Within the philosophy of science, the realism debate has been revitalised by the development of forms of structural realism. These urge a shift in focus from the object oriented ontologies that come and go through the history of science to the structures that remain through theory change. Such views have typically been elaborated in the context of theories of physics and are motivated by, first of all, the presence within such theories of mathematical equations that allow straightforward representation of the (...) relevant structures; and secondly, the implications of such theories for the individuality and identity of putative objects. My aim in this talk is to explore the possibility of extending such views to biological theories. An obvious concern is that within the context of the latter it is typically insisted that we cannot find the kinds of highly mathematised structures that structural realism can point to in physics. I shall indicate how the model-theoretic approach to theories might help allay such concerns. Furthermore, issues of identity and individuality also arise within biology. Thus Dupre has recently noted that there exists a ‘General Problem of Biological Individuality’ which relates to the issue of how one divides ‘massively integrated and interconnected’ systems into discrete components. In response Dupre advocates a form of ‘Promiscuous Realism’ that holds, for example, that there is no unique way of dividing the phylogenetic tree into kinds. Instead I shall urge serious consideration of those aspects of the work of Dupre and others that lean towards a structuralist interpretation. By doing so I hope to suggest possible ways in which a structuralist stance might be extended to biology. (shrink)

This paper argues for a metaphysics of relations based on a characterization of quantum entanglement in terms of non-separability, thereby regarding entanglement as a sort of holism. By contrast to a radical metaphysics of relations, the position set out in this paper recognizes things that stand in the relations, but claims that, as far as the relations are concerned, there is no need for these things to have qualitative intrinsic properties underlying the relations. This position thus opposes a metaphysics of (...) individual things that are characterized by intrinsic properties. A principal problem of the latter position is that it seems that we cannot gain any knowledge of these properties insofar as they are intrinsic. Against this background, the rationale behind a metaphysics of relations is to avoid a gap between epistemology and metaphysics. (shrink)

According to structural realism, in mature science there is structural continuity along theoretical change. A major counterexample to this thesis is the transition from the Eightfold Way to the Standard Model in particle physics. Nevertheless, the notion of structure is significantly important in comprehending the theoretical picture of particle physics, where particles change and undergo transmutations, while the only thing which remains unchanged is the basic structure, i.e. the symmetry group which controls the transmutations. This kind of view agrees with (...) the paradigmatic case where the structure is an internal symmetry and the instantiations are the elementary particles. The metaphysical view which reflects this situation is a version of ontic structuralism. (shrink)

We reconsider the Nagelian theory of reduction and argue that, contrary to a widely held view, it is the right analysis of intertheoretic reduction. The alleged difficulties of the theory either vanish upon closer inspection or turn out to be substantive philosophical questions rather than knock-down arguments.

How do we go about weighing evidence, testing hypotheses, and making inferences? According to the model of _Inference to the Best Explanation_, we work out what to infer from the evidence by thinking about what would actually explain that evidence, and we take the ability of a hypothesis to explain the evidence as a sign that the hypothesis is correct. In _Inference to the Best Explanation_, Peter Lipton gives this important and influential idea the development and assessment it deserves. The (...) second edition has been substantially enlarged and reworked, with a new chapter on the relationship between explanation and Bayesianism, and an extension and defence of the account of contrastive explanation. It also includes an expanded defence of the claims that our inferences really are guided by diverse explanatory considerations, and that this pattern of inference can take us towards the truth. This edition of _Inference to the Best Explanation_ has also been updated throughout and includes a new bibliography. (shrink)

Species in biology are traditionally perceived as kinds of organisms about which explanatory and predictive generalizations can be made, and biologists commonly use species in this manner. This perception of species is, however, in stark contrast with the currently accepted view that species are not kinds or classes at all, but individuals. In this paper I investigate the conditions under which the two views of species might be held simultaneously. Specifically, I ask whether upon acceptance of an ontology of species (...) as diachronic segments of the tree of life species can perform the epistemic role of kinds of organisms to which explanatory and predictive generalizations apply. I show that, for species-level segments of the tree of life, several requirements have to be met before the performance of this epistemic role is possible, and I argue that these requirements can be met by defining species according to the Composite Species Concept proposed by Kornet and McAllister in the 1990s. (shrink)

The concept of mechanism is analyzed in terms of entities and activities, organized such that they are productive of regular changes. Examples show how mechanisms work in neurobiology and molecular biology. Thinking in terms of mechanisms provides a new framework for addressing many traditional philosophical issues: causality, laws, explanation, reduction, and scientific change.

