Results for 'Gene Concepts'

961 found
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  1. Alternative Splicing, the Gene Concept, and Evolution.Stephen Downes - 2004 - History and Philosophy of the Life Sciences 26 (1):91 - 104.
    Alternative splicing allows for the production of many gene products from a single coding sequence. I introduce the concept of alternative splicing via some examples. I then discuss some current hypotheses about the explanatory role of alternative splicing, including the claim that splicing is a significant contributor to the difference in complexity between the human genome and proteosome. Hypotheses such as these bring into question our working concepts of the gene. I examine several gene concepts (...)
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  2. The Idea of a Social Cycle.Gene Callahan & Andreas Hoffman - manuscript
    The paper aims to explore what it means for something to be a social cycle, for a theory to be a social cycle theory, and to offer a suggestion for a simple, yet, we believe, fundamentally grounded schema for categorizing them. We show that a broad range of cycle theories can be described within the concept of disruption and adjustments. Further, many important cycle theories are true endogenous social cycle theories in which the theory provides a reason why the cycle (...)
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  3. Looking beyond gene concepts[REVIEW]Alan C. Love - 2006 - Philosophy of Science 73 (2):247–250.
    Book Review: What Genes Can’t Do By Lenny Moss .
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  4. Gene Mobility and the Concept of Relatedness.Jonathan Birch - 2014 - Biology and Philosophy 29 (4):445-476.
    Cooperation is rife in the microbial world, yet our best current theories of the evolution of cooperation were developed with multicellular animals in mind. Hamilton’s theory of inclusive fitness is an important case in point: applying the theory in a microbial setting is far from straightforward, as social evolution in microbes has a number of distinctive features that the theory was never intended to capture. In this article, I focus on the conceptual challenges posed by the project of extending Hamilton’s (...)
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  5. Genes and Virtue: Exploring how heritability beliefs shape conceptions of virtue and its development.Matt Stichter, Matthew Vess, Rebecca Brooker & Jenae Nederhiser - 2019 - Behavioral Genetics 49 (2):168-174.
    In this paper, we provide an overview of our ongoing project in the Genetics and Human Agency Initiative sponsored by the John Templeton Foundation. Our project focuses on the ways that lay beliefs about the heritability of virtue influence reasoning about the nature of virtue, parenting behaviors, and the development of virtue in children. First, we provide philosophical perspectives on the nature of virtue and suggest that viewing virtue as a malleable skill may have important advantages. Next, we review theory (...)
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  6. Re-examining the Gene in Personalized Genomics.Jordan Bartol - 2013 - Science & Education 22 (10):2529-2546.
    Personalized genomics companies (PG; also called ‘direct-to-consumer genetics’) are businesses marketing genetic testing to consumers over the Internet. While much has been written about these new businesses, little attention has been given to their roles in science communication. This paper provides an analysis of the gene concept presented to customers and the relation between the information given and the science behind PG. Two quite different gene concepts are present in company rhetoric, but only one features in the (...)
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  7. Genes `for' phenotypes: A modern history view.Jonathan Michael Kaplan & Massimo Pigliucci - 2001 - Biology and Philosophy 16 (2):189--213.
    We attempt to improve the understanding of the notion of agene being `for a phenotypic trait or traits. Considering theimplicit functional ascription of one thing being `for another,we submit a more restrictive version of `gene for talk.Accordingly, genes are only to be thought of as being forphenotypic traits when good evidence is available that thepresence or prevalence of the gene in a population is the resultof natural selection on that particular trait, and that theassociation between that trait and (...)
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  8. Genes and organisms in the legacy of the modern synthesis.J. Arvid Ågren - 2023 - In T. E. Dickins & B. J. Dickins (eds.), Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory. Springer. pp. 555–568.
    The gene's-eye view of evolution is an influential but contentious perspective on biology. It emerged in the aftermath of the Modern Synthesis and both proponents and detractors have stressed the link between the two. In particular, both the Modern Synthesis and the gene's-eye view have been criticized for overemphasizing the role genes at the expense of organisms in evolutionary explanations. In this chapter, I discuss the connection between the Modern Synthesis and the gene’s-eye view and evaluate the (...)
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  9. Cohesion, Gene flow, and the Nature of Species.Matthew J. Barker & Robert A. Wilson - 2010 - Journal of Philosophy 107 (2):59-77.
