This article offers a critical perspective on two lines of thought in recent epistemology and philosophy of science, namely Michael Dummett?s anti-realist approach to issues of truth, meaning, and knowledge and Bas van Fraassen?s influential programme of?constructive empiricism?. While not denying the salient differences between them it shows how they converge on a sceptical outlook concerning the realist claim that truth might always transcend the restrictions of some given state of knowledge. The author puts the case that such sceptical arguments, (...) if followed through consistently, must involve giving up all claim to account for our knowledge of the growth of scientific knowledge. He also takes issue with Dummett?s idea of truth as nothing more than a matter of?warranted assertibility? and with van Fraassen?s likewise verificationist conception of empirical warrant as the most we can have by way of epistemic justification. Thus it is wrong to suppose that the realist is merely indulging in a display of? courage not under fire? when she assumes ontological commitments in excess of the observational data. This disavowal of realism in favour of a theory which?saves the appearances? has a less-than-distinguished prehistory in the range of compromise strategies adopted by upholders of a dominant metaphysics or world-view, starting out with the orthodox Catholic attempt to defuse the implications of the heliocentric hypothesis advanced by Copernicus and Galileo. Such theological motives are nowadays not so prominent although? it is suggested fithey do emerge at certain points in Dummett?s writing. More constructively, this article presents a case for objectivism with regard to scientific truth and also for inference to the best causal explanation on both the micro- and the macrophysical scale as the only approach with an adequate claim to make sense of the history of advancements in scientific knowledge to date. (shrink)

Philosophical discussions of biological classification have failed to recognise the central role of homology in the classification of biological parts and processes. One reason for this is a misunderstanding of the relationship between judgments of homology and the core explanatory theories of biology. The textbook characterisation of homology as identity by descent is commonly regarded as a definition. I suggest instead that it is one of several attempts to explain the phenomena of homology. Twenty years ago the ‘new experimentalist’ movement (...) in philosophy of science drew attention to the fact that many experimental phenomena have a ‘life of their own’: the conviction that they are real is not dependent on the theories used to characterise and explain them. I suggest that something similar can be true of descriptive phenomena, and that many homologies are phenomena of this kind. As a result the descriptive biology of form and function has a life of its own—a degree of epistemological independence from the theories that explain form and function. I also suggest that the two major ‘homology concepts’ in contemporary biology, usually seen as two competing definitions, are in reality complementary elements of the biological explanation of homology. (shrink)

Van Fraassen does not argue that everyone should be a constructive empiricist. He claims only that constructive empiricism (CE) is a coherent post-positivist alternative to realism, notwithstanding the realist's charge that CE is arbitrary and irrational. He does argue, however, that the empiricist is obliged to limit belief as CE prescribes. Criticism of CE has been largely directed at van Fraassen's claim that CE is a coherent option. Far less attention has been directed at his claim that empiricists should be (...) constructive empiricists. I consider his various attempts to support this claim, conclude that they are unsuccessful, and suggest that the empiricist who repudiates CE does not thereby abandon contemporary empiricism itself. (shrink)

Relying on the notion of “overlapping perspectives,” this paper argues that entity realism and perspectivism are complementary. According to entity realism, it is justified to maintain a positive attitude toward the existence of unobservable entities with which multiple experimental interactions are possible. Perspectivism also explains that our beliefs about these entities are bounded by historically contingent theoretical and instrumental perspectives. The argument of the paper is developed through a discussion of Ronald Giere’s versions of realism: entity realism, constructive realism, and (...) perspectival realism. (shrink)

This paper defends a Hackingian approach to the scientific realism debate by arguing against mainstream realists’ and antirealists’ common claim that no experimental arguments for the reality of posited entities can be theory-independent. Opposing this claim, I argue that some experimental arguments can warrant belief in the existence of entities without depending on the truth of the theories that posit the entities and describe their properties and the theories that explain the interactions between the entities and the experimental devices. To (...) achieve this goal, I investigate Hacking’s case of electron spraying, the famous experiment of positioning atoms by means of a scanning tunnelling microscope, and some novel experiments that use Ashkin’s optical tweezers. By introducing the distinction between theoretical properties and ontic properties, I argue that we can build up some theory-independent criteria of reality on the basis of ontic properties. Manipulability is an ontic property and the manipulation criterion is thus a theory-independent one, which should be reexamined and used for those experimental cases along a local approach to the realism debate. Resisting the mainstream realists’ and antirealists’ objections, I contend that some experiments using optical tweezers can warrant belief in the existence of the experimented entities without depending on theories. (shrink)

