Transient Truths: An Essay in the Metaphysics of Propositions provides the first book-length exposition and defense of semantic temporalism, the view that propositions are contents or semantic values that can change their truth-values across time.

Diversity of practice is widely recognized as crucial to scientific progress. If all scientists perform the same tests in their research, they might miss important insights that other tests would yield. If all scientists adhere to the same theories, they might fail to explore other options which, in turn, might be superior. But the mechanisms that lead to this sort of diversity can also generate epistemic harms when scientific communities fail to reach swift consensus on successful theories. In this paper, (...) we draw on extant literature using network models to investigate diversity in science. We evaluate different mechanisms from the modeling literature that can promote transient diversity of practice, keeping in mind ethical and practical constraints posed by real epistemic communities. We ask: what are the best ways to promote an appropriate amount of diversity of practice in scientific communities? (shrink)

This is not a perfect book, but it is unique, and if you skim the first 400 or so pages, the last 300 (of some 700) are a pretty good attempt to apply what's known about behavior to social changes in violence and manners over time. The basic topic is: how does our genetics control and limit social change? Surprisingly he fails to describe the nature of kin selection (inclusive fitness) which explains much of animal and human social life. He (...) also (like nearly everyone) lacks a clear framework for describing the logical structure of rationality (LSR—John Searle’s preferred term) which I prefer to call the Descriptive Psychology of Higher Order Thought (DPHOT). He should have said something about the many other ways of abusing and exploiting people and the planet, since these are now so much more severe as to render other forms of violence irrelevant. Extending the concept of violence to include the global long term consequences of replication of someone’s genes, and having a grasp of the nature of how evolution works (i.e., kin selection) will provide a very different perspective on history, current events, and how things are likely to go in the next few hundred years. One might start by noting that the decrease in physical violence over history has been matched (and made possible) by the constantly increasing merciless rape of the planet (i.e., by people's destruction of their own descendants future). Pinker (like most people most of the time) is often distracted by the superficialities of culture when it’s biology that matters. See my recent reviews of Wilson’s ‘The Social Conquest of Earth’ and Nowak and Highfield’s ‘SuperCooperators’ for a brief summary of the vacuity of altruism and the operation of kin selection and the uselessness and superficiality of describing behavior in cultural terms. -/- Those wishing a comprehensive up to date account of Wittgenstein, Searle and their analysis of behavior from the modern two systems view may consult my article The Logical Structure of Philosophy, Psychology, Mind and Language as Revealed in Wittgenstein and Searle (2016). Those interested in all my writings in their most recent versions may download from this site my e-book ‘Philosophy, Human Nature and the Collapse of Civilization Michael Starks (2016)- Articles and Reviews 2006-2016’ by Michael Starks First Ed. 662p (2016). -/- All of my papers and books have now been published in revised versions both in ebooks and in printed books. -/- Talking Monkeys: Philosophy, Psychology, Science, Religion and Politics on a Doomed Planet - Articles and Reviews 2006-2017 (2017) https://www.amazon.com/dp/B071HVC7YP. -/- The Logical Structure of Philosophy, Psychology, Mind and Language in Ludwig Wittgenstein and John Searle--Articles and Reviews 2006-2016 (2017) https://www.amazon.com/dp/B071P1RP1B. -/- Suicidal Utopian Delusions in the 21st century: Philosophy, Human Nature and the Collapse of Civilization - Articles and Reviews 2006-2017 (2017) https://www.amazon.com/dp/B0711R5LGX . (shrink)

Power transients faults on high voltage lines are prominently due to high frequency transients. These transients affect the predicted life and efficiency of equipment. The Fast Fourier Transform (FFT) is helpful in analysing the effect of high frequencies and Frequency Response Analysis (FRA) provide support in diagnosis and detection of deformation in a transformers. The major aim of this study is to analyse the incorporation of frequencies based on resonating core of a particular transformer. Using transfer function (...) method an impedance change in transformer has been observed when equipment is subjected to high voltage transients. The effect of change in impedance is that it degrade the life of a core with respect to time. In this paper, research that has been done already on Transformers of different ratings i.e. 100, 50 and 30 kVA are studied and then an experiment is performed on 50-kVA transformer. It was concluded that the core of a transformer having rating equal or less than 50 kVA practically shows single resonance behavior while above 50 kVA for instance 100-kVA transformer core resonates twice. In actual, result defines the core deviating frequency with respect to the rating of a transformer. (shrink)

This is not a perfect book, but it is unique, and if you skim the first 400 or so pages, the last 300 (of some 700) are a pretty good attempt to apply what's known about behavior to social changes in violence and manners over time. The basic topic is: how does our genetics control and limit social change? Surprisingly he fails to describe the nature of kin selection (inclusive fitness) which explains much of animal and human social life. He (...) also (like nearly everyone) lacks a clear framework for describing the logical structure of rationality (LSR—John Searle’s preferred term) which I prefer to call the Descriptive Psychology of Higher Order Thought (DPHOT). He should have said something about the many other ways of abusing and exploiting people and the planet, since these are now so much more severe as to render other forms of violence nearly irrelevant. Extending the concept of violence to include the global long-term consequences of replication of someone’s genes, and having a grasp of the nature of how evolution works (i.e., kin selection) will provide a very different perspective on history, current events, and how things are likely to go in the next few hundred years. One might start by noting that the decrease in physical violence over history has been matched (and made possible) by the constantly increasing merciless rape of the planet (i.e., by people's destruction of their own descendant’s future). Pinker (like most people most of the time) is often distracted by the superficialities of culture when it’s biology that matters. See my recent reviews of Wilson’s ‘The Social Conquest of Earth’ and Nowak and Highfield’s ‘SuperCooperators’ here and on the net for a brief summary of the vacuity of ‘true altruism’ (group selection), and the operation of kin selection and the uselessness and superficiality of describing behavior in cultural terms. -/- This is the classic nature/nurture issue and nature trumps nurture --infinitely. What really matters is the violence done to the earth by the relentless increase in population and resource destruction (due to medicine and technology and conflict suppression by police and military). About 200,000 more people a day (another Las Vegas every 10 days, another Los Angeles every month), the 6 tons or so of topsoil going into the sea/person/year –about 1% of the world’s total disappearing yearly, etc. mean that unless some miracle happens the biosphere and civilization will largely collapse during next two centuries, and there will be starvation, misery and violence of every kind on a staggering scale. People's manners, opinions and tendencies to commit violent acts are of no relevance unless they can do something to avoid this catastrophe, and I don't see how that is going to happen. There is no space for arguments, and no point either (yes I'm a fatalist), so I'll just make a few comments as though they were facts. Don't imagine I have a personal stake in promoting one group at the expense of others. I am 78, have no descendants and no close relatives and do not identify with any political, national or religious group and regard the ones I belong to by default as just as repulsive as all the rest. -/- Parents are the worst Enemies of Life on Earth and, taking the broad view of things, women are as violent as men when one considers the fact that women's violence (like most of that done by men) is largely done in slow motion, at a distance in time and space and mostly carried out by proxy -by their descendants and by men. Increasingly, women bear children regardless of whether they have a mate and the effect of stopping one woman from breeding is on average much greater than stopping one man, since they are the reproductive bottleneck. One can take the view that people and their offspring richly deserve whatever misery comes their way and (with rare exceptions) the rich and famous are the worst offenders. Meryl Streep or Bill Gates or J.K Rowling and each of their kids may destroy 50 tons of topsoil each per year for generations into the future, while an Indian farmer and his may destroy 1 ton. If someone denies it that's fine, and to their descendants I say "Welcome to Hell on Earth"(WTHOE). -/- The emphasis nowadays is always on Human Rights, but it is clear that if civilization is to stand a chance, Human Responsibilities must replace Human Rights. Nobody gets rights without being a responsible citizen and the first thing this means is minimal environmental destruction. The most basic responsibility is no children unless your society asks you to produce them. A society or a world that lets people breed at random will always be exploited by selfish genes until it collapses (or reaches a point where life is so horrific it's not worth living). If society continues to maintain Human Rights as primary, to their descendants one can say with confidence "WTHOE". -/- Those wishing a comprehensive up to date framework for human behavior from the modern two systems view may consult my book ‘The Logical Structure of Philosophy, Psychology, Mind and Language in Ludwig Wittgenstein and John Searle’ 2nd ed (2019). Those interested in more of my writings may see ‘Talking Monkeys--Philosophy, Psychology, Science, Religion and Politics on a Doomed Planet--Articles and Reviews 2006-2019 3rd ed (2019), The Logical Structure of Human Behavior (2019), and Suicidal Utopian Delusions in the 21st Century 4th ed (2019) . (shrink)

