The Human Genome Project is regarded by many as one of the major scientific achievements in recent science history, a large-scale endeavour that is changing the way in which biomedical research is done and expected, moreover, to yield considerable benefit for society. Thus, since the completion of the human genome sequencing effort, a debate has emerged over the question whether this effort merits to be awarded a Nobel Prize and if so, who should be the one to receive (...) it, as no more than three individuals can be selected. In this article, the HGP is taken as a case study to consider the ethical question to what extent it is still possible, in an era of big science, of large-scale consortia and global team work, to acknowledge and reward individual contributions to important breakthroughs in biomedical fields. Is it still viable to single out individuals for their decisive contributions in order to reward them in a fair and convincing way? Whereas the concept of the Nobel prize as such seems to reflect an archetypical view of scientists as solitary researchers who, at a certain point in their careers, make their one decisive discovery, this vision has proven to be problematic from the very outset. Already during the first decade of the Nobel era, Ivan Pavlov was denied the Prize several times before finally receiving it, on the basis of the argument that he had been active as a research manager rather than as a researcher himself. The question then is whether, in the case of the HGP, a research effort that involved the contributions of hundreds or even thousands of researchers worldwide, it is still possible to “individualise” the Prize? The “HGP Nobel Prize problem” is regarded as an exemplary issue in current research ethics, highlighting a number of quandaries and trends involved in contemporary life science research practices more broadly. (shrink)

On October 3, 2022, the Nobel Prize in Physiology or Medicine 2022 was awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution”. Svante Pääbo is a Swedish geneticist specializing in evolutionary genetics and contributing to the foundation of paleogenetics.

Dennis Gabor devised a new concept for optical imaging in 1947 that went by a variety of names over the following decade: holoscopy, wavefront reconstruction, interference microscopy, diffraction microscopy and Gaboroscopy. A well-connected and creative research engineer, Gabor worked actively to publicize and exploit his concept, but the scheme failed to capture the interest of many researchers. Gabor’s theory was repeatedly deemed unintuitive and baffling; the technique was appraised by his contemporaries to be of dubious practicality and, at best, constrained (...) to a narrow branch of science. By the late 1950s, Gabor’s subject had been assessed by its handful of practitioners to be a white elephant. Nevertheless, the concept was later rehabilitated by the research of Emmett Leith and Juris Upatnieks at the University of Michigan, and Yury Denisyuk at the Vavilov Institute in Leningrad. What had been judged a failure was recast as a success: evaluations of Gabor’s work were transformed during the 1960s, when it was represented as the foundation on which to construct the new and distinctly different subject of holography, a re-evaluation that gained the Nobel Prize for Physics for Gabor alone in 1971. This paper focuses on the difficulties experienced in constructing a meaningful subject, a practical application and a viable technical community from Gabor’s ideas during the decade 1947-1957. (shrink)

The paper discusses this year’s Nobel Prize in physics for experiments of entanglement “establishing the violation of Bell inequalities and pioneering quantum information science” in a much wider, including philosophical context legitimizing by the authority of the Nobel Prize a new scientific area out of “classical” quantum mechanics relevant to Pauli’s “particle” paradigm of energy conservation and thus to the Standard model obeying it. One justifies the eventual future theory of quantum gravitation as belonging to the (...) newly established quantum information science. Entanglement, involving non-Hermitian operators for its rigorous description, non-unitarity as well as nonlocal and superluminal physical signals “spookily” (by Einstein’s flowery epithet) synchronizing and transferring some nonzero action at a distance, can be considered to be quantum gravity so that its local counterpart to be Einstein’s gravitation according to general relativity therefore pioneering an alternative pathway to quantum gravitation different from the “secondary quantization” of the Standard model. So, the experiments of entanglement once they have been awarded by the Nobel Prize launch particularly the relevant theory of quantum gravitation grounded on “quantum information science” thus granted to be nonclassical quantum mechanics in the shared framework of the generalized quantum mechanics obeying rather quantum-information conservation than only energy conservation. The concept of “dark phase” of the universe naturally linked to the very well confirmed “dark matter” and “dark energy” and opposed to its “light phase” inherent to classical quantum mechanics and the Standard model obeys quantum-information conservation, after which reversible causality or the mutual transformation of energy and information are valid. The mythical Big Bang after which energy conservation holds universally is to be replaced by an omnipresent and omnitemporal medium of decoherence of the dark and nonlocal phase into the light and local phase. The former is only an integral image of the latter and borrowed in fact rather from religion than from science. Physical, methodological and proper philosophical conclusions follow from that paradigm shift heralded by this year’s Nobel Prize in physics. For example, the scientific theory of thinking should originate from the dark phase of the universe, as well: probably only approximately modeled by neural networks physically belonging to the light phase thoroughly. A few crucial philosophical sequences follow from the break of Pauli’s paradigm: (1) the establishment of the “dark” phase of the universe as opposed to its “light” phase, only to which the Cartesian dichotomy of “body” and “mind” is valid; (2) quantum information conservation as relevant to the dark phase, furthermore generalizing energy conservation as to its light phase, productively allowing for physical entities to appear “ex nihilo”, i.e., from the dark phase, in which energy and time are yet inseparable from each other; (3) reversible causality as inherent to the dark phase; (4) the interpretation of gravitation only mathematically: as an interpretation of the incompleteness of finiteness to infinity, for example, following the Gödel dichotomy (“either contradiction or incompleteness”) about the relation of arithmetic to set theory; (5) the restriction of the concept of hierarchy only to the light phase; (6) the commensurability of both physical extremes of a quantum and the universe as a whole in the dark phase obeying quantum information conservation and akin to Nicholas of Cusa’s philosophical and theological worldview. (shrink)