With the advent of the Human Genome Project there have been many claims for the genetic origins of complex human behavior including insanity, criminality, and intelligence. But what does it really mean to call something 'genetic'? This is the fundamental question that Sahotra Sarkar's book addresses. The author analyses the nature of reductionism in classical and molecular genetics. He shows that there are two radically different kinds of reductionist explanation: genetic reduction (as found in classical genetics) and physical reduction (found (...) in molecular genetics). This important book clarifies the meaning of the term 'genetic', shows how molecular studies have affected genetics, and provides the philosophical background necessary to understand the debates over the Human Genome Project. It will be of particular interest to professionals and students in the philosophy of science, the history of science, and the social studies of science, medicine, and technology. (shrink)

The claim of the multiple realizability of mental states by brain states has been a major feature of the dominant philosophy of mind of the late 20th century. The claim is usually motivated by evidence that mental states are multiply realized, both within humans and between humans and other species. We challenge this contention by focusing on how neuroscientists differentiate brain areas. The fact that they rely centrally on psychological measures in mapping the brain and do so in a comparative (...) fashion undercuts the likelihood that, at least within organic life forms, we are likely to find cases of multiply realized psychological functions. (shrink)

The no-miracles argument for realism and the pessimistic meta-induction for anti-realism pull in opposite directions. Structural Realism---the position that the mathematical structure of mature science reflects reality---relieves this tension.

I examine different arguments that could be used to establish indeterminism of neurological processes. Even though scenarios where single events at the molecular level make the difference in the outcome of such processes are realistic, this falls short of establishing indeterminism, because it is not clear that these molecular events are subject to quantum mechanical uncertainty. Furthermore, attempts to argue for indeterminism autonomously (i.e., independently of quantum mechanics) fail, because both deterministic and indeterministic models can account for the empirically observed (...) behavior of ion channels. (shrink)

Recent discussion of the statistical character of evolutionary theory has centered around two positions: (1) Determinism combined with the claim that the statistical character is eliminable, a subjective interpretation of probability, and instrumentalism; (2) Indeterminism combined with the claim that the statistical character is ineliminable, a propensity interpretation of probability, and realism. I point out some internal problems in these positions and show that the relationship between determinism, eliminability, realism, and the interpretation of probability is more complex than previously assumed (...) in this debate. Furthermore, I take some initial steps towards a more adequate account of the statistical character of evolutionary theory. (shrink)

Recent discussion of the statistical character of evolutionary theory has centered around two positions: Determinism combined with the claim that the statistical character is eliminable, a subjective interpretation of probability, and instrumentalism; Indeterminism combined with the claim that the statistical character is ineliminable, a propensity interpretation of probability, and realism. I point out some internal problems in these positions and show that the relationship between determinism, eliminability, realism, and the interpretation of probability is more complex than previously assumed in this (...) debate. Furthermore, I take some initial steps towards a more adequate account of the statistical character of evolutionary theory. (shrink)

Former discussions of biological generalizations have focused on the question of whether there are universal laws of biology. These discussions typically analyzed generalizations out of their investigative and explanatory contexts and concluded that whatever biological generalizations are, they are not universal laws. The aim of this paper is to explain what biological generalizations are by shifting attention towards the contexts in which they are drawn. I argue that within the context of any particular biological explanation or investigation, biologists employ two (...) types of generations. One type identifies causal regularities exhibited by particular kinds of biological entities. The other type identifies how these entities are distributed in the biological world. (shrink)

