Proponents of ontic conceptions of explanation require all explanations to be backed by causal, constitutive, or similar relations. Among their justifications is that only ontic conceptions can do justice to the ‘directionality’ of explanation, i.e., the requirement that if X explains Y , then not-Y does not explain not-X . Using topological explanations as an illustration, we argue that non-ontic conceptions of explanation have ample resources for securing the directionality of explanations. The different ways in which neuroscientists rely (...) on multiplexes involving both functional and anatomical connectivity in their topological explanations vividly illustrate why ontic considerations are frequently (if not always) irrelevant to explanatory directionality. Therefore, directionality poses no problem to non-ontic conceptions of explanation. (shrink)

In “What Makes a Scientific Explanation Distinctively Mathematical?” (2013b), Lange uses several compelling examples to argue that certain explanations for natural phenomena appeal primarily to mathematical, rather than natural, facts. In such explanations, the core explanatory facts are modally stronger than facts about causation, regularity, and other natural relations. We show that Lange's account of distinctively mathematical explanation is flawed in that it fails to account for the implicit directionality in each of his examples. This inadequacy is remediable in (...) each case by appeal to ontic facts that account for why the explanation is acceptable in one direction and unacceptable in the other direction. The mathematics involved in these examples cannot play this crucial normative role. While Lange's examples fail to demonstrate the existence of distinctively mathematical explanations, they help to emphasize that many superficially natural scientific explanations rely for their explanatory force on relations of stronger-than-natural necessity. These are not opposing kinds of scientific explanations; they are different aspects of scientific explanation. (shrink)

Eternalists believe that there is no ontological difference between the past, present and future. Thus, a challenge arises: in virtue of what does time have a direction? Some eternalists, Oaklander and Tegtmeier ) argue that the direction of time is primitive. A natural response to positing primitive directionality is the suspicion that said posit is too mysterious to do any explanatory work. The aim of this paper is to relieve primitive directionality of some of its mystery by offering (...) a novel way to understand the phenomenon in terms of the recently popularised notion of grounding. (shrink)

Maureen Donnelly has recently argued that directionalism, the view that relations have a direction, applying to their relata in an order, is unable to properly treat certain symmetric relations. She alleges that it must count the application of such a relation to an appropriate number of objects in a given order as distinct from its application to those objects in any other ordering of them. I reply by showing how the directionalist can link the application conditions of any fixed arity (...) relation, no matter its arity or symmetry, and its converse(s) in such a way that directionalism will yield the correct ways in which it can apply. I thus establish that directionalism possesses the same advantage Donnelly's own account of relations, relative positionalism, has over traditional positionalist accounts of relations, which do not properly treat symmetric relations. I then note some advantages that directionalism has over its closest competitors. This includes Donnelly's relative positionalism, since directionalism is not, like relative positionalism, committed to the involvement of relative properties in every irreducibly relational claim. I close by conceding that, as Donnelly notes, directionalism is committed to the primitive relation of order-sensitive relational application. But I don't find this notion as mysterious as Donnelly does. I conclude that, even if one construes this feature of directionalism as a drawback, the two views are at worst at a draw, other things being equal, since this drawback is mitigated by the advantage directionalism has over relative positionalism. (shrink)

These are the first two chapters from a monograph (The Time Flow Manifesto, Holster, 2013-14; unpublished), defending the concepts of time directionality and time flow in physics and naturalistic metaphysics, against long-standing attacks from the ‘conventional philosophy of physical time’. This monograph sets out to disprove twelve specific “fallacies of the conventional philosophy”, stated in the first section below. These are the foundational principles of the conventional philosophy, which developed in the mid-C20th from positivist-inspired studies. The first chapter begins (...) by re-presenting the basic analysis of time reversal symmetry in the context of probabilistic or non-deterministic processes, removing the first critical error in the conventional account. The second chapter argues for a law-like explanation of physical time asymmetry and irreversibility, and shows how the ‘reversibility paradoxes’ are explained. (shrink)

