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  1. Waddington redux: models and explanation in stem cell and systems biology.Melinda Bonnie Fagan - 2012 - Biology and Philosophy 27 (2):179-213.
    Stem cell biology and systems biology are two prominent new approaches to studying cell development. In stem cell biology, the predominant method is experimental manipulation of concrete cells and tissues. Systems biology, in contrast, emphasizes mathematical modeling of cellular systems. For scientists and philosophers interested in development, an important question arises: how should the two approaches relate? This essay proposes an answer, using the model of Waddington’s landscape to triangulate between stem cell and systems approaches. This simple abstract model represents (...)
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  • Philosophy in the Flesh: the Embodied Mind & its Challenge to Western Thought.George Lakoff (ed.) - 1999 - Basic Books.
    Reexamines the Western philosophical tradition, looking at the basic concepts of the mind, time, causation, morality, and the self.
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  • Visual Metaphor.Virgil C. Aldrich - 1968 - The Journal of Aesthetic Education 2 (1):73.
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  • The Euclidean Diagram.Kenneth Manders - 2008 - In Paolo Mancosu (ed.), The Philosophy of Mathematical Practice. Oxford, England: Oxford University Press. pp. 80--133.
    This chapter gives a detailed study of diagram-based reasoning in Euclidean plane geometry (Books I, III), as well as an exploration how to characterise a geometric practice. First, an account is given of diagram attribution: basic geometrical claims are classified as exact (equalities, proportionalities) or co-exact (containments, contiguities); exact claims may only be inferred from prior entries in the demonstration text, but co-exact claims may be asserted based on what is seen in the diagram. Diagram control by constructions is necessary (...)
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  • (1 other version)Landscapes, surfaces, and morphospaces: what are they good for?Massimo Pigliucci - 2012 - In Erik Svensson & Ryan Calsbeek (eds.), The Adaptive Landscape in Evolutionary Biology. Oxford University Press. pp. 26.
    Few metaphors in biology are more enduring than the idea of Adaptive Landscapes, originally proposed by Sewall Wright (1932) as a way to visually present to an audience of typically non- mathematically savvy biologists his ideas about the relative role of natural selection and genetic drift in the course of evolution. The metaphor, how- ever, was born troubled, not the least reason for which is the fact that Wright presented different diagrams in his original paper that simply can- not refer (...)
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  • Toward the rigorous use of diagrams in reasoning about hardware.Steven D. Johnson, Jon Barwise & Gerard Allwein - 1996 - In Gerard Allwein & Jon Barwise (eds.), Logical reasoning with diagrams. New York: Oxford University Press.
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  • Reprogramming cell fates: reconciling rarity with robustness.Sui Huang - 2009 - Bioessays 31 (5):546-560.
    The stunning possibility of “reprogramming” differentiated somatic cells to express a pluripotent stem cell phenotype (iPS, induced pluripotent stem cell) and the “ground state” character of pluripotency reveal fundamental features of cell fate regulation that lie beyond existing paradigms. The rarity of reprogramming events appears to contradict the robustness with which the unfathomably complex phenotype of stem cells can reliably be generated. This apparent paradox, however, is naturally explained by the rugged “epigenetic landscape” with valleys representing “preprogrammed” attractor states that (...)
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  • Structure‐Mapping: A Theoretical Framework for Analogy.Dedre Gentner - 1983 - Cognitive Science 7 (2):155-170.
    A theory of analogy must describe how the meaning of an analogy is derived from the meanings of its parts. In the structure‐mapping theory, the interpretation rules are characterized as implicit rules for mapping knowledge about a base domain into a target domain. Two important features of the theory are (a) the rules depend only on syntactic properties of the knowledge representation, and not on the specific content of the domains; and (b) the theoretical framework allows analogies to be distinguished (...)
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  • Diagrams as locality aids for explanation and model construction in cell biology.Nicholaos Jones & Olaf Wolkenhauer - 2012 - Biology and Philosophy 27 (5):705-721.
    Using as case studies two early diagrams that represent mechanisms of the cell division cycle, we aim to extend prior philosophical analyses of the roles of diagrams in scientific reasoning, and specifically their role in biological reasoning. The diagrams we discuss are, in practice, integral and indispensible elements of reasoning from experimental data about the cell division cycle to mathematical models of the cycle’s molecular mechanisms. In accordance with prior analyses, the diagrams provide functional explanations of the cell cycle and (...)
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  • Diagrams in mathematics: history and philosophy.John Mumma & Marco Panza - 2012 - Synthese 186 (1):1-5.