According to Aristotelian essentialism, the nature of an organism is constituted of a particular goal-directed disposition to produce an organism typical of its kind. This paper argues—against the prevailing orthodoxy—that essentialism of this sort is indispensable to evolutionary biology. The most powerful anti-essentialist arguments purport to show that the natures of organisms play no explanatory role in modern synthesis biology. I argue that recent evolutionary developmental biology provides compelling evidence to the contrary. Developmental biology shows that one must appeal to (...) the capacities of organisms to explain what makes adaptive evolution adaptive. Moreover, the specific capacities in question are precisely those that, according to Aristotle, constitute the nature of an organism. Essentialism 1.1 Aristotelian biological kinds Evolutionary anti-essentialism 2.1 Taxonomic anti-essentialism 2.2 Explanatory anti-essentialism Adaptation 3.1 Stability 3.2 Mutability 3.3 Phenotypic plasticity and adaptive evolution The natures of organisms Conclusion. (shrink)

Suppe, F. The search for philosophic understanding of scientific theories (p. [1]-241)--Proceedings of the symposium.--Bibliography, compiled by Rew A. Godow, Jr. (p. [615]-646).

The positivistic Received View construed scientific theories syntactically as axiomatic calculi where theoretical terms were given a partial semantic interpretation via correspondence rules connecting them to observation statements. This paper assesses what, with hindsight, seem the most important defects in the Received View; surveys the main proposed successor analyses to the Received View--various Semantic Conception versions and the Structuralist Analysis; evaluates how well they avoid those defects; examines what new problems they face and where the most promising require further development (...) or leave unanswered questions; explores implications of recent work on models for understanding theories; and rebuts the few criticisms of the Semantic Conception that have surfaced. (shrink)

According to principles of probability coordination, such as Miller's Principle or Lewis's Principal Principle, you ought to set your subjective probability for an event equal to what you take to be the objective probability of the event. For example, you should expect events with a very high probability to occur and those with a very low probability not to occur. This paper examines the grounds of such principles. It is argued that any attempt to justify a principle of probability coordination (...) encounters the same difficulties as attempts to justify induction. As a result, no justification can be found. (shrink)

The present paper studies a specific way of addressing the question whether the laws involving the basic constituents of nature are statistical. While most German physicists, above all Planck, treated the issues of determinism and causality within a Kantian framework, the tradition which I call Vienna Indeterminism began from Mach’s reinterpretation of causality as functional dependence. This severed the bond between causality and realism because one could no longer avail oneself of a priori categories as a criterion for empirical reality. (...) Hence, an independent reality criterion had to be sought, a problem which all three physicists to be studied solved in different ways that were mainly conditioned by their different concepts of probability. In order to prevent a dissipation of intuited facts, Mach had to resort to a principle of unique determination as his reality criterion, especially when discussing the Principle of Least Action. Giving theories more independence, Boltzmann understood atomism as property reduction to precisely defined theoretical entities and their interactions. While this served as a relative reality criterion, he also advocated a constructivist one because atomism was already implied by our finitary reasoning power. Finally, Exner contemplated the idea that all apparently deterministic laws are only a macroscopic limit of an irreducible indeterminism, because by adopting the frequency interpretation, observable collectives could be considered as the real basic entities. (shrink)

Critics of the ideal of value‐free science often assume that they must reject the distinction between epistemic and nonepistemic values. I argue that this assumption is mistaken and that the distinction can be used to clarify and defend the argument from inductive risk, which challenges the value‐free ideal. I develop the idea that the characteristic feature of epistemic values is that they promote, either intrinsically or extrinsically, the attainment of truths. This proposal is shown to answer common objections to the (...) distinction and provide a principled basis for separating legitimate from illegitimate influences of nonepistemic values in scientific inference. *Received June 2009; revised September 2009. †To contact the author, please write to: 503 S. Kedzie Hall, Michigan State University, East Lansing, MI 48824‐1032; e‐mail: [email protected]. (shrink)