यह एक आदर्श पुस्तक नहीं है, लेकिन यह अद्वितीय है, और यदि आप पहले 400 या तो पृष्ठों स्किम, पिछले 300 (कुछ 700 के) एक बहुत अच्छा लागू करने के लिए क्या समय के साथ हिंसा और शिष्टाचार में सामाजिक परिवर्तन के व्यवहार के बारे में जाना जाता है प्रयास कर रहे हैं. मूल विषय है: कैसे हमारे आनुवंशिकी नियंत्रण और सामाजिक परिवर्तन की सीमा है? हैरानी की बात है कि वह रिश्तेदार चयन (समावेशी फिटनेस) जो पशु और मानव सामाजिक (...) जीवन के बहुत बताते हैं की प्रकृति का वर्णन करने में विफल रहता है. उन्होंने यह भी (लगभग हर किसी की तरह) तर्कसंगतता की तार्किक संरचना का वर्णन करने के लिए एक स्पष्ट रूपरेखा का अभाव है (LSR-जॉन Searle पसंदीदा शब्द) जो मैं उच्च आदेश सोचा (DPHOT) के वर्णनात्मक मनोविज्ञान फोन पसंद करते हैं. उन्हें लोगों और ग्रह को गाली देने और उनका शोषण करने के कई अन्य तरीकों के बारे में कुछ कहना चाहिए था, क्योंकि ये अब इतने अधिक गंभीर हैं कि हिंसा के अन्य रूपों को लगभग अप्रासंगिक बना दिया गया है। हिंसा की अवधारणा का विस्तार करने के लिएकिसी के जीन की प्रतिकृति के वैश्विक दीर्घकालिक परिणाम शामिल हैं, और कैसे विकास काम करता है की प्रकृति की समझहोने (यानी, रिश्तेदार चयन) इतिहास पर एक बहुत ही अलग परिप्रेक्ष्य प्रदान करेगा , वर्तमान घटनाओं, और कैसे चीजें अगले कुछ सौ वर्षों में जाने की संभावना है. एक ध्यान देने योग्य है कि इतिहास पर शारीरिक हिंसा में कमी मिलान किया गया है द्वारा शुरू हो सकता है (और संभव बनाया) ग्रह की लगातार बढ़ती बेरहम बलात्कार द्वारा (यानी, लोगोंके अपने वंशज के भविष्य के विनाशसे). पिंकर (ज्यादातर लोगों की तरह ज्यादातर समय) अक्सर संस्कृति के सतही से विचलित है जब यह जीव विज्ञान है कि मायने रखती है. विल्सन 'पृथ्वी के सामाजिक विजय' और Nowak और Highfield 'SuperCooperators' यहाँ और नेट पर 'सच परोपकारिता' (समूह चयन) की शून्यता का एक संक्षिप्त सारांश के लिए की मेरी हाल ही की समीक्षा देखें, और रिश्तेदार चयन के संचालन और uselessness और सांस्कृतिक संदर्भ में व्यवहार का वर्णन करने की सतही. यह क्लासिक प्रकृति/पोषण का मुद्दा है और प्रकृति का पोषण --अनंत रूप से। क्या वास्तव में मायने रखती है जनसंख्या और संसाधन विनाश में लगातार वृद्धि (चिकित्सा और प्रौद्योगिकी और पुलिस और सेना द्वारा संघर्ष दमन के कारण) द्वारा पृथ्वी के लिए किया हिंसा है. के बारे में 200,000 अधिक लोगों को एक दिन (एक और लास वेगास हर 10 दिन, एक और लॉस एंजिल्स हर महीने), 6 टन या तो topsoil के समुद्र में जा / कुछ चमत्कार होता है जैवमंडल और सभ्यता काफी हद तक अगली दो शताब्दियोंके दौरान पतन होगा, और वहाँ भुखमरी, दुख और एक चौंका देने वाला पैमाने पर हर तरह की हिंसा होगी. हिंसक कृत्यों को करने के लिए लोगों के व्यवहार, विचारों और प्रवृत्तियों की कोई प्रासंगिकता नहीं है जब तक कि वे इस तबाही से बचने के लिए कुछ नहीं कर सकते हैं, और मुझे नहीं लगता कि यह कैसे होने जा रहा है। वहाँ तर्क के लिए कोई जगह नहीं है, और कोई बात या तो (हाँ मैं एक fatalist हूँ), तो मैं सिर्फ कुछ टिप्पणी कर के रूप में हालांकि वे तथ्य थे. कल्पना मत करो मैं दूसरों की कीमत पर एक समूह को बढ़ावा देने में एक निजी हिस्सेदारी है. मैं 78हूँ, कोई वंशज और कोई करीबी रिश्तेदार है और किसी भी राजनीतिक, राष्ट्रीय या धार्मिक समूह के साथ की पहचान नहीं है और लोगों को मैं डिफ़ॉल्ट रूप से कर रहे हैं के रूप में बस के रूप में बाकी सब के रूपमें प्रतिकर्षण संबंध मानते हैं. माता पिता पृथ्वी पर जीवन का सबसे बुरा दुश्मन हैं और, चीजों की व्यापक दृष्टिकोण ले रही है, महिलाओं के रूप में पुरुषों के रूप में हिंसक जब एक तथ्य यह है कि महिलाओं की हिंसा (पुरुषों द्वारा किया है कि सबसे अधिक की तरह) काफी हद तक धीमी गति में किया जाता है समझता है, समय और अंतरिक्ष में एक दूरी पर और ज्यादातर carri प्रॉक्सी द्वारा बाहर ed - उनके वंशजों द्वारा और पुरुषों द्वारा. तेजी से, महिलाओं के बच्चों को सहन की परवाह किए बिना कि क्या वे एक दोस्त है और प्रजनन से एक औरत को रोकने के प्रभाव औसत पर एक आदमी को रोकने से अधिक है, क्योंकि वे प्रजनन बाधाओं हैं. एक विचार है कि लोगों को और उनकी संतान बड़े पैमाने पर जो कुछ भी दुख के लायक हो उनके रास्ते आता है और (दुर्लभ अपवादों के साथ) अमीर और प्रसिद्ध सबसे खराब अपराधी हैं ले जा सकते हैं. मेरिल स्ट्रीप या बिल गेट्स या जे के Rowling और उनके बच्चों में से प्रत्येक भविष्य में पीढ़ियों के लिए प्रति वर्ष topsoil के 50 टन नष्ट कर सकते हैं, जबकि एक भारतीय किसान और उसके 1 टन नष्ट कर सकते हैं. अगर किसी को यह है कि ठीक है इनकार करते हैं, और उनके वंशजों के लिए मैं कहता हूँ "पृथ्वी पर नरक में आपका स्वागत है" (WTHOE). आजकल जोर हमेशा मानव अधिकारों पर है, लेकिन यह स्पष्ट है कि अगर सभ्यता के लिए एक मौका खड़ा है, मानव जिम्मेदारियों मानव अधिकारों की जगह चाहिए. किसी को भी जिम्मेदार नागरिक होने के बिना अधिकार नहीं मिलता है और इसका सबसे पहला अर्थ है कि यह मानवपर्यावरण विनाशहै. सबसे बुनियादी जिम्मेदारी कोई बच्चों को जब तक अपने समाज आप उन्हें उत्पादन करने के लिए पूछता है. एक समाज या एक दुनिया है कि लोगों को यादृच्छिक पर नस्ल की सुविधा देता है हमेशा स्वार्थी जीन द्वारा शोषण किया जाएगा जब तक यह गिर (या एक बिंदु तक पहुँचता है जहां जीवन इतना भयावह है यह जीने के लायक नहीं है). यदि समाज मानव अधिकारों को प्राथमिक के रूप में बनाए रखताहै, तो उनके वंशजों को विश्वास के साथ "WTHOE" कह सकते हैं। आधुनिक दो systems दृश्यसे मानव व्यवहार के लिए एक व्यापक अप करने के लिए तारीख रूपरेखा इच्छुक लोगों को मेरी पुस्तक 'दर्शन, मनोविज्ञान, मिनडी और लुडविगमें भाषा की तार्किक संरचना से परामर्श कर सकते हैं Wittgenstein और जॉन Searle '2 एड (2019). मेरे लेखन के अधिक में रुचि रखने वालों को देख सकते हैं 'बात कर रहेबंदर- दर्शन, मनोविज्ञान, विज्ञान, धर्म और राजनीति पर एक बर्बाद ग्रह --लेख और समीक्षा 2006-2019 3 एड (2019) और आत्मघाती यूटोपियान भ्रम 21st मेंसदी 4वें एड (2019) . (shrink)

