Philosophers of language are increasingly engaging with derogatory terms or slurs. Only few theorists take such language as a starting point for addressing puzzles in philosophy of language with little connection to our real-world problems. This paper aims to show that the political nature of derogatory language use calls for non-ideal theorising as we find it in the work of feminist and critical race scholars. Most contemporary theories of slurs, so I argue, fall short on some desiderata associated with a (...) non-ideal approach. They neglect crucial linguistic or political aspects of morally and politically significant meaning. I argue that a two-stage project is necessary to understand the perniciousness of slurs: accounting for the derogatory content of derogatory terms in general and, additionally, explaining the communicative function of slurs more specifically. I end by showing how inferentialism is well-suited to account for the content of derogatory terms whilst allowing for further explanations of the communicative functions of slurs. (shrink)

Mikhail Bakhtin aimed to invent a phenomenology of the self-experience and of the experience of the other in his early work. In order to realize such a phenomenology he combined different approaches he called idealism and materialism / naturalism. The first one he linked to Edmund Husserl, but did hardly name him directly concerning his phenomenology. Does this intersubjective phenomenology give a hint that Bakhtin used Husserlian ideas more than considered yet? Or did they both invent similar ideas independently from (...) each other? Both thinkers dealt with the issue of intersubjectivity. Husserl judged statements on other psycho-physical realities as metaphysics in the Logical Investigations II, but in his Ideas I he described the others as enhancing one’s experience through their “experiential surpluses”. In the same way Bakhtin described the unique perspective of the other as a mandatory and valuable part of the world of the act in his Philosophy of the Act and his investigations on Author and Hero. In order to understand the influence of Husserl’s phenomenology for Bakhtin’s early philosophy we need to take a look closer at those contentual parallels as well as some paraphrases yet unnoticed. This gives hint for the question if for Bakhtin Husserl was more than just a name dropped. In this article I reconstructed the relations between both thinkers and answered the question if the dating of Bakhtin’s early work until 1928 has to be re-considered. (shrink)

There are different narratives on mathematics as part of our world, some of which are more appropriate than others. Such narratives might be of the form ‘Mathematics is useful’, ‘Mathematics is beautiful’, or ‘Mathematicians aim at theorem-credit’. These narratives play a crucial role in mathematics education and in society as they are influencing people’s willingness to engage with the subject or the way they interpret mathematical results in relation to real-world questions; the latter yielding important normative considerations. Our strategy is (...) to frame current narratives of mathematics from a virtue-theoretic perspective. We identify the practice of mathematizing, put forward by Freudenthal’s ‘Realistic mathematics education’, as virtuous and use it to evaluate different narratives. We show that this can help to render the narratives more adequately, and to provide implications for societal organization. (shrink)

While feminist philosophy has had much to say on the topic of reason, little has been done to develop a specifically feminist account of the concept. I argue for a virtue account of mind grounded in contemporary approaches to rationality. The evolutionary stance adopted within most contemporary theories of mind implicitly entails a rejection of central elements of Cartesianism. As a result, many accounts of rationality are anti-modern is precisely the sorts of ways that feminists demand. I maintain that a (...) virtue account of rationality can provide a satisfactory answer to Benhabib’s question in Situating of the Self: what concept of reason are we willing to defend? (shrink)

In arguing against the likelihood of consciousness in non-human animals, Descartes advances a slippery slope argument that if thought were attributed to any one animal, it would have to be attributed to all, which is absurd. This paper examines the foundations of Thomas Willis’ comparative neuroanatomy against the background of Descartes’ slippery slope argument against animal consciousness. Inspired by Gassendi’s ideas about the corporeal soul, Thomas Willis distinguished between neural circuitry responsible for reflex behaviour and that responsible for cognitively or (...) consciously mediated behaviour. This afforded Willis a non-arbitrary basis for distinguishing between animals with thought and consciousness and those without, a methodology which retains currency for neuroscience today. (shrink)

This paper analyses the hidden use of new axioms in set-theoretic practice with a focus on large cardinal axioms and presents a general overview of set-theoretic practices using large cardinal axioms. The hidden use of a new axiom provides extrinsic reasons in support of this axiom via the idea of verifiable consequences, which is especially relevant for set-theoretic practitioners with an absolutist view. Besides that, the hidden use has pragmatic significance for further important sub-groups of the set-theoretic community---set-theoretic practitioners with (...) a pluralist view and set-theoretic practitioners who aim for ZFC-proofs. By describing this, the paper gives a more complete picture of new axioms in set-theoretic practice. These observations, for instance, show that set-theoretic practitioners interested in ZFC-proofs use tools that go beyond ZFC. The analysis is based on empirical data that was collected in an extensive interview study with set-theoretic practitioners. (shrink)

Beyond “A Lecture on Ethics,” Wittgenstein says little on the topic of ethics, despite professing a great respect for ethics. I argue that while Wittgenstein ceases to speak of ethics, his account fits equally within his Tractarian and post-Tractarian writing. On both accounts of language, ethics remains nonsense, but it is not insignificant nonsense. However, because Wittgenstein holds ethics to concern absolute values that are in principle inexpressible, his anti-theoretical conception of ethics fails to offer guidance in how one ought (...) to live. That is, ethics ultimately cannot be show unless it can, in some sense, be said. (shrink)

Why are some people capable of sympathizing with and/or committing acts of political violence, such as attacks aimed at innocent targets? Attempts to construct terrorist profiles based on individual and situational factors, such as clinical, psychological, ethnic, and socio-demographic variables, have largely failed. Although individual and situational factors must be at work, it is clear that they alone cannot explain how certain individuals are radicalized. In this paper, we propose that a comprehensive understanding of radicalization and of how it may (...) lead to political violence requires the integration of information across multiple levels of analysis and interdisciplinary perspectives from evolutionary theory, social, personality and cognitive psychology, political science and neuroscience. Characterization of the structural-functional relationships between neural mechanisms and the cognitive and affective psychological processes that underpin group dynamics, interpersonal processes, values and narratives, as well as micro-sociological processes may reveal latent drivers of radicalization and explain why some people turn to extreme political violence. These drivers may not be observable within a single individual level of scientific enquiry. The integrative, multilevel approach that characterizes social neuroscience has the potential to provide theoretical and empirical clarity regarding the antecedents of radicalization and support for extreme violence. (shrink)

Feminist philosophy is highly critical of Cartesian, and more broadly Enlightenment, conceptions of rationality. However, feminist philosophers typically fail to address contemporary theories of rationality and to consider how more current thoeories address feminist concerns. I argue that, contrary to their protestations, feminists are “obsessing over an outdated conception of reason” and that even the most suspect of “malestream” philosophers express an understanding of rationality that is closer to feminist concerns than Cartesian ones. I begin by briefly examining key features (...) of Cartesian rationality and discuss how these features are largely rejected by contemporary philosophy and cognitve science. I then discuss how the philosophical accounts of Robert Nozick and Robert Audi refelect this rejection of Cartesian rationality. Finally, I discuss how the views of Nozick and Audi are in line with many feminist concerns, and I argue that feminists need to take seriously some theory of rationality. (shrink)

This volume includes nineteen articles by scholars from Asia, North America, and Europe on Chinese thinkers from the eleventh to the eighteenth centuries. Included here are intellectual biographies of literati such as Zhou Dunyi, the Cheng brothers, Zhu Xi, Zhang Shi, Hu Hong, Wang Yangming, and Dai Zhen. Essays are arranged chronologically, and most begin with a biographical sketch of their subject. They provide variety rather than uniformity of approach, but all in all these essays are remarkably rich and offer (...) much new material on both familiar and lesser-known thinkers. (shrink)

This article examines the complaint that arbitrary algorithmic decisions wrong those whom they affect. It makes three contributions. First, it provides an analysis of what arbitrariness means in this context. Second, it argues that arbitrariness is not of moral concern except when special circumstances apply. However, when the same algorithm or different algorithms based on the same data are used in multiple contexts, a person may be arbitrarily excluded from a broad range of opportunities. The third contribution is to explain (...) why this systemic exclusion is of moral concern and to offer a solution to address it. (shrink)

The ji 己self is a site, storehouse, or depot of individuated allotment associated with the possession of things and qualities: wholesome and unwholesome desires (yu 欲) and aversions, emotions such as anxiety, and positive values such as humaneness and reverence. Each person's allotment is unique, and its "contents" are collected, measured, reflected on, and then distributed to others. The Analects, Mencius, Xunzi, Daodejing, and Zhuangzi each have their own vision for negotiating the space between self and other. Works as seemingly (...) dissimilar as the Analects and Daodejing both agree that positive qualities located within the self should be shared with others, and that the self can be optimized rather than maximized through sharing, emptying, or clearing. Sommer compares the ji self with other terms for body and person current in classical times. This self is strongly individuated, but it exists primarily in relation to other human beings (ren 人 ). These "others" are almost never one's own kind and are usually people who fall outside one's ascribed familial and social relationships. Negotiations between self and other often reflect apprehension regarding degrees of distance, intimacy, worth, recognition, or understanding (zhi 知) between people. (shrink)

