This reflection on the Petrine Ministry is being made freely available to students during this ongoing pandemic of COVID 19. This very brief essay seeks to understand the meaning of the title of the eponymous novel by Graham Greene.

Graham Greene's novels are often read with no reference to his Roman Catholic Faith. Particularly, in India there is little knowledge among both students and scholars about the primacy and the nature of the Roman Catholic Faith. They miss the point that the Roman Faith is a deeply Mysterious Faith. The term "Mystery" is used here in the Catholic sense of that Faith's 'Mysteries'. The essay and the long endnotes try to rectify the errors which creep in (...) when Greene is decontextualized from his Faith by logical positivists. In the name of the 'death of the author' religious relativists contaminated with the heresies of modernism misinterpret Greene. 'Heresies of Modernism' will be alien to those whose academic limits do not go beyond staid woke-seminars. -/- The essay is discursive in nature, but on purpose. It sees Greene's works through the lens of the Suffering Servant and Paul's Hymn to Love. It has to be kept in mind that Greene is a Roman Catholic writer who knew his Church's teachings well. Christianity is not a homogenous term. "Religious" in the essay often means those who are lead consecrated lives within the Catholic Church as distinct from diocesan clergy. (shrink)

In 1930, the Spanish philosopher Miguel de Unamuno (1864–1936) wrote one of his most well-known novels, San Manuel Bueno, mártir [Saint Manuel Bueno, Martyr]. The novel is about the fictional character Manuel Bueno, a catholic priest from a small Spanish village who, despite being unable to believe the Christian claim that there is an after earthly death life, devotes himself to the spiritual care of his people, being thereby sanctified after his death. The aim of this paper is (...) to show that the guideline of San Manuel Bueno, mártir is the expression, in fictional, non-philosophical language, of the conception of religious faith Unamuno had already defended in his major philosophical work, Del sentimiento trágico de la vida en los hombres y los pueblos [The Tragic Sense of Life in Men and Nations]. (shrink)

A rapidly growing body of scholarship embraces virtue jurisprudence, a series of (often ad hoc) attempts to incorporate the philosophical tradition of virtue ethics into legal theory. Broadly understood, virtue ethics describes an approach to moral questions that emphasizes the importance of developing and embodying various virtues, often as manifestations of human flourishing. Scholars typically contrast virtue ethics with deontological and consequentialist moral theories, tracing virtue-centered analysis to ancient Greek philosophers, and in particular to Aristotle. Virtue ethics has experienced a (...) revival over the past 65 years; but, long before that, it proved especially influential in Catholic moral thought, particularly through the work of Aquinas. Perhaps relatedly, scholars have seized on virtue jurisprudence to defend a range of politically conservative positions, such as originalist constitutional interpretation and the propriety of utilizing the law to regulate ostensibly “private” immoralities. This Article reveals the radically underappreciated progressive promise of virtue jurisprudence. Virtue jurisprudence requires no religious commitments whatsoever, but a strong version entails acceptance of the moral significance of developing one’s character—both within and without the law. On a compelling understanding of the virtues, rejecting a state of perpetual disadvantage under the law is a meaningful marker of the virtue of self-respect, and a repudiation of the vice of servility that would otherwise be imposed by the legal system itself. Thus, contrary to the predominant tenor of research on the subject, virtue jurisprudence can ground significant resistance to—and even defiance of—the law. In making this argument, the Article also draws novel connections between virtue jurisprudence and literature on (inter alia) race, feminism, and sexual orientation to reveal the unnoticed potential of virtue jurisprudence to push forward work in those and related areas. At a time when massive and widespread protests across the United States reflect a groundswell of support for overturning certain long-standing, legally-ingrained, systemic disadvantages of people of color, many might be surprised to learn that virtue jurisprudence can serve as a potent theoretical ally. (shrink)

