Results for 'metabolic biochemistry'

83 found
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  1. La estructura de la bioquímica metabólica.Ana Donolo, Lucía Federico & Pablo Lorenzano - 2016 - Metatheoria – Revista de Filosofía E Historia de la Ciencia 7:49--72.
    The structuralist reconstruction of the metabolic biochemistry here presented is a more complete and revised version than the one presented in Donolo, Federico & Lorenzano (2006). This version, as the previous one, continues with the reconstructive task initiated by César Lorenzano (2002), but advances further on those elements which remained pendent of reconstruction: applications subsequent to the paradigmatic one, for being these “too diversified and numerous” (p. 210).In line with which is said before, the objective of this new (...)
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  2. Basant (Spring) - The Splendour of Nature.Devinder Pal Singh - 2021 - The Sikh Review 69 (3):11-19.
    Basant (Spring) is a time of dawning light, new life, new birth, and new hope — a time of warmth, vitality, dancing, and blossoming. Every year she comes out of the cold darkness and captivatingly dances around us. She embraces us with her warmth, intoxicates us with her aroma. Like a potent elixir, spring revitalizes our hope. She breathes life into the dead and teaches us the lessons of renewal and rebirth [1]. The dawn of Basant has well appreciated in (...)
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  3. What Is Life: An Informational Model of the Living Structures.Florin Gaiseanu - 2020 - Biochemistry and Molecular Biology 5 (2):18-28.
    Schröedinger’s question “what is life?” was a real challenge for the scientific community and this still remains as an opened question, because in spite of the important advances in various scientific branches like philosophy, biology, chemistry and physics,, each of them assesses life from its particular point of view to explain the life’ characteristic features, so not a coherent and well structured general model of life was reported. In this paper life is approached from informational perspective, starting from earlier Draganeacu's (...)
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  4. Metabolic theories of Whipple disease.Oscar Morice, Mathew Elameer, Mina Arsanious, Helen Stephens, Eleanor Soutter, Thomas Hughes & Brendan Clarke - manuscript
    Whipple disease is a rare, infectious, disease first described from a single case by Whipple in 1907. As well as characterising the clinical and pathological features of the condition, Whipple made two suggestions regarding its aetiology. These were either than the disease was caused by an infectious agent, or that it was of metabolic origin. As the disease is now thought to be caused by infection with the bacterium Tropheryma whipplei, historical reviews of the history of the disease typically (...)
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  5. Vascular-metabolic and GABAergic Inhibitory Correlates of Neural Variability Modulation. A Combined fMRI and PET Study.Timothy J. Lane - 2018 - Neuroscience 379:142-151.
    Neural activity varies continually from moment to moment. Such temporal variability (TV) has been highlighted as a functionally specific brain property playing a fundamental role in cognition. We sought to investigate the mechanisms involved in TV changes between two basic behavioral states, namely having the eyes open (EO) or eyes closed (EC) in vivo in humans. To these ends we acquired BOLD fMRI, ASL, and [18F]-fluoro-deoxyglucose PET in a group of healthy participants (n = 15), along with BOLD fMRI and (...)
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  6. Determination of Reference Intervals of Biochemistry Parameters in healthy individuals in Gaziantep Province.Mustafa Örkmez & Mehmet Tarakçıoğlu - 2023 - European Journal of Therapeutics 29 (2):173-178.
    Objective: Reference values have gained universal acceptance as the most powerful material that helps the decision-making-implementation process of the clinical laboratory. These values ​​may be affected by the geographical location, dietary habits, and other lifestyle changes of individuals applying to the clinical laboratory. Our study aims to determine the reference ranges for the biochemistry test panel, thyroid function tests, and insulin hormone levels, which are frequently needed by clinicians for the province of Gaziantep, with samples obtained from healthy individuals. (...)
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  7. Effects of Moderate Exercise Training On ApoE And ApoCIII In Metabolic Syndrome.Kutluhan Ertekin, Metin Baştuğ & Asena Gökçay Canpolat - 2023 - European Journal of Therapeutics 29 (1):65-73.
    Introduction: Metabolic syndrome (MetS) is an endocrinopathy with a combination of cardiovascular and metabolic compounds. In our study, it is expected to obtain results showing that mortality rate, loss of workforce, and treatment costs due to disorders caused by MetS can be reduced by physical exercise. The study analyses the effect of moderate exercise training on this Apolipoprotein E (ApoE), Apolipoprotein CIII (ApoCIII), adiponectin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) which are thought to have a role (...)
