In this article, I show that the semantics one adopts for mass terms constrains the metaphysical claims one can make about mixtures. I first expose why mixtures challenge a singularist approach based on mereological sums. After discussing an alternative, non-singularist approach, I take chemistry into account and explain how it changes our perspective on these issues.

The Fully Bayesian Significance Test (FBST) is a coherent Bayesian significance test for sharp hypotheses. This paper proposes the FBST as a model selection tool for general mixture models, and compares its performance with Mclust, a model-based clustering software. The FBST robust performance strongly encourages further developments and investigations.

Now with extra footnotes, by editorial demand! Final version accepted by Oxford Studies in Ancient Philosophy. -/- This essay consists in a trick and a potential insight. The trick consists in a minimalist interpretation of color mixture. The account of color mixture is minimalist in the sense that, given certain background assumptions, there is no more to Timaeus’ account of color mixture than the list of the chromatic pathēmata and the list of how these combine to elicit (...) perceptions of all the colors. The only potential controversial elements of the minimalist interpretation are the relevant background assumptions and the interpretation of the chromatic pathēmata. The potential insight concerns a motive that Plato, in the guise of Timaeus, may have for presenting an account of color mixture. Specifically, I shall argue that on the minimalist interpretation, Plato may be read as reconciling the Democritrean four color scheme with an older tradi- tion where white and black are the fundamental chromatic opposition. As we shall see, this bears on the interpretation of the chromatic pathēmata. (shrink)

Inspired by recent progress in multi-agent Reinforcement Learning (RL), in this work we examine the collective intelligent behaviour of theoretical universal agents by introducing a weighted mixture operation. Given a weighted set of agents, their weighted mixture is a new agent whose expected total reward in any environment is the corresponding weighted average of the original agents' expected total rewards in that environment. Thus, if RL agent intelligence is quantified in terms of performance across environments, the weighted (...) class='Hi'>mixture's intelligence is the weighted average of the original agents' intelligences. This operation enables various interesting new theorems that shed light on the geometry of RL agent intelligence, namely: results about symmetries, convex agent-sets, and local extrema. We also show that any RL agent intelligence measure based on average performance across environments, subject to certain weak technical conditions, is identical (up to a constant factor) to performance within a single environment dependent on said intelligence measure. (shrink)

Special issue of the Journal for Early Modern Studies (4.1., Spring 2005) Guest Editor: Lucian Petrescu. -/- .

For Anaxagoras, both before the beginning of the world and in the present, “all is together” and “everything is in everything.” Various modern interpretations abound regarding the identity of this “mixture.” It has been explained as an aggregation of particles or as a continuous “fusion” of different sorts of ingredients. However—even though they are not usually recognized as a distinct group—there are a number of other scholars who, without seemingly knowing each other, have offered a different interpreta- tion: Anaxagoras’ (...) mixture as an “interpenetration” of different ingredients, which are as far-extended as the whole mixture is. As a result, there are different entities occupying the same place at the same time. This explanation assigns to Anaxagoras the same model of mixture which was later used by the Stoics. A new book by Marmodoro helps us to clarify this position. (shrink)

Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixture models, where the number of clusters is predicted via sequential hypothesis tests: at each step, the method considers a mixture model of m components (m = 2 in the first step) and (...) tests if in fact it should be m - 1. If the hypothesis is rejected, m is increased and a new test is carried out. The method continues (increasing m) until the hypothesis is accepted. The theoretical core of the method is the full Bayesian significance test, an intuitive Bayesian approach, which needs no model complexity penalization nor positive probabilities for sharp hypotheses. Numerical experiments were based on a cDNA microarray dataset consisting of expression levels of 205 genes belonging to four functional categories, for 10 distinct strains of Saccharomyces cerevisiae. To analyze the method’s sensitivity to data dimension, we performed principal components analysis on the original dataset and predicted the number of classes using 2 to 10 principal components. Compared to Mclust (model-based clustering), our method shows more consistent results. (shrink)

The data analyzed in this paper are part of the results described in Bueno et al. (2000). Three cytogenetics endpoints were analyzed in three populations of a species of wild rodent – Akodon montensis – living in an industrial, an agricultural, and a preservation area at the Itajaí Valley, State of Santa Catarina, Brazil. The polychromatic/normochromatic ratio, the mitotic index, and the frequency of micronucleated polychromatic erythrocites were used in an attempt to establish a genotoxic profile of each area. It (...) was assumed that the three populations were in the same conditions with respect to the influence of confounding factors such as animal age, health, nutrition status, presence of pathogens, and intra- and inter-populational genetic variability. Therefore, any differences found in the endpoints analyzed could be attributed to the external agents present in each area. The statistical models used in this paper are mixtures of negative-binomials and Poisson variables. The Poisson variables are used as approximations of binomials for rare events. The mixing distributions are beta densities. The statistical analyzes are under the bayesian perspective, as opposed to the frequentist ones often considered in the literature, as for instance in Bueno et al. (2000). (shrink)

