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  1. Run the Experiment, Publish the Study, Close the Sale: Commercialized Biomedical Research.Aleta Quinn - 2016 - De Ethica 2 (3):5-21.
    Business models for biomedical research prescribe decentralization due to market selection pressures. I argue that decentralized biomedical research does not match four normative philosophical models of the role of values in science. Non-epistemic values affect the internal stages of for-profit biomedical science. Publication planning, effected by Contract Research Organizations, inhibits mechanisms for transformative criticism. The structure of contracted research precludes attribution of responsibility for foreseeable harm resulting from methodological choices. The effectiveness of business strategies leads to overrepresentation of profit values (...)
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  2. Should Phenomenological Approaches to Illness Be Wary of Naturalism?Juliette Ferry-Danini - 2019 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 73:10-18.
    In some quarters within philosophy of medicine, more particularly in the phenomenological approaches, naturalism is looked upon with suspicion. This paper argues, first, that it is necessary to distinguish between two expressions of this attitude towards naturalism: phenomenological approaches to illness disagree with naturalism regarding various theoretical claims and they disapprove of naturalism on an ethical level. Second, this paper argues that both the disagreement with and the disapproval of naturalism are to a large extent confused. It then offers some (...)
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  3. Healthcare Practice, Epistemic Injustice, and Naturalism.Ian James Kidd & Havi Carel - 2018 - Royal Institute of Philosophy Supplement 84:1-23.
    Ill persons suffer from a variety of epistemically-inflected harms and wrongs. Many of these are interpretable as specific forms of what we dub pathocentric epistemic injustices, these being ones that target and track ill persons. We sketch the general forms of pathocentric testimonial and hermeneutical injustice, each of which are pervasive within the experiences of ill persons during their encounters in healthcare contexts and the social world. What’s epistemically unjust might not be only agents, communities and institutions, but the theoretical (...)
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  4. Assigning Functions to Medical Technologies.Alexander Mebius - 2017 - Philosophy and Technology 30 (3):321-338.
    Modern health care relies extensively on the use of technologies for assessing and treating patients, so it is important to be certain that health care technologies perform their professed functions in an effective and safe manner. Philosophers of technology have developed methods to assign and evaluate the functions of technological products, the major elements of which are described in the ICE theory. This paper questions whether the standard of evidence advocated by the ICE theory is adequate for ascribing and assessing (...)
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  5. How Evidence-Based Medicine is Failing Due to Biased Trials and Selective Publication.Susanna Every-Palmer & Jeremy Howick - 2014 - Journal of Evaluation in Clinical Practice 20 (6):908-914.
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  6. Philosophical Controversies in the Evaluation of Medical Treatments : With a Focus on the Evidential Roles of Randomization and Mechanisms in Evidence-Based Medicine.Alexander Mebius - 2015 - Dissertation, KTH Royal Institute of Technology
    This thesis examines philosophical controversies surrounding the evaluation of medical treatments, with a focus on the evidential roles of randomised trials and mechanisms in Evidence-Based Medicine. Current 'best practice' usually involves excluding non-randomised trial evidence from systematic reviews in cases where randomised trials are available for inclusion in the reviews. The first paper challenges this practice and evaluates whether adding of evidence from non-randomised trials might improve the quality and precision of some systematic reviews. The second paper compares the alleged (...)
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  7. Medicine is Not Science.Clifford Miller & Donald W. Miller - 2014 - European Journal for Person Centered Healthcare 2 (2):144-153.
    ABSTRACT: Abstract Most modern knowledge is not science. The physical sciences have successfully validated theories to infer they can be used universally to predict in previously unexperienced circumstances. According to the conventional conception of science such inferences are falsified by a single irregular outcome. And verification is by the scientific method which requires strict regularity of outcome and establishes cause and effect. -/- Medicine, medical research and many “soft” sciences are concerned with individual people in complex heterogeneous populations. These populations (...)
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  8. The Path to Public Office: Medicine Versus Law.Michael L. Riordan - 1985 - Perspectives in Biology and Medicine 29 (2):316-325.
    Essay by Dr. Michael L. Riordan, the founder of Gilead Sciences, on the comparative utility of a medical versus legal education as preparation for public office.
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  9. Defining Neglected Disease.Alex Broadbent - 2011 - Biosocieties 6 (1):51-70.