这不是一本完美的书,但它是独特的,如果你浏览前400页左右,最后300页(约700页)是一个很好的尝试,将已知的行为应用于社会变化在暴力和礼仪随着时间的推移。基本的主题是:我们的遗传学如何控制和限制社 会变化？令人惊讶的是,他未能描述亲属选择(包容性健身)的本质,这解释了动物和人类社会生活的很多原因。他还(像几乎每个人都一样)缺乏一个清晰的框架来描述理性的逻辑结构(LSR-John Searle的首选术语),我更愿意称之为高阶思想的描述性心理学(DPHOT)。他应该说一些关于虐待和剥削人和地球的许多其他方式,因为现在这些方式更加严重,以至于使其他形式的暴力几乎无关紧要。扩大暴力的 概念,包括复制某人基因的全球长期后果,并掌握进化过程的性质(即亲属选择),将提供一个完全不同的历史视角,时事,以及未来几百年的情况可能如何发展。人们可能首先指出,历史上身体暴力的减少与地球不断发生的无 情强奸(即人们摧毁自己后代的未来)相吻合(并成为可能)。平克尔(和大多数人一样,大多数时候)常常被文化的肤浅所分心,而生物学才是最重要的。在这里和网上查看我最近对威尔逊的《地球的社会征服》和诺瓦克和高 菲尔德的"超级合作者"的评论,了解"真正的利他主义"(群体选择)的空虚性简要摘要,亲属选择的运作,以及用文化术语描述行为的无用和肤浅。 这是经典的自然/培育问题,自然胜过培育——无限。真正重要的是,人口和资源破坏的无情增加(由于医药和技术以及警察和军队对冲突的镇压),给地球造成了暴力。每天约有20万人(每10天再下一个拉斯维加斯,每月 另一个洛杉矶),6吨左右表土进入大海/人/年——约占全世界每年消失总量的1%,等等,这意味着除非生物圈和文明将在未来两个世纪内大为崩溃,各种饥荒、苦难和暴力将发生惊人规模。 人们实施暴力行为的举止、观点和倾向是没有意义的,除非他们能够做些什么来避免这场灾难,而我看不出这是怎么回事。没有争论的空间,也没有意义(是的,我是一个宿命论者),所以我只做一些评论,好像它们是事实一样 。不要以为我以牺牲他人利益来推销一个团体有个人利益。我78岁,没有后代,没有近亲,不认同任何政治、民族或宗教团体,认为我属于的人,默认和所有其他团体一样令人厌恶。 父母是地球上最可怕的生命敌人,从事物的广义来看,当人们认为女性的暴力(像大多数由男性做的一样)大部分是在慢动作、在时间和空间上保持距离时,女性和男性一样暴力。由代理人 - 由他们的后代和男人。妇女越来越生孩子,无论她们是否有伴侣,阻止一名妇女生育的效果平均远远大于阻止一个男人,因为她们是生殖瓶颈。人们可以认为,无论遭受什么苦难,人们及其后代都值得,(除了极少数例外),富 人和名人是最恶劣的罪犯。梅丽尔·斯特里普或比尔·盖茨或J.K·罗琳和他们每个孩子可能在未来几代人中每年每年销毁50吨表土,而印度农民和他的可能摧毁1吨。如果有人否认那很好,对他们的后代,我说" ;欢迎来到地球上的地狱"(WTHOE)。 现在的重点总是放在人权上,但很明显,如果文明要有机会,人类的责任必须取代人权。没有人没有负责任的公民就得到权利,而这意味着第一件事就是破坏环境。最基本的责任是,除非你的社会要求你生产孩子,否则没有孩子 。一个允许人们随意繁殖的社会或世界总是被自私的基因所利用,直到它崩溃(或者达到生命如此可怕以至于不值得活下去)。如果社会继续以人权为首要,那么对其后代,人们可以满怀信心地说"WTHOE&qu ot;。 那些希望从现代两个系统的观点来看为人类行为建立一个全面的最新框架的人,可以查阅我的书《路德维希的哲学、心理学、Min d和语言的逻辑结构》维特根斯坦和约翰·西尔的《第二部》(2019年)。那些对我更多的作品感兴趣的人可能会看到《会说话的猴子——一个末日星球上的哲学、心理学、科学、宗教和政治——文章和评论2006-20 19年3月(2019年)和21年的自杀乌托邦幻想St世纪4日 (2019) .