Dieses Grundlagenwerk soll die Fundamente der Erkenntnistheorie und philosophischen Ethik vollständig neu herleiten, sowie den aktuellen Forschungsstand auf einen wahren Kern herunterbrechen und kritisch zusammenfassen. Im Zentrum steht dabei die Frage, inwiefern Erkenntnis der Wirklichkeit möglich ist, sowie die Suche nach elementaren, rationalen Rechtfertigungen, auf denen jegliche Erkenntnis aufbaut. Über fünfzehn Jahre hinweg habe ich dazu das Rechtfertigungsproblem ergründet, sowie herkömmliche Theorien und Argumentationen umfassend analysiert. Mit diesem Grundlagenwerk will ich einen voraussetzungsfreien, vollständig hergeleiteten Erkenntnisstand schaffen und ihn auf ein (...) sicheres Fundament stellen. Mein Ziel ist es, eine moderne Erkenntnistheorie aufzustellen, die eine vollständige Rechtfertigung auf allen Ebenen liefern kann. ––––––––––––––– Programm (mit fachlichen Begrifflichkeiten): Der erkenntnistheoretische Teil untersucht die ontologischen Fragen des Realismus von Wirklichkeit und Bewusstsein. Die physikalische Wirklichkeit scheint sich fundamental und damit auch ontologisch von (phänomenalen) Bewusstsein zu unterscheiden, und dieses zu determinieren (psychophysische Supervenienz; Epiphänomenalismus). Es wird untersucht, ob sich die Realismus-Hypothese der Wirklichkeit aus selbstevidenten Basisüberzeugungen einer Fundierungstheorie (unseren momentanen Bewusstseinsinhalten) und fundamentalen Schlussmethoden rational begründen lässt (instrumentalistische Rechtfertigung). Die Existenz und Erkennbarkeit der Wirklichkeit könnte dabei logisch aus einem intuitiven, direkten Realismus übertragen werden (realistische Rechtfertigung). Unsere fundamentalen Schlussmethoden, um von Gegebenen auf Unbekanntes zu schließen, lassen sich als bestimmte Arten von Induktion und Abduktion identifizieren, deren herkömmliche Begründungsversuche untersucht werden. So werden unsere induktiven, abduktiven, rationalen und logischen Grundlagen für Erkenntnisse, Annahmen und Theorien untersucht. Da Überzeugungen über Basisüberzeugungen hinaus immer unsicher sind, muss ihre Rechtfertigung nach dem Regressproblem in fundamentalen Schlüssen bzw. Rechtfertigungen enden, die schlicht gegeben sind, und nicht weiter gerechtfertigt werden können. Es zeigt sich, dass diese Schlüsse (bzw. Rechtfertigungen von nicht-Gegebenen) möglicherweise unserer fundamentalen intuitiven Rationalität bzw. Logik entspringen (Intuitionismus) – bzw. nur dadurch gerechtfertigt werden können, dass sie dieser entsprechen. (Dies entspricht einer intuitionistisch bzw. internalistisch-naturalistisch erweiterten Fundierungstheorie.) Diese rein idealistische Argumentation, wird durch die Annahme, dass wir in einer physikalischen Wirklichkeit leben, „bestätigt“, da unser gesamtes Denken letztlich durch die Strukturen unseres Gehirns determiniert ist (Evolutionäre Erkenntnistheorie). Abduktion und Induktion scheinen der rational alternativlosen, fundamentalen kognitiven Disposition zu entspringen, Gleichheiten bzw. sich wiederholende Unterschiede zusammenzufassen, und logische Verknüpfungen zu erkennen. Dies entspricht einer Reduktion gegebener Evidenz auf einen Informationsgehalt. Die realistische Rechtfertigung von Abduktion und auf ihr basierender Induktion scheint ebenfalls aus unserer fundamentalen Rationalität zu entspringen, und in ihrer Überzeugungsstärke an die Stärke der reduktiven Abduktivität gekoppelt zu sein. So nehmen wir reale, notwendige, induktiv fortgesetzte Gesetzmäßigkeiten an. Jeder externalistische Erkenntnisanspruch scheint nur internalistisch gerechtfertigt werden zu können. Auch eine Rechtfertigung mittels Kohärenz (Kohärentismus) scheint auf Abduktion zu gründen. Die alltäglichen Verwendungen der Begriffe Wahrheit und Wissen verweisen aufgrund ihrer verschiedenen, aufeinander aufbauenden, fehlbaren Rechtfertigungsarten bzw. -stärken auf einen Kontextualismus des Begriffs der Rechtfertigung. Wahrheit und Wissen scheinen also möglicherweise für ein Subjekt nur unvollständig gerechtfertigt sein zu müssen, bis die Unvollständigkeit bzw. Fehlbarkeit ihrer Rechtfertigung begründet aufgezeigt wird (Epistemic Conservatism). Der Teil zur philosophischen Ethik untersucht das Konzept der Normativität und ethische Begriffe wie das Sollen, der Wertung und das Gute. Ethische/moralische Inhalte werden hinsichtlich ihrer Ontologie, Bedeutung, Wahrheit und Objektivität untersucht. Dazu zählt eine Analyse ethischer Theorien und Konzepte, wie Sensualismus, Subjektivismus, Relativismus, Realismus, Teleologie, Deontologie, Utilitarismus und moralischer Status. Dabei wird unter anderem geklärt, ob normative Fragen letztlich in kausalen Fakten gründen müssen (Naturalismus, Nonkognitivismus), also insofern rein beschreibend beantwortet werden können. Zuletzt wird eine präzise Definition des Begriffs der Gerechtigkeit aufgestellt. (shrink)

