The heated debates and severe conflicts between the atomists and the anti-atomists of the latter half of the nineteenth century are well known to the historian of science. The position of Dmitrii Ivanovich Mendeleev towards these nineteenth century debates on atomism will be studied in this paper. A first attempt will thus be offered to reconcile Mendeleev’s seemingly contradictory comments and ambiguous standpoints into one coherent view.

LEITE (Fábio Rodrigo) – STOFFEL (Jean-François), Introduction (pp. 3-6). BARRA (Eduardo Salles de O.) – SANTOS (Ricardo Batista dos), Duhem’s analysis of Newtonian method and the logical priority of physics over metaphysics (pp. 7-19). BORDONI (Stefano), The French roots of Duhem’s early historiography and epistemology (pp. 20-35). CHIAPPIN (José R. N.) – LARANJEIRAS (Cássio Costa), Duhem’s critical analysis of mecha­ni­cism and his defense of a formal conception of theoretical phy­sics (pp. 36-53). GUEGUEN (Marie) – PSILLOS (Stathis), Anti-­scepticism and epistemic humility (...) in Pierre Duhem’s philosophy of science (pp. 54-72). LISTON (Michael), Duhem : images of science, historical continuity, and the first crisis in physics (pp. 73-84). MAIOCCHI (Roberto), Duhem in pre-war Italian philos­ophy : the reasons of an absence (pp. 85-92). HERNÁNDEZ MÁRQUEZ (Víctor Manuel), Was Pierre Duhem an «esprit de finesse» ? (pp. 93-107). NEEDHAM (Paul), Was Duhem justified in not distinguishing between physical and chemical atomism ? (pp. 108-111). OLGUIN (Roberto Estrada), «Bon sens» and «noûs» (pp. 112-126). OLIVEIRA (Amelia J.), Duhem’s legacy for the change in the historiography of science : An analysis based on Kuhn’s writings (pp. 127-139). PRÍNCIPE (João), Poincaré and Duhem : Resonances in their first epistemological reflec­tions (pp. 140-156). MONDRAGON (Damián Islas), Book review of «Pierre Duhem : entre física y metafísica» (pp. 157-159). STOFFEL (Jean-François), Book review of P. Duhem : «La théorie physique : son objet, sa structure» / edit. by S. Roux (pp. 160-162). STOFFEL (Jean-François), Book review of St. Bordoni : «When historiography met epistemology» (pp. 163-165). (shrink)

In this paper, I discuss the use made by Aristotle of the term “element” when dealing with the atomist theory of Leucippus and Democritus. My goal is to verify which aspects of the atomist theory play the role of elements according to the definitions of Aristotle, who seems to have certain expectations regarding what can be designated as elements in the strict sense. One of them is the possibility of reciprocal transformation, the so-called “generation of elements”, which is the (...) class='Hi'>chemical aspect at the level of the simple bodies that makes change possible at the level of sense-perceived bodies. Furthermore, I evaluate whether it is possible to find and whether it is adequate to speak of the presence of the four elements – fire, air, water and earth – in the atomist doctrine. (shrink)

Between 1653 and 1655 Margaret Cavendish makes a radical transition in her theory of matter, rejecting her earlier atomism in favour of an infinitely-extended and infinitely-divisible material plenum, with matter being ubiquitously self-moving, sensing, and rational. It is unclear, however, if Cavendish can actually dispense of atomism. One of her arguments against atomism, for example, depends upon the created world being harmonious and orderly, a premise Cavendish herself repeatedly undermines by noting nature’s many disorders. I argue that (...) her supposed difficulties with atomism expose a deeper tension in her work between two fundamental metaphysical commitments each of which has substantial philosophical support: her monist theory of the material world (which maintains that there exists just one natural substance which is the single principal cause) and her occasional theory of causation (which requires multiple finite principal causes in nature -- causes that might be considered individual substances). Her monism undermines atomism while her theory of occasional cause seems to rest on a conception of nature that would be especially friendly to atomism. I argue further that we can solve this tension within a Cavendishian framework in such a way as to preserve her theory of causation and her monism, but that this solution depends upon our taking her monism in a particular (and weak) form. I finally note that we can best make sense of her unique and interesting form of monism by acknowledging her social-political motivations in addition to her motivations in natural philosophy. (shrink)

According to anti-atomism, we represent color properties (e.g., red) in virtue of representing color relations (e.g., redder than). I motivate anti-atomism with a puzzle involving a series of pairwise indistinguishable chips. I then develop two versions of anti-atomism.