Can we maintain that purple seems composed of red and blue without giving up the impenetrability of the red and blue parts that compose it? Brentano thinks we can. Purple, according to him, is a chessboard of red and blue tiles which, although individually too small to be perceived, are together indistinctly perceived within the purple. After a presentation of Brentano’s solution, we raise two objections to it. First, Brentano’s solution commits him to unperceivable intentional objects (the chessboard’s tiles). Second, (...) his chessboard account fails in the end to explain the phenomenal spatial continuity of compound colours. We then sketch an alternative account, which, while holding fast to the phenomenal compoundedness of the purple and to the impenetrability of component colours, avoids introducing inaccessible intentional objects and compromising on the continuity of the purple. According to our proposal, instead of being indistinctly perceived spatial parts of the purple, red and blue are distinctly perceived non- spatial parts of it. (shrink)

This paper presents Duns Scotus’s theory of mixture in the context of medieval discussions over Aristotle’s theory of mixed bodies. It revisits the accounts of mixture given by Avicenna, Averroes, and Thomas Aquinas, before presenting Scotus’s account as a reaction to Averroes. It argues that Duns Scotus rejected the Aristotelian theory of mixture altogether and that his account went contrary to the entire Latin tradition. Scotus denies that mixts arise out of the four classical elements and he (...) maintains that both the elemental forms and the elemental qualities are lost in the mixture. Consequently, he denies the distinction between the process of mixture and that of substantial change through generation and corruption. The reassessment of Scotus’s account modifies the current historical representation of this discussion, inherited from Anneliese Maier. (shrink)

This article describes the Full Bayesian Significance Test for the problem of separate hypotheses. Numerical experiments are performed for the Gompertz vs. Weibull life span test.

The Fully Bayesian Significance Test (FBST) is a coherent Bayesian significance test for sharp hypotheses. This paper explores the FBST as a model selection tool for general mixture models, and gives some computational experiments for Multinomial-Dirichlet-Normal-Wishart models.

We review the history of the philosophy of fondue since Aristotle so as to arrive at the formulation of the paradox of Swiss fondue. Either the wine and the cheese cease to exist (Buridan), but then the fondue is not really a mixture of wine and cheese. Or the wine and the cheese continue to exist. If they do, then either they continue to exist in different places (the chemists), but then a fondue can never be perfectly homogenous (it (...) is a French fondue). Or the wine and the cheese continue to exist in the same place (the Stoïcs), but then wine and cheese have to be, oddly, penetrable and spatially expansible. Aristote attempted to solve this paradox by arguing that the cheese and wine continue to exist, but only potentially in the fondue. We sketch an alternative answer. The wine and the cheese continue to exist, but only non-spatially in the fondue. Wine and cheese, once mixed, become non-spatial constituents of the fondue, a bit like character traits are non-spatial constituents of persons. The wine and the cheese are in the fondue, but only the fondue is there in the fondue pot. (shrink)

This paper is a tentative step towards a historical cognitive science, in the domain of memory and personal identity. I treat theoretical models of memory in history as specimens of the way cultural norms and artifacts can permeate ('proto')scientific views of inner processes. I apply this analysis to the topic of psychological control over one's own body, brain, and mind. Some metaphors and models for memory and mental representation signal the projection inside of external aids. Overtly at least, medieval and (...) Renaissance theorists agreed that such models had to allow for, or even guarantee, some conception of cognitive order and discipline. Individual memory traces had to be independent, not mixed up or interfering with others. The long tradition of improving or bypassing 'natural memory' by deliberately internalizing artefactual models was part of an arduous process of self-fashioning. Moral panic about confusion and mixture features centrally in the imposition of cognitive discipline in local memory traditions. (shrink)

An important problem with machine learning is that when label number n>2, it is very difficult to construct and optimize a group of learning functions, and we wish that optimized learning functions are still useful when prior distribution P(x) (where x is an instance) is changed. To resolve this problem, the semantic information G theory, Logical Bayesian Inference (LBI), and a group of Channel Matching (CM) algorithms together form a systematic solution. MultilabelMultilabel A semantic channel in the G theory consists (...) of a group of truth functions or membership functions. In comparison with likelihood functions, Bayesian posteriors, and Logistic functions used by popular methods, membership functions can be more conveniently used as learning functions without the above problem. In Logical Bayesian Inference (LBI), every label’s learning is independent. For Multilabel learning, we can directly obtain a group of optimized membership functions from a big enough sample with labels, without preparing different samples for different labels. A group of Channel Matching (CM) algorithms are developed for machine learning. For the Maximum Mutual Information (MMI) classification of three classes with Gaussian distributions on a two-dimensional feature space, 2-3 iterations can make mutual information between three classes and three labels surpass 99% of the MMI for most initial partitions. For mixture models, the Expectation-Maxmization (EM) algorithm is improved and becomes the CM-EM algorithm, which can outperform the EM algorithm when mixture ratios are imbalanced, or local convergence exists. The CM iteration algorithm needs to combine neural networks for MMI classifications on high-dimensional feature spaces. LBI needs further studies for the unification of statistics and logic. (shrink)