    A far-reaching and influential view in evolutionary biology claims that species are cohesive units held together by gene flow. Biologists have recognized empirical problems facing this view; after sharpening the expression of the view, we present novel conceptual problems for it. At the heart of these problems is a distinction between two importantly different concepts of cohesion, what we call integrative and response cohesion. Acknowledging the distinction problematizes both the explanandum of species cohesion and the explanans of (...) flow that are central to the view we discuss. We conclude by tracing four broader implications for the study and conceptualization of species. (shrink)
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  10. Genes, Causation and Intentionality.Marcel Weber - 2005 - History and Philosophy of the Life Sciences 27 (3/4):399-411.
    I want to exhibit the deeper metaphysical reasons why some common ways of describing the causal role of genes in development and evolution are problematic. Specifically, I show why using the concept of information in an intentional sense in genetics is inappropriate, even given a naturalistic account of intentionality. Furthermore, I argue that descriptions that use notions such as programming, directing or orchestrating are problematic not for empirical reasons, but because they are not strictly causal. They are intentional. By contrast, (...)
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  11. Gene Editing, the Mystic Threat to Human Dignity.Vera Lúcia Raposo - 2019 - Journal of Bioethical Inquiry 16 (2):249-257.
    Many arguments have been made against gene editing. This paper addresses the commonly invoked argument that gene editing violates human dignity and is ultimately a subversion of human nature. There are several drawbacks to this argument. Above all, the concept of what human dignity means is unclear. It is not possible to condemn a practice that violates human dignity if we do not know exactly what is being violated. The argument’s entire reasoning is thus undermined. Analyses of the (...)
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  12. (1 other version)The gene as the unit of selection: a case of evolutive delusion.Armando Aranda-Anzaldo - 1997 - Ludus Vitalis 5 (9):91-120.
    The unit of selection is the concept of that ‘something’ to which biologists refer when they speak of an adaptation as being ‘for the good of’ something. Darwin identified the organism as the unit of selection because for him the ‘struggle for existence’ was an issue among individuals. Later on it was suggested that, in order to understand the evolution of social behavior, it is necessary to argue that groups, and not individuals, are the units of selection. The last addition (...)
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  13. Why the Gene will not return.Elisabeth A. Lloyd - 2005 - Philosophy of Science 72 (2):287-310.
    I argue that four of the fundamental claims of those calling themselves `genic pluralists'Philip Kitcher, Kim Sterelny, and Ken Watersare defective. First, they claim that once genic selectionism is recognized, the units of selection problems will be dissolved. Second, Sterelny and Kitcher claim that there are no targets of selection. Third, Sterelny, Kitcher, and Waters claim that they have a concept of genic causation that allows them to give independent genic causal accounts of all selection processes. I argue that each (...)
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  14. Driven to extinction? The ethics of eradicating mosquitoes with gene-drive technologies.Jonathan Pugh - 2016 - Journal of Medical Ethics 42 (9):578-581.
    Mosquito-borne diseases represent a significant global disease burden, and recent outbreaks of such diseases have led to calls to reduce mosquito populations. Furthermore, advances in ‘gene-drive’ technology have raised the prospect of eradicating certain species of mosquito via genetic modification. This technology has attracted a great deal of media attention, and the idea of using gene-drive technology to eradicate mosquitoes has been met with criticism in the public domain. In this paper, I shall dispel two moral objections that (...)
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  15. Has classical gene position been practically reduced?Oriol Vidal & David Teira - 2020 - Biology and Philosophy 35 (5):1-20.
    One of the defining features of the classical gene was its position. In molecular genetics, positions are defined instead as nucleotide numbers and there is no clear correspondence with its classical counterpart. However, the classical gene position did not simply disappear with the development of the molecular approach, but survived in the lab associated to different genetic practices. The survival of classical gene position would illustrate Waters’ view about the practical persistence of the genetic approach beyond reductionism (...)
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  16. "Life" shaped by genes that depend on their surrounds.Paul Gottlob Layer - 2011 - Annals of the History and Philosophy of Biology 16:153-170.
    Never was dogmatic reductionism helpful in conceiving the phenomenon of life. The post-genomic era has made it clear that genes alone cannot explain the functioning of whole organisms. Already each cell represents a unique, non-recurring individual. Recent progress in developmental biology has conveyed new perspectives both on the makings of individual organisms (ontogeny), as on evolutionary change (Evo-Devo). The genome (the entirety of all genes) of an animal remains constant from fertilization onwards in each cell. The realization of genes requires (...)