    In this article I seek to say what it is for something to count as a neglected disease. I argue that neglect should be defined in terms of efforts at prevention, mitigation and cure, and not solely in terms of research dollars per disability-adjusted life-year. I further argue that the trend towards multifactorialism and risk factor thinking in modern epidemiology has lent credibility to the erroneous view that the primary problem with neglected diseases is a lack of research. A more (...)
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  10. Risk and Disease.Peter H. Schwartz - 2008 - Perspectives in Biology and Medicine 51 (3):320-334.
    The way that diseases such as high blood pressure (hypertension), high cholesterol, and diabetes are defined is closely tied to ideas about modifiable risk. In particular, the threshold for diagnosing each of these conditions is set at the level where future risk of disease can be reduced by lowering the relevant parameter (of blood pressure, low-density lipoprotein, or blood glucose, respectively). In this article, I make the case that these criteria, and those for diagnosing and treating other “risk-based diseases,” reflect (...)
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  11. Genetic Determinism and the Innate-Acquired Distinction.Maria Kronfeldner - 2009 - Medicine Studies 1 (2):167-181.
    This article illustrates in which sense genetic determinism is still part of the contemporary interactionist consensus in medicine. Three dimensions of this consensus are discussed: kinds of causes, a continuum of traits ranging from monogenetic diseases to car accidents, and different kinds of determination due to different norms of reaction. On this basis, this article explicates in which sense the interactionist consensus presupposes the innate?acquired distinction. After a descriptive Part 1, Part 2 reviews why the innate?acquired distinction is under attack (...)
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Philosophy of Medicine, Miscellaneous
  1. Heat in Renaissance Philosophy.Filip Buyse - 2020 - In Marco Sgarbi (ed.), Encyclopedia of Renaissance Philosophy. Berlin: Springer.
    The term ‘heat’ originates from the Old English word hǣtu, a word of Germanic origin; related to the Dutch ‘hitte’ and German ‘Hitze’. Today, we distinguish three different meanings of the word ‘heat’. First, ‘heat’ is understood in colloquial English as ‘hotness’. There are, in addition, two scientific meanings of ‘heat’. ‘Heat’ can have the meaning of the portion of energy that changes with a change of temperature. And finally, ‘heat’ can have the meaning of the transfer of thermal energy (...)
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  2. Modeling the Invention of a New Inference Rule: The Case of ‘Randomized Clinical Trial’ as an Argument Scheme for Medical Science.Jodi Schneider & Sally Jackson - 2018 - Argument and Computation 9 (2):77-89.
    A background assumption of this paper is that the repertoire of inference schemes available to humanity is not fixed, but subject to change as new schemes are invented or refined and as old ones are obsolesced or abandoned. This is particularly visible in areas like health and environmental sciences, where enormous societal investment has been made in finding ways to reach more dependable conclusions. Computational modeling of argumentation, at least for the discourse in expert fields, will require the possibility of (...)
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  3. Renewing Medicine’s Basic Concepts: On Ambiguity.Joel Michael Reynolds - 2018 - Philosophy, Ethics, and Humanities in Medicine 13 (1):8.
    I argue that the concept of normality in medical research and practice is inextricable from that of ambiguity. I do so in the context of Edmund Pellegrino's call for a renewed reflection on medicine’s basic concepts and by drawing on work in critical disability studies concerning Deafness and body integrity identity disorder. If medical practitioners and philosophers of medicine wish to improve their understanding of the meaning of medicine as well as its concrete practice, they should take seriously the import (...)
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  4. Evolution, Dysfunction, and Disease: A Reappraisal.Paul E. Griffiths & John Matthewson - 2016 - British Journal for the Philosophy of Science 69 (2):301-327.
    Some ‘naturalist’ accounts of disease employ a biostatistical account of dysfunction, whilst others use a ‘selected effect’ account. Several recent authors have argued that the biostatistical account offers the best hope for a naturalist account of disease. We show that the selected effect account survives the criticisms levelled by these authors relatively unscathed, and has significant advantages over the BST. Moreover, unlike the BST, it has a strong theoretical rationale and can provide substantive reasons to decide difficult cases. This is (...)
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  5. Universal Etiology, Multifactorial Diseases and the Constitutive Model of Disease Classification.Jonathan Fuller - 2018 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 67:8-15.