Neurovascular coupling (NVC), the transient regional hyperemia following the evoked neuronal responses, is the basis of blood oxygenation level-dependent techniques and is generally adopted across physiological conditions, including the intrinsic resting state. However, the possibility of neurovascular dissociations across physiological alterations is indicated in the literature. To examine the NVC stability across sleep–wake states, we used electroencephalography (EEG) as the index of neural activity and functional magnetic resonance imaging (fMRI) as the measure of cerebrovascular response. Eight healthy adults were recruited (...) for simultaneous EEG-fMRI recordings in nocturnal sleep. We compared the cross-modality (EEG vs. fMRI) consistency of functional indices (spectral amplitude and functional connectivity) among five states of wakefulness and sleep (state effect). We also segregated the brain into three main partitions (anterior, middle and posterior) for spatial assessments (regional effect). Significant state effects were found on δ, α and fMRI indices and regional effects on the α and fMRI indices. However, the cross-state EEG changes in spectral amplitude and functional connectivity did not consistently match the changes in the fMRI indices across sleep–wake states. In spectral amplitude, the δ band peaked at the N3 stage for all brain regions, while the fMRI fluctuation amplitude peaked at the N2 stage in the central and posterior regions. In regional connectivity, the inter-hemispheric connectivity of the δ band peaked at the N3 stage for all regions, but the bilateral fMRI connectivity showed the state changes in the anterior and central regions. The cross-modality inconsistencies across sleep–wake states provided preliminary evidence that the neurovascular relationship may not change in a linear consistency during NREM sleep. Thus, caution shall be exercised when applying the NVC presumption to investigating sleep/wake transitions, even among healthy young adults. (shrink)

In the Critique of the Power of Judgment, Kant remarks that the feeling of the dynamically sublime is actually conditioned and that its foundation is the moral feeling, which he addressed in the Critique of Practical Reason. In order to elucidate those transient yet significant remarks, this paper confronts the analytic of the dynamically sublime from the third Critique with the analytic of the moral feeling from the second Critique. By uncovering an architectonic, constitutive and structural kinship between the two (...) feelings, the paper contributes to the reconsideration of the relation between Kant’s aesthetics and his ethics. (shrink)

Ian Hacking (born in 1936, Vancouver, British Columbia) is most well-known for his work in the philosophy of the natural and social sciences, but his contributions to philosophy are broad, spanning many areas and traditions. In his detailed case studies of the development of probabilistic and statistical reasoning, Hacking pioneered the naturalistic approach in the philosophy of science. Hacking’s research on social constructionism, transient mental illnesses, and the looping effect of the human kinds make use of historical materials to shed (...) light on how developments in the social, medical, and behavioural sciences have shaped our contemporary conceptions of identity and agency. Hacking’s other contributions to philosophy include his work on the philosophy of mathematics (Hacking, 2014), philosophy of statistics, philosophy of logic, inductive logic (Hacking, 1965, 1979, 2001) and natural kinds (Hacking, 1991, 2007a). (shrink)

The paper is an exercise in descriptive ontology, with specific applications to problems in the geographical sphere. It presents a general typology of spatial boundaries, based in particular on an opposition between bona fide or physical boundaries on the one hand, and fiat or human-demarcation-induced boundaries on the other. Cross-cutting this opposition are further oppositions in the realm of boundaries, for example between: crisp and indeterminate, complete and incomplete, enduring and transient, symmetrical and asymmetrical. The resulting typology generates a corresponding (...) categorization of the different sorts of objects which (complete) boundaries determine or demarcate. The theory is applied first of all in the areas of geography and of administrative and property law. Indications are then given as to how the typology may be applied also in other fields where physical and fiat boundaries are at work, including the field of cognitive linguistics and the related field of the ontology of truth. (shrink)

This paper describes one style of functional analysis commonly used in the neurosciences called task-bound functional analysis. The concept of function invoked by this style of analysis is distinctive in virtue of the dependence relations it bears to transient environmental properties. It is argued that task-bound functional analysis cannot explain the presence of structural properties in nervous systems. An alternative concept of neural function is introduced that draws on the theoretical neuroscience literature, and an argument is given to show that (...) this alternative concept of may help to overcome the explanatory limitations of task-bound functional analysis. (shrink)

The right temporo-parietal junction (rTPJ) has been associated with two apparently disparate functional roles: in attention and in social cognition. According to one account, the rTPJ initiates a “circuit-breaking” signal that interrupts ongoing attentional processes, effectively reorienting attention. It is argued this primary function of the rTPJ has been extended beyond attention, through a process of evolutionarily cooption, to play a role in social cognition. We propose an alternative account, according to which the capacity for social cognition depends on a (...) network which is both distinct from and in tension with brain areas involved in focused attention and target detection: the default mode network. Theory characterizing the rTPJ based on the area’s purported role in reorienting may be falsely guided by the co-occurrence of two distinct effects in contiguous regions: activation of the supramarginal gyrus (SMG), associated with its functional role in target detection; and the transient release, during spatial reorienting, of suppression of the angular gyrus (AG) associated with focused attention. Findings based on meta-analysis and resting functional connectivity are presented which support this alternative account. We find distinct regions, possessing anti-correlated patterns of resting connectivity, associated with social reasoning (AG) and target detection (SMG) at the rTPJ. The locus for reorienting was spatially intermediate between the AG and SMG and showed a pattern of connectivity with similarities to social reasoning and target detection seeds. These findings highlight a general methodological concern for brain imaging. Given evidence that certain tasks not only activate some areas but also suppress activity in other areas, it is suggested that researchers need to distinguish two distinct putative mechanisms, either of which may produce an increase in activity in a brain area: functional engagement in the task versus release of suppression. (shrink)

This essay comprises two chapters from the first part of Bollnow’s book on moods, namely the second chapter on the concept of Stimmung and the third chapter on Stimmungen as the sustaining foundation of the soul. It argues that moods constitute the simplest and most original form in which human life comes to know itself. Moods are understood as a specific harmony between, first, the inner and outer world; second, the states of the body and the soul; and, third, the (...) individual faculties of the soul. Moods differ from emotions in the narrow sense, which are always intentionally directed towards a specific object, whereas moods do not have any specific object; they are states of being, structuring and coloring human existence as a whole. Hence, no system of moods is provided, but their extensive diversity is indicated. Furthermore, transient, unsteady, or “moody” moods are distinguished from persistent or basic moods. (shrink)

Decision theory explains weakness of will as the result of a conflict of incentives between different transient agents. In this framework, self-control can only be achieved by the I-now altering the incentives or choice-sets of future selves. There is no role for an extended agency over time. However, it is possible to extend game theory to allow multiple levels of agency. At the inter-personal level, theories of team reasoning allow teams to be agents, as well as individuals. I apply team (...) reasoning at the intra-personal level, taking the self as a team of transient agents over time. This allows agents to ask, not just “what should I-now do?’, but also ‘What should I, the person over time do?’, which may enable agents to achieve self-control. The resulting account is Aristotelian in flavour, as it involves reasoning schemata and perception, and it is compatible with some of the psychological findings about self-control. (shrink)

We contrast two theoretical positions on the relation between phenomenal and access consciousness. First, we discuss previous data supporting a mild Overflow position, according to which transient visual awareness can overflow report. These data are open to two interpretations: (i) observers transiently experience specific visual elements outside attentional focus without encoding them into working memory; (ii) no specific visual elements but only statistical summaries are experienced in such conditions. We present new data showing that under data-limited conditions observers cannot discriminate (...) a simple relation (same versus different) without discriminating the elements themselves and, based on additional computational considerations, we argue that this supports the first interpretation: summary statistics (same/different) are grounded on the transient experience of elements. Second, we examine recent data from a variant of ‘inattention blindness’ and argue that contrary to widespread assumptions, it provides further support for Overflow by highlighting another factor, ‘task relevance’, which affects the ability to conceptualize and report (but not experience) visual element. (shrink)

