In this paper it is argued that Frankfurt's and Strawson's defenses of compatibilism are insufficient due to neglected features of the role of alternate possibilities in assigning moral responsibility. An attempt is made to locate more adequately the genuine source of tension between free will and determinism, in a crowding phenomenon in the view of an action which our concept of responsibility has not grown up coping with. Finally, an argument is made that due to the nature of belief we (...) can believe the thesis of determinism only if it is false, lending support to incompatibilism. (shrink)

This paper defends the naïve thesis that the method of experiment has per se an epistemic superiority over the method of computer simulation, a view that has been rejected by some philosophers writing about simulation, and whose grounds have been hard to pin down by its defenders. I further argue that this superiority does not come from the experiment’s object being materially similar to the target in the world that the investigator is trying to learn about, as both sides of (...) dispute over the epistemic superiority thesis have assumed. The superiority depends on features of the question and on a property of natural kinds that has been mistaken for material similarity. Seeing this requires holding other things equal in the comparison of the two methods, thereby exposing that, under the conditions that will be specified, the simulation is necessarily epistemically one step behind the corresponding experiment. Practical constraints like feasibility and morality mean that scientists do not often face an other-things- equal comparison when they choose between experiment and simulation. Nevertheless, I argue, awareness of this superiority and of the general distinction between experiment and simulation is important for maintaining motivation to seek answers to new questions. (shrink)

I develop a general framework with a rationality constraint that shows how coherently to represent and deal with second-order information about one's own judgmental reliability. It is a rejection of and generalization away from the typical Bayesian requirements of unconditional judgmental self-respect and perfect knowledge of one's own beliefs, and is defended by appeal to the Principal Principle. This yields consequences about maintaining unity of the self, about symmetries and asymmetries between the first- and third-person, and a principled way of (...) knowing when to stop second-guessing oneself. Peer disagreement is treated as a special case where one doubts oneself because of news that an intellectual equal disagrees. This framework, and variants of it, imply that the typically stated belief that an equally reliably peer disagrees is incoherent, and thus that pure rationality constraints without further substantive information cannot give an answer as to what to do. The framework also shows that treating both ourselves and others as thermometers in the disagreement situation does not imply the Equal Weight view. (shrink)

This paper defends the naïve thesis that the method of experiment has per se an epistemic superiority over the method of computer simulation, a view that has been rejected by some philosophers writing about simulation, and whose grounds have been hard to pin down by its defenders. I further argue that this superiority does not come from the experiment’s object being materially similar to the target in the world that the investigator is trying to learn about, as both sides of (...) dispute over the epistemic superiority thesis have assumed. The superiority depends on features of the question and on a property of natural kinds that has been mistaken for material similarity. Seeing this requires holding other things equal in the comparison of the two methods, thereby exposing that, under the conditions that will be specified, the simulation is necessarily epistemically one step behind the corresponding experiment. Practical constraints like feasibility and morality mean that scientists do not often face an other-things- equal comparison when they choose between experiment and simulation. Nevertheless, I argue, awareness of this superiority and of the general distinction between experiment and simulation is important for maintaining motivation to seek answers to new questions. (shrink)

There is a widespread view that in order to be rational we must mostly know what we believe. In the probabilistic tradition this is defended by arguments that a person who failed to have this knowledge would be vulnerable to sure loss, or probabilistically incoherent. I argue that even gross failure to know one's own beliefs need not expose one to sure loss, and does not if we follow a generalization of the standard bridge principle between first-order and second-order beliefs. (...) This makes it possible for a subject to use probabilistic decision theory to manage in a rational way cases of potential failure of this self-knowledge, as we find in implicit bias. Through such cases I argue that it is possible for uncertainty about what our beliefs are to be not only rationally permissible but advantageous. (shrink)

How confident does the history of science allow us to be about our current well-tested scientific theories, and why? The scientific realist thinks we are well within our rights to believe our best-tested theories, or some aspects of them, are approximately true.2 Ambitious arguments have been made to this effect, such as that over historical time our scientific theories are converging to the truth, that the retention of concepts and claims is evidence for this, and that there can be no (...) other serious explanation of the success of science than that its theories are approximately true. There is appeal in each of these ideas, but making such strong claims has tended to be hazardous, leaving us open to charges that many typical episodes in the history of science just do not fit the model. (See, e.g., Laudan 1981.) Arguing for a realist attitude via general claims – properties ascribed to sets of theories, trends we see in progressions of theories, and claimed links between general properties like success and truth that apply or fail to apply to any theory regardless of its content – is like arguing for or via a theory of science, which brings with it the obligation to defend that theory. I think a realist attitude toward particular scientific theories for which we have evidence can be maintained rationally without such a theory, even in the face of the pessimistic induction over the history of science. The starting point at which questions arise as to what we have a right to believe about our theories is one where we have theories and evidence for them, and we are involved in the activity of apportioning our belief in each particular theory or hypothesis in accord with the strength of the particular evidence.3 The devil’s advocate sees our innocence and tries his best to sow seeds of doubt. If our starting point is as I say, though, the innocent believer in particular theories does not have to play offense and propose sweeping views about science in general, but only to respond to the skeptic’s challenges; the burden of initial argument is on the skeptic.. (shrink)