Jerrold J. Katz often explained his semantic theory by way of an analogy with physical atomism and an attendant analogy with chemistry. In this chapter, I track the origin and uses of these analogies by Katz, both in explaining and defending his decompositional semantic theory, through the various phases of his work throughout his career.

Biological atomism postulates that all life is composed of elementary and indivisible vital units. The activity of a living organism is thus conceived as the result of the activities and interactions of its elementary constituents, each of which individually already exhibits all the attributes proper to life. This paper surveys some of the key episodes in the history of biological atomism, and situates cell theory within this tradition. The atomistic foundations of cell theory are subsequently dissected and discussed, (...) together with the theory’s conceptual development and eventual consolidation. This paper then examines the major criticisms that have been waged against cell theory, and argues that these too can be interpreted through the prism of biological atomism as attempts to relocate the true biological atom away from the cell to a level of organization above or below it. Overall, biological atomism provides a useful perspective through which to examine the history and philosophy of cell theory, and it also opens up a new way of thinking about the epistemic decomposition of living organisms that significantly departs from the physicochemical reductionism of mechanistic biology. (shrink)

The original conception of atomism suggests “atoms”, which cannot be divided more into composing parts. However, the name “atom” in physics is reserved for entities, which can be divided into electrons, protons, neutrons and other “elementary particles”, some of which are in turn compounded by other, “more elementary” ones. Instead of this, quantum mechanics is grounded on the actually indivisible quanta of action limited by the fundamental Planck constant. It resolves the problem of how both discrete and continuous (even (...) smooth) to be described uniformly and invariantly in thus. Quantum mechanics can be interpreted in terms of quantum information. Qubit is the indivisible unit (“atom”) of quantum information. The imagery of atomism in modern physics moves from atoms of matter (or energy) via “atoms” (quanta) of action to “atoms” (qubits) of quantum information. This is a conceptual shift in the cognition of reality to terms of information, choice, and time. (shrink)

There are at least three vaguely atomistic principles that have come up in the literature, two explicitly and one implicitly. First, standard atomism is the claim that everything is composed of atoms, and is very often how atomism is characterized in the literature. Second, superatomism is the claim that parthood is well-founded, which implies that every proper parthood chain terminates, and has been discussed as a stronger alternative to standard atomism. Third, there is a principle that lies (...) between these two theses in terms of its relative strength: strong atomism, the claim that every maximal proper parthood chain terminates. Although strong atomism is equivalent to superatomism in classical extensional mereology, it is strictly weaker than it in strictly weaker systems in which parthood is a partial order. And it is strictly stronger than standard atomism in classical extensional mereology and, given the axiom of choice, in such strictly weaker systems as well. Though strong atomism has not, to my knowledge, been explicitly identified, Shiver appears to have it in mind, though it is unclear whether he recognizes that it is not equivalent to standard atomism in each of the mereologies he considers. I prove these logical relationships which hold amongst these three atomistic principles, and argue that, whether one adopts classical extensional mereology or a system strictly weaker than it in which parthood is a partial order, standard atomism is a more defensible addition to one’s mereology than either of the other two principles, and it should be regarded as the best formulation of the atomistic thesis. (shrink)

This chapter explores whether chemical castration can be justified as a form of criminal punishment. The author argues that castration via the drug medroxyprogesterone acetate (MPA), or some similar drug, does not achieve the punishment aims of retribution, deterrence, or incapacitation, but might serve as punishment in the form of rehabilitative treatment. However, current U.S. chemical castration statutes are too broad to be justified as rehabilitative. The state is warranted in targeting psychological states in criminal defendants for rehabilitative (...) treatment where such states (a) act as a primary cause of a criminal offender’s crime and (b) give rise to extraordinary worries that the offender will recidivate. Current statutes qualify criminal offenders for castration who do not have overwhelming sexual urges or other psychological states causally related to their crime that may be treated with MPA. Thus, even assuming the efficacy of MPA, such statutes are unjustifiable because they apply chemical castration to offenders for whom castration will have no rehabilitative effect. (shrink)

There is a persisting debate about what chemical bonds are and whether they exist. I argue that chemical bonds are real patterns of interactions between subatomic particles. This proposal resolves the problems raised in the context of existing understandings of the chemical bond and provides a novel way to defend the reality of chemical bonds.

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be (...) made more complicated in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

An essay examining logical atomism as it arises in Russell and the early Wittgenstein.