Bertrand Russell famously argued that causation is not part of the fundamental physical description of the world, describing the notion of cause as “a relic of a bygone age”. This paper assesses one of Russell’s arguments for this conclusion: the ‘Directionality Argument’, which holds that the time symmetry of fundamental physics is inconsistent with the time asymmetry of causation. We claim that the coherence and success of the Directionality Argument crucially depends on the proper interpretation of the ‘ (...) time symmetry’ of fundamental physics as it appears in the argument, and offer two alternative interpretations. We argue that: if ‘ time symmetry’ is understood as the time -reversal invariance of physical theories, then the crucial premise of the Directionality Argument should be rejected; and if ‘ time symmetry’ is understood as the temporally bidirectional nomic dependence relations of physical laws, then the crucial premise of the Directionality Argument is far more plausible. We defend the second reading as continuous with Russell’s writings, and consider the consequences of the bidirectionality of nomic dependence relations in physics for the metaphysics of causation. (shrink)

This is Part 2 of a four part paper, intended as an introduction to the key concepts and issues of time directionality for physicists and philosophers. It redresses some fundamental confusions in the subject. These need to be corrected in introductory courses for physics and philosophy of physics students. Here we analyze the quantum mechanical time reversal operator and the reversal of the deterministic Schrodinger equation. It is argued that quantum mechanics is anti-symmetric w.r.t. time reversal in its deterministic (...) laws. This contradicts the orthodox analysis, found throughout the conventional literature on physical time, which claims that quantum mechanics is time symmetric (reversible), and that we must adopt the anti-unitary operator (T*) instead of the unitary time reversal operator (T) for time reversal in quantum mechanics. This is widely claimed as settled scientific fact, and large metaphysical conclusions about the symmetry of time are drawn from it. But it is an error. (shrink)

To explain the correct libertarian approach to immigration, a thought-experiment posits a minimal-state libertarian UK and then the introduction of several relevant anti-libertarian policies with their increasingly disastrous effects. It is argued that the reverse of these imagined policies, as far as is politically possible, must be the correct way forward. This framing is intended to counter the tendency for many articles to misapply libertarian principles to the current messy situation on the mistaken assumption that a state need only stop (...) interfering without rectifying or adjusting for its previous interferences. The relevant parts of various open-border texts are then criticised in light of this and for other errors, in particular for overlooking the likely huge scale of immigration as indicated by Gallup surveys. Additional criticisms are addressed in footnotes throughout. The conclusion outlines three broad options on immigration and suggests that directionally-libertarian policies are both more libertarian and practical than having states open their borders. The readers that might be interested in this subject matter include those engaging in libertarian philosophy, economics, and political theory. (shrink)

This is Part 1 of a four part paper, intended to redress some of the most fundamental confusions in the subject of physical time directionality, and represent the concepts accurately. There are widespread fallacies in the subject that need to be corrected in introductory courses for physics students and philosophers. We start in Part 1 by analysing the time reversal symmetry of quantum probability laws. Time reversal symmetry is defined as the property of invariance under the time reversal transformation, (...) T: t --> -t. It is shown that quantum mechanics (classical or relativistic) is strongly time asymmetric in its probability laws. This contradicts the orthodox analysis, found throughout the conventional literature on physical time, which claims that quantum mechanics is time symmetric or reversible. This is widely claimed as settled scientific fact, and large philosophical and scientific conclusions are drawn from it. But it is an error. The fact is that while quantum mechanics is widely claimed to be reversible on the basis of two formal mathematical properties (that it does have), these properties do not represent invariance under the time reversal transformation. A recent experiment (Batalhão at alia, 2015) showing irreversibility of quantum thermodynamics is discussed as an illustration of this result. Most physicists remain unaware of the errors, decades after they were first demonstrated. Orthodox specialists in the philosophy of time who are aware of the error continue to refer to the ‘time symmetry’ or ‘reversibility’ of quantum mechanics anyway – and exploit the ambiguity to claim false implications about physical time reversal symmetry in nature. The excuse for perpetrating the confusion is that, since it is has now become customary to refer to the formal properties of quantum mechanics as ‘reversibility’ or ‘time reversal symmetry’, we should just keep referring to them by this name, even though they are not time reversal symmetry. This causes endless confusion, in attempts to explain the physical irreversibility of our universe, and in philosophical discussions of implications of physics for the nature of time. The failure of genuine time reversal symmetry in quantum mechanics changes the interpretation of modern physics in a deep way. It changes the problem of explaining the real irreversibility found throughout nature. (shrink)

