Results for 'Biofilm, Bacterial infections, Antibiotic resistance, Plasmids'

989 found
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  1. Bacterial Biofilm and its Clinical Implications.Prof Shakibaie - 2018 - Ann Microbiol Res 2 (1):45-50.
    Microbial biofilm created huge burden in treatment of both community and hospital infections. A biofilm is complex communities of bacteria attached to a surface or interface enclosed in an exopolysaccharide matrix and protected from unfavorable conditions such as presence of antibiotics, host defense or oxidative stresses. Biofilms are often considered hot spot for horizontal gene transfer among same or different bacterial species. Furthermore, bacteria with increased hydrophobicity facilitate biofilm formation by reducing repulsion between the extracellular matrix and the bacterium. (...)
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  2.  65
    Effect of antimicrobial susceptibility testing on treating Libyan outpatients with a suspected bacterial infection.Abdallah A. Mahjoub - 2024 - Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 4 (3):41-50.
    Clinical microbiology serves as a partner to clinicians in the diagnosis and treatment of infectious diseases. Antibiotics are prescribed empirically before the availability of antimicrobial susceptibility testing data, especially when the patient's medical status could deteriorate by suspending the treatment. To investigate the impact of antimicrobial susceptibility testing on the management of outpatients with suspected bacterial infection in Libyan patients, a cross-sectional prospective study concluded on microbial microdroplet culture by including outpatients with suspected bacterial infection, who have done (...)
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  3. The Future of Phage: Ethical challenges of using phage viruses to treat bacterial infections.Jonathan Anomaly - 2020 - Public Health Ethics 13.
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  4. Emergence of Ciprofloxacin Resistance among Pseudomonas Aeruginosa Isolated from Burn Patients [hplimg].M. R. Shakibaie, S. Adeli & Y. Nikian - 2001 - Emergence: Complexity and Organization 26 (3&4).
    Background: Increasing resistance of Pseudomonas aeruginosa to ciprofloxacin in ICU/burn units has created a problem in the treatment of infections caused by this microorganism. -/- Methods: Fifty P. aeruginosa strains were isolated from burn patients hospitalized in the Kerman Hospital during May 1999-April 2000 and were tested for in-vitro sensitivity to different antibiotics by disc diffusion breakpoint assay. The isolates were subjected to minimum inhibitory concentration (MIC) test by agar dilution method. Existence of the plasmids was also investigated in (...)
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  5. Love in the Time of Antibiotic Resistance: How Altruism Might Be Our Best Hope.Dien Ho - 2017 - In Philosophical Issues in Pharmaceutics: Development, Dispensing, and Use. Dordrecht: Springer.
    Antibiotic-resistant bacteria pose a serious threat to our health. Our ability to destroy deadly bacteria by using antibiotics have not only improved our lives by curing infections, it also allows us to undertake otherwise dangerous treatments from chemotherapies to invasive surgeries. The emergence of antibiotic resistance, I argue, is a consequence of various iterations of prisoner’s dilemmas. To wit, each participant (from patients to nations) has rational self-interest to pursue a course of action that is suboptimal for all (...)
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  6.  86
    Effect of antimicrobial susceptibility testing on treating Libyan outpatients with a suspected bacterial infection.Abdallah A. Mahjoub - 2024 - Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 4 (3):41-50.
    Clinical microbiology serves as a partner to clinicians in the diagnosis and treatment of infectious diseases. Antibiotics are prescribed empirically before the availability of antimicrobial susceptibility testing data, especially when the patient's medical status could deteriorate by suspending the treatment. To investigate the impact of antimicrobial susceptibility testing on the management of outpatients with suspected bacterial infection in Libyan patients, a cross-sectional prospective study concluded on microbial microdroplet culture by including outpatients with suspected bacterial infection, who have done (...)
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  7. Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology.J. A. Shapiro - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (4):807-819.
