I here defend a theory consisting of four claims about ‘property’ and properties, and argue that they form a coherent whole that can solve various serious problems. The claims are (1): ‘property’ is defined by the principles (PR): ‘F-ness/Being F/etc. is a property of x iff F’ and (PA): ‘F-ness/Being F/etc. is a property’; (2) the function of ‘property’ is to increase the expressive power of English, roughly by mimicking quantification into predicate position; (3) property talk should be understood at (...) face value: apparent commitments are real and our apparently literal use of ‘property’ is really literal; (4) there are no properties. In virtue of (1)–(2), this is a deflationist theory and in virtue of (3)–(4), it is an error theory. (1) is fleshed out as a claim about understanding conditions, and it is argued at length, and by going through a number of examples, that it satisfies a crucial constraint on meaning claims: all facts about ‘property’ can be explained, together with auxiliary facts, on its basis. Once claim (1) has been expanded upon, I argue that the combination of (1)–(3) provides the means for handling several problems: they help giving a happy-face solution to what I call the paradox of abstraction , they form part of a plausible account of the correctness of committive sentences, and, most importantly, they help respond to various indispensability arguments against nominalism. (shrink)

A new kind of defense of the Millian theory of names is given, which explains intuitive counter-examples as depending on pragmatic effects of the relevant sentences, by direct application of Grice’s and Sperber and Wilson’s Relevance Theory and uncontroversial assumptions. I begin by arguing that synonyms are always intersubstitutable, despite Mates’ considerations, and then apply the method to names. Then, a fairly large sample of cases concerning names are dealt with in related ways. It is argued that the method, as (...) applied to the various cases, satisfies the criterion of success: that for every sentence in context, it is a counter-example to Millianism to the extent that it has pragmatic effects (matching speakers’ intuitions). (shrink)

Easy Ontology (EO), defended in several recent works by Amie Thomasson, and based on Carnap’s famous deflationism about metaphysics, is the view that many ontological questions, like ‘Are there numbers?’, are at bottom easy, at least when taken in their “internal” sense. Both Carnap and Thomasson take for granted that serious metaphysicians therefore cannot plausibly be interpreted as asking internal questions. Thus, they think they are committed to finding some alternative, special interpretation of metaphysicians’ utterances. I argue that none of (...) the alternative interpretations proposed in the literature are viable. More importantly, I argue that Carnap and Thomasson are wrong about this commitment. EO should instead be coupled with the view that metaphysicians ask internal questions, yet have the false belief that they can be answered only through metaphysical speculation. This is a significant modification of EO, in which the notion of an “external question” plays no role, and which results in a simpler and more plausible theory. (shrink)

Thomas Hofweber takes the semantic paradoxes to motivate a radical reconceptualization of logical validity, rejecting the idea that an inference rule is valid just in case every instance thereof is necessarily truth-preserving. Rather than this “strict validity”, we should identify validity with “generic validity”, where a rule is generically valid just in case its instances are truth preserving, and where this last sentence is a generic, like “Bears are dangerous”. While sympathetic to Hofweber’s view that strict validity should be replaced (...) by something allowing for exceptions, I argue that this should instead be truth-conduciveness, a matter of a large majority of instances being truth-preserving. The fact that inference rules have uncountably many instances, I argue, can be handled by defining truth-conduciveness as relative to finite sets of instances. Moreover, I argue that Hofweber’s position, while seemingly radical, may be less so under closer scrutiny. For the mere claim that classical rules and unrestricted truth rules are generically valid (or truth-conducive) is not in itself controversial. Also, if there is an answer to the question of which of these are also strictly valid, then the claim that generic validity is the central notion in logic is at most an interest-relative matter, since there is then also a fact of the matter as to which inference rules are (not) strictly valid. If no solution operating with strict validity to the paradoxes can be had, however, then the claim that validity should be identified with a weaker notion is better motivated. I argue that it is reasonable, in view of past failures, to conjecture that no ordinary solution will score high enough relative to standard (uncontroversial) desiderata to merit justified belief. Hence, it is unknowable which solution is correct. I further argue that this is best explained by its being metaphysically indeterminate which solution is correct. If this conjecture is true, then we ought instead to think of validity as allowing exceptions, and then take the “true logic” to be one that takes both the classical rules and the truth rules to be valid, i.e., truth-conducive. This logic scores very high on the desiderata on logics, and is therefore preferable to any logic operating with strict validity. (shrink)

