Precision medicine and molecular systems medicine (MSM) are highly utilized and successful approaches to improve understanding, diagnosis, and treatment of many diseases from bench-to-bedside. Especially in the COVID-19 pandemic, molecular techniques and biotechnological innovation have proven to be of utmost importance for rapid developments in disease diagnostics and treatment, including DNA and RNA sequencing technology, treatment with drugs and natural products and vaccine development. The COVID-19 crisis, however, has also demonstrated the need for systemic thinking and transdisciplinarity and the limits (...) of MSM: the neglect of the bio-psycho-social systemic nature of humans and their context as the object of individual therapeutic and population-oriented interventions. COVID-19 illustrates how a medical problem requires a transdisciplinary approach in epidemiology, pathology, internal medicine, public health, environmental medicine, and socio-economic modeling. Regarding the need for conceptual integration of these different kinds of knowledge we suggest the application of general system theory (GST). This approach endorses an organism-centered view on health and disease, which according to Ludwig von Bertalanffy who was the founder of GST, we call Organismal Systems Medicine (OSM). We argue that systems science offers wider applications in the field of pathology and can contribute to an integrative systems medicine by (i) integration of evidence across functional and structural differentially scaled subsystems, (ii) conceptualization of complex multilevel systems, and (iii) suggesting mechanisms and non-linear relationships underlying the observed phenomena. We underline these points with a proposal on multi-level systems pathology including neurophysiology, endocrinology, immune system, genetics, and general metabolism. An integration of these areas is necessary to understand excess mortality rates and polypharmacological treatments. In the pandemic era this multi-level systems pathology is most important to assess potential vaccines, their effectiveness, short-, and long-time adverse effects. We further argue that these conceptual frameworks are not only valid in the COVID-19 era but also important to be integrated in a medicinal curriculum. (shrink)

Indem dieser Band sich auf das Verhältnis von Naturerkennen und Natursein konzentriert, thematisiert er einen wesentlichen Ausschnitt aus dem weiten Spektrum von Böhmes philosophischer Arbeit. Um die Naturthematik möglichst breit zu entfalten und für Querverbindungen offenzuhalten, ist der vorliegende Band in drei Abschnitte gegliedert. Im ersten Abschnitt stehen Charakter und Reichweite der wissenschaftlichen Erkenntnis von Natur im Mittelpunkt. Der zweite Teil des Bandes stellt alternative Perspektiven auf Natur vor. Im dritten Teil schließlich stehen der Mensch und sein Verhältnis zu sich (...) selbst im Mittelpunkt der Untersuchungen. Inhaltsverzeichnis Krohn, Wolfgang: Wissenschaftsentwicklung zwischen Dezentrierung und Dekonstruktion. Stehr, Nico: Von den Grenzen der Macht wissenschaftlicher Erkenntnis. Schäfer, Wolf: Zweifel am Ende des Baconschen Zeitalters. Kamper, Dietmar: Wissen ist Ohnmacht. Macht ist Unwissen. Gamm, der Technik. Janich, Peter: Zeit und Natur. Kimmerle, Heinz: »Es ist Zeit, daß es Zeit wird«. Wie kann Zeit Zeit werden? Schiemann, Gregor: Natur auf dem Rückzug. Zur Relevanz der aristotelischen Unterscheidung von Natur und Technik. Hauskeller, Michael: Ist Schönheit eine Atmosphäre?. Zur Bestimmung des landschaftlich Schönen. Schmitz, Hermann: Situationen und Atmosphären. Zur Ästhetik und Onthologie bei Gernot Böhme. Rehmann-Sutter, Christoph: Über Relationalität. Was ist das »Ökologische« in der Naturästhetik? Meyer-Abich, Klaus Michael: Erinnerung an die natürliche Mitwelt. Andreas-Griesebach, Manon: Idee plus Erfahrung. Goethes Begründung eines neuen Typs von Naturwissenschaft. Engelhardt, Dietrich von: Madame de Stael über Naturphilosophie, Naturwissenschaft und Medizin in De l'Allemagne. Deneke, Michael: Schramm, Engelbert: »Soziale Naturwissenschaft«. Zwischen Sozialwissenschaften und Naturwissenschaften. Böhme, Hartmut: Enthüllen und Verhüllen des Körpers. Biblische, mythische und künstlerische Deutungen des Nackten. Lippe, Rudolf zur: Eine Logik des gestischen Wissens. Müller, Rudolf Wolfgang: Gernot Böhme - Anima naturaliter japonica. Hoffmann, Gisbert: Das menschliche Sein als mediales. Martens, Ekkehard: »Natürlich« denken?. Heideggers Pseudosokratismus als Irrationalismus. Fleischer, Helmut: Naturalität ohne Naturalismus. Zum lebensweltlichen Fundus jeder höheren Erkenntnis-Artistik. Gerhard: Technik als Medium. Grundlinien einer Philosophie. (shrink)

In this paper, we offer reasons to justify the explanatory credentials of dynamical modeling in the context of the metaplasticity thesis, located within a larger grouping of views known as 4E Cognition. Our focus is on showing that dynamicism is consistent with interventionism, and therefore with a difference-making account at the scale of system topologies that makes sui generis explanatory differences to the overall behavior of a cognitive system. In so doing, we provide a general overview of the interventionist approach. (...) We then argue that recent mechanistic attempts at reducing dynamical modeling to a merely descriptive enterprise fail given that the explanatory standard in dynamical modeling can be shown to rest on interventionism. We conclude that dynamical modeling captures features of nested and developmentally plastic cognitive systems that cannot be explained by appeal to underlying mechanisms alone. (shrink)