    Forty years’ experience as a bacterial geneticist has taught me that bacteria possess many cognitive, computational and evolutionary capabilities unimaginable in the first six decades of the twentieth century. Analysis of cellular processes such as metabolism, regulation of protein synthesis, and DNA repair established that bacteria continually monitor their external and internal environments and compute functional outputs based on information provided by their sensory apparatus. Studies of genetic recombination, lysogeny, antibiotic resistance and my own work on transposable elements (...)
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  8. Combating Resistance: The Case for a Global Antibiotics Treaty.Jonny Anomaly - 2010 - Public Health Ethics 3 (1):13-22.
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  9.  61
    Advancements and challenges in the medical treatment of monkeypox: A recent focused review.Hamza M. Alasbily - 2024 - Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 4 (3):51-56.
    Monkeypox, an infectious disease caused by the Orthopoxvirus, was identified in humans in 1970. It has recently emerged as a global health concern due to outbreaks beyond its endemic regions in Central and West Africa. This review examines the current state of medical treatments for monkeypox as of 2024, focusing on antiviral agents, immunotherapies, and supportive care measures. Monkeypox manifests with symptoms including fever, rash, and lymphadenopathy, with severe cases more common in immunocompromised individuals. Antiviral therapies such as tecovirimat and (...)
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  10. Evaluation of self-medication with antibiotics in Libyan community.Wafa Alsadiq Abdulsalam Meerah & Fathi M. Sherif - 2023 - Mediterranean Journal of Pharmacy and Pharmceutical Sciences 3 (1):77-81.
    Self-medication of antibiotics is an irrational use of drugs, contributing to microbial resistance, increasing healthcare costs and higher mortality and morbidity. This study aimed to assess self-medication with antibiotics without a medical prescription in the community of Libya. This is a cross-sectional study conducted from June to December 2022 and the total number of participants was 200. The design of the study and sample size were modified according to the proficiency of pharmacists and the medical and non-medical population of Libya. (...)
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  11. Antibiotics and Animal Agriculture: The need for global collective action.Jonny Anomaly - 2018 - In Michael Selgelid (ed.), Ethics and Antimicrobial Resistance. Oxford University Press. pp. 297-308.
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  12. Ethics, Antibiotics, and Public Policy.Jonny Anomaly - 2017 - Georgetown Journal of Law and Public Policy 15 (2).
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  13. Impartiality and infectious disease: Prioritizing individuals versus the collective in antibiotic prescription.Bernadine Dao, Thomas Douglas, Alberto Giubilini, Julian Savulescu, Michael Selgelid & Nadira S. Faber - 2019 - AJOB Empirical Bioethics 10 (1):63-69.
    Antimicrobial resistance (AMR) is a global public health disaster driven largely by antibiotic use in human health care. Doctors considering whether to prescribe antibiotics face an ethical conflict between upholding individual patient health and advancing public health aims. Existing literature mainly examines whether patients awaiting consultations desire or expect to receive antibiotic prescriptions, but does not report views of the wider public regarding conditions under which doctors should prescribe antibiotics. It also does not explore the ethical significance of (...)
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  14. Agents Isolated from Vaginal Cultures in the Reproductive Period and Their Antibiotic Sensitivities (Vaginal Culture and Antibiotic Sensitivitie).Kemal Dinç & Sümeyye Akyüz - 2023 - European Journal of Therapeutics 29 (1):55-59.
    Introduction: In our study, we aimed to examine the strains isolated from vaginal swab samples sent to our laboratory from various clinics with a pre-diagnosis of vulvovaginitis and antibiotic resistance rates, retrospectively.
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  15. Harm to Others: The social cost of antibiotics in agriculture.Jonny Anomaly - 2009 - Journal of Agricultural and Environmental Ethics 22 (5):423-435.
    See "What's Wrong with Factory Farming?" (2015) for an updated treatment of these issues.
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  16. Towards an Ontological Representation of Resistance: The Case of MRSA.Albert Goldfain, Barry Smith & Lindsay G. Cowell - 2011 - Journal of Biomedical Informatics 44 (1):35-41.
