs can make it rational to retain one’s belief in the generic despite the existence of many counter-instances. The final problem is that the kinds of judgements epistemic allies want to make about the irrationality of sexist and racist beliefs upon encountering many counter-instances is at odds with the judgements that we are inclined to make in seemingly parallel cases about the rationality of non-sexist and non-racist generic beliefs. Thus epistemic allies may end up having to give up on plausible normative supervenience principles. All together, these problems pose a significant prima facie challenge to epistemic allies. In what follows I explain how a Bayesian approach to the relation between evidence and belief can neatly untie these knots. The basic story is one of defeat: Bayesianism explains when one is required to become increasingly confident in chance propositions, and confidence in chance propositions can make belief in corresponding generics irrational. (shrink)

In this paper I lay the foundations for the construction of an affective quality space. I begin by outlining what quality spaces are, and how they have been constructed for sensory qualities across different perceptual modalities. I then turn to tackle four obstacles that an affective quality space might face that would make an affective quality space unfeasible. After showing these obstacles to be surmountable, I propose a number of conditions and methodological constraints that should be satisfied in attempts to (...) construct an affective quality space. Before concluding, I detail the high explanatory pay-off such a project promises. (shrink)

In the United States today, much interpersonal racism is driven by corrupt forms of self-preservation. Drawing from Jean- Jacques Rousseau, I refer to this as self-love racism. The byproduct of socially-induced racial anxieties and perceived threats to one’s physical or social wellbeing, self-love racism is the protective attachment to the racialized dimensions of one’s social status, wealth, privilege, and/or identity. Examples include police officer related shootings of unarmed Black Americans, anti-immigrant sentiment, and the resurgence of unabashed white supremacy. This form (...) of racism is defined less by the introduction of racism into the world and more on the perpetuation of racially unjust socioeconomic and political structures. My theory, therefore, works at the intersection of the interpersonal and structural by offering an account of moral complacency in racist social structures. My goal is to reorient the directionality of philosophical work on racism by questioning the sense of innocence at the core of white ways-of-being. (shrink)

El Anti-Excepcionalismo Lógico afirma que la Lógica es como cualquier otra ciencia. Si esta afirmación es cierta, entonces ella no sólo es revisable, sino que además todo lo que se puede decir sobre las ciencias aplica, mutatis mutandis, para la misma. El propósito de este artículo es explorar esta consecuencia del Anti-Excepcionalismo Lógico, acercando a la Filosofía de la Lógica el marco teórico de las Máquinas Nomológicas de Nancy Cartwright. De acuerdo con esta visión, lo que hay de verdadero en (...) las teorías científicas no está en el mundo sino en sus modelos: sistemas altamente controlados, estables, artificiales y específicos, dentro de los cuales se manifiestan regularidades sistematizables y enseñables. Mi afirmación es que lo mismo puede decirse de la Lógica: ella no captura las Leyes del Pensamiento o de la Razón, porque el pensamiento y la razón no están gobernados necesariamente por leyes. Sobre lo que sí puede decirse que versan las Leyes de la Lógica son metafísicas posibles: historias acerca de qué son las proposiciones, el pensamiento, la verdad y la validez. A fin de ilustrar y defender esta tesis, presento un ejemplo de Máquina Nomológica de la Lógica Clásica, basada en una lectura original del Tractatus de Wittgenstein, e investigo algunas de sus consecuencias. Mi conclusión es que esta imagen de la Lógica impacta en el problema de la revisión de la Lógica Clásica, en la medida en que muestra que dicha revisión no necesariamente responde a un proceso racional de adecuación de la teoría a los hechos porque los “hechos” relevantes no son anteriores a la teoría misma, sino que están moldeados y conducidos por ella. Palabras clave: Anti-Excepcionalismo Lógico, Abductivismo, Máquinas Nomológicas, Revisión Lógica, Filosofía de la Lógica. (shrink)