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  8. Reengineering Metaphysics: Modularity, Parthood, and Evolvability in Metabolic Engineering.Catherine Kendig & Todd T. Eckdahl - 2017 - Philosophy, Theory, and Practice in Biology 9 (8).
    The premise of biological modularity is an ontological claim that appears to come out of practice. We understand that the biological world is modular because we can manipulate different parts of organisms in ways that would only work if there were discrete parts that were interchangeable. This is the foundation of the BioBrick assembly method widely used in synthetic biology. It is one of a number of methods that allows practitioners to construct and reconstruct biological pathways and devices using DNA (...)
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  9. Changes in serum biochemistry of fish, Channa punctatus in response to nickel toxicity.Mukul Sinha - 2021 - IJAR 7 (8):459-461.
    The present investigation has been designed to study the effect of sub lethal concentrations of Nickel on the serum metabolites of Channa punctatus after exposure to 45 days. The present study shows that serum metabolites such as glucose and protein were significantly decreased while lipid was significantly increased. Thus, the result provides an overview of the manipulation of fish, Channa punctatus as a biomarker of heavy metals through alternation in serum biochemical parameters.
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  10. The Role of Vitamin D in the Incidence of Metabolic Syndrome in Undergraduate Female Students in Saudi Arabia.aHala M. Abdelkarem, Aishah H. Alamri, bFadia Y. Abdel Megeid, cMervat M. Al-Sayed & Omyma K. Radwan - 2018 - International Journal of Academic Health and Medical Research (IJAHMR) 2 (11):7-12.
    Abstract: Background: Vitamin D insufficiency/deficiency prevalent in all age groups across the world is common in obesity and may play an important role in the risk factors of metabolic syndrome (MS). Objectives: This cross-sectional study is to evaluate the relationship between levels of adiponectin and circulating 25(OH)D, and its effect on metabolic biomarker among overweight/obese female students. Methods: Three hundred female students; with mean age 20.9 ± 3.2 years were attending the Aljouf University, Sakaka, Saudi Arabia. They were (...)
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  11. Correction to: Determination of Reference Intervals of Biochemistry Parameters in healthy individuals in Gaziantep Province.Mustafa Örkmez & Mehmet Tarakçıoğlu - 2024 - European Journal of Therapeutics 30 (2):248-248.
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  12. L’assenza di sinonimia tra metabolé, kínesis e génsis nella dottrina Aristotelica del divenire.Giampaolo Abbate - 2016 - Anais de Filosofia Clássica 10 (20):85-109.
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  13. The Human Aspect of Christ between Classic and Quantum Consciousness: Gethsemane - Anxiety & Depression between Biochemistry & Anthropology.Massimo Cocchi, Lucio Tonello & Fabio Gabrielli - 2012 - Scientific GOD Journal:432-439.
    The studies carried out in recent years on the molecular dynamics of consciousness, especially in relation to diseases such as major depression and bipolar disorder, on man considered as a synthesis of nature and culture, in their interdisciplinary and transdisciplinary expression, prompted us to carry out the molecular logic involving the human component of Christ (Christ-Man). On the basis of evidence presented in the Holy Scriptures, regarding the hours that preceded his death, we tend, in the light of the molecular (...)
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  14. Field equations, quantum mechanics and geotropism.Han J. F. Geurdes - manuscript
    The biochemistry of geotropism in plants and gravisensing in e.g. cyanobacteria or paramacia is still not well understood today [1]. Perhaps there are more ways than one for organisms to sense gravity. The two best known relatively old explanations for gravity sensing are sensing through the redistribution of cellular starch statoliths and sensing through redistribution of auxin. The starch containing statoliths in a gravity field produce pressure on the endoplasmic reticulum of the cell. This enables the cell to sense (...)
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  15. Information-Matter Bipolarity of the Human Organism and Its Fundamental Circuits: From Philosophy to Physics/Neurosciences-Based Modeling.Florin Gaiseanu - 2020 - Philosophy Study 10 (2):107-118.
    Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of the human organism, distinguishing three fundamental circuits for its survival, which demonstrates and supports this statement, as a base for further development of the informational model of consciousness to a general informational model of the human organism. For this, it was examined the Informational System of the Human (...)