    This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. The treatments of resistance terms in various existing ontologies are examined and found to be either overly narrow, internally inconsistent, or otherwise problematic. We propose a more coherent characterization of resistance in terms of what we shall call blocking dispositions, which are collections of mutually coordinated dispositions which are of such a sort that they cannot undergo simultaneous realization within a single (...)
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  17. Intellectual Property and the Freedom Needed to Solve the Crisis of Resistant Infections.Gregory Salmieri - 2018 - George Mason Law Review 26 (1):215-229.
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  18. The case of psoriatic arthritis developed periorbital infection following adalimumab therapy.Tuba Tülay Koca & Gülbahar Saraç - 2014 - European Journal of Therapeutics 20 (4):323-327.
    Psoriatic arthritis is a chronic, systemic inflammatory disorder. It has been classified in spondyloarthropathies group which shares clinical, radiologic, serologic features, familial and genetic relationship. Up to 5-30% of patients with psoriasis may go on to develop psoriatic arthritis, usually within 5-10 years. Adalimumab (ADA) is the first human monoclonal antibody against TNF-α. ADA is a biologic agent effective in both skin lesions and joint signs. Anti-TNF agents are powerful immunmodulating drugs with potentially side effects. Our case is 38 years (...)
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  19. Unconscious mental factors in hiv infection.Peter Todd - 2008 - Mind and Matter 6 (2):193-206.
    Multiple drug resistant strains of HIV and continuing difficulties with vaccine development highlight the importance of psychologi- cal interventions which aim to in uence the psychosocial and emo- tional factors empirically demonstrated to be significant predictors of immunity, illness progression and AIDS mortality in seropositive persons. Such data have profound implications for psychological interventions designed to modify psychosocial factors predictive of enhanced risk of exposure to HIV as well as the neuroendocrine and immune mechanisms mediating the impact of such factors (...)
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  20. Efficacy of Colistin Therapy in Patients with Hematological Malignancies: What if There is Colistin Resistance?Zeynep Ture, Gamze Kalın Unüvar, Hüseyin Nadir Kahveci, Muzaffer Keklik & Ayşegül Ulu Kilic - 2023 - European Journal of Therapeutics 29 (1):17-22.
    Objective: The objective of this study was to evaluate the clinical efficacy and appropriateness of colistin therapy in patients with hematological malignancies. -/- Methods: Age, gender, type of hematologic malignancy, and potential carbapenem-resistant microorganism risk factors were all noted in this retrospective study. In empirical and agent-specific treatment groups, differences in demographic features, risk factors, treatment responses, and side effects were compared. -/- Results: Sixty-three patients were included, 54% were male, and the median age was 49. In the last three (...)
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  21. Addressing the Burden of Antimicrobial Resistance in Vietnamese Hospitals.Dat Vu Quoc - 2020 - Dissertation, The Open University
    Hospital acquired infections (HAIs), especially ventilator associated respiratory infection (VARI) cause significant morbidity and mortality, and disproportionally so in low and middle-income countries (LMICs), including Vietnam, where infection control in hospitals is often neglected. The management of HAIs in these settings is challenging because of the high proportions of antimicrobial drug resistance and limitations of laboratory diagnostics, financial and human resources in terms of knowledge and skills for antimicrobial stewardship and infection prevention and control.
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  22. Synergistic Approach of Graphene Oxide-Silver-Titanium Nanocomposite Film in Oral and Dental Studies: A New Paradigm of Infection Control in Dentistry.Siddhartha Dan, Sushil Kumar Upadhyay, Mohit Pant & Shaloo - 2021 - Biointerface Research in Applied Chemistry 11 (2):9680-9703.
    Nanoparticles have been used in numerous fields, various branches of science and engineering. These were used as a modification and to enhance the activity such as dentistry and oral investigation. The current survey uncovers that graphene oxide has been used to set up a variety of functionalized nanoparticles and progressed nanocomposites carriers. Graphene oxide shows potential in a variety of research examinations, for instance, tooth bleaching, antimicrobial activity, tooth erosion, teeth implants, toothaches, drug delivery at a specific site. All these (...)