Aus dem vielfältigen Werk von Hermann von Helmholtz versammelt diese Ausgabe die im engeren Sinne philosophischen Abhandlungen, vor allem zur Wissenschaftsphilosophie und Erkenntnistheorie, sowie Vorträge und Reden, bei denen der Autor seine Ausnahmestellung im Wissenschaftsbetrieb nutzte, um die Wissenschaften und ihre Institutionen in der bestehenden Form zu repräsentieren und zu begründen. Ein Philosoph wollte Helmholtz nicht sein, aber er legte der philosophischen Reflexion wissenschaftlicher Erkenntnis und wissenschaftlichen Handelns große Bedeutung bei. Vor allem bezog er, in der Regel ausgehend von (...) seinen fachwissenschaftlichen Forschungen, in den verschiedensten Kontexten zu erkenntnistheoretischen und methodologischen Problemen der Wissenschaften Stellung. Bereits »Ueber die Erhaltung der Kraft« (1847) lässt erkennen, wie verwoben naturwissenschaftliche Grundlagenforschung und philosophische Grundlagenreflexion in seinem Werk sind. Die aus den frühen sinnesphysiologischen Forschungen hervorgegangene empiristische Wahrnehmungslehre trug ihm den Ruf ein, ein maßgeblicher Vertreter des Neukantianismus zu sein. Spätere Arbeiten v.a. zur Geometrie und Arithmetik – das zeigt die vorliegende Ausgabe – stellen jedoch eine radikale Absage an den konstitutiven Kern des Kantianismus (nämlich die Existenz synthetischer Urteile a priori) dar. Helmholtz’ philosophische Beiträge sind bisher in ihrer Vollständigkeit nicht annähernd so gut zugänglich wie sein naturwissenschaftliches Werk. Die Ausgabe enthält außerdem bibliographische Vorberichte zur Einordnung, detaillierte Namens- und Sachregister sowie mit 575 Einträgen für den Zeitraum zwischen 1842 und 2012 die erste umfassende Bibliographie von Helmholtz verfasster Werke überhaupt. »Ich glaube, dass der Philosophie nur wieder aufzuhelfen ist, wenn sie sich mit Ernst und Eifer der Untersuchung der Erkenntnissprocesse und der wissenschaftlichen Methode zuwendet. Da hat sie eine wirkliche und berechtigte Aufgabe.« Helmholtz in einem Brief um 1875. (shrink)

Historical Cognitive Science I am lucky to strike three reviewers who extract so clearly my book's spirit as well as its substance. They all both accept and act on my central methodological assumption; that detailed historical research, and consideration of difficult contemporary questions about cognition and culture, can be mutually illuminating. It's gratifying to find many themes which recur in different contexts throughout _Philosophy and Memory_ _Traces_ so well articulated here. The reviews catch my desires to interweave discussion of cognitive (...) theories of memory with moral questions of psychological control and self-mastery, to evoke the virtues and the pleasures of strange, baroque beliefs about fickle 'animal spirits' coursing through the nerves and the brain, to demonstrate that mechanistic explanation (even in its blunt old Cartesian form) can acknowledge complexity, and to develop scientific conceptions of dynamic memory traces and representations which can survive uncharitable philosophical criticism. The book's insistent interdisciplinarity is just an inchoate quest to acknowledge the daunting variety of the phenomena: remembering is both natural and cultural, and is studied by narrative theorists as well as neurobiologists, by physicists as well as psychologists. By fusing the rangy detail of a history of early modern neurophysiology with the committed, even gullible fervor of a defence of 'new connectionist' cognitive science, I wanted to pull out the carpet from all those who are happy to let 'scientific' and 'cultural' approaches to the mind run along independently. Once this general project is given space, as it is by all three reviewers, we can get down to specifics. (shrink)

Review of THEO C. MEYERING, Historical Roots of Cognitive Science : The Rise of a Cognitive Theory of Perception from Antiquity to the Nineteenth Century. Boston: Kluwer, xix + 250 pp. $69.00. Examines the author's interpretation of Aristotelian theories of perceptual cognition, early modern theories, and Helmholtz's theory.

Externalist theories of justification create the possibility of cases in which everything appears to one relevantly similar with respect to two propositions, yet one proposition is justified while the other is not. Internalists find this difficult to accept, because it seems irrational in such a case to affirm one proposition and not the other. The underlying internalist intuition supports a specific internalist theory, Phenomenal Conservatism, on which epistemic justification is conferred by appearances.

Jenny Saville is a leading contemporary painter of female nudes. This paper explores her work in light of theories of gender and embodied agency. Recent work on the phenomenology of embodiment draws a distinction between the body image and the body schema. The body image is your representation of your own body, including your visual image of it and your emotional attitudes towards it. The body schema is comprised of your proprioceptive knowledge, your corporeally encoded memories, and your corporeal proficiency (...) with respect to various environments and activities. Saville is concerned with body image issues, and I discuss how she reconfigures representational practices with respect to feminine body images. However, the most exciting potential for feminist analysis of the state of the female nude derives from the concept of the body schema, for this concept endows the human body with subjectivity and agency. My key question, then, is by what pictorial means and to what extent Saville succeeds in representing agentic womanhood. I argue that interpreting Saville’s paintings from the standpoint of the body schema demonstrates the radicality of her remaking of the female nude and the rapport between her imagery and feminist values. (shrink)