Although feminists have spilled a great deal of ink criticizing Enlightenment conceptions of rationality, the time has come to consider constructing a positive account. Recent attempts to construct an account of rationality as a virtue concept reflect many feminist complaints concerning Enlightenment rationality, and, thus, I maintain that feminism should take seriously such a conception. Virtue rationality offers a more diverse account of rationality without sacrificing the fundamental normativity of the concept. Furthermore, the narrower concept of reasonableness, promises to provide (...) a ground for distinguishing among better and worse epistemic perspectives, which is a task critical to the success of the feminist project. (shrink)

ABSTRACT: Virtue, the centerpiece of ancient ethics, has come under attack by virtue skeptics impressed by results of psychology experiments including Milgram's obedience studies. The virtue skeptic argues that experimental findings suggest that character structures are so fragile vis-å-vis situational factors as to be explanatorily superfluous: virtues and robust character traits are a myth, and should be replaced by situation-specific "narrow dispositions" (Gilbert Harman) or "local traits" (John Doris). This paper argues that the virtue skeptics' sweeping claims are ill-founded. First, (...) blending Aristotelian and contemporary insights about virtue, I reach a decision about a reasonable, non-straw definition of "virtue" and of "character trait." Next, I argue that explanations give by Lee Ross and Richard Nisbett for the Milgram findings covertly invoke character traits. Reflection reveals that more robust, cross-situationally consistent traits are needed for explanation of subject behavior, and that it is reasonable to suppose that such traits were in place. (shrink)

In this paper, I argue that poet M. Nourbese Philip's Zong! allows us to radically rethink the possibility of historical restitution and recovery. The formal ideas in Zong!, I argue, imply a metaphysical and ontological revolution in the way memory and mnesic traces are to be conceived. The evidentiary status of the voices and narratives that Zong! retrieves cannot be certified by historical-epistemological conceptions of evidence but rather find their warrant in alternative, ontological (or hauntological) registers.

In On Touching, Derrida commends philosopher Jean-Luc Nancy for ‘taking into account [the] plasticity and technicity “at the heart” of the “body proper.”’ Specifying the meaning of this plasticity and technicity, Derrida writes, the"[s]upplementarity of technical prosthetics originarily spaces out, defers, or expropriates all originary properness: there is no “the” sense of touch, there is no “originary” or essentially originary touching before it." What is ‘proper’ or ‘original’ to the body, it seems, is not any set of properties or capacities (...) – including sensorial or perceptual powers – but rather the ‘plastic and substitutive structure of prosthetics’, the very possibility of the body’s ‘technical’ supplementation. (shrink)

This paper focusses on the relationship among structural adjustment policies and practices, the business activities of transnational corporations and what Robert Reich has called the coming irrelevance of corporate nationality. The argument presented is that the force of these combined factors makes environmental sustainability impossible.

An overview and comparison of the major teaching philosophies is discussed to determine their applications in the field of education. In the end, it is important to reflect on how our practices align with our philosophies.

Penelope Maddy’s Second Philosophy is one of the most well-known ap- proaches in recent philosophy of mathematics. She applies her second-philosophical method to analyze mathematical methodology by reconstructing historical cases in a setting of means-ends relations. However, outside of Maddy’s own work, this kind of methodological analysis has not yet been extensively used and analyzed. In the present work, we will make a first step in this direction. We develop a general framework that allows us to clarify the procedure and (...) aims of the Second Philosopher’s investigation into set-theoretic methodology; pro- vides a platform to analyze the Second Philosopher’s methods themselves; and can be applied to further questions in the philosophy of set theory. (shrink)

The ethical issues raised by cybersecurity practices and technologies are of critical importance. However, there is disagreement about what is the best ethical framework for understanding those issues. In this paper we seek to address this shortcoming through the introduction of a principlist ethical framework for cybersecurity that builds on existing work in adjacent fields of applied ethics, bioethics, and AI ethics. By redeploying the AI4People framework, we develop a domain-relevant specification of five ethical principles in cybersecurity: beneficence, non-maleficence, autonomy, (...) justice, and explicability. We then illustrate the advantages of this principlist framework by examining the ethical issues raised by four common cybersecurity contexts: penetration testing, distributed denial of service attacks (DDoS), ransomware, and system administration. These case analyses demonstrate the utility of this principlist framework as a basis for understanding cybersecurity ethics and for cultivating the ethical expertise and ethical sensitivity of cybersecurity professionals and other stakeholders. (shrink)

Using artificial intelligence (AI) to make decisions in human resource management (HRM) raises questions of how fair employees perceive these decisions to be and whether they experience respectful treatment (i.e., interactional justice). In this experimental survey study with open-ended qualitative questions, we examine decision making in six HRM functions and manipulate the decision maker (AI or human) and decision valence (positive or negative) to determine their impact on individuals’ experiences of interactional justice, trust, dehumanization, and perceptions of decision-maker role appropriate- (...) ness. In terms of decision makers, the use of human decision makers over AIs generally resulted in better perceptions of respectful treatment. In terms of decision valence, people experiencing positive over negative decisions generally resulted in better perceptions of respectful treatment. In instances where these cases conflict, on some indicators people preferred positive AI decisions over negative human decisions. Qualitative responses show how people identify justice concerns with both AI and human decision making. We outline implications for theory, practice, and future research. (shrink)

Health service consumers' satisfaction with the services they receive has been a challenge over the past decade, and this has been attributed to many factors that diverse scholars have investigated using different variables. In this study, the attitude and ethical behaviours of healthcare providers as antidotes to health service consumers' satisfaction in the Primary Health Centre at Mgbuoshimini, Port Harcourt, Nigeria, were investigated. A cross-sectional descriptive research design was used to select participants from pregnant women, nursing mothers, couples for family (...) planning, and sick patients. The data were analysed using descriptive statistical tools. The results of the grand total response values were 400 (100%) and strongly agree had 190 (47.5%), agree had 160 (40%), 390 (100%) and strongly agree had 260 (66.7%), agree had 100 (25.6%), and strongly disagree had 13 (3.3%). The overall results were strongly agreed (66.7%) and agreed (25.6%); these connote that the attitudes and ethical behaviours of the healthcare providers towards healthcare service consumers in the primary healthcare facility were poor and that healthcare providers do not execute good ethical behaviour towards health service consumers in the facility, leading to low levels of health resource consumption, low patronage image promotion, and consumers' loss of confidence in the service provider. Therefore, the government should put mechanisms in place to ensure a positive attitude and favourable ethical behaviour among healthcare providers, and individual healthcare providers should also acquire soft skills to improve their attitude and ethical behaviour. (shrink)

The COVID-19 pandemic demonstrated the benefits of international data sharing. Data sharing enabled the health care policy makers to make decisions based on real-time data, it enabled the tracking of the virus, and importantly it enabled the development of vaccines that were crucial to mitigating the impact of the virus. This data sharing is not the norm as data sharing needs to navigate complex ethical and legal rules, and in particular, the fragmented application of the General Data Protection Regulation (GDPR). (...) The introduction of the draft regulation for a European Health Data Space (EHDS) in May 2022 seeks to address some of these legal issues. If passed, it will create an obligation to share electronic health data for certain secondary purposes. While there is a clear need to address the legal complexities involved with data sharing, it is critical that any proposed reforms are in line with ethical principles and the expectations of the data subjects. In this paper we offer a critique of the EHDS and offer some recommendations for this evolving regulatory space. (shrink)

Forms of Artificial Intelligence (AI) are already being deployed into clinical settings and research into its future healthcare uses is accelerating. Despite this trajectory, more research is needed regarding the impacts on patients of increasing AI decision making. In particular, the impersonal nature of AI means that its deployment in highly sensitive contexts-of-use, such as in healthcare, raises issues associated with patients’ perceptions of (un) dignified treatment. We explore this issue through an experimental vignette study comparing individuals’ perceptions of being (...) treated in a dignified and respectful way in various healthcare decision contexts. Participants were subject to a 2 (human or AI decision maker) x 2 (positive or negative decision outcome) x 2 (diagnostic or resource allocation healthcare scenario) factorial design. We found evidence of a “human bias” (i.e., a preference for human over AI decision makers) and an “outcome bias” (i.e., a preference for positive over negative outcomes). However, we found that for perceptions of respectful and dignified interpersonal treatment, it matters more who makes the decisions in diagnostic cases and it matters more what the outcomes are for resource allocation cases. We also found that humans were consistently viewed as appropriate decision makers and AI was viewed as dehumanizing, and that participants perceived they were treated better when subject to diagnostic as opposed to resource allocation decisions. Thematic coding of open-ended text responses supported these results. We also outline the theoretical and practical implications of these findings. (shrink)