I identify two versions of the scientific anti-realist’s selectionist explanation for the success of science: Bas van Fraassen’s original and K. Brad Wray’s newer interpretation. In Wray’s version, psycho-social factors internal to the scientific community – viz. scientists’ interests, goals, and preferences – explain the theory-selection practices that explain theory-success. I argue that, if Wray’s version were correct, then science should resemble art. In art, the artwork-selection practices that explain artwork-success appear faddish. They are prone to radical change over time. (...) Theory-selection practices that explain theory-success in science are however not faddish. They are mostly stable; that is, long-lived and consistent over time. This is because scientists (explicitly or implicitly) subscribe to what I will call the testability norm: scientific theories must make falsifiable claims about the external physical world. The testability norm and not psycho-sociology explains the theory-selection practices that explain theory-success in science. Contra Wray, scientific anti-realists can then maintain that the external physical world (as expressed in the testability norm) explains theory-success. (shrink)

This paper draws on the phenomenological-hermeneutical approaches to philosophy of science to develop realist perspectivism, an integration of experimental realism and perspectivism. Specifically, the paper employs the distinction between “manifestation” and “phenomenon” and it advances the view that the evidence of a real entity is “explorable” in order to argue that instrumentally-mediated robust evidence indicates real entities. Furthermore, it underpins the phenomenological notion of the horizonal nature of scientific observation with perspectivism, so accounting for scientific pluralism even in the cases (...) of inconsistent models. Overall, realist perspectivism is proposed as the way to go for (phenomenologically-hermeneutically minded) philosophers of science. (shrink)

According to constructive empiricists, accepting a scientific theory involves belief only that it is true of the observable world, where observability is defined in terms of what is detectable by the unaided senses. On this view, scientific instruments are machines that generate new observable data, but this data need not be interpreted as providing access to a realm of phenomena beyond what is revealed by the senses. A recent challenge to the constructive empiricist account of instruments appeals to the extended (...) mind thesis, according to which cognitive processes are sometimes constituted not just by brain activity, but can extend into the rest of the body and the surrounding environment. If this is right, scientific instruments may, in the right circumstances, literally become part of our perceptual processes. In this article, I examine this extended perception argument, and I find that it fails for the vast majority of scientific instruments. Even if the extended mind thesis is accepted, the constructive empiricist can draw a line between observables and unobservables that makes very few concessions to the realist. (shrink)

This dissertation is about human knowledge of reality. In particular, it argues that scientific knowledge is bounded by historically available instruments and theories; nevertheless, the use of several independent instruments and theories can provide access to the persistent potentialities of reality. The replicability of scientific observations and experiments allows us to obtain explorable evidence of robust entities and properties. The dissertation includes seven chapters. It also studies three cases – namely, Higgs bosons and hypothetical Ϝ-particles (section 2.4), the Ptolemaic and (...) Kepler model of the planets (section 6.7), and the special theory of relativity (chapter 7). -/- Chapter 1 is the introduction of the dissertation. Chapter 2 clarifies the notion of the real on the basis of two concepts: persistence and resistance. These concepts enable me to explain my ontological belief in the real potentialities of human-independent things and the implications of this view for the perceptual and epistemological levels of discussion. On the basis of the concept of “overlapping perspectives”, chapter 3 argues that entity realism and perspectivism are complementary. That is, an entity that manifests itself through several experimental/observational methods is something real, but our knowledge of its nature is perspectival. Critically studying the recent views of entity realism, chapter 4 extends the discussion of entity realism and provides a criterion for the reality of property tokens. Chapter 5, in contrast, develops the perspectival aspects of my view on the basis of the phenomenological-hermeneutical approaches to the philosophy of science. This chapter also elaborates my view of empirical evidence, as briefly expressed in sections 2.5 and 4.5. Chapter 6 concerns diachronic theoretical perspectives. It first explains my view of progress, according to which current perspectives are broader than past ones. Second, it argues that the successful explanations and predictions of abandoned theories can be accounted for from our currently acceptable perspectives. The case study of Ptolemaic astronomy supports the argument of this chapter. Chapter 7 serves as the conclusion of the dissertation by applying the central themes of the previous chapters to the case study of special relativity theory. I interpret frame-dependent properties, such as length and time duration, and the constancy of the speed of light according to realist perspectivism. (shrink)

Kendall Walton argues that photographs are transparent; we literally see the things depicted in them, not just the depictions. This intriguing claim has endured numerous criticisms from those I call the ‘egocentrists’, according to whom seeing—literal seeing—requires the conveyance of egocentric information; to count as seeing something, a visual experience of that thing must impart some information, however spare, about its position relative to the viewer. Since photographs fail to convey such information, the egocentrists claim, Walton’s transparency thesis fails. This (...) paper considers several ways this egocentric condition on seeing has been developed and shows that none of them is persuasive. Seeing, I argue, does not require the conveyance of egocentric information. As such, and barring other problems, Walton’s transparency thesis stands. The paper closes with a speculative discussion of the kinds of empirical and action-guiding considerations that motivate egocentrism. (shrink)