This paper is structured around the three elements of the title. Section 2 claims that (a) structures need objects and (b) scientific structuralism should focus on in re structures. Therefore, pure structuralism is undermined. Section 3 discusses whether the world has `excess structure' over the structure of appearances. The main point is that the claim that only structure can be known is false. Finally, Section 4 argues directly against ontic structural realism that it lacks the resources to accommodate causation within (...) its structuralist slogan. (shrink)

"Science is rooted in conversations," wrote Werner Heisenberg, one of the twentieth century's great physicists. In Quantum Dialogue, Mara Beller shows that science is rooted not just in conversation but in disagreement, doubt, and uncertainty. She argues that it is precisely this culture of dialogue and controversy within the scientific community that fuels creativity. Beller draws her argument from her radical new reading of the history of the quantum revolution, especially the development of the Copenhagen interpretation. One of several competing (...) approaches, this version succeeded largely due to the rhetorical skills of Niels Bohr and his colleagues. Using extensive archival research, Beller shows how Bohr and others marketed their views, misrepresenting and dismissing their opponents as "unreasonable" and championing their own not always coherent or well-supported position as "inevitable." Quantum Dialogue, winner of the 1999 Morris D. Forkosch Prize of the Journal of the History of Ideas, will fascinate everyone interested in how stories of "scientific revolutions" are constructed and "scientific consensus" achieved. "[A]n intellectually stimulating piece of work, energised by a distinct point of view."—Dipankar Home, Times Higher Education Supplement "[R]emarkable and original. . . . [Beller's] arguments are thoroughly supported and her conclusions are meticulously argued. . . . This is an important book that all who are interested in the emergence of quantum mechanics will want to read."—William Evenson, History of Physics Newsletter. (shrink)

Several authors have argued that higher taxa are monophyletic homeostatic property cluster natural kinds. On the traditional definition of monophyly, this will not work: the emergence of taxon-defining homeostatic property clusters would not always correspond to unique speciation events. An alternative conception of monophyly is developed and advocated, which can accommodate the homeostatic property cluster proposal. Recent work in philosophy of science shows that it meets appropriate standards of objectivity and precision.

A set of hypotheses is formulated for a connectionist approach to cognitive modeling. These hypotheses are shown to be incompatible with the hypotheses underlying traditional cognitive models. The connectionist models considered are massively parallel numerical computational systems that are a kind of continuous dynamical system. The numerical variables in the system correspond semantically to fine-grained features below the level of the concepts consciously used to describe the task domain. The level of analysis is intermediate between those of symbolic cognitive models (...) and neural models. The explanations of behavior provided are like those traditional in the physical sciences, unlike the explanations provided by symbolic models. (shrink)

Are people rational? This question was central to Greek thought and has been at the heart of psychology and philosophy for millennia. This book provides a radical and controversial reappraisal of conventional wisdom in the psychology of reasoning, proposing that the Western conception of the mind as a logical system is flawed at the very outset. It argues that cognition should be understood in terms of probability theory, the calculus of uncertain reasoning, rather than in terms of logic, the calculus (...) of certain reasoning. (shrink)

Can there be good reasons for judging one set of probabilistic assertions more reliable than a second? There are many candidates for measuring "goodness" of probabilistic forecasts. Here, I focus on one such aspirant: calibration. Calibration requires an alignment of announced probabilities and observed relative frequency, e.g., 50 percent of forecasts made with the announced probability of.5 occur, 70 percent of forecasts made with probability.7 occur, etc. To summarize the conclusions: (i) Surveys designed to display calibration curves, from which a (...) recalibration is to be calculated, are useless without due consideration for the interconnections between questions (forecasts) in the survey. (ii) Subject to feedback, calibration in the long run is otiose. It gives no ground for validating one coherent opinion over another as each coherent forecaster is (almost) sure of his own long-run calibration. (iii) Calibration in the short run is an inducement to hedge forecasts. A calibration score, in the short run, is improper. It gives the forecaster reason to feign violation of total evidence by enticing him to use the more predictable frequencies in a larger finite reference class than that directly relevant. (shrink)

