Decisions, whether moral or prudential, should be guided at least in part by considerations of the consequences that would result from the various available actions. For any given action, however, the majority of its consequences are unpredictable at the time of decision. Many have worried that this leaves us, in some important sense, clueless. In this paper, I distinguish between ‘simple’ and ‘complex’ possible sources of cluelessness. In terms of this taxonomy, the majority of the existing literature on cluelessness focusses (...) on the simple sources. I argue, contra James Lenman in particular, that these would-be sources of cluelessness are unproblematic, on the grounds that indifference-based reasoning is far less problematic than Lenman (along with many others) supposes. However, there does seem to be a genuine phenomenon of cluelessness associated with the ‘complex’ sources; here, indifference-based reasoning is inapplicable by anyone’s lights. This ‘complex problem of cluelessness’ is vivid and pressing, in particular, in the context of Effective Altruism. This motivates a more thorough examination of the precise nature of cluelessness, and the precise source of the associated phenomenology of discomfort in forced-choice situations. The latter parts of the paper make some initial explorations in those directions. (shrink)

I present an argument for the view that laws ground their instances. I then outline two important consequences that follow if we accept the conclusion of this argument. First, the claim that laws ground their instances threatens to undermine a prominent recent attempt to make sense of the explanatory power of Humean laws by distinguishing between metaphysical and scientific explanation. And second, the claim that laws ground their instances gives rise to a novel argument against the view that grounding relations (...) are metaphysically necessary. (shrink)

The goal of this paper is to sketch and defend a new interpretation or 'theory' of objective chance, one that lets us be sure such chances exist and shows how they can play the roles we traditionally grant them. The account is 'Humean' in claiming that objective chances supervene on the totality of actual events, but does not imply or presuppose a Humean approach to other metaphysical issues such as laws or causation. Like Lewis (1994) I take the Principal Principle (...) (PP) to be the key to understanding objective chance. After describing the main features of Humean objective chance (HOC), I deduce the validity of PP for Humean chances, and end by exploring the limitations of Humean chance. (shrink)

This is a three-part exchange on the relationship between belief and credence. It begins with an opening essay by Roger Clarke that argues for the claim that the notion of credence generalizes the notion of belief. Julia Staffel argues in her reply that we need to distinguish between mental states and models representing them, and that this helps us explain what it could mean that belief is a special case of credence. Roger Clarke's final essay reflects on the compatibility of (...) the previously discussed views with dualist and monist interpretations of our mental states and our ways of modeling them. (shrink)

This is an extensive review of recent work on the foundations of statistical mechanics.

How do we ascribe subjective probability? In decision theory, this question is often addressed by representation theorems, going back to Ramsey (1926), which tell us how to define or measure subjective probability by observable preferences. However, standard representation theorems make strong rationality assumptions, in particular expected utility maximization. How do we ascribe subjective probability to agents which do not satisfy these strong rationality assumptions? I present a representation theorem with weak rationality assumptions which can be used to define or measure (...) subjective probability for partly irrational agents. (shrink)

Skeptical hypotheses such as the brain-in-a-vat hypothesis provide extremely poor explanations for our sensory experiences. Because these scenarios accommodate virtually any possible set of evidence, the probability of any given set of evidence on the skeptical scenario is near zero; hence, on Bayesian grounds, the scenario is not well supported by the evidence. By contrast, serious theories make reasonably specific predictions about the evidence and are then well supported when these predictions are satisfied.