What kinds of norms constrain mechanistic discovery and explanation? In the mechanistic literature, the norms for good explanations are directly derived from answers to the metaphysical question of what explanations are. Prominent mechanistic accounts thus emphasize either ontic or epistemic norms. Still, mechanistic philosophers on both sides agree that there is no sharp distinction between the processes of discovery and explanation. Thus, it seems reasonable to expect that ontic and epistemic accounts of explanation will be accompanied by ontic and epistemic (...) accounts of discovery, respectively. As we will show here, however, recent discovery accounts implicitly rely on both ontic and epistemic norms to characterize the discovery process. In this paper, we develop an account that makes explicit that, and how, ontic and epistemic norms work together throughout the discovery process. By describing mechanism discovery as a process of pattern recognition we demonstrate that scientists have to develop epistemic activities to distinguish a pattern from its background. Furthermore, they have to determine which epistemic activities successfully describe how the pattern is implemented by identifying the pattern’s components. Our approach reveals that ontic and epistemic norms are equally important in mechanism discovery. (shrink)

This groundbreaking, open access volume analyses and compares data practices across several fields through the analysis of specific cases of data journeys. It brings together leading scholars in the philosophy, history and social studies of science to achieve two goals: tracking the travel of data across different spaces, times and domains of research practice; and documenting how such journeys affect the use of data as evidence and the knowledge being produced. The volume captures the opportunities, challenges and concerns involved in (...) making data move from the sites in which they are originally produced to sites where they can be integrated with other data, analysed and re-used for a variety of purposes. The in-depth study of data journeys provides the necessary ground to examine disciplinary, geographical and historical differences and similarities in data management, processing and interpretation, thus identifying the key conditions of possibility for the widespread data sharing associated with Big and Open Data. The chapters are ordered in sections that broadly correspond to different stages of the journeys of data, from their generation to the legitimisation of their use for specific purposes. Additionally, the preface to the volume provides a variety of alternative “roadmaps” aimed to serve the different interests and entry points of readers; and the introduction provides a substantive overview of what data journeys can teach about the methods and epistemology of research. (shrink)

To study consciousness, scientists need to determine when participants are conscious and when they are not. They do so with consciousness detection procedures. A recurring skeptical argument against those procedures is that they cannot be calibrated: there is no way to make sure that detection outcomes are accurate. In this article, I address two main skeptical arguments purporting to show that consciousness scientists cannot calibrate detection procedures. I conclude that there is nothing wrong with calibration in consciousness science.

The evolution of gravitational tests from an epistemological perspective framed in the concept of rational reconstruction of Imre Lakatos, based on his methodology of research programmes. Unlike other works on the same subject, the evaluated period is very extensive, starting with Newton's natural philosophy and up to the quantum gravity theories of today. In order to explain in a more rational way the complex evolution of the gravity concept of the last century, I propose a natural extension of the methodology (...) of the research programmes of Lakatos that I then use during the paper. I believe that this approach offers a new perspective on how evolved over time the concept of gravity and the methods of testing each theory of gravity, through observations and experiments. I argue, based on the methodology of the research programmes and the studies of scientists and philosophers, that the current theories of quantum gravity are degenerative, due to the lack of experimental evidence over a long period of time and of self-immunization against the possibility of falsification. Moreover, a methodological current is being developed that assigns a secondary, unimportant role to verification through observations and/or experiments. For this reason, it will not be possible to have a complete theory of quantum gravity in its current form, which to include to the limit the general relativity, since physical theories have always been adjusted, during their evolution, based on observational or experimental tests, and verified by the predictions made. Also, contrary to a widespread opinion and current active programs regarding the unification of all the fundamental forces of physics in a single final theory, based on string theory, I argue that this unification is generally unlikely, and it is not possible anyway for a unification to be developed based on current theories of quantum gravity, including string theory. In addition, I support the views of some scientists and philosophers that currently too much resources are being consumed on the idea of developing quantum gravity theories, and in particular string theory, to include general relativity and to unify gravity with other forces, as long as science does not impose such research programs. -/- DOI: 10.13140/RG.2.2.35350.70724 . (shrink)

Evoluția testelor gravitaționale dintr-o perspectivă epistemologică încadrată în conceputul de reconstrucție rațională al lui Imre Lakatos, pe baza metodologiei acestuia a programelor de cercetare. Perioada evaluată este foarte vastă, începând cu filosofia naturală a lui Newton și până la teoriile gravitației cuantice din zilele noastre. Pentru a explica mai rațional evoluția complexă a conceptului de gravitație din ultimul secol, propun o extindere naturală a metodologiei programelor de cercetare pe care o folosesc apoi pe parcursul lucrării. Consider că această abordare oferă (...) o nouă perspectivă asupra modului în care au evaluat în timp conceptul de gravitație și metodele de testare a fiecărei teorii a gravitației, prin observații și experimente. Argumentez, pe baza metodologiei programelor de cercetare și a studiilor oamenilor de știință și filosofilor, că actualele teorii ale gravitației cuantice sunt degenerative, datorită lipsei dovezilor experimentale pe o perioadă îndelungată de timp și a auto-imunizării împotriva posibilității falsificării. Mai mult, în prezent este în curs de dezvoltare un curent metodologic care atribuie un rol secundar, neimportant, verificărilor prin observații și/sau experimente. Din această cauză, nu va fi posibilă o teorie completă a gravitației cuantice în forma actuală care să includă la limită relativitatea generală, întrucât teoriile fizice au fost dintotdeauna ajustate, în decursul evoluției lor, pe baza testelor observaționale sau experimentale, și verificate prin predicțiile făcute. De asemenea, contrar unei opinii răspândite și a unor programe active actuale privind unificarea tuturor forțelor fundamentale ale fizicii într-o singură teorie finală, pe baza teoriei corzilor, argumentez că este puțin probabil în general să se realizeze această unificare, și nu este posibil oricum ca unificarea să se elaboreze pe baza teoriilor actuale ale gravitației cuantice, inclusiv prin teoria corzilor. În plus, susțin punctele de vedere ale unor oameni de știință și filosofi că în prezent se consumă mult prea multe resurse pe ideea dezvoltării teoriilor gravitației cuantice, și în special teoria corzilor, care să includă relativitatea generală și să unifice gravitația cu celelalte forțe, în condițiile în care știința nu impune astfel de programe de cercetare. -/- DOI: 10.13140/RG.2.2.14582.75842 . (shrink)