There are two conspicuous and inescapable features of this world in which time is real. One experiences a world in flux, a transient world in which things constantly come into existence, change and cease to be. One also experiences a stable world, one in which how things are at any given moment is permanent, unchangeable. Thus, there is transience and permanence. Yet these two features of the world seem incompatible. The primary purpose of this paper is to sketch a metaphysics (...) of time that embraces both features. Crucial to this undertaking is the notion of becoming, that is, coming into existence. I distinguish three distinct phenomena of becoming: temporal, absolute and atemporal. The last is the least familiar of these; it is the phenomenon of coming into existence outside of time. Although the idea that there are things that do not exist in time is not unfamiliar, it is largely taken for granted that if anything comes into existence, it must do so in time. (Indeed, I suspect many think that the idea of a thing coming to be outside of time is simply incoherent.) In this paper, I articulate and defend the notion of atemporal becoming. It is by means of this notion that one can develop a fully satisfactory metaphysics of time, one that honors both transience and permanence and finds for each its proper domain within the world. (shrink)

Merging of opinions results underwrite Bayesian rejoinders to complaints about the subjective nature of personal probability. Such results establish that sufficiently similar priors achieve consensus in the long run when fed the same increasing stream of evidence. Initial subjectivity, the line goes, is of mere transient significance, giving way to intersubjective agreement eventually. Here, we establish a merging result for sets of probability measures that are updated by Jeffrey conditioning. This generalizes a number of different merging results in the literature. (...) We also show that such sets converge to a shared, maximally informed opinion. Convergence to a maximally informed opinion is a (weak) Jeffrey conditioning analogue of Bayesian “convergence to the truth” for conditional probabilities. Finally, we demonstrate the philosophical significance of our study by detailing applications to the topics of dynamic coherence, imprecise probabilities, and probabilistic opinion pooling. (shrink)

This paper will argue that Hume's notion of the self in Book 2 of the Treatise seems subject to two constraints. First, it should be a succession of perceptions. Second, it should be durable in virtue of the roles that it plays with regard to pride and humility, as well as to normativity. However, I argue that these two constraints are in tension, since our perceptions are too transient to play these roles. I argue that this notion of self should (...) be characterized as a bundle of dispositions to our perceptions, such that these dispositions are durable and counterfactual-supporting. I argue that Hume confused his ‘philosophical’ notion of dispositions, as nothing above and beyond their effects, with the thicker notion of dispositions to which the passions respond—which explains his mistaken commitment to the durability constraint. (shrink)

Prerequisite to memory is a past distinct from present. Because wave evolution is both continuous and time-reversible, the undisturbed quantum system lacks a distinct past and therefore the possibility of memory. With the quantum transition, a reversibly evolving superposition of values yields to an irreversible emergence of definite values in a distinct and transient moment of time. The succession of such moments generates an irretrievable past and thus the possibility of memory. Bohm’s notion of implicate and explicate order provides a (...) conceptual basis for memory as a general feature of nature akin to gravity and electromagnetism. I propose that natural memory is an outcome of the continuity of implicate time in the context of discontinuous explicate time. Among the ramifications of natural memory are that laws of nature can propagate through time much like habits and that personal memory does not require neural information storage. (shrink)

Considering whether existence, i.e., being, is a thing might seem like the height of aimless metaphysical chin stroking. However, the issue—specifically, whether existence is a quality—is significant, bearing on how reality, this all-encompassing totality, is. On one view, reality at large is ontologically fixed, the sum total of things does not (and cannot) vary; on another view, reality is ontologically transient, the sum total of things varies. I first show that if existence is a thing, that reality is ontologically fixed (...) follows. So I consider whether existence is indeed a thing. I demonstrate that “it” could not be: existence is no existent. I then discuss what it is to exist, given existence is nothing at all. I maintain there are no grounds for the view that reality is ontologically fixed. I argue, from the irrefragable basis of temporal differentiation—the world going from thus…to as so—that reality is ontologically transient. I consider some objections to ontological transience and conclude by considering the key to understanding the overall structure in reality and what it reveals about how very inconstant all this is. (shrink)

This paper examines how time functions as an active subject in the works of Mark Doty and Edmund de Waal, mainly through their reflections on still life and material objects. Doty’s meditations on a still life painting and De Waal’s exploration of his family’s netsuke collection reveal an inversion of our typical understanding of time, where instead of us moving through time, time itself shapes, preserves, or erodes people, places, and things. By closely observing these objects—Doty’s “things of the world” (...) and De Waal’s family heirlooms—each author recognizes how time acts upon them, turning seemingly permanent elements into transient reflections. This study argues that, in both accounts, time is a subjugating force and a silent reminder of impermanence. In this way, the paper invites readers to adopt a “close-looking” perspective, recognizing time’s invisible yet profound impact on memory, materiality, and the passage of life itself. (shrink)

Several studies (e.g., Becklen & Cervone, 1983; Mack & Rock, 1998; Neisser & Becklen, 1975) have found that observers attending to a particular object or event often fail to report the presence of unexpected items. This has been interpreted as inattentional blindness (IB), a failure to see unattended items (Mack & Rock, 1998). Meanwhile, other studies (e.g., Pashler, 1988; Phillips, 1974; Rensink et al., 1997; Simons, 1996) have found that observers often fail to report the presence of large changes in (...) a display when these changes occur simultaneously with a transient such as an eye movement or flash of the display. This has been interpreted as change blindness (CB), a failure to see unattended changes (Rensink et al., 1997). In both cases there is a striking failure to report an object or event that would be quite visible under other circumstances. And in both cases there is a widespread (although not universal) belief that the underlying cause has to do with the absence of attention. The question then arises as to how these effects might be related. Is CB the same thing as IB? If not, what is the relation between them? And given that these phenomena deal with failures of subjective perception, what can they teach us about the nature of our visual experience? In particular, what can they teach us about the role played by visual attention? (shrink)

This is my contribution to a symposium on Berit Brogaard's book "Transient Truths" in which I criticize her treatment of various linguistic phenomena related to tense.

The developing body of empirical work on the "Gettier effect" indicates that, in general, the presence of a Gettier-type structure in a case makes participants less likely to attribute knowledge in that case. But is that a sufficient reason to diverge from a JTB theory of knowledge? I argue that considerations of good model selection, and worries about noise and overfitting, should lead us to consider that a live, open question. The Gettier effect is perhaps so transient, and so sensitive (...) to other, epistemologically-inappropriate factors, that it raises the question of whether it ought to be counted as something to include in our theories -- or as a piece of noise to be excluded from them. (shrink)

This paper examines possible converging points between Heidegger and Foucault on being and language. Both are concerned with the temporal movement of a transient event which, whether "presencing" as a thing-present or erupting-forth out of conflicting forces as a discursive configuration, becomes preserved as a subsistent "thing"--as a mode of being for Heidegger, as a mode of knowledge in relation to techniques of power for Foucault. This is accompanied with the claim to persist throughout its coming-to-be, transformations, and disappearing--an artificial (...) preservation accomplished in relation to language which names "that-which-cannot-be-named". (shrink)

Two of the main debates in philosophy of language concerning time and tense are the debate about the semantics of the tenses in the English language and the debate over whether propositions can be transiently true or false as opposed to always being eternally true or false. The latter quarrel is also known as the "temporalism–eternalism debate." Given standard semantics, the two debates are not logically independent, as we will see. Those who believe propositions are eternally true or false needn’t (...) treat the tenses as operators. Their opponents, on the other hand, appear to be committed to an operator theory of the tenses, given a standard semantic framework. In this chapter I will focus primarily on these two debates. (shrink)

Rensink, O’Regan, and Clark (1997) drew attention to the phenomenon of change blindness, in which even large changes can be difficult to notice if made during the appearance of motion transients elsewhere in the image. This article provides a sketch of the events that inspired that article as well as its subsequent impact on psychological science and on society at large.