Lange argues that some natural phenomena can be explained by appeal to mathematical, rather than natural, facts. In these “distinctively mathematical” explanations, the core explanatory facts are either modally stronger than facts about ordinary causal law or understood to be constitutive of the physical task or arrangement at issue. Craver and Povich argue that Lange’s account of DME fails to exclude certain “reversals”. Lange has replied that his account can avoid these directionality charges. Specifically, Lange argues that in legitimate (...) DMEs, but not in their “reversals,” the empirical fact appealed to in the explanation is “understood to be constitutive of the physical task or arrangement at issue” in the explanandum. I argue that Lange’s reply is unsatisfactory because it leaves the crucial notion of being “understood to be constitutive of the physical task or arrangement” obscure in ways that fail to block “reversals” except by an apparent ad hoc stipulation or by abandoning the reliance on understanding and instead accepting a strong realism about essence. (shrink)

Purpose This article aims to gain a better understanding of the reasons why serendipity is designed for in different kinds of environments. Understanding these design intents sheds light on the value such designs bring to designers, in contrast to the users of the environment. In this way, the article seeks to contribute to the literature on cultivating serendipity from a designers’ point of view. -/- Design/methodology/approach An extensive review of the literature discussing designing for serendipity was conducted to elicit the (...) different motivations to design for serendipity. Based on these findings and a thorough analysis, a typology of design intents for serendipity is presented. -/- Findings The article puts forward four intents to design for serendipity: serendipity as an ideal, common good, mediator and feature. It also highlights that the current academic discourse puts a strong emphasis on two of them. It is argued that this academic abstraction could be problematic for how we deal with designs for serendipity, both in theory and practice. -/- Originality/value The novelty of this article is that it addresses the question of why to design for serendipity from a designer’s point of view. By introducing the notion of directionality it opens up the opportunity to discuss serendipity from multiple perspectives, which contributes to gaining a firmer understanding of serendipity. It allows to more explicitly formulate the different functions of a design for serendipity and thereby expands our knowledge on the value of designing for serendipity. At the same time, it sheds light on the potential threats to designing for serendipity. (shrink)

What would it be for a process to happen backwards in time? Would such a process involve different causal relations? It is common to understand the time-reversal invariance of a physical theory in causal terms, such that whatever can happen forwards in time can also happen backwards in time. This has led many to hold that time-reversal symmetry is incompatible with the asymmetry of cause and effect. This article critiques the causal reading of time reversal. First, I argue that the (...) causal reading requires time-reversal-related models to be understood as representing distinct possible worlds and, on such a reading, causal relations are compatible with time-reversal symmetry. Second, I argue that the former approach does, however, raise serious sceptical problems regarding the causal relations of paradigm causal processes and as a consequence there are overwhelming reasons to prefer a non-causal reading of time reversal, whereby time reversal leaves causal relations invariant. On the non-causal reading, time-reversal symmetry poses no significant conceptual nor epistemological problems for causation. _1_ Introduction _1.1_ The directionality argument _1.2_ Time reversal _2_ What Does Time Reversal Reverse? _2.1_ The B- and C-theory of time _2.2_ Time reversal on the C-theory _2.3_ Answers _3_ Does Time Reversal Reverse Causal Relations? _3.1_ Causation, billiards, and snooker _3.2_ The epistemology of causal direction _3.3_ Answers _4_ Is Time-Reversal Symmetry Compatible with Causation? _4.1_ Incompatibilism _4.2_ Compatibilism _4.3_ Answers _5_ Outlook. (shrink)

An account of distinctively mathematical explanation (DME) should satisfy three desiderata: it should account for the modal import of some DMEs; it should distinguish uses of mathematics in explanation that are distinctively mathematical from those that are not (Baron [2016]); and it should also account for the directionality of DMEs (Craver and Povich [2017]). Baron’s (forthcoming) deductive-mathematical account, because it is modelled on the deductive-nomological account, is unlikely to satisfy these desiderata. I provide a counterfactual account of DME, the (...) Narrow Ontic Counterfactual Account (NOCA), that can satisfy all three desiderata. NOCA appeals to ontic considerations to account for explanatory asymmetry and ground the relevant counterfactuals. NOCA provides a unification of the causal and the non-causal, the ontic and the modal, by identifying a common core that all explanations share and in virtue of which they are explanatory. (shrink)

