A main goal of the neuroscience of consciousness is: find the neural correlate to conscious experiences (NCC). When have we achieved this goal? The answer depends on our operationalization of “NCC.” Chalmers (2000) shaped the widely accepted operationalization according to which an NCC is a neural system with a state which is minimally sufficient (but not necessary) for an experience. A deeper look at this operationalization reveals why it might be unsatisfactory: (i) it is not an operationalization of a correlate (...) for occurring experiences, but of the capacity to experience; (ii) it is unhelpful for certain cases which are used to motivate a search for neural correlates of consciousness; (iii) it does not mirror the usage of “NCC” by scientists who seek for unique correlates; (iv) it hardly allows for a form of comparative testing of hypotheses, namely experimenta crucis. Because of these problems (i–iv), we ought to amend or improve on Chalmers's operationalization. Here, I present an alternative which avoids these problems. This “NCC2.0” also retains some benefits of Chalmers's operationalization, namely being compatible with contributions from extended, embedded, enacted, or embodied accounts (4E-accounts) and allowing for the possibility of non-biological or artificial experiencers. (shrink)

The violation of Bell inequalities by quantum physical experiments disproves all relativistic micro causal, classically real models, short Local Realistic Models (LRM). Non-locality, the infamous “spooky interaction at a distance” (A. Einstein), is already sufficiently ‘unreal’ to motivate modifying the “realistic” in “local realistic”. This has led to many worlds and finally many minds interpretations. We introduce a simple many world model that resolves the Einstein Podolsky Rosen paradox. The model starts out as a classical LRM, thus clarifying that the (...) many worlds concept alone does not imply quantum physics. Some of the desired ‘non-locality’, e.g. anti-correlation at equal measurement angles, is already present, but Bell’s inequality can of course not be violated. A single and natural step turns this LRM into a quantum model predicting the correct probabilities. Intriguingly, the crucial step does obviously not modify locality but instead reality: What before could have still been a direct realism turns into modal realism. This supports the trend away from the focus on non-locality in quantum mechanics towards a mature structural realism that preserves micro causality. (shrink)

A central objection to McDowell’s conceptualism about empirical content concerns the fine-grained phenomenology of experience, which supposedly entails that the actual content of experience cannot be matched in its particularity by our concepts. While McDowell himself has answered this objection in recourse to the possibility of demonstrative concepts, his reply has engendered a plethora of further objections and is widely considered inadequate. I believe that McDowell’s critics underestimate the true force of his reply because they tend to read unrecognized empiricist (...) presuppositions into his account of experience. To show this, I introduce a new hylomorphic reading of McDowell’s account of experience and argue that the objections to his reply all rest on a specific empiricist assumption, which is untenable because it conflates the form of experience with its content. Consequently, conceptualism so understood can resist all of these objections, as I attempt to show by systematizing and answering them. (shrink)

On some accounts, prostitution is just another form of casual sex and as such not particularly harmful in itself, if regulated properly. I claim that, although casual sex in general is not inher-ently harmful, prostitution in fact is. To show this, I defend an account of sex as joint action characteristically aimed at sexual enjoyment, here understood as a tangible experience of com-munity among partners, and argue that prostitution fails to achieve this good by incentivizing partners to mistreat each other. (...) To substantiate this claim, I explore ways in which prostitution fails on the virtues of temperance, respect, and sincerity. (shrink)

Unter einigenWissenschaftlern ist die Vorstellung verbreitet, dass Paradoxien Anzeichen von Fortschritt sein können. Es ist jedoch unklar, wie dies zu deuten ist. Dieser Essay stellt ein subjekt-relatives Verständnis von Paradoxikalität vor, das Paradoxien als »Dissonanzen der Zustimmung« (Rescher 2001) charakterisiert und dadurch erlaubt, sie als Katalysator wissenschaftlichen Fortschritts zu rekonstruieren: Durch ihre Struktur haben Problemstellungen in Form von Paradoxien wenigstens fünf fortschrittsfördernde Eigenschaften, die sie Problemstellungen in Form von Fragen voraushaben. Dadurch können Paradoxien als Angelpunkte theoretischen Fortschritts gesehen werden. Dies (...) legt eine Forderung nahe: Wenn wir theoretischen Fortschritt in den Wissenschaften fördern wollen, so sollten wir den Bau von Paradoxien aktiv verfolgen, gemäß dem Credo: Progress by Paradox! (shrink)