A Confederacy of Dunces (Confederacy) by John Kennedy Toole portrays an interplay between competing definitions of humanism. The one school of humanism—called by some the Modernist Paradigm—saw the Italian Renaissance as the origin of nineteenth- and twentieth-century modernist views that celebrated science, technology, and individual human freedom. The other school, led by Paul Oskar Kristeller, sought to historicize humanism by establishing that Renaissance writers and thinkers were generally conservative and preserved the philosophical ideas of the medieval era. Kristeller was the (...) President of the Renaissance Society of America and was at the height of his influence at Columbia University during the late 1950s, when Toole studied for his Master’s degree there. The main character in Confederacy, Ignatius J. Reilly, presents a parody of Kristeller’s position, which he uses to critique modern society. Ignatius also plays the part of a child of the planetary god Saturn, both by acting out the ancient astrological tradition of associating Saturn with misfortune and disorder and by being a parody of the Renaissance concept of the Genius as a Child of Saturn begun by the Renaissance philosopher whom Kristeller studied most, Marsilio Ficino. Ignatius’s worldview is an antithesis of the Modernist Paradigm. Confederacy is critical of both Modernist humanism with its attendant materialism and its antithesis—Ignatius’s dysfunctional version of Kristeller’s Renaissance philosophy. When the community expels Ignatius as a scapegoat, Toole appears to gesture toward a dialectical synthesis of the two concepts of humanism in the novel’s happy ending. (shrink)

In this new post-genomic age of medicine and biomedical technology, there will be novel approaches to understanding disease, and to finding drugs and cures for diseases. Hundreds of new “disease genes” thought to be the causative agents of various genetic maladies will be identified and added to the list of hundreds of such genes already identified. Based on this knowledge, many new genetic tests will be developed and used in genetic screening programs. Genetic screening is the foundation upon which (...) reproductive technologies such as pre-natal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are based. Genetic information arising from the human genome may also be used in attempts to redesign the human genetic inheritance by engineering the human germline (germline engineering). In each of these technologies—PND, PGD, and germline engineering—there are serious ethical and social concerns. Moreover, all three are eugenic in nature because they strive to control which genes are passed down to future generations. The goals of this article are threefold: 1) to introduce the science behind the three technologies; 2) to give a brief overview of eugenics in the past century and show how these genetic technologies are eugenic; and 3) to present a vision of social justice that rejects the genetic determinism upon which eugenics is based and embraces a holistic, ecological view of nature and humanity. (shrink)

Extending Alvin Plantinga’s model of warranted belief to the beliefs of groups as a whole, I argue that if the dogmatic beliefs of the Catholic Church are true, they are also warranted. Catholic dogmas are warranted because they meet the three conditions of my model: they are formed (1) by ministers functioning properly (2) in accordance with a design plan that is oriented towards truth and reliable (3) in a social environment sufficiently similar to that for which they (...) were designed. I show that according to Catholic doctrine the authoritative spokespersons of the Church—ecumenical councils and popes—meet these conditions when defining dogmas. I also respond to the objection that the warrant of Catholic dogmas is defeated by the plurality of non-Catholic Christian sects that deny Catholic dogmas. (shrink)

If novels can be arguments, that fact should shape logic or argumentation studies as well as literary studies. Two senses the term ‘narrative argument’ might have are (a) a story that offers an argument, or (b) a distinctive argument form. I consider whether there is a principled way of extracting a novel’s argument in sense (a). Regarding the possibility of (b), Hunt’s view is evaluated that many fables and much fabulist literature inherently, and as wholes, have an analogical argument (...) structure. I argue that a better account is that some novels inherently exhibit a transcendental argument structure. (shrink)

