Recent advances in stem cell-derived human brain organoids and microelectrode array (MEA) tech- nology raise profound questions about the potential for these systems to give rise to sentience. Brain organoids are 3D tissue constructs that recapitulate key aspects of brain development and function, while MEAs enable bidirectional communication with neuronal cultures. As brain organoids become more sophisticated and integrated with MEAs, the question arises: Could such a system support not only intelligent computation, but subjective experience? This paper explores the philosophical (...) implications of this thought experiment, considering scenarios in which brain organoids exhibit signs of sensory awareness, distress, preference, and other hallmarks of sentience. It examines the ethical quandaries that would arise if compelling evidence of sentience were found in brain organoids, such as the moral status of these entities and the permissibility of different types of research. The paper also explores how the phenomenon of organoid sentience might shed light on the nature of consciousness and the plausibility of artificial sentience. While acknowledging the speculative nature of these reflections, the paper argues that the possibility of sentient brain organoids deserves serious consideration given the rapid pace of advances in this field. Grappling with these questions proactively could help set important ethical boundaries for future research and highlight critical avenues of scientific and philosophical inquiry. The thought experiment of sentient brain organoids thus serves as a valuable lens for examining deep issues at the intersection of neuroscience, ethics, and the philosophy of mind. (shrink)

Social Justice is a concept familiar to most Indians but one whose meaning is not always understood as it signifies a variety of government strategies designed to enhance opportunities for underprivileged groups. By tracing the trajectory of social justice from the colonial period to the present, this book examines how it informs ideas, practices and debates on discrimination and disadvantage today. After outlining the historical context for reservations for scheduled castes and scheduled tribes that began under British colonial rule, the (...) book examines the legal and moral strands of demands raised by newer groups since 1990. In addition the book shows how the development of quota policies has been significantly influenced by the nature and operation of democracy in India. It describes the recent proliferation of quota demands for reservations in higher education, private sector and for women and religious minorities in legislative assemblies. The book goes on to argue that while proliferation of demands address unequal incidence of poverty, deprivation and inequalities across social groups and communities, care has to be taken to ensure that existing justifications for quotas for discriminated groups due to caste hierarchies are not undermined. Providing a rich historical background to the subject, the book is a useful contribution to the study on the evolution of multiple conceptions of social justice in contemporary India. (shrink)

Environment is the sum total of conditions in which an organism has to maintain its life process in order to survive. It consists of matter and energy. The interaction of matter and energy forms a system of abiotic (non-living) and biotic (living) components. All organisms including humans are parts of biotic components. Society is a group of people who share a common economic, social and industrial infrastructure or an organization of people who share a common cultural and social background having (...) many issues. Human beings live both in natural and social world. Biodiversity simply means the existence of a wide variety of plant and animal species in their natural environments. The current advancement shows strong impacts on the natural as well as social issues and both these influence the biodiversity of a particular region. (shrink)

Ambedkar denounced caste system for violating the respect and dignity of the individual; yet his critique of caste-ridden society also foregrounds the limits of the theory and practice of citizenship and liberal politics in India. Since membership of a caste group was not a voluntary choice, but determined by birth and hence a coercive association, the liberal view of the self as a totally unencumbered and radically free subject seemed plagued with difficulties. Though the nation state envisages a political community (...) co-extensive with one cultural community, it need not, Ambedkar argued, necessarily lead to abolition of discriminatory caste practices in civil society. To restore the cultural rights of stigmatised populations, unredeemed by the nation state, propelled Ambedkar to seek solution in B. (shrink)

Common-sense morality divides acts into those that are right and those that are wrong, but it thinks some wrong acts are more seriously wrong than others, for example murder than breaking a promise. If an act is more seriously wrong, you should feel more guilt about it and, other things equal, are more blameworthy for it and can deserve more punishment; more serious wrongs are also more to be avoided given empirical or moral uncertainty. This paper examines a number of (...) different views about what makes for more serious wrongness and considers the possibility that this may be different for acts that violate deontological vs. consequentialist duties. It also asks whether there’s a parallel concept that admits of degrees on the side of rightness, one of being, as we can say, more importantly right. (shrink)