Penrose believed that the universe is a book written in the language of mathematics. Through this language, he disproved the fallacy of coincidence in complex and meaningful systems, reaching philosophical and theological heights by placing things in their proper places based on his induction, and his mindful reasoning.

This paper discusses some ethically relevant aspects of William Nordhaus’s contribution to climate change policy evaluation. Nordhaus's approach can shed light on one—but only one—dimension of the climate change problem. His boldest claims notwithstanding, there is nothing particularly "optimal" about the temperature increases associated with his most famous modeling choices.

On September 3, 2022, Retraction Watch reported that four articles published in the Proceedings of the National Academy of Sciences (PNAS) had been retracted on the same day (02 September 2022). More notable is that all four articles were co-authored by a preeminent researcher on the molecular mechanisms of oxygen regulation – Gregg Semenza. Semenza shared The Nobel Prize in Physiology or Medicine 2019 with William Kaelin and Peter Ratcliffe for “their discoveries of how cells sense and adapt (...) to oxygen availability.”. (shrink)

Throughout history, a relatively small number of individuals have made a profound and lasting impact on science and society. Despite long-standing, multi-disciplinary interests in understanding careers of elite scientists, there have been limited attempts for a quantitative, career-level analysis. Here, we leverage a comprehensive dataset we assembled, allowing us to trace the entire career histories of nearly all Nobel laureates in physics, chemistry, and physiology or medicine over the past century. We find that, although Nobel laureates were energetic (...) producers from the outset, producing works that garner unusually high impact, their careers before winning the prize follow relatively similar patterns as ordinary scientists, being characterized by hot streaks and increasing reliance on collaborations. We also uncovered notable variations along their careers, often associated with the Nobel prize, including shifting coauthorship structure in the prize-winning work, and a significant but temporary dip in the impact of work they produce after winning the Nobel. Together, these results document quantitative patterns governing the careers of scientific elites, offering an empirical basis for a deeper understanding of the hallmarks of exceptional careers in science. (shrink)

The Nobel Prize in Literature laureate Mario Vargas Llosa (2020) praises the legal protection of bullfighting by a Peruvian law that prohibits the torture of animals except in case of cultural traditions, such as bullfighting and cockfighting. He claims that his defense of bullfighting follows from his liberal point of view, and advances three reasons in favor of its preservation: It is a tradition, it is a fine art, and the individuals should be constitutionally free to choose what (...) to see and where to go. I argue that his arguments are morally irrelevant and logically unsound. (shrink)

The Nobel Prize-winning economist Robert Shiller published an article in the American Economic Review in 20171 and a book in 20192 , both carrying the term “narrative economics.”.

Nadine Gordimer, the Nobel prize winning South African author, deals with the complexities of “the Other” in most of her novels. She has grown up in a post-colonial South Africa and lived through the various stages of its apartheid regime. One of her main concerns was to analyze the impact of this discriminating “the other” on people and their culture. -/- .