    Diagrams are ubiquitous in mathematics. From the most elementary class to the most advanced seminar, in both introductory textbooks and professional journals, diagrams are present, to introduce concepts, increase understanding, and prove results. They thus fulfill a variety of important roles in mathematical practice. Long overlooked by philosophers focused on foundational and ontological issues, these roles have come to receive attention in the past two decades, a trend in line with the growing philosophical interest in actual mathematical practice.
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  • (2 other versions)On the Very Idea of a Conceptual Scheme.Donald Davidson - 1973 - Proceedings and Addresses of the American Philosophical Association 47:5-20.
    Davidson attacks the intelligibility of conceptual relativism, i.e. of truth relative to a conceptual scheme. He defines the notion of a conceptual scheme as something ordering, organizing, and rendering intelligible empirical content, and calls the position that employs both notions scheme-content dualism. He argues that such dualism is untenable since: not only can we not parcel out empirical content sentence per sentence but also the notion of uninterpreted content to which several schemes are relative, and the related notion of a (...)
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  • Visual Representations and Confirmation.Laura Perini - 2005 - Philosophy of Science 72 (5):913-926.
    Publications in contemporary science journals often include figures like graphs, diagrams, photographs, and MRIs, which are presented as support for the hypothesis the author is defending. As a first step to explaining how figures contribute to confirmation, I present an account of visual representation and use examples to show how the visual format is involved in the support those figures provide the authors’ conclusions. I then show that attempts to explain what figures contribute to scientific arguments without analyzing them as (...)
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  • The Truth in Pictures.Laura Perini - 2005 - Philosophy of Science 72 (1):262-285.
    Scientists typically use a variety of representations, including different kinds of figures, to present and defend hypotheses. In order to understand the justification of scientific hypotheses, it is essential to understand how visual representations contribute to scientific arguments. Since the logical understanding of arguments involves the truth or falsity of the representations involved, visual representations must have the capacity to bear truth in order to be genuine components of arguments. By drawing on Goodman's analysis of symbol systems, and on Tarski's (...)
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  • Metaphor and Theory Change.Richard N. Boyd - 1993 - In Andrew Ortony (ed.), Metaphor and Thought. Cambridge University Press.
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  • Logical reasoning with diagrams.Gerard Allwein & Jon Barwise (eds.) - 1996 - New York: Oxford University Press.
    One effect of information technology is the increasing need to present information visually. The trend raises intriguing questions. What is the logical status of reasoning that employs visualization? What are the cognitive advantages and pitfalls of this reasoning? What kinds of tools can be developed to aid in the use of visual representation? This newest volume on the Studies in Logic and Computation series addresses the logical aspects of the visualization of information. The authors of these specially commissioned papers explore (...)
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  • Epigenetic landscaping: Waddington's use of cell fate bifurcation diagrams. [REVIEW]Scott F. Gilbert - 1991 - Biology and Philosophy 6 (2):135-154.
    From the 1930s through the 1970s, C. H. Waddington attempted to reunite genetics, embryology, and evolution. One of the means to effect this synthesis was his model of the epigenetic landscape. This image originally recast genetic data in terms of embryological diagrams and was used to show the identity of genes and inducers and to suggest the similarities between embryological and genetic approaches to development. Later, the image became more complex and integrated gene activity and mutations. These revised epigenetic landscapes (...)
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  • (1 other version)Models and Metaphors: Studies in Language and Philosophy.Max Black - 1962 - Ithaca, N.Y.,: Cornell University Press.
    Author Max Black argues that language should conform to the discovered regularities of experience it is radically mistaken to assume that the conception of language is a mirror of reality.
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  • (1 other version)Models and Analogies in Science.Mary B. Hesse - 1966 - Philosophy and Rhetoric 3 (3):190-191.
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  • Aesthetics: Problems in the Philosophy of Criticism.Monroe C. Beardsley - 1958 - Philosophy 36 (136):80-81.
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  • The Emergence of Thought.Donald Davidson - 1999 - Erkenntnis 51 (1):511-521.
    A phenomenon “emerges” when a concept is instantiated for the first time: hence emergence is relative to a set of concepts. Propositional thought and language emerge together. It is proposed that the degree of complexity of an object language relative to a given metalanguage can be gauged by the number of ways it can be translated into that metalanguage: in analogy with other forms of measurement, the more ways the object language can be translated into the metalanguage, the less powerful (...)
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  • (1 other version)Metaphor.Max Black - 1954-1955 - Proceedings of the Aristotelian Society 55:273-294.