B R Ambedkar’s reinterpretation of Buddhism gives us an account of action that is based on democratic politics of contest and resistance. It relies on a reading of the self as a multiple creature that exceeds the constructions of liberal autonomy. Insofar as Buddhist groups do not jeopardise or restrict their members’ capacities and opportunities to make any decision about their own lives, they do not risk violating democratic principles. But to remain socially relevant they must continue to contribute to (...) a practical impact on the social world which is so neatly intertwined with the political in present-day India. (shrink)

An embedded ideology of the religious-secular binary in its various forms has assumed currency in recent continental and Anglo-American political thought. This ideology highlights the difference between religion under modernization, broadly defined by the secularization thesis, and that of religious revival in a period characterized by postsecularism. It reflects the rise of new epistemologies and the dissolution of the antinomies between faith and reason characteristic of a postsecular culture. A common argument found in these writings is that enlightenment secularization, which (...) relegates the sacred to a private sphere, seems to have discovered its own parochialism as religion continues to provide…. (shrink)

Recent feminist critiques of development have questioned some fundamental assumptions of feminist political theory; such critiques have also been successful in subverting long-held assumptions of conventional economic development. Viewed in the context of women’s subordination in third world countries, a redefinition of development must not only be about economic growth, but ensure a redistribution of resources, challenge the gender-based division of labour and also seek to provide for an egalitarian basis in social arrangements. Further, as this article argues, any starting (...) point for feminist critiques of development must also seek to link the end of gender oppression to multiple theories of justice – a justice not juridical but one that recognises the cultural membership of women in the community. (shrink)

The debate on equality and non-discrimination is certainly not a new one, but the way it is incorporated in that on social exclusion leads to several shifts within the discourse on social justice. The term social exclusion is multidimensional although its western use in a selective way about markets promoting equality separates it from the Indian emphasis on social justice as linked to ending discrimination of dalit groups. The concept of social exclusion is inherently problematic as it faces three major (...) challenges in India: the first relates to the historical discrimination of certain groups and their exclusion; the second is about the political economy of the excluded; and the third questions the way in which equality responses are restricted within the framework of social exclusion. (shrink)

Philosophers working in the nascent field of ‘experimental philosophy’ have begun using methods borrowed from psychology to collect data about folk intuitions concerning debates ranging from action theory to ethics to epistemology. In this paper we present the results of our attempts to apply this approach to the free will debate, in which philosophers on opposing sides claim that their view best accounts for and accords with folk intuitions. After discussing the motivation for such research, we describe our methodology of (...) surveying people’s prephilosophical judgments about the freedom and responsibility of agents in deterministic scenarios. In two studies, we found that a majority of participants judged that such agents act of their own free will and are morally responsible for their actions. We then discuss the philosophical implications of our results as well as various difficulties inherent in such research. (shrink)

The essays study from different perspectives, the much discussed and crucial topic of social discrimination, and particularly Dalit exploitation. The work is highly interdisciplinary in nature-relevant for several subjects and disciplines such as political science, sociology, Dalit studies, minority studies, women's studies, anthropology, law, economics This work specifically sets out to explore contemporary manifestations of discrimination that persist in our society through institutions and through norms and practices that define the terms on which certain social groups continue to be excluded. (...) The contributors bring in different critical perspectives from their different disciplines. (shrink)

Felix Klein and Abraham Fraenkel each formulated a criterion for a theory of infinitesimals to be successful, in terms of the feasibility of implementation of the Mean Value Theorem. We explore the evolution of the idea over the past century, and the role of Abraham Robinson's framework therein.

This paper deals with the acute toxicity of Sugar factory effluent on freshwater catfish, Mystus vittatus (Bloch), at different concentration and duration of exposure on the mortality and ethological alterations. The LC50 for 96 hours of sugar factory effluent for Mystus vittatus was 3.10% (v/v). The result also revealed that mortality rate depends upon concentrations of effluent and duration of exposure. The effluent exposed test fish showed alterations in behavioural responses. The behavioural alterations of Mystus vittatus during the present experiment (...) was found to depend on both duration of exposure and increase in concentration of the effluent and duration of exposure. The mortality rate was found to be directly proportional to the concentration of effluent. Thus, the present revealed that fish, Mystus vittatus are sensitive to distillery wastewater and can be used as biological indicators. (shrink)