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  17. Is It Ethical To Patent Human Genes?Annabelle Lever - 2008 - In Axel Gosseries, Alain Marciano & Alain Strowel (eds.), Intellectual Property and Theories of Justice. Basingstoke & N.Y.: Palgrave McMillan. pp. 246--64.
    This paper examines the claims that moral objections to the patenting of human genes are misplaced and rest on confusions about what a patent is, or what is patented by a human gene patent. It shows that theese objections rest on too simple a conception of property rights, and the connections betwteen familiar moral objections to private property and moral objections to the patenting of human genes. Above all, the paper claims, objections to HGPs often reflect worries about the (...)
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  18. Responsible risking, forethought, and the case of germline gene editing.Madeleine Hayenhjelm - 2023 - In Adriana Placani & Stearns Broadhead (eds.), _Risk and Responsibility in Context_. New York: Routledge. pp. 149-169.
    This chapter addresses a general question: What is responsible risking? It explores the notion of "responsible risking" as a thick moral concept, and it argues that the notion can be given moral content that could be action-guiding and add an important tool to our moral toolbox. To impose risks responsibly, on this view, is to take on responsibility in a good way. A core part of responsible risking, this chapter argues, is some version of a Forethought Condition. Such a condition (...)
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  19. Genotype–phenotype mapping and the end of the ‘genes as blueprint’ metaphor.Massimo Pigliucci - 2010 - Philosophical Transactions Royal Society B 365:557–566.
    In a now classic paper published in 1991, Alberch introduced the concept of genotype–phenotype (G!P) mapping to provide a framework for a more sophisticated discussion of the integration between genetics and developmental biology that was then available. The advent of evo-devo first and of the genomic era later would seem to have superseded talk of transitions in phenotypic space and the like, central to Alberch’s approach. On the contrary, this paper shows that recent empirical and theoretical advances have only sharpened (...)
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  20. Is the Neo-Aristotelian Concept of Organism Presupposed in Biology?Parisa Moosavi - 2020 - In Hähnel Martin (ed.), Aristotelian Naturalism: A Research Companion. Springer.
    According to neo-Aristotelian ethical naturalism, moral goodness is an instance of natural goodness, a kind of normativity supposedly already present in nature in the biological realm of non-human living things. Proponents of this view appeal to Michael Thompson’s conception of a life-form--the form of a living organism--to give an account of natural goodness. However, although neo-Aristotelians call themselves naturalists, they hardly ever consult the science of biology to defend their commitments regarding biological organisms. This has led many critics to argue (...)
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  21. (5 other versions)Ontology (Science).Barry Smith - 2008 - In Carola Eschenbach & Mike Grüninger (eds.), Formal Ontology in Information Systems. Proceedings of the Fifth International Conference (FOIS 2008). Amsterdam: IOS Press. pp. 21-35.
    Increasingly, in data-intensive areas of the life sciences, experimental results are being described in algorithmically useful ways with the help of ontologies. Such ontologies are authored and maintained by scientists to support the retrieval, integration and analysis of their data. The proposition to be defended here is that ontologies of this type – the Gene Ontology (GO) being the most conspicuous example – are a part of science. Initial evidence for the truth of this proposition (which some will find (...)
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  22. Subjective Evolution of Consciousness in Modern Science and Vedāntic Philosophy: Particulate Concept to Quantum Mechanics in Modern Science and Śūnyavāda to Acintya-Bhedābheda-Tattva in Vedānta.PhD Ph D. Shanta - 2019 - In Siddheshwar Rameshwar Bhatt (ed.), Quantum Reality and Theory of Śūnya. Springer.
    How the universe came to be what it is now is a key philosophical question. The hypothesis that it came from nothing or śūnya (as proposed by Stephen Hawking, among others) proves to be dissembling, since the quantum vacuum can hardly be considered a void (śūnya). In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on earth is nothing but a mere increment in the complexity (...)
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  23. Reference, Truth, and Biological Kinds.Marcel Weber - 2014 - In: J. Dutant, D. Fassio and A. Meylan (Eds.) Liber Amicorum Pascal Engel.
    This paper examines causal theories of reference with respect to how plausible an account they give of non-physical natural kind terms such as ‘gene’ as well as of the truth of the associated theoretical claims. I first show that reference fixism for ‘gene’ fails. By this, I mean the claim that the reference of ‘gene’ was stable over longer historical periods, for example, since the classical period of transmission genetics. Second, I show that the theory of partial (...)