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  16. Is Captain Kirk a natural blonde? Do X-ray crystallographers dream of electron clouds? Comparing model-based inferences in science with fiction.Ann-Sophie Barwich - 2017 - In Otávio Bueno, Steven French, George Darby & Dean Rickles (eds.), Thinking About Science, Reflecting on Art: Bringing Aesthetics and Philosophy of Science Together. New York: Routledge.
    Scientific models share one central characteristic with fiction: their relation to the physical world is ambiguous. It is often unclear whether an element in a model represents something in the world or presents an artifact of model building. Fiction, too, can resemble our world to varying degrees. However, we assign a different epistemic function to scientific representations. As artifacts of human activity, how are scientific representations allowing us to make inferences about real phenomena? In reply to this concern, philosophers of (...)
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  17. Biochemical Kinds.Jordan Bartol - 2014 - British Journal for the Philosophy of Science (2):axu046.
    Chemical kinds (e.g. gold) are generally treated as having timelessly fixed identities. Biological kinds (e.g. goldfinches) are generally treated as evolved and/or evolving entities. So what kind of kind is a biochemical kind? This paper defends the thesis that biochemical molecules are clustered chemical kinds, some of which–namely, evolutionarily conserved units–are also biological kinds.On this thesis, a number of difficulties that have recently occupied philosophers concerned with proteins and kinds are shown to be resolved or dissolved.
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  18.  54
    Teacher needs manifold skills in the Modern Educational Process.Dhastagir S. Sheriff - 2024 - Mediterranean Journal of Pharmacy and Pharmaceutical Sciences 4 (4):6-8.
    My journey as a teacher started in 1971, keeping the student's interests in mind. The experiences gained through observing some of the best teachers in mind like Dr. Gopalan (Director General of ICMR) Dr. Srikantia (Director, National Institute of Nutrition, Hyderabad), and Dr. Copper (Madras Medical College) I developed an interest in teaching. What I learned was to teach in a simple language that is relevant to the field of education. Being a Rotarian as well as having the opportunity of (...)
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  19. A Manifesto for a Processual Philosophy of Biology.John A. Dupre & Daniel J. Nicholson - 2018 - In Daniel J. Nicholson & John Dupré (eds.), Everything Flows: Towards a Processual Philosophy of Biology. Oxford, United Kingdom: Oxford University Press.
    This chapter argues that scientific and philosophical progress in our understanding of the living world requires that we abandon a metaphysics of things in favour of one centred on processes. We identify three main empirical motivations for adopting a process ontology in biology: metabolic turnover, life cycles, and ecological interdependence. We show how taking a processual stance in the philosophy of biology enables us to ground existing critiques of essentialism, reductionism, and mechanicism, all of which have traditionally been associated (...)
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  20. Developmental Programming, Evolution, and Animal Welfare: A Case for Evolutionary Veterinary Science.Walter Veit & Heather Browning - 2021 - Journal of Applied Animal Welfare Science 1.
    The conditions animals experience during the early developmental stages of their lives can have critical ongoing effects on their future health, welfare, and proper development. In this paper we draw on evolutionary theory to improve our understanding of the processes of developmental programming, particularly Predictive Adaptive Responses (PAR) that serve to match offspring phenotype with predicted future environmental conditions. When these predictions fail, a mismatch occurs between offspring phenotype and the environment, which can have long-lasting health and welfare effects. Examples (...)
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  21. Metabolism Instead of Machine: Towards an Ontology of Hybrids.Julia Rijssenbeek, Vincent Blok & Zoë Robaey - 2022 - Philosophy and Technology 35 (3):1-23.
    The emerging field of synthetic biology aims to engineer novel biological entities. The envisioned future bio-based economy builds largely on “cell factories”: organisms that have been metabolically engineered to sustainably produce substances for human ends. In this paper, we argue that synthetic biology’s goal of creating efficient production vessels for industrial applications implies a set of ontological assumptions according to which living organisms are machines. Traditionally, a machine is understood as a technological, isolated and controllable production unit consisting of parts. (...)
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  22. Robust processes and teleological language.Jonathan Birch - 2012 - European Journal for Philosophy of Science 2 (3):299-312.
