Results for 'Preimplantation Genetic Diagnosis'

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  1. Preimplantation genetic diagnosis and rational choice under risk or uncertainty.Tomasz Żuradzki - 2014 - Journal of Medical Ethics 40 (11):774-778.
    In this paper I present an argument in favour of a parental duty to use preimplantation genetic diagnosis (PGD). I argue that if embryos created in vitro were able to decide for themselves in a rational manner, they would sometimes choose PGD as a method of selection. Couples, therefore, should respect their hypothetical choices on a principle similar to that of patient autonomy. My thesis shows that no matter which moral doctrine couples subscribe to, they ought to (...)
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  2. Sex Selection and Preimplantation Genetic Diagnosis: A Response to the Ethics Committee of the American Society for Reproductive Medicine.Edgar Dahl & Julian Savulescu - 2000 - Human Reproduction 15 (9):1879-1880.
    In its recent statement 'Sex Selection and Preimplantation Genetic Diagnosis', the Ethics Committee of the American Society of Reproductive Medicine concluded that preimplantation genetic diagnosis for sex selection for non-medical reasons should be discouraged because it poses a risk of unwarranted gender bias, social harm, and results in the diversion of medical resources from genuine medical need. We critically examine the arguments presented against sex selection using preimplantation genetic diagnosis. We argue (...)
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  3. A situation of ethical limbo and preimplantation genetic diagnosis.Tomasz Żuradzki - 2014 - Journal of Medical Ethics 40 (11):780-781.
    In my previous paper I argued that if in vitro fertilization (IVF) is legal and practiced there is no moral ground to object to legalization of preimplantation genetic diagnosis (PGD). My opponent raises an objection that my paper “fails to address the ethical argumentation of one key opponent of IVF – the Catholic Church”. In this reply I show that her/his thesis that embryos created during IVF are in ‘ethical limbo’ and “fall outside the moral universe of (...)
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  4. Response to Tomasz Zuradzki's Preimplantation genetic diagnosis and rational choice under risk or uncertainty.Xavier Symons - 2014 - Journal of Medical Ethics 40 (11):779-779.
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  5. Should Parents Be Allowed to Use Preimplantation Genetic Diagnosis to Choose the Sexual Orientation of Their Children?Edgar Dahl - 2003 - Human Reproduction and Genetic Ethics 18 (7):1368-1369.
    Extending the application of preimplantation genetic diagnosis (PGD) to screen embryos for non-medical traits such as gender, height and intelligence, raises serious moral, legal, and social issues. In this paper I consider the possibility of using PGD to select the sexual orientation of offspring. After considering ®ve potential objections, I conclude that parents should be permitted to use PGD to choose the sexual orientation of their children.
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  6. Procreative Beneficence and Genetic Enhancement.Walter Veit - 2018 - Kriterion - Journal of Philosophy 32 (1):75-92.
    Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful albeit unrealistic. However, recent scienti c breakthroughs in genetic engineering, namely CRISPR/Cas bring the question into public discourse, how the genetic enhancement of humans should be evaluated morally. In 2001, when preimplantation genetic diagnosis (PGD) and in vitro fertilisation (IVF), enabled parents to select between multiple embryos, Julian Savulescu introduced the principle of procreative bene cence (PPB), stating that parents (...)
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  7. Human Genetic Technology, Eugenics, and Social Justice.W. Malcolm Byrnes - 2001 - The National Catholic Bioethics Quarterly 1 (4):555-581.
    In this new post-genomic age of medicine and biomedical technology, there will be novel approaches to understanding disease, and to finding drugs and cures for diseases. Hundreds of new “disease genes” thought to be the causative agents of various genetic maladies will be identified and added to the list of hundreds of such genes already identified. Based on this knowledge, many new genetic tests will be developed and used in genetic screening programs. Genetic screening is the (...)
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  8. Gibt es einen therapeutischen Imperativ zum genome editing in der menschlichen Keimbahn? [Is there a therapeutic imperative for editing the human germline genome? / Existe-t-il un impératif thérapeutique à l'édition du génome dans la lignée germinale humaine].Karla Alex & Christoph Rehmann-Sutter - 2022 - URPP Human Reproduction Reloaded | H2R (University of Zurich), Working Paper Series, 05/2022. Zurich and Geneva: Seismo 1 (5):1-21.
