Results for 'Cancer'

55 found
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  1.  78
    Evidence Amalgamation, Plausibility, and Cancer Research.Marta Bertolaso & Fabio Sterpetti - 2019 - Synthese 196 (8):3279-3317.
    Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We (...)
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  2. Cancer Cells and Adaptive Explanations.Pierre-Luc Germain - 2012 - Biology and Philosophy 27 (6):785-810.
    The aim of this paper is to assess the relevance of somatic evolution by natural selection to our understanding of cancer development. I do so in two steps. In the first part of the paper, I ask to what extent cancer cells meet the formal requirements for evolution by natural selection, relying on Godfrey-Smith’s (2009) framework of Darwinian populations. I argue that although they meet the minimal requirements for natural selection, cancer cells are not paradigmatic Darwinian populations. (...)
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  3. Making Sense of Downward Causation in Manipulationism (with Illustrations From Cancer Research).Christophe Malaterre - 2011 - History and Philosophy of the Life Sciences (33):537-562.
    Many researchers consider cancer to have molecular causes, namely mutated genes that result in abnormal cell proliferation (e.g. Weinberg 1998). For others, the causes of cancer are to be found not at the molecular level but at the tissue level where carcinogenesis consists of disrupted tissue organization with downward causation effects on cells and cellular components (e.g. Sonnenschein and Soto 2008). In this contribution, I ponder how to make sense of such downward causation claims. Adopting a manipulationist account (...)
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  4.  16
    Breast Cancer Knowledge Based System.Suheir H. Almurshidi & Samy S. Abu-Naser - 2018 - International Journal of Academic Health and Medical Research (IJAHMR) 2 (12):7-22.
    The Knowledge Based System for Diagnosing Breast Cancer is used to assist medical students to improve their education on diagnosis and counseling the process of analyzing the biopsy image of the microscope, determining the type of tumor and the treatment method for each case and identifying the disease related questions. According to the Ministry of Health in its annual report in Gaza, between 2009 and 2014 there are 7069 cases of breast cancer, and in 2014 there are 1502 (...)
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  5. Older Adults and Forgoing Cancer Screening.Alexia M. Torke, Peter H. Schwartz, Laura R. Holtz, Kianna Montz & Greg A. Sachs - 2013 - Journal of the American Medical Association Internal Medicine 173 (7):526-531.
    Although there is a growing recognition that older adults and those with extensive comorbid conditions undergo cancer screening too frequently, there is little information about patients’ perceptions regarding cessation of cancer screening. Information on older adults’ views of screening cessation would be helpful both for clinicians and for those designing interventions to reduce overscreening.
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  6.  61
    Applications of the ACGT Master Ontology on Cancer.Mathias Brochhausen, Gabriele Weiler, Luis Martín, Cristian Cocos, Holger Stenzhorn, Norbert Graf, Martin Dörr, Manolis Tsiknakis & Barry Smith - 2008 - In R. Meersman & P. Herrero (eds.), Proceedings of 4th International IFIP Workshop On Semantic Web and Web Semantics (OTM 2008: Workshops), LNCS 5333. pp. 1046–1055.
    In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data. The development of a new ontology was necessary due to problems with existing biomedical ontologies in oncology. The ACGT MO is a test case for the application of best practices in ontology development. This paper provides an overview of the application of the ontology within (...)
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  7. Diagnosing Breast Cancer Using Expert System.Suheir H. Almurshidi - 2018 - Dissertation, Al-Azhar University, Gaza
    The “Expert System for Diagnosing Breast Cancer" is used to assist medical students to improve their education on diagnosis and counseling the process of analyzing the biopsy image of the microscope, determining the type of tumor and the treatment method for each case and identifying the disease related questions. According to the Ministry of Health in its annual report in Gaza, between 2009 and 2014 there are 7069 cases of breast cancer, and in 2014 there are 1502 cases (...)
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  8.  11
    Ethical Issues in Pre-Cancer Testing: The Parallel with Huntington's Disease.Donna L. Dickenson - 2002 - In Bill Fulford, Donna Dickenson & Thomas Murray Murray (eds.), Healthcare Ethics and Human Values: An Introductory Text with Readings and Case Studies. Oxford: Blackwell. pp. 97-100.
    This chapter considers ethical issues involved in genetic testing and screening for susceptibility to various forms of cancer.