In the aftermath of Gettier’s examples, knowledge came to be thought of as what you would have if in addition to a true belief and your favorite epistemic goody, such as justifiedness, you also were ungettiered, and the theory of knowledge was frequently equated, especially by its detractors, with the project of pinning down that extra bit. It would follow that knowledge contributes something distinctive that makes it indispensable in our pantheon of epistemic concepts only if avoiding gettierization has a (...) value that can be explained without presupposing the value of knowledge. Tracking-type knowledge has a value that no other logically possible conditions on true belief does. As an Evolutionarily Stable Strategy it preserves appropriate belief states through time and changing circumstances. If we characterize gettierization through the concept of relevance matching, then we see that avoiding gettierization has a value independent of that of knowledge, namely, understanding, and that it is unnecessary to add a clause to the tracking conditions to make them suppress gettierization directly, though fallibly. The bright line of value is between gettierization avoidance and understanding on the one hand and knowledge on the other, and so should be the bright line defining concepts. The concept of relevance matching is key to a definition of what it is to understand why p is true, as opposed merely to knowing that p is true. Perfect tracking implies perfect relevance matching, so knowledge and understanding are intimately connected but understanding also requires that one own states that accomplish the relevance matching rather than achieving it vicariously. The theory of understanding based on relevance matching implies that understanding requires appreciation of not only p but its connections to other matters, and explains how it is possible to know that p is true without understanding why. The view implies that understanding is literally simulation, and is suggestive about understanding other minds. (shrink)

There is much disagreement about how extensive a role theoretical mind-reading, behavior-reading, and simulation each have and need to have in our knowing and understanding other minds, and how each method is implemented in the brain, but less discussion of the epistemological question what it is about the products of these methods that makes them count as knowledge or understanding. This question has become especially salient recently as some have the intuition that mirror neurons can bring understanding of another's action (...) despite involving no higher-order processing, whereas most epistemologists writing about understanding think that it requires reflective access to one's grounds, which is closer to the intuitions of other commenters on mirror neurons. I offer a definition of what it is that makes something understanding that is compelling independently of the context of cognition of other minds, and use it to show two things: 1) that theoretical mind-reading and simulation bring understanding in virtue of the same epistemic feature, and 2) why the kind of motor representation without propositional attitudes that is done by mirror neurons is sufficient for action understanding. I further suggest that more attention should be paid to the potential disadvantages of a simulative method of knowing. Though it can be more efficient in some cases, it can also bring vulnerability, wear and tear on one's personal equipment, and unintended mimicry. (shrink)

Less discussed than Hume’s skepticism about what grounds there could be for projecting empirical hypotheses is his concern with a skeptical regress that he thought threatened to extinguish any belief when we reflect that our reasoning is not perfect. The root of the problem is the fact that a reflection about our reasoning is itself a piece of reasoning. If each reflection is negative and undermining, does that not give us a diminution of our original belief to nothing? It requires (...) much attention to detail, we argue, to determine whether or not there is a skeptical problem in this neighborhood. Consider that if we subsequently doubt a doubt we had about our reasoning, that would suggest a restoration of some of the force of our original belief. We would then have instead of runaway skepticism an alternating sequence of pieces of skeptical reasoning that cancel each others’ effects on our justification in the original proposition, at least to some degree. We will argue that the outcome of the sequence of reflections Hume is imagining depends on information about a given case that is not known a priori. We conclude this from the fact that under three precise, explanatory, and viable contemporary reconstructions of what this kind of reasoning about reasoning could be like and how it has the potential to affect our original beliefs, a belief-extinguishing regress is not automatic or necessary. (shrink)