Meaningful work is both a moral issue and an economic one. Studies show that workers’ experience of meaninglessness in their jobs contributes to job dissatisfaction which has negative effects to business. If having a meaningful work is essential for the well-being of workers, providing them with one is an ethical requirement for business establishments. The essay aims to articulate an account of meaningful work in the Catholic social teachings. CST rejects the subjectivist and relativist notion of work which affirms (...) the absolute freedom of individuals to choose their commitment and goals, even if this includes experiencing satisfaction in dehumanizing work. First, the paper will present a summary account of some of the current views on meaningful work from the objective-normative approach. This will be followed by a systematic treatment of the meaning and value of work in the CST, the similarities and differences it has with alternative views, and its implications for the way we promote meaningful work. The paper will argue that by recognizing the subjective and objective dimensions of work and affirming that although the two are inseparable, the former takes priority over the latter; CST develops a holistic, comprehensive, and coherent account of meaningful work which overcomes some of the difficulties that are usually encountered in dealing with this issue from a purely objective approach. (shrink)

The common view is that no novel IS an argument, though it might be reconstructed as one. This is curious, for we almost always feel the need to reconstruct arguments even when they are uncontroversially given as arguments, as in a philosophical text. We make the points as explicit, orderly, and (often) brief as possible, which is what we do in reconstructing a novel’s argument. The reverse is also true. Given a text that is uncontroversially an explicit, orderly, (...) and brief argument, in order to enhance plausibility, our first instinct is to flesh it out with illustrations and relationships to everyday life. If this process is fictive (e.g., with “thought experiments”) and orderly, it is story-telling. This paper investigates whether there is a principled way of determining a novel’s argument, which should contribute as much to understanding arguments as to understanding novels. (shrink)

The highly contagious 2019 novel coronavirus disease (COVID-19) outbreak has not only impacted health systems, economies, and governments, it has also rapidly grown into a global health crisis, which is now threatening the lives of millions of people globally. While, on one hand, medical institutions are critically attempting to find a cure, on the other hand, governments have introduced striking measures and policies to curtail the rapid spread of the disease. Although COVID-19 has achieved pandemic status and is predominantly (...) viewed as a biomedical issue, it is argued that it should also be treated as a psychological crisis. This paper also reviews the literature to examine and comment on the detrimental effects of isolation, which has been enforced as one of the primary preventative measures to manage the spread of COVID-19. This paper further outlines key recommendations that should be addressed across different levels to buffer against the known adverse effects of isolation, which is especially relevant for the current COVID-19 situation, where a large proportion of the global population is isolated, confined, and/or quarantined. (shrink)

This article presents an ethical analysis and critique of personalized service in the tradition of Catholic social teaching (CST) that is both Catholic and Personalist. It tackles the ethical issues involved when service delivery is personalized, issues that affect both the consumers and the service providers. It focuses on nonprofessional services that are offered by low-skilled blue-collar workers through corporations that are organized to produce efficient service to a high volume of consumers. Customer service involves intersubjectivity, that is, (...) interaction between two persons as subjects. Ethics in the service context is not only about treating consumers in a just manner; the threats to the personhood of the service providers are also significant, for their work cannot be separated from their very being. By focusing on the ethical issues of emotional labor and consumerism of human service, the study will argue that the human interaction in personalized service runs the risk of alienating us from our authentic selves and from each other. If the objective of personalized service is to create authentic human relationship in the service encounter, the latter can arise even in a nonpersonalized service. We do not have to personalize our actions in order to create genuine human interaction. Instead, what we must do is to treat each other as persons. (shrink)

Collection of articles on themes of Australian Catholic philosophy and history. Articles of philosophical interest include 'Catholic thought and Catholic Action: Dr Paddy Ryan MSC' (on the scholastic philosopher and anti-Communist), 'Catholic schooldays with philosophy', 'Traditional Catholic philosophy: baby and bathwater', 'Secular versus Catholic conceptions of values in Australian education', 'Accountancy as computational casuistics', 'The Mabo High Court and natural law values', and 'Stove, Hume and Enlightenment'.