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  24. A semiotic analysis of the genetic information.Charbel El-Hani, Joao Queiroz & Claus Emmeche - 2006 - Semiotica - Journal of the International Association for Semiotic Studies / Revue de l'Association Internationale de Sémiotique 1 (4):1-68.
    Terms loaded with informational connotations are often employed to refer to genes and their dynamics. Indeed, genes are usually perceived by biologists as basically ‘the carriers of hereditary information.’ Nevertheless, a number of researchers consider such talk as inadequate and ‘just metaphorical,’ thus expressing a skepticism about the use of the term ‘information’ and its derivatives in biology as a natural science. First, because the meaning of that term in biology is not as precise as it is, for instance, in (...)
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  25. Why Machine-Information Metaphors are Bad for Science and Science Education.Massimo Pigliucci & Maarten Boudry - 2011 - Science & Education 20 (5-6):471.
    Genes are often described by biologists using metaphors derived from computa- tional science: they are thought of as carriers of information, as being the equivalent of ‘‘blueprints’’ for the construction of organisms. Likewise, cells are often characterized as ‘‘factories’’ and organisms themselves become analogous to machines. Accordingly, when the human genome project was initially announced, the promise was that we would soon know how a human being is made, just as we know how to make airplanes and buildings. Impor- tantly, (...)
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  26. Biomedical Ontologies.Barry Smith - 2022 - In Peter L. Elkin (ed.), Terminology, Ontology and Their Implementations: Teaching Guide and Notes. Springer. pp. 125-169.
    We begin at the beginning, with an outline of Aristotle’s views on ontology and with a discussion of the influence of these views on Linnaeus. We move from there to consider the data standardization initiatives launched in the 19th century, and then turn to investigate how the idea of computational ontologies developed in the AI and knowledge representation communities in the closing decades of the 20th century. We show how aspects of this idea, particularly those relating to the use of (...)
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  27. Ontology (science).Barry Smith - 2001 - In Barry Smith & Christopher Welty (eds.), Formal Ontology in Information Systems (FOIS). ACM Press. pp. 21-35.
    Increasingly, in data-intensive areas of the life sciences, experimental results are being described in algorithmically useful ways with the help of ontologies. Such ontologies are authored and maintained by scientists to support the retrieval, integration and analysis of their data. The proposition to be defended here is that ontologies of this type – the Gene Ontology (GO) being the most conspicuous example – are a part of science. Initial evidence for the truth of this proposition (which some will find (...)
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  28. Coherent Causal Control: A New Distinction within Causation.Marcel Weber - 2022 - European Journal for Philosophy of Science 12 (4):69.
    The recent literature on causality has seen the introduction of several distinctions within causality, which are thought to be important for understanding the widespread scientific practice of focusing causal explanations on a subset of the factors that are causally relevant for a phenomenon. Concepts used to draw such distinctions include, among others, stability, specificity, proportionality, or actual-difference making. In this contribution, I propose a new distinction that picks out an explanatorily salient class of causes in biological systems. Some select (...)
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  29. Towards a Multidimensional Metaconception of Species.Catherine Kendig - 2013 - Ratio 27 (2):155-172.
    Species concepts aim to define the species category. Many of these rely on defining species in terms of natural lineages and groupings. A dominant gene-centred metaconception has shaped notions of what constitutes both a natural lineage and a natural grouping. I suggest that relying on this metaconception provides an incomplete understanding of what constitute natural lineages and groupings. If we take seriously the role of epigenetic, behavioural, cultural, and ecological inheritance systems, rather than exclusively genetic inheritance, a broader (...)
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  30. Symmetry-breaking dynamics in development.Noah Moss Brender - 2017 - Phenomenology and the Cognitive Sciences 16 (4):585-596.
    Recognition of the plasticity of development — from gene expression to neuroplasticity — is increasingly undermining the traditional distinction between structure and function, or anatomy and behavior. At the same time, dynamic systems theory — a set of tools and concepts drawn from the physical sciences — has emerged as a way of describing what Maurice Merleau-Ponty calls the “dynamic anatomy” of the living organism. This article surveys and synthesizes dynamic systems models of development from biology, neuroscience, and (...)