Although scientific realism is the default position in the life sciences, philosophical accounts of realism are geared towards physics and run into trouble when applied to fields such as biology or neuroscience. In this paper, I formulate a new robustness-based version of entity realism, and show that it provides a plausible account of realism for the life sciences that is also continuous with scientific practice. It is based on the idea that if there are several independent ways of measuring, detecting (...) or deriving something, then we are justified in believing that it is real. I also consider several possible objections to robustness-based entity realism, discuss its relationship to ontic structural realism, and show how it has the potential to provide a novel response to the pessimistic induction argument. (shrink)

Debates about scientific realism are closely connected to almost everything else in the philosophy of science, for they concern the very nature of scientific knowledge. Scientific realism is a positive epistemic attitude toward the content of our best theories and models, recommending belief in both observable and unobservable aspects of the world described by the sciences. This epistemic attitude has important metaphysical and semantic dimensions, and these various commitments are contested by a number of rival epistemologies of science, known collectively (...) as forms of scientific antirealism. This article explains what scientific realism is, outlines its main variants, considers the most common arguments for and against the position, and contrasts it with its most important antirealist counterparts. (shrink)

En sciences sociales, les scientifiques utilisent les rapports des sujets sur leurs propres états mentaux dans leurs démarches expérimentales. Ainsi, l’introspection, ou la capacité des sujets à former des croyances sur leurs propres états mentaux, y joue un rôle important. Selon les tenants de l’introspectionnisme, l’introspection est une méthode, certes privée, mais qui permet de justifier directement des hypothèses scientifiques. Ainsi, contrairement aux méthodes utilisées dans les sciences de la nature qui se fondent uniquement sur des données publiques, les sciences (...) sociales utiliseraient des données subjectives pour justifier leurs hypothèses. Contre l’introspectionnisme, nous défendons que l’introspection n’est pas utilisée pour justifier directement les hypothèses, mais que sa place est plutôt similaire à celle d’un instrument de mesure des états et processus mentaux des sujets, susceptible d’être calibré, à la façon dont les instruments de mesure utilisés dans les sciences... (shrink)

Stojnić et al. (2013, 2017) argue that the reference of demonstratives is fixed without any contribution from the extra-linguistic context. On their `prominence/coherence' theory, the reference of a demonstrative expression depends only on its context-independent linguistic meaning. Here, we argue that Stojnić et al.’s striking claims can be maintained in only the thinnest technical sense. Instead of eliminating appeals to the extra-linguistic context, we show how the prominence/coherence theory merely suppresses them. Then we ask why one might be tempted to (...) try and offer such a view. Since we are rather sympathetic to the motivations we find, we close by sketching a more plausible alternative. (shrink)

This article examines what realists and anti-realist debates are all about. Through presenting the core of the main arguments in these debates, these are significant arguments and they are the kind of arguments that can clarify what it meant by ‘truth’ between Realist and anti-realist in general. The concluding remark is that though the main anti- realist’s arguments in these debates can be seen as some powerful arguments through raising questions on the relationship between theory and evidence, success and truth. (...) However, the success of science and the use of science in everyday life has not been given any satisfactory explanations by the anti-realists nor the use of it has been shut out from the daily life by these arguments against it. (shrink)

As for most measurement procedures in the course of their development, measures of consciousness face the problem of coordination, i.e., the problem of knowing whether a measurement procedure actually measures what it is intended to measure. I focus on the case of the Perceptual Awareness Scale to illustrate how ignoring this problem leads to ambiguous interpretations of subjective reports in consciousness science. In turn, I show that empirical results based on this measurement procedure might be systematically misinterpreted.