    Abstract: This working paper focuses on the question whether there is a therapeutic imperative that, in specific situations, would oblige us to perform genome editing at the germline level in the context of assisted reproduction. The answer to this central question is discussed primarily with reference to specific scenarios where preimplantation genetic diagnosis (PGD) does not represent an acceptable alternative to germline genome editing based on either medical, or ethical, or – from the perspective of the potential (...)
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  9. Ethical Attitudes of German Specialists in Reproductive Medicine and Legal Regulation of Preimplantation Sex Selection in Germany.Edgar Dahl - 2013 - PLoS ONE 8 (2).
    The majority of German specialists in reproductive medicine opposes preimplantation sex selection for nonmedical reasons while recommending preimplantation sex selection for medical reasons, e.g. X-linked diseases like haemophilia.
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  10. Affecting future individuals: Why and when germline genome editing entails a greater moral obligation towards progeny.Davide Battisti - 2021 - Bioethics 35 (5):1-9.
    Assisted reproductive technologies have greatly increased our control over reproductive choices, leading some bioethicists to argue that we face unprecedented moral obligations towards progeny. Several models attempting to balance the principle of procreative autonomy with these obligations have been proposed. The least demanding is the minimal threshold model (MTM), according to which every reproductive choice is permissible, except creating children whose lives will not be worth living. Hence, as long as the future child is likely to have a life worth (...)
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  11. Nowa liberalna eugenika: krytyczny przegląd argumentów przeciwko biomedycznemu poprawianiu ludzkiej kondycji fizycznej lub umysłowej.Tomasz Żuradzki - 2014 - Diametros 42:204-226.
    Celem artykułu jest krytyka kilku popularnych argumentów przeciwko wykorzystywaniu współczesnych osiągnięć biomedycznych do poprawiania ludzkiej kondycji fizycznej lub umysłowej. Na przykładzie prac Habermasa, Sandela, Fukuyamy omówię trzy argumenty tego typu odwołujące się do: 1) autonomii; 2) życia jako daru; 3) naturalnej równowagi. Na koniec pokażę, że sprzeciw względem niektórych propozycji biomedycznego polepszenia kondycji ludzkiej może być wynikiem swoistego błędu poznawczego, który psychologowie określają jako efekt status quo.
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  12. Attitudes, intentions and procreative responsibility in current and future assisted reproduction.Davide Battisti - 2023 - Bioethics 37 (5):449-461.
    Procreative obligations are often discussed by evaluating only the consequences of reproductive actions or omissions; less attention is paid to the moral role of intentions and attitudes. In this paper, I assess whether intentions and attitudes can contribute to defining our moral obligations with regard to assisted reproductive technologies already available, such as preimplantation genetic diagnosis (PGD), and those that may be available in future, such as reproductive genome editing and ectogenesis, in a way compatible with person‐affecting (...)
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  13. Wunschkind mit Behinderung – Rechtsethische Überlegungen zur gezielten Vererbung genetischer Defekte.Frank Dietrich - 2013 - Archiv für Rechts- und Sozialphilosophie 99 (3):381-399.
    By the example of deafness the article examines the ethical problems that arise when preimplantation genetic diagnosis is used for the intentional heredity of genetic defects. In the first two sections the relevant rules of the German Embryo Protection Law and the motives of deaf couples to desire a handicapped child are explained. Subsequently, it is asked whether the positive selection of genetic defects can harm or otherwise wrong the future child. Moreover, a possible duty (...)
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  14. The new (liberal) eugenics.Nicolae Sfetcu - manuscript
    Despite the Nazi horrors, in 1953 the new eugenics was founded, when Watson and Crick postulated the double helix of DNA as the basis of chemical heredity. In 1961, scientists have deciphered the genetic code of DNA, laying the groundwork for code manipulation and the potential building of new life forms. After thirty years from the discovery of the DNA structure, the experimenters began to carry out the first clinical studies of human somatic cell therapy. The practice of prenatal (...)
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  15. Niepewność na temat moralnego statusu embrionów ludzkich a preimplantacyjna diagnostyka genetyczna.Tomasz Żuradzki - 2012 - Diametros 34:179-189.