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  31. Dawkins and Latour. A Tale of Two Unlikely Fellows.Hajo Greif - 2005 - In Arno Bammé (ed.), Yearbook 2005 of the Institute for Advanced Studies on Science, Technology and Society. Profil. pp. 99-124.
    Two popular, yet highly controversial concepts of non-human agency from two different fields of knowledge are compared in this essay: the theory of the Selfish Gene, introduced into neo-Darwinian evolutionary biology by Richard Dawkins, and Actor-Network Theory, as brought forward in Science & Technology Studies by Bruno Latour. It is argued that the two theories, despite all apparent differences, share key motifs and motivations when they try to forward knowledge in their respective fields by adopting a vocabulary that (...)
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  32. The dialectical method in Xenophon and Antisthenes.Santiago Chame - 2023 - In Claudia Mársico & Daniel Rossi Nunes Lopes (eds.), Xenophon, the Philosopher. Argumentation and Ethics. Peter Lang. pp. 231-248.
    Xenophon’s conception of the dialectical method shares many similarities with Antisthenes’ point of view regarding the relation between language and reality. The key element supporting this reading is the parallel between Xenophon’s method of dialegein kata genē and Antisthenes’ method of episkepsis tōn onomatōn. In this paper, I claim that a correct understanding of both methods yields a clear structural proximity between the two Socratics on the issue of dialectics. Although they present some significant differences, which I will also explore, (...)
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  33. Why some Apes became Humans, Competition, consciousness, and culture.Pouwel Slurink - 2002 - Dissertation, Radboud University
    Chapter 1 (To know in order to survive) & Chapter 2 (A critique of evolved reason) explain human knowledge and its limits from an evolutionary point of view. Chapter 3 (Captured in our Cockpits) explains the evolution of consciousness, using value driven decision theory. Chapter 4-6 (Chapter 4 Sociobiology, Chapter 5 Culture: the Human Arena), Chapter 6, Genes, Memes, and the Environment) show that to understand culture you have at least to deal with 4 levels: genes, brains, the environment, culture. (...)
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  34. Crucial steps to life: From chemical reactions to code using agents.Witzany Guenther - 2016 - Biosystems 140:49-57.
    The concepts of the origin of the genetic code and the definitions of life changed dramatically after the RNA world hypothesis. Main narratives in molecular biology and genetics such as the “central dogma,” “one gene one protein” and “non-coding DNA is junk” were falsified meanwhile. RNA moved from the transition intermediate molecule into centre stage. Additionally the abundance of empirical data concerning nonrandom genetic change operators such as the variety of mobile genetic elements, persistent viruses and defectives do (...)
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  35. Diferenciação e Determinação Sexual dos Animais.Emanuel Isaque Cordeiro da Silva -
    DIFERENCIAÇÃO SEXUAL -/- Emanuel Isaque Cordeiro da Silva Instituto Agronômico de Pernambuco Embrapa Semiárido -/- • _____OBJETIVO -/- Os estudantes de Veterinária e de Zootecnia estão ligados à disciplina Reprodução Animal, um pelos mecanismos fisiológicos para evitar e tratar as possíveis patologias do trato reprodutivo dos animais domésticos, e outro para o entendimento dos processos fisiológicos visando o manejo reprodutivo e a procriação para a formação de um plantel geneticamente melhorado. Sendo assim, a finalidade do presente trabalho é apresentar os (...)
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  36. STABLE ADAPTIVE STRATEGY of HOMO SAPIENS and EVOLUTIONARY RISK of HIGH TECH. Transdisciplinary essay.Valentin Cheshko, Valery Glazko, Gleb Yu Kosovsky & Anna S. Peredyadenko (eds.) - 2015 - new publ.tech..
    The co-evolutionary concept of Three-modal stable evolutionary strategy of Homo sapiens is developed. The concept based on the principle of evolutionary complementarity of anthropogenesis: value of evolutionary risk and evolutionary path of human evolution are defined by descriptive (evolutionary efficiency) and creative-teleological (evolutionary correctly) parameters simultaneously, that cannot be instrumental reduced to others ones. Resulting volume of both parameters define the trends of biological, social, cultural and techno-rationalistic human evolution by two gear mechanism ˗ gene-cultural co-evolution and techno- humanitarian (...)
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  37. Natur im Labor. Themenschwerpunkt in Philosophia Naturalis Bd. 43, Heft 1-2.Gregor Schiemann & Kristian Köchy (eds.) - 2006 - Klostermann..