The objective of Working Group 4 of the COST Action NET4Age-Friendly is to examine existing policies, advocacy, and funding opportunities and to build up relations with policy makers and funding organisations. Also, to synthesize and improve existing knowledge and models to develop from effective business and evaluation models, as well as to guarantee quality and education, proper dissemination and ensure the future of the Action. The Working Group further aims to enable capacity building to improve interdisciplinary participation, to promote knowledge (...) exchange and to foster a cross-European interdisciplinary research capacity, to improve cooperation and co-creation with cross-sectors stakeholders and to introduce and educate students SHAFE implementation and sustainability. To enable the achievement of the objectives of Working Group 4, the Leader of the Working Group, the Chair and Vice-Chair, in close cooperation with the Science Communication Coordinator, developed a template to map the current state of SHAFE policies, funding opportunities and networking in the COST member countries of the Action. On invitation, the Working Group lead received contributions from 37 countries, in a total of 85 Action members. The contributions provide an overview of the diversity of SHAFE policies and opportunities in Europe and beyond. These were not edited or revised and are a result of the main areas of expertise and knowledge of the contributors; thus, gaps in areas or content are possible and these shall be further explored in the following works and reports of this WG. But this preliminary mapping is of huge importance to proceed with the WG activities. In the following chapters, an introduction on the need of SHAFE policies is presented, followed by a summary of the main approaches to be pursued for the next period of work. The deliverable finishes with the opportunities of capacity building, networking and funding that will be relevant to undertake within the frame of Working Group 4 and the total COST Action. The total of country contributions is presented in the annex of this deliverable. (shrink)

I. EXECUTIVE SUMMARY The MRCT Center Post-trial Responsibilities: Continued Access to an Investigational Medicine Framework outlines a case-based, principled, stakeholder approach to evaluate and guide ethical responsibilities to provide continued access to an investigational medicine at the conclusion of a patient’s participation in a clinical trial. The Post-trial Responsibilities (PTR) Framework includes this Guidance Document as well as the accompanying Toolkit. A 41-member international multi-stakeholder Workgroup convened by the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard University (...) (MRCT Center) developed this Guidance and Toolkit. Project Motivation A number of international organizations have discussed the responsibilities stakeholders have to provide continued access to investigational medicines. The World Medical Association, for example, addressed post-trial access to medicines in Paragraph 34 of the Declaration of Helsinki (WMA, 2013): “In advance of a clinical trial, sponsors, researchers and host country governments should make provisions for post-trial access for all participants who still need an intervention identified as beneficial in the trial. This information must also be disclosed to participants during the informed consent process.” This paragraph and other international guidance documents converge on several consensus points: • Post-trial access (hereafter referred to as “continued access” in this Framework [for terminology clarification – see definitions]) is the responsibility of sponsors, researchers, and host country governments; • The plan for continued access should be determined before the trial begins, and before any individual gives their informed consent; • The protocol should delineate continued access plans; and • The plan should be transparent to potential participants and explained during the informed consent process. -/- However, there is no guidance on how to fulfill these responsibilities (i.e., linking specific responsibilities with specific stakeholders, conditions, and duration). To fill this gap, the MRCT Center convened a working group in September of 2014 to develop a framework to guide stakeholders with identified responsibilities. This resultant Framework sets forth applicable principles, approaches, recommendations and ethical rationales for PTR regarding continued access to investigational medicines for research participants. (shrink)

This paper reports on an ongoing ARC Discovery Project that is conducting design research into learning in collaborative virtual worlds (CVW).The paper will describe three design components of the project: (a) pedagogical design, (b)technical and graphics design, and (c) learning research design. The perspectives of each design team will be discussed and how the three teams worked together to produce the CVW. The development of productive failure learning activities for the CVW will be discussed and there will be an interactive (...) demonstration of the project's CVW. (shrink)

In summary, Hellman’s book is well worth reading. It is powerful, well-written, and interesting and explains much of the prominent case law on discrimination. Her theory, however, is false because her explanation of wrongful discrimination fails to track a wrong-making feature. Her theory does not focus on a right-infringement in or unfair treatment of the person whom is discriminated against. It also does not focus on an incorrect attitude in the person who discriminates. These intuitively seem to exhaust the reasons (...) that make an act wrong because it wrongs someone. Her account of wrongful discrimination fails to identify the correct wrong-making feature. (shrink)

Deborah Boyle's book is a splendid addition to the literature on the philosophy of Margaret Cavendish. It provides an overview of Cavendish's philosophical work, from her panpsychist materialism, through her views about human motivation and general political philosophy, to views about gender, health, and humans' relation to the rest of the natural world. Boyle emphasizes themes of order and regularity, but does not argue that there is a strong systematic connection between Cavendish's views. Indeed, she makes a point of (...) noting the different ways in which the themes of order and regularity work in different areas of Cavendish's philosophy.The early chapters consider Cavendish's natural philosophy.... (shrink)

What is the relationship between prophetic vision and vision in terms for a hoped-for future? How might vision for a church or person best be defined today?

It is facile and factually incorrect to represent suicide terrorists as simply seeking mass destruction, as demented or believing that they will be rewarded by "seventy-two virgins in paradise". In my book The Myth of the Closed Mind: Understanding How and Why People are Rational I felt it was important to deal with the issue of terrorism by consulting explanatory theories of human behaviour and the substantial research on the strategic pattern of terrorist incidents over the decades, led principally by (...) Professor Robert Pape of Chicago University. -/- To defeat your enemy, you must first understand him. Strangely, we must first grant that, though morally depraved, terrorists are rational: they concoct and execute detailed plans with definite strategic goals in mind. Only once we have granted the terrorist a rational mind can we, in the end, create peace. My argument is that while religion may have a small role in terrorism, it is principally politics, or the logic of territorial control, that is the key to understanding the threat we face. -/- This extract from my book is principally about Al Qaeda, but a similar analysis applies to ISIS, the current greatest threat to our peace in the west. -/- The strategic goal of Al Qaeda was simply to repulse what they saw as foreign intervention. ISIS has the same goal, but in order to continue its growth as a state in the sense of a monopoly of coercion over a given geographical area. -/- ISIS, a rogue state that arose in ungoverned space created unintentionally by foreign intervention in Iraq, is now lashing out at foreign governments that have severely shrunk the territory ISIS occupies. Before October 2015, ISIS confined its terrorism to the goal of extending its territory in Iraq and Syria, and there were no significant ISIS-led or inspired suicide terrorist attacks outside Iraq and Syria. But now, as their territory collapses, they are attacking the countries that have strangled their control of territory in Iraq and Syria: the coalition of western governments – Britain, Belgium, Canada, France, Morocco, Turkey, Russia, the U.S.A. and others – exactly the countries that have recently seen an explosion of suicide terrorism. (shrink)

The central role of gestural language in Buddhism is widely acknowledged, as in the story of the Buddha pointing at the moon, the point being the student’s seeing beyond the finger to its gesture. Gesture’s role in dance is similarly central, as noted by scholars in the emerging interdisciplinary field of dance studies. Unsurprisingly, then, the intersection of these two fields is well-populated, including the formal gestures Buddhism inherited from classical Indian dance, and the masked dance of the Mani Rimdu (...) Festival. In this investigation, I will articulate a new Buddhist philosophy of gestural language, based on a new conception of emptiness that I locate in the work of contemporary U.S. choreographer Deborah Hay, as influenced by Nāgārjuna and Zen. And this, finally, suggests that contemporary Western philosophy should incorporate this compassion as a normative dimension to its own theorizing and practice. (shrink)

Purpose – The purpose of this paper is to assess the impact of smallholder supply chains on sustainable sourcing to answer the question how food and agribusiness multinationals can best include smallholders in their sourcing strategies and take social responsibility for large-scale sustainable and more equitable supply. A sustainable smallholder sourcing model with a list of critical success factors (CSFs) has been applied on two best-practise cases. In this model, business and corporate social responsibility perspectives are integrated. Design/methodology/approach – The (...) primary data of the value chain analyses of the two smallholder supply chains of a food and agribusiness multinational have been applied. Both cases were of a join research program commissioned by the multinational and a non-governmental organization using the same methods and research tools. Similarities, differences and interference between the cases have been determined and assessed in order to confirm, fine tune or adjust the CSFs. Findings – Both cases could be conceptualized through the smallholder sourcing model. Most CSFs could be found in both cases, but differences were also found, which led to fine tuning of some CSFs: building of a partnership and effective producers organization, providing farm financing and the use of cross-functional teams in smallholder supplier development programs. It was also concluded that the smallholder sourcing model is applicable in different geographical areas. Research limitations/implications – The findings of this study are based on just two cases. More best-practise cases are recommended in order to confirm or to adjust the developed sourcing model and the CSFs. Originality/value – This paper/research fills the need in sustainable supply chain management literature to study supply chains that comply with the triple bottom line concept, rather than supply chains that are just more “green.” Keywords Small- to medium-sized enterprises, Food products, Supply chain management, Developing countries, Business development, Food industry, Commodity markets Paper type Research pape. (shrink)