Meine Rekonstruktion von HeImholtz' Begründung der Energieerhaltung beabsichtigt, vor allem das Verhältnis von empirischen und nichtempirischen Elementen aufzuklären. Als erstes möchte ich zeigen, worin die nichtempirischen Elemente bestehen und dass Helmholtz bereits in der Einleitung, wo der selbständige Energiebegriff noch nicht entwickelt ist, an entscheidenden Stellen auf die wissenschaftliche Erfahrung Bezug nimmt. Im Gegensatz zur Transzendentalphilosophie macht Helmholtz die Geltungsbedingungen seines Mechanismus von zukünftigen empirischen Ergebnissen der Wissenschaft abhängig. Er gibt seinem Mechanismus in diesem Zusammenhang eine hypothetische Geltung, an deren (...) bloß vorübergehenden Charakter er aber bemerkenswerterweise keinen Zweifel hegt. (1.) Im zweiten Teil gehe ich der Frage nach, in welchem Maß die mit großer Siegesgewissheit vorgetragene mechanistische Begründung in die Formulierungen des Erhaltungssatzes Eingang findet. Helmholtz verwendet mehrere Energiebegriffe. Haben diese insgesamt oder nur teilweise einen von speziellen naturphilosophischen Annahmen unabhängigen Status? Auf welche Teile der Schrift hätte sich ein Wissenschaftler im vergangenen Jahrhundert stützen können, weIcher von der Energieerhaltung, nicht aber von Helrnholtz' Mechanismus überzeugt gewesen wäre? (2.). (shrink)

While philosophers hold that it is patently absurd to blame robots or hold them morally responsible [1], a series of recent empirical studies suggest that people do ascribe blame to AI systems and robots in certain contexts [2]. This is disconcerting: Blame might be shifted from the owners, users or designers of AI systems to the systems themselves, leading to the diminished accountability of the responsible human agents [3]. In this paper, we explore one of the potential underlying reasons for (...) robot blame, namely the folk's willingness to ascribe inculpating mental states or "mens rea" to robots. In a vignette-based experiment (N=513), we presented participants with a situation in which an agent knowingly runs the risk of bringing about substantial harm. We manipulated agent type (human v. group agent v. AI-driven robot) and outcome (neutral v. bad), and measured both moral judgment (wrongness of the action and blameworthiness of the agent) and mental states attributed to the agent (recklessness and the desire to inflict harm). We found that (i) judgments of wrongness and blame were relatively similar across agent types, possibly because (ii) attributions of mental states were, as suspected, similar across agent types. This raised the question - also explored in the experiment - whether people attribute knowledge and desire to robots in a merely metaphorical way (e.g., the robot "knew" rather than really knew). However, (iii), according to our data people were unwilling to downgrade to mens rea in a merely metaphorical sense when given the chance. Finally, (iv), we report a surprising and novel finding, which we call the inverse outcome effect on robot blame: People were less willing to blame artificial agents for bad outcomes than for neutral outcomes. This suggests that they are implicitly aware of the dangers of overattributing blame to robots when harm comes to pass, such as inappropriately letting the responsible human agent off the moral hook. (shrink)

Can an ugly experiment be a good experiment? Philosophers have identified many beautiful experiments and explored ways in which their beauty might be connected to their epistemic value. In contrast, the present chapter seeks out (and celebrates) ugly experiments. Among the ugliest are those being designed by AI algorithms. Interestingly, in the contexts where such experiments tend to be deployed, low aesthetic value correlates with high epistemic value. In other words, ugly experiments can be good. Given this, we should conclude (...) that beauty is not generally necessary or sufficient for epistemic value, and increasing beauty will not generally tend to increase epistemic value. (shrink)

Imagination is necessary for scientific practice, yet there are no in vivo sociological studies on the ways that imagination is taught, thought of, or evaluated by scientists. This article begins to remedy this by presenting the results of a qualitative study performed on two systems biology laboratories. I found that the more advanced a participant was in their scientific career, the more they valued imagination. Further, positive attitudes toward imagination were primarily due to the perceived role of imagination in problem-solving. (...) But not all problem-solving episodes involved clear appeals to imagination, only maximally specific problems did. This pattern is explained by the presence of an implicit norm governing imagination use in the two labs: only use imagination on maximally specific problems, and only when all other available methods have failed. This norm was confirmed by the participants, and I argue that it has epistemological reasons in its favour. I also found that its strength varies inversely with career stage, such that more advanced scientists do (and should) occasionally bring their imaginations to bear on more general problems. A story about scientific pedagogy explains the trend away from (and back to) imagination over the course of a scientific career. Finally, some positive recommendations are given for a more imagination-friendly scientific pedagogy. (shrink)

Drawing on work from Marina Sbisà’s “Ideology and the Persuasive Use of Presupposition” (1999), Rae Langton has developed a powerful account of the subtle mechanisms through which hate speech and propaganda spread. However, this model has a serious limitation: it focuses too strongly on individual speech acts isolated from their wider context, rendering its applicability to a broader range of cases suspect. In this chapter, I consider the limits of presupposition accommodation to clarify the audience’s role in helping hate speakers, (...) and claim the necessary mechanisms are much more active and social than Langton suggests, with effects not capturable in the analysis of isolated speech acts. I revisit Sbisà’s work on presupposition and develop an alternative model that (1) improves upon the Langtonian model for explaining the power of hate propaganda, and (2) is more in line with Sbisà’s original approach to ideology and the normative aspects of presupposition. (shrink)

In this paper I propose to shed new light on the role of feeling in Kant’s psychology of moral motivation by focusing on the concept of an incentive (Triebfeder), a term he borrowed from one of his most important rationalist predecessors, Alexander Gottlieb Baumgarten. I argue that, similar to Baumgarten, Kant understands an incentive to refer to the ground of desire and that feelings function as a specific kind of ground within Kant’s psychology of moral action, namely as the ‘impelling (...) cause’ of desire. I claim that this interpretation has several advantages over the alternatives currently on offer in the literature. (shrink)

In this paper I explore Phyllis Rooney’s 2003 chapter, “Feminist Epistemology and Naturalized Epistemology: An Uneasy Alliance,” taking guidance from her critique of naturalized epistemology in pursuing my own analysis of another uneasy alliance: that between feminist epistemology and social epistemology. Investigating some of the background assumptions at work in prominent conceptions of social epistemology, I consider recent analyses of "epistemic bubbles" to ask how closely such analyses are aligned with ongoing research in feminist epistemology. I argue that critical feminist (...) insights in political philosophy are called for here, especially those that focus on multiple politically salient relationships and also emphasize practices of personal transformation as inseparably bound up with broader movements for social transformation. Insofar as feminist epistemology continues to carry another world in its heart, I argue that it will continue to rest uneasily with any effort to align it with—let alone subsume it within—the still emerging field of social epistemology. (shrink)