The mixture of political, social, cultural and economic environments in Latin America, together with the enormous diversity in climates, natural habitats and biological resources the continent offers, make the ethical assessment of agricultural policies extremely difficult. Yet the experience gained while addressing the contemporary challenges the region faces, such as rapid urbanization, loss of culinary and crop diversity, extreme inequality, disappearing farming styles, water and land grabs, malnutrition and the restoration of the rule of law and social peace, can (...) be of great value to other regions in similar latitudes, development processes and social problems. This chapter will provide a brief overview of these challenges from the perspective of a continent that is exposed to the consequences of extreme inequality in multiple dimensions and conclude by arguing for the need to have a continuous South-South dialogue on the challenges of establishing socially and environmentally sustainable food systems. (shrink)

In Brazilian conditions of bovines creation in semi-extensive and essentially extensive systems, the animals present irregular performance depending on the time of year. During the waters station, that is, the rainy season, the animals perform better; notwithstanding, during dry rain-scarce periods, meat and milk production declines sharply, animals lose weight and the growth rhythm of steers and heifers is reduced. This occurs at the expense of the surplus or lack of forage in the pasture that the animals have access to. (...) Ruminants, thanks to the physiological particularities of their gastrointestinal tract, can synthesize a good part of the vitamins they need, nonetheless, are summarily dependents on the intake of minerals to maintenance the production and good development osseous, muscular etc. The mineralization or supplementation of cattle herds is an zootechnical practice of extreme importance from a practical and economic perspective, since if longs of to maximize animal productivity. Given this context, takes on is that the correct formulation of mineral salt or multiple mixtures containing scarce minerals in roughage or concentrates is extremely important, since correct supplementation aims to increase fertility, improve the herd's feeding efficiency and prevent the manifestation of diseases related to mineral deficiency. Keywords: Supplementation, Minerals, Multiple mixture, Requirements, Cattle. -/- . (shrink)

College towns contain mixtures of students and locals, tied to the intitution’s urban life. Due to students’ health, community engagement must be prioritized in these towns. However, technology is often blamed for distancing people. A paradoxical use of it, specifically immersive technology, a youth favorite, can be the solution by focusing on the technological narratives of the institute-related materials to improve community cohesion. This strategy shaped connections between students and locals and among past, present, and future. In this presentation, the (...) impact of immersive technology will be discussed and compared in two college towns, Lancaster, UK, and Lubbock, USA. (shrink)

Today, we have a mixture of young and older individuals, people with special needs, and people who can care for themselves. Over 1 billion people are estimated to be disabled; this figure corresponds to about 15% of the world's population, with 3.8% (approximately 190 million people) accounting for people aged 15 and up (Organization, 2011). The number of people with disabilities is upward due to the increase in chronic health conditions and many other things. These and other factors have (...) made the need for proper care facilities urgent in today's society. Several care facilities are built to help people with disabilities live their everyday lives and not be left out of the community. (shrink)

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be made more complicated (...) in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

You see a cherry and you experience it as red. A textbook explanation for why you have this sort of experience is going to cite such things as the cherry’s chemical surface properties and the distinctive mixture wavelengths of light it is disposed to reflect. What does not show up in this explanation is the redness of the cherry. Many allege that the availability of color-free explanations of color experience somehow calls into question our beliefs about the colors of (...) objects around us. We explore how such explanations are supposed to undermine color beliefs, and in particular whether evolutionary considerations have any special role to play. (shrink)

The aim of this text, derived from an investigation, is to propose a reflection on the future of the university, from the problematization of the neoliberal rationality impact on the forms of knowledge production and organization of academic life. To develop this analysis, the main transformations of the modern university since its advent with the founding of the Berlin University by Wilhelm von Humboldt, in 1810, who created the model of the research university, until the emergence of the neoliberal university (...) model. The purpose of the article is to highlight the rationalities that govern the transformation of the university over time. This historical analysis attempts to demonstrate that no model can be considered natural, absolute, inevitable, non-negotiable, and that and that the university as an institution is inhabited by a mixture of contradictory rationalities. To conclude, the Derrida's essay (2001), is used to show that the uncontested adoption of the neoliberal model can destroy the autonomy of research and teaching that until today characterized the modern university, and compromise its mission in the future. (shrink)

