How should governments balance saving people from very large individual disease burdens (such as an early death) against saving them from middling burdens (such as erectile dysfunction) and minor burdens (such as nail fungus)? This chapter considers this question through an analysis of a priority-setting proposal in the Netherlands, on which avoiding a multitude of middling burdens takes priority over saving one person from early death, but no number of very small burdens can take priority over avoiding one death. It (...) argues that there is some, albeit imperfect, evidence of substantial public support for such a policy. Furthermore, it provides a principled rationale for it in terms of respect for the person who faces the largest burden. (shrink)

This chapter is centered around an apparent tension that research on implicit bias raises between virtue and social knowledge. Research suggests that simply knowing what the prevalent stereotypes are leads individuals to act in prejudiced ways—biasing decisions about whom to trust and whom to ignore, whom to promote and whom to imprison—even if they reflectively reject those stereotypes. Because efforts to combat discrimination obviously depend on knowledge of stereotypes, a question arises about what to do next. This chapter argues that (...) the obstacle to virtue is not knowledge of stereotypes as such, but the “accessibility” of such knowledge to the agent who has it. “Accessibility” refers to how easily knowledge comes to mind. Social agents can acquire the requisite knowledge of stereotypes while resisting their pernicious influence, so long as that knowledge remains, in relevant contexts, relatively inaccessible. (shrink)

Adverbialist theories of thought such as those advanced by Hare and Sellars promise an ontologically sleek understanding of a variety of intentional states, but such theories have been largely abandoned due to the ‘many-property problem’. In an attempt to revitalize this otherwise attractive theory, in a series of papers as well as his recent book, Uriah Kriegel has offered a novel reply to the ‘many-property problem’ and on its basis he argues that ‘adverbialism about intentionality is alive and well’. If (...) true, Kriegel will have shown that the logical landscape has long been unnecessarily constrained. His key idea is that the many-property problem can be overcome by appreciating that mental states stand in the determinable–determinate relation to one another. The present paper shows that this relation can’t save adverbialism because it would require thinkers to think more thoughts than they need be thinking. (shrink)

For a long time many philosophers felt the incoherence objection was a decisive objection to rule-consequentialism, but that position has recently become less secure, because Brad Hooker has offered a clever new way for rule-consequentialists to avoid the incoherence objection. Hooker’s response defeats traditional forms of the incoherence objection, but this paper argues that another version of the problem remains. Several possible solutions fail. One other does not, but it introduces other problems into the theory. I conclude that the (...) new incoherence objection still poses a major challenge to rule-consequentialism, though not for the reasons usually assumed. It does not constitute a fatal objection to rule-consequentialism but instead highlights a theoretical drawback in the theory which must be taken into account during a more holistic evaluation of rule-consequentialism and its rivals. (shrink)

How should sport deal with prematurely ended seasons? This question is especially relevant to the current COVID-19 inter- ruption that threatens to leave many leagues without cham- pions. We argue that although there can be no winners, in certain situations there should be champions. Relevant to the current situation, we argue that Liverpool FC—currently with a 22+ point lead—should be crowned champions of the English Premier League. However, things are not as simple as simply handing the championship to whoever was (...) in the lead when a season is prematurely ended. Through analogy with a fictional decathlon competition—and with the understanding that sporting seasons are themselves a type of game—we identify three reasons why leading at the moment of cessation is insufficient to be crowned a victor (of an individual event) or a champion (of a season-long competition): doing so fails to respect some valuable skills, fails to allow for luck to play out in an interesting way that affects competitions, and fails to respect competitive strategies. This discussion can then inform determining what, if any, end-of-season accolades are relevant, such as championships, relegation, or promotion. No team can win in a league that has failed to be completed, but there can still be a champion. (shrink)

Praised for its reliance on observation rather than myth, the Milesian school signals the dawn of science in the West. Whereas Hesiod appeals to the long ago and far away to explain the here and now, Thales and his cohorts do the reverse. In this reversal, we are their thankful, even faithful heirs. But with Hesiod not everything is myth and hearsay. Indeed, Hesiod singles himself out by name as the bearer of a powerfully poetic and distinctly human wisdom (...) that he consistently contrasts with Zeus’ divine wisdom. In this article, the author argues that the Milesians attempt to gain access to divine wisdom, and thus disregard the ambiguities characteristic of human wisdom. One sees this especially in a tension between Thales’ political wisdom and natural philosophy, and later between Anaximander’s cosmology and cosmogony. The author concludes that Heraclitus appears to have been the first thinker to confront the Hesiodic worldview on its own terms, inasmuch as his attempt to bridge the divide between divine and human wisdom always keeps one eye on the ambiguities that pervade human experience. (shrink)

In his two chief works, the Theogony and Works and Days, Hesiod treats the possibility of providence. In the former poem, he considers what sort of god could claim to gives human beings guidance. After arriving at Zeus as the only consistent possibility, Hesiod presents Zeus’ rule as both cosmic and legalistic. In the latter poem, how- ever, Hesiod shows that so long as Zeus is legalistic, his rule is limited cosmically to the human being. Ultimately, Zeus’ rule emerges (...) as more human than cosmic, and thus unable to fulfill the cosmic demands of piety. Hesiod’s presentation thus begs, without thematically posing, the question of how human beings ought to live. Accordingly, Hesiod’s theological analysis, and not his theogony (or, implicit cosmogony or cosmology), sets the stage for the inquiries of the early Greek philosophers, and so political philosophy as a whole. (shrink)

Part of the draw of athletics is its straightforwardness. There are nuances to competitions to make them more sporting contests, but at the end of a long jump competition whomever records the longest jump should win. Unfortunately, a recent rule-change at the highest level of the sport – the “Final 3” format – undermined this simplicity for the horizontal jumps and the throws for some of the 2020 and much of the 2021 seasons. While fortunately this rule was largely (...) reverted within days of the initial submission of this paper, it’s still valuable to critically evaluate why such a rule is problematic so as to better understand of the value of sporting competitions and give guidance on future rule changes, be they in athletics or other sports. To that end, we will be drawing from the literature on the purpose and value of competitions and coupling that with simulations based on data from actual top-tier long jump competitions to show that the Final 3 format makes for significantly worse competitions than the standard format. (shrink)