Four important arguments for probabilism—the Dutch Book, representation theorem, calibration, and gradational accuracy arguments—have a strikingly similar structure. Each begins with a mathematical theorem, a conditional with an existentially quantified consequent, of the general form: if your credences are not probabilities, then there is a way in which your rationality is impugned. Each argument concludes that rationality requires your credences to be probabilities. I contend that each argument is invalid as formulated. In each case there is a mirror-image theorem and (...) a corresponding argument of exactly equal strength that concludes that rationality requires your credences not to be probabilities. Some further consideration is needed to break this symmetry in favour of probabilism. (shrink)

Entropy is ubiquitous in physics, and it plays important roles in numerous other disciplines ranging from logic and statistics to biology and economics. However, a closer look reveals a complicated picture: entropy is defined differently in different contexts, and even within the same domain different notions of entropy are at work. Some of these are defined in terms of probabilities, others are not. The aim of this chapter is to arrive at an understanding of some of the most important notions (...) of entropy and to clarify the relations between them, After setting the stage by introducing the thermodynamic entropy, we discuss notions of entropy in information theory, statistical mechanics, dynamical systems theory and fractal geometry. (shrink)

‘Bayesian epistemology’ became an epistemological movement in the 20th century, though its two main features can be traced back to the eponymous Reverend Thomas Bayes (c. 1701-61). Those two features are: (1) the introduction of a formal apparatus for inductive logic; (2) the introduction of a pragmatic self-defeat test (as illustrated by Dutch Book Arguments) for epistemic rationality as a way of extending the justification of the laws of deductive logic to include a justification for the laws of inductive logic. (...) The formal apparatus itself has two main elements: the use of the laws of probability as coherence constraints on rational degrees of belief (or degrees of confidence) and the introduction of a rule of probabilistic inference, a rule or principle of conditionalization. (shrink)

Many activities impose risks of harm on other people. One such class of risks are those that individuals culpably impose on others, such as the risk arising from reckless driving. Do such risks in themselves constitute a harm, over and above any harm that actually eventuates? This paper considers three recent views that each answer in the affirmative. I argue that each fails to overcome what I call the ‘interference objection’. The risk of harm itself, whether taken as a subjective (...) or an objective risk, is unable to interfere with the interests of victims in order to constitute a harm. This does not mean that a risk of harm cannot itself be wrongful, but the conclusion does weaken the moral objectionableness of impositions of risks of harm. (shrink)

The anti-causal prophecies of last century have been disproved. Causality is neither a ‘relic of a bygone’ nor ‘another fetish of modern science’; it still occupies a large part of the current debate in philosophy and the sciences. This investigation into causal modelling presents the rationale of causality, i.e. the notion that guides causal reasoning in causal modelling. It is argued that causal models are regimented by a rationale of variation, nor of regularity neither invariance, thus breaking down the dominant (...) Human paradigm. The notion of variation is shown to be embedded in the scheme of reasoning behind various causal models: e.g. Rubin’s model, contingency tables, and multilevel analysis. It is also shown to be latent – yet fundamental – in many philosophical accounts. Moreover, it has significant consequences for methodological issues: the warranty of the causal interpretation of causal models, the levels of causation, the characterisation of mechanisms, and the interpretation of probability. This book offers a novel philosophical and methodological approach to causal reasoning in causal modelling and provides the reader with the tools to be up to date about various issues causality rises in social science. (shrink)

“Probabilistic Causation” designates a group of theories that aim to characterize the relationship between cause and effect using the tools of probability theory. The central idea behind these theories is that causes change the probabilities of their effects. This article traces developments in probabilistic causation, including recent developments in causal modeling. A variety of issues within, and objections to, probabilistic theories of causation will also be discussed.

The word ‘probability’ in ordinary language has two different senses, here called inductive and physical probability. This paper examines the concept of inductive probability. Attempts to express this concept in other words are shown to be either incorrect or else trivial. In particular, inductive probability is not the same as degree of belief. It is argued that inductive probabilities exist; subjectivist arguments to the contrary are rebutted. Finally, it is argued that inductive probability is an important concept and that it (...) is a mistake to try to replace it with the concept of degree of belief, as is usual today. (shrink)

I argue that any broadly dispositional analysis of probability will either fail to give an adequate explication of probability, or else will fail to provide an explication that can be gainfully employed elsewhere (for instance, in empirical science or in the regulation of credence). The diversity and number of arguments suggests that there is little prospect of any successful analysis along these lines.

