The Protein Ontology (PRO; http://purl.obolibrary.org/obo/pr) formally defines and describes taxon-specific and taxon-neutral protein-related entities in three major areas: proteins related by evolution; proteins produced from a given gene; and protein-containing complexes. PRO thus serves as a tool for referencing protein entities at any level of specificity. To enhance this ability, and to facilitate the comparison of such entities described in different resources, we developed a standardized representation of proteoforms using UniProtKB as a sequence reference and PSI-MOD as a post-translational modification (...) reference. We illustrate its use in facilitating an alignment between PRO and Reactome protein entities. We also address issues of scalability, describing our first steps into the use of text mining to identify protein-related entities, the large-scale import of proteoform information from expert curated resources, and our ability to dynamically generate PRO terms. Web views for individual terms are now more informative about closely-related terms, including for example an interactive multiple sequence alignment. Finally, we describe recent improvement in semantic utility, with PRO now represented in OWL and as a SPARQL endpoint. These developments will further support the anticipated growth of PRO and facilitate discoverability of and allow aggregation of data relating to protein entities. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

The Protein Ontology (PRO; http://proconsortium.org) formally defines protein entities and explicitly represents their major forms and interrelations. Protein entities represented in PRO corresponding to single amino acid chains are categorized by level of specificity into family, gene, sequence and modification metaclasses, and there is a separate metaclass for protein complexes. All metaclasses also have organism-specific derivatives. PRO complements established sequence databases such as UniProtKB, and interoperates with other biomedical and biological ontologies such as the Gene Ontology (GO). PRO relates to (...) UniProtKB in that PRO’s organism-specific classes of proteins encoded by a specific gene correspond to entities documented in UniProtKB entries. PRO relates to the GO in that PRO’s representations of organism-specific protein complexes are subclasses of the organism-agnostic protein complex terms in the GO Cellular Component Ontology. The past few years have seen growth and changes to the PRO, as well as new points of access to the data and new applications of PRO in immunology and proteomics. Here we describe some of these developments. (shrink)

In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the (...) domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users, accessible at: http://purl.obolibrary.org/obo/ncro.owl. (shrink)

In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the (...) domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users, accessible at: http://purl.obolibrary.org/obo/ncro.owl. (shrink)

Le Père Ignace Carbonnelle, l'un des principaux fondateurs de la Société scientifique de Bruxelles en 1875 et son secrétaire général depuis cette époque, décède inopinément en 1889 après une quin­zaine d'années durant lesquelles il fut «l'homme fort» de ladite Société. Aussitôt, la Revue des questions scienti­fiques annonce la triste nouvelle, promettant, pour un prochain numéro, une étude détaillée de sa vie et de son œuvre. Elle ne paraîtra jamais, de sorte que sa mort ne fut pas saluée avec l'ampleur qu'on (...) était en droit d'attendre. Et pour cause ! Au ter­me d'une enquête digne d'un roman policier, cette étude révèle que Rome, agacée par l'atomisme de Carbonnelle, profita de sa mort pour rappeler à l'ordre la Société en l'invitant à marcher dans les pas de l'Aquinate. En réponse à cette pressante invi­tation et par un excès de zèle non requis, la Société élut comme président le célèbre thomiste français Edmond Domet de Vor­ges, cependant que le mathématicien Paul Mansion s'attacha d'établir, à partir des publications de Pierre Duhem prônant un retour à une physique des qualités, que la Société se conformait bien, mais à sa manière, aux injonctions romaines. ––– Fr. Ignace Carbonnelle, who founded the Brussels Scientific Society in 1875 and was from this date onwards her Secretary General, passed away suddenly in 1889, after fifteen years during which he was the leading figure of the aforementioned Society. “La Revue des Question scientifique” announced the sad news but promised that their next publication would include a detailed article on the great man and his works. Sadly this article never appeared, meaning that the passing of Fr. Carbonnelle was not marked with the importance which we might have otherwise expected. For what reason, you may well ask? After a detailed investigation, worthy of Agatha Christie herself, it would appear that Rome had been rather alarmed by the “atomism” present in Fr. Carbonnelle's reflections, and had taken the opportunity of his death to invite the Scientific Society to opinions more in line with those of St Thomas. In response to this firmly worded invitation, and with overzealous spontaneity, the Society elected the celebrated French Thomiste Edmond Domet de Vorges as their new President. At the same time the mathematician Paul Mansion relied on the publications of Pierre Duhem, which advocated a stronger adhesion to a physics of an object's qualities, to establish that the Society was, in fact, well aligned with the desires of Rome. (shrink)