I begin with an exposition of the two main variants of the Prosentential Theory of Truth (PT), those of Dorothy Grover et al. and Robert Brandom. Three main types of criticisms are then put forward: (1) material criticisms to the effect that (PT) does not adequately explain the linguistic data, (2) an objection to the effect that no variant of (PT) gives a properly unified account of the various occurrences of "true" in English, and, most importantly, (3) a charge that (...) the comparison with proforms is explanatorily idle. The last objection is that, given a complete semantic account of pronouns, proadjectives, antecedents, etc., together with a complete (PT), the essential semantic character of "true" could be deduced, but then, the idleness of the comparison with pronouns would be apparent. It turns out that objections (2) and (3) are related in the following way: the prosentential terminology is held to conceal the lack of unity in (PT), by describing the different data in the same terms ("proform", "antecedent", etc.). But this, I argue, is only a way of truly describing, rather than explaining, the data, these being certain relations of equivalence and consequence between sentences. I consider a language for which (PT) would be not only true, but also explanatory, but note that this language is very different from English. I end by showing that Robert Brandom's case that "is true" is not a predicate fails, and that his motivation for saying so is based on fallacious reasoning (namely, Boghossian's argument against deflationism). (shrink)

It is argued that although George Bealer's influential ‘Self-Consciousness argument’ refutes standard versions of reductive functionalism (RF), it fails to generalize in the way Bealer supposes. To wit, he presupposes that any version of RF must take the content of ‘pain’ to be the property of being in pain (and so on), which is expressly rejected in independently motivated versions of conceptual role semantics (CRS). Accordingly, there are independently motivated versions of RF, incorporating CRS, which avoid Bealer's main type of (...) refutation. I focus particularly on one such theory, which takes concepts to be event types that are individuated by their psychological roles, which has the resources of responding to each of the more specific worries Bealer expresses. (shrink)

The article first rehearses three deflationary theories of reference, (1) disquotationalism, (2) propositionalism (Horwich), and (3) the anaphoric theory (Brandom), and raises a number of objections against them. It turns out that each corresponds to a closely related theory of truth, and that these are subject to analogous criticisms to a surprisingly high extent. I then present a theory of my own, according to which the schema “That S(t) is about t” and the biconditional “S refers to x iff S (...) says something about x” are exhaustive of the notions of aboutness and reference. An account of the usefulness of “about” is then given, which, I argue, is superior to that of Horwich. I close with a few considerations about how the advertised theory relates to well-known issues of reference, the conclusions of which is (1) that the issues concern reference and aboutness only insofar as the words “about” and “refer” serve to generalise over the claims that are really at issue, (2) that the theory of reference will not settle the issues, and (3) that it follows from (2) that the issues do not concern the nature of aboutness or reference. (shrink)

Nominalists need some account of correctness for sentences committed to the existence of abstract objects. This paper proposes a new statement of such conditions specifically for properties. The account builds on an earlier proposal of mine, but avoids the counter-examples against the latter pointed out by Thomas Schindler, particularly, the sentence ‘There are inexpressible properties’. I argue that the new proposal is independently motivated and more faithful to the spirit of the kind of error-theoretic nominalism that the original proposal was (...) part of. Along the way, I also propose novel treatments of Arthur Pap’s and W.V.O. Quine’s notoriously hard-to-paraphrase sentences about abstracta. (shrink)