Philosophers often suggest that their theories of free will are supported by our phenomenology. Just as their theories conflict, their descriptions of the phenomenology of free will often conflict as well. We suggest that this should motivate an effort to study the phenomenology of free will in a more systematic way that goes beyond merely the introspective reports of the philosophers themselves. After presenting three disputes about the phenomenology of free will, we survey the (limited) psychological research on the experiences (...) relevant to the philosophical debates and then describe some pilot studies of our own with the aim of encouraging further research. The data seem to support compatibilist descriptions of the phenomenology more than libertarian descriptions. We conclude that the burden is on libertarians to find empirical support for their more demanding metaphysical theories with their more controversial phenomenological claims. (shrink)

The Indian sarus crane Grus antigone antigone is the world's graceful and tallest flying bird. It is a nonmigratory and only resident breeding crane of Indian sub continent. It has been declared as 'State Bird' by Government of Uttar Pradesh. Pairing of the bird for life long and legendry marital devotion of the species has earned its global popularity. Ecological and environmental condition of this lake is quite supportive for the survival of this vulnerable species. The present study deals with (...) the distribution and conservation of this vulnerable species in and around the Alwara lake of district Kaushambi, Uttar Pradesh. A total of 335 cranes were actually observed in 2012, 425 in 2013, 510 in 2014 and 537 in 2015, although more cranes were claimed to exist in this area by the local people. This communication is clearly depicting continuous increasing trend in population of Indian sarus crane during their exploration from 2012-2015 in the area studied, although its population is decreasing at global level. (shrink)

Drugs used to provide improvement of cognitive functioning have been shown to be effective in healthy individuals. It is sometimes assumed that the use of these drugs constitutes cheating in an academic context. We examine whether this assumption is ethically sound. Beyond providing the most up-to-date discussion of modafinil use in an academic context, this contribution includes an overview of the safety of modafinil use in greater depth than previous studies addressing the issue of cheating. Secondly, we emphasize two crucial, (...) but hitherto nearly overlooked, nuances to the issues: the potential for modafinil to decrease inequality and disadvantage in academic settings, and the fact that how modafinil is used dramatically impacts its effects on health, coercion, fairness, authenticity and effort. Finally, we explicitly defend the position that there are no qualitatively morally relevant differences between modafinil use and other enhancement modalities; any such differences are in degree,... (shrink)

Abstract: The emergence of women entrepreneurs and their contribution to the national economy is quite visible in India. Women’s entrepreneurship has been recognized during the last decade as an important untapped source of economic growth. According to of statistics women in India 2010, proportion of female main workers to total population in percentage is 16.65 in rural areas and 9.42 in urban areas this shows overall less contribution of women in work but more percentage of women workers in rural areas. (...) According to the quick result of the Fourth All India Census of MSMEs (2006-07), there are 26 million MSMEs in India which provides employment to about 60 million people. The sector contributes about 40 % GDP, beside 45% to the total manufacturing output and 40 % to the exports from the country. There could be many opportunities identification hidden inside the challenges for small business concerns. This paper examines various opportunities and challenges for Women Entrepreneurship Development in Micro Small and Medium Enterprise. More precisely the paper explores, rewards for starting a small business, myths about small businesses, new opportunities, four forms of entrepreneurship, identification practices among first generation and major challenges in small business. (shrink)

Summary: Edward Lanphier and colleagues contend that human germline editing is an unethical technology because it could have unpredictable effects on future generations. In our view, such misgivings do not justify their proposed moratorium.

Existing ethical guidelines that aim to guide the development of mental health apps tend to overemphasize the role of Western conceptual frameworks. While such frameworks have proved to be a useful first step in introducing ethics to a previously unregulated industry, the rapid global uptake of mental health apps requires thinking more deeply about the diverse populations these apps seek to serve. One way to do this is to introduce more intercultural ethical perspectives into app design and the guidelines that (...) aim to encourage best practices. In addition to this, existing ethical guidelines can also benefit from the ethical scholarship from the feminist and disability traditions, both of which highlight specific ethical considerations for vulnerable users. Rethinking the ethical responsibilities of mental health app designers through the prisms of feminism, disability studies, and intercultural philosophy leads us to a more global and inclusive set of ethical considerations in app design. This white paper explores what existing guidelines for the regulation of mental health apps are missing. It also explores how these guidelines could be improved for users who inhabit an increasingly diverse and globalized world. (shrink)

While several tests and strategies are recommended for colorectal cancer (CRC) screening, studies suggest that primary care providers often recommend colonoscopy without providing information about its risks or alternatives. These observations raise concerns about the quality of informed consent for screening colonoscopy.