This provocation critiques the notion of long-term thinking and the claims of its proponents that it will help address failures in dominant conceptions of time, particularly in regard to environmental crises. Drawing on analyses of the Clock of the Long Now and Kim Stanley Robinson’s The Ministry for the Future, the article suggests that we be more wary of the concept’s use in what we might call chronowashing. Like the more familiar greenwashing, where environmental issues are hidden by claims to (...) be addressing the problem, the article explores how these examples of long-term thinking distract from extractivism, racism, and environmental injustice, making it harder to address the complexities involved. In particular, the article discusses examples where long-term thinking provides a veneer of environmental concern that actually disconnects from the work of building more equitable forms of relation. As a contrast, the article’s author asks: What is lost when we diagnose a problem as arising due to short-term thinking and propose long-term thinking as the solution? Against chronowashed environmental time, the author argues for more complex approaches that explicitly take into account the temporalities of inequality, political organization, ethical responsibilities and much else. The article engages with approaches to time that foreground the work needed to create time and move ethically within it, including Charles W. Mills’s white time and Kyle Powys Whyte’s kinship time. The author suggests that a stronger emphasis on the temporality of community, solidarity, and coalition—versus what James Hatley and Deborah Bird Rose have described as temporal narcissism—can better foreground the kinds of work that needs to be done, particularly by those with privilege. (shrink)

Recent studies have shown that recidivism scoring algorithms like COMPAS have significant racial bias: Black defendants are roughly twice as likely as white defendants to be mistakenly classified as medium- or high-risk. This has led some to call for abolishing COMPAS. But many others have argued that algorithms should instead be given access to a defendant's race, which, perhaps counterintuitively, is likely to improve outcomes. This approach can involve either establishing race-sensitive risk thresholds, or distinct racial ‘tracks’. Is there a (...) moral difference between these two approaches? We first consider Deborah Hellman's view that the use of distinct racial tracks (but not distinct thresholds) does not constitute disparate treatment since the effects on individuals are indirect and does not rely on a racial generalization. We argue that this is mistaken: the use of different racial tracks seems both to have direct effects on and to rely on a racial generalization. We then offer an alternative understanding of the distinction between these two approaches—namely, that the use of different cut points is to the counterfactual comparative disadvantage, ex ante, of all white defendants, while the use of different racial tracks can in principle be to the advantage of all groups, though some defendants in both groups will fare worse. Does this mean that the use of cut points is impermissible? Ultimately, we argue, while there are reasons to be skeptical of the use of distinct cut points, it is an open question whether these reasons suffice to make a difference to their moral permissibility. (shrink)

L’Amérique et le monde sont en train de s’effondrer à cause d’une croissance démographique excessive, la plupart pour le siècle dernier et maintenant tout cela en raison de la 3e population mondiale. La consommation de ressources et l’ajout d’un ou deux milliards de dollars de plus vers 2100 vont effondrer la civilisation industrielle et provoquer la famine, la maladie, la violence et la guerre à une échelle stupéfiante. Des milliards vont mourir et la guerre nucléaire est presque certaine. En Amérique, (...) cela est considérablement accéléré par l’immigration massive et la reproduction des immigrants, combinée avec des abus rendus possibles par la démocratie. La nature humaine dépravée transforme inexorablement le rêve de démocratie et de diversité en cauchemar de la criminalité et de la pauvreté. La cause profonde de l’effondrement est l’incapacité de notre psychologie innée à s’adapter au monde moderne, ce qui conduit les gens à traiter des personnes sans lien de parenté comme s’ils avaient des intérêts communs. Ceci, plus l’ignorance de la biologie de base et de la psychologie, conduit aux illusions d’ingénierie sociale des personnes partiellement instruites qui contrôlent les sociétés démocratiques. Peu de gens comprennent que si vous aidez une personne, vous faites du mal à quelqu’un d’autre, il n’y a pas de déjeuner gratuit et chaque article que quelqu’un consomme détruit la terre au-delà de la réparation. Par conséquent, les politiques sociales partout sont insoutenables et une à une toutes les sociétés sans contrôle strict sur l’égoïsme s’effondreront dans l’anarchie ou la dictature. Sans changements dramatiques et immédiats, il n’y a aucun espoir pour empêcher l’effondrement de l’Amérique, ou tout autre pays qui suit un système démocratique. D’où mon essai "Suicide by Democracy". Il est également maintenant clair que les sept sociopathes qui gouvernent la Chine gagnent la guerre mondiale 3, et donc mon essai final sur eux. La seule plus grande menace est l’intelligence artificielle que je commente brièvement. La clé de tout ce qui nous concerne est la biologie, et c’est l’oubli qui conduit des millions de personnes instruites intelligentes comme Obama, Chomsky, Clinton, le Parti démocrate et le pape à épouser des idéaux utopiques suicidaires suicidaires qui mènent inexorablement directement à l’enfer sur Terre. Comme W l’a fait remarquer, c’est ce qui est toujours sous nos yeux qui est le plus difficile à voir. Nous vivons dans le monde du système linguistique délibératif conscient 2, mais c’est inconscient, système réflexif automatique 1 qui règne. C’est la source de la cécité universelle décrite par L’illusion phénoménologique (TPI) de Searle, Blank Slate de Pinker et Tooby et le modèle standard de science sociale de Cosmides. Le premier groupe d’articles tente de donner un aperçu de la façon dont nous nous comportons qui est raisonnablement exempt d’illusions théoriques. Dans les trois groupes suivants, je commente trois des principales illusions empêchant un monde durable : la technologie, la religion et la politique (groupes coopératifs). Les gens croient que la société peut être sauvée par eux, donc je fournis quelques suggestions dans le reste du livre quant à pourquoi cela est peu probable par le biais de courts articles et des critiques de livres récents par des écrivains bien connus. Un autre section decrit l’illusion religieuse - qu’il ya un certain super pouvoir qui nous sauvera. La section suivante décrit les délires numériques, qui confondent les jeux linguistiques du système 2 avec les automatismes du système un, et ne peut donc pas distinguer les machines biologiques (c’est-à-dire les gens) d’autres types de machines (c.-à-d. les ordinateurs). D’autres illusions numériques sont que nous serons sauvés du mal pur (égoïsme) du système 1 par les ordinateurs /AI/robotique/nanotech/génie génétique créé par le système 2. Le directeur du no Free Lunch nous dit qu’il y aura des conséquences graves et peut-être fatales. La dernière section décrit The One Big Happy Family Delusion, c’est-à-dire que nous sommes sélectionnés pour la coopération avec tout le monde, et que les idéaux euphonieux de la démocratie, de la diversité et de l’égalité nous mèneront à l’utopie, si nous gérons les choses correctement (la possibilité de la politique). Encore une fois, le principe du non-déjeuner libre devrait nous avertir qu’il ne peut pas être vrai, et nous voyons à travers l’histoireet partout dans le monde contemporain, que sans contrôles stricts, l’égoïsme et la stupidité prennent le dessus et détruisent bientôt toute nation qui embrasse ces illusions. En outre, l’esprit singe écarte fortement l’avenir, et nous coopérons donc à la vente du patrimoine de notre descendant pour des conforts temporaires, exacerbant considérablement les problèmes. (shrink)

Je suis d'avis que la table de l'intentionnalité (rationalité, esprit, conscience, pensée, langage, personnalité, etc.) qui figure en bonne place ici décrit plus ou moins précisément, ou du moins sert d'heuristique pour, comment nous pensons et nous nous comportions, et donc il n'englobe pas simplement la philosophie et la psychologie, mais tout le reste (histoire, littérature, mathématiques, politique, etc.). Notez en particulier que l'intentionnalité et la rationalité que je (avec Searle, Wittgenstein et d'autres) le voir, comprend à la fois conscient (...) délibératif système linguistique 2 et inconscient automatisé système prélinguistique 1 actions ou réflexes. Je fournis une enquête critique de quelques-unes des principales conclusions de deux des plus éminents étudiants du comportement des temps modernes, Ludwig Wittgenstein et John Searle, sur la structure logique de l'intentionnalité (esprit, langue, comportement), en prenant comme point de départ La découverte fondamentale de Wittgenstein, à savoir que tous les problèmes véritablement « philosophiques » sont les mêmes, les confusions sur la façon d'utiliser la langue dans un contexte particulier, et donc toutes les solutions sont les mêmes— en regardant comment la langue peut être utilisée dans le contexte en cause afin que sa vérité (Conditions de satisfaction ou COS) sont claires. Le problème fondamental est que l'on peut dire n'importe quoi, mais on ne peut pas signifier (état clair COS pour) toute déclaration arbitraire et le sens n'est possible que dans un contexte très spécifique. J'analyse divers écrits par et à leur sujet du point de vue moderne des deux systèmes de pensée (popularisés comme «penser vite, penser lentement»), en utilisant une nouvelle table de l'intentionnalité et de nouvelles nomenclatures de systèmes doubles. Je montre que c'est un puissant heuristique pour décrire le comportement. Ainsi, tout comportement est intimement lié si l'on prend le point de vue correct. L'illusion phénoménologique (oubli de notre système automatisé 1) est universelle et s'étend non seulement à travers la philosophie, mais tout au long de la vie. Je suis sûr que Chomsky, Obama, Zuckerberg et le pape serait incrédule si on leur dit qu'ils souffrent du même problème que Hegel, Husserl et Heidegger, (ou qu'ils diffèrent seulement dans le degré de la drogue et les toxicomanes du sexe en étant motivés par la stimulation de leur cortices frontaux par la livraison de dopamine (et plus de 100 autres produits chimiques) via le tegmentum ventral et le noyau accumbens), mais c'est clairement vrai. Alors que les phénoménologues ne gaspillaient que beaucoup de temps, ils gaspillent la terre et l'avenir de leur descendant. (shrink)