The teaching of the Aquinas Academy in its first thirty years was based on the scholastic philosophy of Thomas Aquinas, then regarded as the official philosophy of the Catholic Church. That philosophy has not been so much heard of in the last thirty years, but it has a strong presence below the surface. Its natural law theory of ethics, especially, still informs Vatican pronouncements on moral topics such as contraception and euthanasia. It has also been important in Australia in (...) the High Court’s deliberations on the Mabo case. It is argued that some officially-sanctioned deductions on particular cases have not been correct, but that any attempt to do without a natural law foundation of ethics would throw out the baby with the bathwater. The sense of the basic objective worth of persons that is the centre of natural law ethics is essential to any ethics better than a simple “might is right” approach. (shrink)

Mainstream teleosemantics is the view that mental representation should be understood in terms of biological functions, which, in turn, should be understood in terms of selection processes. One of the traditional criticisms of teleosemantics is the problem of novel contents: how can teleosemantics explain our ability to represent properties that are evolutionarily novel? In response, some have argued that by generalizing the notion of a selection process to include phenomena such as operant conditioning, and the neural selection that (...) underlies it, we can resolve this problem. Here, we do four things: we develop this suggestion in a rigorous way through a simple example, we draw on recent neurobiological research to support its empirical plausibility, we defend the move from a host of objections in the literature, and we sketch how the picture can be extended to help us think about more complex “conceptual” representations and not just perceptual ones. (shrink)

Much attention has been given to the question of ontic vagueness, and the issues usually center around whether certain paradigmatically concrete entities – cats, clouds, mountains, etc. – are vague in the sense of having indeterminate spatial boundaries. In this paper, however, I wish to focus on a way in which some abstracta seem to be locationally vague. To begin, I will briefly cover some territory already covered regarding certain types of “traditional” abstracta and the ways they are currently alleged (...) to be vague. I then wish to discuss two types of “nontraditional” abstracta and the sense in which I think some of these objects are locationally vague. I will next reexamine some of the traditional abstracta and discuss whether any of these objects are locationally vague in the novel way suggested for the nontraditional sorts. I’ll finish by discussing objections, and conclude with some remarks about characterizing the abstract/concrete distinction. (shrink)

Authors: Joseph M. Eble, John A. Di Camillo, Peter J. Colosi. --- NEWS RELEASE For Immediate Release February 27, 2024 Contact: Joseph M. Eble, MD Corresponding author 919-667-5206 -/- The statement, Catholics United on Brain Death and Organ Donation: A Call to Action (HTML), was published on February 27, 2024. It was prepared by Joseph Eble, a physician and President of the Tulsa Guild of the Catholic Medical Association; John Di Camillo, an ethicist of The National Catholic Bioethics (...) Center; and Peter Colosi, a philosophy professor at Salve Regina University. -/- Catholic United explains that the criteria for brain death establish only partial loss of brain function. This is now abundantly clear based on scientific studies, a recent effort to lower the legal standard for death, and updated brain death guidelines issued in October 2023. -/- Catholics United bridges a divide among faithful Catholics about whether the concept of brain death aligns with Church teaching. Some Catholics hold that brain death represents true death when there is complete and irreversible cessation of all brain activity, often called whole brain death. Others hold that brain death does not represent true death. Since the existing criteria establish only partial loss of brain function, all the endorsers—whether they accept or reject whole brain death as true death—agree that “the current brain death criteria in widespread use do not provide moral (prudential) certainty of death.” -/- Catholics United calls on health care professionals and institutions to cease organ harvesting that relies on the inadequate criteria, noting that 70% of all donors are declared dead using brain death criteria. “Given the lack of moral certainty of death whenever the current brain death criteria are used,” the statement affirms, “a clear majority of vital organ donors can be presumed alive at the time of organ harvesting.” Since the Catholic Church forbids removing vital organs when this would kill the patient, “it is therefore wrong to remove organs from patients declared dead using these inadequate criteria.” . (shrink)