This paper summarizes (in German) recent tendencies in the philosophy of the life sciences.

The United States Fish and Wildlife Service in Alaska, USA, conducted a species status assessment for a petition to list the Alexander Archipelago wolf (Canis lupus ligoni) under the Endangered Species Act in 2020-2022. This federal undertaking could not be adequately prepared without including the knowledge of Indigenous People who have a deep cultural connection with the subspecies. Our objective is to communicate the authoritative expertise and voice of the Indigenous People who partnered on the project by demonstrating how their (...) knowledge contributed to the species status assessment. The Indigenous knowledge applied in the assessment is the cultural and intellectual property of those who have shared it. We employed rapid appraisal research to expeditiously develop a preliminary and qualitative understanding of Indigenous People's cultural and ecological knowledge of Alexander Archipelago wolves. We used semi-directed interviewing and inductive coding from grounded theory for text analysis. Indigenous knowledge contributed to the agency's understanding of the Alexander Archipelago wolf in Southeast Alaska and helped the agency with their classification decision. Indigenous research partners explained the rich cultural significance and position of wolves in Tlingit society and described human–wolf relationships and ecological interactions. The agency used a single-species assessment approach based in species ecology and conservation biology, whereas the Indigenous wolf experts applied a multi-species, community ecology approach based in a sociocultural context of balance and respect. The Indigenous wolf experts successfully addressed knowledge gaps identified by the agency. The partners were challenged by a short regulatory timeframe that did not allow for comprehensive study of Indigenous knowledge and constrained review and feedback by Indigenous experts. The United States Fish and Wildlife Service learned that its assessment framework was not designed to account for an Indigenous worldview. To level the playing field, the agency and Indigenous experts should discuss how to co-develop an assessment framework that equitably applies both perspectives. (shrink)

Methadone maintenance therapy is a cost-effective, evidence-based treatment for heroin dependence. In the USA, a majority of heroin-dependent offenders are forced to detox from methadone when incarcerated. Recent research published in The Lancet has demonstrated the negative health and economic outcomes associated with such policies. Methadone Continuation Versus Forced Withdrawal on Incarceration in a Combined US Prison and Jail: A Randomised, Open Label Trial. The Lancet, 386, 350–359). This novel evidence raises questions as to the justification for current policies of (...) forced detox in American prisons. Opponents of methadone provision in prisons might offer arguments from retributivism, resource allocation and curative effectiveness to justify their position. This article contends that these arguments do not stand up to ethical scrutiny. In light of this, we hold that American policymakers should reform criminal justice policies to allow the initiation and continuation of methadone treatment in correctional settings. This would be consistent with both international recommendations and the example set by a number of other Western countries. (shrink)

Existing studies of the multi-group dynamics of prejudiced societies focus on the social- psychological knowledge behind the relevant processes. We instead create a multi-agent framework that simulates the propagation of prejudice and measures its tangible impact on prosperity. Levels of prosperity are tracked for individuals as well as larger social structures including groups and factions. We model social interactions using the Continuous Prisoner's Dilemma (CPD) and a new agent type called a prejudiced agent. Our simulations show that even modeling prejudice (...) as an exclusively out-group phenomenon nonetheless generates implicit in-group promotion, leading to higher relative prosperity of a prejudiced population. This skew in prosperity is seen to be correlated to factors such as size difference between groups, and the fraction of prejudiced agents in a group. Our model is a step towards a deeper understanding of the origins, propagation, and ramifications of prejudice through simulative studies grounded in apt theoretical backgrounds. (shrink)

The work of Thomas White represents a systematic attempt to combine the best of the new science of the seventeenth century with the best of Aristotelian tradition. This attempt earned him the criticism of Hobbes and the praise of Leibniz, but today, most of his attempts to navigate between traditions remain to be explored in detail. This paper does so for his ontology of accidents. It argues that his criticism of accidents in the category of location as entities over (...) and above substances was likely aimed at Francisco Suárez, and shows how White’s worries about the analysis of location were linked with his broader cosmological views. White rejects real qualities, but holds that the quantity of a substance is somehow distinct from its bearer. This reveals a common ground with some of his scholastic interlocutors, but lays bare a deep disagreement with thinkers like Descartes on the nature of matter. (shrink)