As historian Henning Schmidgen notes, the scientific study of the nervous system would have been “unthinkable” without the industrialization of communication in the 1830s. Historians have investigated extensively the way nerve physiologists have borrowed concepts and tools from the field of communications, particularly regarding the nineteenth-century work of figures like Helmholtz and in the American Cold War Era. The following focuses specifically on the interwar research of the Cambridge physiologist Edgar Douglas Adrian, and on the technology that led to his (...) Nobel-Prize-winning research, the thermionic vacuum tube. Many countries used the vacuum tube during the war for the purpose of amplifying and intercepting coded messages. These events provided a context for Adrian's evolving understanding of the nerve fiber in the 1920s. In particular, they provide the background for Adrian's transition around 1926 to describing the nerve impulse in terms of “information,” “messages,” “signals,” or even “codes,” and for translating the basic principles of the nerve, such as the all-or-none principle and adaptation, into such an “informational” context. The following also places Adrian's research in the broader context of the changing relationship between science and technology, and between physics and physiology, in the first few decades of the twentieth century. (shrink)

The concept of the cortical column refers to vertical cell bands with similar response properties, which were initially observed by Vernon Mountcastle’s mapping of single cell recordings in the cat somatic cortex. It has subsequently guided over 50 years of neuroscientific research, in which fundamental questions about the modularity of the cortex and basic principles of sensory information processing were empirically investigated. Nevertheless, the status of the column remains controversial today, as skeptical commentators proclaim that the vertical cell bands are (...) a functionally insignificant by-product of ontogenetic development. This paper inquires how the column came to be viewed as an elementary unit of the cortex from Mountcastle’s discovery in 1955 until David Hubel and Torsten Wiesel’s reception of the Nobel Prize in 1981. I first argue that Mountcastle’s vertical electrode recordings served as criteria for applying the column concept to electrophysiological data. In contrast to previous authors, I claim that this move from electrophysiological data to the phenomenon of columnar responses was concept-laden, but not theory-laden. In the second part of the paper, I argue that Mountcastle’s criteria provided Hubel Wiesel with a conceptual outlook, i.e. it allowed them to anticipate columnar patterns in the cat and macaque visual cortex. I argue that in the late 1970s, this outlook only briefly took a form that one could call a ‘theory’ of the cerebral cortex, before new experimental techniques started to diversify column research. I end by showing how this account of early column research fits into a larger project that follows the conceptual development of the column into the present. (shrink)

Hayek’s philosophical psychology as set out in his The Sensory Order (1952) has, for the most part, been neglected. Despite being lauded by computer scientist grandee Frank Rosenblatt and by Nobel prize-winning biologist Gerald Edelman, cognitive scientists -- with a few exceptions -- have yet to discover Hayek’s philosophical psychology. On the other hand, social theorists, Hayek’s traditional disciplinary constituency, have only recently begun to take note and examine the importance of psychology in the complete Hayek corpus. This (...) volume brings together for the first time state-of-the-art contributions from neuroscientists and philosophers of mind as well as economists and social theorists, all critically engaging in many aspects of Hayek’s philosophical psychology. (shrink)

Marie Curie is the first scientist woman awarded the Nobel Prize in Physics (1903) and another in Chemistry (1911). Her life and her work summarize the tenacity, effort and passion for knowing aspects related to the reality of a new physical-chemical phenomenon: radioactivity. In this semblance, in addition to the scientific aspect, the human aspect that accompanies and sometimes overshadows the lives of great men is shown.

The history of holography, the technology of three-dimensional imaging that grew rapidly during the 1960s, has been written primarily by its historical actors and, like many new inventions, its concepts and activities became surrounded by myths and myth-making. The first historical account was disseminated by the central character of this paper, George W. Stroke, while a professor of Electrical Engineering at the University of Michigan. His claims embroiled several workers active in the field of holography and information processing during the (...) 1960s, but transcended personality conflicts: they influenced the early historiography of holography and the awarding of the Nobel Prize for Physics to Dennis Gabor in 1971. An extended discussion of these episodes, based on archival research, publications analysis and interviews with participants, reveals the importance and extraordinary allure of intellectual priority for practicing scientists, and how its history and explanations are woven from multiple accounts and contemporary interpretations. (shrink)

Roderick M. Chisholm (1916-1999) was one of the most important philosophical thinkers of the 20th century. His influence on epistemology (the theory of knowledge) and metaphysics cannot be understated; indeed, it is difficult to conceive of what these fields would be like today without the impact of Chisholm. Were there a Nobel Prize in philosophy, Chisholm surely would have won it.

Dual-process theories of higher order cognition (DPTs) have been enjoying much success, particularly since Kahneman’s 2002 Nobel prize address and recent book Thinking, Fast and Slow (2009). Historically, DPTs have attempted to provide a conceptual framework that helps classify and predict differences in patterns of behavior found under some circumstances and not others in a host of reasoning, judgment, and decision-making tasks. As evidence has changed and techniques for examining behavior have moved on, so too have DPTs. Killing (...) two birds with one stone, Evans and Stanovich (2013, this issue) respond to five main criticisms of DPTs. Along with addressing each criticism in turn, they set out to clarify the essential defining characteristics that distinguish one form of higher order cognition from the other. The aim of this commentary is to consider the defining characteristics of Type 1 and Type 2 processing that have been proposed and to suggest that the evidence can be taken to support quantitative differences rather than qualitatively distinct processes. (shrink)