The work of Gregory Bateson offers a metaphysical basis for a “process psychology,” that is, a view of psychological practice and research guided by an ontology of becoming—identifying change, difference, and relationship as the basic elements of a foundational metaphysics. This article explores the relevance of Bateson's recursive epistemology, his re-conception of the Great Chain of Being, a first-principles approach to defining the nature of mind, and understandings of interaction and difference, pattern and symmetry, interpretation and context. Bateson's philosophical contributions (...) will be drawn into relationship with Wittgenstein's philosophy of language as use, Melnyk's theory of causal levels of explanation, Korzybski's account of map and territory, the rejection of the heuristic rigidity of substantialist ontologies, and a cybernetics communication science-informed approach to contextual bi-directionality of causality. We thereby arrive at an understanding of Bateson's process psychology that, given its ecological-systemic nature, is explanatorily applicable across the mind sciences. This process psychology equips us to answer the question: What is mind? Not by explanatory appeal to substantial entities contained within mind, but instead by recourse to the contextually relevant patterns for understanding mind to a particular purpose. We have thereby attended to the gulf between heuristics and fundamentals, between psychological models and an onto-epistemic account of reality. Insufficient attention has been given to characterising the vital nature of Bateson's philosophical oeuvre to psychological practice. This article draws out Bateson's relevance to establishing foundational principles for a process psychology capable of reinvigorating psychological thought. (shrink)

In the United States today, much interpersonal racism is driven by corrupt forms of self-preservation. Drawing from Jean- Jacques Rousseau, I refer to this as self-love racism. The byproduct of socially-induced racial anxieties and perceived threats to one’s physical or social wellbeing, self-love racism is the protective attachment to the racialized dimensions of one’s social status, wealth, privilege, and/or identity. Examples include police officer related shootings of unarmed Black Americans, anti-immigrant sentiment, and the resurgence of unabashed white supremacy. This form (...) of racism is defined less by the introduction of racism into the world and more on the perpetuation of racially unjust socioeconomic and political structures. My theory, therefore, works at the intersection of the interpersonal and structural by offering an account of moral complacency in racist social structures. My goal is to reorient the directionality of philosophical work on racism by questioning the sense of innocence at the core of white ways-of-being. (shrink)

It is often said that the world is explained by laws of nature together with initial conditions. But does that mean initial conditions don’t require further explanation? And does the explanatory role played by initial conditions entail or require that time has a preferred direction? This chapter looks at the use of the ‘initialness defence’ in physics, the idea that initial conditions are intrinsically special in that they don’t require further explanation, unlike the state of the world at other times. (...) Such defences commonly assume a primitive directionality of time to distinguish between initial and final conditions. Using the case study of the time-asymmetry of thermodynamics and the so-called ‘past hypothesis’ — the hypothesis that the early universe was in a state of very low entropy —, I outline and support a deflationary account of the initialness defence that does not pre- suppose a basic directionality of time, and argue that there is a relevant explanatory asymmetry between initial conditions and the state of systems at other times only if certain causal conditions are satisfied. Hence, the initialness defence is available to those who reject a fundamental direction of time. (shrink)

This article analyzes the view of evolutionary theory as a theory of forces. The analogy with Newtonian mechanics has been challenged due to the alleged mismatch between drift and the other evolutionary forces. Since genetic drift has no direction several authors tried to protect its status as a force: denying its lack of directionality, extending the notion of force and looking for a force in physics which also lacks of direction. I analyse these approaches, and although this strategy finally (...) succeeds, this discussion overlooks the crucial point on the debate between causalists and statisticalists: the causal status of evolutionary theory. (shrink)

This research explores the carnal, experienced self as processual and becoming, situating life as zoe (as per Braidotti) in the context of the Western culture, characterized by alienation (Fromm, Foucault). The study first addresses the ontological disposition of the carnal self and then turns to the concepts of life and death (Freud, Fromm), to explicate the tie between materiality and discourse conditions. Erich Fromm’s classical distinction of having and being is restated as a distinction of having and becoming, which are (...) then explored as complimentary ontological, cultural, and characterological directionalities. A genealogy of their mutual dynamics then allows situating the relations of carnal bodies and inorganic prosthesis (e.g. technologies) in the light of life considered as the necessary synthesis of forces of preservation and perpetual change, beyond subject-object duality. (shrink)

One branch of the responsible innovation literature involves the direction of innovation: if the public or decision-makers can or should direct innovation, how should innovation be directed? This paper explicates a case study where directionality – the plurality of plausible values for innovation – is directly implicated. In this case, a key technology may require a strategy for innovation, but there are contrasting normative reasons to drive that innovation in different ways, reflecting two distinct moral values, ‘effectiveness’ and responsiveness (...) to ‘need’. In this case, carbon dioxide removal, these values may well conflict. Strategically deploying carbon dioxide removal in a cost-effective manner would tend to support siting it in regions where there are significant oil and gas operations. In contrast, strategically deploying carbon dioxide removal in response to need would tend to support siting it in regions where expected demand for the technology is required for development. [Open access]. (shrink)