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  6. Representing Disease Courses: An Application of the Neurological Disease Ontology to Multiple Sclerosis Typology.Mark Jensen, Alexander P. Cox, Barry Smith & Alexander Diehl - 2013 - In Proceedings of the Fourth International Conference on Biomedical Ontology (ICBO), CEUR, vol. 1060.
    The Neurological Disease Ontology (ND) is being developed to provide a comprehensive framework for the representation of neurological diseases (Diehl et al., 2013). ND utilizes the model established by the Ontology for General Medical Science (OGMS) for the representation of entities in medicine and disease (Scheuermann et al., 2009). The goal of ND is to include information for each disease concerning its molecular, genetic, and environmental origins, the processes involved in its etiology and realization, as well as its clinical presentation (...)
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  7. Immune System, Immune Self. Introduction.Bartłomiej Świątczak - 2012 - Avant: Trends in Interdisciplinary Studies 3 (1):12-18.
    The idea that the immune system distinguishes between self and non-self was one of the central assumptions of immunology in the second half of 20 th century. This idea influenced experimental design and data interpretation. However, in the face of new evidence there is a need for a new conceptual framework in immunology.
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  8. Hollow Hunt for Harms.Jacob Stegenga - 2016 - Perspectives on Science 24 (5):481-504.
    Harms of medical interventions are systematically underestimated in clinical research. Numerous factors—conceptual, methodological, and social—contribute to this underestimation. I articulate the depth of such underestimation by describing these factors at the various stages of clinical research. Before any evidence is gathered, the ways harms are operationalized in clinical research contributes to their underestimation. Medical interventions are first tested in phase 1 ‘first in human’ trials, but evidence from these trials is rarely published, despite the fact that such trials provide the (...)
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  9. “Was Canguilhem a Biochauvinist? Goldstein, Canguilhem and the Project of ‘Biophilosophy’".Charles Wolfe - 2015 - In Darian Meacham (ed.), Medicine and Society, New Continental Perspectives (Dordrecht: Springer, Philosophy and Medicine Series, 2015). Springer. pp. 197-212.
    Canguilhem is known to have regretted, with some pathos, that Life no longer serves as an orienting question in our scientific activity. He also frequently insisted on a kind of uniqueness of organisms and/or living bodies – their inherent normativity, their value-production and overall their inherent difference from mere machines. In addition, Canguilhem acknowledged a major debt to the German neurologist-theoretician Kurt Goldstein, author most famously of The Structure of the Organism in 1934; along with Merleau-Ponty, Canguilhem was the main (...)
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  10. New Directions in Philosophy of Medicine.Jacob Stegenga, Ashley Kennedy, Serife Tekin, Saana Jukola & Robyn Bluhm - forthcoming - In James Marcum (ed.), Bloomsbury Companion to Contemporary Philosophy of Medicine. Bloomsbury Academic. pp. 343-367.
    The purpose of this chapter is to describe what we see as several important new directions for philosophy of medicine. This recent work (i) takes existing discussions in important and promising new directions, (ii) identifies areas that have not received sufficient and deserved attention to date, and/or (iii) brings together philosophy of medicine with other areas of philosophy (including bioethics, philosophy of psychiatry, and social epistemology). To this end, the next part focuses on what we call the “epistemological turn” in (...)
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  11. Hippocrates' Complaint.Guido del Giudice - 2015 - la Biblioteca di Via Senato (9):04-09.
    The fascinating Journey of the Renaissance Medicine.
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  12. Il melanconico lamento di Ippocrate.Guido del Giudice - 2015 - la Biblioteca di Via Senato (9):04-09.
    Un viaggio nell'arte medica del Rinascimento.
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  13. Translating Trial Results in Clinical Practice: The Risk GP Model.Jonathan Fuller & Luis J. Flores - 2016 - Journal of Cardiovascular Translational Research 9:167-168.
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  14. Ontologies, Disorders and Prototypes.Cristina Amoretti, Marcello Frixione, Antonio Lieto & Greta Adamo - 2016 - In Proceedings of IACAP 2016.
    As it emerged from philosophical analyses and cognitive research, most concepts exhibit typicality effects, and resist to the efforts of defining them in terms of necessary and sufficient conditions. This holds also in the case of many medical concepts. This is a problem for the design of computer science ontologies, since knowledge representation formalisms commonly adopted in this field (such as, in the first place, the Web Ontology Language - OWL) do not allow for the representation of concepts in terms (...)