On analogy with testimony, I define a notion of a scientific theory’s lacking or having candor, in a testing situation, according to whether the theory under test is probabilistically relevant to the processes in the test procedures, and thereby to the reliability of test outcomes. I argue that this property identifies what is distinctive about those theories that Karl Popper denounced as exhibiting “reinforced dogmatism” through their self-protective behavior (e.g., psychoanalysis, Hegelianism, Marxism). I explore whether lack of candor interferes with (...) the testing of theories, and conclude that (1) our default attitude toward theories that lack candor in a given test should be suspicion, but (2) the circumstance that a theory lacks candor in a testing situation does not preclude obtaining independent evidence for the auxiliary assumptions to which the theory is probabilistically relevant, and thereby eliminating the problem that lack of candor creates. Thus, Popper was right to think that lack of candor is a bad thing, but wrong to conclude that candor is a criterion of the scientificity of a theory. Seeing this requires recognition of some differences between intuitive relevance and probabilistic relevance, and proper appreciation of the notion of screening off and of the fact that probabilistic relevance is not transitive. (shrink)

Epistemic injustice is injustice to a person qua knower. In one form of this phenomenon a speaker’s testimony is denied credence in a way that wrongs them. I argue that the received definition of this testimonial injustice relies too heavily on epistemic criteria that cannot explain why the moral concept of injustice should be invoked. I give an account of the nature of the wrong of epistemic injustice that has it depend not on the accuracy of judgments that are used (...) or made in the process of deciding whether to listen to or trust a speaker, but on whether the basis of the decision about a speaker is their reliability or their identity, and the account explains why the latter is a moral wrong. A key difference between the two accounts is how they classify the use of true statistical generalizations connecting identity and reliability. The received view implies that this cannot be an injustice, while the view proposed here implies that it can. As such the new view appears to imply a conflict between moral and epistemic obligations: it is morally wrong to use true statistical generalizations in certain contexts, yet they are part of our evidence, and we are epistemically obligated to take all of our evidence into account. I reconcile these two thoughts without adopting the currently popular view that a belief’s being morally wrong makes it epistemically unjustified, and I argue that following the principle of total evidence encourages epistemic justice rather than thwarting it. (shrink)

Health anxiety is, among other things, a response to a universal epistemological problem about whether changes in one’s body indicate serious illness, a problem that grows more challenging to the individual with age and with every advance in medical science, detection, and treatment. There is growing evidence that dysfunctional metacognitive beliefs – beliefs about thinking – are the driving factor, with dysfunctional substantive beliefs about the probability of illness a side‐effect, and that Metacognitive Therapy (MCT) is more effective than Cognitive (...) Behavioral Therapy (CBT). However, hypochondria is distinct from other forms of anxiety, I argue, in ways that make some reality‐checking techniques of CBT and MCT of limited usefulness. I propose a Re‐Calibration Technique (RCT) that complements these therapies by focusing on a metacognitive belief that has not been studied: the patient’s presumption of his own personal reliability in judging symptoms, an assumption exposed every time he disagrees with a doctor. I propose a technique whereby a patient keeps a long‐term register of every episode of alarm about symptoms and its resolution, possibly years later. When healthcare‐seeking impulses arise the patient then uses his own track record to re‐calibrate his confidence that medical attention is needed. The new technique allows one to improve self‐judgment about whether one has an illness or not by improving self‐knowledge of one’s own reliability. (shrink)

Why should we make our beliefs consistent or, more generally, probabilistically coherent? That it will prevent sure losses in betting and that it will maximize one’s chances of having accurate beliefs are popular answers. However, these justifications are self-centered, focused on the consequences of our coherence for ourselves. I argue that incoherence has consequences for others because it is liable to mislead others, to false beliefs about one’s beliefs and false expectations about one’s behavior. I argue that the moral obligation (...) of truthfulness thus constrains us to either conform to the logic our audience assumes we use, educate them in a new logic, or give notice that one will do neither. This does not show that probabilistic coherence is uniquely suited to making truthful communication possible, but I argue that classical probabilistic coherence is superior to other logics for maximizing efficiency in communication. (shrink)

This develops a framework for second-order conditionalization on statements about one's own epistemic reliability. It is the generalization of the framework of "Second-Guessing" (2009) to the case where the subject is uncertain about her reliability. See also "Epistemic Self-Doubt" (2017).

It is received wisdom that the skeptic has a devastating line of argument in the following. You probably think, he says, that you know that you have hands. But if you knew that you had hands, then you would also know that you were not a brain in a vat, a brain suspended in fluid with electrodes feeding you perfectly coordinated impressions that are generated by a supercomputer, of a world that looks and moves just like this one. You would (...) know you weren’t in this state if you knew you had hands, since having hands implies you are no brain in a vat. You obviously don’t know you’re not a brain in a vat, though—you have no evidence that would distinguish that state from the normal one you think you’re in. Therefore, by modus tollens, you don’t know you have hands. At least, the skeptic has a devastating argument, it is thought, if we grant him closure of knowledge under known implication, which many of us are inclined to do: roughly, if you know p, and you know that p implies q, then you know q. (shrink)

When we get evidence that tells us our belief-forming mechanisms may not be reliable this presents a thorny set of questions about whether and how to revise our original belief. This article analyzes aspects of the problem and a variety of approaches to its solution.