This book defends a relational theory of the passage of time. The realist view of passage developed in this book differs from the robust, substantivalist position. According to relationism, passage is nothing over and above the succession of events, one thing coming after another. Causally related events are temporally arranged as they happen one after another along observers’ worldlines. There is no unique global passage but a multiplicity of local passages of time. After setting out this positive argument for relationism, (...) the author deals with five common objections to it: (a) triviality of deflationary passage, (b) a-directionality of passage, (c) the impossibility of experiencing passage, (d) fictionalism about passage, and (e) the incompatibility of passage with perduring objects. (shrink)

We argue for asymmetries between positive and negative partiality. Specifically, we defend four claims: i) there are forms of negative partiality that do not have positive counterparts; ii) the directionality of personal relationships has distinct effects on positive and negative partiality; iii) the extent of the interactions within a relationship affects positive and negative partiality differently; and iv) positive and negative partiality have different scope restrictions. We argue that these asymmetries point to a more fundamental moral principle, which we (...) call Morality’s Harmonious Propensity. According to this principle, morality has a propensity toward preserving positive relationships and dissolving negative ones. (shrink)

Why is unpleasant pain bad for us? Evidently because of how it feels. This bit of commonsense is a challenge for well-being perfectionism, since pain doesn’t look anything like failure to fulfill human nature. Here, I sketch a new version of perfectionism that avoids this problem. To explain what is basically good for us, it appeals to the capacities whose functioning defines who we are, or our subjective nature, instead of human nature. I argue that these capacities have a telic (...) structure, so that practical reason, for example, constitutively aims at competently realizing valuable ends that are in harmony. According to telic perfectionism, we do well when such formal aims are realized and badly when they’re frustrated. Crucially, our subjective nature is defined not only by how we reason but also by how we feel. And valenced experience, too, has built-in directionality, according to the most plausible views about the nature of pleasure and pain. The phenomenal character of unpleasant pain is inseparable from its setting for us the end of eliminating itself. As long as we are in pain, then, the formal aim of our self-defining capacity for valenced experience is frustrated. For telic perfectionism, unpleasant pain is thus robustly bad for us, and the explanation of its badness makes essential reference to how it feels. (shrink)

Maxwell’s Demon is a thought experiment devised by J. C. Maxwell in 1867 in order to show that the Second Law of thermodynamics is not universal, since it has a counter-example. Since the Second Law is taken by many to provide an arrow of time, the threat to its universality threatens the account of temporal directionality as well. Various attempts to “exorcise” the Demon, by proving that it is impossible for one reason or another, have been made throughout the (...) years, but none of them were successful. We have shown (in a number of publications) by a general state-space argument that Maxwell’s Demon is compatible with classical mechanics, and that the most recent solutions, based on Landauer’s thesis, are not general. In this paper we demonstrate that Maxwell’s Demon is also compatible with quantum mechanics. We do so by analyzing a particular (but highly idealized) experimental setup and proving that it violates the Second Law. Our discussion is in the framework of standard quantum mechanics; we give two separate arguments in the framework of quantum mechanics with and without the projection postulate. We address in our analysis the connection between measurement and erasure interactions and we show how these notions are applicable in the microscopic quantum mechanical structure. We discuss what might be the quantum mechanical counterpart of the classical notion of “macrostates”, thus explaining why our Quantum Demon setup works not only at the micro level but also at the macro level, properly understood. One implication of our analysis is that the Second Law cannot provide a universal lawlike basis for an account of the arrow of time; this account has to be sought elsewhere. (shrink)