In the late 19th century Husserl studied our internal sense of time passing, maintaining that its deep connections into experience represent prima facie evidence for it as the basis for all investigations in the sciences: Phenomenology was born. Merleau-Ponty focused on perception pointing out that any theory of experience must in accord with established aspects of biology i.e. embodied. Recent analyses suggest that theories of experience require non-reductive, integrative information, together with a specific property connecting them to experience. Here we (...) elucidate a new class of information states with just such properties found at the loci of control of complex biological systems, including nervous systems. Complexity biology concerns states satisfying self-organized criticality. Such states are located at critical instabilities, commonly observed in biological systems, and thought to maximize information diversity and processing, and hence to optimize regulation. Major results for biology follow: why organisms have unusually low entropies; and why they are not merely mechanical. Criticality states form singular self-observing systems, which reduce wave packets by processes of perfect self-observation associated with feedback gain g=1. Analysis of their information properties leads to identification of a new kind of information state with high levels of internal coherence, and feedback loops integrated into their structure. The major idea presented here is that the integrated feedback loops are responsible for our ‘sense of self’, and also the feeling of continuity in our sense of time passing. Long-range internal correlations guarantee a unique kind of non-reductive, integrative information structure enabling such states to naturally support phenomenal experience. Being founded in complexity biology, they are ‘embodied’; they also fulfill the statement that ‘The self is a process’, a singular process. High internal correlations and RenéThom-style catastrophes support non-digital forms of information, gestalt cognition, and information transfer via quantum teleportation. Criticality in complexity biology can ‘embody’ cognitive states supporting gestalts, and phenomenology’s senses of ‘self,’ time passing, existence and being. (shrink)

Comment on Beeghly, Erin. 2021. “Stereotyping as Discrimination: Why Thoughts Can Be Discriminatory.” Social Epistemology 35 (6): 547–63. -/- Beeghly’s “Stereotyping as Discrimination” is—characteristically—clear, thorough, and persuasive, rich with incisive arguments and thought-provoking case studies. In defending the view that stereotyping often constitutes discrimination, she makes a powerful case that, “Living ethically means cultivating a certain kind of ‘inner’ life and avoiding pernicious habits of thought, no matter how culturally pervasive” (Beeghly 2021b, 13). Support for such claims is traced back (...) not just to Aristotle and the Ten Commandments (Beeghly 2021b, 10), but also to critical social traditions. “As feminists and theorists of race have long noted, the most intimate aspects of our selves, including our ways of thinking, agency, and modes of embodiment, are among the mechanisms of group oppression” (Beeghly 2021b, 13). I offer, first, a tiny friendly amendment to one brief passage, followed by invitations to explore some of the further potential implications of Beeghly’s central theses. (shrink)

Social space is superimposed on the civilization map of the world whereas the social time is correlated with the duration of civilization existence. Within own civilization the concept space is non-homogeneous, there are “singled out points” — “concept factories”. As social structures, cities may exist rather long, sometimes during several millennia, but as concept centres they are limited by the duration of civilization existence. If civilization is a “concept universe”, nobody and nothing may cross the boundaries, which include cities (...) as well. Death of civilization leads to reboot cultural and historical space-time. On the other hand, reformatted olds concepts are not preserved, but there may be reception of old concepts and their new interpretation. However, even in case of genetic links presence, they are the other concepts and not modified old ones. Under certain circumstances may take place “rebranding” when attractive name is connected to the concept of absolutely different order to attach to it authority of the past. (shrink)

A rapidly growing body of scholarship embraces virtue jurisprudence, a series of (often ad hoc) attempts to incorporate the philosophical tradition of virtue ethics into legal theory. Broadly understood, virtue ethics describes an approach to moral questions that emphasizes the importance of developing and embodying various virtues, often as manifestations of human flourishing. Scholars typically contrast virtue ethics with deontological and consequentialist moral theories, tracing virtue-centered analysis to ancient Greek philosophers, and in particular to Aristotle. Virtue ethics has experienced a (...) revival over the past 65 years; but, long before that, it proved especially influential in Catholic moral thought, particularly through the work of Aquinas. Perhaps relatedly, scholars have seized on virtue jurisprudence to defend a range of politically conservative positions, such as originalist constitutional interpretation and the propriety of utilizing the law to regulate ostensibly “private” immoralities. This Article reveals the radically underappreciated progressive promise of virtue jurisprudence. Virtue jurisprudence requires no religious commitments whatsoever, but a strong version entails acceptance of the moral significance of developing one’s character—both within and without the law. On a compelling understanding of the virtues, rejecting a state of perpetual disadvantage under the law is a meaningful marker of the virtue of self-respect, and a repudiation of the vice of servility that would otherwise be imposed by the legal system itself. Thus, contrary to the predominant tenor of research on the subject, virtue jurisprudence can ground significant resistance to—and even defiance of—the law. In making this argument, the Article also draws novel connections between virtue jurisprudence and literature on (inter alia) race, feminism, and sexual orientation to reveal the unnoticed potential of virtue jurisprudence to push forward work in those and related areas. At a time when massive and widespread protests across the United States reflect a groundswell of support for overturning certain long-standing, legally-ingrained, systemic disadvantages of people of color, many might be surprised to learn that virtue jurisprudence can serve as a potent theoretical ally. (shrink)

The National Collegiate Athletic Association (NCAA) positions itself as an institution primarily dedicated to the health and betterment of “student-athletes” across the country, but in reality it is not so virtuous. This paper will show how decisions made during the COVID-19 pandemic of 2020 undermine the stated purpose of the current intercollegiate sports model in the United States. It will begin by presenting the claimed goals and values of the NCAA. Then, it will show how many decisions made during the (...) COVID-19 pandemic of 2020 are incompatible with these goals. In doing so, it will illustrate that there is one purpose that is far more in line with decisions during the 2020 pandemic: revenue generation through mass entertainment. Even for those who have long bought into the NCAA’s noble rhetoric, COVID-19 is mask off for the NCAA’s “collegiate model” myth. (shrink)

Driven by technological innovations, newborn screening (NBS) panels have been expanded and the development of genomic NBS pilot programs is rapidly progressing. Decisions on disease selection for NBS are still based on the Wilson and Jungner (WJ) criteria published in 1968. Despite this uniform reference, interpretation of the WJ criteria and actual disease selection for NBS programs are highly variable. A systematic literature search [PubMED search “Wilson” AND “Jungner”; last search 16.07.22] was performed to evaluate the applicability of the WJ (...) criteria for current and future NBS programs and the need for adaptation. By at least two reviewers, 105 publications (systematic literature search, N = 77; manual search, N = 28) were screened for relevant content and, finally, 38 publications were evaluated. Limited by the study design of qualitative text analysis, no statistical evaluation was performed, but a structured collection of reported aspects of criticism and proposed improvements was instead collated. This revealed a set of general limitations of the WJ criteria, such as imprecise terminology, lack of measurability and objectivity, missing pediatric focus, and absent guidance on program management. Furthermore, it unraveled specific aspects of criticism on clinical, diagnostic, therapeutic, and economical aspects. A major obstacle was found to be the incompletely understood natural history and phenotypic diversity of rare diseases prior to NBS implementation, resulting in uncertainty about case definition, risk stratification, and indications for treatment. This gap could be closed through the systematic collection and evaluation of real-world evidence on the quality, safety, and (cost-)effectiveness of NBS, as well as the long-term benefits experienced by screened individuals. An integrated NBS public health program that is designed to continuously learn would fulfil these requirements, and a multi-dimensional framework for future NBS programs integrating medical, ethical, legal, and societal perspectives is overdue. (shrink)