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  15. Opening the Black Box of Commodification: A Philosophical Critique of Actor-Network Theory as Critique.Henrik Rude Hvid - manuscript
    This article argues that actor-network theory, as an alternative to critical theory, has lost its critical impetus when examining commodification in healthcare. The paper claims that the reason for this, is the way in which actor-network theory’s anti-essentialist ontology seems to black box 'intentionality' and ethics of human agency as contingent interests. The purpose of this paper was to open the normative black box of commodification, and compare how Marxism, Habermas and ANT can deal with commodification and ethics in healthcare. (...)
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  16. Models of Mental Illness.Jacqueline Anne Sullivan - 2016 - In Harold Kincaid, Jeremy Simon & Miriam Solomon (eds.), The Routledge Companion to the Philosophy of Medicine. Routledge. pp. 455-464.
    This chapter has two aims. The first aim is to compare and contrast three different conceptual-explanatory models for thinking about mental illness with an eye towards identifying the assumptions upon which each model is based, and exploring the model’s advantages and limitations in clinical contexts. Major Depressive Disorder is used as an example to illustrate these points. The second aim is to address the question of what conceptual-theoretical framework for thinking about mental illness is most likely to facilitate the discovery (...)
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  17. Effectiveness of Medical Interventions.Jacob Stegenga - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 54:34-44.
    To be effective, a medical intervention must improve one's health by targeting a disease. The concept of disease, though, is controversial. Among the leading accounts of disease-naturalism, normativism, hybridism, and eliminativism-I defend a version of hybridism. A hybrid account of disease holds that for a state to be a disease that state must both (i) have a constitutive causal basis and (ii) cause harm. The dual requirement of hybridism entails that a medical intervention, to be deemed effective, must target either (...)
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  18. Measuring Effectiveness.Jacob Stegenga - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 54:62-71.
    Measuring the effectiveness of medical interventions faces three epistemological challenges: the choice of good measuring instruments, the use of appropriate analytic measures, and the use of a reliable method of extrapolating measures from an experimental context to a more general context. In practice each of these challenges contributes to overestimating the effectiveness of medical interventions. These challenges suggest the need for corrective normative principles. The instruments employed in clinical research should measure patient-relevant and disease-specific parameters, and should not be sensitive (...)
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  19. Prediction in Epidemiology and Medicine.Jonathan Fuller, Alex Broadbent & Luis J. Flores - 2015 - Studies in History and Philosophy of Science Part C.
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  20. The Risk GP Model: The Standard Model of Prediction in Medicine.Jonathan Fuller & Luis J. Flores - 2015 - Studies in History and Philosophy of Science Part C 54:49-61.
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  21. Judging Quality and Coordination in Biomarker Diagnostic Development.Spencer Phillips Hey - 2015 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 30 (2):207-227.
    What makes a high-quality biomarker experiment? The success of personalized medicine hinges on the answer to this question. In this paper, I argue that judgment about the quality of biomarker experiments is mediated by the problem of theoretical underdetermination. That is, the network of biological and pathophysiological theories motivating a biomarker experiment is sufficiently complicated that it often frustrates valid interpretation of the experimental results. Drawing on a case-study in biomarker diagnostic development from neurooncology, I argue that this problem of (...)
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  22. Diseases, Patients and the Epistemology of Practice: Mapping the Borders of Health, Medicine and Care.Michael Loughlin, Robyn Bluhm, Jonathan Fuller, Stephen Buetow, Benjamin R. Lewis & Brent M. Kious - 2015 - Journal of Evaluation in Clinical Practice 21 (3):357-364.
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  23. Philosophy, Medicine and Health Care – Where We Have Come From and Where We Are Going.Michael Loughlin, Robyn Bluhm, Jonathan Fuller, Stephen Buetow, Ross E. G. Upshur, Kirstin Borgerson, Maya J. Goldenberg & Elselijn Kingma - 2014 - Journal of Evaluation in Clinical Practice 20 (6):902-907.
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  24. Book Review. Philosophy of Epidemiology by A. Broadbent. [REVIEW]Jonathan Fuller - 2014 - Journal of Evaluation in Clinical Practice 20 (6):1002-1004.
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  25. Down with the Hierarchies.Jacob Stegenga - 2014 - Topoi 33 (2):313-322.