Today’s ethics of privacy is largely dedicated to defending personal information from big data technologies. This essay goes in the other direction; it considers the struggle to be lost, and explores two strategies for living after privacy is gone. First, total exposure embraces privacy’s decline, and then contributes to the process with transparency. All personal information is shared without reservation. The resulting ethics is explored through a big data version of Robert Nozick’s Experience Machine thought experiment. Second, transient existence responds (...) to privacy’s loss by ceaselessly generating new personal identities, which translates into constantly producing temporarily unviolated private information. The ethics is explored through Gilles Deleuze’s metaphysics of difference applied in linguistic terms to the formation of the self. Comparing the exposure and transience alternatives leads to the conclusion that today’s big data reality splits the traditional ethical link between authenticity and freedom. Exposure provides authenticity, but negates human freedom. Transience provides freedom, but disdains authenticity. (shrink)

The thresholds of human observers detecting line targets improve significantly when the targets are presented in a spatial context of collinear inducing stimuli. This phenomenon is referred to as spatial facilitation, and may reflect the output of long-range interactions between cortical feature detectors. Spatial facilitation has thus far been observed with luminance-defined, achromatic stimuli on achromatic backgrounds. This study compares spatial facilitation with line targets and collinear, edge-like inducers defined by luminance contrast to spatial facilitation with targets and inducers defined (...) by color contrast. The results of a first experiment show that achromatic inducers facilitate the detection of achromatic targets on gray and colored backgrounds, but tend to suppress the detection of chromatic targets. Chromatic inducers facilitate the detection of chromatic targets on gray and colored backgrounds, but tend to suppress the detection of achromatic targets. Chromatic spatial facilitation appears to be strongest when inducers and background are isoluminant. The results of a second experiment show that spatial facilitation with chromatic targets and inducers requires a longer exposure duration of the inducers than spatial facilitation with achromatic targets and inducers, which is already fully effective at an inducer exposure of 30 ms only. The findings point towards two separate mechanisms for spatial facilitation with collinear form stimuli: one that operates in the domain of luminance, and one that operates in the domain of color contrast. These results are consistent with neural models of boundary and surface formation which suggest that achromatic and chromatic visual cues are represented on different cortical surface representations that are capable of selectively attracting attention. Multiple copies of these achromatic and chromatic surface representations exist corresponding to different ranges of perceived depth from an observer, and each can attract attention to itself. Color and contrast differences between inducing and test stimuli, and transient responses to inducing stimuli, can cause attention to shift across these surface representations in ways that sometimes enhance and sometimes interfere with target detection. (shrink)

A number of philosophers have defended the view that seemingly intellectually arrogant behaviours are epistemically beneficial. In this chapter I take issue with most of their conclusions. I argue, for example, that we should not expect steadfastness in one's belief in the face of contrary evidence nor overconfidence in one’s own abilities to promote better evaluation of the available evidence resulting in good-quality group-judgement. These features of individual thinkers are, on the contrary, likely to lead groups to end up in (...) stalemates and to polarise over issues. It is true that groups benefit from including members that, prior to discussion, hold diverse views. But disagreement benefits group judgement only when it is transient, rather than entrenched. That is, groups reach better quality conclusions when a number of diverse opinions are disseminated and evaluated fairly before reaching a consensus. If this is right, it would seem that individual qualities, such as open-mindedness and even-handedness about the epistemic value of opinions other than one's own, rather than steadfastness or overconfidence are conducive to better quality group judgement. (shrink)

This essay hypothesizes that the Universe contains a self-reproducing neural network of Black Holes with computational abilities—i.e., the Universe can “think”! It then rephrases the Final Anthropic Principle to state: “Intelligent information-processing must come into existence in each new Universe to assure the birth of intelligent successor universes”. Continued research into the theory of Early Universe and Black Hole information storage, processing and retrieval is recommended, as are observational searches for time-correlated electromagnetic and gravitational wave emission patterns from widely separated (...) Black Hole transient events indicative of the existence of a universal inter-Black Hole faster-than-light communications network. (shrink)

Technology scholars and journalists have recently called attention to digital platforms’ and devices’ ability to influence users based on their present moods, stress level, hunger, and other transient features. For them, such influence based on users’ present status – what the chapter calls “real-time profiling” – is not only a clear form of wrongful manipulation but also online manipulation’s future. The chapter aims to explain what makes real-time profiling wrong (when wrong) and discusses problems associated with its regulation. After explaining (...) what real-time profiling consists in and showing that it can be presumed to be a form of manipulation, the chapter argues that real-time profiling is wrong both because the profiler psychologically hijacks profiled subjects and because it works as a gateway to further wrongs. Towards the end, the chapter discusses some implications of the proposed account for the legal regulation of online manipulative technologies like real-time profiling. It is argued that existing legal frameworks are not fine-grained enough to deal with the wrongs associated with real-time profiling and related forms of online manipulation. (shrink)

Writer, book and reader, without writer and writings wouldn’t have been a reader. Hence, there wouldn’t have been criticism. The basis of human intellectual criticism depends on three basic elements: The writer, the book, and the reader. Criticism was essentially linked with the discovery of writing. Criticism as an idea is basically linked with human consciousness. Maturity, writing has merely added a new dimension to it namely criticism and synthesis, in which literature and philosophy has contributed greatly, despite the differences (...) between the two subject. Philosophy does not define one method for itself , for there are many trends and methods. Despite the differences in philosophers’ views on methods, there is a sort of unanimous of agreement among them on the method of analysis and synthesis. The general feature which characterizes philosophers, is their reliance on the proofs of the ancestors’ . Every philosopher uses the ancestors’ proof to criticize the theory of his predications before attempting to build new theory. -/- Criticism in general is comments on article. The critic should rely on all materials and use all the tools available to be able to cover the criticized article thoroughly. Thus, the history of philosophy is a history of criticism relying on the theories of the philosophers who preceded the new theory, whose theory is just an expression of communication and development, because he did not start from nothing. Each philosophers starts a critical argument of his predecessors’ views, try to benefit from them before announcing his views, which he believes there is something new about it. -/- Thus, philosophy critics were always ready to defend their critical views although despite the differences in their purpose. In this book I will try to review and analyze the status of philosophical criticisms and then try to define the points of agreement and disagreement between some of philosophical schools. -/- Therefore, the first chapter of this book deals with philosophical criticism and sensory perception of Plato, while the second chapter deals with criticism and existence. The subject of the third chapter is critical transformations in Physics and Metaphysics, undermining the transient truth, the entity of women in the mirror of critical mind, then criticism of science. -/- This book, along with other books , contributes to providing the readers with additional ideas of philosophical criticisms . (shrink)