Leslie Graves, Barbara Horan and Alex Rosenberg (1999) have argued that the process of evolution is really deterministic, so we should be instrumentalists about our probabilistic evolutionary theory. I criticize the consistency of their view. I argue that because they are realists towards multiple theories (quantum mechanics and macrophysics) their arguments against realism for another scientific theory fail. The main point of this paper is critical, but in order to set up this criticism I explore the ramifications of realism for (...) multiple theories. Finally, I offer a brief metaphysical justification for realism about multiple theories. This view justifies realism for evolutionary theory, which has been defended by Robert Brandon and Scott Carson (1996). (shrink)

Many have claimed that unspecific evidence sometimes demands unsharp, indeterminate, imprecise, vague, or interval-valued probabilities. Against this, a variant of the diachronic Dutch Book argument shows that perfectly rational agents always have perfectly sharp probabilities.

The question of the relationship of the making of value judgments in a typically ethical sense to the methods and procedures of science has been discussed in the literature at least to that point which e. e. cummings somewhere refers to as “The Mystical Moment of Dullness.” Nevertheless, albeit with some trepidation, I feel that something more may fruitfully be said on the subject.

In this paper it is argued that qualitative theories (Q-theories) can be used to describe the statistical structure of cross classified populations and that the notion of verisimilitude provides an appropriate tool for measuring the statistical adequacy of Q-theories. First of all, a short outline of the post-Popperian approaches to verisimilitude and of the related verisimilitudinarian non-falsificationist methodologies (VNF-methodologies) is given. Secondly, the notion of Q-theory is explicated, and the qualitative verisimilitude of Q-theories is defined. Afterwards, appropriate measures for the (...) statistical verisimilitude of Q-theories are introduced, so to obtain a clear formulation of the intuitive idea that the statistical truth about cross classified populations can be approached by falsified Q-theories. Finally, it is argued that some basic intuitions underlying VNF-methodologies are shared by the so-called prediction logic, developed by the statisticians and social scientists David K. Hildebrand, James D. Laing and Howard Rosenthal. (shrink)

We present a precise form of structural realism, called group structural realism , which identifies ‘structure’ in quantum theory with symmetry groups. However, working out the details of this view actually illuminates a major problem for structural realism; namely, a structure can itself have structure. This article argues that, once a precise characterization of structure is given, the ‘metaphysical hierarchy’ on which group structural realism rests is overly extravagant and ultimately unmotivated.

The architects of the modern synthesis banned essentialism from evolutionary theory. This rejection of essentialism was motivated by Darwin’s theory of natural selection, and the continuity of evolutionary transformation. Contemporary evolutionary biology witnesses a renaissance of essentialism in three contexts: “origin essentialism” with respect to species and supraspecific taxa, the bar coding of species on the basis of discontinuities of DNA variation between populations, and the search for laws of evolutionary developmental biology. Such “new essentialism” in contemporary biology must be (...) of a new kind that accommodates relational (extrinsic) properties as historical essences and cluster concepts of natural kinds. (shrink)

According to a recent suggestion, the names of gene taxa should be conceived of as referring to individuals with concrete genes as their parts, just as the names of biological species are often understood as denoting individuals with organisms as their parts. Although prima facie this suggestion might advance the debate on gene concepts in a similar way as the species-are-individuals thesis advanced the debate on species concepts, I argue that the principal arguments in support of the gene-individuality thesis are (...) much less compelling than the parallel arguments in the species case. In addition, I argue that the notion of biological function invoked in the gene-individuality thesis (selected effect) is not the one that biologists actually use when individuating genes. Contra the gene-individuality thesis, I argue that gene names refer to kinds, defined primarily (though not exclusively) by causal-role functions. (shrink)