Evolutionary theory is awash with probabilities. For example, natural selection is said to occur when there is variation in fitness, and fitness is standardly decomposed into two components, viability and fertility, each of which is understood probabilistically. With respect to viability, a fertilized egg is said to have a certain chance of surviving to reproductive age; with respect to fertility, an adult is said to have an expected number of offspring.1 There is more to evolutionary theory than the theory of (...) natural selection, and here too one finds probabilistic concepts aplenty. When there is no selection, the theory of neutral evolution says that a gene’s chance of eventually reaching fixation is 1/(2N), where N is the number of organisms in the generation of the diploid population to which the gene belongs. The evolutionary consequences of mutation are likewise conceptualized in terms of the probability per unit time a gene has of changing from one state to another. The examples just mentioned are all “forwarddirected” probabilities; they describe the probability of later events, conditional on earlier events. However, evolutionary theory also uses “backwards probabilities” that describe the probability of a cause conditional on its effects; for example, coalescence theory allows one to calculate the expected number of generations in the past that the genes in the present generation find their most recent common ancestor. (shrink)

Philosophers now seem to agree that frequentism is an untenable strategy to explain the meaning of probabilities. Nevertheless, I want to revive frequentism, and I will do so by grounding probabilities on typicality in the same way as the thermodynamic arrow of time can be grounded on typicality within statistical mechanics. This account, which I will call typicality frequentism, will evade the major criticisms raised against previous forms of frequentism. In this theory, probabilities arise within a physical theory from statistical (...) behavior of almost all initial conditions. The main advantage of typicality frequentism is that it shows which kinds of probabilities (that also have empirical relevance) can be derived from physics. Although one cannot recover all probability talk in this account, this is rather a virtue than a vice, because it shows which types of probabilities can in fact arise from physics and which types need to be explained in different ways, thereby opening the path for a pluralistic account of probabilities. (shrink)

The epistemic state of complete ignorance is not a probability distribution. In it, we assign the same, unique, ignorance degree of belief to any contingent outcome and each of its contingent, disjunctive parts. That this is the appropriate way to represent complete ignorance is established by two instruments, each individually strong enough to identify this state. They are the principle of indifference (PI) and the notion that ignorance is invariant under certain redescriptions of the outcome space, here developed into the (...) ‘principle of invariance of ignorance' (PII). Both instruments are so innocuous as almost to be platitudes. Yet the literature in probabilistic epistemology has misdiagnosed them as paradoxical or defective since they generate inconsistencies when conjoined with the assumption that an epistemic state must be a probability distribution. To underscore the need to drop this assumption, I express PII in its most defensible form as relating symmetric descriptions and show that paradoxes still arise if we assume the ignorance state to be a probability distribution. *Received February 2007; revised July 2007. †To contact the author, please write to: Department of History and Philosophy of Science, University of Pittsburgh, Pittsburgh, PA 15260; e-mail: [email protected]. (shrink)

Both Popper and van Fraassen have used evolutionary analogies to defend their views on the aim of science, although these are diametrically opposed. By employing Price's equation in an illustrative capacity, this paper considers which view is better supported. It shows that even if our observations and experimental results are reliable, an evolutionary analogy fails to demonstrate why conjecture and refutation should result in: (1) the isolation of true theories; (2) successive generations of theories of increasing truth-likeness; (3) empirically adequate (...) theories; or (4) successive generations of theories of increasing proximity to empirical adequacy. Furthermore, it illustrates that appeals to induction do not appear to help. It concludes that an evolutionary analogy is only sufficient to defend the notion that the aim of science is to isolate a particular class of false theories, namely those that are empirically inadequate. (shrink)

According to so-called epistemic theories of conditionals, the assertability/acceptability/acceptance of a conditional requires the existence of an epistemically significant relation between the conditional’s antecedent and its consequent. This paper points to some linguistic data that our current best theories of the foregoing type appear unable to explain. Further, it presents a new theory of the same type that does not have that shortcoming. The theory is then defended against some seemingly obvious objections.