This paper argues that if knowledge is defined in terms of probabilistic tracking then the benefits of epistemic closure follow without the addition of a closure clause. (This updates my definition of knowledge in Tracking Truth 2005.) An important condition on this result is found in "Closure Failure and Scientific Inquiry" (2017).

Abstract: Knowledge requires more than mere true belief, and we also tend to think it is more valuable. I explain the added value that knowledge contributes if its extra ingredient beyond true belief is tracking . I show that the tracking conditions are the unique conditions on knowledge that achieve for those who fulfill them a strict Nash Equilibrium and an Evolutionarily Stable Strategy in what I call the True Belief Game. The added value of these properties, intuitively, includes preparedness (...) and an expectation of survival advantage. On this view knowledge is valuable not because knowledge persists but because it makes the bearer more likely to maintain an appropriate belief state—possibly nonbelief—through time and changing circumstances. When Socrates concluded that knowledge of the road to Larissa was no more valuable than true belief for the purpose of getting to Larissa, he did not take into account that one might want to be prepared for a possible meeting with a misleading sophist along the way, or for the possibility of road work. (shrink)

In the last three decades several cosmological principles and styles of reasoning termed 'anthropic' have been introduced into physics research and popular accounts of the universe and human beings' place in it. I discuss the circumstances of 'fine tuning' that have motivated this development, and what is common among the principles. I examine the two primary principles, and find a sharp difference between these 'Weak' and 'Strong' varieties: contrary to the view of the progenitors that all anthropic principles represent a (...) departure from Copernicanism in cosmology, the Weak Anthropic Principle is an instance of Copernicanism. It has close affinities with the step of Copernicus that Immanuel Kant took himself to be imitating in the 'critical' turn that gave rise to the Critique of Pure Reason. I conclude that the fact that a way of going about natural science mentions human beings is not sufficient reason to think that it is a subjective approach; in fact, it may need to mention human beings in order to be objective. (shrink)

This paper addresses two examples due to Peter Achinstein purporting to show that the positive relevance view of evidence is too strong, that is, that evidence need not raise the probability of what it is evidence for. The first example can work only if it makes a false assumption. The second example fails because what Achinstein claims is evidence is redundant with information we already have. Without these examples Achinstein is left without motivation for his account of evidence, which uses (...) the concept of explanation in addition to that of probability. (shrink)

Many who think that naked statistical evidence alone is inadequate for a trial verdict think that use of probability is the problem, and something other than probability – knowledge, full belief, causal relations – is the solution. I argue that the issue of whether naked statistical evidence is weak can be formulated within the probabilistic idiom, as the question whether likelihoods or only posterior probabilities should be taken into account in our judgment of a case. This question also identifies a (...) major difference between the Process Reliabilist and Probabilistic Tracking views of knowledge and other concepts. Though both are externalist, and probabilistic, epistemic theories, Tracking does and Process Reliabilism does not put conditions on likelihoods. So Tracking implies that a naked statistic is not adequate evidence about an individual, and does not yield knowledge, whereas the Reliabilist thinks it gives justified belief and knowledge. Not only does the Tracking view imply that naked statistical evidence is insufficient for a verdict, but it gives us resources to explain why, in terms of risk and the special conditions of a trial. (shrink)

Deduction is important to scientific inquiry because it can extend knowledge efficiently, bypassing the need to investigate everything directly. The existence of closure failure—where one knows the premises and that the premises imply the conclusion but nevertheless does not know the conclusion—is a problem because it threatens this usage. It means that we cannot trust deduction for gaining new knowledge unless we can identify such cases ahead of time so as to avoid them. For philosophically engineered examples we have “inner (...) alarm bells” to detect closure failure, but in scientific investigation we would want to use deduction for extension of our knowledge to matters we don’t already know that we couldn’t know. Through a quantitative treatment of how fast probabilistic sensitivity is lost over steps of deduction, I identify a condition that guarantees that the growth of potential error will be gradual; thus, dramatic closure failure is avoided. Whether the condition is fulfilled is often obvious, but sometimes it requires substantive investigation. I illustrate that not only safe deduction but the discovery of dramatic closure failures can lead to scientific advances. (shrink)

