In Philosophical Investigations §244, Wittgenstein suggests that we understand avowals (first-person psychological utterances) as manifestations or expressions of the speaker's mental states. An interesting philosophical theory, called expressivism, then develops from this Wittgensteinian idea. However, neo-expressivists disagree with simple expressivists on whether avowals are at the same time assertions, which are truth-evaluable. In this paper, I pursue the expressivist debate about whether avowals must also be viewed as assertions. I consider and reject three neo-expressivist objections against simple expressivism. Then, I (...) offer my own account of why we should understand avowals as assertions. (shrink)

Relational egalitarians claim that a situation is just only if everyone it involves relates to one another as equals. It implies that relational egalitarians believe the ideal of “living as equals” (for short) is desirable, and furthermore, necessary for justice. In this paper, I distinguish three accounts of the desirability of the ideal: the instrumental value account, the non‐instrumental value account, and the non‐consequentialist account. I argue that the former two accounts cannot provide satisfying reasons for being a relational egalitarian. (...) Instead, the ideal of “living as equals” ought to be understood as fundamentally a moral requirement in a non‐consequentialist sense. In addition, a pluralist (though fundamentally non‐consequentialist) approach is welcome. (shrink)

In Authority and Estrangement, Richard Moran provides a fascinating account of how we know what we believe that he calls the “transparency account.” This account relies on the transparency relation between the question of whether we believe that p and the question of whether p is true. That is, we can consider the former by considering the grounds for the latter. But Moran’s account has been criticized by David Finkelstein, who argues that it fails to explain how we know our (...) attitudes and emotions more generally. The aim of this paper is to show how Moran’s transparency account can be extended to meet this criticism by modifying it, using insights from Davidson’s view on attitudes and emotions. (shrink)

The current humanitarian use of drones is focused on two applications: disaster mapping and medical supply delivery. In response to the growing interest in drone deployment in the aid sector, we sought to develop a resource to support value sensitivity in humanitarian drone activities. Following a bottom-up approach encompassing a comprehensive literature review, two empirical studies, a review of guidance documents, and consultations with experts, this work illuminates the nature and scope of ethical challenges encountered by humanitarian organizations embarking upon (...) innovation programmes. The Framework for the Ethics Assessment of Humanitarian Drones (FEAHD) identifies five values and five key questions related to ethical considerations along the decision chain of humanitarian drone activities. It fills a gap between high-level, principle-based guidance related to humanitarian innovation, and detailed operation-oriented checklists for projects involving the use of drones. In this way, the FEAHD contributes to support value sensitivity in the humanitarian use of drones. (shrink)

The problem of Free Will is an important topic in religion, philosophy and neuroscience. We will introduce a new model of free will: free choice under constraints. Under outer and inner constraints, human still have the ability of free choice. Outer constrains include physical rules, environment and so on. Inner constrains include customs, desires, habits, preferences and so on. Given a specific context, human have the ability of deciding Yes/No on a specific preference. The free choices are caused, but not (...) determined, by the outer and inner constraints. In addition, the free choices will refashion the inner constraints. Preferences are gradually formed by human, thus they may be gradually de-formed by human. Human can keep the positive preferences, while de-form the negative preferences. When we de-form the negative preferences, we have the chance to pursue another new possibility. So are scientists. They can keep the positive aspects of the known theory, while eliminate the negative aspects. When they eliminate the negative aspects of old conceptual schema, they have the chance to pursue another new conceptual schema. (shrink)