Long-standing neglect of the chemical senses in the philosophy of perception is due, mostly, to their being regarded as ‘lower’ senses. Smell, taste, and chemically irritated touch are thought to produce mere bodily sensations. However, empirically informed theories of perception can show how these senses lead to perception of objective properties, and why they cannot be treated as special cases of perception modelled on vision. The senses of taste, touch, and smell also combine to create unified perceptions of flavour. (...) The nature of these multimodal experiences and the character of our awareness of them puts pressure on the traditional idea that each episode of perception goes one or other of the five senses. Thus, the chemical senses, far from being peripheral to the concerns of the philosophy of perception, may hold important clues to the multisensory nature of perception in general. (shrink)

This book examines the way in which Robert Boyle seeks to accommodate his complex chemical philosophy within the framework of a mechanistic theory of matter. More specifically, the book proposes that Boyle regards chemical qualities as properties that emerged from the mechanistic structure of chymical atoms. Within Boyle’s chemical ontology, chymical atoms are structured concretions of particles that Boyle regards as chemically elementary entities, that is, as chemical wholes that resist experimental analysis. Although this interpretation of (...) Boyle’s chemical philosophy has already been suggested by other Boyle scholars, the present book provides a sustained philosophical argument to demonstrate that, for Boyle, chemical properties are dispositional, relational, emergent, and supervenient properties. This argument is strengthened by a detailed mereological analysis of Boylean chymical atoms that establishes the kind of theory of wholes and parts that is most consistent with an emergentist conception of chemical properties. The emergentist position that is being attributed to Boyle supports his view that chemical reactions resist direct explanation in terms of the mechanistic properties of fundamental particles, as well as his position regarding the scientific autonomy of chymistry from mechanics and physics. (shrink)

The aim of this paper is to examine the theoretical architecture of semantic atomism and its consequences with respect to natural language. In particular, it looks to explore the notion of possible concepts using the fundamental distinction between simple and complex concepts and expressions in Jerry Fodor’s atomism. The distinction is exploited to produce an unusual type of concept referred to as a correlate, which effectively mirrors complex concepts while maintaining a distinct underlying structure. Though harmless in and (...) of themselves, their presence in the context of polymorphemic expressions suggests that atomism harbors a tacit and unintuitive form of polysemy that is problematic in its own right and that leads to other complications, some of which may be demonstrated on the example of communication. These issues are tied to the way atomism is structured, and although they seem to have gone largely unnoticed, they appear to bear negatively on the adequacy of atomism where natural language is concerned. (shrink)

We are immersed within an odorous sea of chemical currents that we parse into individual odors with complex structures. Odors have been posited as determined by the structural relation between the molecules that compose the chemical compounds and their interactions with the receptor site. But, naturally occurring smells are parsed from gaseous odor plumes. To give a comprehensive account of the nature of odors the chemosciences must account for these large distributed entities as well. We offer a focused (...) review of what is known about the perception of odor plumes for olfactory navigation and tracking, which we then connect to what is known about the role odorants play as properties of the plume in determining odor identity with respect to odor quality. We end by motivating our central claim that more research needs to be conducted on the role that odorants play within the odor plume in determining odor identity. (shrink)

In this paper, I will try to look at Leibniz from the topos of Indian philosophy. François Jullien called such a strategy “dépayser la pensée” – to withdraw an idea from its familiar environment and to see it through the lens of a different culture. “Read Confucius to better understand Plato.” I am referring to Indian philosophy, especially to some Buddhist systems, in order to highlight certain aspects of Leibniz’s mode of thinking, that I define as “atomistic approach”.

Functional decomposition is an important goal in the life sciences, and is central to mechanistic explanation and explanatory reduction. A growing literature in philosophy of science, however, has challenged decomposition-based notions of explanation. ‘Holists’ posit that complex systems exhibit context-sensitivity, dynamic interaction, and network dependence, and that these properties undermine decomposition. They then infer from the failure of decomposition to the failure of mechanistic explanation and reduction. I argue that complexity, so construed, is only incompatible with one notion of decomposition, (...) which I call ‘atomism’, and not with decomposition writ large. Atomism posits that function ascriptions must be made to parts with minimal reference to the surrounding system. Complexity does indeed falsify atomism, but I contend that there is a weaker, ‘contextualist’ notion of decomposition that is fully compatible with the properties that holists cite. Contextualism suggests that the function of parts can shift with external context, and that interactions with other parts might help determine their context-appropriate functions. This still admits of functional decomposition within a given context. I will give examples based on the notion of oscillatory multiplexing in systems neuroscience. If contextualism is feasible, then holist inferences are faulty—one cannot infer from the presence of complexity to the failure of decomposition, mechanism, and reductionism. (shrink)