It is widely accepted that in fallible reasoning potential error necessarily increases with every additional step, whether inferences or premises, because it grows in the same way that the probability of a lengthening conjunction shrinks. As it stands, this is disappointing but, I will argue, not out of keeping with our experience. However, consulting an expert, proof-checking, constructing gap-free proofs, and gathering more evidence for a given conclusion also add more steps, and we think these actions have the potential to (...) improve our reliability or justifiedness. Thus, the received wisdom about the growth of error implies a skepticism about the possibility of improving our reliability and level of justification through effort. Paradoxically, and even more implausibly, taking steps to decrease your potential error necessarily increases it. I will argue that the self-help steps listed here are of a distinctive type, involving composition rather than conjunction. Error grows differently over composition than over conjunction, I argue, and this dissolves the apparent paradox. (shrink)

The transferability problem—whether the results of an experiment will transfer to a treatment population—affects not only Randomized Controlled Trials but any type of study. The problem for any given type of study can also, potentially, be addressed to some degree through many different types of study. The transferability problem for a given RCT can be investigated further through another RCT, but the variables to use in the further experiment must be discovered. This suggests we could do better on the epistemological (...) problem of transferability by promoting, in the repeated process of formulating public health guidelines, feedback loops of information from the implementation setting back to researchers who are defining new studies. (shrink)

One of the most common criticisms one hears of the idea of granting a legitimate role for social values in theory choice in science is that it just doesn’t make sense to regard social preferences as relevant to the truth or to the way things are. “What is at issue,” wrote Susan Haack, is “whether it is possible to derive an ‘is’ from an ‘ought.’ ” One can see that this is not possible, she concludes, “as soon as one expresses (...) it plainly: that propositions about what states of affairs are desirable or deplorable could be evidence that things are, or are not, so” (Haack 1993a, 35, emphasis in original). The purpose of this chapter is not to determine whether this widespread view is correct, but rather to show that even if we grant it (which I do), we may still consistently believe that social values have a legitimate role in theory choice in science. I will defend this conclusion by outlining a view about social values and theory choice that is available to a Constructive Empiricist anti-realist, but not to a realist. (shrink)

Over the centuries since the modern scientific revolution that started with Copernicus, Galileo, Kepler, and Newton, two things have changed that have required reorientation of our assumptions and re-education of our reflexes. First, we have learned that even the very best science is fallible; eminently successful theories investigated and supported through the best methods, and by the best evidence available, might be not just incomplete but wrong. That is, it is possible to have a justified belief that is false.

Disclaimer: This work on marginal science has not been funded by the National Science Foundation.

This is a very short textbook on probabilistic reasoning, expected utility decision-making, cognitive biases, and self-correction, especially in application to medical examples. It also includes a chapter on concepts of health.

Capital punishment—the legally authorized killing of a criminal offender by an agent of the state for the commission of a crime—stands in special need of moral justification. This is because execution is a particularly severe punishment. Execution is different in kind from monetary and custodial penalties in an obvious way: execution causes the death of an offender. While fines and incarceration set back some of one’s interests, death eliminates the possibility of setting and pursuing ends. While fines and incarceration narrow (...) one’s routes to happiness, death eliminates its possibility. Not surprisingly, there is much debate about the moral permissibility of capital punishment. This entry maps the terrain of this debate. The first section discusses justifications of the death penalty as they appear in major theories of punishment. The second section surveys moral objections to execution that apply to most justifications. The third addresses procedural criticisms, which do not target the morality of execution so much as the justice of its implementation. (shrink)

Critics of the computational connectionism of the last decade suggest that it shares undesirable features with earlier empiricist or associationist approaches, and with behaviourist theories of learning. To assess the accuracy of this charge the works of earlier writers are examined for the presence of such features, and brief accounts of those found are given for Herbert Spencer, William James and the learning theorists Thorndike, Pavlov and Hull. The idea that cognition depends on associative connections among large networks of neurons (...) is indeed one with precedents, although the implications of this for psychological issues have been interpreted variously — not all versions of connectionism are alike. (shrink)