This article describes a case of a teenager with early complex trauma due to chronic domestic violence. Cannabis use triggered auditory hallucinations, after which the teenager was diagnosed with an acute schizophrenia-like psychotic disorder. Antipsychotic medication did not fully resolve symptoms. Eventually the teenager chose to self-medicate with LSD in order to resolve a suicidal condition. The teenager carried out six unsupervised LSD sessions, followed by an extended period of almost daily use of inhaled low-dose DMT. Psychotic symptoms were mostly (...) resolved after approximately one year. Subsequent cannabis use caused a transient relapse. -/- While his psychosis may have been due to cannabis use in the presence of a genetic predisposition, LSD and DMT did not promote psychotic symptoms in this case, and resolved the suicidal condition in one session. Additional high-dose LSD sessions and low-dose DMT sessions appeared to resolve the symptoms related to the early complex trauma. Alternatively, if psychosis is understood as a massive defense system resulting from early complex trauma, and if his psychotic symptoms were partially due to such trauma, psychedelics appeared to transcend this defense system, providing access to traumatic memories in order to allow for an integrative treatment effect. -/- Information was acquired from medical record excerpts provided by the patient, a semi-structured retrospective video interview, and follow-up interviews a year later. The present case suggests a need for further studies on the relationship between psychedelics and psychotic disorders, the feasibility of supervised vs unsupervised settings for various situations, and alternative therapeutic models for utilizing the hyperaware-hypersensitive state induced by psychedelics. With regard to self-treatment, a harm reduction approach should be adopted. Low-risk psycholytic self-treatment protocols could be developed for future use in public health care systems. (shrink)

The explanation of nature in theoretical terms was first postulated and initiated by Ancient Greek philosophers. With the rise of monotheistic religions, however, curiosity about our transient world was widely regarded as contributing nothing to salvation. There was a decline in natural philosophy, which lasted for several centuries and was then reversed both in Islamic philosophy and in Christian theology in the Middle Ages. At this point, the "Book of Nature" was recognized as a complement to the Book of Revelation. (...) Originally, Aristotelian philosophy played the leading part in this process, but only after Aristotelian physics was substituted by experimental mathematical mechanics did it become possible for modern science to develop. General laws of physics form the basis of the explanation of events in space and time, including life processes. However, modern science has also revealed its own limitations. The scope and limits of scientific knowledge allows for different philosophical, cultural and religious interpretations of human beings and the universe. The history of science demonstrates erratic and persistent developments, but the long-term retrospective view discredits extreme forms of relativism and structuralism. Science appears as a construct of the human mind, and yet it is capable of generating valid explanations of nature. In the book more attention than usual is given to Cusanus (Nikolas de Cusa). -/- . (shrink)

Ancient Greek philosophers were the first to postulate the possibility of explaining nature in theoretical terms and to initiate attempts at this. With the rise of monotheistic religions of revelation claiming supremacy over human reason and envisaging a new world to come, studies of the natural order of the transient world were widely considered undesirable. Later, in the Middle Ages, the desire for human understanding of nature in terms of reason was revived. This article is concerned with the fundamental reversal (...) of attitudes, from “undesirable” to “desirable”, that eventually led into the foundations of modern science. One of the earliest, most ingenious and most interesting personalities involved was Eriugena, a theologian at the Court of Charles the Bald in the 9th century. Though understanding what we call nature is only one of the several aspects of his theological work, his line of thought implies a turn into a pro-scientific direction: the natural order is to be understood in abstract terms of ‘primordial causes’; understanding nature is considered to be the will of God; man encompasses the whole of creation in a physical as well as a mental sense. Basically similar ideas on the reconciliation of scientific rationality and monotheistic religions of revelation were conceived, independently and nearly simultaneously, by the Arab philosopher al-Kindi in Bagdad. Eriugena was more outspoken in his claim that reason is superior to authority. This claim is implicit in the thought of Nicholas of Cusa with his emphasis on human mental creativity as the image of God’s creativity; and it is the keynote of Galileo’s ‘Letter to the Grand Duchess Christina’ some 800 years later, the manifesto expressing basic attitudes of modern science. -/- This article in English is based on the monography (in German): A. Gierer “Eriugena, al-Kindi, Nikolaus von Kues - Protagonisten einer wissenschaftsfreundlichen Wende im philosophischen und theologischen Denken”, Acta Historica Leopoldina 29 (1999), Barth Verlag in MVH Verlage Heidelberg, ISBN: 3-335-00652-6, which is also available online on this server. -/- -/- . (shrink)

Ancient Greek philosophers were the first to postulate the possibility of explaining nature in theoretical terms and to initiate attempts at this. With the rise of monotheistic religions of revelation claiming supremacy over human reason and envisaging a new world to come, studies of the natural order of the transient world were widely considered undesirable. Later, in the Middle Ages, the desire for human understanding of nature in terms of reason was revived. This article is concerned with the fundamental reversal (...) of attitudes, from "undesirable" to "desirable", that eventually led into the foundations of modern science. One of the earliest, most ingenious and most interesting personalities involved was Eriugena, a theologian at the Court of Charles the Bald in the 9th century. Though understanding what we call nature is only one of the several aspects of his philosophical work, his line of thought implies a turn into a pro-scientific direction: the natural order is to be understood in abstract terms of "primordial causes"; understanding nature is considered to be the will of God; man encompasses the whole of creation in a physical as well as a mental sense. Basically similar ideas on the reconciliation of scientific rationality and monotheistic religions of revelation were conceived, independently and nearly simultaneously, by the Arab philosopher al-Kindi in Bagdad. Eriugena was more outspoken in his claim that reason is superior to authority. This claim is implicit in the thought of Nicholas of Cusa with his emphasis on human mental creativity as the image of God's creativity; and it is the keynote of Galileo's "Letter to the Grand Duchess Christina" some 800 years later, the manifesto expressing basic attitudes of modern science. (shrink)

Given the hard problem of consciousness, there are no brain electrophysiological correlates of the subjective experience (the felt quality of redness or the redness of red, the experience of dark and light, the quality of depth in a visual field, the sound of a clarinet, the smell of mothball, bodily sensations from pains to orgasms, mental images that are conjured up internally, the felt quality of emotion, the experience of a stream of conscious thought, or the phenomenology of thought). However, (...) there are occipital and left temporal brain electrophysiological correlates of the subjective experience. Notwithstanding, as an evoked signal, the change in event-related brain potential phase (frequency is the change in phase over time) is instantaneous, that is, the frequency will transiently be infinite: a transient peak in frequency (positive or negative), if any, is instantaneous in electroencephalogram averaging or filtering that the event-related brain potentials required and the underlying structure of the event-related brain potentials in the frequency domain cannot be accounted for, for example, by the Wavelet Transform or the Fast Fourier Transform analysis, because they require that frequency be derived by convolution rather than by differentiation. However, as I show, one suitable method for analysing the instantaneous change in event-related brain potential phase and accounting for a transient peak in frequency (positive or negative), if any, in the underlying structure of the event-related brain potentials is the Empirical Mode Decomposition with post-processing Ensemble Empirical Mode Decomposition. (shrink)

Abstract: -/- The Immortality and the Fear of Losing Loved Ones argument addresses a common objection to the pursuit of immortality: the concern of outliving loved ones and the emotional toll it may carry. By drawing parallels to human relationships with pets—relationships often characterized by profound emotional bonds despite the knowledge of their temporary nature—this argument suggests that the fear of outliving others need not deter the desire for immortality. -/- The argument posits that humans regularly form meaningful, fulfilling relationships (...) even when aware of their temporary nature, as with pets whose shorter lifespans are universally accepted. It concludes that individuals can continue to find meaning and fulfillment in relationships, even if they eventually outlive others, and that the transient nature of relationships should not prevent one from pursuing eternal life. This perspective offers a nuanced view on immortality, suggesting that the potential for new connections and experiences can provide ongoing value, despite the inevitable loss of loved ones. (shrink)