Based on a review of several “anomalies” in research using implicit measures, Machery (2021) dismisses the modal interpretation of participant responses on implicit measures and, by extension, the value of implicit measures. We argue that the reviewed findings are anomalies only for specific—influential but long-contested—accounts that treat responses on implicit measures as uncontaminated indicators of trait-like unconscious representations that coexist with functionally independent conscious representations. However, the reviewed findings are to-be-expected “normalities” when viewed from the perspective of long-standing (...) alternative frameworks that treat responses on implicit measures as the product of dynamic processes that operate on momentarily activated, consciously accessible information. Thus, although we agree with Machery that the modal view is empirically unsupported, we argue that implicit measures can make a valuable contribution to understanding the complexities of human behavior if they are used wisely in a way that acknowledges what they can and cannot do. (shrink)

The first part of a symposium devoted to Alex Broadbent's essay titled ‘Prediction, Understanding and Medicine’, this article notes the under-development of a variety of issues in the philosophy of medicine that transcend bioethics and the long-standing debates about the nature of health/illness and of evidence-based medicine. It also indicates the importance of drawing on non-Western, and particularly African, traditions in addressing these largely metaphysical and epistemological matters.

Bence Nanay has argued that we must abandon the etiological theory of teleological function because this theory explains functions and functional categories in a circular manner. Paul Griffiths argued earlier that we should retain the etiological theory and instead prevent the circularity by making etiologies independent of functional categories. Karen Neander and Alex Rosenberg reply to Nanay similarly, and argue that we should analyze functions in terms of natural selection acting not on functional categories, but merely on lineages. Nanay (...) replies that these lineages cannot be individuated except by reference to functional categories. Worryingly, Neander and Rosenberg themselves have previously argued persuasively that homology often depends on function. This article addresses their arguments and shows how to escape them: Regardless whether the arguments are right about long-term homological categories, they do not apply to generation-to-generation homology. The latter, moreover, is sufficient for individuating the lineages needed to explain teleological functions. (shrink)