l. There is an antinomy in Hare's thought between Ought-Implies-Can and No-Indicatives-from-Imperatives. It cannot be resolved by drawing a distinction between implication and entailment. 2. Luther resolved this antinomy in the l6th century, but to understand his solution, we need to understand his problem. He thought the necessity of Divine foreknowledge removed contingency from human acts, thus making it impossible for sinners to do otherwise than sin. 3. Erasmus objected (on behalf of Free Will) that this violates Ought-Implies-Can which he (...) supported with Hare-style ordinary language arguments. 4. Luther a) pointed out the antinomy and b) resolved it by undermining the prescriptivist arguments for Ought-Implies-Can. 5. We can reinforce Luther's argument with an example due to David Lewis. 6. Whatever its merits as a moral principle, Ought-Implies-Can is not a logical truth and should not be included in deontic logics. Most deontic logics, and maybe the discipline itself, should therefore be abandoned. 7. Could it be that Ought-Conversationally-Implies-Can? Yes - in some contexts. But a) even if these contexts are central to the evolution of Ought, the implication is not built into the semantics of the word; b) nor is the parallel implication built into the semantics of orders; and c) in some cases Ought conversationally implies Can, only because Ought-Implies-Can is a background moral belief. d) Points a) and b) suggest a criticism of prescriptivism - that Oughts do not entail imperatives but that the relation is one of conversational implicature. 8. If Ought-Implies-Can is treated as a moral principle, Erasmus' argument for Free Will can be revived (given his Christian assumptions). But it does not 'prove' Pelagianism as Luther supposed. A semi-Pelagian alternative is available. (shrink)

There are two motivations commonly ascribed to historical actors for taking up statistics: to reduce complicated data to a mean value (e.g., Quetelet), and to take account of diversity (e.g., Galton). Different motivations will, it is assumed, lead to different methodological decisions in the practice of the statistical sciences. Karl Pearson and W. F. R. Weldon are generally seen as following directly in Galton’s footsteps. I argue for two related theses in light of this standard interpretation, based on a reading (...) of several sources in which Weldon, independently of Pearson, reflects on his own motivations. First, while Pearson does approach statistics from this "Galtonian" perspective, he is, consistent with his positivist philosophy of science, utilizing statistics to simplify the highly variable data of biology. Weldon, on the other hand, is brought to statistics by a rich empiricism and a desire to preserve the diversity of biological data. Secondly, we have here a counterexample to the claim that divergence in motivation will lead to a corresponding separation in methodology. Pearson and Weldon, despite embracing biometry for different reasons, settled on precisely the same set of statistical tools for the investigation of evolution. (shrink)

Values are an important part of human existence, his society and human relations. All social, economic, political, and religious problems are in one sense is reflection of this special abstraction of human knowledge. We are living in a globalized village and thinking much about values rather than practice of it. If we define religion and spirituality we can say that religion is a set of beliefs and rituals that claim to get a person in a right relationship with God, and (...) spirituality is a focus on spiritual things and the spiritual world instead of physical/earthly things. If we think rationally we can find the major evils related to religion exiting in present society are due to lack of proper understanding of religion and spirituality. If we really know our own religions and values associated with it, we can create a beautiful world, full or love and respect for each and every human being. The proper knowledge and practice of any religion’s values can make an integrated man. In the book, The Buddha and His Dhamma, Dr. Ambedkar elucidated the significance and importance of Dhamma in human life. The Dhamma maintained purity of life, which meant abstains from lustful, evil practices. The Dhamma is a perfection of life and giving up craving. Dhamma’s righteousness means right relation of man to man in all sphere of life. The basic idea underlying religion is to create an atmosphere for the spiritual development of the individual. He said that Knowing the proper ways and means is more important than knowing the ideal. The major objective of this paper is to the study the religious philosophy of Dr. B.R. Ambedkar and to study how he established that religious and spiritual values enables religious people in particular and humanity at large to solve contemporary problems. (shrink)