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  23. Compensation for Cures: Paying People to Participate in Challenge Studies.Jonathan Anomaly & Julian Savulescu - 2019 - Bioethics 33 (7):792-797.
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  24. Collective Action and Individual Choice.Jonny Anomaly - 2013 - Journal of Medical Ethics 39 (4):752-756.
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  25. What's Wrong with Factory Farming?Jonny Anomaly - 2015 - Public Health Ethics 8 (3):246-254.
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  26. Bio-ethics and one health: a case study approach to building reflexive governance.Antoine Boudreau LeBlanc, Bryn Williams-Jones & Cécile Aenishaenslin - 2022 - Frontiers in Public Health 10 (648593).
    Surveillance programs supporting the management of One Health issues such as antibiotic resistance are complex systems in themselves. Designing ethical surveillance systems is thus a complex task (retroactive and iterative), yet one that is also complicated to implement and evaluate (e.g., sharing, collaboration, and governance). The governance of health surveillance requires attention to ethical concerns about data and knowledge (e.g., performance, trust, accountability, and transparency) and empowerment ethics, also referred to as a form of responsible self-governance. Ethics in reflexive (...)
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  27. Intensive Animal Agriculture and Human Health.Jonathan Anomaly - 2019 - In Bob Fischer (ed.), Routledge Handbook of Animal Ethics. New York: Routledge.
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  28. How Universities Can Best Respond to the Climate Crisis and Other Global Problems.Nicholas Maxwell - 2021 - Philosophies 1 (1):1.
    The world is in a state of crisis. Global problems that threaten our future include: the climate crisis; the destruction of natural habitats, catastrophic loss of wild life, and mass extinction of species; lethal modern war; the spread of modern armaments; the menace of nuclear weapons; pollution of earth, sea and air; rapid rise in the human population; increasing antibiotic resistance; the degradation of democratic politics, brought about in part by the internet. It is not just that universities around (...)
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  29. The World Crisis - And What To Do About It: A Revolution for Thought and Action.Nicholas Maxwell - 2021 - New Jersey: World Scientific.
    Two great problems of learning confront humanity: learning about the universe, and about ourselves and other living things as a part of the universe; and learning how to create a good, civilized, enlightened, wise world. We have solved the first great problem of learning – we did that when we created modern science and technology in the 17th century. But we have not yet solved the second one. That combination of solving the first problem, failing to solve the second one, (...)
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  30.  79
    A review on pneumonia in children: Clear insights.Iftear Kazim Rafi - 2024 - Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 4 (4):48-57.
    In developing nations, pneumonia is the leading cause of death for young children; however, mortality can be effectively decreased with early diagnosis and care. The objectives of the review are to evaluate the significance of clinical signs and symptoms in diagnosing pneumonia, and treatment in children under the age of five, as well as to examine the precision of WHO criteria in diagnosing clinical pneumonia in general people. According to the World Health Organization's definition and the Integrated Management of Childhood (...)
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  31.  19
    The Consequences of Human Overpopulation: Nature’s Automatic Balancing Mechanism.Angelito Malicse - manuscript
    The Consequences of Human Overpopulation: Nature’s Automatic Balancing Mechanism -/- Introduction -/- Throughout history, civilizations have risen and fallen due to their ability—or failure—to manage resources and population growth. In today’s world, human overpopulation has reached an unprecedented scale, straining ecosystems, depleting resources, and accelerating climate change. If population growth remains unchecked, nature will impose its own form of balance through disease, war, famine, and environmental collapse. This essay explores how overpopulation mirrors invasive species behavior and how nature’s corrective mechanisms (...)
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  32. Advancements in microbial-mediated radioactive waste bioremediation: A review.Chuck Chuan Ng - 2024 - Journal of Environmental Radioactivity 280 (December 2024):107530.
    The global production of radioactive wastes is expected to increase in the coming years as more countries have resorted to adopting nuclear power to decrease their reliance on fossil-fuel-generated energy. Discoveries of remediation methods that can remove radionuclides from radioactive wastes, including those discharged to the environment, are therefore vital to reduce risks-upon-exposure radionuclides posed to humans and wildlife. Among various remediation approaches available, microbe-mediated radionuclide remediation have limited reviews regarding their advances. This review provides an overview of the sources (...)