    Seit Beginn der frühen Neuzeit ist das naturwissenschaftliche Verfahren maßgeblich durch ein neues Konzept geprägt: das Konzept des experimentellen, gestalterischen Eingriffs in die Natur. Es geht nun nicht mehr darum, eine Geschichte der "freien und ungebundenen Natur" (Bacon) zu erzählen, die in ihrem eigenen Lauf belassen und als vollkommene Bildung betrachtet wird. Es geht vielmehr darum, der "gebundenen und bezwungenen Natur" (Bacon) vermittels der experimentellen Tätigkeit des Menschen die Geheimnisse zu entreißen. Diese technisch-praktische Konzeption grenzt sich explizit von den klassischen (...)
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  38. Bacteria, sex, and systematics.L. R. Franklin - 2007 - Philosophy of Science 74 (1):69-95.
    Philosophical discussions of species have focused on multicellular, sexual animals and have often neglected to consider unicellular organisms like bacteria. This article begins to fill this gap by considering what species concepts, if any, apply neatly to the bacterial world. First, I argue that the biological species concept cannot be applied to bacteria because of the variable rates of genetic transfer between populations, depending in part on which gene type is prioritized. Second, I present a critique of phylogenetic (...)
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  39. EVOLUTIONARY RISK OF HIGH HUME TECHNOLOGIES. Article 3. EVOLUTIONARY SEMANTICS AND BIOETHICS.V. T. Cheshko, L. V. Ivanitskaya & V. I. Glazko - 2016 - Integrative Annthropology (1):21-27.
    The co-evolutionary concept of three-modal stable evolutionary strategy of Homo sapiens is developed. The concept based on the principle of evolutionary complementarity of anthropogenesis: value of evolutionary risk and evolutionary path of human evolution are defined by descriptive (evolutionary efficiency) and creative-teleological (evolutionary correctness) parameters simultaneously, that cannot be instrumental reduced to other ones. Resulting volume of both parameters define the vectors of biological, social, cultural and techno-rationalistic human evolution by two gear mechanism — genetic and cultural co-evolution and techno-humanitarian (...)
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  40. Assuming in biology the reality of real virtuality (a come back for entelechy?).Armando Aranda-Anzaldo - 2011 - Ludus Vitalis 19 (36):333-342.
    Since Aristotle the central question in biology was the origin of organic form; a question put in the backyard by neo-Darwinism that considers organic form as a side effect of the interactions between genes and their products. On the other hand, the fashionable notion of self-organization also fails to provide a true causal explanation for organic form. For Aristotle form is both a cause and the principle of intelligibility and this coupled to the classical concepts of potentiality and actuality (...)
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  41. Is it worth to fit the social sciences in the same track as the study of biological evolution?Armando Aranda-Anzaldo - 2000 - Ludus Vitalis 8 (14):213-218.
    For some the gene-centered reductionism that permeates contemporary neo-Darwinism is an obstacle for finding a common explanatory framework for both biological and cultural evolution. Thus social scientists are tempted to find new concepts that might bridge the divide between biology and sociology. Yet since Aristotle we know that the level of explanation must be commensurate with the particular question to be answered. In modern natural science there are many instances where a reductionist approach has failed to provide the (...)
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  42. Kin Selection: A Philosophical Analysis.Jonathan Birch - 2013 - Dissertation, University of Cambridge
    This PhD dissertation examines the conceptual and theoretical foundations of the most general and most widely used framework for understanding social evolution, W. D. Hamilton's theory of kin selection. While the core idea is intuitive enough (when organisms share genes, they sometimes have an evolutionary incentive to help one another), its apparent simplicity masks a host of conceptual subtleties, and the theory has proved a perennial source of controversy in evolutionary biology. To move towards a resolution of these controversies, we (...)
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  43. Do we need an extended evolutionary synthesis?Massimo Pigliucci - 2007 - Evolution 61 (12):2743-2749.
    The Modern Synthesis (MS) is the current paradigm in evolutionary biology. It was actually built by expanding on the conceptual foundations laid out by its predecessors, Darwinism and neo-Darwinism. For sometime now there has been talk of a new Extended Evolutionary Synthesis (EES), and this article begins to outline why we may need such an extension, and how it may come about. As philosopher Karl Popper has noticed, the current evolutionary theory is a theory of genes, and we still lack (...)
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  44. The organism as ontological go-between. Hybridity, boundaries and degrees of reality in its conceptual history.Charles T. Wolfe - 2014 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 1:http://dx.doi.org/10.1016/j.shps.