Right after Philo’s about-face in Part 12 of the Dialogues, he gives an argument that the dispute between the theist and the atheist is merely verbal. Since everything is at least a little like everything else, the atheist must concede that the source of order is at least remotely like a human intellect, even if this source is something like a rotting turnip. This passage provides a major argument for dismissing Hume’s apparent avowals of theism in the Dialogues and elsewhere, (...) since Philo’s assertions are so loose as to let in a rotting turnip. The right reading of the passage is more interesting. The paragraph was written in 1776, right before Hume’s death. It’s thus one of the few philosophical texts written late enough to reflect his encounter with the French philosophes in the 1760s. We have good biographical evidence that Hume was criticized for being too much of a theist in France. The turnip is rotting not in order to make fun of the argument from design, but in order to make fun of d’Holbach's and Diderot's account of the origin of life, accounts that generalized dramatically from John Needham’s observations of nematodes in rotting wheat. In the rotting turnip paragraph, Hume is attempting to establish that the dispute between the theist and the atheist isn’t empirically tractable, that atheists will never outflank the apophatic theologian on the question of whether human minds are unlike God, and that if atheists are consistent with their analogical methods, they ought to be more open to the argument from design. (shrink)

The first argument that Hume offers against believing in miracle stories in Part 2 of his essay on miracles relies on social context in a way that makes it difficult to follow. Hume says that there’s never been a miracle story that’s well enough attested with respect to certain criteria of testimonial strength. A little later in the essay, he cites recent miracle stories coming from that Saint Médard cemetery as meeting the criteria to an exceptionally high degree, but even (...) so, he claims that we can dismiss the stories out of hand. The hidden background assumption is that his Protestant readers wouldn’t have been tempted to believe in miracle stories coming from an oppressed Catholic sect. Other examples in Part 2 of the essay work in the same way. Hume praises to the skies the quality of the evidence for an earlier Jansenist miracle, for a miracle involving the restoration of a leg through holy water at a Catholic cathedral, and a miracle at a temple of Serapis knowing that his readers won’t be inclined to believe in any of them. The point is that these miracles are better attested than the miracle stories in the Bible, and if we shouldn’t believe in the better attested stories, then we shouldn’t believe in the worse. This can seem like an appeal to prejudice, but really Hume is doing something subtler. He knows that it’s easier to criticize the irrational beliefs of others, but sees that once we turn the same standards that we use on others on our own beliefs, epistemic progress is possible. (shrink)

The fact that Gilbert Ryle and J.L. Austin seem to disagree about the ordinary use of words such as ‘voluntary’, ‘involuntary’, ‘voluntarily’, and ‘involuntarily’ has been taken to cast doubt on the methods of ordinary language philosophy. As Benson Mates puts the worry, ‘if agreement about usage cannot be reached within so restricted a sample as the class of Oxford Professors of Philosophy, what are the prospects when the sample is enlarged?’ (Mates, Inquiry 1:161–171, 1958, p. 165). In this chapter, (...) we evaluate Mates’s criticism alongside Ryle’s and Austin’s specific claims about the ordinary use of these words, assessing these claims against actual examples of ordinary use drawn from the British National Corpus (BNC). Our evaluation consists in applying a combination of methods: first aggregating judgments about a large set of samples drawn from the corpus, and then using a clustering algorithm to uncover connections between different types of use. In applying these methods, we show where and to what extent Ryle’s and Austin’s accounts of the use of the target terms are accurate as well as where they miss important aspects of ordinary use, and we demonstrate the usefulness of this new combination of methods. At the heart of our approach is a commitment to the idea that systematically looking at actual uses of expressions is an essential component of any approach to ordinary language philosophy. (shrink)

In this article we defend a moral conception of cosmopolitanism and its relevance for moral education. Our moral conception of cosmopolitanism presumes that persons possess an inherent dignity in the Kantian sense and therefore they should be recognised as ends‐in‐themselves. We argue that cosmopolitan ideals can inspire moral educators to awaken and cultivate in their pupils an orientation and inclination to struggle against injustice. Moral cosmopolitanism, in other words, should more explicitly inform the work that moral educators do. Real‐world constraints (...) on moral action and the need to prioritise one’s sometimes conflicting responsibilities will often qualify cosmopolitan justice as supererogatory. This fact does not absolve persons from aspiring to see themselves as having the moral obligation to help others in need, while recognising that their factual obligations are more modest in being bound by what they are actually able to do. (shrink)

Even though fatalism has been an intermittent topic of philosophy since Greek antiquity, this paper argues that fate ought to be of little concern to metaphysicians. Fatalism is neither an interesting metaphysical thesis in its own right, nor can it be identified with theses that are, such as realism about the future or determinism.

Michael Sandel's opposition to the project of human enhancement is based on an argument that centres on the notion of giftedness. Sandel claims that by trying to ?make better people? we fall prey to, and encourage, an attitude of mastery and thus lose, or diminish, our appreciation of the giftedness of life. Sandel's position and the underlying argument have been much criticised. In this paper I will try to make sense of Sandel's reasoning and give an account of giftedness (...) that defends its relevance for the ethical assessment of the human enhancement project. In order to do so, I will also look at virtue-related notions, such as gratitude and humility, and distinguish the gifted from the merely given. The failure to acknowledge this distinction gives rise to one of the most common objections to Sandel's argument. Other objections will be shown to rest on similar misunderstandings. (shrink)