    W tekście omawiam tę część internetowej dyskusji, przeprowadzonej w listopadzie 2012 r. na stronie Polskiego Towarzystwa Bioetycznego, która dotyczyła niepewności na temat moralnego statusu embrionów ludzkich. W trakcie dyskusji PTB na temat Stanowiska Komitetu Bioetyki przy Prezydium PAN w sprawie preimplantacyjnej diagnostyki genetycznej (PDG) pojawił się następujący argument: skoro spór o moralny status embrionu jest nierozstrzygalny, to powinniśmy opowiedzieć się przeciwko moralnej dopuszczalności wykonywania PDG na embrionach, a także przeciwko prawnej dopuszczalności tego rodzaju diagnostyki. W tekście omawiam tezy Stanowiska i (...)
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  16. The diagnosis of mental disorders: the problem of reification.Steven Edward Hyman - 2010 - Annual Review of Clinical Psychology 6:155-179.
    A pressing need for interrater reliability in the diagnosis of mental disorders emerged during the mid-twentieth century, prompted in part by the development of diverse new treatments. The Diagnostic and Statistical Manual of Mental Disorders (DSM), third edition answered this need by introducing operationalized diagnostic criteria that were field-tested for interrater reliability. Unfortunately, the focus on reliability came at a time when the scientific understanding of mental disorders was embryonic and could not yield valid disease definitions. Based on accreting (...)
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  17. Genetic Testing for Sale: Implications of Commercial Brca Testing in Canada.Bryn Williams-Jones - 2002 - Dissertation, The University of British Columbia (Canada)
    Ongoing research in the fields of genetics and biotechnology hold the promise of improved diagnosis and treatment of genetic diseases, and potentially the development of individually tailored pharmaceuticals and gene therapies. Difficulty, however, arises in determining how these services are to be evaluated and integrated equitably into public health care systems such as Canada's. The current context is one of increasing fiscal restraint on the part of governments, limited financial resources being dedicated to health care, and rising costs (...)
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  18. Habermas and the Question of Bioethics.Hille Haker - 2019 - European Journal for Philosophy of Religion 11 (4):61-86.
    In The Future of Human Nature, Jürgen Habermas raises the question of whether the embryonic genetic diagnosis and genetic modification threatens the foundations of the species ethics that underlies current understandings of morality. While morality, in the normative sense, is based on moral interactions enabling communicative action, justification, and reciprocal respect, the reification involved in the new technologies may preclude individuals to uphold a sense of the undisposability of human life and the inviolability of human beings that (...)
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  19. Ethical issues in genomics research on neurodevelopmental disorders: a critical interpretive review.Signe Mezinska, L. Gallagher, M. Verbrugge & E. M. Bunnik - 2021 - Human Genomics 16 (15).
    Background Genomic research on neurodevelopmental disorders (NDDs), particularly involving minors, combines and amplifies existing research ethics issues for biomedical research. We performed a review of the literature on the ethical issues associated with genomic research involving children affected by NDDs as an aid to researchers to better anticipate and address ethical concerns. Results Qualitative thematic analysis of the included articles revealed themes in three main areas: research design and ethics review, inclusion of research participants, and communication of research results. Ethical (...)
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  20. The Disability Bioethics Reader.Joel Michael Reynolds & Christine Wieseler (eds.) - 2022 - Oxford; New York: Routledge.
    Introductory and advanced textbooks in bioethics focus almost entirely on issues that disproportionately affect disabled people and that centrally deal with becoming or being disabled. However, such textbooks typically omit critical philosophical reflection on disability, lack engagement with decades of empirical and theoretical scholarship spanning the social sciences and humanities in the multidisciplinary field of disability studies, and avoid serious consideration of the history of disability activism in shaping social, legal, political, and medical understandings of disability over the last fifty (...)
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  21.  76
    (1 other version)Ethical Issues in Pre-Cancer Testing: The Parallel with Huntington's Disease.Donna L. Dickenson - 2002 - In K. W. M. Fulford, Donna Dickenson & Thomas H. Murray (eds.), Healthcare Ethics and Human Values: An Introductory Text with Readings and Case Studies. Malden, Mass.: Wiley-Blackwell. pp. 97.
    This article, based on a case study, examines issues of confidentiality and family impact in a diagnosis of Huntington's disease. Genetic-based illness transcends individualistic models of patient autonomy because it also involves other family members, requiring a new approach to patient confidentiality.
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  22. Kuhn’s “wrong turning” and legacy today.Yafeng Shan - 2020 - Synthese 197 (1):381-406.
    Alexander Bird indicates that the significance of Thomas Kuhn in the history of philosophy of science is somehow paradoxical. On the one hand, Kuhn was one of the most influential and important philosophers of science in the second half of the twentieth century. On the other hand, nowadays there is little distinctively Kuhn’s legacy in the sense that most of Kuhn’s work has no longer any philosophical significance. Bird argues that the explanation of the paradox of Kuhn’s legacy is that (...)