Arthur Clark and Michael Kube–McDowell (“The Triger”, 2000) suggested the sci-fi idea about the direct transformation from a chemical substance to another by the action of a newly physical, “Trigger” field. Karl Brohier, a Nobel Prize winner, who is a dramatic persona in the novel, elaborates a new theory, re-reading and re-writing Pauling’s “The Nature of the Chemical Bond”; according to Brohier: “Information organizes and differentiates energy. It regularizes and stabilizes matter. Information propagates through matter-energy and mediates the (...) interactions of matter-energy.” Dr Horton, his collaborator in the novel replies: “If the universe consists of energy and information, then the Trigger somehow alters the information envelope of certain substances –“. “Alters it, scrambles it, overwhelms it, destabilizes it” Brohier adds. There is a scientific debate whether or how far chemistry is fundamentally reducible to quantum mechanics. Nevertheless, the fact that many essential chemical properties and reactions are at least partly representable in terms of quantum mechanics is doubtless. For the quantum mechanics itself has been reformulated as a theory of a special kind of information, quantum information, chemistry might be in turn interpreted in the same terms. Wave function, the fundamental concept of quantum mechanics, can be equivalently defined as a series of qubits, eventually infinite. A qubit, being defined as the normed superposition of the two orthogonal subspaces of the complex Hilbert space, can be interpreted as a generalization of the standard bit of information as to infinite sets or series. All “forces” in the Standard model, which are furthermore essential for chemical transformations, are groups [U(1),SU(2),SU(3)] of the transformations of the complex Hilbert space and thus, of series of qubits. One can suggest that any chemical substances and changes are fundamentally representable as quantum information and its transformations. If entanglement is interpreted as a physical field, though any group above seems to be unattachable to it, it might be identified as the “Triger field”. It might cause a direct transformation of any chemical substance by from a remote distance. Is this possible in principle? (shrink)

_La Peste_, originally published in 1947 by the Nobel Prize-winning writer Albert Camus, chronicles the progression of deadly bubonic plague as it spreads through the quarantined Algerian city of Oran. While most discussions of fictional examples within aesthetics are either historical or hypothetical, Camus offers an example of "pestilence fiction." Camus chose fiction to convey facts--about plagues in the past, his own bout with tuberculosis at age seventeen, living under quarantine away from home for several years, and forced (...) separation from his wife who remained in Algiers while he was abroad in Nazi-occupied France. His own lived experiences undergird an imaginative account of shared human realities with which we can identify: vulnerability to the disease, isolation, fear, and finally humanitarianism. _The Plague_ teaches us to neither covet nor expect what we so casually took for granted. This collection of original essays on philosophical themes in _The Plague_ is of special relevance during and in the aftermath of Covid-19 but also provides reflections that will be of lasting value to those interested in this classic work of literature. The novel explores questions of enduring importance. Do we collectively meet the threshold of ethical behavior posed by Camus who wrote, "What's true of all the evils in the world is true of plague as well. It helps men to rise above themselves"? Or does the absurd undermine the compassionate? Do "heroes" dutifully fight a plague with "common decency," or does human nature resign itself to the normalization of uncontrollable suffering and death? There are myriad ways to approach the novel and this volume encourages readers to ponder human dilemmas in fictional Oran informed by our current pandemic. Series editor forward by Richard Eldridge. List of Contributors includes Steven G. Kellman, Jane E. Schultz, Andrew Edgar, Kathleen Higgins, Edward B. Weiser, Cynthia A. Freeland, and Margaret E. Gray; see "Introduction" by Peg Brand Weiser below. (shrink)

This week, the Royal Swedish Academy of Sciences announced the names of Nobel laureates in different fields. This year, the Nobel Prize in Biomedical Sciences was awarded to Swedish geneticist Svante Paabo for his discoveries concerning the DNA sequence of apes and human evolution. His work is especially meaningful as the question of human origin has long been a major concern to mankind. Modern-day wise humans belong to the genus Homo sapiens, along with seven ancient human races (...) that existed millions of years ago. Over time, many species became extinct and Professor Paabo discovered the gene transfer of these extinct species to Homo sapiens. With this discovery, he laid the foundation for other scientists to continue to search for the origin of modern humans. (shrink)