While holism and atomism are often treated as mutually exclusive approaches to semantic theory, the apparent tension between the two usually results from running together distinct levels of semantic explanation. In particular, there is no reason why one can’t combine an atomistic conception of what the semantic values of our words are (one’s “descriptive semantics”), with a holistic explanation of why they have those values (one’s “foundational semantics”). Most objections to holism can be shown to apply only to holistic (...) version of descriptive semantics, and do not tell against any sorts of holistic foundational semantics. As Davidson’s work will be used to illustrate, by clearly distinguishing foundational and descriptive semantics, one can capture the most appealing features of both holism and atomism. (shrink)

The chemical characterization of the substance responsible for the phenomenon of “transformation” of pneumococci was presented in the now famous 1944 paper by Avery, MacLeod, and McCarty. Reception of this work was mixed. Although interpreting their results as evidence that deoxyribonucleic acid (DNA) is the molecule responsible for genetic changes was, at the time, controversial, this paper has been retrospectively celebrated as providing such evidence. The mixed and changing assessment of the evidence presented in the paper was due to (...) the work’s interpretive flexibility – the evidence was interpreted in various ways, and such interpretations were justified given the neophytic state of molecular biology and methodological limitations of Avery’s transformation studies. I argue that the changing context in which the evidence presented by Avery’s group was interpreted partly explains the vicissitudes of the assessments of the evidence. Two less compelling explanations of the reception are a myth-making account and an appeal to the wartime historical context of its publication. (shrink)

The practice of medicine frequently involves the unconsented restriction of liberty. The reasons for unilateral liberty restrictions are typically that being confined, strapped down, or sedated are necessary to prevent the person from harming themselves or others. In this paper, we target the ethics of chemical restraints, which are medications that are used to intentionally restrict the mental states associated with the unwanted behaviors, and are typically not specifically indicated for the condition for which the patient is being treated. (...) Specifically, we aim to identify the conditions under which chemical restraints are ethically permissible. It is wrong to assume that what is morally true of physical restraints is also true of chemical restraints. Our aim is thus to identify the conditions under which chemical restraints are permissible while distinguishing these conditions from those of the application of physical restraints. (shrink)

Jacques Monod (1971) argued that certain molecular processes rely critically on the property of chemical arbitrariness, which he claimed allows those processes to “transcend the laws of chemistry”. It seems natural, as some philosophers have done, to interpret this in modal terms: a biological relationship is chemically arbitrary if it is possible, within the constraints of chemical “law”, for that relationship to have been otherwise than it is. But while modality is certainly important for understanding chemical arbitrariness, (...) understanding its biological role also requires an account of the concrete causal-functional features that distinguish arbitrary from non-arbitrary phenomena. In this paper I elaborate on this under-emphasised aspect by offering a general account of these features: arbitrary relations are instantiated by mechanisms that involve molecular adapters, which causally couple two properties or processes which would otherwise be uncorrelated. Additionally, adapters work by acting as intermediate rather than cooperating causes. (shrink)

Many philosophers reject the view that well-being over a lifetime is simply an aggregation of well-being at every moment of one's life, and thus they reject theories of well-being like hedonism and concurrentist desire satisfactionism. They raise concerns that such a view misses the importance of the relationships between moments in a person's life or the role narratives play in a person's well-being. In this article, we develop an atomist meta-theory of well-being, according to which the prudential value of a (...) life depends solely on the prudential value of each moment of that life. This is a general account of momentary well-being that can capture different features of well-being that standard atomistic accounts fail to capture, thus allowing for the possibility of an atomism that is compatible with a variety of well-being theories. Contrary to many criticisms leveled against momentary well-being, this well-being atomism captures all of the important features of well-being. (shrink)

The aim of my paper is to describe and evaluate different conceptions of holism in Ludwig Wittgenstein’s Tractatus Logico-Philosophicus. I distinguish three readings of holistic elements in this work: i) Minimal Holism (E. Anscombe, M. Black, D. Pears); ii) Moderate Holism (J. Conant, C. Diamond, G. Ryle); and iii) Radical Holism (G. Bar-Elli, M. Kremer, P. Livingston). The conclusion is that the most viable option is Moderate Holism since it embraces the logico-syntactical notion of use, rejects an anachronistic interpretation of (...) Tractatarian ontology and allows us to see that the holistic elements are complementary to the initial atomism of the work. Moreover, I point to the consequences of the topic for the overall reading of Wittgenstein’s early and late work. (shrink)