R. G. Collingwood’s 'The Principles of Art' argues that art is the expression of emotion. This dissertation offers a new interpretation of that philosophy, and argues that this interpretation is both hermeneutically and philosophically plausible. The offered interpretation differs from the received interpretation most significantly in treating the concept of ‘art’ as primarily scalarly rather than binarily realisable (this is introduced in ch. 1), and in understanding Collingwood’s use of the term ‘emotion’ more broadly (introduced in ch. 2). -/- After (...) the exposition of ch. 1, the remainder of that chapter and the subsequent three chapters are each centred around one sort of objection. In ch. 1, I consider the objection that Collingwood’s scalar understanding of ‘art’ is deviant and unhelpful. I respond by first observing that the understanding is not deviant, and second that it is more philosophically and artistically illuminating. In ch. 2, I consider the objection that Collingwood’s understanding of ‘emotion’ is so narrow that it fails to do justice to the fact that art can be philosophically potent. I respond that his understanding of ‘emotion’ is broad enough that this objection fails. In ch. 3, I consider the objection that Collingwood has no theoretical room for the prima facie plausible thought that some emotions are not worth expressing in art. In response, I reinterpret the points that appear to support this contention in a way that makes them both more plausible and more Collingwoodian. Finally, in ch. 4, I consider the objection that Collingwood does not have the theoretical room to do justice to the value of the delight we take in art. I respond by arguing that although he does not have this room to say that this delight is itself an artistic value, it does yet have an important place in his philosophy. (shrink)

Dr. B. R. Ambedkar is one of the most eminent intellectual figures of modern India. The present year is being celebrated as 125th Birth Anniversary of Dr. B. R. Ambedkar. Educationist and humanist from all over the world are celebrating 125th Birth Anniversary of Dr. B. R. Ambedkar by organizing various events and programmes. In this regard the Centre for Positive Philosophy and Interdiscipinary Studies (CPPIS) Pehowa (Kurukshetra) took an initiative to be a part of this mega event by organizing (...) an national level esssay competition for students, publication of books, posters and research journals on Dr. B.R. Ambedkar. Dr. B.R. Ambedkar’s ideas, writings and outlook could well be characterized as belonging to that trend of thought called Social Humanism. He developed a socio-ethical philosophy and steadfastly stood for human dignity and freedom, socio-economic justice, material prosperity and spiritual discipline. He showed the enlightening path for Indian society via his ideals of freedom, equality and fraternity and made India a democratic country. The complete works of Dr. B.R. Ambedkar published by the Governemtn of Maharastra and it has taken about 25 years to complete this initiative in 21 Volumes with the name, “Dr. Babasaheb Ambedkar: Writing and Speeches” and covers 14000 pages. In the words of Trilochan Sing, “Above all, Dr. Ambedkar is a philosopher. Those who read his books cannot be failed to be impressed with steadffastness with which he pursues truth; and only those who have dispassionately read his books can frame true estimate of the greatness of the man”. These 21 Volumes includes books published by Dr. B.R. Ambedkar himself and unpublished writings and speaches too. The present volume entitled “Dr. B.R. Ambedkar: The Maker of Modern India” contains 12 research papers on the different aspects of philosophy of Dr. B.R. Ambedkar written by academicians from different branches of knowledge. You can find a variety of dialogues and concen about the theme of the book here. We are not defending this book as a highly an intellectual work but a smaller step to know the various aspects of this great personality and is a start to study his vast wisdom. You suggestions and comments are welcome to its first hand review version. (shrink)