    I consider some hitherto unexplored examples of teleological language in the sciences. In explicating these examples, I aim to show (a) that such language is not the sole preserve of the biological sciences, and (b) that not all such talk is reducible to the ascription of functions. In chemistry and biochemistry, scientists explaining molecular rearrangements and protein folding talk informally of molecules rearranging “in order to” maximize stability. Evolutionary biologists, meanwhile, often speak of traits evolving “in order to” optimize (...)
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  23. Biochemical functions.Francesca Bellazzi - forthcoming - British Journal for the Philosophy of Science.
    Function talk is a constant across different life sciences. From macro-evolution to genetics, functions are mentioned everywhere. For example, a limb’s function is to allow movement and RNA polymerases’ function is to transcribe DNA. Biochemistry is not immune from such a characterization; the biochemical world seems to be a chemical world embedded within biological processes. Specifically, biochemists commonly ascribe functions to biomolecules and classify them accordingly. This has been noticed in the recent philosophical literature on biochemical kinds. But while (...)
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  24.  98
    Interpretable and accurate prediction models for metagenomics data.Edi Prifti, Antoine Danchin, Jean-Daniel Zucker & Eugeni Belda - 2020 - Gigascience 9 (3):giaa010.
    Background: Microbiome biomarker discovery for patient diagnosis, prognosis, and risk evaluation is attracting broad interest. Selected groups of microbial features provide signatures that characterize host disease states such as cancer or cardio-metabolic diseases. Yet, the current predictive models stemming from machine learning still behave as black boxes and seldom generalize well. Their interpretation is challenging for physicians and biologists, which makes them difficult to trust and use routinely in the physician-patient decision-making process. Novel methods that provide interpretability and biological (...)
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  25. RNA’s Role in the Origins of Life: An Agentic ‘Manager’, or Recipient of ‘Off-loaded’ Constraints?John E. Stewart - 2021 - Biosemiotics 14 (3):643-650.
    In his Target Article, Terrence Deacon develops simple models that assist in understanding the role of RNA in the origins of life. However, his models fail to adequately represent an important evolutionary dynamic. Central to this dynamic is the selection that impinges on RNA molecules in the context of their association with proto-metabolisms. This selection shapes the role of RNA in the emergence of life. When this evolutionary dynamic is appropriately taken into account, it predicts a role for RNA that (...)
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  26. (1 other version)Adaptivity: From metabolism to behavior.Xabier Barandiaran & Alvaro Moreno - 2008 - Adaptive Behavior 16 (5):325-344.
    In this article, we propose some fundamental requirements for the appearance of adaptivity. We argue that a basic metabolic organization, taken in its minimal sense, may provide the conceptual framework for naturalizing the origin of teleology and normative functionality as it appears in living systems. However, adaptivity also requires the emergence of a regulatory subsystem, which implies a certain form of dynamic decoupling within a globally integrated, autonomous system. Thus, we analyze several forms of minimal adaptivity, including the special (...)
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  27. Norm-Establishing and Norm-Following in Autonomous Agency.Xabier Barandiaran & Matthew Egbert - 2013 - Artificial Life 91 (2):1-24.
    Living agency is subject to a normative dimension (good-bad, adaptive-maladaptive) that is absent from other types of interaction. We review current and historical attempts to naturalize normativity from an organism-centered perspective, identifying two central problems and their solution: (1) How to define the topology of the viability space so as to include a sense of gradation that permits reversible failure, and (2) how to relate both the processes that establish norms and those that result in norm-following behavior. We present a (...)
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  28. An organisational approach to biological communication.Ramiro Frick, Leonardo Bich & Alvaro Moreno - 2019 - Acta Biotheoretica (2):103-128.
    This paper aims to provide a philosophical and theoretical account of biological communication grounded in the notion of organisation. The organisational approach characterises living systems as organised in such a way that they are capable to self-produce and self-maintain while in constant interaction with the environment. To apply this theoretical framework to the study of biological communication, we focus on a specific approach, based on the notion of influence, according to which communication takes place when a signal emitted by a (...)
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  29. Understanding Multicellularity: The Functional Organization of the Intercellular Space.Leonardo Bich, Thomas Pradeu & Jean-Francois Moreau - 2019 - Frontiers in Physiology 10.
    The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration, biological systems are often characterized as organized in such a way that they realize metabolic self-production and self-maintenance. The existence and activity of their components rely on the network they realize and on the continuous management of the exchange of matter and energy with their environment. (...)