During the eighteenth century, German philosophers wrote on a broad range of topics in moral philosophy: from meta-ethical issues such as the nature of obligation, to elaborate systems of normative ethics (often in the form of a doctrine of duties to self, others, and God), to topics in applied ethics such as the permissibility of the death penalty and censorship. Moral philosophy was also intimately related to the modern natural law tradition at the time, as well as to discussions taking (...) place in theology and psychology, to name only a few other disciplines. As a result, it is often hard to isolate eighteenth-century German moral philosophy without addressing a whole host of other philosophical subjects. There are nonetheless certain central topics that were discussed by nearly every major figure of the period and which therefore serve as a window into how German philosophers approached moral philosophy during the eighteenth century. In this chapter I illustrate that one such topic is the principle of morality; namely what philosophers took to be the supreme norm at the foundation of judging actions to be morally good or evil. As we will see, although several figures approached this principle in a broadly similar way by identifying “perfection” as the central concept at work, they differ considerably with respect to important details. Furthermore, certain common threads reveal themselves: philosophers differ not only with respect to the content of the principle, but also with respect to the way in which it can be derived, how particular duties can in turn be derived from the supreme principle, and how the principle can be formulated. I begin by outlining Christian Wolff’s influential principle of perfection (Section 1), followed by a consideration of Alexander Gottlieb Baumgarten’s subtle revision of this principle (Section 2) and Christian August Crusius’s theological alternative (Section 3). I then briefly consider the impact that the reception of eighteenth-century British philosophy had on German moral philosophy during the second half of the eighteenth century (Section 4), before considering Moses Mendelssohn’s and Immanuel Kant’s answers to the 1763 Prize Essay Question (Section 5) and Johann August Eberhard’s unique mixture of rationalism and empiricism from the early 1780s (Section 6). I conclude (Section 7) with a brief discussion of Kant’s approach to the principle of morality and the principle of happiness proposed against it by his early empiricist critics. (shrink)

I defend a one category ontology: an ontology that denies that we need more than one fundamental category to support the ontological structure of the world. Categorical fundamentality is understood in terms of the metaphysically prior, as that in which everything else in the world consists. One category ontologies are deeply appealing, because their ontological simplicity gives them an unmatched elegance and spareness. I’m a fan of a one category ontology that collapses the distinction between particular and property, replacing it (...) with a single fundamental category of intrinsic characters or qualities. We may describe the qualities as qualitative charactersor as modes, perhaps on the model of Aristotelian qualitative (nonsubstantial) kinds, and I will use the term “properties” interchangeably with “qualities”. The qualities are repeatable and reasonably sparse, although, as I discuss in section 2.6, there are empirical reasons that may suggest, depending on one’s preferred fundamental physical theory, that they include irreducibly intensive qualities. There are no uninstantiated qualities. I also assume that the fundamental qualitative natures are intrinsic, although physics may ultimately suggest that some of them are extrinsic. On my view, matter, concrete objects, abstract objects, and perhaps even spacetime are constructed from mereological fusions of qualities, so the world is simply a vast mixture of qualities, including polyadic properties (i.e., relations). This means that everything there is, including concrete objects like persons or stars, is a quality, a qualitative fusion, or a portion of the extended qualitative fusion that is the worldwhole. I call my view mereological bundle theory. (shrink)

It is proposed that our memory is made up of individual, unconnected Records, to each of which is attached a Heading. Retrieval of a Record can only be accomplished by addressing the attached Heading, the contents of which cannot itself be retrieved. Each Heading is made up of a mixture of content in more or less literal form and context, the latter including specification of environment and of internal states (e.g. drug states and mood). This view of memory allows (...) an easy account of a number of natural memory phenomena as well as a variety of laboratory findings such as the differences between recall and recognition. The theory further proposes that Headed Records can neither be deleted nor modified. Data apparently against such a hypothesis can be accounted for in terms of the retrieval process. (shrink)

Aristotle introduced in the history of the reception of Anaxagoras the term “homoiomerous.” This word refers to substances whose parts are similar to each other and to the whole. Although Aristotle’s explanations can be puzzling, the term “homoiomerous” may explain an authentic aspect of Anaxagoras’ doctrine reflected in the fragments of his work. Perhaps one should find a specific meaning for the term “homoiomerous” in Anaxagoras, somewhat different from the one present in Aristotle. This requires a review of the sense (...) of the two terms involved in it: “homoios” and “moira.” In other words, the following questions should be answered: what realities are named parts and to what whole do they belong? On the other hand, which similarity do they have to each another and to the whole? The author concludes that the parts are “all things,” which resemble each other and the universe as a whole because, according to Anaxagoras, they are all composed of all things. (shrink)