To follow the legacy of Dr. B.R. Ambedkar, a RUSA Sponsored One-Day Facutly Development Programme on “Dr. B.R. Ambedkar, Indian Constitution and Indian Society” organised by the Department of Philosophy and P.G. Department of Public Administation held on 20th January, 2016 was a creative and fruitful effort to bring together the scholars and academicians from several disciplines to participate in the deliberations related to the conceptual understanding and insights of the philosophy of Dr. B.R. Ambedkar.

Scholars are grateful to Cyril Lionel Robert James (1901-1989) and Herbert Aptheker (1915-2003) for their pioneering work in the field of slave revolts. What they've virtually never mentioned, however, let alone explored, was Aptheker’s practice of rendering James invisible. It is highly improbable that Aptheker did not know either of James or of his noteworthy study of the Haitian Revolution, given that the latter was related to the slave revolts that Aptheker did study. Aptheker’s neglect of James was not an (...) anomaly, but rather symptomatic of an ideology that rationalized extreme oppression. (shrink)

Originally published in 1991, The Laboratory of the Mind: Thought Experiments in the Natural Sciences, is the first monograph to identify and address some of the many interesting questions that pertain to thought experiments. While the putative aim of the book is to explore the nature of thought experimental evidence, it has another important purpose which concerns the crucial role thought experiments play in Brown’s Platonic master argument.In that argument, Brown argues against naturalism and empiricism (Brown 2012), for mathematical Platonism (...) (Brown 2008), and from the Platonist-friendly, abstract universals posited by the Dretske-Tooley-Armstrong (DTA) account of the laws of nature to a more general, physical Platonism. The Laboratory of the Mind is where he takes this final step. (shrink)

La característica central del pensamiento filosófico del siglo XX (si más no, de la llamada a día de hoy 'filosofía analítica') ha sido el interés por el estudio del lenguaje. El lenguaje religioso no ha sido una excepción a este interés. Uno de los ejemplos más tempranos de esta preocupación por el estudio del lenguaje religioso es el análisis propuesto por R. B. Braithwaite en su "An Empiricist's View of the Nature of Religious Belief" (1955). Dicho muy brevemente, la idea (...) básica de Braithwaite es que el lenguaje religioso no describe el mundo: aquellos que realizan una afirmación de índole religiosa no están aceptando la verdad de una proposición sino que están simplemente expresando su compromiso con un determinado código de conducta. Es por ello, dice Braithwaite, que adoptar una creencia religiosa no consiste en aceptar que el mundo se corresponde con una descripción de hechos determinada, sino en comprometerse a actuar de acuerdo con un código de conducta. El objetivo de este artículo es ofrecer un análisis crítico de la propuesta de Braithwaite. (shrink)

Throughout Peirce’s writing, we witness his developing vision of a machine that scientists will eventually be able to create. Nadin (2010) raised the question:Why do computer scientists continue to ignore Peirce’s sign theory? A review of the literature on Peirce’s theory and the semiotics machine reveals that many authors discussed the machine;however, they donot differentiate between a physical computer machine and its software. This paper discusses the problematic issues involved in converting Peirce’s theory into a programming language, machine and software (...) application. We demonstrate this challenge by introducing Peirce’s sign theory as a software application that runs under an open-source R environment. (shrink)