Boscovich' theory of natural philosophy, published in 1758, made a great influence on his peers and had plenty of followers in centuries to come. It contributed to the discovery of atomic structure and inspired many scientists to work on further advancements of modern material structure comprehensions. In 1993, the physicist Leon Ledermann, a Nobel Prize laureate, wrote that 'Boscovich's philosophy is a key for the entire modern physics'. German philosopher Nietzsche regarded Boscovich's theory 'the greatest triumph over the (...) senses that has yet been achieved on earth'. Frenchman Herismann believed that 'the entire Boscovich's philosophy will become a philosophy of the 21st century'. This article includes a presentation of Boscovich's life and activities, description of his philosophy as well as its contributions to modern science and philosophy. (shrink)

The main focus of this paper is to explore the role of African myths, folklore and popular wisdom in discovering self-identity, which are arguably deployed in the novels of the Nobel Prize winning African-American writer and thinker, Toni Morrison, who is quite frequently labelled as a mythical symbolist. In Song of Solomon, Morrison stirs together folk and fairy tale, magic and root medicine, history and imagination, flight and naming for a distinctive fictional concoction. In this novel, she shows (...) impact of slavery on the identity of African Americans and suggests how a strong and complete identity can be constructed. Thus Morrison demonstrates that both an understanding of one’s heritage and ancestral past is necessary and helps to unite with own community. So the paper examines the transformation of the character, Milkman, from an unconcerned man into culturally aware African American and how the sources of Myths, folklore and cultures lay the stepping stone for the development of a complete and coherent identity. (shrink)

It is proposed a critique of existing interpretations of quantum mechanics, both anti-realistic and realistic, and, in particular, the Copenhagen interpretation, the interpretations with hidden variables, the metaphysical interpretation of H. Everett’s interpretation, the many-worlds interpretation by D. Wallace, QBism by C. Fuchs, D. Mermin and R. Schack, the relational interpretation by C. Rovelli, neo-Kantian and phenomenological interpretations by M. Bitbol, the informational interpretation by A. Zeilinger, the Nobel Prize Winner in Physics 2022, and others. As is known (...) compared to classical physics, quantum mechanics is a new physical paradigm. The author argues that from a philosophical point of view quantum mechanics is an anomaly within the paradigm of (post)modern philosophy. A new approach to understanding quantum mechanics and resolving its paradoxes, rejecting the assumptions and prejudices of (post)modern philosophy, is proposed – contextual quantum realism (CQR). It is a moderately deflationary approach that combines elements of (neo-)Copenhagen, informational and realist interpretations and recognizes the possibility of knowing the things themselves. From the point of view of CQR, the measurement problem – the basic problem of philosophy of quantum mechanics – is a pseudo-problem . (shrink)

This article is a translation of the paper in Polish (Alfred Tarski - człowiek, który zdefiniował prawdę) published in Ruch Filozoficzny 4 (4) (2007). It is a personal Alfred Tarski memories based on my stay in Berkeley and visit the Alfred Tarski house for the invitation of Janusz Tarski.

Professor Puran Singh, a unique synthesis of a poet, philosopher and scientist, rose like a celestial star on the firmament of modern Indian literature. The many splendored personality of this great chemist, mystic poet, visionary and interpreter of the Sikh cultural consciousness still beckons scholars to explore the extent of his vision in various fields. After a splendid in-depth study of the Life and Work of Puran Singh, Dr. Hardev Singh Virk has made a successful attempt to unravel the persona (...) of this multi-dimensional genius in his book titled 'Professor Puran Singh - Scientist, Poet and Philosopher.' The book is an anthology of 11 essays - 7 in English and 4 in Punjabi. In the 'Introduction to the book, the author traces a brief history of the kindling of his interest in the 'Life and Works of Puran Singh.' Then he articulates the purpose of the book to elaborate the ideas of this eminent scholar through different mediums to reach a wider audience. Dr. Virk stresses that poetic and other literary works of Puran Singh are of International standards and worth a Nobel Prize in literature. Still, sadly these works have not been adequately projected at the world forum. (shrink)

A cursory glance at the list of Nobel Laureates for Economics is sufficient to confirm Stanovich’s description of the project to evaluate human rationality as seminal. Herbert Simon, Reinhard Selten, John Nash, Daniel Kahneman, and others, were awarded their prizes less for their work in economics, per se, than for their work on rationality, as such. Although philosophical works have for millennia attempted to describe, explicate and evaluate individual and collective aspects of rationality, new impetus was brought to this (...) endeavor over the last century as mathematical logic along with the social and behavioral sciences emerged. Yet more recently, over the last several decades, propelled by the emergence of artificial intelligence, cognitive science, evolutionary psychology, neuropsychology, and related fields, even more sophisticated approaches to the study of rationality have emerged. (shrink)