In this paper we explore the connections between ethics and decision theory. In particular, we consider the question of whether decision theory carries with it a bias towards consequentialist ethical theories. We argue that there are plausible versions of the other ethical theories that can be accommodated by “standard” decision theory, but there are also variations of these ethical theories that are less easily accommodated. So while “standard” decision theory is not exclusively consequentialist, it is not necessarily ethically neutral. Moreover, (...) even if our decision-theoretic models get the right answers vis-`a-vis morally correct action, the question remains as to whether the motivation for the non-consequentialist theories and the psychological processes of the agents who subscribe to those ethical theories are lost or poorly represented in the resulting models. (shrink)

Stanford’s argument against scientific realism focuses on theories, just as many earlier arguments from inconceivability have. However, there are possible arguments against scientific realism involving unconceived (or inconceivable) entities of different types: observations, models, predictions, explanations, methods, instruments, experiments, and values. This paper charts such arguments. In combination, they present the strongest challenge yet to scientific realism.

It is widely believed that the so-called knowledge account of assertion best explains why sentences such as “It’s raining in Paris but I don’t believe it” and “It’s raining in Paris but I don’t know it” appear odd to us. I argue that the rival rational credibility account of assertion explains that fact just as well. I do so by providing a broadly Bayesian analysis of the said type of sentences which shows that such sentences cannot express rationally held beliefs. (...) As an interesting aside, it will be seen that these sentences also harbor a lesson for Bayesian epistemology itself. (shrink)

The Dutch Book argument, like Route 66, is about to turn 80. It is arguably the most celebrated argument for subjective Bayesianism. Start by rejecting the Cartesian idea that doxastic attitudes are ‘all-or-nothing’; rather, they are far more nuanced degrees of belief, for short credences, susceptible to fine-grained numerical measurement. Add a coherentist assumption that the rationality of a doxastic state consists in its internal consistency. The remaining problem is to determine what consistency of credences amounts to. The Dutch Book (...) argument, in a nutshell, says that if your credences do not obey the probability calculus, you are ‘incoherent’—susceptible to sure losses at the hands of a ‘Dutch Bookie’—and thus irrational. Conclusion: rationality requires your credences to obey the probability calculus. And like Route 66, the fortunes of the Dutch Book argument have been mixed. Opinions on the argument are sharply divided. The list of its proponents is quite a ‘who’s who’ of philosophers of probability; they include de Finetti (1937, 1980), Carnap (1950, 1962, and more fully, 1955), Kemeny (1955), Lehman (1955), Shimony (1955), Adams (1962), Mellor (1971), Rosenkrantz (1981), van Fraassen (1989), Jeffrey (1983, 1992). (shrink)

Negligence is a problematic basis for being morally blamed and punished for having caused some harm, because in such cases there is no choice to cause or allow—or risk causing or allowing—such harm to occur. The standard theories as to why inadvertent risk creation can be blameworthy despite the lack of culpable choice are that in such cases there is blame for: (1) an unexercised capacity to have adverted to the risk; (2) a defect in character explaining why one did (...) not advert to the risk; (3) culpably acquiring or failing to rid oneself of these defects of character at some earlier time; (4) flawed use of those practical reasoning capacities that make one the person one is; or (5) chosen violation of per se rules about known precautions. Although each of these five theories can justify blame in some cases of negligence, none can justify blame in all cases intuitively thought to be cases of negligence, nor can any of these five theories show why inadvertent creation of an unreasonable risk, pure and simple, can be blameworthy. (shrink)