In recent years, there has been a heated debate about how to interpret findings that seem to show that humans rapidly and automatically calculate the visual perspectives of others. In the current study, we investigated the question of whether automatic interference effects found in the dot-perspective task (Samson, Apperly, Braithwaite, Andrews, & Bodley Scott, 2010) are the product of domain-specific perspective-taking processes or of domain-general “submentalizing” processes (Heyes, 2014). Previous attempts to address this question have done so by implementing inanimate (...) controls, such as arrows, as stimuli. The rationale for this is that submentalizing processes that respond to directionality should be engaged by such stimuli, whereas domain-specific perspective-taking mechanisms, if they exist, should not. These previous attempts have been limited, however, by the implied intentionality of the stimuli they have used (e.g. arrows), which may have invited participants to imbue them with perspectival agency. Drawing inspiration from “novel entity” paradigms from infant gaze-following research, we designed a version of the dot-perspective task that allowed us to precisely control whether a central stimulus was viewed as animate or inanimate. Across four experiments, we found no evidence that automatic “perspective-taking” effects in the dot-perspective task are modulated by beliefs about the animacy of the central stimulus. Our results also suggest that these effects may be due to the task-switching elements of the dot-perspective paradigm, rather than automatic directional orienting. Together, these results indicate that neither the perspective-taking nor the standard submentalizing interpretations of the dot-perspective task are fully correct. (shrink)

The neutral theory often is presented as a theory of "noise" or silent changes at an isolated "molecular level", relevant to marking the steady pace of divergence, but not to the origin of biological structure, function, or complexity. Nevertheless, precisely these issues can be addressed in neutral models, such as those elaborated here in regard to scrambled ciliate genes, gRNA-mediated RNA editing, the transition from self-splicing to spliceosomal splicing, and the retention of duplicate genes. All of these are instances of (...) a more general scheme of "constructive neutral evolution" that invokes biased variation, epistatic interactions, and excess capacities to account for a complex series of steps giving rise to novel structures or operations. The directional and constructive outcomes of these models are not due to neutral allele fixations per se, but to these other factors. Neutral models of this type may help to clarify the poorly understood role of non-selective factors in evolutionary innovation and directionality. (shrink)

This article uses phenomenology to examine the way whiteness appears. It begins by discussing the phenomenologies of race done by Linda Martin Alcoff and Sara Ahmed, focusing on their accounts of how race develops and the role that proximity and visibility play in the production of racial categories. It then offers critiques of Ahmed and Alcoff for naturalizing part of the process by which race develops, arguing that a better account of race can be given if we avoid seeing race (...) as a function of proximity or visibility. A stronger account of whiteness can be given if we draw from the work of Merleau-Ponty, in particular his claims that there is always a directionality to perception and that we complete the world in our perceptions of it. A phenomenology that is motivated by these considerations will be able to explain how whiteness is able to appear in so many ways as it is constantly being completed differently in different contexts. The article ends by describing some of these contexts, such as how whiteness is often occluded but can also manifest the qualities of malignancy and autoimmunity. (shrink)

This essay moves along broad lines from molecular biology to evolutionary biology and ecology to theology. Its objectives are to: 1) present some recent scientific findings in the emerging field of epigenetics that indicate that it is “the genome in context,” not genes per se, that are important in biological development and evolution; 2) show that this weakens the gene-centric neo-Darwinist explanation of evolution which, in fact, shares a certain preformationist orientation with intelligent design theory; 3) argue that the evidence (...) against a gene-centric view in no way negates Darwin’s central idea of “descent with modification”; 4) argue that an embrace of the evolutionary story, with all of its contingency and apparent lack of directionality, is not only consistent with Christianity, but actually resonates with the notion of the self-emptying love of God in Jesus Christ; and finally 5) suggest that we are called through an ecological imperative to embrace our evolutionary story, to listen to our “genetic coding,” and to reclaim our grounding as a species in the natural world. Corrigendum (published in later issue of journal): There was an error in the paragraph describing the mode of action of the small temporally-expressed RNAs (stRNAs) lin-4 and let-7 from Caenorhabditis elegans. Instead of reading "These two stRNAs act by binding to the tails of their target messenger RNAs (mRNAs); this results in destruction of the target and an overall drop in the level of production of protein from agouti mRNA" [note that agouti mRNA is not a target of these stRNAs], the sentence should have read, "These two stRNAs act by binding to the tails of target messenger RNAs (mRNAs); this leads to inhibition of translation of the mRNAs into protein and a consequent drop in the levels of the corresponding target protein.". (shrink)

Increasingly, empirically minded moral philosophers are using data from cognitive science and neuroscience to resolve some longstanding philosophical questions about moral motivation, such as whether moral beliefs require the presence of a desire to motivate. These empirical approaches are implicitly committed to the existence of folk psychological mental states like beliefs and desires. However, data from the neuroscience of decision-making, particularly cellular-level work in neuroeconomics, is now converging with data from cognitive and social neuroscience to explain the processes through which (...) agents are moved to act on the basis of decisions, including decisions about social and moral norms. I argue that these developments are beginning to cast doubt on the prospect of finding nontrivial physical 'realizers' for the FP states invoked in the Humeanism dispute by posing two distinctive challenges that tend to work against each other: belief-desire directionality and causal relevance. (shrink)