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  33. Historical and epistemological perspectives on what Lateral Gene Transfer mechanisms contribute to our understanding of evolution.Nathalie Gontier - 2015 - In Reticulate Evolution: Symbiogenesis, Lateral Gene Transfer, Hybridization and Infectious heredity. Springer. pp. 121-178.
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  34. Antimicrobial Footprints, Fairness, and Collective Harm.Anne Schwenkenbecher - 2020 - In Euzebiusz Jamrozik & Michael Selgelid (eds.), Ethics and Drug Resistance: Collective Responsibility for Global Public Health. Springer. pp. 379-389.
    This chapter explores the question of whether or not individual agents are under a moral obligation to reduce their ‘antimicrobial footprint’. An agent’s antimicrobial footprint measures the extent to which her actions are causally linked to the use of antibiotics. As such, it is not necessarily a measure of her contribution to antimicrobial resistance. Talking about people’s antimicrobial footprint in a way we talk about our carbon footprint may be helpful for drawing attention to the global effects of individual behaviour (...)
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  35. Utilization of Injectable Drugs for Communicable and Non-communicable Diseases in Primary Healthcare: A Retrospective Study in Turkey.Selcan Tülü Çolak, Caner Vızdıklar, Volkan Aydın, Başak Dönertaş Ayaz, Ali Alkan & Ahmet Akıcı - 2023 - European Journal of Therapeutics 29 (1):23-31.
    Objective: Primary care, which is often the first level of contact for patients with various communicable diseases (CDs) and noncommunicable diseases (NCDs), might exhibit patterns of injectable drug utilization different from hospitals. We aimed to examine injection prescribing to adults with CD or NCD in primary care. -/- Methods: In this retrospective study, single-diagnosis injectable drug-containing prescription data from Family Medicine Information System comprising 32 provinces of Turkey were analysed. The prescriptions were grouped by diagnosis as “CD” (n=3848) and “NCD” (...)
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  36. Placebo Use in the United Kingdom: Results from a National Survey of Primary Care Practitioners.Jeremy Howick - 2013 - PLoS 8 (3).
    Objectives -/- Surveys in various countries suggest 17% to 80% of doctors prescribe ‘placebos’ in routine practice, but prevalence of placebo use in UK primary care is unknown. Methods -/- We administered a web-based questionnaire to a representative sample of UK general practitioners. Following surveys conducted in other countries we divided placebos into ‘pure’ and ‘impure’. ‘Impure’ placebos are interventions with clear efficacy for certain conditions but are prescribed for ailments where their efficacy is unknown, such as antibiotics for suspected (...)
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  37. Clonal complexes in biomedical ontologies.Albert Goldfain, Lindsay Cowell & Barry Smith - 2009 - In Barry Smith (ed.), ICBO 2009: Proceedings of the First International Conference on Biomedical Ontology. Buffalo: NCOR. pp. 168.
    An accurate classification of bacteria is essential for the proper identification of patient infections and subsequent treatment decisions. Multi-Locus Sequence Typing (MLST) is a genetic technique for bacterial classification. MLST classifications are used to cluster bacteria into clonal complexes. Importantly, clonal complexes can serve as a biological species concept for bacteria, facilitating an otherwise difficult taxonomic classification. In this paper, we argue for the inclusion of terms relating to clonal complexes in biomedical ontologies.
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  38. Fisiologia e Patologias do Puerpério na Reprodução de Bovinos.Emanuel Isaque Cordeiro da Silva & Emanuel Isaque da Silva - manuscript
    PUERPÉRIO EM BOVINOS -/- INTRODUÇÃO -/- O puerpério é definido como o período entre o parto e a apresentação do primeiro estro fértil. Dois processos ocorrem durante o puerpério: a involução uterina e o início da atividade ovariana pós-parto. Em vacas leiteiras, os cuidados médicos pós-parto são essenciais nos programas de manejo, uma vez que as patologias uterinas são diagnosticadas e tratadas nesse período para que a vaca esteja em ótimas condições para ser inseminada, uma vez terminado o período de (...)