This chapter explores a potential analogy between mereological principles and laws of nature. Against a backdrop of what Marmodoro has termed ‘power structuralism’ (and a rejection of a Humean worldview), the connection between parthood and modality may be richer than has hitherto been considered. Mereological principles delineate possibilities for parts and wholes, and putting powers at the centre of a discussion about parthood can furnish a novel conception of mereological laws, much as dispositionalism has done so for natural laws; namely, (...) these principles express connections between fundamental dispositional properties. By extending dispositionalism to comprehend mereology in this way, we can help fulfil its promise to provide a foundational, naturalistic metaphysics, as foundational mereological debates then begin to mirror those relating to dispositionalist views of laws of nature: we may treat natural and mereological laws in tandem, as holding either necessarily or contingently, with associated strategies for dealing with supposed counterexamples to one’s preferred set of mereological principles. We can thus bring new life to the debate over whether questions of composition admit of contingent or only necessary answers. (shrink)

Claudia Card did not live long enough to complete her work on surviving evils. Yet she left us an invaluable body of work on this topic. This essay surveys Card's views about the nature of evils and the ethical quandaries of surviving them. It then develops an account of survival agency that is based on Card's insights and in keeping with the agentic capacities exercised by Yezidi women and girls who have escaped from ISIS's obscene program of trafficking in women (...) and sexual violence. Card holds that true survival requires not only staying alive and as healthy as possible but also preserving your good moral character. The essay maintains that while exercising agency to elude evil and protect yourself often depends on your own skills and personality traits, exercising agency to restore or develop your moral character often depends on social support. (shrink)

The essay brings a summation of human efforts seeking to understand our existence. Plato and Kant & cognitive science complete reduction of philosophy to a neural mechanism, evolved along elementary Darwinian principles. Plato in his famous Cave Allegory explains that between reality and our experience of it there exists a great chasm, a metaphysical gap, fully confirmed through particle-wave duality of quantum physics. Kant found that we have two kinds of perception, two senses: By the spatial outer sense we perceive (...) phenomena, objects in space. Our temporal inner sense lets us perceive our inner state, noumena . Kant's two senses are fully confirmed through bilateral brain duality of cognitive science. The bilateral brain serves inner, temporal sense, logic & noumena in the left hemisphere. The right brain half is for the outer, spatial sense, geometry & phenomena. We form a whole system, a bilateral interior cosmos, a kind of world model, expressing what may lie beyond the metaphysical gap. In the right brain we build a phenomenal cosmos, to resemble the outer environment. In the brain's left hemisphere a noumenal cosmos, a model of our private world including Saint Teresa of Avila's castillo interior. The cosmos is regularly updated with novel sense data integrated into our memory banks. This was recognized early by Helmholtz (1860s). Our lives, health & well-being depend on us keeping our interior cosmos in good order. This used to be seen as saving one's precious soul from perdition. While we endeavour to keep our phenomenal cosmos neat & orderly by protecting the environment from harm, our noumenal cosmos to be livable requires us to engage in ethical conduct. This bilateral cosmos is responsible for our common sense judgment power, that we depend on for being able to lead a good & benign life. The 200 million neurons of BA10 in the prefrontal lobe have global access to the interior cosmos, & apply massive feedback to identify environmental conditions rapidly. The global access also gives conscious presence of the individual to itself, all that is present in the interior cosmos, for total freedom of action. In the left brain private ego, we are guarded by faith in divine mercy, & guided to choose the best course of action, able to survive under the most adverse conditions. For this, we receive directions from the Holy Ghost in Saint Teresa's castillo interior. (shrink)

A perceptual realism that is naive in a good way must be naively realistic about world and mind. But contemporary self-described naive realists often have trouble acknowledging that both the good cases of successful perception and the bad cases of illusion and hallucination involve internal experiential states with intentional contents that present the world as being a certain way. They prefer to think about experience solely in relational terms because they worry that otherwise we won’t be able to escape from (...) radical skepticism. I argue that experiential relations to objects require that their subjects be in internal experiential states. But this does not mean that these states are our epistemological starting point which can be known independently of any knowledge of the external world. We do escape the epistemological predicament of radical skepticism because the good cases are primary over the bad ones. But this is not because the good cases alone provide reasons for belief, but because we do not need a reason to think we are in a good case, but do need a reason to think we are not, and such a reason must come from a good case. So bad cases can only be thought of as deviations from good cases. And we can only understand experiences as states with contents distinct from their objects and present in good and bad cases once we understand misrepresentation, that is, bad cases, and therefore only as we ascribe knowledge of the external world to ourselves. (shrink)

Conscious existence is the product of a neural brain mechanism, which is largely identical with Immanuel Kant's Oneness Function, a service performed by 200 million neurons in the prefrontal lobe, & makes possible our interior cosmos, the record of our interconnected, or general, experience. Essential for us humans is the well-being of our interior cosmos, or Saint Teresa of Avila's interior castle, in all interactions with each other \& the greater environment. Any disorders of our cosmos are liable to make (...) us fall ill, setting our existence on a path of psychosomatic etiology of a large class of mysterious undiagnosed diseases. (shrink)

Recent advances in neuroscience lead to a wider realm for philosophy to include the science of the Darwinian-evolved computational brain, our inner world producing organ, a non-recursive super- Turing machine combining 100B synapsing-neuron DNA-computers based on the genetic code. The whole system is a logos machine offering a world map for global context, essential for our intentional grasp of opportunities. We start from the observable contrast between the chaotic universe vs. our orderly inner world, the noumenal cosmos. So far, philosophy (...) has been rehearsing our thoughts, our human-internal world, a grand painting of the outer world, how we comprehend subjectively our experience, worked up by the logos machine, but now we seek a wider horizon, how humans understand the world thanks to Darwinian evolution to adapt in response to the metaphysical gap, the chasm between the human animal and its environment, shaping the organism so it can deal with its variable world. This new horizon embraces global context coded in neural structures that support the noumenal cosmos, our inner mental world, for us as denizens of the outer environment. Kant’s inner and outer senses are fundamental ingredients of scientific philosophy. Several sections devoted to Heidegger, his lizard debunked, but his version of the metaphysical gap & his doctrine of the logos praised. Rorty and others of the behaviorist school discussed also. (shrink)