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  23. Gay Science: Assisted Reproductive Technologies and the Sexual Orientation of Children.Timothy F. Murphy - 2005 - Reproductive Biomedicine Online 10 (Sup. 1):102-106.
    There are no technologies at the present time that would allow parents to select the sexual orientation of their children. But what if there were? Some commentators believe that parents should be able to use those techniques so long as they are effective and safe. Others believe that these techniques are unethical because of the dangers they pose to homosexual men and women in general. Both sides point to motives and consequences when trying to analyse the ethics of this question. (...)
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  24.  50
    Cloud-Enabled Risk Management of Cardiovascular Diseases Using Optimized Predictive Machine Learning Models.Kannan K. S. - 2024 - Journal of Science Technology and Research (JSTAR) 5 (1):460-475.
    Data preparation, feature engineering, model training, and performance evaluation are all part of the study methodology. To ensure reliable and broadly applicable models, we utilize optimization techniques like Grid Search and Genetic Algorithms to precisely adjust model parameters. Features including age, blood pressure, cholesterol levels, and lifestyle choices are employed as inputs for the machine learning models in the dataset, which consists of patient medical information. The predictive capacity of the model is evaluated using evaluation measures, such as accuracy, (...)
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  25. Phenomenology and Dimensional Approaches to Psychiatric Research and Classification.Anthony Vincent Fernandez - 2019 - Philosophy, Psychiatry, and Psychology 26 (1):65-75.
    Contemporary psychiatry finds itself in the midst of a crisis of classification. The developments begun in the 1980s—with the third edition of the Diagnostic and Statistical Manual of Mental Disorders —successfully increased inter-rater reliability. However, these developments have done little to increase the predictive validity of our categories of disorder. A diagnosis based on DSM categories and criteria often fails to accurately anticipate course of illness or treatment response. In addition, there is little evidence that the DSM categories link (...)
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  26. Blumenberg, Worldmaking, and Belatedness.José Luis Fernández - 2021 - Journal of Interdisciplinary History of Ideas 10 (20):1-46.
    The Blumenberg-Löwith 'debate' over the 'secularization hypothesis' is an evocative clash that has remained a matter of discussion both inside and outside of the mid-twentieth century German tradition, which has yet to register fully the implications of Blumenberg’s work on the topic of modernity. On one side is Hans Blumenberg, who perceives modernity as justified on its own terms. On the other side is Karl Löwith, who does not recognize a substantive break between modernity and its epochal genetic precursors. (...)
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  27. Precision Medicine and Big Data: The Application of an Ethics Framework for Big Data in Health and Research.G. Owen Schaefer, E. Shyong Tai & Shirley Sun - 2019 - Asian Bioethics Review 11 (3):275-288.
    As opposed to a ‘one size fits all’ approach, precision medicine uses relevant biological, medical, behavioural and environmental information about a person to further personalize their healthcare. This could mean better prediction of someone’s disease risk and more effective diagnosis and treatment if they have a condition. Big data allows for far more precision and tailoring than was ever before possible by linking together diverse datasets to reveal hitherto-unknown correlations and causal pathways. But it also raises ethical issues relating (...)
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  28.  50
    Hybrid Cloud-Machine Learning Framework for Efficient Cardiovascular Disease Risk Prediction and Treatment Planning.Kannan K. S. - 2024 - Journal of Science Technology and Research (JSTAR) 5 (1):460-480.
    Data preparation, feature engineering, model training, and performance evaluation are all part of the study methodology. To ensure reliable and broadly applicable models, we utilize optimization techniques like Grid Search and Genetic Algorithms to precisely adjust model parameters. Features including age, blood pressure, cholesterol levels, and lifestyle choices are employed as inputs for the machine learning models in the dataset, which consists of patient medical information. The predictive capacity of the model is evaluated using evaluation measures, such as accuracy, (...)
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  29. Noise from the Periphery in Autism.Maria Brincker & Elizabeth B. Torres - 2013 - Frontiers in Integrative Neuroscience 7:34.
    No two individuals with the autism diagnosis are ever the same—yet many practitioners and parents can recognize signs of ASD very rapidly with the naked eye. What, then, is this phenotype of autism that shows itself across such distinct clinical presentations and heterogeneous developments? The “signs” seem notoriously slippery and resistant to the behavioral threshold categories that make up current assessment tools. Part of the problem is that cognitive and behavioral “abilities” typically are theorized as high-level disembodied and modular (...)