By transcendental aesthetic, Kant means “the science of all principles of a priori sensibility” (A 21/B 35). These, he argues, are the laws that properly direct our judgments of taste (B 35 – 36 fn.), i.e. our aesthetic judgments as we ordinarily understand that notion in the context of contemporary art. Thus the first part of the Critique of Pure Reason, entitled the Transcendental Aesthetic, enumerates the necessary presuppositions of, among other things, our ability to make empirical judgments about particular (...) works of art. These presuppositions are sensible rather than intellectual because on Kant's view, all intellection that considers objects of any kind, whether abstract or concrete, must at base connect to actual, material objects with which we come into direct contact; and this we can do only through sensibility (A 19/B 33). Thus the following discussion explores what Kant claims must be true of us in order to make the sorts of aesthetic judgments we make, rather than any particular class or quality of aesthetic judgments itself. On Kant's view, what must be true of us in order to make aesthetic judgments is not different from what must be true of us in order to make any other kind of judgment about empirical objects. This last point is worth emphasizing, in order to correct an interpretation of Kant's account of aesthetic judgment in the Critique of Judgment that wrongly reads Kant as claiming that aesthetic judgments do not have to satisfy the same basic requirements of judgment that any other kind of judgment also must satisfy, such as the synthetic subsumption of such objects under certain necessary and hard-wired concepts of understanding, the internal coherence of such judgments with other, non-aesthetic ones of a more abstract and comprehensive character, the unified consciousness within which such judgments are intelligibly made, and the like. Of course Kant recognizes the special character of aesthetic judgments and unpacks it in the... (shrink)

Urban infrastructures serve as the backbone of modern economies, mediating global exchanges and responding to urban demands. Yet, our comprehension of these complex structures, particularly within diverse socio-political terrain, remains fragmented. In bridging this knowledge gap, this study delves into “boundary objects”—entities enabling diverse stakeholders to collaborate without a comprehensive consensus. Central to our investigation is the hypothesis that oceanic infrastructural developments are instrumental in molding the interface of urban, industrial, and energy sectors within marine contexts. Our lens is directed (...) at the Gulf of Mexico, which is distinguished by its industrial depth and expansive marine grid. We highlight the Gulf Intracoastal Waterway’s (GIWW) paramount role in regional movement and the ecological facets of practices such as dredging, which is vital for transport and coastal conservation. A striking revelation of our study is the transformation of offshore structures in the Gulf into vibrant marine habitats. Emphasizing the intertwined nature of marine infrastructures, we denote oceans as pivotal platforms for impending urban expansion, especially as land resources wane. Our research aspires to validate the role played by oceans as a nexus in the urban–industrial–energy fusion. (shrink)

Whataboutism is een strategie waarbij op een beschuldiging wordt gereageerd met een wedervraag die eveneens een beschuldiging impliceert, waardoor de oorspronkelijke vraag eerder wordt ontweken dan beantwoord. Het is een effectieve methode om de aandacht te verplaatsen naar een andere situatie door een vergelijkbaar, dan wel onvergelijkbaar, contrast te bieden, waardoor de beschuldigde het eigen gedrag probeert te rechtvaardigen en verantwoordelijkheid probeert te ontlopen. Maar niet alle vormen van whataboutism impliceren echter een drogredenering, noch worden ze altijd verkeerd toegepast. Het (...) contrast dat voortkomt uit de vraag ‘what about’ kan dan een cruciale bijdrage leveren aan een situatie die een verdere kritische analyse vereist, en daarmee de geloofwaardigheid van de argumentatie versterken. (shrink)

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

In recent years, there has been a heated debate about how to interpret findings that seem to show that humans rapidly and automatically calculate the visual perspectives of others. In the current study, we investigated the question of whether automatic interference effects found in the dot-perspective task (Samson, Apperly, Braithwaite, Andrews, & Bodley Scott, 2010) are the product of domain-specific perspective-taking processes or of domain-general “submentalizing” processes (Heyes, 2014). Previous attempts to address this question have done so by implementing inanimate (...) controls, such as arrows, as stimuli. The rationale for this is that submentalizing processes that respond to directionality should be engaged by such stimuli, whereas domain-specific perspective-taking mechanisms, if they exist, should not. These previous attempts have been limited, however, by the implied intentionality of the stimuli they have used (e.g. arrows), which may have invited participants to imbue them with perspectival agency. Drawing inspiration from “novel entity” paradigms from infant gaze-following research, we designed a version of the dot-perspective task that allowed us to precisely control whether a central stimulus was viewed as animate or inanimate. Across four experiments, we found no evidence that automatic “perspective-taking” effects in the dot-perspective task are modulated by beliefs about the animacy of the central stimulus. Our results also suggest that these effects may be due to the task-switching elements of the dot-perspective paradigm, rather than automatic directional orienting. Together, these results indicate that neither the perspective-taking nor the standard submentalizing interpretations of the dot-perspective task are fully correct. (shrink)