From the earliest times, American ethics, the rules for the moral \& intellectual life of the West, used to be founded upon the two principles of self-reliance and good neighborliness. Here we consider the underlying functions of neural brain circuits, organic structures that have evolved adaptively by Darwinian rules subject to selection pressure. In the left brain resides our self-reliant private Ego, making plans, launching initiatives. Your public Ego dwells in the right brain, looking around, meeting with your friendly neighbor. (...) A main component is our bilateral interior cosmos, providing us with all the detailed information about our environment as well as the universe at large. (shrink)

This chapter offers an account of Crusius’ conception of freedom. In the first part of the chapter I sketch Crusius’ understanding of ‘Thelematology’ or ‘science of the will’ and his conception of the will itself. In the second part of the paper I provide an account of Crusius’ conception of freedom of the will and I focus on two topics: his understanding of freedom as self-determination and his conception of free choice. Contrary to how some of the secondary literature portrays (...) his view, I argue that freedom of the will, for Crusius, is not best described as the freedom to choose otherwise or liberty of indifference. On the contrary, Crusius argues that free choice is rarely indifferent to its choices and is most often strongly inclined towards certain ends that free choice must overcome and choose against. (shrink)

Ethical debates about assisted dying typically assume that only medical professionals should be able to provide patients with assisted dying. This assumption partially rests on the unstated principle that assisted dying providers may not be motivated by pecuniary considerations. Here I outline and defend a mixed provider model of assisted dying provision that contests this principle. Under this model, medically competent non-physician professionals could receive fees for providing assisted dying under the same terms and conditions as physicians can in those (...) juris- dictions where medically assisted dying is lawful. The mixed provider model blunts objections to assisted dying rooted in supposed clashes with medical values. In addition to generating a market likely to expand access to assisted dying, the mixed provider model would not create markets that are unjust because they are “noxious” in Satz’ sense or because they raise “semiotic” concerns about the value of human life. (shrink)

The evidence is overwhelming that members of particularly wealthy and industry-owning segments of Western societies have much larger carbon footprints than most other humans, and thereby contribute far more than their “fair share” to the enormous problem of climate change. Nonetheless, in this paper we shall counsel against a strategy focused primarily on blaming and shaming and propose, instead, a change in the ethical conversation about climate change. We recommend a shift in the ethical framework from a focus on the (...) role of individual agents and a conversation about guilt; in its place, we propose a relational approach to public health ethics that is centered around the idea of relational solidarity. We begin by briefly reviewing the most common—and woefully inadequate—approach in the West to reducing emissions and responding to the health-related impacts of climate change. We then go on to propose a relational approach to public health ethics as an alternative ethical framework that better fits the moral problems associated with climate change and holds promise for a more meaningful response. (shrink)

In this paper, I undertake a conceptual analysis of ordinary usages of the concepts of “litter” and “pollution.” If “litter” or “pollution” applies to space debris in its various contexts, then in dealing with space debris as an ethical concern, we may more neatly apply arguments for the wrongness of litter and pollution to these new contexts. After engaging in a conceptual analysis of “litter” and “pollution,” I consider whether these concepts apply to space debris, examining three contexts: (1) surface (...) debris on Moon and Mars, (2) intentionally crashing objects into gas giants, ice giants, and stars, and (3) the pressing issue of orbital space debris. I conclude by finding that neither “litter” nor “pollution” cleanly applies to any of these three contexts. (shrink)

My goal in this paper is to show that naturalists cannot reasonably endorse moral realism. My argument will come in two parts. The first part aims to show that any plausible and naturalistically acceptable argument in favor of belief in objective moral properties will appeal in part to simplicity considerations (broadly construed)—and this regardless of whether moral properties are reducible to non-moral properties. The second part argues for the conclusion that appeals to simplicity justify belief in moral properties only if (...) either those properties are not objective or something like theism is true. Thus, if my argument is sound, naturalists can reasonably accept moral realism only if they are prepared to accept something like theism. But, as will become clear, naturalists can reasonably accept theism or something like it only if belief in some such doctrine is justified by the methods of science. For present purposes, I’ll assume (what I think virtually every naturalist will grant) that belief in theism and relevantly similar doctrines is not justified by the methods of science. Thus, I will conclude that naturalists cannot reasonably accept moral realism. (shrink)

Discussions of divine simplicity generally overlook the distinction between identity claims that are reductivist and identity claims that are eliminativist. If, for instance, the identity claim that 'the chair = a configuration of particles' is merely reductive, then there exist chairs and there exist configurations of particles and it turns out that they are identical. The identity in this case does not reduce the ontological complexity of the world. But if the identity claim is eliminativist, then it is true again (...) that chairs are configurations of particles, but chairs do not in fact exist. The illusory object that we call a chair turns out to be nothing over and above a configuration of physical particles. The chair reduces to the configuration of particles without remainder. The defense of divine simplicity in this paper argues that it is in this eliminativist sense that God's intrinsic properties are identical to God. (shrink)

What is 'positive freedom'? Whereas negative freedom may be characterised as an absence of coercion or physical prevention, and republican freedom as an absence of interpersonal domination, positive freedom resists such pithy treatment. The term is widely taken to refer to a variety of seemingly distinct goods, including but not limited to actually exercisable options or capabilities, collective self-determination, psychological self-government, and self-realisation or flourishing. In this paper I aim to bring the positive conception into better focus by tracing the (...) positive tradition through some of its twists and turns, and considering in what ways it might qualify as a single tradition. Drawing on the lessons of this survey, I then suggest a way of thinking about the nature of positive freedom that’s both principled and historically informed. (shrink)