Ksenija Atanasijevic was not only the first female lecturer at the University of Belgrade but also the first expert in the Ancient Greek Philosophy. In this paper, I will not engage with all of her writings about Ancient Greek thought. Instead, I will place the emphasis on her interpretation of Epicurus, because her best and most profound works are dedicated to his philosophy, including her book on the Epicurus’s atomism written in French under the title L’atomisme d’Épicure. I will (...) critically discuss the consistency, plausibility, and relevance both of her interpretations of Epicurus, and his ethics and doctrine of minima. (shrink)

In The Conditions for Ethical Chemical Restraint, Crutchfield and Redinger (2024) propose ethical standards for the use of chemical restraints, which they consider normatively distinct from physica...

Francis Bacon’s theory of matter is a controversial topic among historians. I agree with the viewpoint, which suggests that although Bacon changed his views on atomism repeatedly, he never rejected it completely (Partington, Urbach, Gemelli). I will substantiate this interpretation by paying more attention to the usually neglected allegorical works and by investigating why Bacon changed his mind on atomism in his Novum organum. I shall reconstruct Bacon’s various opinions in chronological order to establish his final evaluation of (...) atomism and his reasons for it. Given that Bacon never embraced a matter theory identical with Greek atomism, I shall here define atomism in the broadest sense, as a corpuscular matter theory that posits final and indivisible particles. Following this semantic delimitation, two successive Baconian opinions will be distinguished: the first took the atom to constitute an ontological and causative-operational principle; the second deprived the atom of this causative-operational ability, but did not touch its ontological priority. At the same time, I will investigate the question concerning the coexistence of atomism and pneumatism in Bacon’s theory, a point that has been discussed in the influential interpretations by Kargon and Rees. I shall argue that Bacon did not regard these two doctrines as incompatible. (shrink)

This paper provides a new first cause argument by showing that atomism, i.e. the thesis that each composite object is composed of simple objects, together with causalism, understood in this paper as the thesis that every object is a cause or has a cause, logically imply the existence of a first cause if some additional general premises regarding the interplay between parthood, composition and causation are accepted. Thus it is shown that a commitment to atomism, causalism and the (...) additional premises result in a commitment to there being a first cause. (shrink)

The research is a comparative study of the atomic theories of Kanada and Democritus. Because of their pluralistic tendencies, emphasis on causality, their materialistic account of sense knowledge, and their attempt to explain the physical system by means of reduction to the configuration of its constitutive elements, both philosophers present an epistemological base that could accommodate scientific inquiry. Notwithstanding the early and expansive beginning of Indian atomism, modern scientific atomic theory traces its origin to Democritus. Through cross-cultural critical engagement (...) of parallel ideas between Kanada and Democritus, the paper aims to discover the common problems that they dealt with in order to further our understanding of the early history of atomic theory, to evaluate the relative merits and limitations of their proposed solutions, to resolve some difficulties that each account faces by appealing to the other, and to highlight their contributions to the emergence of atomic worldview. (shrink)

This study aims to shed light on the position of Imām al-Māturīdī (d. 333/944) on atomism. It consists of three sections. The first section will delineate some theories of matter along with the meaning of certain pertinent terms, which were widely accepted during al-Māturīdī’s time. The following section will discuss whether Imām al-Māturīdī understood such notions as body (jism), substance (jawhar), and accident (ʿaraḍ) within the frame of traditional Islamic atomism. Moreover, this section will give some information on (...) how al-Māturīdī approached the issues pertaining to physics and cosmology. The last section will cover the development of atomism in the Māturīdiyya kalām school after Imām al-Māturīdī. (shrink)

This paper is a study of a distinctively chemical notion of possibility. This is the notion of possibility that occurs in chemical discourses when chemists speak of the possibility or impossibility of achieving a given result through chemical means. This notion pertains to the possibility of processes, not of compounds, so it differs from the kind of chemical possibility mentioned in Wittgenstein's Philosophical Investigations or the kinds discussed in the literature on Putnam's Twin Earth argument. I (...) argue that this process-oriented notion of possibility cannot be reduced in a simple way to physical possibility, and that standard possible worlds semantics does not allow a natural analysis of this notion. I suggest an extension of possible worlds semantics that may overcome this limitation. I finish by pointing out some open questions about chemical possibility. (shrink)