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  39. Effect of Trigona Honey to mRNA Expression of Interleukin-6 on Salmonella Typhi Induced of BALB/c Mice.Yuliana Syam, Rosdiana Natsir, Sutji Pratiwi Rahardjo, Andi Nilawati Usman, Ressy Dwiyanti & Mochammad Hatta - 2016 - American Journal of Microbiological Research 4 (3):77-80.
    Weak inflammatory response after Salmonella infection can cause persistent infection and facilitate the long survival of pathogens. Honey can induce key immunomodulators such as TNF-α, interleukin-6 (IL-6) and IL-1, that it can be used in the treatment of bacterial infectious diseases caused by Salmonella typhi. The purpose of this study is to determine the effect of honey on the mRNA expression of IL-6 in Salmonella enterica Typhi induced of BABL/c mice. The study used experimental pretest-posttest control design. Honey treatment (...)
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  40. Evolutionism: Logic, Language and Thought.Alexandru Anghelescu - 2016 - Procedia Environmental Sciences 2016 (32):184 – 189.
    Do other earthly forms of life evolved to the level of intelligent life? Cancer and resistance to antibiotics obliged to ask this question. Signs of intelligence are found at its simplest levels. We try to see if logic is used at these levels. Peter of Spain’s suppositio materialis is applied to the chemical signals of cells. Dynamic Logic is used to understand these chemical communications. <System of communications> is used, instead of “language”. The development of life appears as the development (...)
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  41. Considerações legais e forenses do aborto infeccioso bovino na “Saúde Única”: Revisão (18th edition).Jackson Barros Do Amaral, Vinícius José Moreira Nogueira & Wendell da Luz Silva (eds.) - 2024 - Londrina: Pubvet.
    In Brazil, the social demand for veterinary expertise is growing. However, there is still a shortage of professionals trained in this area to apply specific knowledge to each case. Studies and research into forensic veterinary medicine are necessary for veterinary experts to assist in investigations and legal proceedings. Veterinary medicine has subjects on its curriculum that cover the knowledge needed to apply in the fields of animal health, public health and the environment. The interaction between human and veterinary medicine, as (...)
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  42. Genomic Stress Responses Drive Lymphocyte Evolvability: An Ancient and Ubiquitous Mechanism.Bartlomiej Swiatczak - 2020 - Bioessays 42 (10):2000032.
    Somatic diversification of antigen receptor genes depends on the activity of enzymes whose homologs participate in a mutagenic DNA repair in unicellular species. Indeed, by engaging error-prone polymerases, gap filling molecules and altered mismatch repair pathways, lymphocytes utilize conserved components of genomic stress response systems, which can already be found in bacteria and archaea. These ancient systems of mutagenesis and repair act to increase phenotypic diversity of microbial cell populations and operate to enhance their ability to produce fit variants during (...)
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  43. The Ethics of Human Challenge Trials Using Emerging SARS-CoV-2 Virus Variants.Abie Rohrig & Nir Eyal - manuscript
    The world’s first COVID-19 human challenge trial using the D614G strain of SARS-CoV-2 is underway in the United Kingdom. The Wellcome Trust is funding challenge stock preparation of the Beta variant (B.1.351) for a follow-up human challenge trial, and researchers at Imperial College London are considering conducting that trial. However, little has been written thus far about the ethical justifiability of human challenge trials with SARS-CoV-2 variants of concern. While vaccine resistance as such does not increase risks for volunteers in (...)
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  44. The evosystem: A centerpiece for evolutionary studies.François Papale, Fabrice Not, Éric Bapteste & Louis-Patrick Haraoui - 2024 - Bioessays 46 (4):2300169.
    In this paper, we redefine the target of evolutionary explanations by proposing the “evosystem” as an alternative to populations, lineages and species. Evosystems account for changes in the distribution of heritable variation within individual Darwinian populations (evolution by natural selection, drift, or constructive neutral evolution), but also for changes in the networks of interactions within or between Darwinian populations and changes in the abiotic environment (whether these changes are caused by the organic entities or not). The evosystem can thereby become (...)