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  30. SynBio 2.0, a new era for synthetic life: Neglected essential functions for resilience.Antoine Danchin & Jian Dong Huang - 2022 - Environmental Microbiology 25 (1):64-78.
    Synthetic biology (SynBio) covers two main areas: application engineering, exemplified by metabolic engi- neering, and the design of life from artificial building blocks. As the general public is often reluctant to embrace synthetic approaches, preferring nature to artifice, its immediate future will depend very much on the public’s reaction to the unmet needs created by the pervasive demands of sustainability. On the other hand, this reluctance should not have a negative impact on research that will now take into account (...)
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  31. The physiological and morphological benefits of shadowboxing.Adam M. Croom - 2023 - International Journal of Physical Education, Fitness and Sports 12 (2):8-29.
    Is shadowboxing an effective form of functional exercise? What physiological and morphological changes result from an exercise program based exclusively on shadowboxing for 3 weeks? To date, no empirical research has focused specifically on addressing these questions. Since mixed martial arts (MMA) is the fastest growing sport in the world, and since boxing and kickboxing fitness classes are among the most popular in gyms and fitness clubs worldwide, the lack of research on shadowboxing and martial arts-based fitness programs in the (...)
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  32. Biocomplexity: A pluralist research strategy is necessary for a mechanistic explanation of the "live" state.F. J. Bruggeman, H. V. Westerhoff & F. C. Boogerd - 2002 - Philosophical Psychology 15 (4):411 – 440.
    The biological sciences study (bio)complex living systems. Research directed at the mechanistic explanation of the "live" state truly requires a pluralist research program, i.e. BioComplexity research. The program should apply multiple intra-level and inter-level theories and methodologies. We substantiate this thesis with analysis of BioComplexity: metabolic and modular control analysis of metabolic pathways, emergence of oscillations, and the analysis of the functioning of glycolysis.
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  33. Three overlooked key functional classes for building up minimal synthetic cells.Antoine Danchin - 2021 - Synthetic Biology 6 (1):ysab010.
    Assembly of minimal genomes revealed many genes encoding unknown functions. Three overlooked functional categories account for some of them. Cells are prone to make errors and age. As a first key function, discrimination between proper and changed entities is indispensable. Discrimination requires management of information, an authentic, yet abstract, cur- rency of reality. For example proteins age, sometimes very fast. The cell must identify, then get rid of old proteins without destroying young ones. Implementing discrimination in cells leads to the (...)
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  34. What is Life?Guenther Witzany - 2020 - Frontiers in Astronomy and Space Sciences 7:1-13.
    In searching for life in extraterrestrial space, it is essential to act based on an unequivocal definition of life. In the twentieth century, life was defined as cells that self-replicate, metabolize, and are open for mutations, without which genetic information would remain unchangeable, and evolution would be impossible. Current definitions of life derive from statistical mechanics, physics, and chemistry of the twentieth century in which life is considered to function machine like, ignoring a central role of communication. Recent observations show (...)
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  35. Against fairness.Stephen T. Asma - 2013 - Chicago: University of Chicago Press.
    From the school yard to the workplace, there’s no charge more damning than “you’re being unfair!” Born out of democracy and raised in open markets, fairness has become our de facto modern creed. The very symbol of American ethics—Lady Justice—wears a blindfold as she weighs the law on her impartial scale. In our zealous pursuit of fairness, we have banished our urges to like one person more than another, one thing over another, hiding them away as dirty secrets of our (...)
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  36. Physiology of long pranayamic breathing: Neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system.Jerath Ravinder, James W. Edry, Vernon A. Barnes & Vandna Jerath - 2006 - Medical Hypotheses 67 (3):566-571.
    Pranayamic breathing, defined as a manipulation of breath movement, has been shown to contribute to a physiologic response characterized by the presence of decreased oxygen consumption, decreased heart rate, and decreased blood pressure, as well as increased theta wave amplitude in EEG recordings, increased parasympathetic activity accompanied by the experience of alertness and reinvigoration. The mechanism of how pranayamic breathing interacts with the nervous system affecting metabolism and autonomic functions remains to be clearly understood. It is our hypothesis that voluntary (...)
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  37. Code biology and the problem of emergence.Arran Gare - 2021 - Biosystems 208.