In this paper I argue for a novel interpretation of Shepherd’s notion of selfhood. In distinction to Deborah Boyle’s interpretation, I contend that Shepherd differentiates between the mind and the self. The latter, for Shepherd, is an effect arising from causal interactions between mind and body – specifically those interactions that give rise to our present stream of consciousness, our memories, and that can unite these two. Thus, the body plays a constitutive role in the formation of the self. (...) The upshot of this interpretation is that it can dissolve the problem of individuating mind that Boyle identifies. Briefly, the problem consists in Shepherd seemingly individuating minds in terms of their associated bodies and bodies in terms of the minds they are united with. My interpretation, however, allows to see that Shepherd neither wants nor needs to individuate the mind in isolation of the body and to read the passages, in which the problem seems to arise, as being about what makes living beings individual – with mind and body both playing a crucial role in this context. (shrink)

According to a widely accepted constraint on the content of intentions, here called the exclusivity constraint, one cannot intend to perform another agent’s action, even if one might be able to intend that she performs it. For example, while one can intend that one’s guest leaves before midnight, one cannot intend to perform her act of leaving. However, Deborah Tollefsen’s (2005) account of joint activity requires participants to have intentions-in-action (in John Searle’s (1983) sense) that violate this constraint. I (...) argue that the exclusivity constraint should not be accepted as an unconditional constraint on the contents of intentions-in-action: one may intend to perform a basic action that belongs both to oneself and to another agent. Based on the phenomenology of tool use, I first argue that intentions-in-action of one’s basic actions may be technologically extended, meaning that their contents are not restricted to concern the agent’s bodily movements. In analogy with this, I then argue that the phenomenology of some skillful joint activities supports the idea that one’s basic intentions-in-action may be socially extended, in violation of the widely accepted exclusivity constraint. Tollefsen’s account is specifically constructed to account for the joint activities of infants and toddlers who lack the capacity to think of others as planning agents and grasp their plan-like intentions (a capacity required by Michael Bratman’s (1992, 1993, 2009a, b) influential account of joint activity). At the end of the paper, I raise some doubts regarding the extent to which infants and toddlers have socially extended intentions-in-action. (shrink)

The argument between Jacques Maritain and Charles de Koninck over the primacy of the common good is well known. Yet, even though Mary Keys has carefully arbitrated this debate, it still remains problematic for Alasdair MacIntyre, particularly because of the role rights play in both Maritain and Catholic Social Thought. I examine Keys’ argument and, in addition, Deborah Wallace’s account of MacIntyre’s criticism of rights in Catholic social thought. I argue, in the end, that what Maritain, and in consequence (...) Keys and Wallace, miss about the common good is its relationship to practical reasoning, and that MacIntyre highlights both that relationship and the role of the common good in human dignity. (shrink)

Attention has turned from Hobbes the systematic thinker to his inconsistencies, as the essays in the Hobbes symposium published in the recent volume of Political Theory suggest. Deborah Baumgold, in “The Difficulties of Hobbes Interpretation,” shifted the focus to “the history of the book,” and Hobbes’s method of serial composition and peripatetic insertion, as a major source of his inconsistency. Accepting Baumgold’s method, the author argues that the manner of composition does not necessarily determine content and that fundamental paradoxes (...) in Hobbes’s work have a different provenance, for which there are also contextual answers. Hobbes was a courtier’s client, but one committed early to a materialist ontology and epistemology, and these commitments shackled him in treating the immediate political questions with which he was required to deal, leading to systemic paradoxes in his treatment of natural law, liberty, authorization, and consent. (shrink)

What do we do with Judges? This two-edged word? This ambidextrous book? These ambivalent heroes? The Judges were drawing their last fleeting breaths shipwrecked and scattered upon the shores of historical-critical-grammatical-linear-modernist-masculine interpretation. "The narrative is primitive," they said. "The editors have made a mess," they exclaimed. "The conclusion is really an appendix," another said. Then the bible-acrobats jumped in pretending there was no literary carnage while at the same time drawing our eyes away from the literary carnage. "No, no, there (...) is an order to this disorderly book!" "Gideon is a man of faith," they explained. "Gideon is a sham," others retorted. "Long live the king," they cried. "Oh no, the king will bring down the nation," others said. Enter the latest literary critics and the fresh feminist readers to save the day. And save they have. Barry noted the irony. Cheryl called attention to the elaborate, spiraling labyrinth. Phyllis remembered the forgotten. Mieke heralded the incoherence. Deborah the Bee slings Barak with irony. Cowardly Jephthah sacrifices his virgin daughter immediately after he is filled with the spirit. Blind Samson remains stuck in some adolescent, Pinnochio-like stage milling around the same old vices. The Levite, the man of word and sacrifice, lies to the people and dismembers his wife. To beat it all the myopic narrator joins in lock step with the other blind characters stumbling around in the narrative. What manner of text is this? These Judges, these stories, are even more troubling now that we take them seriously. Now what do we do with Judges? The recent scholarship is most promising, but I think we must press forward, or is that backward, or perhaps to another plan. Perhaps Judges hearkens forward to the postmodern. What would Judges look like if we viewed the story through a postmodern lens? Would we see the text in another dimension? Would we let the characters live and breathe as confusing, confounding, intricate characters? Judges speaks to me. These judges, they teach me. How can I ever forget my reading of Judges? For once I found a text reflecting the madness of faith in my maddening world. For once I saw a text like Pablo. I heard the echo of Umberto. I noted the faint murmurings of Jacques. I danced a most joyous jig with Julia. I saw, up ahead, or was that behind me, or over to the side, Martin's flickering candle. Mieke, meet Jael. Barak, meet Barry. Jacques, meet Gideon. Samson, meet Martin. Umberto, meet the narrator or two or three. Pablo, meet the Levite's wife---sorry, she has no name. (shrink)