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  • The Emergence of a Visual Language for Geological Science 1760—1840.Martin J. S. Rudwick - 1976 - History of Science 14 (3):149-195.
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  • Art and its Objects.Richard Wollheim - 1968 - Cambridge, United Kingdom: Cambridge University Press. Edited by Richard Thomas Eldridge.
    Richard Wollheim's classic reflection on art considers central questions regarding expression, representation, style, the significance of the artist's intention and the essentially historical nature of art. Presented in a fresh series livery for the twenty-first century, with a specially commissioned preface written by Richard Eldridge, illuminating its continuing importance and relevance to philosophical enquiry, Art and its Objects continues to be a perceptive and engaging introduction to the questions and philosophical issues raised by works of art and the part they (...)
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  • Operational constraints in diagrammatic reasoning.Atsushi Shimojima - 1996 - In Gerard Allwein & Jon Barwise (eds.), Logical reasoning with diagrams. New York: Oxford University Press.
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  • Why a Diagram is (Sometimes) Worth Ten Thousand Words.Jill H. Larkin & Herbert A. Simon - 1987 - Cognitive Science 11 (1):65-100.
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  • Truth-bearers or truth-makers?Laura Perini - 2012 - Spontaneous Generations 6 (1):142-147.
    One way visual representations might function in scientific reasoning is to convey content that is true or false, analogous to making a claim. An alternative way that visual representations might function is as an object that may make statements true or false, but is not itself true or false, analogous to a scientific model. In this paper I evaluate the most recent and extended defense of this latter position and show that the case study involved does not in fact support (...)
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  • Pictorial speech acts.Søren Kjørup - 1978 - Erkenntnis 12 (1):55 - 71.
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  • (2 other versions)Languages of Art: An Approach to a Theory of Symbols.Nelson Goodman - 1971 - British Journal for the Philosophy of Science 22 (2):187-198.
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  • The epigenetic landscape in the course of time: Conrad Hal Waddington’s methodological impact on the life sciences.Jan Baedke - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):756-773.
    It seems that the reception of Conrad Hal Waddington’s work never really gathered speed in mainstream biology. This paper, offering a transdisciplinary survey of approaches using his epigenetic landscape images, argues that (i) Waddington’s legacy is much broader than is usually recognized—it is widespread across the life sciences (e.g. stem cell biology, developmental psychology and cultural anthropology). In addition, I will show that (ii) there exist as yet unrecognized heuristic roles, especially in model building and theory formation, which Waddington’s images (...)
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  • (1 other version)Understanding Pictures.Domenic Lopes - 2000 - Mind 109 (433):158-162.
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  • (2 other versions)Languages of Art. An Approach to a Theory of Symbols.Nelson Goodman - 1970 - Critica 4 (11/12):164-171.
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  • Metaphors We Live By.George Lakoff & Mark Johnson - 1980 - Ethics 93 (3):619-621.
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  • Multimodal Metaphor.Eduardo Urios-Aparisi & Charles J. Forceville (eds.) - 2009 - Mouton de Gruyter.
    Metaphor pervades discourse and may govern how we think and act. But most studies only discuss its verbal varieties. This book examines metaphors drawing on combinations of visuals, language, gestures, sound, and music. Investigated texts include advertising, political cartoons, comics, film, songs, and oral communication. Where appropriate, the influence of genre and cultural factors is thematized.
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  • Tools for Thought.Conrad Hal Waddington - 1977 - Jonathan Cape.
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  • Making the Visual Visible in Philosophy of Science.Annamaria Carusi - 2012 - Spontaneous Generations 6 (1):106-114.
    As data-intensive and computational science become increasingly established as the dominant mode of conducting scientific research, visualisations of data and of the outcomes of science become increasingly prominent in mediating knowledge in the scientific arena. This position piece advocates that more attention should be paid to the epistemological role of visualisations beyond their being a cognitive aid to understanding, but as playing a crucial role in the formation of evidence for scientific claims. The new generation of computational and informational visualisations (...)
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  • Human diagrammatic reasoning and seeing-as.Annalisa Coliva - 2012 - Synthese 186 (1):121-148.
    The paper addresses the issue of human diagrammatic reasoning in the context of Euclidean geometry. It develops several philosophical categories which are useful for a description and an analysis of our experience while reasoning with diagrams. In particular, it draws the attention to the role of seeing-as; it analyzes its implications for proofs in Euclidean geometry and ventures the hypothesis that geometrical judgments are analytic and a priori, after all.
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  • (1 other version)Material Models in Biology.James R. Griesemer - 1990 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1990:79 - 93.