    The organism is neither a discovery like the circulation of the blood or the glycogenic function of the liver, nor a particular biological theory like epigenesis or preformationism. It is rather a concept which plays a series of roles – sometimes overt, sometimes masked – throughout the history of biology, and frequently in very normative ways, also shifting between the biological and the social. Indeed, it has often been presented as a key-concept in life science and the ‘theorization’ of Life, (...)
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  45. What's the coincidence in debunking?Harjit Bhogal - 2022 - Philosophy and Phenomenological Research 107 (1):147-167.
    Many moral debunking arguments are driven by the idea that the correlation between our moral beliefs and the moral truths is a big coincidence, given a robustly realist conception of morality.One influential response is that the correlation is not a coincidence because there is a common explainer of our moral beliefs and the moral truths. For example, the reason that I believe that I should feed my child is because feeding my child helps them to survive, and natural selection instills (...)
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  46. Culture or Biology? If this sounds interesting, you might be confused.Sebastian Watzl - 2019 - In Jaan Valsinger (ed.), Social Philosophy of Science for the Social Sciences. Springer. pp. 45-71.
    Culture or Biology? The question can seem deep and important. Yet, I argue in this chapter, if you are enthralled by questions about our biological differences, then you are probably confused. My goal is to diagnose the confusion. In debates about the role of biology in the social world it is easy to ask the wrong questions, and it is easy to misinterpret the scientific research. We are intuitively attracted to what is called psychological essentialism, and therefore interpret what is (...)
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  47. (1 other version)Holobiont Evolution: Mathematical Model with Vertical vs. Horizontal Microbiome Transmission.Joan Roughgarden - 2020 - Philosophy, Theory, and Practice in Biology 12 (2).
    A holobiont is a composite organism consisting of a host together with its microbiome, such as a coral with its zooxanthellae. To explain the often intimate integration between hosts and their microbiomes, some investigators contend that selection operates on holobionts as a unit and view the microbiome’s genes as extending the host’s nuclear genome to jointly comprise a hologenome. Because vertical transmission of microbiomes is uncommon, other investigators contend that holobiont selection cannot be effective because a holobiont’s microbiome is an (...)
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  48. Perceptron Connectives in Knowledge Representation.Pietro Galliani, Guendalina Righetti, Daniele Porello, Oliver Kutz & Nicolas Toquard - 2020 - In Pietro Galliani, Guendalina Righetti, Daniele Porello, Oliver Kutz & Nicolas Toquard (eds.), Knowledge Engineering and Knowledge Management - 22nd International Conference, {EKAW} 2020, Bolzano, Italy, September 16-20, 2020, Proceedings. Lecture Notes in Computer Science 12387. pp. 183-193.
    We discuss the role of perceptron (or threshold) connectives in the context of Description Logic, and in particular their possible use as a bridge between statistical learning of models from data and logical reasoning over knowledge bases. We prove that such connectives can be added to the language of most forms of Description Logic without increasing the complexity of the corresponding inference problem. We show, with a practical example over the Gene Ontology, how even simple instances of perceptron connectives (...)
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  49. The Theoretical Difficulties of Memetics.Kinga Kowalczyk-Purol - 2018 - Diametros (58):65-86.
    Memetics is a research approach which applies evolutionary ideas and terminology to cultural phenomena. The core idea of memetics is the existence of the units of cultural evolution which are attributed autonomous replicating goals. Of course, such a controversial concept has gained many devoted adherents as well as its determined opponents. The paper discusses the theoretical difficulties of memetics. The first part discusses the analogy of genes and memes. The theme of the second part is the ontology of a cultural (...)
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  50. The Mechanistic Approach to Psychiatric Classification.Elisabetta Sirgiovanni - 2009 - Dialogues in Philosophy, Mental and Neuro Sciences 2 (2):45-49.
    A Kuhnian reformulation of the recent debate in psychiatric nosography suggested that the current psychiatric classification system (the DSM) is in crisis and that a sort of paradigm shift is awaited (Aragona, 2009). Among possible revolutionary alternatives, the proposed fi ve-axes etiopathogenetic taxonomy (Charney et al., 2002) emphasizes the primacy of the genotype over the phenomenological level as the relevant basis for psychiatric nosography. Such a position is along the lines of the micro-reductionist perspective of E. Kandel (1998, 1999), which (...)
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