I here argue that Ted Sider's indeterminacy argument against vagueness in quantifiers fails. Sider claims that vagueness entails precisifications, but holds that precisifications of quantifiers cannot be coherently described: they will either deliver the wrong logical form to quantified sentences, or involve a presupposition that contradicts the claim that the quantifier is vague. Assuming (as does Sider) that the “connectedness” of objects can be precisely defined, I present a counter-example to Sider's contention, consisting of a partial, implicit definition of the (...) existential quantifier that in effect sets a given degree of connectedness among the putative parts of an object as a condition upon there being something (in the sense in question) with those parts. I then argue that such an implicit definition, taken together with an “auxiliary logic” (e.g., introduction and elimination rules), proves to function as a precisification in just the same way as paradigmatic precisifications of, e.g., “red”. I also argue that with a quantifier that is stipulated as maximally tolerant as to what mereological sums there are, precisifications can be given in the form of truth-conditions of quantified sentences, rather than by implicit definition. (shrink)

The paper discusses what kind of truth bearer, or truth-ascription, a deflationist should take as primary. I first present number of arguments against a sententialist view. I then present a deflationary theory which takes propositions as primary, and try to show that it deals neatly with a wide range of linguistic data. Next, I consider both the view that there is no primary truth bearer, and the most common account of sentence truth given by deflationists who take propositions as primary, (...) and argue that they both attribute an implausible type of ambiguity to “true”. This can be avoided, however, if truth-ascriptions to sentences are taken as a certain form of pragmatic ellipses. I end by showing how this hypothesis accommodates a number of intuitions involving truth-ascriptions to sentences. (shrink)

I here develop a specific version of the deflationary theory of truth. I adopt a terminology on which deflationism holds that an exhaustive account of truth is given by the equivalence between truth-ascriptions and de-nominalised (or disquoted) sentences. An adequate truth-theory, it is argued, must be finite, non-circular, and give a unified account of all occurrences of “true”. I also argue that it must descriptively capture the ordinary meaning of “true”, which is plausibly taken to be unambiguous. Ch. 2 is (...) a critical historical survey of deflationary theories, where notably disquotationalism is found untenable as a descriptive theory of “true”. In Ch. 3, I aim to show that deflationism cannot be finitely and non-circularly formulated by using “true”, and so must only mention it. Hence, it must be a theory specifically about the word “true” (and its foreign counterparts). To capture the ordinary notion, the theory must thus be an empirical, use-theoretic, semantic account of “true”. The task of explaining facts about truth now becomes that of showing that various sentences containing “true” are (unconditionally) assertible. In Ch. 4, I defend the claim (D) that every sentence of the form “That p is true” and the corresponding “p” are intersubstitutable (in a use-theoretic sense), and show how this claim provides a unified and simple account of a wide variety of occurrences of “true”. Disquotationalism then only has the advantage of avoiding propositions. But in Ch. 5, I note that (D) is not committed to propositions. Use-theoretic semantics is then argued to serve nominalism better than truth-theoretic ditto. In particular, it can avoid propositions while sustaining a natural syntactic treatment of “that”-clauses as singular terms and of “Everything he says is true”, as any other quantification. Finally, Horwich’s problem of deriving universal truth-claims is given a solution by recourse to an assertibilist semantics of the universal quantifier. (shrink)

I here propose a hitherto unnoticed possibility of solving embedding problems for noncognitivist expressivists in metaethics by appeal to Conceptual Role Semantics. I show that claims from the latter as to what constitutes various concepts can be used to define functions from states expressed by atomic sentences to states expressed by complex sentences, thereby allowing an expressivist semantics that satisfies a rather strict compositionality constraint. The proposal can be coupled with several different types of concept individuation claim, and is shown (...) to pave the way to novel accounts for, e.g., negation. (shrink)