This paper analyzes how Jacques Maritain anticipated much of the questions that can be raised concerning the Church’s active participation today in matters that many have supposed to pertain only to politics: To what extent is the Church’s involvement in political life permissible in light of its perceived duty to translate its apostolic and spiritual values into social actions? What boundaries does the Church recognize regarding a proper delineation between the spiritual and temporal spheres towards the linking of which (...) class='Hi'>Catholic Action is said to be directed? To what limits can the Church exercise its auctoritas within a personalist democracy that emphasizes the common good as its chief aim for the human community? Insights in response to these will show that far from ‘meddling’ with or ‘disrupting’ the political order, the Church’s approaches are sensible and just within a democracy that Philippine politics embraces. (shrink)

In the 1960s, the Catholic Church made changes to its liturgy and ecumenical outlook during the Second Vatican Council. These changes sparked a small counter-revolution called the Traditionalists led by rebel Archbishop Marcel Lefebvre to keep the Latin Mass. My grandparents Derrick and Irene Taylor opened their home to the movement during the 1970s, offering their time, money and land for SSPX masses. They received backlash from modernist Catholics and Church leaders but held to their belief that the Traditionalists (...) were to save the Church. My research has sought to uncover why my grandparents involved themselves in the movement. (shrink)

In this paper I will take it for granted that Zagzebski's position articulates a broadly Catholic perspective, and that Plantinga's position accurately represents a broadly Calvinist one. But I will argue that so construed, the Catholic and the Calvinist are much closer than Zagzebski implies: both views are person-based in an important sense of that term; both are internalist on Zagzebski's usage and externalist on the standard usage; and Plantinga's position is consistent with the social elements that Zagzebski (...) stresses in her view. In the second part of the paper I will identify what I think is the real issue between Zagzebski and Plantinga. Namely, Zagzebski thinks that knowledge requires epistemic responsibility, in the sense that instances of knowledge must be appropriately praiseworthy. Plantinga thinks that no such condition is required for knowledge or warranted belief. I will argue that on this issue Zagzebski is right, and that her virtue approach gives us resources for seeing why. Finally, I will look at the consequences for religious knowledge. Here I will argue that the consequences are minimal. Even if knowledge requires responsibility, Plantinga can still make a good case that religious belief is properly basic. And even if religious belief is properly basic, natural theology can still have an important role in the justification of religious belief. (shrink)

We take up the challenge of developing an international network with capacity to survey the world's scientists on an ongoing basis, providing rich datasets regarding the opinions of scientists and scientific sub-communities, both at a time and also over time. The novel methodology employed sees local coordinators, at each institution in the network, sending survey invitation emails internally to scientists at their home institution. The emails link to a ‘10 second survey’, where the participant is presented with a single (...) statement to consider, and a standard five point Likert scale. In June 2023, a group of 30 philosophers and social scientists invited 20,085 scientists across 30 institutions in 12 countries to participate, gathering 6,807 responses to the statement 'Science has put it beyond reasonable doubt that COVID-19 is caused by a virus'. The study demonstrates that it is possible to establish a global network to quickly ascertain scientific opinion on a large international scale, with high response rate, low opt-out rate, and in a way that allows for significant (perhaps indefinite) repeatability. Measuring scientific opinion in this new way would be a valuable complement to currently available approaches, potentially informing policy decisions and public understanding across diverse fields. (shrink)