In November 2003, the University of Fribourg hosted a symposium on the ontology of colors. The invited participants included Justin Broackes, Alex Byrne, David Chalmers, Larry Hardin, Joe Levine and Barry Maund. The points of view presented by the participants in their thought-provoking papers were highly divergent. The presentation of each paper was followed by a long and intense discussion. Despite the divergence of the views proposed, the discussion during the symposium was highly focused. Several specific issues came (...) up repeatedly in the debate and illuminated the puzzle about the nature of colors in a thought provoking way from different angles. We include these papers in our brief description in the present introduction to present to the reader all the different viewpoints that have nourished the debate throughout the symposium. We are glad to be able to include one further invited paper by Jonathan Cohen in the present volume. In an attempt to transfer some of the atmosphere of the meeting to the reader and in order to make this collection still more stimulating we invited each participant to contribute comments on the other papers. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE A METRITE EM VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__3. METRITE -/- O transtorno caracterizado pela inflamação do útero, devido a causas sépticas ou assépticas que atuam sobre ele, denomina-se genericamente como metrite. As metrites são afecções de grande importância, tanto pela frequência como pela gravidade. As metrites podem ser divididas segundo seu caráter anatômico, como mucosa (catarral), purulenta, hemorrágica, crupal, (...) pútrida e flegmonosa e segundo seu curso, em agudas e crônicas (FRAZER, 2005; GORDON, 1996). Estão associadas às doenças do puerpério. Quando a inflamação é limitada à mucosa é chamada de endometrite; e se ademais interessa a camada muscular denomina-se metrite ou miometrite; se afeta o revestimento peritoneal, perimetrite ou metroperitonite; e se a inflamação se estende ao paramétrio, ou seja, ao tecido conjuntivo pélvico e ligamentos, chama-se parametrite (FÖLDI, et al. 2006). A metrite ocorre em consequência de diversos acidentes que resultam de partos distócicos, após retenção fetal ou secundinas seguidas de putrefação, por arrancamento brutal dos cotilédones; por injeções uterinas irritantes; após o prolapso uterino; tudo o que favorece o desenvolvimento microbiano. Em fêmeas que se inseminam artificialmente sob condições sépticas ou de pobre destreza se produz endometrite seguida com infecundidade passageira, isto se produz como consequência das erosões produzidas pela pistola de inseminação, desassossego geral no procedimento ou por levar o sêmen a maior temperatura que a devida e em lugar inadequado. Algumas situações de origem nutricional se associam em maior ou menor grau com a incidência de metrite, em especial processos de retenção de placenta ou involução uterina de origem nutricional podem levar, de forma indireta, a incidência de metrite. 3.1 Relação energia e proteína Uma das situações de origem nutricional associada à metrite é o excesso de proteína crua na dieta. As vacas necessitam de um adequado fornecimento de proteína. No afã de suprir as necessidades nutricionais e evitar as limitações de aminoácidos, cai-se no erro de fornecer excessos de proteína, trazendo como consequência uma diminuição da eficiência reprodutiva, devido à relação dos altos níveis de proteína na dieta com a falha reprodutiva específica. Um excesso de proteína resulta num aumento da produção de amoníaco e, como consequência, numa maior síntese de ureia pelo fígado (BACH, 2000). Consequentemente, existe um aumento do nível de ureia no sangue, no útero e no muco vaginal. A nível uterino, a ureia parece ter um efeito sobre a função hormonal e depressora da proteção imunitária. O mecanismo específico baseia-se na toxicidade direta da ureia, na perda do balanço energético e na concentração de diaminas de ácido carbônico que favorecem a ampla difusão da ureia em todo o endométrio. O fornecimento de fontes alternativas de nitrogênio na alimentação dos animais vêm ganhando espaço no debate entre os especialista e a ureia é uma dessas fontes. Ela é conhecida como uma fonte de nitrogênio não-proteico (NNP), porém não se destaca tanto pelos inúmeros fatores negativos como a baixa aceitabilidade dos animais ou aos índices de intoxicação pela mesma. O rúmen necessita de um teor de 1% de nitrogênio para manter os mecanismos fisiológicos e a população microbiana, sendo assim, o produtor deve estar atento ao fornecimento desse mineral para seus animais. Especialistas apontam a fórmula de 30 g de ureia por dia para animais de 100 kg, e que essa quantidade nunca pode exceder os 200 g por animal por dia. Esses dados só podem ser postos em prática se as forrageiras existentes na propriedade não conseguirem suprir a exigência de 1% de nitrogênio no animal. Uma fonte vegetal de ótima qualidade e abundante em meios nutricionais e fonte extra de renda é a cana-de-açúcar. Ao nível hormonal a presença de ureia impede a manutenção do gradiente de pH (induzido pela progesterona) que existe entre as células apicais e basais da parede uterina (MARÍN & CÁRDENAS, 1999). Assim, a progesterona não consegue manter o gradiente de pH e aumenta a secreção de PGF2α, que afeta negativamente tanto a sobrevivência como o desenvolvimento embrionário. A nível imunológico, ocorre um efeito negativo devido à elevada concentração de amônio e ureia no sangue, o que diminui a atividade dos linfócitos e impede a defesa celular contra os agentes nocivos provocadores da metrite infecciosa, favorecendo o desenvolvimento microbiano. Para determinar a quantidade e a qualidade da nutrição proteica do animal são utilizados indicadores como a concentração de ureia no sangue e no leite. As proteínas, em geral, possuem inúmeras funções, dentre elas componentes estruturais, funções enzimáticas, funções hormonais, recepção de estímulos hormonais e armazenamento de informações genéticas. Na nutrição animal, as proteínas são divididas entre bruta (PB) e metabolizável (PM), ainda outras, mas o enfoque são essas. Os animais necessitam de níveis distintos de proteínas em suas respectivas fases de vida. Para elucidar melhor, tomemos como exemplo uma vaca nelore de 420 kg no final da gestação necessita, em média, de 389 g/dia de proteína metabolizável e, em média de 581 g/dia de proteína bruta. Os alimentos de origem vegetal (forrageiras) fornecem muito bem e eficazmente teores aceitáveis de proteínas, porém como o elemento mais presente é a fibra, faz-se necessário a suplementação nos animais, e um meio de suprir as necessidades dos mesmo, é optando por farelos de soja que possuem mais de 60% de proteína em sua composição, ou outras fontes alternativas como as farinhas de origem animal como a de sangue, por exemplo. A deficiência de fibra crua desencadeia principalmente uma deficiência de energia no ruminante; pois a partir da fibra formam-se os ácidos graxos voláteis (AGV) que constituem até 60% das fontes energéticas para estes animais. Devido à síntese reduzida de AGV, é muito baixa a concentração destes, são absorvidos pela corrente sanguínea e o animal entra em estado de déficit de precursores glicogênios. Como o consumo de alimento no pós-parto está reduzido, e não há a suficiente disposição de energia (deficiência de AGV principalmente ácido acético, devido a deficiência em fibra crua), o organismo realiza uma mobilização de ácidos graxos para a compensação energética. Os ácidos graxos são levados até acetil-CoA, este é convertido pelo fígado em corpos cetônicos que são utilizados em baixa concentração por alguns tecidos periféricos (cérebro) como fonte de energia, pois os excessos de corpos cetônicos produzem toxicidade. Os excessos de acetil-CoA no fígado podem sofrer condensação e converterem-se em β-hidroxi-β-metil-glutaril-CoA que serve como fonte de mevalonato (precursor do colesterol formado em excesso). Os excessos provocam fígado graxo que gera danos hepáticos, isso deprime a síntese de ácidos graxos para a formação do colesterol que se encontra diretamente implicado na síntese de estrogênios. Após o parto uma deficiência de estrogênio provoca de forma subsequente atonia uterina, retenção de placenta, endometrite puerperal e finalmente metrite. 3.2 Vitaminas Outra causa nutricional que incide na manifestação de metrite, é a vitamina A, que faz parte do grupo de vitaminas lipossolúveis e tem relevância especial na função reprodutiva. Esta exerce sua ação sobre a integridade estrutural e funcional das células epiteliais do organismo animal, atua sobre o crescimento, a reprodução e o desenvolvimento embrionário; mas seu papel principal é atuar como protetora dos epitélios, incluindo o endométrio. Além disso, tem um efeito estabilizador sobre várias membranas celulares e atua regulando a permeabilidade da membrana. A vitamina A, atua como estimuladora dos epitélios da mucosa tubária, uterina e vaginal, aumentando sua resistência contra os agentes infecciosos que produzem problemas que finalizam em metrite, também é necessária para as alterações histológicas que ocorrem na mucosa durante as diferentes fases do ciclo estral. Uma deficiência de vitamina A, pode causar morte embrionária, aborto, bezerros fracos ao nascimento e de forma subsequente uma retenção de placenta, (BACH, 2000) devido a não regulação da filtração de líquidos e gases através das membranas fetais; também dificulta a fecundação, devido à geração de uma atresia ovariana e à degeneração do epitélio germinal. Além disso, são produzidos edemas que ocasionam bezerros mortos ou prematuros (natimortos), o que provoca uma posterior retenção de placenta. Estas retenções provocam metaplasia queratinizam-te, dos epitélios da mucosa uterina-vaginal, o que provoca o aparecimento de metrite. Também, uma deficiência de outras vitaminas provocam o aparecimento de pequenas hemorragias, inchaço vulvar e degeneração epitelial das mucosas, em geral, isto provoca uma endometrite que posteriormente torna-se em metrite devido ao que se afeta a submucosa e a camada muscular do útero. Em relação ao pós-parto precoce, a capacidade de consumo de alimentos (forragem) é limitada, o que conduz, principalmente, a uma deficiência de fibras cruas na ruminação do animal, que conduzirá, em algumas circunstâncias, à predisposição para o desenvolvimento de metrite. Atentos a essas intempéries, o produtor deve estar atento aos requerimento exigidos pelos animais de vitaminas para que possam manter seu funcionamento normal e longe de quaisquer problema ou agente infeccioso ou patógeno. Para tanto, os níveis de vitaminas por categoria animal, deve prezar pelas quantidades conforme demonstrado nas tabelas abaixo: Tabela 1: Exigências de vitaminas por categoria animal em bovinos de corte -/- Categoria Vitamina A (UI/dia) Vitamina E (mg/dia) Vitamina D (UI/dia) Niacina (g/dia) Vacas lactantes 80.000 – 120.000 100 – 1.000 15.000 – 50.000 1 - 2 Vacas secas 75.000 – 125.000 500 – 900 10.000 – 20.000 0 – 1 Fonte: BERCHIELLI et al., 2006. Tabela 2: Exigências de vitaminas em vacas gestantes de corte -/- Vitamina UI/kg de MS A 2.800 D 275 Fonte: BERCHIELLI et al., 2006. Para que se consiga suprir todas essas quantidades requeridas dos animais, em especial, das vacas gestantes para que não venha a ocorrer a incidência de metrite ou outro transtorno reprodutivo, o criador poderá optar pela injeção direta de complexos vitamínicos e minerais mediante os inúmeros fármacos da indústria farmacêutica animal, ou poderá suprir essas necessidades fisiológicas mediante o fornecimento de rações com teores adequados de vitaminas, ou ainda por intermédio de alimentos volumosos que além das vitaminas necessárias fornecem também as fibras. As forrageiras, leguminosas e gramíneas fornecem minerais, fibras e vitaminas; dentre elas as espécies tifton (capim) apresenta cerca de 34,8% de vitamina A, o capim-tanzânia apresenta 24% e a alfafa 23,4%. Por fim, métodos para fornecimento de fibras, vitaminas e/ou minerais não faltam. Apoio -/- Realização •_ _referências bibliográficas -/- BACH, Alex; ESPAÑA, Purina. La reproducción del vacuno lechero: Nutrición y fisiología. XVII Curso de Especialización FEDNA. Purina, España, 2002. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. DA SILVA, Emanuel Isaque Cordeiro. Reprodução Animal: Fisiologia do Parto e da Lactação Animal. Disponível em:-. Acesso em: Março de 2020. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FÖLDI, J. et al. Bacterial complications of postpartum uterine involution in cattle. Animal reproduction science, v. 96, n. 3-4, p. 265-281, 2006. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. MARÍN, Andrés Luis Martínez; CÁRDENAS, Juan F. Sánchez. Alimentación y reproducción en vacas lecheras. MG Mundo ganadero, n. 111, p. 48-54, 1999. RÚGELES, Clara. Interrelaciones entre nutrición y fertilidad en bovinos. Revista MVZ Córdoba, p. 24-30, 2001. -/- Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020 . (shrink)