The paper discusses the Inconsistency Theory of Truth (IT), the view that “true” is inconsistent in the sense that its meaning-constitutive principles include all instances of the truth-schema (T). It argues that (IT) entails that anyone using “true” in its ordinary sense is committed to all the (T)-instances and that any theory in which “true” is used in that sense entails the (T)-instances (which, given classical logic, entail contradictions). More specifically, I argue that theorists are committed to the meaning-constitutive principles (...) of logical constants, relative to the interpretation they intend thereof (e.g., classical), and that theories containing logical constants entail those principles. Further, I argue, since there is no relevant difference from the case of “true”, inconsistency theorists’ uses of “true” commit them to the (T)-instances. Adherents of (IT) are recommended, as a consequence, to eschew the truth-predicate. I also criticise Matti Eklund’s account of how the semantic value of “true” is determined, which can be taken as an attempt to show how “true” can be consistently used, despite being inconsistent. (shrink)

I here argue for a particular formulation of truth-deflationism, namely, the propositionally quantified formula, (Q) “For all p, <p> is true iff p”. The main argument consists of an enumeration of the other (five) possible formulations and criticisms thereof. Notably, Horwich’s Minimal Theory is found objectionable in that it cannot be accepted by finite beings. Other formulations err in not providing non-questionbegging, sufficiently direct derivations of the T-schema instances. I end by defending (Q) against various objections. In particular, I argue (...) that certain circularity charges rest on mistaken assumptions about logic that lead to Carroll’s regress. I show how the propositional quantifier can be seen as on a par with first-order quantifiers and so equally acceptable to use. While the proposed parallelism between these quantifiers is controversial in general, deflationists have special reasons to affirm it. I further argue that the main three types of approach the truth-paradoxes are open to an adherent of (Q), and that the derivation of general facts about truth can be explained on its basis. (shrink)

Semantic dispositionalism is roughly the view that meaning a certain thing by a word, or possessing a certain concept, consists in being disposed to do something, e.g., infer a certain way. Its main problem is that it seems to have so many and disparate exceptions. People can fail to infer as required due to lack of logical acumen, intoxication, confusion, deviant theories, neural malfunctioning, and so on. I present a theory stating possession conditions of concepts that are counterfactuals, rather than (...) disposition attributions, but which is otherwise similar to inferentialist versions of dispositionalism. I argue that it can handle all the exceptions discussed in the literature without recourse to ceteris paribus clauses. Psychological exceptions are handled by suitably undemanding requirements (unlike that of giving the sum of any two numbers) and by setting the following two preconditions upon someone’s making the inference: that she considers the inference and has no motivating reason against it. The non-psychological exceptions, i.e., cases of neural malfunctioning, are handled by requiring that the counterfactuals be true sufficiently often during the relevant interval. I argue that this accommodates some important intuitions about concept possession, in particular, the intuition that concept possession is vague along a certain dimension. (shrink)

I show that the act-type theories of Soames and Hanks entail that every sentence with alternative analyses (including every atomic sentence with a polyadic predicate) is ambiguous, many of them massively so. I assume that act types directed toward distinct objects are themselves distinct, plus some standard semantic axioms, and infer that act-type theorists are committed to saying that ‘Mary loves John’ expresses both the act type of predicating [loving John] of Mary and that of predicating [being loved by Mary] (...) of John. Since the two properties are distinct, so are the act types. Hence, the sentence expresses two propositions. I also discuss a non-standard “pluralist” act-type theory, as well as some retreat positions, which all come with considerable problems. Finally, I extrapolate to a general constraint on theories of structured propositions, and find that Jeffrey King’s theory has the same unacceptable consequence as the act-type theory. (shrink)

Deflationism about truth is often said to be incompatible with truth-theoretic semantics. However, both of these labels are ambiguous, making the truth of the incompatibility claim dependent on interpretation. I provide one pair of natural interpretations, on which both views relate essentially to grounding and on which they are indeed incompatible. This result has some intrinsic interest as well as paving the way for further needed clarifications in the debate about the relationship between the views.