XENOLOGY AND XENOTOPOGRAPHY OF BERNHARD WALDENFELS The paper strives to adapt Bernhard Waldenfels’ xenology and so called ‘xenotopography’ for the philosophico-literary studies in fantastic world-building with a special concern of the ‘portal-quest’ model of fantasy and SF. Following Waldenfel’s remarks on the nature of post- Husserlian diastasis of our world [Heimwelt] and otherworld [Fremdwelt] and acknowledging the consequences of allocating one’s attitude towards the otherness in the symbolical borderland [‘sphere of intermonde’] in between, it is examined whether such a model (...) can occur in the fantastic literature and what may be the consequence of xenotopographic reconsideration of its basic ontological premises. Additionally, the article offers an original xenotopograpfic model of worldbuilding which addresses three carefully chosen case studies of fantastic worlds from Orson Scott Card’s Ender’s Game tetralogy, Neil Gaiman’s Stardust and George R. R. Martin’s The Song of Ice and Fire. In the end, it is suggested that hitherto presented xenotopography gravely inspired a postmodern shift in the genres of fantasy and SF which results in more ethically conscious representations of the otherness and even more concise and alien comprehensive world-building. (shrink)

Karen Neander's A Mark of the Mental is a noteworthy and novel contribution to the long-running project of naturalizing intentionality. The aim of the book is to “solve the part of Brentano’s problem that is within reach” (3). Brentano's problem is the problem of explaining intentionality; the part of this problem that is supposedly within reach is that of explaining nonconceptual sensory-perceptual intentionality; and Neander aims to solve it via an informational teleosemantic theory. In this review, we provide a (...) chapter-by-chapter summary followed by some discussion. We argue that Neander's theory yields incorrect predictions in some cases, that the methodological argument for informational teleosemantics does not succeed, and that it is not clear that the book makes contact with its initial target, the everyday phenomenon of intentionality. (shrink)

Wild animal reproduction poses an important moral problem for animal rights theorists. Many wild animals give birth to large numbers of uncared-for offspring, and thus child mortality rates are far higher in nature than they are among human beings. In light of this reproductive strategy – traditionally referred to as the ‘r-strategy’ – does concern for the interests of wild animals require us to intervene in nature? In this paper, I argue that animal rights theorists should embrace fallibility-constrained interventionism: the (...) view that intervention in nature is desirable but should be constrained by our ignorance of the inner workings of ecosystems. Though authors sometimes assume that large-scale intervention requires turning nature into an enormous zoo, I suggest an alternative. With sufficient research, a new form of gene editing called CRISPR promises to one day give us the capacity to intervene without perpetually interfering with wild animals’ liberties. (shrink)

A review of Karen Bennett's /Making Things Up/.

This paper explores R. D. Laing's application of existential and phenomenological tradtions, specifically Hegel and Heidegger, to his groundbreaking work with psychotic process as well as psychotherapeutic practice more generally.

Mit seinem Einfluß auf die Entwicklung der Physiologie, Physik und Geometrie ist Hermann von Helmholtz wie kaum ein anderer Wissenschaftler der zweiten Hälfte des 19. Jahrhunderts repräsentativ für die Naturforschung in Deutschland. Nicht weniger repräsentativ nimmt sich die Entwicklung seiner Wissenschaftsauffassung aus. Während er bis in die späten 60er Jahre einen emphatischen Wahrheitsanspruch der Wissenschaft vertrat, begann er in der nachfolgenden Zeit, die Geltungsbedingungen der wissenschaftlichen Erkenntnis einer Relativierung zu unterwerfen, die zusammenfassend als Hypothetisierung bezeichnet werden kann. Helmholtz entwickelte damit (...) schon im vergangenen Jahrhundert Ansätze einer Wissenschaftsauffassung , die in erstaunlichem Umfang in die Richtung der Moderne weisen. Wie nah er späteren Wissenschaftsauffassungen bereits gekommen ist, kann ein Vergleich mit Karl R. Poppers Forschungslogik illustrieren. In seiner Forschungslogik ist die Hypothetisierung der wissenschaftlichen Erkenntnis entschieden weiter vorangeschritten als in Heimholtz' Wissenschaftstheorie. Was sich bei Helmholtz erst vage abzuzeichnen beginnt, ist bei ihm bereits explizit formuliertes Programm geworden. Obwohl HeImholtz und Popper in keiner direkten wissenschaftstheoretischen Entwicklungslinie stehen und Popper sich in seinen Schriften auch nur sehr selten und beiläufig auf Helmholtz bezieht, finden sich dennoch überraschende und bisher nicht beachtete Berührungspunkte, die insbesondere dann hervortreten, wenn man Heimholtz' Wissenschaftsauffassung vor dem Hintergrund von Poppers Forschungslogik betrachtet. (shrink)