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  9.  94
    Fact/Value Holism, Feminist Philosophy, and Nazi Cancer Research.Sharyn Clough - 2015 - Feminist Philosophy Quarterly 1 (1):1-12.
    Fact/value holism has become commonplace in philosophy of science, especially in feminist literature. However, that facts are bearers of empirical content, while values are not, remains a firmly-held distinction. I support a more thorough-going holism: both facts and values can function as empirical claims, related in a seamless, semantic web. I address a counterexample from Kourany where facts and values seem importantly discontinuous, namely, the simultaneous support by the Nazis of scientifically sound cancer research and morally unsound political policies. (...)
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  10.  83
    Towards a Morphogenetic Perspective on Cancer.Armando Aranda-Anzaldo - 2002 - Rivista di Biologia/Biology Forum 95:35-62.
    The purpose of this paper is to present a critique of the current view that reduces cancer to a cellular problem caused by specific gene mutations and to propose, instead, that such a problem might become more intelligible, if it is understood as a phenomenon that results from the breakdown of the morphological plan or Gestalt of the organism. Such and organism, in Aristotelian terms, is characterized for presenting a specific morphe or logos (form) and for having a telos (...)
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  11. From Deputy to "Reichsbevollmächtiger" and Defendant at the Nuremberg Medical Trials : Dr. Kurt Blome and Cancer Research in National Socialist Germany.Gabriele Moser - 2006 - In Wolfgang Uwe Eckart (ed.), Man, Medicine, and the State: The Human Body As an Object of Government Sponsored Medical Research in the 20th Century. Steiner.
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  12. Breast Kanser, Seksuwalidad, at Pagbalikwas.Mark Anthony Dacela & Rachel Joy Martinez Rodriquez - 2015 - Malay 27 (2):118-132.
    Iniaalok ng pag-aaral na ito ang isang panunuring Foucauldian sa pangkasariang karanasan ng babaeng may breast cancer (BRCA). Inihahain din ng mga may-akda ang mga sumusunod na tanong: Paano naaapi ang babaeng may BRCA? Paano hinahamon ng kanyang karanasan ang konsepto ng seksuwalidad? Maaari bang ituring ang kanyang karanasan bilang anyo ng pagbalikwas? Tutugunan ng mga may-akda ang naturang mga tanong gamit ang kapangyarihan-diskurso-seksuwalidad ni Foucault habang ipinapalagay na: (1) matagumpay na naipapakita ng talaangkanan ng seksuwalidad ni Foucault kung (...)
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  13. Two Dogmas of Biology.Leonore Fleming - 2017 - Philosophy, Theory, and Practice in Biology 9 (2).
    The problem with reductionism in biology is not the reduction, but the implicit attitude of determinism that usually accompanies it. Methodological reductionism is supported by deterministic beliefs, but making such a connection is problematic when it is based on an idea of determinism as fixed predictability. Conflating determinism with predictability gives rise to inaccurate models that overlook the dynamic complexity of our world, as well as ignore our epistemic limitations when we try to model it. Furthermore, the assumption of a (...)
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  14. Working for the Cure: Challenging Pink Ribbon Activism [Book Chapter].Maya J. Goldenberg - 2010 - In Roma Harris, Nadine Wathen & Sally Wyatt (eds.), [Book] Configuring Health Consumers: Health Work and the Imperative of Personal Responsibility. Eds. R. Harris, N. Wathen, S. Wyatt. Amsterdam: Palgrave Macmillan, 2010. Palgrave-Macmillan.
    In accordance with the critical women’s health literature recounting the ways that women are encouraged to submit themselves to various sorts of health “imperatives”, I investigate the messages tacitly conveyed to women in “campaigns for the cure” and breast cancer awareness efforts, which, I argue, overemphasizes a “positive attitude”, healthy lifestyle, and cure rather than prevention of this life-threatening disease. I challenge that the message of hope pervading breast cancer discourse silences the despair felt by many women, furthers (...)
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  15.  96
    Patient Understanding of Benefits, Risks, and Alternatives to Screening Colonoscopy.Peter H. Schwartz, Elizabeth Edenberg, Patrick R. Barrett, Susan M. Perkins, Eric M. Meslin & Thomas F. Imperiale - 2013 - Family Medicine 45 (2):83-89.
    While several tests and strategies are recommended for colorectal cancer (CRC) screening, studies suggest that primary care providers often recommend colonoscopy without providing information about its risks or alternatives. These observations raise concerns about the quality of informed consent for screening colonoscopy.