This paper philosophically explores the possible introduction of an alternative analytical approach to European integration. It is an invitation to reflect critically outside the mainstream paradigm. An extensive amount of scientific literature and research papers focuses on the EU, but it is quite easy to get lost amidst this stream of abundant writing. Meanwhile, the EU has been experiencing serious challenges since the previous enlargement, which has led to a broader definition of the “European project.” Numerous discussions have failed to (...) deliver the expected results. It is an interesting paradox that the EU has been proposed globally as a model of peacebuilding in the context of the Nobel Peace Prize 2012. However, since then, no clearly defined model of internal EU integration has been implemented apart from some basic premises. The Monnet method has become formalized within the official framework of the EU, thus justifying top-down institutional engineering, which is contrary to the concept proposed by Jean Monnet. The paper offers a metaphorical reasoning as an intellectual counterbalance to the unreflective application of integrational models, thus enriching analytical and critical discourse. (shrink)

After being nominated by Martin Luther King, Jr. for the Nobel Peace Prize, the “gentle and fearless” Vietnamese Buddhism monk Thich Nhat Hanh established a worldwide movement called the Order of Interbeing, which deals with major human conflicts with ancient Buddhist teachings. By drawing from original Buddhist texts, Hanh has created an authentic type of religious activism based on mindfulness of our connectedness that has real potential for peace, because of its twin focus on resolution and prevention. In (...) this paper, I discuss how the Order has come into existence, its framework, its cause, how it educates its members, and how effectively it is creating a culture of peace by examining the history of the Order, reading Hanh’s wisdom books and poetry, analyzing its structure, and interviewing a local Sangha on their mystical experiences. I argue that Thich Nhat Hanh’s engaged Buddhism has the potential to make a significant impact on mankind. (shrink)

Worldwide 1.2 million people are dying from kidney failure each year, and in the USA alone, approximately 100 000 people are currently on the waiting list for a kidney transplant. One possible solution to the kidney shortage is for governments to pay donors for one of their healthy kidneys and distribute these kidneys according to need. There are, however, compelling objections to this government-monopsony model. To avoid these objections, I propose a small adjustment to the model. I suggest we reward (...) kidney sellers with both money and a ceremony that celebrates their noble act. They should, in other words, receive a prize rather than a price. (shrink)

We examine two leading theories of rational belief, the Lockean view and the explanationist view. The first is appealing because it fits with some independently plausible claims about the ways that rational persons pursue their aims. The second is appealing because it seems to account for intuitions that cause trouble for the Lockean view. While fitting the intuitive data is desirable, we are troubled that the explanationist view seems to clash with our theoretical beliefs about what rationality must be like. (...) We think that upon further examination, the intuitive appeal of the explanationist view starts to diminish. We also think that these further intuitions that spell trouble for the explanationist spell trouble for any theory that is not expectationist. We propose a novel expectationist theory of rational belief that improves upon the Lockean and the explanationist views. We think that recent defences of the Lockean view contain an important insight. A substantive theory of rational response should be based on a suitable theory of prizes and a suitable theory of how we should pursue prizes in the face of uncertainty. Most theories of rational belief typically take for granted a truth-centred picture of epistemic prizes (e.g., that epistemic desirability and undesirability can be fully understood in terms of accuracy) and then differ in terms of how they recommend pursuing prizes so understood. We think the Lockeans embrace plausible principles of how prizes should be pursued. We trace the difficulties that this view faces to veritistic assumptions about prizes. We suggest that some prizes are epistemically loaded in that a complete description of the prize will itself make reference to our epistemic states or standards. We argue that knowledge matters to rational belief and choice because in the epistemic domain, knowledge is the prize. We see this in practical domains, too. In some choice settings, what's desired is desired, in part, because it involves a kind of connection to reality only knowledge provides. (shrink)

The studies of Svante Pääbo, Nobel Laureate in Physiology or Medicine in 2022 are analyzed in two aspects: firstly, as the most striking example of the evolutionary transformation of classical scienceinto the so-called post-academic (techno)science and, secondly, as an element of the so-called "biopolitical turn" in the socio-humanitarian and political knowledge of technological civilization and, in particular, in the concept of "civil society".

It is our great pleasure to announce that the recipient of the 2020 Everett Mendelsohn Prize is Daniel Liu, whose essay, “The Cell and Protoplasm as Container, Object, and Substance, 1835–1861,” appeared in the Journal of the History of Biology, Volume 50, 4 (2017), pp. 889–925.