The paper proposes a way for adherents of Fregean, structured propositions to designate propositions and other complex senses/concepts using a special kind of functor. I consider some formulations from Peacocke's works and highlight certain problems that arise as we try to quantify over propositional constituents while referring to propositions using "that"-clauses. With the functor notation, by contrast, we can quantify over senses/concepts with objectual, first-order quantifiers and speak without further ado about their involvement in propositions. The functor notation also turns (...) out to come with an important kind of expressive strengthening, and is shown to be neutral on several controversial issues. (shrink)

I here investigate whether there is any version of the principle of charity both strong enough to conflict with an error-theoretic version of nominalism (EN) about abstract objects, and supported by the considerations adduced in favour of interpretive charity in the literature. I argue that in order to be strong enough, the principle, which I call (Charity), would have to read, “For all expressions e, an acceptable interpretation must make true a sufficiently high ratio of accepted sentences containing e”. I (...) next consider arguments based on Davidson's intuitive cases for interpretive charity, the reliability of perceptual beliefs, and the reliability of “non-abstractive inference modes”, and conclude that none support (Charity). I then propose a diagnosis of the view that there must be some universal principle of charity ruling out (EN). Finally, I present a reason to think (Charity) is false, namely, that it seems to exclude the possibility of such disagreements as that between nominalists and realists. (shrink)

I here discuss two problems facing Russellian act-type theories of propositions, and argue that Fregean act-type theories are better equipped to deal with them. The first relates to complex singular terms like '2+2', which turn out not to pose any special problem for Fregeans at all, whereas Soames' theory currently has no satisfactory way of dealing with them (particularly, with such "mixed" propositions as the proposition that 2+2 is greater than 3). Admittedly, one possibility stands out as the most promising (...) one, but it requires that the Russellian treat complex properties as constituents of propositions. This leads to the second major problem for Russellians: that of proliferating propositions. I show how the most direct solution to this problem, that of rejecting complex predicative propositional constituents is available to Fregeans but very implausible for Russellians, since this virtually means rejecting complex properties. (shrink)

I here present and defend what I call the Triviality Theory of Truth, to be understood in analogy with Matti Eklund’s Inconsistency Theory of Truth. A specific formulation of is defended and compared with alternatives found in the literature. A number of objections against the proposed notion of meaning-constitutivity are discussed and held inconclusive. The main focus, however, is on the problem, discussed at length by Gupta and Belnap, that speakers do not accept epistemically neutral conclusions of Curry derivations. I (...) first argue that the facts about speakers’ reactions to such Curry derivations do not constitute a problem for the Triviality Theory specifically. Rather, they follow from independent, uncontroversial facts. I then propose a solution which coheres with the theory as I understand it. Finally, I consider a normative reading of their objection and offer a response. (shrink)

Although Benjamin Schnieder’s theory of the “ordinary conception” of properties successfully handles paradoxical properties—particularly, the property of non-self-instantiation—it fails to account for ordinary, non-pathological cases. The theory allows the inference of ‘a has the property of being F’ only given F(a) and the prior assertibility of ‘the property of being F can exist’. While this allows us to block an inference to a contradiction, it also blocks all of the non-pathological instances of the inference from ‘a is F’ to ‘a (...) has the property of being F’. It thereby fails both as a theory of the ordinary conception and as a replacement of the ordinary notion, assuming the latter is defective. (shrink)

I here respond to Pietro Salis’s objections against my original critique of the Prosentential Theory of Truth. In addition, I clarify some points regarding the relationship between anaphoric relationships and “general semantic notions” like “equivalence”, “consequence”, and “sameness of content”, and make some further points about ’s ability gto explain pragmatic and expressive features of “true”.