Wilfred Sellars's deeply original and systematic thought continues to inspire into the twenty-first century. Part of the explanation must be that Sellars's struggle to integrate a Kantian-Wittgensteinian normative view of meaning and intentionality with a naturalistic outlook remains at the forefront of philosophical inquiry. To acknowledge the deep impact that Sellars has had on their work, a list of prominent, contemporary philosophers honor Sellars's legacy in a volume craftily edited by James R. O'Shea with a superb introduction. Like Sellars's own (...) work, the contributions are distributed across a wide range of topics from, roughly, philosophy of perception, philosophy of... (shrink)

With his influence on the development of physiology, physics and geometry, Hermann von Helmholtz – like few scientists of the second half of the 19th century – is representative of the research in natural science in Germany. The development of his understanding of science is not less representative. Until the late sixties, he emphatically claimed the truth of science; later on, he began to see the conditions for the validity of scientific knowledge in relative terms, and this can, in summary, (...) be referred to as hypothesizing. Already in the past century, HeImholtz made first approaches to an understanding of science, which were incompatible with his own former position and which pointed to the modern age to an astonishingly large extent. A comparison with Karl R. Popper's logic of research will illustrate how closely he nevertheless approached modern understanding of science. In Popper's logic of research, hypothesizing of scientific knowledge is definitely much more advanced than in Helmholtz's theory of science. What begins vaguely to emerge with Helmholtz has already become an explicitly formulated programme with Popper. Although HeImholtz and Popper are not on a direct line of epistemological development and Popper refers to HeImholtz only rarely and casually, there are in fact surprising points of contact which have not been taken notice of so far and which appear above all if one looks at Helmholtz's understanding of science against the background of Popper's logic of research. (shrink)

Review of: R. Steven Turner, In the Eye's Mind: Vision and the Helmholtz-Hering Controversy. xiv + 338 pp., frontis., illus., figs., tables, bibl., index. Princeton, N.J.: Princeton University Press, 1994.

In her re-analysis of the evidence presented in Klein and Nichols (2012) to support their argument that patient R.B. temporarily lost possessory custody of consciously apprehended objects (in this case, objects that normally would be non-inferentially taken as episodic memory), Professor Roache concludes Klein and Nichols's claims are untenable. I argue that Professor Roache is incorrect in her re-interpretation, and that this is due, in part, to lack of sufficient familiarity with psychological theory on memory as well as clinical literature (...) on felt loss of ownership of one’s intentional objects. (shrink)

Karen Stohr’s book On Manners argues persuasively that rules of etiquette, though conventional, play an essential moral role, because they “serve as vehicles through which we express important moral values like respect and consideration for the needs, ideas, and opinions of others”. Stohr frequently invokes Kantian concepts and principles in order to make her point. In Part 2 of this essay, I shall argue that the significance of etiquette is better understood using a virtue ethics framework, like that of (...) Confucianism, rather than the language of Kantianism. Within the Chinese tradition, Daoists have frequently been critics of Confucian ritualism. Consequently, in Part 3, I shall consider some possible Daoist critiques of Stohr’s work. (shrink)