It is commonly believed that intrinsically bad possible worlds are inconsistent with the perfect goodness of God. A perfectly good being could not exist in possible worlds that are intrinsically bad. Indeed it is widely believed that possible worlds that are insufficiently good are inconsistent with a perfectly good God. Modal atheological arguments aim to show that, since the pluriverse includes intrinsically bad worlds and insufficiently good worlds, there necessarily does not exist a perfectly good God. I show that modal (...) atheological arguments are in general invalid. Modal atheological arguments fail to show that there exists no perfectly good God even on the assumption that there are extremely bad worlds in the pluriverse. Modal atheological arguments depend entirely on the logic of modality in S5. But the logic of S5 ensures that a perfectly good God is consistent with extremely bad possible worlds and so guarantees that a perfectly good God is consistent with a plenitudinous pluriverse. (shrink)

In recent decades, perspectivism has developed into an epistemological research program claiming its independence. This autonomy stems from Perspectivism’s potential ability to resolve the contradictions between realist and constructivist programs. Perspectivism is based on the idea that the object depends on perspective, which constitutes any subjective attempt to cognize it. Perspectivists reconstruct and explain the factors involved in the formation of perspective, identifying the conditionality of epistemic acts, using concepts such as “position”, “point of view”, “view”, “angle”, “horizon”, “focus”, “picture”, (...) “context”, “aspect”, etc. Although these concepts are part of the perspectivist’s toolkit, their meanings and interrelation have so far been taken for granted and have not yet been critically and comprehensively analyzed. The purpose of this article is to take steps toward clarifying the conceptual basis for defending perspectivism as an epistemological program. Once consistently uncovered and correlated in a conceptual model, Perspectivist concepts can be used as a tool for a detailed analysis of theories, positions, and beliefs. The article begins with a preliminary description of the concept of perspectivism and its brief history as an epistemological program. In particular, the first modern attempts to outline perspectivist epistemology are described in the works of F. Kaulbach (1990), W. Stegmaier (2008), and M. Massimi (2017, 2020). The problem of identifying the special a priori status of perspectivist notions as a strategy for justifying the autonomy of Perspectivism is then posed. A method for demonstrating such a status, based on Kant’s transcendentalism and P. Strawson’s descriptive metaphysics, is then suggested. (shrink)

How surprising is the insight, that being equals I in the 15th lecture of the Doctrine of Science 1804/II? It might have been indeed an unexpected turn for his contemporaries in Berlin listening to Fichte for the first time, but should it be surprising for us, having at least since 2012 (the year the last volume of [Gesamtausgabe] appeared) access to all his published and unpublished works? I want to propose a way of reading Fichte, which bypasses two popular and (...) contradictory interpretations of his philosophy in the post-Jena period: (a) the Absolute is the new first principle (hence the I is just a shadow of the much higher being) and (b) his system basically remains unchanged (hence the being is nothing more than the I). At first, I analyze the functions of later Fichte’s improved version of the Kantian and Reinholdian abstract subject-object-symbolism and assign specific content to it. This will shed light on the structure and the first principle of the Doctrine of Science 1804/II. In the second section I give reasons why Fichte calls both God and I “absolute” and “pure being” and explain their relation to each other referring to a thought experiment sometimes used by Kant—an analogy between the divine and human (pure) reason. The analogical thinking of this kind remains within the borders of transcendental philosophy as long as it is used only for certain didactic purposes. (shrink)

Origin of the Yellowstone hotspot & Columbia River Basalts has remained uncertain until now. Here, we present evidence of meteorite impact origin. The hotspot is shallow, only 200 km deep, invalidating a theory of mantle plume origin. The hotspot track runs from the Yellowstone National Park in NW Wyoming to the volcanic Modoc Plateau in NE California. We present evidence of apparent remnants of an impact crater existing in the Modoc, a large multi-ring structure at least 160 km diameter. Much (...) of the complex crater has become obliterated by later Cascadia and Sierra orogenies. The crater has a tall 4,100 foot central uplift cone, locally known as Chalk Mountain, consisting of diatomaceous earth, presumably the rebound cone of a meteorite impact. This falsifies a theoretical prohibition of cosmic impact volcanism. Based on recent insights into explosive volcanism a plausible mechanism is proposed for how meteorite impacts can lead to resurgent calderas of the Yellowstone type, & of apparent LIP origin from thin crust ET impacts, invalidating theoretical constructs of mantle plumes. We mention chaotic terrains, including plutons, arising antipodal to impacts. (shrink)

Guided by key insights of the four great philosophers mentioned in the title, here, in review of and expanding on our earlier work (Burchard, 2005, 2011), we present an exposition of the role played by language, & in the broader sense, λογοζ, the Logos, in how the CNS, the brain, is running the human being. Evolution by neural Darwinism has been forcing the linguistic nature of mind, enabling it to overcome & exploit the cognitive gap between an animal and its (...) world by recognizing environmental structures. Our work was greatly influenced by Heidegger’s lecture notes on metaphysics (Heidegger, 1935). We found agreement with recent progress in neuroscience, but also mathematical foundations of language theory, equating Logos with the mathematical concept of structure. The mystery of perception across the gap is analyzed as radiation and molecules impinging on sensory neurons that carry linguistic information about gross environmental structures, and only remotely about the physical reality of elementary particles. The most important logical brain function is Ego or Self, guiding the workings of the brain as a logos machine. Ego or Self operates from neurons in frontopolar cortex with global receptive fields. The logos machine can function only by availing itself of global context, its internally stored noumenal cosmos NK, and the categorical-conceptual apparatus CCA, updated continually through the neural default mode network (Raichle, 2005). In the Transcendental Deduction, Immanuel Kant discovered that Ego or Self is responsible for conscious control in perception relying on concepts & categories for a fitting percept to be incorporated intoNK. The entire CNS runs as a “movie-in-the-brain” (Parvizi & Damasio, 2001), at peak speed processing simultaneously in a series of cortical centers a stack of up to twelve frames in gamma rhythm of 25 ms intervals. We equate global context, or NK, with our human world, Heidegger’s Dasein being-in-the-world, and are able to demonstrate that the great philosopher in EM parallels neuro-science concerning the human mind. (shrink)