In psychiatry, pharmacological research has played a crucial role in the formulation, revision, and refinement of neurobiological theories of psychopathology. Besides being utilized as potential treatments for various mental disorders, pharmacological drugs play an important epistemic role as experimental instruments that help scientists uncover the neurobiological underpinnings of mental disorders (Tsou, 2012). Interventions with psychiatric patients using pharmacological drugs provide researchers with information about the neurobiological causes of mental disorders that cannot be obtained in other ways. This important source of (...) evidence for the biological causes of mental disorder is often overlooked in philosophical analyses of psychiatry, especially in skeptical analyses that debase the biological aspects of psychopathology (e.g., Szasz, 1960; Scheff, 1963; Laing, 1967). In discussing pharmacological interventions as a form of evidence for the physical basis of mental disorders, this paper aims to clarify the nature, reliability, and limitations of this evidence. In addition, it illustrates the central role that pharmacological findings in applied clinical contexts play in the acquisition of neurobiological knowledge in research contexts. (shrink)

Our best social scientific theories try to tell us something about the social world. But is talk of a “social world” a metaphor that we ought not take too seriously? In particular, do the denizens of the social world—cultural values like the Protestant work ethic, firms like ExxonMobil, norms like standards of dress and behavior, institutions like the legal system, teams like FC Barcelona, conventions like marriages—exist? The question is not merely academic. Social scientists use these different social entities to (...) explain social phenomena such as the rise of capitalism, the decline in oil prices, or the effect of unions on the sports labor market. But how could these explanations possibly work if social entities don’t exist? (shrink)

In many scientific fields, today’s practices of empirical enquiry rely heavily on the production of images that display the investigated phenomena. And while scientific images of phenomena have been important for a long time, what is striking now is that scientists have found ways to visualize such widely different types of phenomena. In the past twenty or thirty years, we have become accustomed to seeing images of galaxies, of cells, of the human brain but also of blood flow or of (...) turbulent fluids. This success in making images relies first on the set of imaging devices that have flourished in the twentieth century, instruments such as radio-telescopes, electronic microscopes, MRI and many more. Without these... (shrink)

[M]y attention was drawn to the flower garden of the grey matter, which contained cells with delicate and elegant forms, the mysterious butterflies of the soul, the beating of whose wings may someday... clarify the secret of mental life. Art can actually facilitate scientific understanding, even discovery. Art can be, and has been, the entryway to vision and the understanding of natural phenomena as demonstrated in its role in the development of neuron theory. While developing a course on current brain (...) research and learning and then projects for S.T.E.A.M. curriculum, I was repeatedly drawn to the work of Santiago Ramon y Cajal, whose life work provides an extraordinary example of the.. (shrink)

In this paper, I argue that Constructive Empiricism (CE) is ambiguous between two interpretations: CE as a normative epistemology of science and CE as a descriptive philosophy of science. When they present CE, constructive empiricists write as if CE is supposed to be more than a normative epistemology of science and that it is meant to be responsible to actual scientific practices. However, when they respond to objections, constructive empiricists fall back on a strictly normative interpretation of CE. This ambiguity (...) seems to make CE immune to objections in a rather ad hoc fashion. (shrink)

This thesis offers a naturalist revision of Alain Badiou’s philosophy. This goal is pursued through an encounter of Badiou’s mathematical ontology and theory of truth with contemporary trends in philosophy of mathematics and philosophy of science. I take issue with Badiou’s inability to elucidate the link between the empirical and the ontological, and his residual reliance on a Heideggerian project of fundamental ontology, which undermines his own immanentist principles. I will argue for both a bottom-up naturalisation of Badiou’s philosophical approach (...) to mathematics and a top-down naturalisation. Articulating my particular understanding of what realism and naturalism should commit us to, I propose a creative fusion of Badiou’s attention to metamathematical results with a structural-informational metaphysics, proposing a ‘matherialism’ uniting the more daring speculative insights of the former with the naturalist and empiricist commitments motivating the latter. (shrink)

The question about the scientific nature of computing has been widely debated with no universal consensus reached about its disciplinary status. Positions vary from acknowledging computing as the science of computers to defining it as a synthetic engineering discipline. In this paper, we aim at discussing the nature of computing from a methodological perspective. We consider, in particular, the nature and role of experiments in this field, whether they can be considered close to the traditional experimental scientific method or, instead, (...) they possess peculiar and unique features. We argue that this experimental perspective should be taken into account when discussing the status of computing. We critically survey how the experimental method has been conceived and applied in computing, and some open issues that could be tackled with the aid of the history of science, the philosophy of science, and the philosophy of technology. (shrink)

I offer a meta-level analysis of realist arguments for the reliability of ampliative reasoning about the unobservable. We can distinguish form-driven and content-driven arguments for realism: form-driven arguments appeal to the form of inductive inferences, whilst content-driven arguments appeal to their specific content. After regimenting the realism debate in these terms, I will argue that the content-driven arguments are preferable. Along the way I will discuss how my analysis relates to John Norton’s recent, more general thesis that the grounds for (...) licit induction are always material. (shrink)

Abstract If we take for granted that introspection is indispensable for the study of conscious mental states, the question arises what criteria have to be met in order for introspective reports to qualify as scientific evidence. There have been some attempts to argue (implicitly or explicitly) that it is possible to provide a satisfactory answer to this question while remaining agnostic with respect to questions about the nature of consciousness. Focusing on the aim of using introspection in order to generate (...) phenomenological descriptions of conscious mental states, this paper argues that such an agnostic stance cannot be maintained, because the very meaning of ?introspection? remains fuzzy as long as we don't have a clear understanding of how the mind does it. I show that current debates revolve around some of the same issues that were already in the background of debates around 1900, and I argue that a satisfactory treatment of introspection as a method cannot be separated from the aim of providing a satisfactory treatment of introspection as a feature of consciousness. (shrink)