    Evidence hierarchies are widely used to assess evidence in systematic reviews of medical studies. I give several arguments against the use of evidence hierarchies. The problems with evidence hierarchies are numerous, and include methodological shortcomings, philosophical problems, and formal constraints. I argue that medical science should not employ evidence hierarchies, including even the latest and most-sophisticated of such hierarchies.
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  26. Diversity in Epistemic Communities: A Response to Clough.Maya J. Goldenberg - 2014 - Social Epistemology Review and Reply Collective Vol. 3, No. 5.
    In Clough’s reply paper to me (http://wp.me/p1Bfg0-1aN), she laments how feminist calls for diversity within scientific communities are inadvertently sidelined by our shared feminist empiricist prescriptions. She offers a novel justification for diversity within epistemic communities and challenges me to accept this addendum to my prior prescriptions for biomedical research communities (Goldenberg 2013) on the grounds that they are consistent with the epistemic commitments that I already endorse. In this response, I evaluate and accept her challenge.
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  27. How Can Feminist Theories of Evidence Assist Clinical Reasoning and Decision-Making?Maya J. Goldenberg - 2013 - Social Epistemology (TBA):1-28.
    While most of healthcare research and practice fully endorses evidence-based healthcare, a minority view borrows popular themes from philosophy of science like underdetermination and value-ladenness to question the legitimacy of the evidence-based movement’s philosophical underpinnings. While the feminist origins go unacknowledged, those critics adopt a feminist reading of the “gap argument” to challenge the perceived objectivism of evidence-based practice. From there, the critics seem to despair over the “subjective elements” that values introduce to clinical reasoning, demonstrating that they do not (...)
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  28. Unifying Diseases From a Genetic Point of View: The Example of the Genetic Theory of Infectious Diseases.Marie Darrason - 2013 - Theoretical Medicine and Bioethics 34 (4):327-344.
    In the contemporary biomedical literature, every disease is considered genetic. This extension of the concept of genetic disease is usually interpreted either in a trivial or genocentrist sense, but it is never taken seriously as the expression of a genetic theory of disease. However, a group of French researchers defend the idea of a genetic theory of infectious diseases. By identifying four common genetic mechanisms (Mendelian predisposition to multiple infections, Mendelian predisposition to one infection, and major gene and polygenic predispositions), (...)
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  29. Towards Industrial Strength Philosophy: How Analytical Ontology Can Help Medical Informatics.Barry Smith & Werner Ceusters - 2003 - Interdisciplinary Science Reviews 28 (2):106–111.
    Initially the problems of data integration, for example in the field of medicine, were resolved in case by case fashion. Pairs of databases were cross-calibrated by hand, rather as if one were translating from French into Hebrew. As the numbers and complexity of database systems increased, the idea arose of streamlining these efforts by constructing one single benchmark taxonomy, as it were a central switchboard, into which all of the various classification systems would need to be translated only once. By (...)
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  30. Dispositions and the Infectious Disease Ontology.Albert Goldfain, Barry Smith & Lindsay Cowell - 2010 - In Formal Ontology in Information Systems: Proceedings of the Sixth International Conference (FOIS). IOS Press. pp. 400-413.
    This paper addresses the use of dispositions in the Infectious Disease Ontology (IDO). IDO is an ontology constructed according to the principles of the Open Biomedical Ontology (OBO) Foundry and uses the Basic Formal Ontology (BFO) as an upper ontology. After providing a brief introduction to disposition types in BFO and IDO, we discuss three general techniques for representing combinations of dispositions under the headings blocking dispositions, complementary dispositions, and collective dispositions. Motivating examples for each combination of dispositions is given (...)
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  31. Bodily Systems and the Spatial-Functional Structure of the Human Body.Barry Smith - 2004 - Studies in Health and Technology Informatics 102:39–63.
    The human body is a system made of systems. The body is divided into bodily systems proper, such as the endocrine and circulatory systems, which are subdivided into many sub-systems at a variety of levels, whereby all systems and subsystems engage in massive causal interaction with each other and with their surrounding environments. Here we offer an explicit definition of bodily system and provide a framework for understanding their causal interactions. Medical sciences provide at best informal accounts of basic notions (...)
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  32. Interdisciplinary Workshop in the Philosophy of Medicine: Minds and Bodies in Medicine.Marion Godman & Elselijn Kingma - 2013 - Journal of Evaluation in Clinical Practice 19 (3):564-571.