Abstract: Heart diseases are increasing daily at a rapid rate and it is alarming and vital to predict heart diseases early. The diagnosis of heart diseases is a challenging task i.e. it must be done accurately and proficiently. The aim of this study is to determine which patient is more likely to have heart disease based on a number of medical features. We organized a heart disease prediction model to identify whether the person is likely to be diagnosed with a (...) heart disease or not using the medical features of the person. We used many different algorithms of machine learning such as Gaussian Mixture, Nearest Centroid, MultinomialNB, Logistic RegressionCV, Linear SVC, Linear Discriminant Analysis, SGD Classifier, Extra Tree Classifier, Calibrated ClassifierCV, Quadratic Discriminant Analysis, GaussianNB, Random Forest Classifier, ComplementNB, MLP Classifier, BernoulliNB, Bagging Classifier, LGBM Classifier, Ada Boost Classifier, K Neighbors Classifier, Logistic Regression, Gradient Boosting Classifier, Decision Tree Classifier, and Deep Learning to predict and classify the patient with heart disease. A quite helpful approach was used to regulate how the model can be used to improve the accuracy of prediction of heart diseases in any person. The strength of the proposed model was very satisfying and was able to predict evidence of having a heart disease in a particular person by using Deep Learning and Random Forest Classifier which showed a good accuracy in comparison to the other used classifiers. The proposed heart disease prediction model will enhances medical care and reduces the cost. This study gives us significant knowledge that can help us predict the person with heart disease. The dataset was collected from Kaggle depository and the model is implemented using python. (shrink)

In recent years, the notion of wilderness has been roundly criticized by several prominent environmental philosophers and historians. They argue that the “received wilderness idea” is dualistic, ethnocentric, and static. According to these critics, this idea of wilderness finds clear expression in the Wilderness Act of 1964. However, the idea of wilderness so ably deconstructed by its critics bears little resemblance to the understanding of wilderness presented in the Wilderness Act. The critics assume a backward-looking, purity-based definition of wilderness that (...) runs counter to the forward-looking, relativistic interpretation of the Wilderness Act that has guided and informed subsequent wilderness legislation, management, and visitation. Under the Wilderness Act, wilderness designation is less a matter of preserving remnants of “pristine” nature than establishing a covenant between humans and a particular place. Wilderness areas, so conceived, serve as potential sabbath places, whose ultimate significance is best understood in terms of their mutually informing relationship to the places where we live and work. Rather than detracting from our efforts to inhabit the Earth in more creative and sustainable ways, wilderness represents a vital part of larger landscapes of human inhabitation characterized by a diverse mixture of human-nature relational patterns. (shrink)

This paper investigates the relationship between some corpuscularian and Aristotelian strands that run through the thought of the sixteenth-century philosopher and physician Julius Caesar Scaliger. Scaliger often uses the concepts of corpuscles, pores, and vacuum. At the same time, he also describes mixture as involving the fusion of particles into a continuous body. The paper explores how Scaliger’s combination of corpuscularian and non-corpuscularian views is shaped, in substantial aspects, by his response to the views on corpuscles and the vacuum (...) in the work of his contemporary, Girolamo Fracastoro. Fracastoro frequently appears in Scaliger’s work as an opponent against whom numerous objections are directed. However, if one follows up Scaliger’s references, it soon becomes clear that Scaliger also shares some of Fracastoro’s views. Like Scaliger, Fracastoro suggests corpuscularian explanations of phenomena such as water rising in lime while at the same time ascribing some non-corpuscularian properties to his natural minima. Like Scaliger, Fracastoro maintains that there is no vacuum devoid of bodies since places cannot exist independently of bodies (although their opinions diverge regarding how exactly the relevant dependency relation might be explicated). Finally, like Scaliger, Fracastoro connects a continuum view of mixture with a theory of natural minima. (shrink)

There is a commonly made distinction between two types of scientists: risk-taking, trailblazing mavericks and detail-oriented followers. A number of recent papers have discussed the question what a desirable mixture of mavericks and followers looks like. Answering this question is most useful if a scientific community can be steered toward such a desirable mixture. One attractive route is through credit incentives: manipulating rewards so that reward-seeking scientists are likely to form the desired mixture of their own accord. (...) Here I argue that this idea is less straightforward than it may seem. Interpreting mavericks as scientists who prioritize rewards over speed and risk, I show in a deliberatively simple model that there is a fixed mixture which is not particularly likely to be desirable and which credit incentives cannot alter. I consider a way around this result, but this has some major drawbacks. I conclude that credit incentives are not as promising a way to create a desirable mixture of mavericks and followers as one might have thought. (shrink)