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  16.  88
    Developing the Quantitative Histopathology Image Ontology : A Case Study Using the Hot Spot Detection Problem.Metin Gurcan, Tomaszewski N., Overton John, A. James, Scott Doyle, Alan Ruttenberg & Barry Smith - 2017 - Journal of Biomedical Informatics 66:129-135.
    Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data. To foster organized, cross-disciplinary, information-driven collaborations in the pathological imaging field, we propose to develop an ontology to represent imaging data and methods used in pathological imaging and analysis, and call it Quantitative Histopathological Imaging Ontology – QHIO. We apply QHIO to breast cancer hot-spot detection (...)
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  17. Establishing and Harmonizing Ontologies in an Interdisciplinary Health Care and Clinical Research Environment.Barry Smith & Mathias Brochhausen - 2008 - Studies in Health, Technology and Informatics 134:219-234.
    Ontologies are being ever more commonly used in biomedical informatics and we provide a survey of some of these uses, and of the relations between ontologies and other terminology resources. In order for ontologies to become truly useful, two objectives must be met. First, ways must be found for the transparent evaluation of ontologies. Second, existing ontologies need to be harmonised. We argue that one key foundation for both ontology evaluation and harmonisation is the adoption of a realist paradigm in (...)
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  18.  12
    A Scientific and Socioecononic Review of Betel Nut Use in Taiwan with Bioethical Reflections.Joseph Tham, Geoffrey Sem, Eugene Sit & Michael Cheng-tek Tai - 2017 - Asian Bioethics Review 9 (4):401-414.
    This article addresses the ethics of betel nut use in Taiwan. It first presents scientific facts about the betel quid and its consumption and the generally accepted negative health consequences associated with its use: oral and esophageal cancer, coronary artery disease, metabolic diseases, and adverse effects in pregnancy. It then analyzes the cultural background and economic factors contributing to its popularity in Asia. The governmental and institutional attempts to curb betel nut cultivation, distribution, and sales are also described. Finally, (...)
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  19.  31
    An Ontology for Carcinoma Classification for Clinical Bioinformatics.Anand Kumar, Yum Lina Yip, Barry Smith, Dirk Marwede & Daniel Novotny - 2005 - Studies in Health Technology and Informatics 116 (1):635-640.
    There are a number of existing classifications and staging schemes for carcinomas, one of the most frequently used being the TNM classification. Such classifications represent classes of entities which exist at various anatomical levels of granularity. We argue that in order to apply such representations to the Electronic Health Records one needs sound ontologies which take into consideration the diversity of the domains which are involved in clinical bioinformatics. Here we outline a formal theory for addressing these issues in a (...)
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  20.  68
    Revamping Molecular Biology for the Twentieth First Century, or Putting Back the Theoretical Horse Ahead of the Technological Cart.Armando Aranda-Anzaldo - 2010 - Ludus Vitalis 18 (33):267-270.
    Molecular biology is a relatively new and very successful branch of science but currently it faces challenges posed by very complex issues that cannot be addressed by a traditional reductionist approach. However, despite its origins in the providential shift of some theoretical physicists to biology, currently molecular biology is immersed in a blind trend in which high-throughput technology, able to generate trillions of data, is becoming the leading edge of a discipline that has traded rational and critical thinking for computer (...)
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  21.  18
    On the Proper Treatment of Pathologies in Biomedical Ontologies.Barry Smith & Anand Kumar - 2005 - In Proceedings of the Bio-Ontologies Workshop, Intelligent Systems for Molecular Biology (ISMB 2005). Detroit: pp. 22-23.
    In previous work on biomedical ontologies we showed how the provision of formal definitions for relations such as is_a and part_of can support new types of auto-mated reasoning about biomedical phenomena. We here extend this approach to the transformation_of characteristic of pathologies.
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  22. Review of Julia Kristeva's Hatred and Forgiveness. [REVIEW]Subhasis Chattopadhyay - 2016 - Prabuddha Bharata or Awakened India 121 (10):721-22.
    Julia Kristeva shines in this book. The review makes a case for us studying Kristeva as the most relevant psychoanalyst of our time. She should be read over Lacan. Her understanding of this century is more incisive than any other psychoanalytic thinker alive today. At least, in this book. Kristeva's contention is that hatred gives way to paranoia.