In Zettel, Wittgenstein considered a modified version of Cantor’s diagonal argument. According to Wittgenstein, Cantor’s number, different with other numbers, is defined based on a countable set. If Cantor’s number belongs to the countable set, the definition of Cantor’s number become incomplete. Therefore, Cantor’s number is not a number at all in this context. We can see some examples in the form of recursive functions. The definition "f(a)=f(a)" can not decide anything about the value of f(a). The definiton is incomplete. (...) The definition of "f(a)=1+f(a)" can not decide anything about the value of f(a) too. The definiton is incomplete.<br><br>According to Wittgenstein, the contradiction, in Cantor's proof, originates from the hidden presumption that the definition of Cantor’s number is complete. The contradiction shows that the definition of Cantor’s number is incomplete. <br><br>According to Wittgenstein’s analysis, Cantor’s diagonal argument is invalid. But different with Intuitionistic analysis, Wittgenstein did not reject other parts of classical mathematics. Wittgenstein did not reject definitions using self-reference, but showed that this kind of definitions is incomplete.<br><br>Based on Thomson’s diagonal lemma, there is a close relation between a majority of paradoxes and Cantor’s diagonal argument. Therefore, Wittgenstein’s analysis on Cantor’s diagonal argument can be applied to provide a unified solution to paradoxes. (shrink)

The grue paradox, also called the new riddle of induction, posed a great challenge to the common understanding about induction. This paper shows that there is a close relation between the grue paradox and the problem of conditionals. This paper presents a general form of the grue predicate. Based on the general form, this paper argues that this kind of predicates can not be used for induction and prediction.

Presentism usually holds that only present entities exist. In contrast to presentism, eternalism holds that past, present, and future entities all exist. According to some philosophers, presentism is intuitively incompatible with time travel. In this paper, I defend the compatibility between presentism and time travel by arguing for a plausible account of causation in the presentist framework. To achieve my goal, I respond to an objection to presentist time travel that is based on the nonexistence of the past: the Causation (...) Objection. According to the Causation Objection, causal relations between objects at different times are necessary for time travel, but these are impossible for presentists. I evaluate a possible reply based on a non-relational account of causation and show that this reply is not satisfying. Subsequently, I put forward a fact-based account of causal relation. I argue that presentists could accept facts instead of events as causal relata, thus establishing causal relations. As all facts about the past, the present, and the future exist in the present, we could explain how backward causation works and describe the discrepancy between personal time and external time in presentist time travel; in this way, I argue, we could vindicate the compatibility between presentism and time travel. (shrink)

I consider the intertextuality between Chinese and Western thought by exploring how images, metaphors, and ideas from the texts associated with Zhuangzi and Laozi were appropriated in early twentieth-century German philosophy. This interest in “Lao-Zhuang Daoism” encompasses a diverse range of thinkers including Buber and Heidegger. I examine how the problematization of utility, usefulness, and “purposiveness” in Zhuangzi and Laozi becomes a key point for their German philosophical reception; how it is the poetic character of the Zhuangzi that hints (...) at an appropriate response to the crisis and loss of meaning that characterizes technological modernity and its instrumental technological rationality; that is, how the “poetic” and “spiritual” world perceived in Lao-Zhuang thought became part of Buber's and Heidegger's critical encounter and confrontation with technological modernity; and how their concern with Zhuangzi does not signify a return to a dogmatic religiosity or otherworldly mysticism; it anticipates a this-worldly spiritual or poetic way of dwelling immanently within the world. (shrink)

I present an affirmation of nothingness in the humor of Zhuang Zi 莊子. This essay begins with two images that present a playful transgression of perspectives: the butterfly dream and the discussion over the Hao river. I dwell on these transgressions to highlight the challenge for each to question one’s perspectives and to shift its grounding from epistemic to aesthetic value. Such a sensitivity suggests a mindfulness of the transformation of things 物化. This reinforces reality’s ephemerality, and I, following (...) David Chai, point what lies behind this as the non-being of nothingness 無無. The centrality of the Dao 道 qua nothingness is mirrored by a Daoist who becomes sensitive to the transformation of things and who ultimately undercomes reality, i.e., decenters oneself. This type of existence is what it means to be zhenuinly 真 pretending, which Zhuang Zi does, manifested by the humor in his work. (shrink)

The thorny problem, which we are confronted with in translating the term of “Sein”(Being) from western Philosophy into Chinese, highlights the ambiguity, paradoxy and vagueness of the issue of Sein from a specific viewpoint. Although there is no exact equivalent in Chinese for the word of “Sein”, we use several different words to express the meanings consisted in the issue of “Sein”. By comparison we may find that what is discussed by Zhuang Zi using the terms of “Shi” and (...) “Fei” are just in a considerable degree the same issue discussed by Heidegger using the terms of “Sein” and “Dasein”. However, they gave different opinions to the issue, which show their divergence in their philosophic thinking. (shrink)