Schelling’s Principle of Art returns us to an ancient epic sensibility, laying the foundations for reversing the unrealistic ‘modern mythology’ arguably at the core of humanity’s ecological/existential crisis. This contribution examines how, by detailing his systematic approach to constructing art ‘in the particular’ (art-forms/works). ‘Particularity’ is subject only to the reason inherent in the potences (or consequences) of the affirmation of the whole unity (Principle). Hence Schelling’s ‘affirming principles’ determine boundary conditions for his ‘mythological categories’, revealing why their generalities inform (...) a ‘scientific sequence’ for explaining the features of the Formative and Verbal arts (ie., all artforms, ‘for all time’). Examining specific examples shows how Schelling resolves key difficulties (appearance/reality, form/non-form, intentionality, and purpose) for assessing art’s higher meaning-value directionality; why phenomenology is key to understanding it; and how we arrived at the problematic modern ‘epic’ reversal of ancient universalising focusing our attention on ‘efficient’ over ‘final’ causes in art-making/admiring. Explaining practical application of the Principle-in-action expands on why Schelling’s ‘dialectical aesthetics’ presents a hitherto unrecognised radical advance on Kant’s. My conclusion summarises what shifts in attendance to the art object Schelling’s system demands, and why his Philosophy of Art offers a suitable framework for collectively re-worlding the world. (shrink)

The rediscovery of Mendel's laws a century ago launched the science that William Bateson called "genetics," and led to a new view of evolution combining selection, particulate inheritance, and the newly characterized phenomenon of "mutation." This "mutationist" view clashed with the earlier view of Darwin, and the later "Modern Synthesis," by allowing discontinuity, and by recognizing mutation (or more properly, mutation-and-altered-development) as a source of creativity, direction, and initiative. By the mid-20th century, the opposing Modern Synthesis view was a prevailing (...) orthodoxy: under its influence, "evolution" was redefined as "shifting gene frequencies," that is, the sorting out of pre-existing variation without new mutations; and the notion that mutation-and-altered-development can exert a predictable influence on the course of evolutionary change was seen as heretical. Nevertheless, mutationist ideas re-surfaced: the notion of mutational determinants of directionality emerged in molecular evolution by 1962, followed in the 1980s by an interest among evolutionary developmental biologists in a shaping or creative role of developmental propensities of variation, and more recently, a recognition by theoretical evolutionary geneticists of the importance of discontinuity and of new mutations in adaptive dynamics. The synthetic challenge presented by these innovations is to integrate mutation-and-altered-development into a new understanding of the dual causation of evolutionary change--a broader and more predictive understanding that already can lay claim to important empirical and theoretical results--and to develop a research program appropriately emphasizing the emergence of variation as a cause of propensities of evolutionary change. (shrink)

There is almost a consensus among conditional experts that indicative conditionals are not material. Their thought hinges on the idea that if indicative conditionals were material, A → B could be vacuously true when A is false, even if B would be false in a context where A is true. But since this consequence is implausible, the material account is usually regarded as false. It is argued that this point of view is motivated by the grammatical form of conditional sentences (...) and the symbols used to represent their logical form, which misleadingly suggest a one-way inferential direction from A to B. That conditional sentences mislead us into a directionality bias is a phenomenon that is well-documented in the literature about conditional reasoning. It is argued that this directional appearance is deceptive and does not reflect the underlying truth conditions of conditional sentences. This directional bias is responsible for both the unpopularity of the material account of conditionals and some of the main alternative principles and themes in conditional theory, including the Ramsey’s test, the Equation, Adams’ thesis, conditional-assertion and possible world theories. The directional mindset forgets a hard- earned lesson that made classical logic possible in the first place, namely, that grammatical form of sentences can mislead us about its truth conditions. There is a case to be made for a material account of indicative conditionals when we break the domination of words over the human mind. (shrink)