My purpose in this chapter is to survey some of the principal approaches to inductive inference in the philosophy of science literature. My first concern will be the general principles that underlie the many accounts of induction in this literature. When these accounts are considered in isolation, as is more commonly the case, it is easy to overlook that virtually all accounts depend on one of very few basic principles and that the proliferation of accounts can be understood as efforts (...) to ameliorate the weaknesses of those few principles. In the earlier sections, I will lay out three inductive principles and the families of accounts of induction they engender. In later sections I will review standard problems in the philosophical literature that have supported some pessimism about induction and suggest that their import has been greatly overrated. In the final sections I will return to the proliferation of accounts of induction that frustrates efforts at a final codification. I will suggest that this proliferation appears troublesome only as long as we expect inductive inference to be subsumed under a single formal theory. If we adopt a material theory of induction in which individual inductions are licensed by particular facts that prevail only in local domains, then the proliferation is expected and not problematic. (shrink)

I describe a realist, ontologically objective interpretation of probability, "far-flung frequency (FFF) mechanistic probability". FFF mechanistic probability is defined in terms of facts about the causal structure of devices and certain sets of frequencies in the actual world. Though defined partly in terms of frequencies, FFF mechanistic probability avoids many drawbacks of well-known frequency theories and helps causally explain stable frequencies, which will usually be close to the values of mechanistic probabilities. I also argue that it's a virtue rather than (...) a failing of FFF mechanistic probability that it does not define single-case chances, and compare some aspects of my interpretation to a recent interpretation proposed by Strevens. (shrink)

GRW Theory postulates a stochastic mechanism assuring that every so often the wave function of a quantum system is `hit', which leaves it in a localised state. How are we to interpret the probabilities built into this mechanism? GRW theory is a firmly realist proposal and it is therefore clear that these probabilities are objective probabilities (i.e. chances). A discussion of the major theories of chance leads us to the conclusion that GRW probabilities can be understood only as either single (...) case propensities or Humean objective chances. Although single case propensities have some intuitive appeal in the context of GRW theory, on balance it seems that Humean objective chances are preferable on conceptual grounds because single case propensities suffer from various well know problems such as unlimited frequency tolerance and lack of a rationalisation of the principal principle. (shrink)

The Paradox of the Ravens (a.k.a,, The Paradox of Confirmation) is indeed an old chestnut. A great many things have been written and said about this paradox and its implications for the logic of evidential support. The first part of this paper will provide a brief survey of the early history of the paradox. This will include the original formulation of the paradox and the early responses of Hempel, Goodman, and Quine. The second part of the paper will describe attempts (...) to resolve the paradox within a Bayesian framework, and show how to improve upon them. This part begins with a discussion of how probabilistic methods can help to clarify the statement of the paradox itself. And it describes some of the early responses to probabilistic explications. We then inspect the assumptions employed by traditional (canonical) Bayesian approaches to the paradox. These assumptions may appear to be overly strong. So, drawing on weaker assumptions, we formulate a new-and-improved Bayesian confirmation-theoretic resolution of the Paradox of the Ravens. (shrink)

Sometimes different partitions of the same space each seem to divide that space into propositions that call for equal epistemic treatment. Famously, equal treatment in the form of equal point-valued credence leads to incoherence. Some have argued that equal treatment in the form of equal interval-valued credence solves the puzzle. This paper shows that, once we rule out intervals with extreme endpoints, this proposal also leads to incoherence.

When do we agree? The answer might once have seemed simple and obvious; we agree that p when we each believe that p. But from a formal epistemological perspective, where degrees of belief are more fundamental than beliefs, this answer is unsatisfactory. On the one hand, there is reason to suppose that it is false; degrees of belief about p might differ when beliefs simpliciter on p do not. On the other hand, even if it is true, it is too (...) vague; for what it is to believe simpliciter ought to be explained in terms of degrees of belief. This paper presents several possible notions of agreement, and corresponding notions of disagreement. It indicates how the findings are fruitful for the epistemology of disagreement, with special reference to the notion of epistemic peerhood. (shrink)

Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think instead (...) that a deeper understanding of cancer can be achieved by means of more theoretical work, rather than by merely accumulating more data. To support our thesis, we introduce the analytic view of theory development, which rests on the concept of plausibility, and make clear in what sense plausibility and probability are distinct concepts. Then, the concept of plausibility is used to point out the ineliminable role played by the epistemic subject in the development of statistical tools and in the process of theory assessment. We then move to address a central issue in cancer research, namely the relevance of computational tools developed by bioinformaticists to detect driver mutations in the debate between the two main rival theories of carcinogenesis. Finally, we briefly extend our considerations on the role that plausibility plays in evidence amalgamation from cancer research to the more general issue of the divergences between frequentists and Bayesians in the philosophy of medicine and statistics. We argue that taking into account plausibility-based considerations can lead to clarify some epistemological shortcomings that afflict both these perspectives. (shrink)

Bayes' Theorem is a simple mathematical formula used for calculating conditional probabilities. It figures prominently in subjectivist or Bayesian approaches to epistemology, statistics, and inductive logic. Subjectivists, who maintain that rational belief is governed by the laws of probability, lean heavily on conditional probabilities in their theories of evidence and their models of empirical learning. Bayes' Theorem is central to these enterprises both because it simplifies the calculation of conditional probabilities and because it clarifies significant features of subjectivist position. Indeed, (...) the Theorem's central insight — that a hypothesis is confirmed by any body of data that its truth renders probable — is the cornerstone of all subjectivist methodology. (shrink)

We characterize access to empirical objects in biology from a theoretical perspective. Unlike objects in current physical theories, biological objects are the result of a history and their variations continue to generate a history. This property is the starting point of our concept of measurement. We argue that biological measurement is relative to a natural history which is shared by the different objects subjected to the measurement and is more or less constrained by biologists. We call symmetrization the theoretical and (...) often concrete operation which leads to considering biological objects as equivalent in a measurement. Last, we use our notion of measurement to analyze research strategies. Some strategies aim to bring biology closer to the epistemology of physical theories, by studying objects as similar as possible, while others build on biological diversity. (shrink)

Evolutionary theory (ET) is teeming with probabilities. Probabilities exist at all levels: the level of mutation, the level of microevolution, and the level of macroevolution. This uncontroversial claim raises a number of contentious issues. For example, is the evolutionary process (as opposed to the theory) indeterministic, or is it deterministic? Philosophers of biology have taken different sides on this issue. Millstein (1997) has argued that we are not currently able answer this question, and that even scientific realists ought to remain (...) agnostic concerning the determinism or indeterminism of evolutionary processes. If this argument is correct, it suggests that, whatever we take probabilities in ET to be, they must be consistent with either determinism or indeterminism. This raises some interesting philosophical questions: How should we understand the probabilities used in ET? In other words, what is meant by saying that a certain evolutionary change is more or less probable? Which interpretation of probability is the most appropriate for ET? I argue that the probabilities used in ET are objective in a realist sense, if not in an indeterministic sense. Furthermore, there are a number of interpretations of probability that are objective and would be consistent with ET under determinism or indeterminism. However, I argue that evolutionary probabilities are best understood as propensities of population-level kinds. (shrink)

I argue that the propensity interpretation of fitness, properly understood, not only solves the explanatory circularity problem and the mismatch problem, but can also withstand the Pandora’s box full of problems that have been thrown at it. Fitness is the propensity (i.e., probabilistic ability, based on heritable physical traits) for organisms or types of organisms to survive and reproduce in particular environments and in particular populations for a specified number of generations; if greater than one generation, “reproduction” includes descendants of (...) descendants. Fitness values can be described in terms of distributions of propensities to produce varying number of offspring and can be modeled for any number of generations using computer simulations, thus providing both predictive power and a means for comparing the fitness of different phenotypes. Fitness is a causal concept, most notably at the population level, where fitness differences are causally responsible for differences in reproductive success. Relative fitness is ultimately what matters for natural selection. (shrink)