In psychiatry, pharmacological drugs play an important experimental role in attempts to identify the neurobiological causes of mental disorders. Besides being developed in applied contexts as potential treatments for patients with mental disorders, pharmacological drugs play a crucial role in research contexts as experimental instruments that facilitate the formulation and revision of neurobiological theories of psychopathology. This paper examines the various epistemic functions that pharmacological drugs serve in the discovery, refinement, testing, and elaboration of neurobiological theories of mental disorders. I (...) articulate this thesis with reference to the history of antipsychotic drugs and the evolution of the dopamine hypothesis of schizophrenia in the second half of the twentieth century. I argue that interventions with psychiatric patients through the medium of antipsychotic drugs provide researchers with information and evidence about the neurobiological causes of schizophrenia. This analysis highlights the importance of pharmacological drugs as research tools in the generation of psychiatric knowledge and the dynamic relationship between practical and theoretical contexts in psychiatry. (shrink)

Constructive empiricism - as formulated by Bas van Fraassen - makes no epistemological claims about the nature of science. Rather, it is a view about the aim of science, to be situated within van Fraassen's broader voluntarist epistemology. Yet while this epistemically minimalist framework may have various advantages in defending the epistemic relevance of constructive empiricism, I show how it also has various disadvantages in maintaining its internal coherence.

The last two decades have seen a rising interest in (a) the notion of a scientific phenomenon as distinct from theories and data, and (b) the intricacies of experimentally producing and stabilizing phenomena. This paper develops an analysis of the stabilization of phenomena that integrates two aspects that have largely been treated separately in the literature: one concerns the skills required for empirical work; the other concerns the strategies by which claims about phenomena are validated. I argue that in order (...) to make sense of the process of stabilization, we need to distinguish between two types of phenomena: phenomena as patterns in the data ( surface regularities ) and phenomena as underlying (or hidden ) regularities. I show that the epistemic relationships that data bear to each of these types of phenomena are different: Data patterns are instantiated by individual data, whereas underlying regularities are indicated by individual data, insofar as they instantiate a data pattern. Drawing on an example from memory research, I argue that neither of these two kinds of phenomenon can be stabilized in isolation. I conclude that what is stabilized when phenomena are stabilized is the fit between surface regularities and hidden regularities. (shrink)

The introduction of electron microscopy profoundly altered biomedical research, providing a tool for a more detailed but at the same time a spatially and temporally more restricted visual analysis. Examining the case study of Golgi apparatus research in the 1950s and 1960s, it will be shown how microscopists handled these challenges, and how these confrontations modified the general concept of cellular organization. This will also shed light on the artifact debate and on the question of scientific realism in the field (...) of microscopy. (shrink)

In this paper I discuss the rule of inference proposed by Kuipers under the name of Inference to the Best Theory. In particular, I argue that the rule needs to be strengthened if it is to serve realist purposes. I further describe a method for testing, and perhaps eventually justifying, a suitably strengthened version of it.

Ever since Hilary Putnam claimed that a realist philosophy is “the only philosophy that doesn’t make the success of science a miracle,” explanations for the success of science have proliferated in the philosophical literature (Putnam 1975, p. 73). Realists argue that the success of science, as exhibited by our ability to accurately predict and explain a wide range of phenomena, indicates that our theories have identified some of the underlying causal structures of the world (e.g., Boyd 1985, Ellis 1985, McMullin (...) 1984, Salmon 1984). Nonrealists counter that success cannot provide a warrant for belief in the truth of scientific theories because there have been successful theories in the past that are now believed to be false (Laudan 1981b). Instead, they offer a naturalized account whereby our theories are designed to be successful predictors and only those which fulfill this goal survive (Laudan 1987, van Fraassen, 1980). (shrink)

The use of multiple means of determination to “triangulate” on the existence and character of a common phenomenon, object, or result has had a long tradition in science but has seldom been a matter of primary focus. As with many traditions, it is traceable to Aristotle, who valued having multiple explanations of a phenomenon, and it may also be involved in his distinction between special objects of sense and common sensibles. It is implicit though not emphasized in the distinction between (...) primary and secondary qualities from Galileo onward. It is arguably one of several conceptions involved in Whewell’s method of the “consilience of inductions” (Laudan 1971) and is to be found in several places in Peirce. (From M. Brewer and B. Collins, eds., (1981); Scientific Inquiry in the Social Sciences (a festschrift for Donald T. Campbell), San Francisco: Jossey-Bass, pp. 123–162.). (shrink)