Research suggests that interventions involving extensive training or counterconditioning can reduce implicit prejudice and stereotyping, and even susceptibility to stereotype threat. This research is widely cited as providing an “existence proof” that certain entrenched social attitudes are capable of change, but is summarily dismissed—by philosophers, psychologists, and activists alike—as lacking direct, practical import for the broader struggle against prejudice, discrimination, and inequality. Criticisms of these “debiasing” procedures fall into three categories: concerns about empirical efficacy, about practical feasibility, and about the (...) failure to appreciate the underlying structural-institutional nature of discrimination. I reply to these criticisms of debiasing, and argue that a comprehensive strategy for combating prejudice and discrimination should include a central role for training our biases away. (shrink)

This paper investigates how inquiry into normative language can improve substantive normative theorizing. First I examine two dimensions along which normative language differs: “strength” and “subjectivity.” Next I show how greater sensitivity to these features of the meaning and use of normative language can illuminate debates about three issues in ethics: the coherence of moral dilemmas, the possibility of supererogatory acts, and the connection between making a normative judgment and being motivated to act accordingly. The paper concludes with several brief (...) reflections on the theoretical utility of the distinction—at least so-called—between “normative” and “non-normative” language and judgment. Clarifying the language we use in normative conversation and theorizing can help us diagnose problems with bad arguments and formulate better motivated questions. This can lead to clearer answers and bring into relief new theoretical possibilities and avenues to explore. (shrink)

Those who want to deny the ‘ought implies can’ principle often turn to weakened views to explain ‘ought implies can’ phenomena. The two most common versions of such views are that ‘ought’ presupposes ‘can’, and that ‘ought’ conversationally implicates ‘can’. This paper will reject both views, and in doing so, present a case against any pragmatic view of ‘ought implies can’. Unlike much of the literature, I won't rely on counterexamples, but instead will argue that each of these views fails (...) on its own terms. ‘Ought’ and ‘can’ do not obey the negation test for presupposition, and they do not obey the calculability or the cancelability tests for conversational implicature. I diagnose these failures as partly a result of the importance of the contrapositive of ‘ought implies can’. I end with a final argument emphasizing the role the principle plays in moral thinking, and the fact that no pragmatic account can do it justice. (shrink)

Many believe that we ought to save a large number from being permanently bedridden rather than save one from death. Many also believe that we ought to save one from death rather than a multitude from a very minor harm, no matter how large this multitude. I argue that a principle I call “Aggregate Relevant Claims” satisfactorily explains these judgments. I offer a rationale for this principle and defend it against objections.

In the last decade there has been a torrent of work at the intersection of philosophy and linguistics on predicates of personal taste, subjective expressions like fun and tasty that are used to express opinions rather than matters of fact. In each section of this paper I discuss a phenomenon that has been largely overlooked in the literature on PPTs. In Section 1, I identify a neglected experiential reading of these adjectives. All other theories of expressions like fun take them (...) to express some standing property, but distributional and compositional considerations suggest that the basic meaning of fun adjectives is experiential. In Section 2, I discuss the relation between fun claims relativized to particular experiencers and their unrelativized counterparts, arguing that previous theories fail to capture the evaluativity unique to the latter. Finally, I argue... (shrink)

According to telling based views of testimony (TBVs), B has reason to believe that p when A tells B that p because A thereby takes public responsibility for B's subsequent belief that p. Andrew Peet presents a new argument against TBVs. He argues that insofar as A uses context-sensitive expressions to express p, A doesn't take public responsibility for B's belief that p. Since context-sensitivity is widespread, the kind of reason TBVs say we have to believe what we're told, is (...) not widespread. Peet doesn't identify any problem with his own argument though he does attempt to limit its sceptical potential by identifying special contexts in which TBVs stand a chance of success. A more general defence of TBVs can be provided by showing Peet's argument to be unsound. I argue that Peet's argument is unsound because it requires us to wrongly suppose that speakers do far less labour than their audiences in context-sensitive linguistic communication. I aim to show why—in the context of the epistemology of testimony and the philosophy of language—it's important to recognize the labour that speakers can do, and so can can be held responsible for not doing, in episodes of context-sensitive linguistic communication. (shrink)

I begin the paper by outlining one classic argument for the guise of the good: that we must think that desires represent their objects favourably in order to explain why they can make actions rational (Quinn 1995; Stampe 1987). But what exactly is the conclusion of this argument? Many have recently formulated the guise of the good as the view that desires are akin to perceptual appearances of the good (Oddie 2005; Stampe 1987; Tenenbaum 2007). But I argue that this (...) view fails to capitalize on the above argument, and that the argument is better understood as favouring a view on which desires are belief-like states. I finish by addressing some countervailing claims made by Avery Archer (2016). (shrink)

An approach to implementing variational Bayesian inference in biological systems is considered, under which the thermodynamic free energy of a system directly encodes its variational free energy. In the case of the brain, this assumption places constraints on the neuronal encoding of generative and recognition densities, in particular requiring a stochastic population code. The resulting relationship between thermodynamic and variational free energies is prefigured in mind–brain identity theses in philosophy and in the Gestalt hypothesis of psychophysical isomorphism.