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  23. The Problem of Abortion and the Doctrine of Double Effect.Philippa Foot - 1967 - Oxford Review 5:5-15.
    One of the reasons why most of us feel puzzled about the problem of abortion is that we want, and do not want, to allow to the unborn child the rights that belong to adults and children. When we think of a baby about to be born it seems absurd to think that the next few minutes or even hours could make so radical a difference to its status; yet as we go back in the life of the fetus we (...)
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  24. Decide As You Would With Full Information! An Argument Against Ex Ante Pareto.Marc Fleurbaey & Alex Voorhoeve - 2013 - In Ole Norheim, Samia Hurst, Nir Eyal & Dan Wikler (eds.), Inequalities in Health: Concepts, Measures, and Ethics. Oxford University Press.
    Policy-makers must sometimes choose between an alternative which has somewhat lower expected value for each person, but which will substantially improve the outcomes of the worst off, or an alternative which has somewhat higher expected value for each person, but which will leave those who end up worst off substantially less well off. The popular ex ante Pareto principle requires the choice of the alternative with higher expected utility for each. We argue that ex ante Pareto ought to be rejected (...)
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  25. Natality and Mortality: Rethinking Death with Cavarero.Alison Stone - 2010 - Continental Philosophy Review 43 (3):353-372.
    In this article I rethink death and mortality on the basis of birth and natality, drawing on the work of the Italian feminist philosopher Adriana Cavarero. She understands birth to be the corporeal event whereby a unique person emerges from the mother’s body into the common world. On this basis Cavarero reconceives death as consisting in bodily dissolution and re-integration into cosmic life. This impersonal conception of death coheres badly with her view that birth is never exclusively material but always (...)
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  26.  32
    Developing an Expert System for Papaya Plant Disease Diagnosis.Mohammed M. Abu-Saqer & Samy S. Abu-Naser - 2019 - International Journal of Academic Engineering Research (IJAER) 3 (4):14-21.
    The papaya is a plant that grows in tropical climates and also known as pawpaws or papaws, it has many health benefits like reducing risk of heart disease, diabetes, cancer, aiding in digestion, improving blood glucose control in people with diabetes, lowering blood pressure, and improving wound healing. With these big health benefits and with taken into consideration that it’s available at most times of the year. The farmers have to take care of this plant. Because of that we (...)
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  27. Not Always Worth the Effort: Difficulty and the Value of Achievement.Sukaina Hirji - 2019 - Pacific Philosophical Quarterly 100 (2):525-548.
    Recent literature has argued that what makes certain activities ranging from curing cancer to running a marathon count as achievements, and what makes achievements intrinsically valuable is, centrally, that they involve great effort. Although there is much the difficulty-based view gets right, I argue that it generates the wrong results about some central cases of achievement, and this is because it is too narrowly focused on only one perfectionist capacity, the will. I propose a revised perfectionist account on which (...)
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  28. A Theory of Evidence for Evidence-Based Policy.Nancy Cartwright & Jacob Stegenga - 2011 - In Philip Dawid, William Twining & Mimi Vasilaki (eds.), Evidence, Inference and Enquiry. Oup/British Academy. pp. 291.
    WE AIM HERE to outline a theory of evidence for use. More specifically we lay foundations for a guide for the use of evidence in predicting policy effectiveness in situ, a more comprehensive guide than current standard offerings, such as the Maryland rules in criminology, the weight of evidence scheme of the International Agency for Research on Cancer (IARC), or the US ‘What Works Clearinghouse’. The guide itself is meant to be well-grounded but at the same time to give (...)
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  29. Causality in Medicine with Particular Reference to the Viral Causation of Cancers.Brendan Clarke - 2011 - Dissertation, University College London
    In this thesis, I give a metascientific account of causality in medicine. I begin with two historical cases of causal discovery. These are the discovery of the causation of Burkitt’s lymphoma by the Epstein-Barr virus, and of the various viral causes suggested for cervical cancer. These historical cases then support a philosophical discussion of causality in medicine. This begins with an introduction to the Russo- Williamson thesis (RWT), and discussion of a range of counter-arguments against it. Despite these, I (...)
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  30. Introducción al problema de la continuidad del tratamiento beneficioso para los sujetos de investigación.Ignacio Mastroleo - 2015 - In Jorge Alberto Álvarez Díaz (ed.), Ensayos sobre ética de la salud. Ciudad de México: Universidad Autónoma Metropolitana - Unidad Xochimilco. pp. 67 - 99.