Recreational Drugs European Network (ReDNet) project aims to use the Psychonaut Web Mapping Project database (Psychonaut Web Mapping Group, 2009) containing novel psychoactive compounds usually not mentioned in the scientific literature and thus unknown to clinicians as a unique source of information. The database will be used to develop an integrated ICT prevention approach targeted at vulnerable individuals and focused on novel synthetic and herbal compounds and combinations. Particular care will be taken in keeping the health professionals working directly with (...) young people showing problematic behaviors regularly updated in terms of novel compounds and combinations as well. A user-friendly project website will be developed aimed primarily at delivering the information/prevention approaches, but will also be a way of communicating with project partners and relevant stakeholders (e.g. thematic forum facilities, instant messages, blogs, video chat, wikiblog, newsletters distributed via mailing list). The website will support various ICT prevention tools, including an SMS alert service. Different areas and sections will be aimed specifically at the different target groups. -/- . (shrink)

The gene's-eye view of evolution is an influential but contentious perspective on biology. It emerged in the aftermath of the Modern Synthesis and both proponents and detractors have stressed the link between the two. In particular, both the Modern Synthesis and the gene's-eye view have been criticized for overemphasizing the role genes at the expense of organisms in evolutionary explanations. In this chapter, I discuss the connection between the Modern Synthesis and the gene’s-eye view and evaluate the status of genes (...) and organisms in contemporary biology. I show that while the gene’s-eye view traces its origin back to the Modern Synthesis, it can most accurately be said to represent a specific – adaptationist and gene-centric – version of it. To assess the role of genes and organisms, I examine the intimate relationship between the gene’s-eye view and another post-Synthesis development, the concept of inclusive fitness. I argue that the popularity and influence of inclusive fitness theory demonstrate that the individual organism remains safe at the heart of modern evolutionary biology. (shrink)

The thesis of Weak Unrestricted Composition says that every pair of objects has a fusion. This thesis has been argued by Contessa and Smith to be compatible with the world being junky and hence to evade an argument against the necessity of Strong Unrestricted Composition proposed by Bohn. However, neither Weak Unrestricted Composition alone nor the different variants of it that have been proposed in the literature can provide us with a satisfying answer to the special composition question, or so (...) we will argue. We will then go on to explore an alternative family of purely mereological rules in the vicinity of Weak Unrestricted Composition, Cardinal Composition: A plurality of pairwise non-overlapping objects composes an object iff the objects in the plurality are of cardinality smaller than $$\kappa $$ κ. As we will show, all the instances for infinite $$\kappa $$ κ s determine fusion and are compatible with junk, and every instance for a $$\kappa > \aleph _0$$ κ > ℵ 0 is furthermore compatible with gunk and dense chains of parthood. (shrink)

There is converging evidence that high doses of hallucinogenic drugs can produce significant alterations of self-experience, described as the dissolution of the sense of self and the loss of boundaries between self and world. This article discusses the relevance of this phenomenon, known as “drug-induced ego dissolution (DIED)”, for cognitive neuroscience, psychology and philosophy of mind. Data from self-report questionnaires suggest that three neuropharmacological classes of drugs can induce ego dissolution: classical psychedelics, dissociative anesthetics and agonists of the kappa opioid (...) receptor (KOR). While these substances act on different neurotransmitter receptors, they all produce strong subjective effects that can be compared to the symptoms of acute psychosis, including ego dissolution. It has been suggested that neuroimaging of DIED can indirectly shed light on the neural correlates of the self. While this line of inquiry is promising, its results must be interpreted with caution. First, neural correlates of ego dissolution might reveal the necessary neurophysiological conditions for the maintenance of the sense of self, but it is more doubtful that this method can reveal its minimally sufficient conditions. Second, it is necessary to define the relevant notion of self at play in the phenomenon of DIED. This article suggests that DIED consists in the disruption of subpersonal processes underlying the “minimal” or “embodied” self, i.e., the basic experience of being a self rooted in multimodal integration of self-related stimuli. This hypothesis is consistent with Bayesian models of phenomenal selfhood, according to which the subjective structure of conscious experience ultimately results from the optimization of predictions in perception and action. Finally, it is argued that DIED is also of particular interest for philosophy of mind. On the one hand, it challenges theories according to which consciousness always involves self-awareness. On the other hand, it suggests that ordinary conscious experience might involve a minimal kind of self-awareness rooted in multisensory processing, which is what appears to fade away during DIED. (shrink)

If $U$ is a normal ultrafilter on a measurable cardinal $\kappa$, then the intersection of the $\omega$ first iterated ultrapowers of the universe by $U$ is a Prikry generic extension of the $\omega$th iterated ultrapower.