The present paper looks at one of the most thorough articles on the intelligence of GPT, research conducted by engineers at Microsoft. Although there is a great deal of value in their work, I will argue that, for familiar philosophical reasons, their methodology, ‘Black-box Interpretability’ is wrongheaded. But there is a better way. There is an exciting and emerging discipline of ‘Inner Interpretability’ (also sometimes called ‘White-box Interpretability’) that aims to uncover the internal activations and weights of models in order (...) to understand what they represent and the algorithms they implement. In my view, a crucial mistake in Black-box Interpretability is the failure to appreciate that how processes are carried out matters when it comes to intelligence and understanding. I can’t pretend to have a full story that provides both necessary and sufficient conditions for being intelligent, but I do think that Inner Interpretability dovetails nicely with plausible philosophical views of what intelligence requires. So the conclusion is modest, but the important point in my view is seeing how to get the research on the right track. Towards the end of the paper, I will show how some of the philosophical concepts can be used to further refine how Inner Interpretability is approached, so the paper helps draw out a profitable, future two-way exchange between Philosophers and Computer Scientists. (shrink)

This paper develops an account of mood selection with attitude predicates in French. I start by examining the “contextual commitment” account of mood developed by Portner and Rubinstein Proceedings of SALT 22, CLC Publications, Ithaca, NY, pp 461–487, 2012). A key innovation of Portner and Rubinstein’s account is to treat mood selection as fundamentally depending on a relation between individuals’ attitudes and the predicate’s modal backgrounds. I raise challenges for P&R’s qualitative analysis of contextual commitment and explanations of mood selection. (...) There are indicative-selecting predicates that are felicitous in contexts where there isn’t contextual commitment ; and there are subjunctive-selecting predicates that involve no less contextual commitment than certain indicative-selecting verbs. I develop an alternative account of verbal mood. The general approach, which I call a state-of-mind approach, is to analyze mood in terms of whether the formal relation between the predicate’s modal backgrounds and an overall state of mind represents a relation of commitment. Indicative mood in French presupposes that the informational-evaluative state determined by the predicate’s modal backgrounds is included in the informational-evaluative state characterizing the event described by the predicate. The account provides an improved explanation of core mood-selection puzzles, including subjunctive-selection with emotive factives, indicative-selection with fiction verbs, indicative-selection with espérer ‘hope’ versus subjunctive-selection with vouloir ‘want’, and indicative-selection with commissives versus subjunctive-selection with directives. Subjunctive-selection with modal adjectives is briefly considered. The mood-selection properties of the predicates are derived from the proposed analysis of mood, independently attested features of the predicates’ semantics, and general principles of interpretation. (shrink)

Several decades of work in both philosophy and psychology acutely highlights our limitations as individual inquirers. One way to recognize these limitations is to defer to experts: roughly, to form one’s beliefs on the basis of expert testimony. Yet, as has become salient in the age of Brexit, Trumpist politics, and climate change denial, people are often mistrustful of experts, and unwilling to defer to them. It’s a trope of highbrow public discourse that this unwillingness is a serious pathology. But (...) to what extent is this trope accurate? Answering this requires us to settle both a normative question—under exactly what conditions ought we to defer to experts?—and an empirical question—under what conditions are people willing to defer to experts? The first question has been investigated primarily by philosophers; the second, primarily by psychologists. Yet there is little work integrating these literatures and putting together their results. The aim of this review article is to begin this task, enabling us to begin reaching conclusions about how much real practices of deference diverge from the ideal. We present an opinionated guide to relevant work from both philosophy and psychology, and note places where the literature has important gaps. (shrink)

In 'Rethinking the Good', Larry Temkin makes two core claims. First, the goodness of a distribution is sometimes ‘essentially comparative’ – it sometimes depends on which alternative distribution(s) it is compared to. Second, such cases threaten the transitivity of ‘all things considered better than’. I argue that the goodness of a distribution may indeed depend on what other distributions are feasible. But contrary to Temkin, I also argue that transitivity holds even when the goodness of a distribution depends on the (...) feasible set of which it is a member. (shrink)

It's sometimes thought that context-invariant linguistic meaning must be a character (a function from context types to contents) i.e. that linguistic meaning must determine how the content of an expression is fixed in context. This is thought because if context-invariant linguistic meaning were not a character then communication would not be possible. In this paper, I explain how communication could proceed even if context-invariant linguistic meaning were not a character.

"It is difficult not to notice a curious unrest in the philosophic atmosphere of the time, a loosening of old landmarks, a softening of oppositions, a mutual borrowing from one another on the part of systems anciently closed, and an interest in new suggestions, however vague, as if the one thing sure were the inadequacy of extant school-solutions. The dissatisfactions with these seems due for the most part to a feeling that they are too abstract and academic. Life is confused (...) and superabundant, and what the younger generation appears to crave is more of the temperament of life in its philosophy, even though it were at some cost of logical rigor and formal purity." - William James (1904). -/- Abstract: The study of model-based reasoning (MBR) is one of the most interesting recent developments at the intersection of psychology and the philosophy of science. Although a broad and eclectic area of inquiry, one central axis by which MBR connects these disciplines is anchored at one end in theories of internal reasoning (in cognitive science), and at the other, in C.S. Peirce’s semiotics (in philosophy). In this paper, we attempt to show that Peirce’s semiotics actually has more natural affinity on the psychological side with ecological psychology, as originated by James J. Gibson and especially Egon Brunswik, than it does with non-interactionist approaches to cognitive science. In particular, we highlight the strong ties we believe to exist between the triarchic structure of semiotics as conceived by Peirce, and the similar triarchic stucture of Brunswik’s lens model of organismic achievement in irreducibly uncertain ecologies. The lens model, considered as a theory of creative abduction, provides a concrete instantiation of at least one, albeit limited, interpretation of Peirce’s semiotics, one that we believe could be quite fruitful in future theoretical and empirical investigations of MBR in both science an philosophy. (shrink)