    It should now be recognized that codes are central to life and to understanding its more complex forms, including human culture. Recognizing the ‘conventional’ nature of codes provides solid grounds for rejecting efforts to reduce life to biochemistry and justifies according a place to semantics in life. The question I want to consider is whether this is enough. Focussing on Eigen’s paradox of how a complex code could originate, I will argue that along with Barbieri’s efforts to account for (...)
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  38. Ecological Models for Gene Therapy. II. Niche Construction, Nongenetic Inheritance, and Ecosystem Perturbations.Arnaud Pocheville, Maël Montévil & Régis Ferrière - 2014 - Biological Theory 9 (4):414-422.
    In this paper, we apply the perspective of intra-organismal ecology by investigating a family of ecological models suitable to describe a gene therapy to a particular metabolic disorder, the adenosine deaminase deficiency (ADA-SCID). The gene therapy is modeled as the prospective ecological invasion of an organ (here, bone marrow) by genetically modified stem cells, which then operate niche construction in the cellular environment by releasing an enzyme they synthesize. We show that depending on the chosen order (a choice that (...)
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  39. The theory of the organism-environment system: II. Significance of nervous activity in the organism-environment system.Timo Jarvilehto - 1998 - Integrative Physiological and Behavioral Science 33 (4):335-342.
    The relation between mental processes and brain activity is studied from the point of view of the theory of the organism-environment system. It is argued that the systemic point of view leads to a new kind of definition of the primary tasks of neurophysiology and to a new understanding of the traditional neurophysiological concepts. Neurophysiology is restored to its place as a part of biology: its task is the study of neurons as living units, not as computer chips. Neurons are (...)
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  40. Generalized Empirical Method in the Biological Sciences.Terrance Quinn - 2014 - Dialogues in Philosophy, Mental and Neuro Sciences 7 (1):31.
    Robert Henman’s article, Can brain scanning and imaging techniques contribute to a theory of thinking? came to my attention recently. My own work over the years has included applications of mathematics in the biological sciences, collaboration in experimental work in biochemistry, as well as work in the philosophy of the biological sciences. Henman suggests something that, at present, would be out of the ordinary.
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  41. Formal Biology and Compositional Biology as Two Kinds of Biological Theorizing.Rasmus Grønfeldt Winther - 2003 - Dissertation, Indiana University, Hps
    There are two fundamentally distinct kinds of biological theorizing. "Formal biology" focuses on the relations, captured in formal laws, among mathematically abstracted properties of abstract objects. Population genetics and theoretical mathematical ecology, which are cases of formal biology, thus share methods and goals with theoretical physics. "Compositional biology," on the other hand, is concerned with articulating the concrete structure, mechanisms, and function, through developmental and evolutionary time, of material parts and wholes. Molecular genetics, biochemistry, developmental biology, and physiology, which (...)
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  42. Children's Health in the Digital Age.Birgitta Dresp-Langley - 2020 - International Journal of Environmental Research and Public Health 9 (17):299..
    Can we identify potential long-term consequences of digitalisation on public health? Environmental studies, metabolic research, and state of the art research in neurobiology point towards the reduced amount of natural day and sunlight exposure of the developing child, as a consequence of increasingly long hours spent indoors online, as the single unifying source of a whole set of health risks identified worldwide, as is made clear in this review of currently available literature. Over exposure to digital environments, from abuse (...)
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  43. The Silent Voice of Those Who are no Longer: Transgenerational Transmission of Information from the Perspective of the Informational Model of Consciousness.Florin Gaiseanu - 2019 - Gerontology and Geriatrics Studies 5 (1):482-487.
    The “nature or nurture” problem concerning the debate on the innate features with respect to the acquired ones is approached in terms of information, from the perspective of the Informational Model of Consciousness. This model reveals seven distinct informational systems reflected in consciousness as informational centers, i.e. memory (Iknow-Ik), decisional info-operational center (Iwant-Iw), emotions (Ilove-Il), metabolic operations (Iam-Ia), genetic transmission (Icreate-Ic), genetic info-generation (Icreated-Icd) and the anti-entropic center (Ibelieve-Ib). Ib is a life-assisting beneficial center, because it is opposed to (...)
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  44. (2 other versions)Scientific theories as intervening representations.Thomas Mormann & Andoni Ibarra - 2006 - Theoria 21 (1):21-38.