I. Introduzione. I.1. Un’editio minor come sfida aperta. I.2 Per una più selettiva eliminatio. II.1 Sulla storia del problema : l’eredità del XIX secolo (Brandis 1823, Christ 1885, Gercke 1892) nelle edizioni del XX (Ross 1924, Jaeger 1957). II.2. Studi recenti : la necessità di un superamento. II.3. Lo stemma di riferimento : Harlfinger (1979). II.4. L’applicazione dello stemma nel libro Alpha edito da Primavesi. II.5. La revisione dello stemma, proposta per Kappa e Lambda (2009, 2010). II.6. La reazione : (...) discussioni sul ruolo della tradizione β in Kappa e Lambda (2015). III. Una verifica dello stemma in agenda : la divisione delle due famiglie. III.1 Fra i codici β : L’Ambrosianus F 113 Sup. come codex descriptus ? (libri I-IX inc.). III.2. L’ipotesi dell’ interpositus ε e le sue implicazioni sistematiche. III.3 Allievo e maestro nel XV secolo : Matthaios Chamariotes (C) e Giorgio Scholarios, Gennadeios II (Vk). III.4. Il non liquet sulle parti inferiori dello stemma e il concetto di contaminazione. IV.1. Rivedendo lo stemma dall’interno : il problema critico degli errori-guida (Leitfehler). IV.2. Iudicium e valutazione degli errori. IV.3. Errori separativi ed errori congiuntivi secondo la Textkritik di Paul Maas. IV.4. Una verifica importante : il ruolo di γ. V. Un’ipotesi alternativa . V.1. Il testo della Metafisica nei codici poziori. V.2. Un ritorno alla sigla ". V.3. Un nuovo stemma dei codici principali della Metafisica. Appendice : una verifica sull’ipotesi γ. (shrink)

The Meaning of Things explores the meanings of household possessions for three generation families in the Chicago area, and the place of materialism in American culture. Now regarded as a keystone in material culture studies, Halton's first book is based on his dissertation and coauthored with Mihaly Csikszentmihalyi. First published by Cambridge University Press in 1981, it has been translated into German, Italian, Japanese, and Hungarian. The Meaning of Things is a study of the significance of material possessions in contemporary (...) urban life, and of the ways people carve meaning out of their domestic environment. Drawing on a survey of eighty families in Chicago who were interviewed on the subject of their feelings about common household objects, Mihaly Csikszentmihalyi and Eugene Rochberg-Halton provide a unique perspective on materialism, American culture, and the self. They begin by reviewing what social scientists and philosophers have said about the transactions between people and things. In the model of 'personhood' that the authors develop, goal-directed action and the cultivation of meaning through signs assume central importance. They then relate theoretical issues to the results of their survey. An important finding is the distinction between objects valued for action and those valued for contemplation. The authors compare families who have warm emotional attachments to their homes with those in which a common set of positive meanings is lacking, and interpret the different patterns of involvement. They then trace the cultivation of meaning in case studies of four families. Finally, the authors address what they describe as the current crisis of environmental and material exploitation, and suggest that human capacities for the creation and redirection of meaning offer the only hope for survival. A wide range of scholars - urban and family sociologists, clinical, developmental and environmental psychologists, cultural anthropologists and philosophers, and many general readers - will find this book stimulating and compelling. Translations: Il significato degli oggetti. Italian translation. Rome: Edizione Kappa, 1986. Der Sinn der Dinge. German translation. Munich: Psychologie Verlags Union, 1989. Japanese translation 2007. Targyaink tukreben. Hungarian translation, 2011. (shrink)