Intentionality, or the power of minds to be about, to represent, or to stand for things, remains central in the philosophy of mind. But the study of intentionality in the analytic tradition has been dominated by discussions of propositional attitudes such as belief, desire, and visual perception. There are, however, intentional states that aren't obviously propositional attitudes. For example, Indiana Jones fears snakes, Antony loves Cleopatra, and Jane hates the monster under her bed. The present paper explores such mental states (...) in an introductory but opinionated way. (shrink)

This paper develops an account of the meaning of `ought', and the distinction between weak necessity modals (`ought', `should') and strong necessity modals (`must', `have to'). I argue that there is nothing specially ``strong'' about strong necessity modals per se: uses of `Must p' predicate the (deontic/epistemic/etc.) necessity of the prejacent p of the actual world (evaluation world). The apparent ``weakness'' of weak necessity modals derives from their bracketing whether the necessity of the prejacent is verified in the actual world. (...) `Ought p' can be accepted without needing to settle that the relevant considerations (norms, expectations, etc.) that actually apply verify the necessity of p. I call the basic account a modal-past approach to the weak/strong necessity modal distinction (for reasons that become evident). Several ways of implementing the approach in the formal semantics/pragmatics are critically examined. The account systematizes a wide range of linguistic phenomena: it generalizes across flavors of modality; it elucidates a special role that weak necessity modals play in discourse and planning; it captures contrasting logical, expressive, and illocutionary properties of weak and strong necessity modals; and it sheds light on how a notion of `ought' is often expressed in other languages. These phenomena have resisted systematic explanation. In closing I briefly consider how linguistic inquiry into differences among necessity modals may improve theorizing on broader philosophical issues. (shrink)

When people must either save a greater number of people from a smaller harm or a smaller number from a greater harm, do their choices reflect a reasonable moral outlook? We pursue this question with the help of an experiment. In our experiment, two-fifths of subjects employ a similarity heuristic. When alternatives appear dissimilar in terms of the number saved but similar in terms of the magnitude of harm prevented, this heuristic mandates saving the greater number. In our experiment, this (...) leads to choices that are inconsistent with all standard theories of justice. We argue that this demonstrates the untrustworthiness of distributive judgments in cases that elicit similarity-based choice. (shrink)

Are women (simply) adult human females? Dictionaries suggest that they are. However, philosophers who have explicitly considered the question invariably answer no. This paper argues that they are wrong. The orthodox view is that the category *woman* is a social category, like the categories *widow* and *police officer*, although exactly what this social category consists in is a matter of considerable disagreement. In any event, orthodoxy has it that *woman* is definitely not a biological category, like the categories *amphibian* or (...) *adult human female*. -/- In the first part, a number of arguments are given for the view that women are adult human females; the second part turns to rebutting the main objections. Finally, a couple of morals are briefly noted: one for activist sloganeering, and one for ameliorative projects that seek to change the meaning of ‘woman’. (shrink)

This paper demarcates a theoretically interesting class of "evaluational adjectives." This class includes predicates expressing various kinds of normative and epistemic evaluation, such as predicates of personal taste, aesthetic adjectives, moral adjectives, and epistemic adjectives, among others. Evaluational adjectives are distinguished, empirically, in exhibiting phenomena such as discourse-oriented use, felicitous embedding under the attitude verb `find', and sorites-susceptibility in the comparative form. A unified degree-based semantics is developed: What distinguishes evaluational adjectives, semantically, is that they denote context-dependent measure functions ("evaluational (...) perspectives")—context-dependent mappings to degrees of taste, beauty, probability, etc., depending on the adjective. This perspective-sensitivity characterizing the class of evaluational adjectives cannot be assimilated to vagueness, sensitivity to an experiencer argument, or multidimensionality; and it cannot be demarcated in terms of pretheoretic notions of subjectivity, common in the literature. I propose that certain diagnostics for "subjective" expressions be analyzed instead in terms of a precisely specified kind of discourse-oriented use of context-sensitive language. I close by applying the account to `find x PRED' ascriptions. (shrink)

Priority monism is the view that the cosmos is the only independent concrete object. The paper argues that, pace its proponents, Priority monism is in conflict with the dependence of any whole on any of its parts: if the cosmos does not depend on its parts, neither does any smaller composite.

Many philosophers and psychologists have attempted to elucidate the nature of mental representation by appealing to notions like isomorphism or abstract structural resemblance. The ‘structural representations’ that these theorists champion are said to count as representations by virtue of functioning as internal models of distal systems. In his 2007 book, Representation Reconsidered, William Ramsey endorses the structural conception of mental representation, but uses it to develop a novel argument against representationalism, the widespread view that cognition essentially involves the manipulation of (...) mental representations. Ramsey argues that although theories within the ‘classical’ tradition of cognitive science once posited structural representations, these theories are being superseded by newer theories, within the tradition of connectionism and cognitive neuroscience, which rarely if ever appeal to structural representations. Instead, these theories seem to be explaining cognition by invoking so-called ‘receptor representations’, which, Ramsey claims, aren’t genuine representations at all—despite being called representations, these mechanisms function more as triggers or causal relays than as genuine stand-ins for distal systems. I argue that when the notions of structural and receptor representation are properly explicated, there turns out to be no distinction between them. There only appears to be a distinction between receptor and structural representations because the latter are tacitly conflated with the ‘mental models’ ostensibly involved in offline cognitive processes such as episodic memory and mental imagery. While structural representations might count as genuine representations, they aren’t distinctively mental representations, for they can be found in all sorts of non-intentional systems such as plants. Thus to explain the kinds of offline cognitive capacities that have motivated talk of mental models, we must develop richer conceptions of mental representation than those provided by the notions of structural and receptor representation. (shrink)

This paper elaborates and defends a familiar ‘transparent’ account of knowledge of one's own beliefs, inspired by some remarks of Gareth Evans, and makes a case that the account can be extended to mental states in general, in particular to knowledge of one's intentions.

For Austin, Grice, and many others, undertaking a speech act like asserting or promising requires uttering something with a particular sense and reference in mind. We argue that the phenomenon of open-ended promises reveals this 'Locutionary Thesis' to be mistaken.