OBJETIVO -/- O estudante de Zootecnia e de Veterinária, quando se depara com a produção animal, um dos pilares importantes é a reprodução, uma vez que é a perpetuação da espécie, seja para gerar filhas de uma vaca campeã em produção leiteira e de um touro com rusticidade e com aptidão produtiva de corte, ou mesmo para reposição de um plantel, o mesmo deve estar consciente de que esse ramo é de extrema responsabilidade, já que estará intimamente lidando com a (...) vida e com um investimento que pode gerar lucros em demasia para a propriedade ou, se mal feito o manejo da reprodução, trazer sérios transtornos para a mesma. -/- Nesse trabalho, o estudante revisará os sucessos da puberdade e estacionalidade reprodutiva relacionando-os com os processos endócrinos e os fatores que afetam sua manifestação como os nutricionais, para compreender a maneira ao qual podem ser manipuladas. -/- -/- • _____INTRODUÇÃO -/- A puberdade marca o início da vida reprodutiva do animal, permitindo integrar o indivíduo ao seu ciclo produtivo. A estacionalidade é uma característica de adaptação que algumas espécies desenvolveram para fazer garantir a eficiência da reprodução e a sobrevivência dos filhotes. -/- -/- • _____PUBERDADE -/- A puberdade é atingida quando o animal é capaz de produzir e liberar gametas viáveis e funcionais (férteis). Na fêmea esse fato ocorre na primeira ovulação, que geralmente coincide com a manifestação do comportamento do cio; e nos machos durante a primeira ejaculação com espermatozoides viáveis. -/- Do ponto de vista da produção animal, puberdade prematura ou precoce, é importante para poder permitir a incorporação dos animais ao ciclo produtivo o mais rapidamente possível. No caso de touros holandeses, por exemplo, é desejável que produzam sêmen precocemente para incorporá-los a prova de progênie; nas fêmeas, entretanto, deve-se considerar que nem sempre é conveniente usar o primeiro ciclo ou cio para reprodução. É o caso das marrãs (porcas primíparas), onde é benéfico esperar até o segundo ou terceiro estro para aumentar o tamanho da ninhada. Também pode ser vantajoso esperar que o indivíduo alcance sua maturidade sexual, que ocorre quando a fêmea consegue se reproduzir sem sofrer efeitos adversos. A ovelha nascida na primavera, por exemplo, pode engravidar no outono seguinte e dar à luz no primeiro ano de vida, mas seu crescimento pode ser afetado; o mesmo ocorre com a novilha, em que o acasalamento precoce pode promover distorcia por falta de desenvolvimento pélvico. -/- A puberdade é um processo gradual e está intimamente relacionada à taxa de crescimento e ao metabolismo energético. O recém-nascido usa energia para funções vitais, principalmente termorregulação; esse feito se deve ao fato de os jovens possuírem uma superfície corporal muito elevada em relação ao seu volume. Durante o desenvolvi-mento subsequente dos tecidos também há prioridade no uso de nutrientes, que inicialmente favorecem o desenvolvimento do tecido ósseo e muscular, e uma vez que estes atingem determinado tamanho de acordo com as condições genéticas do indivíduo, inicia-se o desenvolvimento do tecido adiposo, que é indicativa de um reservatório de energia. É importante ressaltar que existe uma interação entre a genética e o meio ambiente, de forma que o potencial genético só será expresso se o meio ambiente for favorável. -/- Para que a ovulação ocorra, é necessário considerar o funcionamento do eixo hipotálamo-hipófise-gonodal. O aumento da frequência pulsátil do GnRH hipotalâmico e em consequência do LH hipofisário provoca a maturação do folículo em nível gonodal, o que aumenta a produção de estrógenos. O aumento dos estrogênios causa, por feedback positivo no hipotálamo, a liberação do pico pré-ovulatório de LH e, consequentemente, a ovulação. Na fase pré-púbere, a frequência dos pulsos de GnRH e LH é muito baixa e insuficiente para provocar a maturação folicular, pois o hipotálamo é inibido e, portanto, não ocorre ovulação. -/- A geração pulsátil de GnRH no momento reprodutivo adequado para desencadear o início da puberdade depende de uma rede neural complexa que, além dos neurônios GnRH, inclui outros neurônios e células da glia; ele também integra vários sinais internos e externos para o corpo. A morfologia dos neurônios GnRH também é única, uma vez que seus dendritos também podem funcionar como axônios, dando-lhes uma função distinta. A geração de pulsos também indica a necessidade de sincronização entre subpopulações de neurônios GnRH, que, acima de tudo, parece ser extrínseca a esses neurônios e envolve múltiplos hormônios e neurotransmissores -/- Se dois níveis de conexões aferentes são considerados, estima-se que cada neurônio de GnRH pode ser conectado a cerca de cinco milhões de outros neurônios; milhares de genes, então, podem estar envolvidos no processo da puberdade. A importância funcional e hierárquica de cada um desses genes no controle dos neurônios GnRH, juntamente com outros fatores neuronais e gliais, pode diferir entre as espécies. Existem, no entanto, componentes fundamentais que parecem ser comuns a todos os mamíferos e que se situam nos níveis hierárquicos mais elevados, ajudando a compreender a progressão do processo puberal. Assim, todas as espécies de mamíferos estudadas, por exemplo, têm aglomerados de neurônios kisspeptinérgicos (que secretam kisspeptina), envolvidos na regulação da secreção tônica e secreção cíclica de GnRH, que também se classifica como o elemento mais alto na hierarquia desse complexo neuronal após considerar os neurônios GnRH. -/- Sabe-se que o eixo hipotálamo-hipofisário-gonodal está ativo desde as primeiras fases da vida do indivíduo, mesmo antes do nascimento em certas espécies. A secreção de GnRH, no entanto, é suprimida mais tarde no desenvolvimento e permanece dessa forma até o período pré-púbere, quando será reativada gradualmente. -/- Por várias décadas, a supressão e reinicialização dos pulsos de GnRH foi atribuída a uma hipótese conhecida como teoria gonadostat que afirma que o centro tônico do hipotálamo é inibido devido à sua sensibilidade ao mecanismo de feedback negativo dos esteroides gonodais, é aumentado; portanto, o GnRH e a consequente secreção de gonadotrofinas (FSH e LH) são insuficientes para a ocorrência da maturação folicular e espermatogênese. Essa sensibilidade diminui progressivamente à medida que a puberdade se aproxima. -/- Sabe-se agora que existem fatores não gonodais que agem em paralelo com os esteroides para mediar mudanças no feedback negativo que também são específicos da espécie. -/- Na fêmea, o centro gerador de pulso cíclico também deve ser considerado, o qual é responsável por iniciar a primeira ovulação. O centro cíclico é composto por uma segunda subpopulação de neurônios GnRH que é reativada por meio de uma complexa interação entre vários sistemas neuronais inibitórios (que devem reduzir progressiva-mente sua influência) e outros sistemas excitatórios, que, por sua vez, operam por meio de diferentes neurotransmissores, como o ácido γ-amino-butírico (GABA) e seus receptores, glutamato, óxido nítrico e neuropeptídio Y (NPY). Esses fatores, juntamente com as alterações morfológicas observadas nos neurônios do GnRH à medida que a puberdade se aproxima, e com as interações e sinais aferentes das células gliais, levam a um padrão de progressão linear que culminará na reativação do centro cíclico. Esse processo era conhecido anteriormente como teoria da maturação central e faz parte das mudanças que configuram o processo para chegar à puberdade. A elevação nas concen-trações de estradiol subsequente à reativação gradual do centro gerador de pulso tônico GnRH provavelmente permitirá a maturação final do centro cíclico. -/- A forma como cada organismo estabelece o momento certo para iniciar as mudanças que levam à puberdade é conhecido; a existência de algum mecanismo neurobiológico que constitui um relógio interno pode ser considerada. No entanto, esse mecanismo afetaria principalmente o desenvolvimento neuronal no nível central; também seria difícil compará-lo com a maneira pela qual fatores externos ao indivíduo afetam o início da puberdade. Nessa perspectiva, um sistema que permita receber informações completas sobre o crescimento e desenvolvimento do indivíduo poderia ser mais prático. Os mediadores desse sistema incluem o hormônio do crescimento, IGF-I, leptina e outros substratos metabólicos. A leptina em particular, que sinaliza as reservas de tecido adiposo, é um dos elementos mais importantes e, embora não determine quando começa a puberdade, se atua como fator permissivo para que o processo progrida, uma vez que excede um nível limite. A consideração do estágio de desenvolvimento do animal para o início da puberdade era anteriormente conhecida como o peso corporal crítico ou teoria do lipostato. É importante considerar que as três teorias mencionadas não são exclusivas. -/- O mecanismo da puberdade nos machos é semelhante ao já descrito; entretanto, deve-se lembrar que no macho o centro cíclico não está ativo. À medida que a puberdade se aproxima, o crescimento