    Propositions alone are not constitutive of science. But is the "non-propositional" side of science theoretically superfluous: must philosophy of science consider it in order to adequately account for science? I explore the boundary between the propositional and non-propositional sides of biological theory, drawing on three cases: Grinnell's remnant models of faunas, Wright's path analysis, and Weismannism's role in the generalization of evolutionary theory. I propose a picture of material model-building in biology in which manipulated systems of material objects function as (...)
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  • Must scientific diagrams be eliminable? The case of path analysis.James R. Griesemer - 1991 - Biology and Philosophy 6 (2):155-180.
    Scientists use a variety of modes of representation in their work, but philosophers have studied mainly sentences expressing propositions. I ask whether diagrams are mere conveniences in expressing propositions or whether they are a distinct, ineliminable mode of representation in scientific texts. The case of path analysis, a statistical method for quantitatively assessing the relative degree of causal determination of variation as expressed in a causal path diagram, is discussed. Path analysis presents a worst case for arguments against eliminability since (...)
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  • Meaning and Truth in the Arts.John Hospers - 1947 - Philosophy 22 (83):283-284.
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  • (1 other version)Are Pictures Really Necessary? The Case of Sewell Wright's "Adaptive Landscapes".Michael Ruse - 1990 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1990:63 - 77.
    Philosophical analyses of science tend to ignore illustrations, implicitly regarding them as theoretically dispensible. If challenged, it is suggested that such neglect is justifiable, because the use of illustrations only leads to faulty reasoning, and thus is the mark of bad or inadequate science. I take as an example one of the most famous illustrations in the history of evolutionary biology, and argue that the philosophers' scorn is without foundation. I take my conclusions to be support for a naturalistic approach (...)
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  • Knowing with images: Medium and message.John Kulvicki - 2010 - Philosophy of Science 77 (2):295-313.
    Problems concerning scientists’ uses of representations have received quite a bit of attention recently. The focus has been on how such representations get their contents and on just what those contents are. Less attention has been paid to what makes certain kinds of scientific representations different from one another and thus well suited to this or that epistemic end. This article considers the latter question with particular focus on the distinction between images and graphs on the one hand and descriptions (...)
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  • Explanation in two dimensions: Diagrams and biological explanation.Laura Perini - 2005 - Biology and Philosophy 20 (2-3):257-269.
    Molecular biologists and biochemists often use diagrams to present hypotheses. Analysis of diagrams shows that their content can be expressed with linguistic representations. Why do biologists use visual representations instead? One reason is simple comprehensibility: some diagrams present information which is readily understood from the diagram format, but which would not be comprehensible if the same information was expressed linguistically. But often diagrams are used even when concise, comprehensible linguistic alternatives are available. I explain this phenomenon by showing why diagrammatic (...)
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  • (1 other version)Understanding Pictures.Dominic Lopes - 1999 - Philosophical Quarterly 49 (196):398-400.
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  • Chapter 10. Visual metaphoric conceptualization in editorial cartoons.Eduardo Urios-Aparisi & Charles J. Forceville - 2009 - In Eduardo Urios-Aparisi & Charles J. Forceville (eds.), Multimodal Metaphor. Mouton de Gruyter.
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  • Organisers and Genes.C. H. Waddington - 1941 - Philosophy of Science 8 (3):463-463.
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  • The Heuristic Role of Sewall Wright’s 1932 Adaptive Landscape Diagram.Robert A. Skipper - 2004 - Philosophy of Science 71 (5):1176-1188.
    Sewall Wright's adaptive landscape is the most influential heuristic in evolutionary biology. Wright's biographer, Provine, criticized Wright's adaptive landscape, claiming that its heuristic value is dubious because of deep flaws. Ruse has defended Wright against Provine. Ruse claims Provine has not shown Wright's use of the landscape is flawed, and that, even if it were, it is heuristically valuable. I argue that both Provine's and Ruse's analyses of the adaptive landscape are defective and suggest a more adequate understanding of it.
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  • The Colour of Risk: An Exploration of the IPCC’s “Burning Embers” Diagram.Martin Mahony - 2012 - Spontaneous Generations 6 (1):75-89.
    This article tracks the historical emergence of a new visual convention in the representation of the risks associated with climate change. The “reasons for concern” or “burning embers” diagram has become a prominent visual element of the climate change debate. By drawing on a number of cultural resources, the image has gained a level of discursive power which has resulted both in material mobility and epistemic transformation as the diagram itself has become a tool for a variety of actors to (...)
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