    In this paper some classical representational ideas of Hertz and Duhem are used to show how the dichotomy between representation and intervention can be overcome. More precisely, scientific theories are reconstructed as complex networks of intervening representations (or representational interventions). The formal apparatus developed is applied to elucidate various theoretical and practical aspects of the in vivo/in vitro problem of biochemistry. Moreover, adjoint situations (Galois connections) are used to explain the relation berween empirical facts and theoretical laws in a (...)
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  45. Epigenetic Information-Body Interaction and Information-Assisted Evolution from the Perspective of the Informational Model of Consciousness.Florin Gaiseanu - 2019 - Archives in Biomedical Engineering and Biotechnology 2 (2):1-6.
    Introduction: the objective of this investigation is to analyses the advances of understanding in the epigenetic processes and to extract conclusions concerning the information-based evolution from the perspective of the Informational Model of Consciousness (IMC). Analysis of epigenetic mechanisms: it is shown that the study of the epigenetic mechanisms are of increasing interest not only to discover the responsible mechanisms of some diseases, but also to observe the acquisition and transmission mechanisms of some traits to the next generation/ transgenerations, without (...)
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  46. Computation on Information, Meaning and Representations. An Evolutionary Approach (World Scientific 2011).Christophe Menant - 2011 - In Gordana Dodig Crnkovic & Mark Burgin (eds.), Information and computation: Essays on scientific and philosophical understanding of foundations of information and computation. World Scientific. pp. 255-286.
    Understanding computation as “a process of the dynamic change of information” brings to look at the different types of computation and information. Computation of information does not exist alone by itself but is to be considered as part of a system that uses it for some given purpose. Information can be meaningless like a thunderstorm noise, it can be meaningful like an alert signal, or like the representation of a desired food. A thunderstorm noise participates to the generation of meaningful (...)
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  47. The logic of metabolism and its fuzzy consequences.A. Danchin - 2014 - Environmental Microbiology 16 (1):19-28.
    Intermediary metabolism molecules are orchestrated into logical pathways stemming from history (L-amino acids, D-sugars) and dynamic constraints (hydrolysis of pyrophosphate or amide groups is the driving force of anabolism). Beside essential metabolites, numerous variants derive from programmed or accidental changes. Broken down, variants enter standard pathways, producing further variants. Macromolecule modification alters enzyme reactions specificity. Metabolism conform thermodynamic laws, precluding strict accuracy. Hence, for each regular pathway, a wealth of variants inputs and produces metabolites that are similar to but not (...)
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  48. Gut feelings of safety: Tolerance to the microbiota mediated by innate immune receptors.Bartlomiej Swiatczak & Irun R. Cohen - 2015 - Microbiology and Immunology 59 (10):573-585.
    To enable microbial colonisation of the gut mucosa, the intestinal immune system must not only react to danger signals but also recognize cues that indicate safety. Safety recognition, paradoxically, is mediated by the same environmental sensors that are involved in signalling danger. Indeed, in addition to their well established role in inducing inflammation in response to stress signals, pattern recognition receptors (PRRs) and a variety of metabolic sensors also promote gut-microbiota symbiosis by responding to "microbial symbiosis factors", "resolution-associated molecular (...)
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  49. Remarks on the Geometry of Complex Systems and Self-Organization.Luciano Boi - 2012 - In Vincenzo Fano, Enrico Giannetto, Giulia Giannini & Pierluigi Graziani (eds.), Complessità e Riduzionismo. ISONOMIA - Epistemologica Series Editor. pp. 28-43.
    Let us start by some general definitions of the concept of complexity. We take a complex system to be one composed by a large number of parts, and whose properties are not fully explained by an understanding of its components parts. Studies of complex systems recognized the importance of “wholeness”, defined as problems of organization (and of regulation), phenomena non resolvable into local events, dynamics interactions in the difference of behaviour of parts when isolated or in higher configuration, etc., in (...)
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    L’Interpretazione Chimica del Vivente. Fondamenti sistemici delle scienze della vita.Giovanni Villani - 2023 - Bologna: Clueb.
    “La vita non è altro che chimica” e “la vita non è riducibile a chimica” sono due idee opposte dello storico problema di identificare la specificità del vivente. Sebbene siano due posizioni opposte, per entrambe la chimica è un punto di riferimento per “leggere” il vivente, è la prospettiva privilegiata in cui “interpretare” il vivente. La prospettiva di questo libro non è quella riduzionista, ma quella sistemica delle relazioni. La vita, come le altre proprietà emergenti, non si esaurisce nelle relazioni (...)
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