Ketamine is a well-known and widely available general anesthetic from the 1960s that, in sub-anesthetic doses, has been adopted in a limited manner for the treatment of acute suicidality and treatment-resistant depression. Its short onset time and short duration of action make it feasible for use at outpatient clinics. In the US, it has a long history of off-label use and was officially approved for depression treatment in 2019. In Finland, it has been administered to selected hospitalized patients in the (...) public healthcare system since 2010 and became available at a private outpatient clinic very recently. In Norway, it has been administered off-label at a private clinic for approximately 500 patients since mid-2010s and at a public clinic for approximately 300 patients since 2020, with plans on opening more clinics in 2024. In the US, the treatment has been administered to hundreds of thousands of patients. -/- The retrospective ethnographic inquiry part of this study features a Finnish woman in her twenties who suffered from treatment-resistant depression, rooted in her insecure childhood and having been bullied at school, as well as income insecurity and excessive workload in adulthood. Eventually, she was violently raped, which induced an obvious post-traumatic stress disorder and exacerbated her depression, incapacitating her. In the course of approximately five years, she was prescribed ten different anti-depressive medications and seventeen other medications, including various antipsychotic medications and lithium. These failed to provide an anti-depressive effect but resulted in 'massive' adverse effects instead, including 60% weight gain and psychotic hallucinations. Eventually, esketamine spray treatment at a private outpatient clinic resolved her depression in a single session. A weekly re-administration process was ongoing. -/- In this case, repeated esketamine administration alleviated depression by producing accumulating corrective emotional experiences without the need to re-experience previous traumatizing events. In a few months to a year, the transient but accumulating anti-depressive effect typically leads to the resolution of depression in most cases, if the patients' living conditions no longer constantly re-traumatize them. It is necessary to adopt ketamine more widely as an emergency measure while more effective, non-addictive alternatives and complements are prepared for adoption. The cost of this specific pilot program implementation was unscalable, but costs can be reduced by approximately 90% by modifying the implementation details. Ketamine and its more effective alternative, 5-MeO-DMT, can serve a major role in facilitating a rebirth of public and private mental healthcare systems, with treatment efficacy multiplied and treatment costs simultaneously reduced. (shrink)

The main target of this paper is to control the speed of DC motor by comparing the actual and the desired speed set point. The DC motor is designed using Fuzzy logic and MPC controllers. The comparison is made between the proposed controllers for the control target speed of the DC motor using square and white noise desired input signals with the help of Matlab/Simulink software. It has been realized that the design based on the fuzzy logic controller track the (...) set pointwith the best steady state and transient system behavior than the design with MPC controller. Finally, the comparative simulation result prove the effectiveness of the DC motor with fuzzy logic controller. (shrink)

: COVID-19 has proliferated over the earth, exposing mankind at risk. The assets of the world's most powerful economies are at stake due to the disease's high infectivity and contagiousness. The capacity of machine learning algorithms can estimate the amount of future COVID-19 cases, which is now considered a possible threat to civilization. Five conventional measuring models, notably LR, LASSO, SVM, ES, and LSTM, were utilised in this work to examine COVID-19's undermining variables. Each model contains three sorts of expectations: (...) the number of newly contaminated cases, the number of passings, and the number of recoveries. However, it is hard to anticipate the patients' real outcomes. To address the issue, a suggested approach based on long transient memory (LSTM) forecasts the number of COVID-19 cases in the next 10 days as well as the impact of preventative measures such as social isolation and lockdown on COVID-19 spread. (shrink)

Against the background of revolutionary digital technologies, mobile learning and the crisis of conventional paradigms in mass societies, the present study shows how innovative and multidisciplinary research capable of both observing and interpreting reality as well as consolidating a pedagogical model open to intercultural dialogue with faith and ethics will allow different cultures to re-appropriate the scientific, pedagogic, ethical and linguistic methodologies necessary for the formation of the ‘human being’. The post-modern condition of the ‘liquid society’, where only transient values (...) are given, with the consequence of uncertainty and dissatisfaction, is the right time to return to the true moral values, i.e. those described by the classical philosophy and the Christian religion that fully realize the human being. This inspiration enables Pedagogy to overcome the uncertainties that afflict subjects in education; overcome the absence of languages and shared ethics; overcome the paroxysmal defense of freedom of thought and action; respond to the lack of model teachers who can have a positive influence on their students; discourage marked and more widespread individualism. (shrink)

Saturated free fatty acids-induced hepatocyte lipoapoptosis plays a pivotal role in non-alcoholic steatohepatitis. Theactivation of endoplasmic reticulum (ER) stress isinvolved in hepatocyte lipoapoptosis induced by thesaturated free fatty acidpalmitate (PA). However, the underlying mechanismsof the role of ER stress in hepatocyte lipoapoptosis remain largely unclear.In this study, we showed that PA and tunicamycin (Tun), a classic ER stress inducer, resulted in differential activation of ERstress pathways. Our data revealed that PA inducedchronic and persistent ER stress response, but Tuninduced acute and (...) transientER stress response. Compared with Tun treatment, PAinduced much lower glucose-regulated protein 78 (GRP78), a centralregulator of ER homeostasis, accumulation. It is noteworthy that GRP78 over-expression not only inhibited PA-induced ERstress but also decreased PA-induced apoptosis. Taken together, our data suggest that the differentialactivation of ER stresssignal plays an important role in PA-induced hepatocyte lipoapoptosis. More detailed studies on the mechanisms of PA inrepressing the accumulation of GRP78 will contribute to the understanding of molecular mechanisms of lipoapoptosis. (shrink)

Saturated free fatty acids-induced hepatocyte lipoapoptosis plays a pivotal role in non-alcoholic steatohepatitis. Theactivation of endoplasmic reticulum (ER) stress isinvolved in hepatocyte lipoapoptosis induced by thesaturated free fatty acidpalmitate (PA). However, the underlying mechanismsof the role of ER stress in hepatocyte lipoapoptosis remain largely unclear.In this study, we showed that PA and tunicamycin (Tun), a classic ER stress inducer, resulted in differential activation of ERstress pathways. Our data revealed that PA inducedchronic and persistent ER stress response, but Tuninduced acute and (...) transientER stress response. (shrink)

Following the previous relevant works [1]-[3], a scaling analysis is performed to derive a set of scaling criteria which were thought to be suitable for reproducing the major thermal-hydraulic phenomena in a scaled-down CANDU moderator tank similar to that in a prototype power plant during a full power steady state condition. The objective of building a scaled-down moderator tank is to generate the experimental data necessary to validate the computer codes which are used to analyze the accident analysis of CANDU-6 (...) plants. The major variables of interests in this paper are moderator flow velocity and temperature of the moderator which is D2O inside the moderator tank during a steady state and transient conditions. The reason is that the local subcooling of the moderator is found to be a critical parameter determining whether the stable film boiling can sustain on the outer surface of the calandria tube if the contact of overheated pressure tube and cold calandria tube should occur due to pressure tube ballooning during LBLOCA with ECC injection failure [4]. The key phenomena involved include the inlet jet development and impingement, buoyancy force driven by the moderator temperature gradient caused by non-uniform direct heating of the moderator, and the pressure drop due to viscous friction of the flow across the calandria tube array. In this paper, the previous researches are reviewed, some concerns or potential problems associated with them implied by comparing CFD analyses results between the CANDU-6 moderator tank and 1/4 scaled-down test facility are described, and as a way to examine the assumption of the scaling analysis is true an order-of-magnitude analyses are performed. Based on the results of these analyses the assumption of neglecting and terms cannot be justified for the power of 0.5 MW and 1.566 MW for the 1/4 scaled-down facility. Further investigation is thought to be necessary to confirm this result, i.e. if the scaling of the previous work1 is justifiable by some other independent analyses. (shrink)