Vào ngày 3 tháng 9 năm 2022, Retraction Watch thông báo rằng bốn bài báo được xuất bản trong Proceedings of the National Academy of Sciences (PNAS) đã bị rút vào cùng một ngày (02 tháng 9 năm 2022). Đáng chú ý hơn là cả bốn bài đều có tác giả chung là Gregg Semenza, một nhà nghiên cứu hàng đầu về cơ chế phân tử của quá trình điều chỉnh oxy – Gregg Semenza. Semenza đã chia sẻ Giải (...) class='Hi'>Nobel Y học hoặc Sinh lý 2019 cùng với William Kaelin và Peter Ratcliffe vì "những khám phá về cách tế bào cảm nhận và thích nghi với sự có sẵn của oxy.". (shrink)

This paper will be concerned with hard choices—that is, choice situations where an agent cannot make a rationally justified choice. Specifically, this paper asks: if an agent cannot optimize in a given situation, are they facing a hard choice? A pair of claims are defended in light of this question. First, situations where an agent cannot optimize because of incompleteness of the binary preference or value relation constitute a hard choice. Second, situations where agents cannot optimize because the binary preference (...) or value relation violates acyclicity do not constitute a hard choice. (shrink)

Famously, in the essay Inquiry Concerning the Distinctness of the Principles of Natural Theology and Morality (Prize Essay), Kant attempts to distance himself from the Wolffian model of philosophical inquiry. In this respect, Kant scholars have pointed out Kant’s claim that philosophy should not imitate the method of mathematics and his appeal to Newton’s “analytic method.” In this article, I argue that there is an aspect of Kant’s critique of the Wolffian model that has been neglected. Kant presents a (...) powerful attack of the idea that philosophy should proceed through the analysis of concepts and argues that we should give up the aim of arriving at “complete” concepts as one of its fundamental desiderata. Importantly, this attack of philosophy conceived as conceptual analysis is distinctive and original if one compares it with Kant’s critique of analysis in the Critique of Pure Reason, which rests on the idea that analysis is insufficient to ground substantial metaphysical truths. I also make an additional point: Scholars have debated whether the appeal to Newton’s analytic method involves a form of empiricism. I submit that this debate is ill-conceived because Kant uses a notion of “given concepts” that is indeterminate with respect to their a priori or a posteriori status. (shrink)

Background. A growing interest in discursive nature of Nobel lectures resulted in a number of studies which emphasize their rhetorical force to influence public opinion and to popularize ideas in different spheres of human life. Analyzing Literature Laureates’ lectures, most researchers focus on linguistic means and the personality of the Nobelist himself/herself. However, characteristics of a writer proper have not been dealt with indepth. This article maintains our previous study, which indicates a close relationship between the content component of (...) the Nobel lecture and the laureate’ outlook; the lecture itself can be regarded as a brief but extremely powerful expression of his/her human and professional qualities. -/- Purpose. The aim of this paper is to examine how literature laureates interpret the notion of a writer in their Nobel lectures and to identify main common themes in creating this collective image. -/- Methods. A method of linguistic description and observation, a descriptive method, and a contextual-interpretation method were employed to analyse the sample of 17 Nobel lectures. -/- Results. The outcomes of our study indicate that Nobel lectures are extremely powerful expression of prizewinners’ human and professional qualities. We have devised a set of five themes, namely the writer’s social duty, his/her destiny, literary background, tools, and literary outcome to describe the collective image of a writer. Within the framework of our research, literary background falls into two subthemes (literary heritage and a personal writing process); discussing the writer’s toolkit, we focus on language and words. -/- Discussion. Our findings show that laureates develop the concept “writer” to varying degrees but all of them stress a direct interconnection between an active social position and the writer’s destiny. Further research can involve the in-depth study of a definite Nobel lecture in terms of the compositional structure and employed linguistic means. (shrink)

Peter van Inwagen’s answer to the Special Composition Question, call it Organicism, says the xs compose y iff the activity of the xs constitutes a life. What about suspended lives (i.e., cryptobiosis)? Suppose a cat is alive at t1, completely frozen at t2, then revived at t3. Is the cat alive while frozen? Plausibly no, which according to Organicism means the cat-qua-composite ceases to exist at t2. Intuitively, however, the same cat seems present at all of t1, t2, and t3. (...) To account for these intuitions, van Inwagen modifies his answer: the xs compose y iff the activity of the xs constitutes or results from a life. Alas, this modification permits problematic duplication cases where one collection of objects composes something, yet a duplicate collection does not. This prompts the search for alternative modifications that identify frozen organisms as composites without introducing duplication problems. A dispositional variant is proposed. (shrink)

When Pierre Bourdieu addresses the problem of why people from certain discriminated groups are hardly present in some fields, he emphasizes the role of stylistic factors that cannot be captured in terms of rules. An alternative explanation refers to split systems, both of which can be captured by means of rules.