Mereological nihilism is the philosophical position that there are no items that have parts. If there are no items with parts then the only items that exist are partless fundamental particles, such as the true atoms (also called philosophical atoms) theorized to exist by some ancient philosophers, some contemporary physicists, and some contemporary philosophers. With several novel arguments I show that mereological nihilism is the correct theory of reality. I will also discuss strong similarities that mereological nihilism has with empirical (...) results in quantum physics. And I will discuss how mereological nihilism vindicates a few other theories, such as a very specific theory of philosophical atomism, which I will call quantum abstract atomism. I will show that mereological nihilism also is an interpretation of quantum mechanics that avoids the problems of other interpretations, such as the widely known, metaphysically generated, quantum paradoxes of quantum physics, which ironically are typically accepted as facts about reality. I will also show why it is very surprising that mereological nihilism is not a widely held theory, and not the premier theory in philosophy. (shrink)

The testimonia concerning weight in early Greek atomism appear to contradict one another. Some reports assert that the atoms do have weight, while others outright deny weight as a property of the atoms. A common solution to this apparent contradiction divides the testimonia into two groups. The first group describes the atoms within a κόσμος, where they have weight; the second group describes the atoms outside of a κόσμος, where they are weightless. A key testimonium for proponents of this (...) solution is Aëtius 1.3.18. It apparently denies weight as a property of the atoms, and supposedly describes the atoms when they are outside of a κόσμος. I argue against this interpretive solution by demonstrating, first, that Aëtius 1.3.18 does not deny that weight is a property of the atoms. Second, I argue that the report does not describe the atoms when they are outside of a κόσμος. Although these are largely negative conclusions, I contend that we are not left without a solution to the present interpretive difficulty. Once our testimonia concerning weight in early Greek atomism are examined thoroughly, it is clear that there is no conflict among them. (shrink)

Nanotechnology, as with many technologies before it, places a strain on existing legislation and poses a challenge to all administrative agencies tasked with regulating technology-based products. It is easy to see how statutory schemes become outdated, as our ability to understand and affect the world progresses. In this article, we address the regulatory problems that nanotechnology posses for the Food and Drug Administration’s (FDA) classification structure for ‘‘drugs’’ and ‘‘devices.’’ The last major modification to these terms was in 1976, with (...) the enactment of the Medical Device Amendments. There are serious practical differences for a classification as a drug or device in terms of time to market and research. Drugs are classified, primarily, as acting by ‘‘chemical action.’’ We lay out some legal, philosophic, and scientific tools that serve to provide a useful, as well as legally and scientifically faithful, distinction between drugs and devices for the purpose of regulatory classification. These issues we raise are worth the consideration of anyone who is interested in the regulation of nano-products or other novel technologies. (shrink)

I argue that Descartes' Second Causal Proof of God in the Third Meditation evidences, and commits him to, the belief that time is "strongly discontinuous" -- that is, that there is actually a gap between each consecutive moment of time. Much of my article attempts to reconcile this interpretation, the "received view," with Descartes' statements about time, space, and matter in his other writings, including his correspondence with various philosophers.

I characterize and argue against the standard interpretation of logical atomism. The argument against this reading is historical: the standard interpretation of logical atomism (1) fails to explain how the view is inspired by nineteenth-century developments in mathematics, (2) fails to explain how logic is central to logical atomism, and (3) fails to explain how logical atomism is a revolutionary and new "scientific philosophy." In short, the standard interpretation is a bad history of logical atomism. (...) A novel interpretation of the view that repairs these difficulties is sketched in the concluding section. (shrink)

Contemporary philosophy and theoretical psychology are dominated by an acceptance of content-externalism: the view that the contents of one's mental states are constitutively, as opposed to causally, dependent on facts about the external world. In the present work, it is shown that content-externalism involves a failure to distinguish between semantics and pre-semantics---between, on the one hand, the literal meanings of expressions and, on the other hand, the information that one must exploit in order to ascertain their literal meanings. It is (...) further shown that, given the falsity of content-externalism, the falsity of the Computational Theory of Mind (CTM) follows. It is also shown that CTM involves a misunderstanding of terms such as "computation," "syntax," "algorithm," and "formal truth." Novel analyses of the concepts expressed by these terms are put forth. These analyses yield clear, intuition-friendly, and extensionally correct answers to the questions "what are propositions?, "what is it for a proposition to be true?", and "what are the logical and psychological differences between conceptual (propositional) and non-conceptual (non-propositional) content?" Naively taking literal meaning to be in lockstep with cognitive content, Burge, Salmon, Falvey, and other semantic externalists have wrongly taken Kripke's correct semantic views to justify drastic and otherwise contraindicated revisions of commonsense. (Salmon: What is non-existent exists; at a given time, one can rationally accept a proposition and its negation. Burge: Somebody who is having a thought may be psychologically indistinguishable from somebody who is thinking nothing. Falvey: somebody who rightly believes himself to be thinking about water is psychologically indistinguishable from somebody who wrongly thinks himself to be doing so and who, indeed, isn't thinking about anything.) Given a few truisms concerning the differences between thought-borne and sentence-borne information, the data is easily modeled without conceding any legitimacy to any one of these rationality-dismantling atrocities. (It thus turns out, ironically, that no one has done more to undermine Kripke's correct semantic points than Kripke's own followers!). (shrink)