The present paper aims to contribute to the substantivalism versus relationalism debate and to defend general relativity (GR) against pseudoscientific attacks in a novel, especially inclusive way. This work was initially motivated by the desire to establish the incompatibility of any ether theories with accelerated cosmic expansion and inflation (motto: where would a hypothetical medium supposedly come from so fast?). The failure of this program is of interest for emergent GR concepts in high energy particle physics. However, it becomes increasingly (...) important to guard scientific results against their misrepresentation by fundamentally anti-scientific agendas. We therefore argue that although it is not known whether the perceived space-time is fundamental (rather than a condensed state or a particular membrane), in a fundamental theory, space-time must be abstract relational: fundamental space-time is the consistent spatial-temporal arrangement of events. To pursue its own goals, this work should be accessible to a wide audience: physicists, philosophers of science, those being tempted by anti-relativity theories, but also those who vigorously defend some orthodox relativity that is not actually supported by GR. It must thus be extensive in order to satisfy the different parties’ desire to have included and understood their respective positions. (shrink)

There is tension between commonly held views concerning phenomenal imagery on the one hand and our first-person epistemic access to it on the other. This tension is evident in many individual issues and experiments in philosophy and psychology (e.g. inattentional and change blindness, the speckled hen, dream coloration, visual periphery). To dissolve it, we can give up either (i) that we lack full introspective access to the phenomenal properties of our imagistic experiences, or (ii) that phenomenal imagery is fully determined, (...) or (iii) that phenomenal imagery does not exist. Which option is preferable? I explore the feasibility of option (ii) in more details by distinguishing between di erent kinds of indeterminacy. One of the most often proclaimed versions of indeterminacy is tied to Representationalism. However, I argue that in this context, Representationalism appears to be the least satisfying option, for which I give ten reasons. By abduction, we should reject Representationalism in favour of (i) or (iii)—the most parsimonious option being eliminativism, and the most conservative being the rejection of privileged access. The decision between these two, however, should be made on a case-by-case basis, depending on which is most adequate given the data. I illustrate this with the comparison between visual agnosia and Charles-Bonnet-Syndrome. (shrink)

The paper aims to give an account of practical knowledge by outlining a hylomorphic and conceptualist account of intentional action in analogy to McDowell's conceptualist account of experience. On this view, practical concepts provide the ideal or formal structure that unifies a manifold of bodily movements into a single intentional action, and hence intentional actions are structured conceptually. -/- - §1 sets out the basic features of this view in contrast to a common dualistic or two-component view of practical knowledge, (...) as an "inner" mental state with propositional content that functions as the efficient cause of some bodily movement in the "external" world, and introduces the claim that practical knowledge is the constitutive form of intentional action. - §2 illustrates the hylomorphic unity of concept and movement in action, and thus (contra Dreyfus) the corporeality of practical reason, by means of an account of practical concept formation, on which both the formation and tradition of practical concepts take place in bodily movement iself. - §3 elucidates the concept of a self-conscious disposition or rational capacity for action, actualizations of which are characterized by a syllogistic structure that accounts for both the explanation and the justification of action and thereby renders intelligible in what sense practical judgment is internal to acting itself. - Skillful exercises of such capacities express a knowledge-how that manifests itself in practical representations. §4 characterizes representations of this kind as a perceptually situated recognition of a practical pattern that amounts to the imaginative anticipation of a movement form by which the agent determines their next steps; a practical perception of the agent's particular situation that is both normative and motivational for them. - §5 starts by developing an identity theory of practical truth, on which the conceptual content of a (true) practical judgment is numerically identical with the formal structure of a (good) action, and concludes with explaining the unity of four features commonly attributed to practical knowledge, viz. that it is at the same time descriptive, normative, causally productive, and non-observational (or self-conscious). (shrink)

What is the role of intimacy in sex? The two culturally dominant views on this matter both share the implicit assumption that sex is genuinely intimate only when connected to romance, and hence that sex and intimacy stand in a contingent relationship: it is possible to have good sex without it. Liberals embrace this possibility and affirm the value of casual sex, while conservatives attempt to safeguard intimacy by insisting on romantic exclusivity. I reject their shared assumption and argue for (...) a necessary connection between intimacy and sex, in that sexual activity as such aims at a specific form of intimacy, irrespective of whether it takes place in casual encounters or romantic relationships, and the difference between good and bad sex consists in whether this end is attained. To defend this view, I develop a general account of intimacy, as based on joint action, and apply it to isolate its specifically sexual form. (shrink)

My aims are exegetical rather than critical: I offer a systematic account of Hursthouse's ethical naturalism with an emphasis on the normative authority of the four ends, and try to correct some misconceptions found in the literature. Specifically, I argue that the four ends function akin to Wittgensteinian hinge-propositions for our practice of ethical reasoning and as such form part of a description of the logical grammar of said practice.