testicular é desencadeado e, em ruminantes e suínos, o pênis que estava preso à mucosa prepucial é gradualmente liberado. -/- -/- • _____FATORES QUE INFLUENCIAM A PUBERDADE -/- Os animais podem manifestar a puberdade de três formas diferentes. Pode ser tardia e o animal demorar para estar apto a reprodução; precoce e o animal entrar na vida reprodutiva antes do esperado ou pode ser normal e o animal estar com boa conformação e idade. Para tanto, alguns fatores podem interferir à manifestação da puberdade pelos animais como a genética, idade e peso, nutrição, fotoperíodo e o próprio manejo adotado. -/- -/- Genética -/- O genótipo afeta a idade da puberdade, pois algumas raças são anteriores a outras. Nos bovinos, as raças europeias atingem a puberdade antes dos zebuínos, isto é, uma novilha ou novilho da raça holandesa atinge a puberdade primeiro que os animais da mesma idade e do mesmo peso da raça nelore, por exemplo. -/- Da mesma forma, as porcas da raça chinesa Meishan atingem a puberdade por volta dos 115 dias de idade, metade da idade das raças brancas. As ovelhas de raças de corte, da mesma forma, são mais precoces que os produtores de lã. As raças pequenas, da mesma forma, são geralmente mais precoces, pelo menos em bovinos (jersey x guzerá) e em caninos. Os híbridos, por outro lado, apresentam puberdade mais precoce que os puros, devido ao efeito da heterose. Por este motivo, em certas espécies são utilizadas linhas híbridas. -/- -/- Idade e peso -/- A tabela 1 mostra a idade média de início da puberdade em espécies domésticas. O peso vivo (PV) adulto é mais relevante para a idade na puberdade nos ruminantes, enquanto em suínos é menos decisivo. A tabela também apresenta a porcentagem de peso corporal necessária para a puberdade ocorrer de forma natural. -/- -/- Tabela 1: Idade e peso a puberdade das espécies domésticas -/- Espécie -/- Fêmea (meses) -/- Macho (meses) -/- PV adulto (%) -/- Gado holandês -/- 11 (8-15) -/- 11 (7-18) -/- 30-40 -/- Gado brahman -/- 19 -/- 17 -/- 45-60 -/- Caprinos e ovinos -/- 7 (4-14) -/- 7 (6-9) -/- 40-60 -/- Suínos -/- 6 (5-7) -/- 7 (5-8) -/- 75 -/- Equinos -/- 18 (12-19) -/- 14 (10-24) -/- - -/- Caninos -/- 12 (6-24) -/- 9 (5-12) -/- - -/- Felinos -/- 8 (4-12) -/- 9 (8-10) -/- - -/- Fonte: VALENCIA, 2018. -/- Nutrição -/- Como a puberdade está relacionada à taxa de crescimento, os animais que recebem uma nutrição adequada e balanceada apresentarão puberdade em uma idade mais jovem, ou seja, mais precocemente; ao contrário, a puberdade será tardia nos animais que sofreram restrição alimentar, que estão desnutridos ou que tiveram seu crescimento afetado por doenças infecciosas ou parasitárias. A superalimentação também não é recomendada, pois pode alterar tanto os sinais que são recebidos pelo hipotálamo quanto sua resposta a eles. -/- Logo, o manejo alimentar adotado deve estar de acordo com as normas estabeleci-das pelos especialistas na área, principalmente no tocante as exigências nutricionais que devem servir de regra na propriedade. Sendo assim, os animais entrarão em puberdade com as taxas de alta qualidade o que afetará positivamente na prole futura e dará retorno lucrativo ao proprietário. -/- -/- Época do ano (Fotoperíodo) -/- Em fêmeas de espécies sazonais, como ovelhas e cabras, existem certos requisitos de fotoperíodo que devem ser atendidos para que a puberdade ocorra. Nessas espécies, um período de exposição a dias longos é necessário, seguido por outro de exposição a dias curtos. Na verdade, os cordeiros e cabritos nascidos fora da estação, mesmo que tenham atingido o peso necessário, terão que esperar até o outono seguinte (a estação reprodutiva) para atingir a puberdade. Os machos, por outro lado, não estão sujeitos a essas limitações nos requisitos fotoperiódicos para apresentar a puberdade. -/- Em novilhas nascidas no outono, por outro lado, a puberdade ocorre antes de um ano de idade, no verão seguinte ou no início do outono, mais cedo do que nas nascidas na primavera, devido à exposição a longos dias durante os primeiros seis meses do ano após seu nascimento aceleram seu crescimento. Em gatos, o aumento do fotoperíodo também acelera o início da puberdade. -/- Em ovelhas e novilhas, a primeira ovulação que ocorre ao entrar na puberdade é silenciosa; ou seja, não é acompanhada de sinais comportamentais de cio como a micção frequente, inchamento da vulva, uma montando a outra e deixando-se montar etc., pois para que esse comportamento se manifeste, o sistema nervoso necessita de uma pré-sensibilização com progesterona que não estará presente até o próximo ciclo, após o desenvolvimento do corpo lúteo vindo desta primeira ovulação. -/- -/- Sociossexual -/- A interação de indivíduos da mesma espécie ou a presença ou ausência de sinais de bioestimulação, como feromônios, pode afetar o período de puberdade. A puberdade, por exemplo, é atrasada em porcas criadas individualmente em comparação com porcas criadas em grupo. Além disso, na porca, ovelha e cabra, a exposição ao macho estimula as fêmeas e a puberdade aparece mais precocemente. -/- -/- Manejo -/- Certas práticas de manejo podem acelerar a puberdade, especialmente no período pré-púbere. Em porcas próximas à puberdade, por exemplo, o estresse causado por procedimentos, como o transporte de um local para outro ou a exposição ao macho, faz com que apareça o estro em torno de sete dias após a realização do manejo mencionado. -/- -/- • _____ESTACIONALIDADE REPRODUTIVA -/- A estacionalidade ou sazonalidade reprodutiva é uma estratégia evolutiva que se desenvolveu em algumas espécies; tende a tornar a reprodução mais eficiente. Nos países de latitudes distantes do equador, o objetivo é que as crias nasçam na primavera, época do ano mais favorável, graças à abundância de alimentos e às amenas condições climáticas. No caso da ovelha, cuja gestação dura cinco meses, para que os partos ocorram na primavera, ela deve engravidar no outono (figura 1), quando os dias são curtos; enquanto a égua, tendo uma gestação de aproximadamente 11 meses, deve conceber na primavera, quando os dias são longos; assim, o parto ocorrerá na primavera do ano seguinte (figura 2). -/- -/- Figura 1: Esquema ilustrativo da estacionalidade reprodutiva na espécie ovina. Fonte: PIRES et al., 2011. -/- -/- Esta característica evolutiva desenvolvida pela seleção natural na maioria das espécies silvestres e ainda é conservado por algumas espécies domésticas, como ovelhas, cabras, cavalos e gatos. Em bovinos e suínos, ao contrário, a domesticação levou à perda quase total da estacionalidade reprodutiva. -/- A estacionalidade reprodutiva é codificada nos genes; significa então que a seleção natural favoreceu a propagação de genes que permitiam acoplar a hora do nascimento com a melhor época do ano, por isso passou a ser considerada um método anticoncepcional natural. -/- -/- Figura 2: ciclo reprodutivo anual em espécies estacionais; onde são apresentados os períodos de gestação e a forma como se agrupam os nascimentos, independentemente da época reprodutiva da espécie, em vermelho as fêmeas estão apresentando estro ou cio. Fonte: VALENCIA, 2018. -/- -/- Fotoperíodo -/- Para sincronizar o período fértil com a época mais favorável do ano, a maioria das espécies sazonais usa o fotoperíodo (quantidade de luz diária ao longo do ano). -/- Este sinal ambiental é seguro, confiável e se repete a cada ano. Ovinos e caprinos se reproduzem na época do ano em que os dias são curtos e os equinos quando são longos. O grau de sazonalidade depende da origem da raça. As raças nativas de países localizados em latitudes elevadas (> 50°,ovelhas: soay, blackface, suffolk; cabras: saanen, alpino francês, toggenburg; equinos: puro-sangue, hanoveriano) terão uma estacionalidade mais acentuada do que as latitudes menores ou mediterrâneas (ovelhas: merino; cabras: murciana granadina; equinos: quarto de milha). Também existem raças de latitudes próximas ao Equador cuja estacionalidade é baixa ou nula (ovelhas: raças de pelo, crioulas; cabras: raças africanas e asiáticas) (tabela 2). -/- Para a maioria das raças de ovinos e caprinos, a estação reprodutiva começa no final do verão e início do outono; caracteriza-se pela apresentação de ciclos estrais sucessivos, e termina no final do inverno, quando se inicia o anestro, que se caracteriza pela ausência de ovulação. Nos equinos, ocorre o contrário, uma vez que a estação reprodutiva ocorre na primavera e no verão. -/- -/- Tabela 2: Relação entre a origem da raça e o grau de estacionalidade ou sazonalidade -/- Espécie -/- Alta -/- Média -/- Baixa -/- Ovinos -/- Suffolk, raças britânicas de lã e corte -/- Merino -/- Pelibuey, crioulas -/- Caprinos -/- Saanen, alpino, toggenburg -/- Murciana granadina -/- Crioula -/- Equinos -/- Puro-sangue, hanoveriano, quarto de milha -/- - -/- Crioula, burros -/- Fonte: VALENCIA, 2018. -/- -/- Mecanismo neuroendócrino da estacionalidade -/- Durante o período de anestro, o fotoperíodo exerce efeito inibitório sobre o centro tônico do GnRH no hipotálamo, diminuindo a frequência de pulso. Consequentemente, a pulsatilidade do LH também