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  45. Teleonomy as a problem of self-causation.Nathalie Gontier - forthcoming - Biological Journal of the Linnean Society 139:388–414.
    A theoretical framework is provided to explore teleonomy as a problem of self-causation, distinct from upward, downward and reticulate causation. Causality theories in biology are often formulated within hierarchy theories, where causation is conceptualized as running up or down the rungs of a ladder-like hierarchy or, more recently, as moving between multiple hierarchies. Research on the genealogy of cosmologies demonstrates that in addition to hierarchy theories, causality theories also depend upon ideas of time. This paper explores the roots and impact (...)
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  46. Introduction: Hate and Racial Ignorance.Noell Birondo - 2022 - In The Moral Psychology of Hate. Lanham and London: Rowman & Littlefield.
    Dietrich Bonhoeffer was executed in Flossenbürg concentration camp in Germany in 1945 for being an “upstander” in Rivka Weinberg’s sense. He was an anti-Nazi conspirator, and he and some of his fellow Christians (he was a Lutheran pastor) were hanged in connection with a failed attempt to assassinate Adolph Hitler. Bonhoeffer’s resistance to racist hatred stands in sharp contrast to what he calls “Christian radicalism,” a total withdrawal from or an attempt to “improve” upon God’s creation, something Bonhoeffer characterizes as (...)
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  47. Architecture and Deconstruction. The Case of Peter Eisenman and Bernard Tschumi.Cezary Wąs - 2015 - Dissertation, University of Wrocław
    Architecture and Deconstruction Case of Peter Eisenman and Bernard Tschumi -/- Introduction Towards deconstruction in architecture Intensive relations between philosophical deconstruction and architecture, which were present in the late 1980s and early 1990s, belong to the past and therefore may be described from a greater than before distance. Within these relations three basic variations can be distinguished: the first one, in which philosophy of deconstruction deals with architectural terms but does not interfere with real architecture, the second one, in which (...)
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  48. Divergent Processing of Cell Stress Signals as the Basis of Cancer Progression: Licensing NFκB on Chromatin.Spiros A. Vlahopoulos - 2024 - IJMS 25 (16):8621.
    Inflammation is activated by diverse triggers that induce the expression of cytokines and adhesion molecules, which permit a succession of molecules and cells to deliver stimuli and functions that help the immune system clear the primary cause of tissue damage, whether this is an infection, a tumor, or a trauma. During inflammation, short-term changes in the expression and secretion of strong mediators of inflammation occur, while long-term changes occur to specific groups of cells. Long-term changes include cellular transdifferentiation for some (...)
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  49.  23
    Creativity and Intelligence: Emergent Properties of the Brain as a Balancing Mechanism for Overpopulation, Natural Disasters, and Diseases.Angelito Malicse - manuscript
    Creativity and Intelligence: Emergent Properties of the Brain as a Balancing Mechanism for Overpopulation, Natural Disasters, and Diseases -/- The human brain is an extraordinary organ, capable of producing creativity and intelligence as emergent properties that allow humanity to address complex challenges. These traits are not merely tools for individual survival; they function as collective mechanisms to adapt to large-scale issues that threaten humanity’s balance with the environment. Overpopulation, natural disasters, and the prevalence of diseases and illnesses represent some of (...)
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  50. Genealogy of Far-Right Accelerationism.Kieran Aarons - 2023 - Pólemos 2023 (1):261-294.
    Drawing on Furio Jesi’s 1979 book "Cultura di destra" [Right Wing Culture], this article sketches a preliminary genealogy of fascist accelerationism, a distinct current of white supremacist militancy responsible for a considerable number of North American mass murder events over the span of four decades. After positioning Jesi’s theory of fascist violence within the broader methodological turn of his late period work, the article proceeds to outline three key features of right-wing thought: a language of wordless ideas, a funerary religion (...)
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