Zurvanism was an ancient variant of Zoroastrianism. According to Zurvanism, the great powers of good and evil, Ahura Mazda and Angra Mainyu, were the sons of a greater god Zurvan, associated with time. According to Eudemus of Rhodes, some Persian thinkers, presumably Zurvanists, took there to be three great principles underlying the world: light, darkness, and greatest of all time (or perhaps, according to Eudemus, space). This paper explores what metaphysics might underlie these doctrines, and what contemporary options we have (...) for making sense of a metaphysics where time is the ultimate principle. Among the options explored is the option that despite appearance many of the entities of the concrete world are identical to stretches of time, or are somehow aspects of stretches of time; that they include times as parts, or are included in times as parts; that they are somehow properties of time; or hylomorphic compounds of which time is the matter; that the world is somehow a mixture of time, light, and dark; or that somehow the ends or teloi of everyday objects and processes are to be found among good, evil, and time. (shrink)

Sixteenth century pharmacology was still very much under the influence of a distinction going back to ancient medicine: the distinction between effects of medicaments that were taken to be explainable by the elementary qualities, their mutual modification in mixture, and the combination of these modified elementary qualities on the one hand, and the effects of medicaments that were taken not to be explicable in this manner.1 Galen coined the expression that a medicament of the latter kind possesses the capacity (...) of acting "by its whole substance,"2 and the question of how actions of the whole substance could be explicated gave rise to heated controversies in early modern pharmacology. Did Galen just... (shrink)

Heraclitus uses paradoxical language to present the relationship between opposites in his worldview. This mode of expression has generated much controversy. Some take the paradoxes as evidence of a contradictory identity of opposites (Barnes), while others propose a dynamic union through transformation without identity that avoids the contradiction (Graham). By examining B88 and B62, I seek to identify the stronger and weaker points of such readings. The contradictory identity reading thwarts the transformation between opposites. The dynamic reading offers a plausible (...) alternative. However, it skips a characterization of how Heraclitus conceives of the transformation between opposites in physical terms. To fill this gap, I consider Heraclitus’ use of what I call the anti-cognate internal object in B62. I argue that ‘living the death and dying the life’ is a case of change as mixture, a popular conception among the early Presocratics. Upon closer examination, the anti-cognate internal object suggests that real contradictions belong to Heraclitus conception of change. The details reveal a philosophically compelling view. (shrink)

This article investigates the relationships between forms of humor that conjure up possible worlds and real-world social critiques. The first part of the article will argue that subversive humor, which is from or on behalf of historically and continually marginalized communities, constitutes a kind of aesthetic experience that can elicit enjoyment even in adversarial audiences. The second part will be a connecting piece, arguing that subversive humor can be constructed as brief narrative thought experiments that employ the use of fictionalized (...) scenarios to facilitate an open, playful attitude, encouraging a space for collaborative interpretation. This interaction between humorist and audience is an aesthetic experience that is enjoyable in and of itself, as the feelings of mirth are intrinsically valuable. But connected to the “Ha-ha!” experience of these sorts of humorous creations is an “Aha!” or potentially revelatory experience that is a mixture of cognitive comprehension and motivated (emotional) response. The third part of the article will attempt to go beyond the consciousness-raising element with an account of how such possible worlds created in the realm of imagination through subversive humor can bleed into the real world of flesh and blood people. Finally, an example of subversive humor will be analyzed. (shrink)

In this paper, a novel experimental task is developed for testing the highly influential, but experimentally underexplored, possible worlds account of conditionals (Stalnaker, 1968; Lewis, 1973). In Experiment 1, this new task is used to test both indicative and subjunctive conditionals. For indicative conditionals, five competing truth tables are compared, including the previously untested, multi-dimensional possible worlds semantics of Bradley (2012). In Experiment 2, these results are replicated and it is shown that they cannot be accounted for by an alternative (...) hypothesis proposed by our reviewers. In Experiment 3, individual variation in truth assignments of indicative conditionals is investigated via Bayesian mixture models that classify participants as following one of several competing models. As a novelty of this study, it is found that a possible worlds semantics of Lewis and Stalnaker is capable of accounting for participants’ aggregate truth value assignments in this task. Applied to indicative conditionals, we show across three experiments, that the theory both captures participants’ truth values at the aggregate level (Experiments 1 and 2) and that it makes up the largest subgroup in the analysis of individual variation in our experimental paradigm (Experiment 3). (shrink)

Should voting be compulsory? This question has recently gained the attention of political scientists, politicians and philosophers, many of whom believe that countries, like Britain, which have never had compulsion, ought to adopt it. The arguments are a mixture of principle and political calculation, reflecting the idea that compulsory voting is morally right and that it is will prove beneficial. This article casts a sceptical eye on the claims, by emphasizing how complex political morality and strategy can be. Hence, (...) I show, while there are good reasons to worry about voter turnout in established democracies, and to worry about inequalities of turnout as well, the case for compulsory voting is unpersuasive. (shrink)

Using the perspective of situated cognition we studied how people interact with a physical map to help them navigate through an unfamiliar environment. The study used a mixture of cognitive ethnography and traditional experimental methods. We found that the difference between high and low performing navigators showed up in the speed they completed their task and also in the way they use maps. High performers plan routes using a survey method whereas low performers use a route strategy. We suggest (...) that when people are given a task that does not match their cognitive style they try to transform the task to better suit their cognitive abilities and cognitive style. (shrink)