Objective Bayesianism has been criticised on the grounds that objective Bayesian updating, which on a finite outcome space appeals to the maximum entropy principle, differs from Bayesian conditionalisation. The main task of this paper is to show that this objection backfires: the difference between the two forms of updating reflects negatively on Bayesian conditionalisation rather than on objective Bayesian updating. The paper also reviews some existing criticisms and justifications of conditionalisation, arguing in particular that the diachronic Dutch book justification fails (...) because diachronic Dutch book arguments are subject to a reductio: in certain circumstances one can Dutch book an agent however she changes her degrees of belief . One may also criticise objective Bayesianism on the grounds that its norms are not compulsory but voluntary, the result of a stance. It is argued that this second objection also misses the mark, since objective Bayesian norms are tied up in the very notion of degrees of belief. (shrink)

In this paper I combine the dynamic epistemic logic ofGerbrandy (1999) with the probabilistic logic of Fagin and Halpern (1994). The resultis a new probabilistic dynamic epistemic logic, a logic for reasoning aboutprobability, information, and information change that takes higher orderinformation into account. Probabilistic epistemic models are defined, and away to build them for applications is given. Semantics and a proof systemis presented and a number of examples are discussed, including the MontyHall Dilemma.

In this paper, we pursue three general aims: (I) We will define a notion of fundamental opacity and ask whether it can be found in High Energy Physics (HEP), given the involvement of machine learning (ML) and computer simulations (CS) therein. (II) We identify two kinds of non-fundamental, contingent opacity associated with CS and ML in HEP respectively, and ask whether, and if so how, they may be overcome. (III) We address the question of whether any kind of opacity, contingent (...) or fundamental, is unique to ML or CS, or whether they stand in continuity to kinds of opacity associated with other scientific research. (shrink)

Single-case and long-run propensity theories are among the main objective interpretations of probability. There have been various objections to these theories, e.g. that it is difficult to explain why propensities should satisfy the probability axioms and, worse, that propensities are at odds with these axioms, that the explication of propensities is circular and accordingly not informative, and that single-case propensities are metaphysical and accordingly non-scientific. We consider various propensity theories of probability and their prospects in light of these objections. We (...) argue that while propensity theories face challenges, these challenges do not undermine their validity as prospective interpretations of probability in science. (shrink)

Proponents of Bayesian confirmation theory believe that they have the solution to a significant, recalcitrant problem in philosophy of science. It is the identification of the logic that governs evidence and its inductive bearing in science. That is the logic that lets us say that our catalog of planetary observations strongly confirms Copernicus’ heliocentric hypothesis; or that the fossil record is good evidence for the theory of evolution; or that the 3oK cosmic background radiation supports big bang cosmology. The definitive (...) solution to this problem would be a significant achievement. The problem is of central importance to philosophy of science, for, in the end, what distinguishes science from myth making is that we have good evidence for the content of science, or at least of mature sciences, whereas myths are evidentially ungrounded fictions. The core ideas shared by all versions of Bayesian confirmation theory are, at a good first approximation, that a scientist’s beliefs are or should conform to a probability measure; and that the incorporation of new evidence is through conditionalization using Bayes’ theorem. While the burden of this chapter will be to inventory why critics believe this theory may not be the solution after all, it is worthwhile first to summarize here the most appealing virtues of this simple account. There are three. First, the theory reduces the often nebulous notion of a logic of.. (shrink)

The Preface Paradox has led many philosophers to believe that, if it isassumed that high probability is necessary for rational acceptability, the principleaccording to which rational acceptability is closed under conjunction (CP)must be abandoned. In this paper we argue that the paradox is far less damaging to CP than is generally believed. We describe how, given certain plausibleassumptions, in a large class of cases in which CP seems to lead tocontradiction, it does not do so after all. A restricted version (...) of CP canthus be maintained. (shrink)