RESUMO Neste artigo pretendo expor sinteticamente os problemas levantados contra uma das formas de realismo científico conhecida como realismo experimental, além de propor uma formulação mais aceitável do mesmo, resistente a tais críticas. Os problemas alegados pelos oponentes do realismo experimental variam desde a acusação de inadequação em relação à prática da comunidade científica, até a inconsistência ao admitir entidades e propriedades postuladas teoricamente recusando, entretanto, as teorias em que tais entidades e propriedades aparecem. Some-se a essas críticas a de (...) que o próprio critério do realismo de entidades seria implausível, seja porque falha na produção de crenças verdadeiras ou porque não fornece garantias melhores do que outras formas de realismo científico. Argumentarei que, adotando o realismo experimental exclusivamente como um critério epistêmico e aplicando tal critério às propriedades é possível contornar as críticas, reabilitando uma proposta realista que muitos consideravam já descartada. ABSTRACT In this paper, I will expose briefly the problems raised against one kind of scientific realism known by experimental realism and also will propose an acceptable formulation of that realism, resistant to those criticisms. The problems claimed by the experimental realism’s opponents range from the accusation of inadequacy with the scientific community’s practice to the claim that the admission of entities and proprieties without accepting the theories in which those proprieties and entities are supposed is incoherent. Besides, there is another criticism which states that the entities realism’s criterion is implausible, either because it fails to produce true beliefs or because there is no better warranty in adopting it than other kinds of scientific realism. I will argue that adopting experimental realism exclusively as an epistemic criterion and applying that criterion to proprieties it is possible to escape the criticisms, rehabilitating a realist propose that many people though already discarded. (shrink)

Martin Kusch has recently defended Bas van Fraassen’s controversial view on microscopes, according to which these devices are not ‘windows on an invisible world’, but rather ‘image generators’. The two authors also claim that, since in a microscopic detection it is not possible to empirically investigate the geometrical relations between all the elements involved, one is entitled to maintain an agnostic stance about the reality of the entity allegedly represented by the produced image. In this paper I argue that, contrary (...) to what Kusch maintains, this might not be a neutral way to render scientific evidence. Moreover, a constructive empiricist can support a realist interpretation of microscopic images. In fact, constructive empiricism and van Fraassen’s own anti-realism do not necessarily amount to the same thing. (shrink)

This book analyses the impact computerization has had on contemporary science and explains the origins, technical nature and epistemological consequences of the current decisive interplay between technology and science: an intertwining of formalism, computation, data acquisition, data and visualization and how these factors have led to the spread of simulation models since the 1950s. -/- Using historical, comparative and interpretative case studies from a range of disciplines, with a particular emphasis on the case of plant studies, the author shows how (...) and why computers, data treatment devices and programming languages have occasioned a gradual but irresistible and massive shift from mathematical models to computer simulations. -/- . (shrink)

Bachelard regarded the scientific changes that took place in the early twentieth century as the beginning of a new era, not only for science, but also for philosophy. For him, the theory of relativity and quantum mechanics had shown that a new philosophical ontology and a new epistemology were required. I show that the type of philosophy with which he was more closely associated, in particular that of Léon Brunschvicg, offered to him a crucial starting point. Brunschvicg never considered scientific (...) objects as independent of the mind, and as a consequence questions such as the existence of particles independently of the mind, theory or apparatus, were absent from his philosophy, which was rather aimed at analyzing the mind critically, and above all historically. Bachelard accepted the fundamental ideas of Brunschvicg’s philosophy; however, his own reading of contemporary science enabled him to go beyond it, as shown by his emphasis on the social production of knowledge, and by his removal of the distinction between ideas and technologically produced objects of knowledge. For him, modern science teaches philosophy that knowledge is not a phenomenology but rather a ‘phenomenotechnique’. I argue that Bachelard’s view that philosophy ‘should follow science’ stems from moral considerations.Keywords: Gaston Bachelard; Léon Brunschvicg; Phenomenotechnique; Chosisme; Theory of relativity; Quantum mechanics. (shrink)

State of the art paper on the topic realism/anti-realism. The first part of the paper elucidates the notions of existence and independence of the metaphysical characterization of the realism/anti-realism dispute. The second part of the paper presents a critical taxonomy of the most important positions and doctrines in the contemporary literature on the domains of science and mathematics: scientific realism, scientific anti-realism, constructive empiricism, structural realism, mathematical Platonism, mathematical indispensability, mathematical empiricism, intuitionism, mathematical fictionalism and second philosophy.

Inference to the Best Explanation has become the subject of a livelydebate in the philosophy of science. Scientific realists maintain, while scientificantirealists deny, that it is a compelling rule of inference. It seems that anyattempt to settle this debate empirically must beg the question against theantirealist. The present paper argues that this impression is misleading. A methodis described that, by combining Glymour's theory of bootstrapping and Hacking'sarguments from microscopy, allows us to test IBE without begging any antirealistissues.

How does the modern scientific conception of time constrain the project of assigning the mind its proper place in nature? On the scientific conception, it makes no sense to speak of the duration of a pain, or the simultaneity of sensations occurring in different parts of the brain. Such considerations led Henri Poincaré, one of the founders of the modern conception, to conclude that consciousness does not exist in spacetime, but serves as the basic material out of which we must (...) create the physical world. The central claim of Sensorama is that Poincaré was substantially correct. The best way to reconcile the scientific conception of time with the evidence of introspection is through a phenomenalist metaphysic according to which consciousness exists in neither time nor space, but serves as a basis for the logical construction of spacetime and its contents. (shrink)