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  33. Defining Quality of Care Persuasively.Maya J. Goldenberg - 2012 - Theoretical Medicine and Bioethics 33 (4):243-261.
    As the quality movement in health care now enters its fourth decade, the language of quality is ubiquitous. Practitioners, organizations, and government agencies alike vociferously testify their commitments to quality and accept numerous forms of governance aimed at improving quality of care. Remarkably, the powerful phrase ‘‘quality of care’’ is rarely defined in the health care literature. Instead it operates as an accepted and assumed goal worth pursuing. The status of evidence-based medicine, for instance, hinges on its ability to improve (...)
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  34. Wakefield & Exaptation.Andrew Howard - manuscript
    Wakefield requires all disorders to arise from the harmful failure of a naturally selected mechanism, but as exaptive traits do not appear to be the direct result of natural selection describing their failure as disorder is problematic. We will look at issues surrounding both biological exaptations and cultural exaptation, however, in dealing with cultural exaptation by explaining that the ‘harmful’ trait need not be identical to the failing mechanism upon which it is based, this creates further difficulties with his analysis. (...)
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  35. Causation in Medicine.Brendan Clarke - 2012 - In Wenceslao J. Gonzalez (ed.), Conceptual Revolutions: from Cognitive Science to Medicine. Netbiblo.
    In this paper, I offer one example of conceptual change. Specifically, I contend that the discovery that viruses could cause cancer represents an excellent example of branch jumping, one of Thagard’s nine forms of conceptual change. Prior to about 1960, cancer was generally regarded as a degenerative, chronic, non-infectious disease. Cancer causation was therefore usually held to be a gradual process of accumulating cellular damage, caused by relatively non-specific component causes, acting over long periods of time. Viral infections, on the (...)
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  36. Causality in Medicine with Particular Reference to the Viral Causation of Cancers.Brendan Clarke - 2011 - Dissertation, University College London
    In this thesis, I give a metascientific account of causality in medicine. I begin with two historical cases of causal discovery. These are the discovery of the causation of Burkitt’s lymphoma by the Epstein-Barr virus, and of the various viral causes suggested for cervical cancer. These historical cases then support a philosophical discussion of causality in medicine. This begins with an introduction to the Russo- Williamson thesis (RWT), and discussion of a range of counter-arguments against it. Despite these, I argue (...)
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  37. A Strategy for Improving and Integrating Biomedical Ontologies.Cornelius Rosse, Anand Kumar, Jose L. V. Mejino, Daniel L. Cook, Landon T. Detwiler & Barry Smith - 2005 - In Proceedings of the Annual Symposium of the American Medical Informatics Association. AMIA. pp. 639-643.
    The integration of biomedical terminologies is indispensable to the process of information integration. When terminologies are linked merely through the alignment of their leaf terms, however, differences in context and ontological structure are ignored. Making use of the SNAP and SPAN ontologies, we show how three reference domain ontologies can be integrated at a higher level, through what we shall call the OBR framework (for: Ontology of Biomedical Reality). OBR is designed to facilitate inference across the boundaries of domain ontologies (...)
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  38. Forms of Materialist Embodiment.Charles T. Wolfe - 2012 - In Matthew Landers & Brian Muñoz (eds.), Anatomy and the Organization of Knowledge, 1500-1850. Pickering & Chatto.
    The materialist approach to the body is often, if not always understood in ‘mechanistic’ terms, as the view in which the properties unique to organic, living embodied agents are reduced to or described in terms of properties that characterize matter as a whole, which allow of mechanistic explanation. Indeed, from Hobbes and Descartes in the 17th century to the popularity of automata such as Vaucanson’s in the 18th century, this vision of things would seem to be correct. In this paper (...)
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  39. Exposing the Vanities—and a Qualified Defense—of Mechanistic Reasoning in Health Care Decision Making.Jeremy Howick - 2011 - Philosophy of Science 78 (5):926-940.
    Philosophers of science have insisted that evidence of underlying mechanisms is required to support claims about the effects of medical interventions. Yet evidence about mechanisms does not feature on dominant evidence-based medicine “hierarchies.” After arguing that only inferences from mechanisms (“mechanistic reasoning”)—not mechanisms themselves—count as evidence, I argue for a middle ground. Mechanistic reasoning is not required to establish causation when we have high-quality controlled studies; moreover, mechanistic reasoning is more problematic than has been assumed. Yet where the problems can (...)
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1 — 50 / 111