The present investigation was undertaken to investigate the acute toxicity of cadmium, a heavy metal widely detected in the aquatic environment due to natural effects and anthropogenic activities, in freshwater teleost, Channa punctata (Bloch). The experiments for the bioassay were performed in semi-static test condition according to the standard guidelines. The behavioural changes in the fish were observed for all tested concentrations of the metal. The data obtained for bioassay were analyzed for median lethal concentrations (LC ) of the metal (...) by SPSS computer software. The LC 50 50 values, estimated by SPSS, with 95% confidence level were found to be:20.589 (18.326-23.221), 17.133 (14.840- 19.734), 11.815 (9.696 – 13.850) mg/L and 9.908 (7.635-12381) mg/L for cadmium chloride at 24, 48, 72 and 96 h exposure, respectively. (shrink)

The translational research community, in general, and the Clinical and Translational Science Awards (CTSA) community, in particular, share the vision of repurposing EHRs for research that will improve the quality of clinical practice. Many members of these communities are also aware that electronic health records (EHRs) suffer limitations of data becoming poorly structured, biased, and unusable out of original context. This creates obstacles to the continuity of care, utility, quality improvement, and translational research. Analogous limitations to sharing objective data in (...) other areas of the natural sciences have been successfully overcome by developing and using common ontologies. This White Paper presents the authors’ rationale for the use of ontologies with computable semantics for the improvement of clinical data quality and EHR usability formulated for researchers with a stake in clinical and translational science and who are advocates for the use of information technology in medicine but at the same time are concerned by current major shortfalls. This White Paper outlines pitfalls, opportunities, and solutions and recommends increased investment in research and development of ontologies with computable semantics for a new generation of EHRs. (shrink)

Human agents happen to judge that a conjunction of two terms is more probable than one of the terms, in contradiction with the rules of classical probabilities—this is the conjunction fallacy. One of the most discussed accounts of this fallacy is currently the quantum-like explanation, which relies on models exploiting the mathematics of quantum mechanics. The aim of this paper is to investigate the empirical adequacy of major quantum-like models which represent beliefs with quantum states. We first argue that they (...) can be tested in three different ways, in a question order effect configuration which is different from the traditional conjunction fallacy experiment. We then carry out our proposed experiment, with varied methodologies from experimental economics. The experimental results we get are at odds with the predictions of the quantum-like models. This strongly suggests that this quantum-like account of the conjunction fallacy fails. Future possible research paths are discussed. (shrink)

This is the introductory essay to the collection of essays: 'Acquaintance: New Essays' (eds. Knowles & Raleigh, forthcoming, OUP). In this essay I provide some historical background to the concept of acquaintance. I examine various Russellian theses about acquaintance that contemporary acquaintance theorists may wish to reject. I consider a number of questions that acquaintance theorists face. I provide a survey of current debates in philosophy where acquaintance has recently been invoked. And I also provide brief summaries of the other (...) essays in this volume. (shrink)

: New genetic technologies continue to emerge that allow us to control the genetic endowment of future children. Increasingly the claim is made that it is morally "irresponsible" for parents to fail to use such technologies when they know their possible children are at risk for a serious genetic disorder. We believe such charges are often unwarranted. Our goal in this article is to offer a careful conceptual analysis of the language of irresponsibility in an effort to encourage more care (...) in its use. Two of our more important sub-claims are: A fair judgment of genetic irresponsibility necessarily requires a thick background description of the specific reproductive choice; and there is no necessary connection between an act's being morally wrong and its being irresponsible. These are distinct judgments requiring distinct justifications. (shrink)

Ever since its inception, the theory of evolution has been reified into an “-ism”: Darwinism. While biologists today tend to shy away from the term in their research, the term is still actively used in the broader academic and societal contexts. What exactly is Darwinism, and how precisely are its various uses and abuses related to the scientific theory of evolution? Some call for limiting the meaning of the term “Darwinism” to its scientific context; others call for its abolition; yet (...) others claim the term refers to a myth-like story. In this paper we propose a conceptually grounded overview of the term. We show how the scientific dimension of Darwinism feeds into, and is influenced by, guises of Darwinism as a methodology and as an ethically and politically charged “worldview”. The full meaning of Darwinism, as well as how this meaning has changed over time, can only be understood through the complex interaction between these three dimensions. (shrink)