    ¿Qué ocurre con la continuidad del tratamiento de los sujetos de investigación después de que realizan la última visita del ensayo en el que participan? En algunos casos, la falta de continuidad de atención de la salud apropiada podría poner en peligro la salud de estas personas. Por lo tanto, es probable que los sujetos de investigación que al terminar su participación en un ensayo todavía se encuentran enfermos, necesiten continuar con el tratamiento en estudio u otra atención de la (...)
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  31. Explanatoriness and Evidence: A Reply to McCain and Poston.William Roche & Elliott Sober - 2014 - Thought: A Journal of Philosophy 3 (3):193-199.
    We argue elsewhere that explanatoriness is evidentially irrelevant . Let H be some hypothesis, O some observation, and E the proposition that H would explain O if H and O were true. Then O screens-off E from H: Pr = Pr. This thesis, hereafter “SOT” , is defended by appeal to a representative case. The case concerns smoking and lung cancer. McCain and Poston grant that SOT holds in cases, like our case concerning smoking and lung cancer, that (...)
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  32. Rationalization as Performative Pretense.Jason D'Cruz - 2015 - Philosophical Psychology 28 (7):980-1000.
    Rationalization in the sense of biased self-justification is very familiar. It's not cheating because everyone else is doing it too. I didn't report the abuse because it wasn't my place. I understated my income this year because I paid too much in tax last year. I'm only a social smoker, so I won't get cancer. The mental mechanisms subserving rationalization have been studied closely by psychologists. However, when viewed against the backdrop of philosophical accounts of the regulative role of (...)
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  33. Understanding, Communication, and Consent.Joseph Millum & Danielle Bromwich - 2018 - Ergo: An Open Access Journal of Philosophy 5:45-68.
    Misconceived Consent: Miguel has stage IV lung cancer. He has nearly exhausted his treatment options when his oncologist, Dr. Llewellyn, tells him about an experimental vaccine trial that may boost his immune response to kill cancer cells. Dr. Llewellyn provides Miguel with a consent form that explains why the study is being conducted, what procedures he will undergo, what the various risks and benefits are, alternative sources of treatment, and so forth. She even sits down with him, carefully (...)
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  34. ANTICORRUPTION NATIONAL SYSTEM: Model Whistleblowers Direct Citizen Action Against Corruption in Mexico.Carlos Medel-Ramírez - 2018 - Social Science Research Network:1-12.
    The phenomenon of corruption is a cancer that affects our country and that it is necessary to eradicate; This dilutes the opportunities for economic and social development, privileging the single conjunction of particular interests, political actors in non-legal agreements for their own benefit, which lead to acts of corruption. Recent studies indicate that the level of corruption present in a political system is directly related to the type of institutional structure that defines it (Boehm and Lambsdorff, 2009), as well (...)
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  35. Transoral Laser Surgery for Laryngeal Carcinoma: Has Steiner Achieved a Genuine Paradigm Shift in Oncological Surgery?A. T. Harris, Attila Tanyi, R. D. Hart, J. Trites, M. H. Rigby, J. Lancaster, A. Nicolaides & S. M. Taylor - 2018 - Annals of the Royal College of Surgeons of England 100 (1):2-5.
    Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single modality treatment of choice in early laryngeal cancers (T1 and T2) and occasionally in the more advanced forms of the disease (T3 and T4), predomi- nantly within the supraglottis. Thomas Kuhn, the American physicist turned philosopher and historian of science, coined the phrase ‘paradigm shift’ in (...)
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  36.  67
    The Ethics of Making Risky Decisions for Others.Luc Bovens - 2019 - In Mark D. White (ed.), Oxford Handbook of Ethics and Economics. Oxford University Press. pp. 446-473.
    Utilitarianism, it has been said, is not sensitive to the distribution of welfare. In making risky decisions for others there are multiple sensitivities at work. I present examples of risky decision-making involving drug allocations, charitable giving, breast-cancer screening and C-sections. In each of these examples there is a different sensitivity at work that pulls away from the utilitarian prescription. Instances of saving fewer people at a greater risk to many is more complex because there are two distributional sensitivities at (...)
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  37. Small Tumors as Risk Factors Not Disease.Peter H. Schwartz - 2014 - Philosophy of Science 81 (5):986-998.