Contemporary biology has inherited two key assumptions from the Modern Synthesis about the nature of population lineages: sexual reproduction is the exemplar for how individuals in population lineages inherit traits from their parents, and random mating is the exemplar for reproductive interaction. While these assumptions have been extremely fruitful for a number of fields, such as population genetics and phylogenetics, they are increasingly unviable for studying the full diversity and evolution of life. I introduce the “mixture” account of population (...) lineages that escapes these assumptions by dissolving the Modern Synthesis’s sharp line separating reproduction and development and characterizing reproductive integration in population lineages by the ephemerality of isolated subgroups rather than random mating. The mixture account provides a single criterion for reproductive integration that accommodates both sexual and asexual reproduction, unifying their treatment under Kevin de Queiroz’s generalized lineage concept of species. The account also provides a new basis for empirically assessing the effect of random mating as an idealization on the empirical adequacy of population genetic models. (shrink)

We provide conditions under which an incomplete strongly independent preorder on a convex set X can be represented by a set of mixture preserving real-valued functions. We allow X to be infi nite dimensional. The main continuity condition we focus on is mixture continuity. This is sufficient for such a representation provided X has countable dimension or satisfi es a condition that we call Polarization.

In its simplest form, a Spritz is an aperitif made with (sparkling) water and (white) wine. A ‘gunky Spritz’, as I will call it, is a Spritz in which the water and the wine are mixed through and through, so that every proper part of the Spritz has a proper part containing both water and wine. In the literature on the notion of location the possibility of mixtures like a gunky Spritz has been thought of as either threatening seemingly intuitive (...) locative principles, or as requiring the position of multiple primitive locative relations. In this paper I present a new theory of location which assumes as primitive only the notion of pervasive location and show that it can account for the possibility of gunky Spritz in an intuitive and adequate way. (shrink)

As one would expect, Kant believes that there is a tension, and even a conflict, between our bodily humanity and its ethical counterpart: ‘Inclination to pleasurable living and inclination to virtue are in conflict with each other’ (Anthropology, 185-86 [7:277]). What is more unexpected, however, is that he further claims that this tension can be resolved in what he calls an example of ‘civilised bliss’, namely dinner parties. Dinner parties are, for Kant, part of the ‘highest ethicophysical good’, the ultimate (...) resolution of the conflict between our physical body and our moral powers, which consists in finding the right proportions for the ‘mixture’ between our partly ‘sensuous’ and partly ‘ethicointellectual’ nature. The aim of this paper is not only to explain Kant’s account of the ideal proportions of ethicophysical good in dinner parties, but also, and more importantly, to argue that dinner parties are in fact the ultimate experience for us, human beings. (shrink)

Most of the theories of location on the market appear to be ideologically parsimonious at least in the sense that they take as primitive just one locative notion and define all the other locative notions in terms of it. Recently, however, the possibility of some exotic metaphysical scenarios involving gunky mixtures and extended simple regions of space has been argued to pose a significant threat to parsimonious theories of locations. The aim of this paper is to show that a theory (...) taking as primitive a notion of plural pervasive location and allowing for irreducibly plural locative facts can account for all the putatively problematic scenarios for parsimonious theories of location. Furthermore, I will also argue that the notion of plural pervasive location is compatible with the possibility of multilocation. (shrink)

Encyclopedia entry about Anaxagoras, the presocratic philosopher: Life, works, mixture, nous, biological and cosmological problems, and a bibliography.

Cassava and soybean flour were used to produce biscuits in different ratios in an attempt to substitute or replace wheat. Composite flour, made from a combination of cassava and soybean flour, was processed into biscuits using varying proportions. The ratios ranged from 10% to 50% soybean flour and 90% to 50% cassava flour. The proximate evaluation revealed that including 20% soybean flour in the cassava flour, making up 80% of the mixture, resulted in a significant level of protein and (...) other nutrients that closely compared to those found in 100% wheat flour. The protein and fat content increased significantly as the proportion of soy flour increased, leading to a corresponding decrease in the carbohydrate content of the analyzed biscuit samples. This study demonstrates that a blend of 80% cassava flour and 20% soy flour produced biscuits with good nutritional quality. The sensory evaluation and overall acceptance of the product showed no significant difference between the 80:20 blend and the control (100% wheat). (shrink)