A good account of the agnostic attitude of Suspending Judgement should explain how it can be rendered more or less rational/justified according to the state of one's evidence – and one's relation to that evidence. I argue that the attitude of suspending judgement whether p constitutively involves having a belief; roughly, a belief that one cannot yet tell whether or not p. I show that a theory of suspending that treats it as a sui generis attitude, wholly distinct from belief, (...) struggles to account for how suspension of judgement can be rendered more or less rational (or irrational) by one's evidence. I also criticise the related idea that suspension essentially requires an 'Inquiring Attitude'. I show how a belief-based theory, in contrast, neatly accounts for the rational and epistemic features of suspending and so neatly accounts for why an agnostic has a genuine neutral opinion concerning the question whether p, as opposed to simply having no opinion. (shrink)

According to the so-called Classical Theory, concepts are mentally represented by individually necessary and jointly sufficient application conditions. One of the principal empirical objections against this view stems from evidence that people judge some instances of a concept to be more typical than others. In this paper we present and discuss four empirical studies that investigate the extent to which this ‘typicality effect’ holds for the concept of basic needs. Through multiple operationalizations of typicality, our studies yielded evidence for a (...) strong effect of this kind: Participants tended to recall the same core examples of the concept in a free-listing task. They judged some basic needs to be more typical than others. The items that were judged to be more typical were listed more frequently in the free-listing task. These items were listed earlier on in the free-listing task. Typical basic needs, as well as non needs, were classified faster than atypical basic needs in a reaction time study. These findings suggest that the concept of basic needs may have a non-classical structure. If so, the quest for a simple and robust intensional analysis of the concept may be futile. (shrink)

This article argues that Lara Buchak’s risk-weighted expected utility (REU) theory fails to offer a true alternative to expected utility theory. Under commonly held assumptions about dynamic choice and the framing of decision problems, rational agents are guided by their attitudes to temporally extended courses of action. If so, REU theory makes approximately the same recommendations as expected utility theory. Being more permissive about dynamic choice or framing, however, undermines the theory’s claim to capturing a steady choice disposition in the (...) face of risk. I argue that this poses a challenge to alternatives to expected utility theory more generally. (shrink)

According to the recent Perceptual Confidence view, perceptual experiences possess not only a representational content, but also a degree of confidence in that content. The motivations for this view are partly phenomenological and partly epistemic. We discuss both the phenomenological and epistemic motivations for the view, and the resulting account of the interface between perceptual experiences and degrees of belief. We conclude that, in their present state of development, orthodox accounts of perceptual experience are still to be favoured over the (...) perceptual confidence view. (shrink)

Is it possible for an individual that has gone out of being to come back into being again? The English Aristotelian, Thomas White, argued that it is not. Thomas Hobbes disagreed, and used the case of the Ship of Theseus to argue that individuals that have gone out of being may come back into being again. This paper provides the first systematic account of their arguments. It is doubtful that Hobbes has a consistent case against White. Still his (...) criticism may have prompted White to clarify his views on identity over time in his later work. (shrink)

The claim that common sense regards free will and moral responsibility as compatible with determinism has played a central role in both analytic and experimental philosophy. In this paper, we show that evidence in favor of this “natural compatibilism” is undermined by the role that indeterministic metaphysical views play in how people construe deterministic scenarios. To demonstrate this, we re-examine two classic studies that have been used to support natural compatibilism. We find that although people give apparently compatibilist responses, this (...) is largely explained by the fact that people import an indeterministic metaphysics into deterministic scenarios when making judgments about freedom and responsibility. We conclude that judgments based on these scenarios are not reliable evidence for natural compatibilism. (shrink)

Andreas Schmidt and Neil Levy have recently defended nudging against the objection that nudges fail to treat nudgees as rational agents. Schmidt rejects two theses that have been taken to support the objection: that nudges harness irrational processes in the nudgee, and that they subvert the nudgee’s rationality. Levy rejects a third thesis that may support the objection: that nudges fail to give reasons. I argue that these defences can be extrapolated from nudges to some nonconsensual neurointerventions; if Schmidt’s and (...) Levy’s defences succeed, then some nonconsensual neurointerventions neither harness irrationality, nor subvert rationality, nor fail to give reasons. This, I claim, poses a challenge both to opponents of nonconsensual neurointerventions, and to defenders of nudging. (shrink)

Mathematicians, physicists, and philosophers of physics often look to the symmetries of an object for insight into the structure and constitution of the object. My aim in this paper is to explain why this practice is successful. In order to do so, I present a collection of results that are closely related to (and in a sense, generalizations of) Beth’s and Svenonius’ theorems.