Discussions of aesthetic reasons and normativity are becoming increasingly popular. This piece outlines six basic questions about aesthetic reasons, normativity, and value and discusses the space of possible answers to these questions. I divide the terrain into two groups of three questions each. First are questions about the shape of aesthetic reasons: what they favour, how strong they are, and where they come from. Second are relational questions about how aesthetic reasons fit into the wider normative landscape: whether they are (...) distinctive, what their normative status is, and how they interact with each other and with non-aesthetic reasons. This piece aims to provide a taxonomy to clarify and organise the burgeoning literature and to make a few concrete suggestions for avenues of future research. (shrink)

The most famous Socratic question—ti esti touto?—is often pre- ceded by a far less famous, but more fundamental question—esti touto ti? Though this question is posed in many dialogues with re- spect to myriad topics, in every instance it receives but one answer: it is something, namely something that is. The dialogue devoted to why this question always meets with an affirmative answer would appear to be the Parmenides, for there Parmenides throws into question whether the eidē are, only to (...) establish that, if we have opinions that there is some unity in being, such unity must be. Nevertheless, the dramatic setting of the Parmenides is the quarreling of the Pre-Socratic schools, and the popular dismissal of philosophy that their quarreling engendered. For a dialogue that establishes that the object of inquiry is simply because we have opinions about it, we must, as I hope to show, turn to the Euthyphro. (shrink)

Excerpt: 1. Introduction This chapter provides insight into the diverse ethical debates on genetics and epigenetics. Much controversy surrounds debates about intervening into the germline genome of human embryos, with catchwords such as genome editing, designer baby, and CRISPR/Cas. The idea that it is possible to design a child according to one’s personal preferences is, however, a quite distorted view of what is actually possible with new gene technologies and gene therapies. These are much more limited than the editing and (...) design metaphors suggest. Such metaphors are therefore highly problematic phrases in the context of new gene technologies, for two reasons. On one hand, to design a child of choice by modifying the genome would require modifying any gene of choice, which is more than can be done with current gene technologies, such as CRISPR/Cas. On the other hand, a modification of genes would need to be enough to create any characteristic of choice in the future child. The latter presupposes the assumption of genetic determinism. Moreover, the CRISPR/Cas technology can not only be used in a potentially therapeutic manner at the germline level. In addition, there is the (more likely) scenario of a future clinical therapeutic use of these new gene technologies for modifying the DNA sequence of other cells of the body (somatic genome editing). There is also the option of modifying the epigenome, that is, the spatial configuration of DNA (epigenome editing) (see table 1). Like genetics and genome editing, epigenetics has been at the center of recent popular scientific and ethical discourse as well as scientific debates. The concept of epigenetics has given rise to very different notions of inheritability and responsibility for health, which, however, are oftentimes based on scientifically controversial basic assumptions. That there continues to be covert genetic determinism in the form of epigenetic determinism (see table 2) in debates about epigenetics has been pointed out in ethical analyses of epigenetics. Neither genetic determinism nor epigenetic determinism has been confirmed scientifically. It is therefore important to recognize the concepts that are discussed (and sometimes harshly criticized) in debates about genome editing and epigenetics—for example, concepts about the causal role of DNA for our own life course. This importance is based on the fact that if we understand such controversial concepts, we will be able to remain critical when evaluating scientific knowledge and ethical arguments about genome editing and epigenetics. This chapter, therefore, explains some of these concepts. For an ethical analysis of epigenetics as well as of genome editing, it is necessary to understand and critically reflect upon the underlying concepts of genetic determinism and other, related -isms. The following section offers a detailed introduction to these -isms (section 2; see also table 2). Section 3 provides an ethical analysis of genome editing and epigenetics based on the explanations in section 2. Section 3 focuses on inheritability and responsibility, justice, safety, the problem of consent, and the effects of genome editing and epigenetics on embryos and future generations. This section does not discuss in detail further points that can be found in ethical debates about epigenetics as well as in ethical debates about genome editing. These points include (among others): • fear that the findings of epigenetics and that the methods of genome editing are misused—this also with respect to eugenics and enhancement; • naturalness—an issue we mention in passing a few times in the following analysis; • a possible connection between the genome/epigenome and the concept of human dignity, and the derived danger of instrumentalization and infringement of autonomy when intervening in the genome or epigenome. Since current discourse about ethical issues associated with genome editing focuses mainly on germline interventions, which are, for instance, interventions into a human embryo’s genome, we mainly focus on germline interventions when comparing the debates on genome editing and on epigenetics in section 3. (shrink)

This paper presents a new objection to the buck-passing account of value. I distinguish the buck-passing account of predicative value from the buck-passing account of attributive value. According to the latter, facts about attributive value reduce to facts about reasons and their weights. But since facts about reasons’ weights are themselves facts about attributive value, this account presupposes what it is supposed to explain. As part of this argument, I also argue against Mark Schroeder's recent account of the weights of (...) reasons, which purports to explain the weights of reasons in terms of further reasons without circularity. I then argue that if we abandon the buck-passing account of attributive value, it would be ad hoc and unjustifiable to continue to endorse the buck-passing account of predicative value. In short, there seems to be little hope for the buck-passing account in either form. The paper ends by sketching a novel alternative theory according to which reasons are analysed in terms of the attributive value of motives. I suggest that a normative reason to is something that would be a good motive for -ing. At least at first glance, this view has numerous merits and few problems. (shrink)

Recent work on rationality has been increasingly attentive to “coherence requirements”, with heated debates about both the content of such requirements and their normative status (e.g., whether there is necessarily reason to comply with them). Yet there is little to no work on the metanormative status of coherence requirements. Metaphysically: what is it for two or more mental states to be jointly incoherent, such that they are banned by a coherence requirement? In virtue of what are some putative requirements genuine (...) and others not? Epistemologically: how are we to know which of the requirements are genuine and which aren’t? This paper tries to offer an account that answers these questions. On my account, the incoherence of a set of attitudinal mental states is a matter of its being (partially) constitutive of the mental states in question that, for any agent that holds these attitudes jointly, the agent is disposed, when conditions of full transparency are met, to give up at least one of the attitudes. (shrink)

In this paper, I argue that theories of perception that appeal to Helmholtz’s idea of unconscious inference (“Helmholtzian” theories) should be taken literally, i.e. that the inferences appealed to in such theories are inferences in the full sense of the term, as employed elsewhere in philosophy and in ordinary discourse. -/- In the course of the argument, I consider constraints on inference based on the idea that inference is a deliberate acton, and on the idea that inferences depend on the (...) syntactic structure of representations. I argue that inference is a personal-level but sometimes unconscious process that cannot in general be distinguished from association on the basis of the structures of the representations over which it’s defined. I also critique arguments against representationalist interpretations of Helmholtzian theories, and argue against the view that perceptual inference is encapsulated in a module. (shrink)

How do I know that I see a cat? A curiously under-asked question. The paper tries to answer it.

Critical discussion of Susanna Schellenberg's account of hallucination and perceptual evidence.