    I argue that ductal carcinoma in situ (DCIS), the tumor most commonly diagnosed by breast mammography, cannot be confidently classified as cancer, that is, as pathological. This is because there may not be dysfunction present in DCIS—as I argue based on its high prevalence and the small amount of risk it conveys—and thus DCIS may not count as a disease by dysfunction-requiring approaches, such as Boorse’s biostatistical theory and Wakefield’s harmful dysfunction account. Patients should decide about treatment for DCIS (...)
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  38.  46
    How Do Medical Researchers Make Causal Inferences?Olaf Dammann, Ted Poston & Paul Thagard - forthcoming - In What is scientific knowledge? An introduction to contemporary epistemology of science. London, UK:
    Bradford Hill (1965) highlighted nine aspects of the complex evidential situation a medical researcher faces when determining whether a causal relation exists between a disease and various conditions associated with it. These aspects are widely cited in the literature on epidemiological inference as justifying an inference to a causal claim, but the epistemological basis of the Hill aspects is not understood. We offer an explanatory coherentist interpretation, explicated by Thagard's ECHO model of explanatory coherence. The ECHO model captures the complexity (...)
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  39.  57
    Oncology Ontology in the NCI Thesaurus.Anand Kumar & Barry Smith - 2005 - Artificial Intelligence in Medicine:213-220.
    The National Cancer Institute’s Thesaurus (NCIT) has been created with the goal of providing a controlled vocabulary which can be used by specialists in the various sub-domains of oncology. It is intended to be used for purposes of annotation in ways designed to ensure the integration of data and information deriving from these various sub-domains, and thus to support more powerful cross-domain inferences. In order to evaluate its suitability for this purpose, we examined the NCIT’s treatment of the kinds (...)
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  40.  44
    Exercise Prescription and The Doctor's Duty of Non-Maleficence.Jonathan Pugh, Christopher Pugh & Julian Savulesu - 2017 - British Journal of Sports Medicine 51 (21):1555-1556.
    An abundance of data unequivocally shows that exercise can be an effective tool in the fight against obesity and its associated co-morbidities. Indeed, physical activity can be more effective than widely-used pharmaceutical interventions. Whilst metformin reduces the incidence of diabetes by 31% (as compared with a placebo) in both men and women across different racial and ethnic groups, lifestyle intervention (including exercise) reduces the incidence by 58%. In this context, it is notable that a group of prominent medics and exercise (...)
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  41. Is Explanatoriness a Guide to Confirmation? A Reply to Climenhaga.William Roche & Elliott Sober - 2017 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 48 (4):581-590.
    We argued that explanatoriness is evidentially irrelevant in the following sense: Let H be a hypothesis, O an observation, and E the proposition that H would explain O if H and O were true. Then our claim is that Pr = Pr. We defended this screening-off thesis by discussing an example concerning smoking and cancer. Climenhaga argues that SOT is mistaken because it delivers the wrong verdict about a slightly different smoking-and-cancer case. He also considers a variant of (...)
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  42.  66
    Can Government Regulate Technology?Edmund Byrne - 1983 - In Philosophy and Technology, Boston Studies in the Philosophy of Science, vol. 80. Dordrecht: pp. 17-33.
    Theorists and activists favor empowering government agencies to regulate technology; but an examination of such regulation by the US government exposes the inadequacy of any such regimen. Vested interests routinely interfere, e.g., keeping administration of polio vaccine in the hands of physicians, political infighting with regard to cancer research funding, advantages gained from noncompliance with military technology-constraining treaties. Public/private salary differences limit availability of the best talents for government positions, nor are truly appropriate regulatory policies easily arrived at in (...)
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  43.  57
    Bioinformatics Advances in Saliva Diagnostics.Ji-Ye Ai, Barry Smith & David T. W. Wong - 2012 - International Journal of Oral Science 4 (2):85--87.
    There is a need recognized by the National Institute of Dental & Craniofacial Research and the National Cancer Institute to advance basic, translational and clinical saliva research. The goal of the Salivaomics Knowledge Base (SKB) is to create a data management system and web resource constructed to support human salivaomics research. To maximize the utility of the SKB for retrieval, integration and analysis of data, we have developed the Saliva Ontology and SDxMart. This article reviews the informatics advances in (...)
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  44. Causation in Medicine.Brendan Clarke - 2012 - In Wenceslao J. Gonzalez (ed.), Conceptual Revolutions: from Cognitive Science to Medicine. Netbiblo.