In my fourth year, I completed a research paper critically analyzing writing on Endurance and Perdurance by testing these theories of how objects persist through change with Einstein’s Relativity to present a thesis. I then compared these metaphysical accounts of persistence for how well they conform to applied physical principles of Special Relativity.

Intuitions play an important role in the debate on the causal status of high‐level properties. For instance, Kim has claimed that his “exclusion argument” relies on “a perfectly intuitive … understanding of the causal relation.” We report the results of three experiments examining whether laypeople really have the relevant intuitions. We find little support for Kim's view and the principles on which it relies. Instead, we find that laypeople are willing to count both a multiply realized property and its realizers (...) as causes, and regard the systematic overdetermination implied by this view as unproblematic. (shrink)

Theories of explanation need to account for a puzzling feature of our explanatory practices: the fact that we prefer explanations that are relatively abstract but only moderately so. Contra Franklin-Hall ([2016]), I argue that the interventionist account of explanation provides a natural and elegant explanation of this fact. By striking the right balance between specificity and generality, moderately abstract explanations optimally subserve what interventionists regard as the goal of explanation, namely identifying possible interventions that would have changed the explanandum.

Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance localized within a microenvironment. This review shows that the protection against pathogens also involves the mitigation of pathogenic impact without eliminating the pathogens (i.e., “disease tolerance”) and the containment of microorganisms to prevent pathogenic spread. Protective microorganisms can have an impact beyond their niche, interfering with (...) the entry, establishment, growth, and spread of pathogenic microorganisms. More fundamentally, we propose a series of conceptual clarifications in support of the idea of a “co-immunity,” where an organism is protected by both its own immune system and components of its microbiota. -/- . (shrink)

The main thesis of this paper is that Pap’s The Functional A Priori of Physical Theory (Pap 1946, henceforth FAP) and Cassirer’s Determinism and Indeterminism in Modern Physics (Cassirer 1937, henceforth DI) may be conceived as two kindred accounts of a late Neo-Kantian philosophy of science. They elucidate and clarify each other mutually by elaborating conceptual possibilities and pointing out affinities of neo-Kantian ideas with other currents of 20th century’s philosophy of science, namely, pragmatism, conventionalism, and logical empiricism. Taking into (...) account these facts, it seems not too far fetched to conjecture that under more favorable circumstances Pap could have served as a mediator between the “analytic” and “continental” tradition thereby overcoming the dogmatic dualism of these two philosophical currents that has characterized philosophy in the second half the 20th century. (shrink)

We can cause windows to break and we can break windows; we can cause villages to flood and we can flood villages; and we can cause chocolate to melt and we can melt chocolate. Each time these can come apart: if, for example, A merely instructs B to break the window, then A causes the window to break without breaking it herself. Each instance of A breaking/flooding/melting/burning/killing/etc. something, is an instance of what I call making. I argue that making is (...) an independent, theoretically important notion—akin but irreducible to causing—and metaphysicians should pay attention to it. (shrink)

This paper accomplishes three goals. First, the essay demonstrates that Edmund Husserl’s theory of meaning consciousness from his 1901 Logical Investigations is internally inconsistent and falls apart upon closer inspection. I show that Husserl, in 1901, describes non-intuitive meaning consciousness as a direct parallel or as a ‘mirror’ of intuitive consciousness. He claims that non-intuitive meaning acts, like intuitions, have substance and represent their objects. I reveal that, by defining meaning acts in this way, Husserl cannot account for our experiences (...) of countersensical, absurd, or impossible meanings. Second, I examine how Husserl came to recognize this 1901 mistake in his 1913/14 Revisions to the Sixth Logical Investigation. I discuss how he accordingly reformulates his understanding of non-intuitive meaning acts from the ground up in those Revisions, where this also allows for him to properly account for the experience of impossible meanings. Instead of describing them as mirrors of intuitions, Husserl takes non-intuitive meaning acts to be modifications of intuitions, where they have no substance and do not represent their objects. Finally, in the conclusion to this essay, I demonstrate how this fundamental change to his understanding of meaning consciousness forced Husserl to revise other central tenets of his philosophy, such that the trajectory of his thought can only be properly understood in light of these revisions to his theory of non-intuitive meaning consciousness. (shrink)