The pluralist liberal defends a conception of liberal politics grounded in the thesis of value pluralism. Since he argues from a particular metaphysical thesis – value pluralism – to a particular understanding of politics – liberalism – his account will feature two separable, but interrelated, components: a distinctive justification of liberalism, and a conception of politics with distinctive content. The particular flavor of liberalism to which the pluralist is led is a species of what I term “accommodationism” – an understanding (...) that sees as a polity’s central task the accommodation of many divergent conceptions of the good life. I argue that the pluralist liberal’s case is hampered by four difficulties. Two of these difficulties challenge the justification of liberalism in terms of value pluralism, and two of them plague the particular accommodationist understanding of liberalism to which the pluralist is led. I conclude by arguing that classical liberalism is a view that is immune to these latter two criticisms. In fact, I suggest a more general claim: that classical liberalism provides the most promising resources for the articulation and defense of a conception of politics dedicated to accommodating the diverse and heterogeneous versions of human flourishing countenanced by value pluralism. (shrink)

In this article Johann David Michaelis’s views of language and translation are juxtaposed with his own experience as a translated and translating author, especially with regard to the translations of his prize essay on the reciprocal influence of language and opinions (1759). Its French version originated in a close collaboration with the translators, while the pirated English edition was anonymously translated at second hand. The article reconstructs Michaelis’s relationship with the French translators and his renouncement of the English version, (...) publicly condemned in London by Robert Lowth at the author’s request. These two processes represent different contemporary modes of translation and shed new light on emerging theories of linguistic and cultural transfer. (shrink)

In this article Johann David Michaelis’s views of language and translation are juxtaposed with his own experience as a translated and translating author, especially with regard to the translations of his prize essay on the reciprocal influence of language and opinions (1759). Its French version originated in a close collaboration with the translators, while the pirated English edition was anonymously translated at second hand. The article reconstructs Michaelis’s relationship with the French translators and his renouncement of the English version, (...) publicly condemned in London by Robert Lowth at the author’s request. These two processes represent different contemporary modes of translation and shed new light on emerging theories of linguistic and cultural transfer. (shrink)

There are good, even if inconclusive, reasons to think that cognitive penetration of perception occurs: that cognitive states like belief causally affect, in a relatively direct way, the contents of perceptual experience. The supposed importance of – indeed as it is suggested here, what is definitive of – this possible phenomenon is that it would result in important epistemic and scientific consequences. One interesting and intuitive consequence entirely unremarked in the extant literature concerns the perception of art. Intuition has it (...) that knowledge about art changes how one aesthetically evaluates artworks. A profound explanation of this intuitive fact is that perceptual experiences vary with artistic expertise. Cognitive penetration provides an explanatory mechanism for this latter effect. What one knows or otherwise thinks about art may affect, in one of two ways sketched below, how one perceives art. Differences in aesthetic evaluation may follow, either because high-level aesthetic properties can be perceptually represented or because they causally depend on low-level perceptible properties. All of this lends credence to the hypothesis that the expert better judges art because she better perceives art. And she better perceives art because she better knows art. (shrink)

Recenze: Biagioli, Mario - Riskin, Jessica. Nature Engaged: Science in Practice from the Renaissance to the Present. New York: Palgrave Macmillan 2012, 301 s.

Ngày xuân, đi du xuân trên Internet. Có thời gian lang thang tìm đọc, cũng là niềm vui với người làm nghề nghĩ-viết. Thế rồi, tình cờ ghé thăm cửa “đền” ETH Zürich, bỗng lại có một niềm vui khác: gặp lại “người quen”. Ấy chính là cuốn sách A New Theory of Serendipity, trong đó, tôi tham gia một số chương [1]. Nay đã có sự hiện diện trong ETH Library. -/- Gọi ETH Zürich là một ngôi đền khoa (...) học nhân loại chẳng có gì quá. Nơi đây, 32 giáo sư giải thưởng Nobel đã được trao gửi. Nhà bác học vật lý vĩ đại nhất thế kỷ XX, và cũng của mọi thời đại, Albert Einstein là sinh viên, sau đó là giáo sư tại chính nơi này. Đây là nơi Einstein đặt nền móng cho rất nhiều tư tưởng lớn suốt cuộc đời. (shrink)

Denis Nobel looks at four important misinterpretations of molecular biology concerning evolutionary processes and demonstrates that the new synthesis today looks rather outdated. The modern synthesis is nearly 80 years old. The proponents who worked out the modern synthesis had no access to the current knowledge on cell biology, genetics, epigenetics, RNA biology and virology. Therefore this contribution adds several aspects which Nobel’s article does not explicitly mention, providing some examples for a better understanding of evolutionary novelty.