    In this paper, I offer one example of conceptual change. Specifically, I contend that the discovery that viruses could cause cancer represents an excellent example of branch jumping, one of Thagard’s nine forms of conceptual change. Prior to about 1960, cancer was generally regarded as a degenerative, chronic, non-infectious disease. Cancer causation was therefore usually held to be a gradual process of accumulating cellular damage, caused by relatively non-specific component causes, acting over long periods of time. Viral (...)
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  45.  38
    REVIEW OF MUSIC AND ITS THERAPEUTICS W.S.R. AYURVEDIC CLASSICS (BRIHATRAYEE.Dr Devanand Upadhyay - 2016 - Indian Journal of Agriculture and Allied Sciences 2 (1):114-118.
    Ayurveda is the science of living being. With the aim of health and procurement of disease it almost covers all facets of life. It includes health of an individual at physical, mental, spiritual, social level. Ayurvedic classics includes brihatrayee samhita like Charak, Sushruta and Ashtanga Hridaya. A review based study of music (geet, sangeet) was done in these classics to explore whether these classics includes any form of music as therapy or not. Based on review of these classics it was (...)
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  46.  89
    Pornography Embodied: Joan Mason-Grant Remembered (1958–2009).Alison Wylie - 2011 - Hypatia 26 (1):130-131.
    When the cluster on “Sexual Expressions” began to take shape, one of the first people I thought of to serve as a referee was Joan Mason-Grant, given her longstanding philosophical and activist interest in pornography. It was with great sorrow that I learned, when I contacted her, that she had been diagnosed with a fast moving cancer. Joan was most interested to hear about this emerging “found cluster”; “it sounds like an interesting issue of Hypatia to look forward to, (...)
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  47. La obligación de continuidad de tratamiento beneficioso hacia los sujetos de investigación.Ignacio Mastroleo - 2012 - Dissertation, Universidad de Buenos Aires
    Todos los días se prueban nuevos psicofármacos, tratamientos para el VIH/SIDA o el cáncer, entre otras enfermedades. Algunos de esos tratamientos son lo suficientemente exitosos como para cronificar enfermedades antes consideradas mortales, como los antirretrovirales para el VIH/SIDA o el imatinib para la leucemia mieloide a principios del 2000. No obstante, antes de que puedan ser comercializados o estar disponibles en los sistemas de salud pública, deben pasar por una serie de rigurosas pruebas de calidad, seguridad y eficacia. Estas pruebas (...)
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  48.  50
    Sistema Nacional Anticorrupción: Whistleblowers O El Poder De Acción Ciudadana Directa En El Combate a La Corrupción En México.Carlos Medel-Ramírez (ed.) - 2016 - España: Editorial Eumed – España.
    El fenómeno de la corrupción es un cáncer que afecta a nuestro país y que es necesario erradicar; éste diluye las oportunidades de desarrollo económico y social, privilegiando la sola conjunción de intereses particulares, de actores políticos en acuerdos no legales en beneficio propio, los cuales derivan en actos de corrupción. Estudios recientes señalan que el nivel de corrupción presente en un sistema político está directamente relacionado con el tipo de estructura institucional que lo defina (Boehm y Lambsdorff, 2009), así (...)
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  49.  16
    Evolution and Ethics of Eugenics.Nicolae Sfetcu - manuscript
    As eugenics is defined, it is very difficult to make a clear distinction between science (medicine, genetic engineering) and eugenics as a included field. And to set a line over which genetic engineering should not go further, according to moral, legal and religious norms. If we accept the help of genetics in finding ways to fight cancer, diabetes, or HIV, we also accept positive eugenics as they are defined now. And if we accept genetic screening, and interventions on the (...)
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  50.  38
    Eugénisme.Nicolae Sfetcu - manuscript
    Dans la définition de l'eugénisme, il est très difficile d'établir une distinction claire entre la science (médecine, génie génétique) et l'eugénisme. Et de définir une ligne de conduite sur laquelle l'ingénierie génétique ne devrait pas aller, conformément aux normes morales, juridiques et religieuses. Tant que nous acceptons l'aide de la génétique pour trouver des moyens de lutter contre le cancer, le diabète ou le VIH, nous acceptons également l'eugénisme positif tel qu'il est actuellement. Et tant que nous acceptons le (...)
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