In der Diskussion um personale Identität nehmen die einflussreichen Arbeiten Derek Parfits eine Sonderstellung ein, insofern Parfit nicht bestrebt ist, eines der gängigen Identitätskriterien zu verteidigen, sondern vielmehr behauptet, dass unsere alltäglichen wie philosophischen Vorstellungen von personaler Identität unrettbar inkohärent sind und deshalb aufgegeben werden sollten. In seinem Beitrag beleuchtet Sascha Settegast die verschiedenen Argumente, die Parfit für diese provokante These vorbringt, und unternimmt insbesondere den Versuch einer systematischen Dekonstruktion der wichtigsten Gedankenexperimente Parfits, die zeigen soll, dass sich diese (...) Gedankenexperimente auf eine Weise auflösen lassen, die unsere alltäglichen Intuitionen über personale Identität intakt belässt. Settegast entwickelt dabei die Grundzüge einer Konzeption personaler Identität, die sich einerseits von den gängigen neo-lockeanischen und animalistischen Ansätzen abgrenzt und andererseits bewusst an den zeitgenössischen Neo-Aristotelismus in der Ethik anknüpft, wie er etwa bei Philippa Foot und Michael Thomp-son anzutreffen ist. Die diachrone numerische Identität menschlicher Personen gründet nach Settegasts Auffassung darin, dass der Verlauf ihres Lebens eine zeitliche Einheit aufweist, die dadurch bedingt ist, dass ihre Lebensführung die menschliche Lebensform auf eine individuell charakteristische Weise exemplifiziert. Insofern dies aber nur durch Kultivierung der Tugen-den zu erreichen ist, handelt es sich laut Settegast bei personaler Identität letztlich nicht um eine Tatsache, die einfach vorliegt oder nicht, sondern um eine Aufgabe, die uns als Menschen gegeben ist und wesentlich darin besteht, in bewusster Orientierung auf das gute Leben hin ein stabiles, sich zeitlich durchhaltendes Selbst allererst auszubilden. (shrink)

In recent years, the science and the philosophy of consciousness has seen growing interest in structural questions about consciousness. This is the Editorial Introduction for a special volume for Philosophy and the Mind Sciences on “Structuralism in Consciousness Studies.”.

The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means. A particular focus was on ontologies, as these are a key technology to systematically integrate heterogeneous information about the aging process. Related topics were databases and data integration. Other talks tackled modeling issues and applications, the latter including talks focussed on marker development and cellular stress as well as on diseases, in particular on diseases of kidney (...) and skin. (shrink)

Driven by technological innovations, newborn screening (NBS) panels have been expanded and the development of genomic NBS pilot programs is rapidly progressing. Decisions on disease selection for NBS are still based on the Wilson and Jungner (WJ) criteria published in 1968. Despite this uniform reference, interpretation of the WJ criteria and actual disease selection for NBS programs are highly variable. A systematic literature search [PubMED search “Wilson” AND “Jungner”; last search 16.07.22] was performed to evaluate the applicability of the WJ (...) criteria for current and future NBS programs and the need for adaptation. By at least two reviewers, 105 publications (systematic literature search, N = 77; manual search, N = 28) were screened for relevant content and, finally, 38 publications were evaluated. Limited by the study design of qualitative text analysis, no statistical evaluation was performed, but a structured collection of reported aspects of criticism and proposed improvements was instead collated. This revealed a set of general limitations of the WJ criteria, such as imprecise terminology, lack of measurability and objectivity, missing pediatric focus, and absent guidance on program management. Furthermore, it unraveled specific aspects of criticism on clinical, diagnostic, therapeutic, and economical aspects. A major obstacle was found to be the incompletely understood natural history and phenotypic diversity of rare diseases prior to NBS implementation, resulting in uncertainty about case definition, risk stratification, and indications for treatment. This gap could be closed through the systematic collection and evaluation of real-world evidence on the quality, safety, and (cost-)effectiveness of NBS, as well as the long-term benefits experienced by screened individuals. An integrated NBS public health program that is designed to continuously learn would fulfil these requirements, and a multi-dimensional framework for future NBS programs integrating medical, ethical, legal, and societal perspectives is overdue. (shrink)

In Sascha Settegast’s recently published article, “Prostitution and the Good of Sex” in Social Theory and Practice, he argues that prostitution is intrinsically harmful. In this article, I object to his argument, making the following three responses to his account: 1) bad sex is not “detrimental to the good life”; 2) bad sex is not necessarily unvirtuous; 3) sex work is work as well as sex, and so must be evaluated as work in addition to as sex.