In a number of papers and in his recent book, Is Water H₂O? Evidence, Realism, Pluralism (2012), Hasok Chang has argued that the correct interpretation of the Chemical Revolution provides a strong case for the view that progress in science is served by maintaining several incommensurable “systems of practice” in the same discipline, and concerning the same region of nature. This paper is a critical discussion of Chang's reading of the Chemical Revolution. It seeks to establish, first, that (...) Chang's assessment of Lavoisier's and Priestley's work and character follows the phlogistonists' “actors' sociology”; second, that Chang simplifies late-eighteenth-century chemical debates by reducing them to an alleged conflict between two systems of practice; third, that Chang's evidence for a slow transition from phlogistonist theory to oxygen theory is not strong; and fourth, that he is wrong to assume that chemists at the time did not have overwhelming good reasons to favour Lavoisier's over the phlogistonists' views. (shrink)

Compared to its sister disciplines—philosophy of physics and philosophy of biology—philosophy of chemistry remains a relatively young field of philosophical endeavour. Having originated in the late...

The entry of resonance into chemistry, or the reception of the theory of resonance in the chemical community, has drawn considerable attention from historians of science. In particular, they have noted Pauling's ¯amboyant yet effective style of exposition, which became a factor in the early popularity of the resonance theory in comparison to the molecular orbital theory, another way of applying quantum mechanics to chemical problems.$ To be sure, the non-mathematical presentation of the resonance theory by Pauling and (...) his collaborator, George Wheland, helped to facilitate the reception ; but this presentation was vulnerable to the confusion that arose among chemists owing to the similarity between resonance and tautomerism, or between foreign and indigenous concepts. The reception occurred at the expense of serious misunderstandings about resonance. This paper investigates the ways in which Pauling and Wheland taught, and taught about, the theory of resonance, especially their ways of coping with the difficulties of translating a quantum-mechanical concept into chemical language. Their different strategies for teaching resonance theory deserve a thorough examination, not only because the strategies had to do with their solutions of the philosophical question whether resonance is a real phenomenon or not, and whether the theory of resonance is a chemical theory or a mathematical method of approximation, but also because this examination will illuminate the role of chemical translators in the transmission of knowledge across disciplinary boundaries. (shrink)

In this article I examine several related views expressed by Robin Hendry concerning molecular structure, emergence and chemical bonding. There is a long-standing problem in the philosophy of chemistry arising from the fact that molecular structure cannot be strictly derived from quantum mechanics. Two or more compounds which share a molecular formula, but which differ with respect to their structures, have identical Hamiltonian operators within the quantum mechanical formalism. As a consequence, the properties of all such isomers yield precisely (...) the same calculated quantities such as their energies, dipole moments etc. The only means through which the difference between the isomers can be recovered is to build their structures into the quantum mechanical calculations, something that is carried out by the application of the Born-Oppenheimer approximation. Consequently, it has been argued by many authors that molecular structure is written in ‘by hand’ rather than derived. Robin Hendry is one such author, but he goes a great deal further by proposing that this situation implies the existence of emergence and downward causation. In the current article I argue that there are alternative explanations which render emergence and downward causation redundant. Such an alternative lies in the notion of quantum decoherence and the appeal to work in the foundations of physics, which posits that the various isomers exist as a superposition until their wavefunctions are collapsed either by observation or by interacting with their environment. Hendry also alludes to a debate among chemists as to whether chemical bonds are real or not, in the sense of directional connections between two or more nuclei in any given molecule. I reject this view and propose that the structural and energetic views of chemical bonding, that have been discussed by some philosophers of chemistry including Hendry, do not refer to any essential ontological differences. I agree that chemists view bonding in a more realistic fashion and may consider bonds to be in some senses real, while physicists may consider bonding in more abstract energetic terms. However, I do not believe that such differences in scientific practice and attitudes should be considered to offer a window as to the ontological status of bonding or whether bonding is real. Finally, I discuss the kinetic energy school of chemical bonding which would seem to challenge any notion of bonds as directional entities, since bonding is no longer regarded as being primarily due to the build-up of electron density between nuclei. (shrink)