Objective: We aimed to investigate the image quality of paranasal sinus computed tomography (CT) scans obtained with the “Advanced intelligent Clear-IQ Engine” (AICE) software and ultra-low dose parameters in patients with prediagnosed rhinitis, sinusitis or nasal septum deviation. -/- Methods: The first 50 patients (31 men and 19 women, aged 18-70 years) who agreed to participate in our prospectively planned study were included in the study. Imaging of the patients was performed with a 160-slice multidetector CT device Canon Aquilion Prime (...) SP (Canon Medical Systems, Otawara, Japan). Tube voltage of 80 kV and tube current of 40 mA were chosen. The effective radiation dose (ED) was calculated based on the “dose-length product” (DLP) information of each patient. Evaluation of images was made on reformat images made with “AiCE Bone” filter in the axial and coronal planes. All images were double-blindly evaluated by 2 radiologists out of 5 points (5 = very good; 1 = not diagnostic). The visibility of 17 bilateral important anatomical landmarks examined on paranasal sinus CT was scored (0 = not visible; 2 = completely visible). In the evaluation of images, the agreement between radiologists was evaluated with Kappa statistics. -/- Results: The median ED value of the CT protocol was 0.015±0.001 mSv [range 0.012-0.017 mSv]. The overall image quality of the images in our study was interpreted as 4 (good) or 3 (moderate) for all patients. Inter-research agreement was 92%. Most of the anatomical landmarks evaluated were completely visible. Six (bilateral of three) anatomical landmarks could be partially visible in some patients. -/- Conclusion: Combining the ultra-low dose CT protocol and the AiCE reconstruction algorithm makes it possible to achieve very low ED values ​​in paranasal sinus CT scans and still obtain sufficient image quality in indications such as septum deviation and sinusitis. (shrink)

Teachers are the frontline workers in sustaining quality education; hence, assessing their knowledge, attitudes, and behaviors (KAB) allows them and the administrators to create better training, programs, and instructional materials. The objective is to develop and validate a quick and accessible online instrument to assess the teachers’ KAB towards sustainable development in the Philippine context, as part of a bigger project to integrate Pili (Canarium ovatum) into education. The researchers administered the instrument using a cross-sectional survey method through Google Forms (...) in which respondents (n = 206) had voluntarily answered. The 24-item tool, anchored on the 2030 sustainable development goals and their complex systems, is reliable and valid based on the confirmatory factor analysis, and Cronbach’s alpha and Fleiss’s kappa estimates. The results showed that having favorable knowledge and attitudes toward sustainable development is inadequate to create positive behaviors. The adaptation of the developed instrument, the use of findings for intercultural and cross-cultural studies, and further investigations are recommended. (shrink)

Inflammation is activated by diverse triggers that induce the expression of cytokines and adhesion molecules, which permit a succession of molecules and cells to deliver stimuli and functions that help the immune system clear the primary cause of tissue damage, whether this is an infection, a tumor, or a trauma. During inflammation, short-term changes in the expression and secretion of strong mediators of inflammation occur, while long-term changes occur to specific groups of cells. Long-term changes include cellular transdifferentiation for some (...) types of cells that need to regenerate damaged tissue, as well as death for specific immune cells that can be detrimental to tissue integrity if they remain active beyond the boundaries of essential function. The transcriptional regulator NFκB enables some of the fundamental gene expression changes during inflammation, as well as during tissue development. During recurrence of malignant disease, cell stress-induced alterations enable the growth of cancer cell clones that are substantially resistant to therapeutic intervention and to the immune system. A number of those alterations occur due to significant defects in feedback signal cascades that control the activity of NFκB. Specifically, cell stress contributes to feedback defects as it overrides modules that otherwise control inflammation to protect host tissue. NFκB is involved in both the suppression and promotion of cancer, and the key distinctive feature that determines its net effect remains unclear. This paper aims to provide a clear answer to at least one aspect of this question, namely the mechanism that enables a divergent response of cancer cells to critical inflammatory stimuli and to cell stress in general. (shrink)

Originally titled “Is It Murder in Tennessee to Kill a Chimpanzee,” this article argues in some detail that typical legal definitions of “murder” as involving the intentional killing of “a reasonable being” would require classifying the intentional killing of chimpanzees as murder.