In the framework of Husserl's phenomenology, intentionality is regarded as the main feature of every act of consciousness. Our consciousness is directed towards objects immanent in it, however in a variety of epistemological functions and operations, such as sensory perception, judgment, cognition, volition, imagination, etc. Husserl uses the technical terms noesis and noema to designate the intentional acts of consciousness and their outcome in the constitution of objects in consciousness. At the same time, the persistence of a hyletic data is (...) emphasized, which as pure sense data escapes the phenomenological reduction and remains as such a residuum in the consciousness. In my lecture I try to work out the clear implication of epistemological referentiality in the phenomenological basic notion of intentionality. Among other things, I rely on the conceptual history of intentionality, i. e. on the earlier theories of intentionality in the Middle Ages and the philosophical revival of this notion in the late 19th century by Franz Brentano. Referentiality defines itself as the referential access of consciousness to objects of sensory perception, judgment, cognition, etc., in which the objects form the final referents. In the phenomenological framework, intentionality refers to the intentional access of consciousness to objects irrespective of their consciousness-immanence or -transcendence. The analogy between intentionality and referentiality is therefore based on the act-character as well as the directionality of consciousness which suggests the characteristic attempt of consciousness to gain intentional-referential access to objects. The directionality of consciousness in every intentional act ultimately marks and confirms the referentiality i. e the referential access of consciousness to the object. Intentionality as intentional-referential access to objects becomes a problem, when the access of consciousness to the object proves to be inadequate. I try to show how this problem of referentiality inevitably arises in Husserl's phenomenology of inner time-consciousness, especially in his conception of a time-object (Zeitobjekt). The consciousness-immanence of a time-object, such as a melody, points to a problem, that the intertwining of the temporality of consciousness and that of time-object necessarily results in various aporias of time, as Paul Ricœur observes and discusses in detail in his seminal work Temps et Récit. Moreover, the residual persistence of hyletic data, that survives all phenomenological reductions, would establish an actual interface between consciousness and reality, as Jaakko Hintikka emphasizes in his essay The phenomenological dimension. The aporicity of time refers to the autonomy of time and, thereby, to the autonomy of time-object in its intentional in-existence in consciousness. The hyletic data as interface between consciousness and reality points to the necessary referential extension of consciousness to objects that are otherwise excluded in the context of phenomenology. From these and similar premises, I would like to demonstrate how the problem of referentiality in Husserl's philosophy of time inevitably presupposes a reversion of referentiality within the prevailing noesis-noema structure that underlies the consciousness-immanence of objects. (shrink)

A fundamental problem in understanding the nature of time is explaining its directionality. This 1990 PhD thesis re-examines the concepts of time flow, the physical directionality of time, and the semantics of tensed language. Several novel results are argued for that contradict the orthodox anti-realist views still dominant in the subject. Specifically, the concept of "metaphysical time flow" is supported as a valid scientific concept, and argued to be intrinsic to the directionality of objective probabilities in quantum (...) mechanics; the common claims that quantum probability theory is time reversible is shown to be based on an analytic error, stemming from a false choice for the criterion for reversibility of probabilistic theories (recognized by Satosi Watanabe in the 1950s but ignored in all philosophical discussions); and a consistent semantics for tensed language (adapted from the tree model of Storrs McCall) is constructed, showing that the common rejection of "time flow" as having no meaningful semantics is false. These debates are still ongoing in almost exactly the same state they were pre-1990, and there is appears to be no visible progress in the subject. Critical points made against errors in the orthodox account (which has been sustained for 70 years by the anti-realist philosophy of time, typified by the "Pittsburg School" of Grunbaum-Earman-Norton-Roberts), are still not recognized in the philosophy of time or physics. Some key technical proofs in this thesis have been published in physics proper. See p.ii-iii for full original abstract. (This pdf is uploaded from the Massey University archive.). (shrink)

At the centre of Powers' (2019) China and England is an extraordinary forgotten episode in the history of political ideas. There was a time when English radicals critiqued the corruption and injustice of the English political system by contrasting it with the superior example of China. There was a time when they advocated adopting a Chinese conceptual framework for thinking about politics. So dominant and prevalent was the English radicals' use of this framework, that their opponents took to dismissing their (...) points as 'the argument from the Chinese'. In my review of Powers' book, I welcome the profound reconfiguration of our political understandings that knowledge of this historical episode brings. However, I question Powers' framing presumption that the generic problems of any complex society lead to convergence on a single master political value of 'social justice'. Surely there are deep and enduring differences amongst thinkers of political value, even within a single society, let alone across different societies. Taking this point seriously would challenge the simple linear directionality of Powers' story of moral and political progress. (shrink)