This study aimed to identify the learning and business incubation processes and their impact on developing the performance of business incubators in Gaza Strip, and the study relied on the descriptive analytical approach, and the study population consisted of all employees working in business incubators in Gaza Strip in addition to experts and consultants in incubators where their total number reached (62) individuals, and the researchers used the questionnaire as a main tool to collect data through the comprehensive survey method, (...) where (55) questionnaires were retrieved with a recovery rate of (88.7%). The results of the study showed that there is a high approval of the variables of the study, where the dimension of incubation operations came with a relative weight (84.89%), followed by the learning dimension which got a relative weight (82.50%), while the performance level of the incubators got a relative weight (80.12%) and as the study results showed There is a positive relationship statistically between the two dimensions of learning and business incubation processes and performance development in business incubators, and the linear regression analysis model showed that the main effect in improving the performance of business incubators is "after business incubation operations" while it showed weak effect after learning. The study came out with several recommendations, the most important of which is that business incubators seek to reinforce the learning process and incubation processes for business, and the need to periodically evaluate their performance, and that a more effective mechanism be designed to follow up with companies after the end of the incubation period and monitor the progress of these companies. (shrink)

This paper explores how the diagnosis of mental disorder may affect the diagnosed subject’s self-concept by supplying an account that emphasizes the influence of autobiographical and social narratives on self-understanding. It focuses primarily on the diagnoses made according to the criteria provided by the Diagnostic Statistical Manual of Mental Disorders (DSM), and suggests that the DSM diagnosis may function as a source of narrative that affects the subject’s self-concept. Engaging in this analysis by appealing to autobiographies and memoirs written by (...) people diagnosed with mental disorder, the paper concludes that a DSM diagnosis is a double-edged sword for self- concept. On the one hand, it sets the subject’s experience in an established classificatory system which can facilitate self-understanding by providing insight into subject’s condition and guiding her personal growth, as well as treatment and recovery. In this sense, the DSM diagnosis may have positive repercussions on self-development. On the other hand, however, given the DSM’s symptom-based approach and its adoption of the Biomedical Disease model, a diagnosis may force the subject to make sense of her condition divorced from other elements in her life that may be affecting her mental- health. It may lead her frame her experience only as an irreversible imbalance. This form of self-understanding may set limits on the subject’s hopes of recovery and may create impediments to her flourishing. (shrink)

Since the launch of applications such as DALL-E, Midjourney, and Stable Diffusion, generative artificial intelligence has been controversial as a tool for creating artwork. While some have presented longtermist worries about these technologies as harbingers of fully automated futures to come, more pressing is the impact of generative AI on creative labour in the present. Already, business leaders have begun replacing human artistic labour with AI-generated images. In response, the artistic community has launched a protest movement, which argues that AI (...) image generation is a kind of theft. This paper analyzes, substantiates, and critiques these arguments, concluding that AI image generators involve an unethical kind of labour theft. If correct, many other AI applications also rely upon theft. (shrink)

Abstract— Anatomy of the anterior compartment includes the tibia and the fibula. It also includes the tibialis anterior tendon, the extensor hallucis longus tendon and the extensor digitorum longus tendons. The anterior tibial artery and the deep peroneal nerve and finally the superior and inferior extensor retinaculum. In this paper an expert system was designed to help users to correctly diagnose ankle problems. There are many structures present at the anterior aspect of the ankle; these structures are often susceptible to (...) injury common injuries and conditions around the anterior ankle. Clips expert system language was used to design and implement this expert system. (shrink)

It is becoming increasingly common for authoritarian regimes to leverage digital technologies to surveil, repress and manipulate their citizens. Experts typically refer to this practice as digital authoritarianism (DA). Existing definitions of DA consistently presuppose a politically repressive agent intentionally exploiting digital technologies to pursue authoritarian ends. I refer to this as the intention-based definition. This paper argues that this definition is untenable as a general description of DA. I begin by illustrating the current predominance of the intention-based definition (Section (...) 2). Section 3 then presents four counterexamples to this definition: benign surveillance; digital sovereignty; attention-harvesting algorithms; and tech-induced loneliness. In each case, we witness authoritarianism being promoted by digital technologies without any evidence of this being intentionally caused by politically repressive agents. Based on these observations, I contend that the intention-based definition is underinclusive and is therefore unsustainable. Section 4 outlines an improved definition of DA – what I call the promotion-based definition. Since this more expansive definition does not posit intentional, politically repressive agency as a precondition of DA, it can accommodate the counterexamples discussed in Section 3. Moreover, it enables us to catch a broader spectrum of cases of DA, such as tech-induced loneliness, which those adhering to the intention-based definition are prone to overlook. After outlining further practical benefits of the promotion-based definition, I argue that we still need to distinguish between intentional and unintentional forms of DA since they call for distinct types of remedial action. -/- . (shrink)