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  30. Autism: The Very Idea.Simon Cushing - 2012 - In Jami L. Anderson & Simon Cushing (eds.), The Philosophy of Autism. Rowman & Littlefield Publishers. pp. 17-45.
    If each of the subtypes of autism is defined simply as constituted by a set of symptoms, then the criteria for its observation are straightforward, although, of course, some of those symptoms themselves might be hard to observe definitively. Compare with telling whether or not someone is bleeding: while it might be hard to tell if someone is bleeding internally, we know what it takes to find out, and when we have the right access and instruments we can settle the (...)
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  31. The Quest for System-Theoretical Medicine in the COVID-19 Era.Felix Tretter, Olaf Wolkenhauer, Michael Meyer-Hermann, Johannes W. Dietrich, Sara Green, James Marcum & Wolfram Weckwerth - 2021 - Frontiers in Medicine 8:640974.
    Precision medicine and molecular systems medicine (MSM) are highly utilized and successful approaches to improve understanding, diagnosis, and treatment of many diseases from bench-to-bedside. Especially in the COVID-19 pandemic, molecular techniques and biotechnological innovation have proven to be of utmost importance for rapid developments in disease diagnostics and treatment, including DNA and RNA sequencing technology, treatment with drugs and natural products and vaccine development. The COVID-19 crisis, however, has also demonstrated the need for systemic thinking and transdisciplinarity and the (...)
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  32. A Dash of Autism.Jami L. Anderson - 2012 - In Jami L. Anderson & Simon Cushing (eds.), The Philosophy of Autism. Rowman & Littlefield Publishers.
    In this chapter, I describe my “post-diagnosis” experiences as the parent of an autistic child, those years in which I tried, but failed, to make sense of the overwhelming and often nonsensical information I received about autism. I argue that immediately after being given an autism diagnosis, parents are pressured into making what amounts to a life-long commitment to a therapy program that (they are told) will not only dramatically change their child, but their family’s financial situation and (...)
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  33. Peripatetic Perversions.Dirk Baltzly - 2003 - The Monist 86 (1):3-29.
    The idea that there is a coherent and morally relevant concept of sexual perversions has been increasingly called into question. In what follows, I will be concerned with two recent attacks on the notion of sexual perversion: those of Graham Priest and Igor Primoratz. Priest’s paper is the deeper of the two. Primoratz goes methodically through various accounts of sexual perversion and finds difficulties in them. This is no small task, of course, but unlike Priest he does not attempt to (...)
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  34. Has Autism Changed?Simon Cushing - 2016 - In Monika dos Santos & Jean-Francois Pelletier (eds.), The Social Construction and Experiences of Madness. Inter-Disciplinary Press. pp. 75-94.
    The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM) was published in 2013 containing the following changes from the previous edition: gone are the subcategories ‘Autistic Disorder,’ ‘Asperger Syndrome’ and ‘PDD-NOS,’ replaced by the single diagnosis ‘Autism Spectrum Disorder,’ and there is a new category ‘Social Communication Disorder.’ In this paper I consider what kind of reasons would justify these changes if one were (a) a realist about autism, or (b) one were a constructivist. I (...)
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  35. Új szülők, új gyermekek: Miképpen változtatja meg szülői felelősségünket a reprodukciós medicina.Gusztáv Kovács - 2014 - PPHF.
    The book discusses the development of reproductive medicine from the perspective of the parent-child relationship. -/- A könyv a reprodukciós medicina fejlődését vizsgálja a szülői felelősség szempontjából.
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  36. Food Allergy and Philagrine Mutation in Children with Atopic Dermatitis.Gülşah Duyuler Ayçin - 2022 - European Journal of Therapeutics 28 (1):57-61.
    Objective: To determine the frequency and type of food allergy in patients having atopic dermatitis and to show the presence of mutations genetically. -/- Methods: Patients diagnosed as having atopic dermatitis according to the Hanifin Rajka criteria were evaluated retrospectively. Eosinophils, total immunoglobin E, milk-specific immunoglobulin E, egg-specific immunoglobulin E, wheat-specific immunoglobulin E, and filaggrin gene mutation results were recorded. Nutrient elimination was performed for 1 month in patients who were thought to have food allergy owing to skin prick test (...)