In this essay, our goal is to discover science in Martin Heidegger's Introduction to Metaphysics, lecture notes for his 1935 summer semester course, because, after all, his subject is metaphysica generalis, or ontology, and this could be construed as a theory of the human brain. Here, by means of verbatim quotes from his text, we attempt to show that indeed these lectures can be viewed as suggestion for an objective scientific theory of human perception, the human capacity for deciphering phenomena, (...) ie. hermeneutics in its broadest sense. His added notes from the 1953 edition, all of which are comments, not corrections, imply that he never abandoned these thoughts on metaphysics, despite all of his utterances about a need to overcome it, and their popular interpretations to that effect. In his presentation, he further develops the colorful and intuitive style, an hermeneutic language, that he had created in his earlier work Being and Time. Of human existence he speaks in such expressions as being-there -- ``Dasein" -- and being-in-the-world, the latter term no longer explicit in the 1935 lectures. The lectures can be read as a pre-scientific analysis of how man, being-there, perceives his environment, artfully managing to deal with the manifold challenges posed by the phenomenal structures of the universe. Man attentively recognizes and deciphers their pre-linguistic contents and, while trying to make sense of it all, puts into words his awareness. There are numerous passages in Heidegger's work where he in fairly concrete terms provides us with hints for a perceptive science that, as it turns out and is demonstrated below in this essay, can be explained in terms of recent advances in neuroscience. It would be implausible, even unthinkable, unimaginable, for there not to be found essential agreement between on one hand his philosophical insights gained by hermeneutics of Dasein, into how our brain functions to let us know what's happening & on the other hand, scientific discoveries obtained through anatomy, EEG, fMRI, TMS, electrode implants, etc, of brain structures & functions employed in perception of the momentary scene. A nexus between science and philosophy is provided in Heidegger's definitive treatment of the Logos, here interpreted as a structural version of Platonic forms (Burchard, 2014). This allows for neurolinguistic brain functions to serve as meta-context for Heidegger's being-in-the-world. The logical functions of Dasein's anatomical brain are performed by the logos machine, formerly the human soul, using top-down processing based on a global context, the noumenal cosmos which humans maintain internally. Heidegger's 1942/43 winter semester lectures Parmenides extend in unbroken fashion his 1935 work, proving that he never abandoned, as is widely claimed, his metaphysical avenue of thought. (shrink)

This chapter discusses the nature and value of political disagreement, with reference to contemporary work in political philosophy. I will attempt to answer the following questions: Why do we disagree? Is political disagreement a good thing? Do we have a duty to disagree? Should we expect consensus or mere compromise in politics? When is civil disobedience a justified way to express disagreement with the law? Is consensus a threat to democracy?

Georg Cantor's absolute infinity, the paradoxical Burali-Forti class Ω of all ordinals, is a monstrous non-entity for which being called a "class" is an undeserved dignity. This must be the ultimate vexation for mathematical philosophers who hold on to some residual sense of realism in set theory. By careful use of Ω, we can rescue Georg Cantor's 1899 "proof" sketch of the Well-Ordering Theorem––being generous, considering his declining health. We take the contrapositive of Cantor's suggestion and add Zermelo's choice function. (...) This results in a concise and uncomplicated proof of the Well-Ordering Theorem. (shrink)

Alternative currencies are means of payment that circulate alongside—as an alternative or complement to—official currencies. While these currencies have existed for a long time, both society and academia have shown a renewed interest in their potential to decentralize the governance of monetary affairs and to bring people and organizations together in more ethical or sustainable ways. This article is a review of the ethical and philosophical implications of these alternative monetary projects. We first discuss various classifications of these currencies before (...) analyzing the ethical challenges linked to the way they tackle social and environmental issues. We also examine the incentive-based and coercive mechanisms used by these currencies from an ethical perspective and debate the promises and perils of monetary decentralization and democracy. We conclude by identifying an agenda for future research. (shrink)

The history of the methodology of African philosophy can be divided into two periods: the nascent stage that’s characterized by a rigor-demand, and the contemporary stage that’s characterized by a relevance-demand. In this, paper, I argue for one way to strike the appropriate balance between relevance and rigor in African philosophy. Specifically, I argue that the unconscious rejection of conceptual analysis as a philosophical method by contemporary African philosophers played a major role in how African philosophy came to be characterized (...) by a relevance-demand. Consequently, I submit that even though being only or excessively relevance-oriented is not bad, African philosophy would become rich enough to compete with other regional philosophies—Western, Chinese, and so on—if it re-installs conceptual analysis as part of its methodology. (shrink)

_ Source: _Volume 95, Issue 3, pp 368 - 413 Frege famously maintained that concepts are not objects. A key argument of Frege’s for this view is, in outline, as follows: if we are to account for the unity of thought, concepts must be deemed _unsaturated_; since objects are, by contrast, saturated entities, concepts cannot be objects. The author investigates what can be made of this argument and, in particular, of the unsaturated/saturated distinction it invokes. Systematically exploring a range of (...) reconstructions suggested by Frege’s writings, and drawing on contemporary work, the author illustrates that no plausible reconstruction is forthcoming. In essence, it is altogether unclear how to simultaneously substantiate, on the one hand, the claim that unsaturated entities must be recognized in order to account for unity and, on the other, the claim that unsaturatedness is incompatible with objecthood. (shrink)

Political epistemology is a newly flourishing area of philosophy, but there is no comprehensive overview to this burgeoning field. This chapter maps out the terrain of political epistemology, highlights some of the key questions and topics of this field, draws connections across seemingly disparate areas of work, and briefly situates this field within its historical and contemporary contexts.