Not only defi ning the nature of schizophrenia, but even defi ning schizophrenia as a diagnostic entity is still a challenge for psychiatry. The current diagnostic systems and the related approach to psychopathology are of little aid to this purpose, and have inadvertently resulted in an impoverished clinical practice. There is substantial meaning underlying schizophrenic symptoms that would appear bizarre and senseless from the viewpoint of a purely descriptive method. Psychiatry needs to devise an approach that embraces the (...) complexity of the different perspectives of explanation and understanding of mental illness, examining the interplay of each element in the subjective experience. Symptoms such as delusion and hallucinations cannot merely be conceptualized as false judgment or lacking of external object, respectively, as they refl ect the fact that patients try to make sense of their different, globally altered experience of the self, of others and of the world. This line of reasoning builds on previous work in the phenomenological tradition postulating a disturbance in sensorimotor processes, which bond human beings with one another while remaining imperceptible to consciousness. This suggestion is consistent with a large body of research highlighting impairment in sensory processing in schizophrenia. Other authors underscored the importance of subtle alterations of functions other than sensorimotor processes, such as experiential anomalies of affectivity, cognition-perception and body-motor experience, alterations of self-awareness, and disturbances in reciprocal attunement leading to disconnection from a common register of meanings and loss of common sense. Heidegger refers to a human being as Being intrinsically selfrevelatory in the unity of physis and logos. He refers to the lived experience of being constantly in the everyday situation as being located, “thrown” into the world. The existence is always ‘in the world’, ‘near the things’ and ‘with the others’ for everybody, in the ways of ‘attunement’, ‘understanding’ and ‘discourse’, that are always together, in the unity of the Dasein. This conception of human existence may help understand the subjective experience of a schizophrenic patient and increase diagnostic accuracy and treatment adequacy. (shrink)

I discuss the methodological passage in the begin- ning of Ethica Eudemia I.6 (1216b26-35), which has received attention in connection with Aristotle’s notion of dialectic and his methodology in Ethics. My central focus is not to discuss whether Aristotle is prescribing and using what has been called the method of endoxa. I will focus on how this passage coheres with the remaining parts of the same chapter, which also are advancing methodological remarks. My claim is that the meth- od (...) of Ethica Eudemia I.6 is in agreement with many features of Aristotle’s theory of explanation as presented in the Posterior Analytics: Aristotle’s main concern is a warning against misuses of explanatory arguments. (shrink)

Since 2002 we have been testing and refining a methodology for ontology development that is now being used by multiple groups of researchers in different life science domains. Gary Merrill, in a recent paper in this journal, describes some of the reasons why this methodology has been found attractive by researchers in the biological and biomedical sciences. At the same time he assails the methodology on philosophical grounds, focusing specifically on our recommendation that ontologies developed for scientific purposes should be (...) constructed in such a way that their terms are seen as referring to what we call universals or types in reality. As we show, Merrill’s critique is of little relevance to the success of our realist project, since it not only reveals no actual errors in our work but also criticizes views on universals that we do not in fact hold. However, it nonetheless provides us with a valuable opportunity to clarify the realist methodology, and to show how some of its principles are being applied, especially within the framework of the OBO (Open Biomedical Ontologies) Foundry initiative. (shrink)

The current informal practice of pharmacometrics as a combination art and science makes it hard to appreciate the role that informatics can and should play in the future of the discipline and to comprehend the gaps that exist because of its absence. The development of pharmacometric informatics has important implications for expediting decision making and for improving the reliability of decisions made in model-based development. We argue that well-defined informatics for pharmacometrics can lead to much needed improvements in the efficiency, (...) effectiveness, and reliability of the pharmacometrics process. The purpose of this paper is to provide a description of the pervasive yet often poorly appreciated role of informatics in improving the process of data assembly, a critical task in the delivery of pharmacometric analysis results. First, we provide a brief description of the pharmacometric analysis process. Second, we describe the business processes required to create analysis-ready data sets for the pharmacometrician. Third, we describe selected informatic elements required to support the pharmacometrics and data assembly processes. Finally, we offer specific suggestions for performing a systematic analysis of existing challenges as an approach to defi ning the next generation of pharmacometric informatics. (shrink)