Many scholars, including G. A. Cohen, Daniel Attas, and George Brenkert, have denied that a Kantian defense of self-ownership is possible. Kant's ostensible hostility to self-ownership can be resolved, however, upon reexamination of the Groundwork and the Metaphysics of Morals. Moreover, two novel Kantian defenses of self-ownership (narrowly construed) can be devised. The first shows that maxims of exploitation and paternalism that violate self-ownership cannot be universalized, as this leads to contradictions in conception. The second shows that physical coercion against (...) rational agents involves a profound status wrong--namely, their treatment as children or animals--and that this system of differential status and treatment (including self-ownership rights for rational agents) can be morally justified by our capacity for autonomy. (shrink)

As these opening quotes acknowledge, the Prisoner’s Dilemma (PD) represents a core puzzle within the formal mathematics of game theory.3 Its rise in conspicuity is evident figure 2.1 above demonstrating a relatively steady rise in incidences of the phrase’s usage between 1960 to 1995, with a stable presence persisting into the twenty first century. This famous two-person “game,” with a stock narrative cast in terms of two prisoners who each independently must choose whether to remain silent or speak, each advancing (...) self-interest at the expense of the other and thereby achieving a mutually suboptimal outcome, mires any social interaction it is applied to into perplexity. The logic of this game proves the inverse of Adam Smith’s invisible hand: individuals acting on self interest will achieve a mutually suboptimal outcome. However, as this chapter illuminates, the assumptions underlying game theory drive this conclusion. (shrink)

Is capitalism inherently predatory? Must there be winners and losers? Is public interest outdated and free-riding rational? Is consumer choice the same as self-determination? Must bargainers abandon the no-harm principle? Prisoners of Reason recalls that classical liberal capitalism exalted the no-harm principle. Although imperfect and exclusionary, modern liberalism recognized individual human dignity alongside individuals' responsibility to respect others. Neoliberalism, by contrast, views life as ceaseless struggle. Agents vie for scarce resources in antagonistic competition in which every individual seeks dominance. This (...) political theory is codified in non-cooperative game theory; the neoliberal citizen and consumer is the strategic rational actor. Rational choice justifies ends irrespective of means. Money becomes the medium of all value. Solidarity and good will are invalidated. Relationships are conducted on a quid pro quo basis. However, agents can freely opt out of this cynical race to the bottom by embracing a more expansive range of coherent action. (shrink)

Abstract. Intelligent Tutoring System Builder (ITSB) is an authoring tool designed and developed to aid teachers in constructing intelligent tutoring systems in a multidisciplinary fields. The teacher is needed to create a set of pedagogical fundamentals, which, in line, are inured to automatically build up a broad tutor framework and construct an intelligent tutoring system. In this paper an explanation of the theory and the architecture of the tool is outlined. A presentation of several system components, the requirements of the (...) different components, integration of these components in ITSB tool are shown. Furthermore, implanting of requirements, cognitive principle, and common design fundamentals in the tool to ease the use of teachers. A variety of design matters, an example of building an intelligent tutoring system for teaching Java language using ITSB tool and an evaluation are presented. (shrink)

We propose a formal framework for interpretable machine learning. Combining elements from statistical learning, causal interventionism, and decision theory, we design an idealised explanation game in which players collaborate to find the best explanation for a given algorithmic prediction. Through an iterative procedure of questions and answers, the players establish a three-dimensional Pareto frontier that describes the optimal trade-offs between explanatory accuracy, simplicity, and relevance. Multiple rounds are played at different levels of abstraction, allowing the players to explore overlapping causal (...) patterns of variable granularity and scope. We characterise the conditions under which such a game is almost surely guaranteed to converge on a optimal explanation surface in polynomial time, and highlight obstacles that will tend to prevent the players from advancing beyond certain explanatory thresholds. The game serves a descriptive and a normative function, establishing a conceptual space in which to analyse and compare existing proposals, as well as design new and improved solutions. (shrink)

This paper explores how the Leviathan that projects power through nuclear arms exercises a unique nuclearized sovereignty. In the case of nuclear superpowers, this sovereignty extends to wielding the power to destroy human civilization as we know it across the globe. Nuclearized sovereignty depends on a hybrid form of power encompassing human decision-makers in a hierarchical chain of command, and all of the technical and computerized functions necessary to maintain command and control at every moment of the sovereign's existence: this (...) sovereign power cannot sleep. This article analyzes how the form of rationality that informs this hybrid exercise of power historically developed to be computable. By definition, computable rationality must be able to function without any intelligible grasp of the context or the comprehensive significance of decision-making outcomes. Thus, maintaining nuclearized sovereignty necessarily must be able to execute momentous life and death decisions without the type of sentience we usually associate with ethical individual and collective decisions. (shrink)