diminui, que agora é incapaz de induzir a maturação folicular, o aumento dos estrogênios, o pico pré-ovulatório de LH e, portanto, a ovulação. -/- Isso ocorre porque durante o anestro a sensibilidade do hipotálamo ao mecanismo de feedback negativo dos estrogênios e de outros fatores de origem não gonodal é aumentada. Ao aproximar-se da estação reprodutiva, a sensibilidade hipotalâmica diminui e o aumento da pulsatilidade do GnRH causa as mudanças que culminam na ovulação. Portanto, o mecanismo endócrino do anestro estacional é semelhante ao do anestro pré-púbere e de alguns outros tipos de anestro. -/- A estacionalidade é um bom exemplo da interação entre o meio ambiente e o sistema neuroendócrino, pois o organismo é capaz de traduzir um sinal externo ambiental, como o fotoperíodo, em um sinal hormonal interno, que neste caso é a melatonina. -/- A glândula pineal secreta melatonina durante as horas de escuridão. Os animais sazonais apresentam um ritmo reprodutivo endógeno, que é regulado por janelas de fotossensibilidade, determinadas por mudanças na duração do dia. O sinal luminoso é captado pela retina e conduzido, via nervo, pelo trato retino-hipotalâmico até o núcleo supraquiasmático, que funciona como o relógio biológico do corpo. Daí o sinal viaja para o núcleo para-ventricular, depois para o gânglio cervical e, finalmente, para a glândula pineal, que responde secretando melatonina (figura 3). -/- Nas ovelhas, a estação reprodutiva começa quando a duração do dia diminui e, naturalmente, a noite aumenta; na égua, ocorre quando os dias se alongam. -/- A primavera não é necessariamente a melhor época do ano em todas as regiões do globo. Nas latitudes tropicais, a primavera coincide com a seca e não com a abundância de forragem, aspecto a ser levado em consideração ao programar a reprodução. -/- Outro ponto importante a considerar é que as raças europeias sazonais mantêm sua estacionalidade no Brasil. -/- -/- Figura 3: Mecanismo do fotoperíodo em ovinos e a melatonina. Fonte: HAFEZ, 2004. -/- -/- Estacionalidade no macho -/- O macho é menos afetado que a fêmea pelas mudanças típicas de cada época do ano, já que sua função reprodutiva não é necessariamente interrompida durante o anestro ou repouso sexual, embora a produção de hormônios reprodutivos, tamanho e tônus testicular, a libido, as características qualitativas e quantitativas do ejaculado e a fertilidade do esperma podem ser diminuídas. O nível de afetação depende do grau de sazonalidade da raça e da latitude. Por fim, os efeitos do fotoperíodo devem ser separados dos nutricionais, que também variam com a época do ano. -/- -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- -/- BEARDEN, Henry Joe et al. Reproducción animal aplicada. México: Manual Moderno, 1982. -/- BROOKS, P. H.; COLE, D. J. A. The effect of the presence of a boar on the attainment of puberty in gilts. Reproduction, v. 23, n. 3, p. 435-440, 1970. -/- CARDOSO, Daniel; DE PAULA NOGUEIRA, Guilherme. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas. Arquivos de Ciências Veterinárias e Zoologia da Unipar, v. 10, n. 1, 2007. -/- CHEMINEAU, P. et al. Induction and persistence of pituitary and ovarian activity in the out-of-season lactating dairy goat after a treatment combining a skeleton photoperiod, melatonin and the male effect. Reproduction, v. 78, n. 2, p. 497-504, 1986. -/- CLARKE, Iain J. et al. Kisspeptin and seasonality in sheep. Peptides, v. 30, n. 1, p. 154-163, 2009. -/- CORTEEL, J. M. Production, storage and insemination of goat semen. In: Management and Reproduction in Sheep and Goats Symposium, Madison, Wis. (USA), 1977. University of Wisconsin, 1977. -/- CUNNINGHAM, James. Tratado de fisiologia veterinária. Elsevier Health Sciences, 2011. -/- CUPPS, Perry T. (Ed.). Reproduction in domestic animals. Elsevier, 1991. -/- DUKES, Henry Hugh; SWENSON, Melvin J.; REECE, William O. Dukes fisiologia dos animais domésticos. Editora Guanabara Koogan, 1996. -/- DÝRMUNDSSON, Ó. R.; LEES, J. L. Effect of rams on the onset of breeding activity in Clun Forest ewe lambs. The Journal of Agricultural Science, v. 79, n. 2, p. 269-271, 1972. -/- EBLING, F. J. P.; FOSTER, D. L. Photoperiod requirements for puberty differ from those for the onset of the adult breeding season in female sheep. Reproduction, v. 84, n. 1, p. 283-293, 1988. -/- FIELDS, Michael J.; SAND, Robert S.; YELICH, Joel V. (Ed.). Factors affecting calf crop: Biotechnology of reproduction. CRC Press, 2001. -/- HAFEZ, Elsayed Saad Eldin; HAFEZ, Bahaa. Reprodução animal. São Paulo: Manole, 2004. -/- HUGHES, P. E.; PHILIP, G.; SISWADI, R. The effects of contact frequency and transport on the efficacy of the boar effect. Animal Reproduction Science, v. 46, n. 1-2, p. 159-165, 1997. -/- KARSCH, FRED J. et al. Neuroendocrine basis of seasonal reproduction. In: Proceedings of the 1983 Laurentian Hormone Conference. Academic Press, 1984. p. 185-232. -/- LINCOLN, G. A.; SHORT, R. V. Seasonal breeding: nature's contraceptive. In: Proceedings of the 1979 Laurentian Hormone Conference. Academic Press, 1980. p. 1-52. -/- MELLO, Raquel Rodrigues Costa. Puberdade e maturidade sexual em touros bovinos. Agropecuária Científica no Semiárido, v. 10, n. 3, p. 11-28, 2015. -/- MEZA‐HERRERA, C. A. et al. Neuroendocrine, metabolic and genomic cues signalling the onset of puberty in females. Reproduction in Domestic Animals, v. 45, n. 6, p. e495-e502, 2010. -/- MONTEIRO, Claudia Dias; BICUDO, Sony Dimas; TOMA, Hugo Shisei. Puberdade em fêmeas ovinas. Pubvet, v. 4, p. Art. 850-857, 2010. -/- OLIVEIRA, Daniel de Jesus Cardoso de. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas da raça Nelore. 2006. Tese de Doutorado em Medicina Veterinária. Universidade de São Paulo. -/- OLSTER, DEBORAH H.; FOSTER, DOUGLAS L. Control of gonadotropin secretion in the male during puberty: a decrease in response to steroid inhibitory feedback in the absence of an increase in steroid-independent drive in the sheep. Endocrinology, v. 118, n. 6, p. 2225-2234, 1986. -/- PIRES, Bruno Carlos et al. Métodos para elevar o ritmo reprodutivo dos ovinos. PUBVET, Londrina, V. 5, N. 11, Ed. 158, Art. 1071, 2011. -/- PLANT, Tony M.; ZELEZNIK, Anthony J. (Ed.). Knobil and Neill's physiology of reproduction. New York: Academic Press, 2014. -/- RAMIREZ, Domingo V.; MCCANN, S. M. Comparison of the regulation of luteinizing hormone (LH) secretion in immature and adult rats. Endocrinology, v. 72, n. 3, p. 452-464, 1963. -/- ROSER, JANET F.; HUGHES, JOHN P. Seasonal effects on seminal quality, plasma hormone concentrations, and GnRH‐induced LH response in fertile and subfertile stallions. Journal of andrology, v. 13, n. 3, p. 214-223, 1992. -/- SALOMONI, Eduardo et al. Idade e peso à puberdade em fêmeas de corte puras e cruzas em campo natural. Pesquisa Agropecuária Brasileira, v. 23, n. 10, p. 1171-1179, 1988. -/- SMITH, Jeremy T.; CLARKE, Iain J. Seasonal breeding as a neuroendocrine model for puberty in sheep. Molecular and cellular endocrinology, v. 324, n. 1-2, p. 102-109, 2010. -/- VALENCIA, J. Pubertad y estacionalidad reproductiva. In. PORTA, L. R.; MEDRANO, J. H. H. Fisiología reproductiva de los animales domésticos. Cidade do México: FMVZ-UNAM, 2018. -/- WHITTEMORE, Colin et al. The science and practice of pig production. Blackwell Science Ltd, 1998. -/- -/- -/- FIXAÇÃO DO ASSUNTO -/- -/- 1. Defina o que é puberdade e como ela manifesta-se no corpo. -/- -/- -/- 2. Diferencie puberdade de maturidade sexual. -/- -/- -/- 3. Quais são os fenômenos que devem ser observados em fêmeas que estão entrando na puberdade? -/- -/- -/- 4. Qual o papel do GnRH e do IGF-I sobre a puberdade? -/- 5. Um produtor possui duas ovelhas e um carneiro reprodutor, as ovelhas possuem idade e peso, mas não manifestaram seu primeiro cio, quais elementos que você recomenda ao produtor para induzir a ciclicidade dessas fêmeas? -/- -/- -/- 6. De forma geral, quais os fatores que podem afetar a entrada na puberdade dos animais? -/- -/- -/- 7. Defina estacionalidade reprodutiva. -/- -/- -/- 8. O que é fotoperíodo e qual sua importância para a reprodução dos animais domésticos? -/- -/- -/- 9. Defina as relações existentes entre a origem da raça e o grau de estacionalidade e como tais teorias se aplicam ao rebanho brasileiro. -/- -/- -/- 10. Qual o papel da glândula pineal para a estacionalidade reprodutiva? -/- -/- -/- 11. Por que os machos são menos afetados pela sazonalidade reprodutiva do que as fêmeas? -/- -/- -/- 12. Sabendo-se sobre os termos de puberdade e estacionalidade e as características de ambos nas espécies domésticas, pede-se: um criador deseja obter 5 novas crias ovinas e 5 caprinas em seu plantel até o final do ano, para tanto ele ainda possui um ano e está na estação do verão, sabendo-se sobre a estacionalidade dessas espécies elabore um projeto reprodutivo de modo que essas 10 fêmeas possam gerar uma cria cada até a primavera. -/- -/- Dados: 10 fêmeas gerando 10 crias. 1 macho ovino e 1 caprino. Fêmeas com 1 ano de idade (2º cio) e peso corporal = 55% do peso adulto. Verão de 2020 para parir na primavera de 2020. (shrink)