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  37. The Humanistic Paradigm and Bio-Psyhco-Social Approach as a Basis of Social Support for People with Mental Health Problems.Nataliia Bondarenko - 2018 - Psychology and Psychosocial Interventions 1:8-14.
    The article discusses the actual problem of social support for people with mental health problems, which has an important place in the study field of social psychology and social work.The article also deals with the definition of the concept of “mental health”, the problem of introducing the term “mental health problems” as a way to avoid stigmatization, and the spread of a humanistic attitude to persons with a psychiatric diagnosis. It also discussed modern theoretical approaches that offer an understanding (...)
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  38.  36
    REVISÃO DE LITERATURA: CISTOS OVARIANOS EM VACAS.G. M. GONÇALVES - 2023 - Dissertation, Universidade Federal Do Norte Do Tocantins
    RESUMO Durante o período de 14 de agosto a 25 de outubro de 2023, a empresa ABS Pecplan possibilitou uma visão abrangente das atividades de reprodução assistida em bovinos por meio do estágio realizado. Sob a supervisão do Médico Veterinário Layson Silva de Souza e orientação do Professor Dr. Márcio Gianordoli Teixeira Gomes, a carga horária totalizou 390 horas. A empresa atua nas áreas de inovulação de embriões, aspiração folicular, diagnóstico gestacional e fertilização in vitro em fazendas nos estados do (...)
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  39. Genetic Affinity and the Right to ‘Three-parent IVF’.G. Owen Schaefer & Markus Labude - 2017 - Journal of Assisted Reproduction and Genetics 34 (12):1577-1580.
    With the recent report of a live birth after use of Mitochondrial replacement therapy, sometimes called ‘Three-parent IVF’, the clinical application of the technique is fast becoming a reality. While the United Kingdom allows the procedure under regulatory scrutiny, it remains effectively outlawed in many other countries. We argue that such prohibitions may violate individuals’ procreative rights, grounded in individuals’ interest in genetic affinity. The interest in genetic affinity was recently endorsed by Singapore’s highest court, reflecting an emphasis (...)
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  40. Rationality, diagnosis and patient autonomy.Jillian Craigie & Lisa Bortolotti - 2014 - Oxford Handbook Psychiatric Ethics.
    In this chapter, our focus is the role played by notions of rationality in the diagnosis of mental disorders, and in the practice of overriding patient autonomy in psychiatry. We describe and evaluate different hypotheses concerning the relationship between rationality and diagnosis, raising questions about what features underpin psychiatric categories. These questions reinforce widely held concerns about the use of diagnosis as a justification for overriding autonomy, which have motivated a shift to mental incapacity as an alternative (...)
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  41. Diagnosis and Causal Explanation in Psychiatry.Hane Htut Maung - 2016 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 60 (C):15-24.
    In clinical medicine, a diagnosis can offer an explanation of a patient's symptoms by specifying the pathology that is causing them. Diagnoses in psychiatry are also sometimes presented in clinical texts as if they pick out pathological processes that cause sets of symptoms. However, current evidence suggests the possibility that many diagnostic categories in psychiatry are highly causally heterogeneous. For example, major depressive disorder may not be associated with a single type of underlying pathological process, but with a range (...)
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  42. Warranted Diagnosis.David Limbaugh, David Kasmier, Werner Ceusters & Barry Smith - 2019 - In David Limbaugh, David Kasmier, Werner Ceusters & Barry Smith (eds.), Proceedings of the International Conference on Biomedical Ontology (ICBO), Buffalo, NY. Buffalo: pp. 1-10.
    A diagnostic process is an investigative process that takes a clinical picture as input and outputs a diagnosis. We propose a method for distinguishing diagnoses that are warranted from those that are not, based on the cognitive processes of which they are the outputs. Processes designed and vetted to reliably produce correct diagnoses will output what we shall call ‘warranted diagnoses’. The latter are diagnoses that should be trusted even if they later turn out to have been wrong. Our (...)
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  43. Non-genetic inheritance: Evolution above the organismal level.Anton Sukhoverkhov & Nathalie Gontier - 2021 - Biosystems 1 (200):104325.
    The article proposes to further develop the ideas of the Extended Evolutionary Synthesis by including into evolutionary research an analysis of phenomena that occur above the organismal level. We demonstrate that the current Extended Synthesis is focused more on individual traits (genetically or non-genetically inherited) and less on community system traits (synergetic/organizational traits) that characterize transgenerational biological, ecological, social, and cultural systems. In this regard, we will consider various communities that are made up of interacting populations, and for which the (...)