Transhumanists, like other elites in modernity, place great value on human creativity, and advances in human enhancement and AI form the basis of their propos- als for boosting it. However, there are problems with this perspective, due to the unique ways in which humans have evolved, procreated and socialized. I first describe how creativity is related to past evolution and developmental aspects in children, stressing pretend play and the ambivalent character of creativity. Then, I outline proposals for enhancing creativity, be (...) it in embodied humans on the way to a superior species, in AI- related beings (virtual reality, robotics), or even in any degree of mixture in human- machine interaction. In the final section, I describe intrinsic limits to these proposals, such as the absence of a good understanding of human psychology by the proponents of enhancement; the lack of interest in the subjective side of creativity (for one’s own sake); delayed maturation and the ambivalence of pretend play in childhood; and the contrariness typical of new human generations. As for the enhancement of creativity, it is argued that creativity in its social context may be the victim of its own past success. On the other hand, an asymmetry between virtual beings and children is described— the latter can behave in a nasty way, it is part of their growth and creativity, whereas the former are not supposed to cause any harm to human beings. In sum, despite impressive progress in several scientific and technological interventions in creativity, philosophical questions emerge that place many constraints on transhumanist dreams of endless creativity. (shrink)

Sostengo en este artículo que no somos utilitaristas consecuentes en todo momento, ni deontologistas dogmáticos irracionales, más bien, una mezcla de utilitarismo y deontologismo que depende de una serie de factores no descubiertos o explicados convincentemente tanto epigenéticos, evolutivos, como educacionales, axiológicos, psicológicos aprendidos, conscientes e inconscientes en la toma de decisiones. También argumento que no es lo mismo toma de decisión, que construcción del juicio moral. El juicio moral no siempre conduce a la toma de decisión. Se puede tener (...) un juicio, pero no necesariamente actuar en consecuencia. / I argue in this article that we are not consistent utilitarians at all times, nor irrational dogmatic deontologists, rather, a mixture of utilitarianism and deontologism that depends on a series of factors undiscovered or convincingly explained both epigenetic, evolutionary, as educational, axiological, psychological learned, conscious and unconscious in decision making. I also argue that decision making is not the same as constructing moral judgment. The second does not always lead to the first. I can have a trial, but not necessarily act accordingly. (shrink)

Plastic waste is a significant environmental problem for almost all countries; therefore, protecting the environment from the problem is crucial. The most sensible solution to these problems is substituting the natural aggregates with substantial plastic waste in various building materials. This study aimed to optimise the mixed design ratio of cement brick containing plastic waste as aggregate replacement. Plastic cement brick mixtures were prepared by the incorporation of four different types of plastic waste such as polyethylene terephthalate (PET), high-density polyethylene, (...) low-density polyethylene and polypropylene into cement bricks with different cement contents (150, 300 and 450 g) and plastic replacement percentages (0, 3 and 6%). Compressive strength and water absorption of the plastic cement bricks were analysed using a statistical model through the response surface methodology. It revealed the optimum cement brick mixed design is C3-1% PET with the compressive strength of 27.50 MPa and water absorption of 1.16%. The optimised plastic cement brick also satisfied the general ASTM C62-17 requirements for building bricks despite the higher porosity observed by the scanning electron microscopy. The results from Fourier transform infrared spectroscopy analysis also showed that the addition of the plastic waste into cement brick was unlikely to modify the chemical compound within the cement brick mixtures. Thus, the proposed mathematical model can predict the required hardened properties of plastic cement bricks and could lead to greater utilisation of plastic waste in building materials. (shrink)

A strongly independent preorder on a possibly in finite dimensional convex set that satisfi es two of the following conditions must satisfy the third: (i) the Archimedean continuity condition; (ii) mixture continuity; and (iii) comparability under the preorder is an equivalence relation. In addition, if the preorder is nontrivial (has nonempty asymmetric part) and satisfi es two of the following conditions, it must satisfy the third: (i') a modest strengthening of the Archimedean condition; (ii') mixture continuity; and (iii') (...) completeness. Applications to decision making under conditions of risk and uncertainty are provided. (shrink)

La finalidad del presente ensayo consiste en partir de las nociones interrelacionadas de "capitalismo mundial integrado" (Guattari) y de "sociedad de control" (Deleuze) para intentar una deriva que cruce géneros, épocas y nombres propios: de la filosofía al cine y a la poesía (caminos de ida y vuelta), de Benjamin a Serres pasando por Homero, Kavafis, Cioran o Godard, del tardío imperio romano y sus incertidumbres a la imprecisión de nuestro propio tiempo. Posiblemente, pensar hoy la identidad humana sea como (...) nunca antes un asunto de mezcla, de viaje a través de territorios viejos que demandan una nueva cartografía. -/- The purpose of this essay is to depart from the interrelated notions of "whole global capitalism" (Guattari) and the "control society" (Deleuze) to attempt a drift across genders, epochs and proper names: from philosophy to cinema and poetry (roundtrip roads), from Benjamin to Serres, passing through Homer, Kavafis, Cioran or Godard, from the late Roman empire and its uncertainties to our own time. Possibly, thinking today about human identity is as never before, a matter of mixture, of travel through old territories that demand new maps. (shrink)