To construct a synthetic cell we need to understand the rules that permit life. A central idea in modern biology is that in addition to the four entities making reality, matter, energy, space and time, a fifth one, information, plays a central role. As a consequence of this central importance of the management of information, the bacterial cell is organised as a Turing machine, where the machine, with its compartments defining an inside and an outside and its metabolism, reads and (...) expresses the genetic program carried by the genome. This highly abstract organisation is implemented using concrete objects and dynamics, and this is at the cost of repeated incompatibilities (frustration), which need to be sorted out by appropriate «patches». After describing the organisation of the genome into the paleome (sustaining and propagating life) and the cenome (permitting life in context), we describe some chemical hurdles that the cell as to cope with, ending with the specific case of the methionine salvage pathway. (shrink)

The exploration of chemical periodicity over the past 250 years led to the development of the Periodic System of Elements and demonstrates the value of vague ideas that ignored early scientific anomalies and instead allowed for extended periods of normal science where new methodologies and concepts are developed. The basic chemical element provides this exploration with direction and explanation and has shown to be a central and historically adaptable concept for a theory of matter far from the reductionist (...) frontier. This is explored in the histories of Prout’s hypothesis, Döbereiner Triads, element inversions necessary when ordering chemical elements by atomic weights, and van den Broeck’s ad-hoc proposal to switch to nuclear charges instead. The development of more accurate methods to determine atomic weights, Rayleigh and Ramsey’s gas separation and analytical techniques, Moseley’s X-ray spectroscopy to identify chemical elements, and more recent accelerator-based cold fusion methods to create new elements at the end of the Periodic Table point to the importance of methodological development complementing conceptual advances. I propose to frame the crossover from physics to chemistry not as a loss of accuracy and precision but as an increased application of vague concepts such as similarity which permit classification. This approach provides epistemic flexibility to adapt to scientific anomalies and the continued growth of chemical compound space and rejects the Procrustean philosophy of reductionist physics. Furthermore, it establishes chemistry with its explanatory and operational autonomy epitomized by the periodic system of elements as a gateway to other experimental sciences. (shrink)

There are two links that stand in the foreground of Deleuze’s treatment of Epicurus and Lucretius: the themes of immanent naturalism and of the externality of ontological relations. However, the links are problematised in Difference and Repetition, which presents an important critique of the concept of the atom. I will argue that this critique reveals the limits of the intellectual affinity between ancient atomism and Deleuzian metaphysics; in particular, that Deleuze’s notions of relationality and spatium respond to problems raised (...) by the relations between atoms and by the not-being of the atomists’ vacuum. In this sense, Deleuze’s treatment of atomism is significant because it makes clear Deleuze’s aim in shifting the mereological vocabulary from points to lines; it shows what, in Deleuze’s sense, it means to unfound and sets down the conditions for a successful Deleuzian critique of essentialist varieties of the metaphysics of structure. (shrink)

Abstract: Lucretius made it plain that his poem was designed to liberate man from superstition, the fear of death and the tyranny of priests: \"When man’s life lay for all to see foully groveling upon the ground, crushed, which displayed her head from the regions of heaven, lowering over mortals with horrible aspect, a man of Greece was the first that dared to uplift mortal eyes against her. . . . but all the more they goaded the eager courage of (...) his soul, so that he should desire, first of all men, to shatter the confining bars of nature’s gates. \". (shrink)

Contingentism, generally contrasted with law necessitarianism, is the view that the laws of nature are contingent. It is often coupled with the claim that their contingency is knowable a priori. This paper considers Bird's (2001, 2002, 2005, 2007) arguments for the thesis that, necessarily, salt dissolves in water; and it defends his view against Beebee's (2001) and Psillos's (2002) contingentist objections. A new contingentist objection is offered and several reasons for scepticism about its success are raised. It is concluded that (...) certain higher-level laws describing the behaviours of molecular compounds may be necessary due to their dependence on underlying physical laws, and that the modal status of laws of nature cannot be determined a priori, as the structural features of the substances and properties they govern must first be investigated. (shrink)