The introductory personal remarks refer to my motivations for choosing research projects, and for moving from physics to molecular biology and then to development, with Hydra as a model system. Historically, Trembley’s discovery of Hydra regeneration in 1744 was the begin¬ning of developmental biology as we understand it, with passionate debates about preformation versus de novo generation, mechanisms versus organisms. In fact, seemingly conflicting bottom-up and top-down concepts are both required in combination to understand development. In modern terms, this (...) means analysing the molecules involved, as well as searching for physical principles underlying development within systems of molecules, cells and tissues. During the last decade, molecular biology has provided surprising and impressive evidence that the same types of mol¬ecules and molecular systems are involved in pattern formation in a wide range of organisms, including coelenterates like Hydra, and thus appear to have been “invented” early in evolution. Likewise, the features of certain systems, especially those of developmental regulation, are found in many different organisms. This includes the generation of spatial structures by the interplay of self-enhancing activation and “lateral” inhibitory effects of wider range, which is a main topic of my essay. Hydra regeneration is a particularly clear model for the formation of defined patterns within initially near-uniform tissues. In conclusion, this essay emphasizes the analysis of development in terms of physical laws, including the application of mathematics, and insists that Hydra was, and will continue to be, a rewarding model for understanding general features of embryogenesis and regeneration. -/- -/- . (shrink)

A fundamental problem in science is how to make logical inferences from scientific data. Mere data does not suffice since additional information is necessary to select a domain of models or hypotheses and thus determine the likelihood of each model or hypothesis. Thomas Bayes’ Theorem relates the data and prior information to posterior probabilities associated with differing models or hypotheses and thus is useful in identifying the roles played by the known data and the assumed prior information when making inferences. (...) Scientists, philosophers, and theologians accumulate knowledge when analyzing different aspects of reality and search for particular hypotheses or models to fit their respective subject matters. Of course, a main goal is then to integrate all kinds of knowledge into an all-encompassing worldview that would describe the whole of reality. A generous description of the whole of reality would span, in the order of complexity, from the purely physical to the supernatural. These two extreme aspects of reality are bridged by a nonphysical realm, which would include elements of life, man, consciousness, rationality, mental and mathematical abstractions, etc. An urgent problem in the theory of knowledge is what science is and what it is not. Albert Einstein’s notion of science in terms of sense perception is refined by defining operationally the data that makes up the subject matter of science. It is shown, for instance, that theological considerations included in the prior information assumed by Isaac Newton is irrelevant in relating the data logically to the model or hypothesis. In addition, the concepts of naturalism, intelligent design, and evolutionary theory are critically analyzed. Finally, Eugene P. Wigner’s suggestions concerning the nature of human consciousness, life, and the success of mathematics in the natural sciences is considered in the context of the creative power endowed in humans by God. (shrink)

Man essentially is a being who pursues meaning and love. How is it possible that today, the concept of man as the rational economic man dominates the current human stage of thought? Why and how has this concept of man taken precedence over the Platonic description? What has made for the triumph of Homo oeconomicus? What has happened to the human race since money has vanquished beauty as the defining essence of humanity? What does it mean that Plato’s ideas sound (...) so alien to us now, so far-fetched, when to the Athenians, they made perfect sense? What does it mean that contemporary man would consider it to be absurd to define the motivating drive of the human being as being led by Eros to the pursuit of beauty when to the ancient Athenians it would be absurd to define the motivating drive of the human being as being led by the goal of the maximization of profit? (shrink)

Pseudohallucinations have remained a contentious phenomenon in clinical psychopathology. Here following a review of the history and current conceptualisation on pesudohallucinations, they have been critically reviewed with regards to their defining characteristics especially their quality, location and patient’s insight into them. It is argued that the insight and location criterion are not able to distinguish pseudohallucinations from hallucinations. The quality of the perception is a better guide in this distinction.