Some of the information we receive comes to us in an explicitly conditional form. It is an open question how to model the accommodation of such information in a Bayesian framework. This paper presents data suggesting that there may be no strictly Bayesian account of updating on conditionals. Specifically, the data seem to indicate that such updating at least sometimes proceeds on the basis of explanatory considerations, which famously have no home in standard Bayesian epistemology. The paper also proposes a (...) still broadly Bayesian model of updating on conditionals that explicitly factors in explanation. The model is shown to have clear empirical content and thus to be open to empirical testing. (shrink)

What meaning does epidemiological evidence have for the individual? In evidence-based medicine, epidemiological evidence measures the patient’s risk of the outcome or the change in risk due to an intervention. The patient’s risk is commonly understood as an individual probability. The problem of understanding epidemiological evidence and risk thus becomes the challenge of interpreting individual patient probabilities. I argue that the patient’s risk is interpreted ontically, as a propensity. After exploring formidable problems with this interpretation in the medical context, I (...) propose an epistemic reinterpretation of individual patient probabilities as credences. On this view, epidemiological evidence informs medical uncertainty. (shrink)

Information, entropy, probability: these three terms are closely interconnected in the prevalent understanding of statistical mechanics, both when this field is taught to students at an introductory level and in advanced research into the field’s foundations. This paper examines the interconnection between these three notions in light of recent research in the foundations of statistical mechanics. It disentangles these concepts and highlights their differences, at the same time explaining why they came to be so closely linked in the literature. In (...) the literature the term ‘information’ is often linked to entropy and probability in discussions of Maxwell’s Demon and its attempted exorcism by the Landauer-Bennett thesis, and in analyses of the spin echo experiments. The direction taken in the present paper is a different one. Here we discuss the statistical mechanical underpinning of the notions of probability and entropy, and this constructive approach shows that information plays no fundamental role in these concepts, although it can be conveniently used in a sense that we shall specify. (shrink)

There has been a significant interest in the recent literature in developing a solution to the problem of theory choice which is both normative and descriptive, but agent-based rather than rule-based, originating from Pierre Duhem’s notion of ‘good sense’. In this paper we present the properties Duhem attributes to good sense in different contexts, before examining its current reconstructions advanced in the literature and their limitations. We propose an alternative account of good sense, seen as promoting social consensus in science, (...) and show that it is superior to its rivals in two respects: it is more faithful to Duhemian good sense, and it cashes out the effect that virtues have on scientific progress. We then defend the social consensus account against objections that highlight the positive role of diversity and division of labour in science. (shrink)

In this thesis, I give a metascientific account of causality in medicine. I begin with two historical cases of causal discovery. These are the discovery of the causation of Burkitt’s lymphoma by the Epstein-Barr virus, and of the various viral causes suggested for cervical cancer. These historical cases then support a philosophical discussion of causality in medicine. This begins with an introduction to the Russo- Williamson thesis (RWT), and discussion of a range of counter-arguments against it. Despite these, I argue (...) that the RWT is historically workable, given a small number of modifications. I then expand Russo and Williamson’s account. I first develop their suggestion that causal relationships in medicine require some kind of evidence of mechanism. I begin with a number of accounts of mechanisms and produce a range of consensus features of them. I then develop this consensus position by reference to the two historical case studies with an eye to their operational competence. In particular, I suggest that it is mechanistic models and their representations which we are concerned with in medicine, rather than the mechanism as it exists in the world. -/- I then employ these mechanistic models to give an account of the sorts of evidence used in formulating and evaluating causal claims. Again, I use the two human viral oncogenesis cases to give this account. I characterise and distinguish evidence of mechanism from evidence of difference-making, and relate this to mechanistic models. I then suggest the relationship between types of evidence presents us with a means of tackling the reference-class problem. This sets the scene for the final chapter. Here, I suggest the manner in which these two different classes of evidence become integrated is also reflected in the way that developing research programmes change as their associated causal claims develop. (shrink)