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  44. Genetically caused trait is an interactive kind.Riin Kõiv - 2023 - European Journal for Philosophy of Science 13 (3):1-25.
    In this paper I argue that the extent to which a human trait is genetically caused can causally depend upon whether the trait is categorized within human genetics as genetically caused. This makes the kindgenetically caused traitan interactive kind. I demonstrate that this thesis is both conceptually coherent and empirically plausible. I outline the core rationale of this thesis and demonstrate its conceptual coherence by drawing upon Waters’ (2007) analysis of genetic causation. I add empirical plausibility to the thesis (...)
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  45. Genetically engineered mosquitoes, Zika and other arboviruses, community engagement, costs, and patents: Ethical issues.Zahra Meghani & Christophe Boëte - 2018 - PLoS Neglected Tropical Diseases 7 (12).
    Genetically engineered (GE) insects, such as the GE OX513A Aedes aegypti mosquitoes, have been designed to suppress their wild-type populations so as to reduce the transmission of vector-borne diseases in humans. Apart from the ecological and epidemiological uncertainties associated with this approach, such biotechnological approaches may be used by individual governments or the global community of nations to avoid addressing the underlying structural, systemic causes of those infections... We discuss here key ethical questions raised by the use of GE mosquitoes, (...)
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  46. Genetic enhancement, human extinction, and the best interests of posthumanity.Jon Rueda - 2022 - Bioethics (6):529-538.
    The cumulative impact of enhancement technologies may alter the human species in the very long-term future. In this article, I will start showing how radical genetic enhancements may accelerate the conversion into a novel species. I will also clarify the concepts of ‘biological species’, ‘transhuman’ and ‘posthuman’. Then, I will summarize some ethical arguments for creating a transhuman or posthuman species with a substantially higher level of well-being than the human one. In particular, I will present what I shall (...)
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  47. Designing Genetic Engineering Technologies For Human Values.Steven Umbrello - 2022 - Etica E Politica (2):481-510.
    Genetic engineering technologies are a subclass of the biotechnology family, and are concerned with the use of laboratory-based technologies to intervene with a given organism at the genetic level, i.e., the level of its DNA. This class of technologies could feasibly be used to treat diseases and disabilities, create disease-resistant crops, or even be used to enhance humans to make them more resistant to certain environmental conditions. However, both therapeutic and enhancement applications of genetic engineering raise serious (...)
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  48. Lesson from COVID-19 diagnosis and infectious disease prevention for future.Pattamawadee Sankheangaew - manuscript
    This paper has two objectives 1) to study the influence of digital and new technology on COVID-19 diagnosis and healthcare 2) To propose the integral guideline solutions of the infectious disease for the future. COVID-19 stands for corona (CO), virus (VI), disease (D), or SARS-CoV-2, is a respiratory virus first identified in December 2019 in Wuhan, China(WHO, 2019). It is an epidemiological crisis that caused the deaths and sudden destruction of wealth and health of people around the world. Many (...)
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  49. Genetics on the neurodiversity spectrum: Genetic, phenotypic and endophenotypic continua in autism and ADHD.Polaris Koi - 2021 - Studies in History and Philosophy of Science Part A 89 (October 2021):52–62.
    How we ought to diagnose, categorise and respond to spectrum disabilities such as autism and Attention Deficit/Hyperactivity Disorder (ADHD) is a topic of lively debate. The heterogeneity associated with ADHD and autism is described as falling on various continua of behavioural, neural, and genetic difference. These continua are varyingly described either as extending into the general population, or as being continua within a given disorder demarcation. Moreover, the interrelationships of these continua are likewise often vague and subject to diverse (...)
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  50. (1 other version)Genetic Determinism and the Innate-Acquired Distinction in Medicine.Maria E. Kronfeldner - 2009 - Medicine Studies (2):167-181.
    This article illustrates in which sense genetic determinism is still part of the contemporary interactionist consensus in medicine. Three dimensions of this consensus are discussed: kinds of causes, a continuum of traits ranging from monogenetic diseases to car accidents, and different kinds of determination due to different norms of reaction. On this basis, this article explicates in which sense the interactionist consensus presupposes the innate?acquired distinction. After a descriptive Part 1, Part 2 reviews why the innate?acquired distinction is under (...)
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