Personal Values is a delightful and enlightening read. It is teeming with novel insights, ground-breaking distinctions, rich examples, new delineations of the field, refreshing historical reminders, inventive arguments, unprecedented connections, identifications of neglected difficulties, and pioneering proposals. I shall focus here on three of these insights, which are illustrative of the pervasive scrupulousness and inventiveness of the book. The first is that there is a distinction between the supervenience base of values and their constitutive grounds. The second is that FA (...) is admittedly circular (because pro-attitudes have values as formal objects), but that this circularity is benign. The third proposal is that one important kind of for- someome-sake’s attitude⎯prototypically, love⎯is such that it is not justified by the properties it represents its object as exemplifying. This is a small sample of claims not meant to be representative of the book. The reason I have chosen to discuss these in particular is that, while finding them plausible and significant, I believe that each raises a worry that Rønnow-Rasmussen fails to address properly. I shall tentatively suggest a possible solution in each case. (shrink)

I gave the name “R theory of time " to the Buddhist philosophy of time in my 2005 article in The 'Indian International Journal of Buddhist Studies because after studying the currently discussed non Buddhist philosophies of time that have been offered to us by many physicists and analytic philosophers, I found that they seemed to not agree as much as I thought theories of time should with the findings of quantum physicists. Rather, the non Buddhist philosophies of time seemed (...) to only be in agreement with relativistic physics, but not at all in agreement with quantum physics. But on the other hand, it seemed to me that the Buddhist philosophy of time agreed best with quantum theory, and thus I published an article about the Buddhist philosophy of time in order to try to show why. (shrink)

In this short piece, I respond to Brian R. Clack's review of my book, Wittgenstein within the Philosophy of Religion.

A longish (12 page) discussion of Richard Sorabji's excellent book, with a further discussion of what it means for a theory of emotions to be a cognitive theory.

Philosophy and economics of Malthusianism. An optimistic view of human population growth and a critique of The Club of Rome and Paul R. Ehrlich, author of The Population Bomb. I apply Julian Simon's perspective to the malthusian debate, inspired by his book The Ultimate Resource. When a child is born he brings into existence not just an extra mouth to feed, but two hands and - more importantly in the long run - an extra brain with which to solve any (...) problems that an increase in population brings. In the long run, and given enough freedom, there in a propensity for humans to produce more than they consume. We are not just like flies in a bottle with a limited amount of resources, but creative creatures that can in principle engage in continual, never ending economic growth. -/- More Info: Multiple publishers: National Review; Clashing Views on Controversial Social Issues; Libertarian Alliance, UK. (shrink)

The title of Kastner’s article is “Beyond Complementarity” (R. E. Kastner 6 March 2016 Foundations of Physics Group, University of Maryland, College Park, USA) -/- In this paper, there are quite many ideas similar to my ideas. The main ideas are the following: -/- - Bohr’s complementarity does not work: “’Complementarity’ cannot consistently account for the emergence of classicality from the quantum level (p. 1) - It is argued that ultimately this problem arises from Bohr’s implicit assumption that all quantum (...) evolution is unitary; i.e., that there is no real, physical non-unitary collapse. (p. 1) -/- In my works 2002-2008 and later (2010-2106), I argued exactly the same ideas. The non-unitary phenomena in quantum and in the relationship between quantum and classical phenomena means exactly the EDWs! -/- Our world of experience is clearly classical in that we can legitimately consider our lab and macroscopic measuring instruments as inhabiting a well-defined inertial frame. But these are the very phenomena that cry out for explanation in view of that fact that the microscopic quantum objects upon which we experiment, according to the theory describing them, do not inhabit well-defined reference frames. (pp. 3-4) -/- “Our world of experience” means exactly the macro-EW vs. the micro-EW. However, we have to pay attention that “quantum world” means the micro-EW (for particles) and the wave-EW. In section 4, Kastner investigates the “unnecessary” Bohr’s “epistemological and methodological assumptions”. If the reader will read the entire section will have the sensation of reading one of my works! In 2007, and 2008, I analyzed exactly the same notions with almost the same verdict! (shrink)

Conspectus of part of John R. Smythies' Analysis of Perception (1956). It presents a summary of his ideas on phenomenal space – the space of one’s imagination, dreams, psychedelic experiences, somatic sensations, visions, hynagogia, etc. – and its relation to physical space.

Conspectus of part of John R. Smythies' Analysis of Perception (1956). It presents a summary of his ideas on phenomenal space – the space of one’s imagination, dreams, psychedelic experiences, somatic sensations, visions, hynagogia, etc. – and its relation to physical space.

This article aims to explore the philosophical meaning of pregnancy and maternity in the writ-ings of R. Soloveitchik and Emmanuel Lévinas. They both make a phenomenological enquiry into these phenomena, by looking on the biological aspect and the emotional aspects. R. Solove-itchik suggests a spiritual interpretation concerning the meaning of pregnancy, which is both biological and spiritual. He attempts to differentiate between the natural parenthood and the spiritual parenthood. Lévinas gives us the philosophical observation through the phenomenolog-ical research of pregnancy, (...) motherhood and parenthood. For him, this inquiry may be revealed as an ethical occurrence that demand responsibility. Perhaps this is one of the unique dimensions of modern Jewish philosophy, looking towards the religious texts with modern philosophical method and modern philosophy theories. Reading carefully the biblical story of Genesis on the notion of birth and maternity, raises textual questions and cultural questions. For Lévinas and R. Soloveitchik these questions can open the door to new philosophical inquiry. (shrink)

Este artículo se opone a la tesis recientemente sostenida por John Searle según la cual no existen los derechos humanos positivos. Argumentamos que la existencia de dichos derechos no es contradictoria, como pretende Searle, con las nociones de "derecho" y"derechos humanos" definidas en su ontología social. Por consiguiente, es posible aceptar la ontología social de Searle y afirmar al mismo tiempo que los derechos humanos positivos existen. En segundo lugar, ofrecemos razones para cuestionar la supuesta prioridad lógica de una ontología (...) social al modo en que Searle la entiende (esto es, como una empresa puramente analítica) sobre los desarrollos más específicos de la filosofía moral, social y política. Al contrario, sugerimos que, por lo que se refiere a la realidad social, los compromisos ontológicos dependen de los presupuestos sustantivos que se adopten en relación con la naturaleza y los fines de la sociedad misma, o bien no pasarán de ser un formalismo vacío sin relevancia heurística alguna. [This paper challenges the point recently made by John Searle that there are no positive human rights. We contend that the existence of positive human rights is not inconsistent, as Searle argues, with the notions of "right" and "human rights" as defined in his social ontology. Therefore, one could adhere to Searle's social ontology and assert the existence of positive human rights at the same time. Subsequently, the paper gives reason to question the alleged logical priority of social ontology in Searle's sense (i.e., as a purely analytic endeavour) over the particular developments of moral, social, and political philosophy. We suggest, on the contrary, that concerning social reality ontological commitments are dependent on substantive assumptions about the nature and aims of society itself, or else they amount to an empty formalism with no heuristic relevance.]. (shrink)

The Cambridge Descartes’ Meditations—A Critical Guide, a recent addition to the numerous companion texts, guidebooks, introductions and commentaries already available, aims to provide novel approaches to important themes of Descartes’ Meditations by combining contextualism and analysis (of arguments). Organized in four parts (Skepticism, Substance and Cause, Sensations, and The Human Being), the volume contains contributions from (mainly) established scholars of Early Modern Philosophy.

The aim of this paper is to present and analyse legal acts cited in the European Parliament resolution of 20 January 2011 on the situation of Christians in the context of freedom of religion. The author presents the substance of the right to religious freedom and the position of religious freedom among other human rights. The paper also shows the formation of European law on religious freedom and grasps the development trends in this area. Because of the discrepancies that arise (...) when translating the same foreign terms into the Polish language, in order to better explain the content of the cited documents, the texts are also given in English language. The article is the summary of basic legal regulations relevant to reflect on religious freedom at EU level. Compiled materials may be useful to continue the reflection on religious freedom. (shrink)

A case to be taken up by the Criminal Appeals Commission because the decision of the appeal court was flawed- a miscarriage of justice against Dr Stephen Hamilton, formerly, a most respected senior family general practitioner.