The commentary is a detailed analysis of one of the shortest writings (25 verses) and, according to an already classic definition, "The Most Neglected Book in the New Testament” (cf. D. J. Rowston). Thus, it covers an existing gap in the specialized theological literature and is among the newer concerns of biblical scholars, attentive to the enhancement of the corpus of the Catholic Epistles. The interest in such an inspired text lies primarily in the approximately ten new topics it (...) uniquely addresses in the New Testament literature, and also in the issues it exposes, regarding those who have always disturbed the peace of Christian communities: agitators, impostor pseudo-prophets, schismatic heretics, ultimately sectarians. The volume is divided into three essential parts, as announced in the subtitle of the writing: an Isagogical part that reaches the main points related to the authorship, the authority, the structure and the dating of the writing, a more consistent part materialized in a very elaborate Commentary of the text itself. said (verse by verse, we could even say word for word), preceded each time by an adequate Translation of the basic Greek text (also highlighted at the beginning of each section, in bilingual columns) and also a final part which highlights the main Theological Themes of the Letter (Triadology, Eschatology, Angelology, Soteriology, etc.). Through the methods of analysis used, the commentary is a very useful tool for biblical scholars and historians, an informed guide for priests and believers interested in reading and the history of the Holy Scriptures of the New Testament, the reflection on these texts, and their profound theological meaning. (shrink)

Reformed catholicity suffers from a fragility that causes it to easily fragment over comparatively small differences. This study wagers that an important resource that can be useful for addressing this problem is the Chinese philosophy of tianxia. The article introduces the idea of a ‘Reformed catholicity under Heaven’ by placing a more liberal interpretation of tianxia in conversation with the problems in Reformed approaches to the church’s catholicity. In doing so, the article demonstrates tianxia’s ecclesiological usefulness while articulating two dimensions (...) of ‘Reformed catholicity under Heaven’ that can deepen how Reformed churches inhabit catholicity in ways that promote unity. (shrink)

It is unlikely that when my the grandfather of Cometan, Derrick Taylor, sat down to participate in an interview with his good friend Judith Shean now almost thirty years ago that all those years later his grandson would have written a book analysing that very interview. On 22nd February 1995, Derrick Taylor agreed to participate in an interview at his home 222 Longmeanygate to reveal his experience as a Protestant turned Catholic. During the interview, Derrick Taylor provided a realistic (...) view of what his life had been like detailing loss, tragedy and suffering. By contrast, he also detailed his predisposition for experiencing interior locutions – divine communications to the ear – which filled him with great elation in times of spiritual crisis. This interview was titled Light a Candle for Me as based on Derrick Taylor's very first interaction with the Sacred Heart of Jesus when he was just seven years old in which he asked his friend's mother to light a candle for him as a metaphor for his journey to Catholicism. What we ultimately learn of Derrick Taylor's character in this 1995 interview is that he held such a dedication to the Catholic faith that he found it difficult to reconcile the fact that the world and the Church were changing. In this interview, which is now often titled the Sceptre Bulletin Interview, Derrick Taylor tells us in his own words what he thought of the reforms of the Second Vatican Council. This book, the Catholic Conversion, is an exegetical work written by Derrick's grandson Cometan some 27 years later that develops his grandfather's words into a set of theological concepts that come to form Derrick Taylor's definitive approach to Catholicism. (shrink)

ABSTRACT "Why can’t I decide to be happy?" This is the question that encapsulates the meaning behind Gabriele’s story, the main character of the novel Il film delle emozioni (The Movie of Emotions; Calabretta 2007a, in Italian). Gabriele is a victim of his negative emotions, and is completely in the power of his self-blame and self-devaluative thinking, which he learns to change only at the end of the novel, thanks to creativity and to the artistic expression of his (...) own traumatic experiences (see Sparrow and Wegner 2006). The novel tells of Gabriele’s several attempts at writing, first, the script of an autobiographical "educational" movie on emotion regulation; and then at transforming it into a novel. In reality, it reveals itself as a book popularizing the most recent scientific knowledge on psychology of emotions; as a dramatization of a scientist’s life—of his interior, interpersonal, and social conflicts (as well as political ones); and as a dramatization of the creative process of writing. As we will see in this article, The Movie of Emotions is a very particular novel that has much to do with creativity viewed in three different aspects—creativity in the novel’s structure, creativity in the process of the novel’s creation, and proposed techniques to increase creativity. (shrink)

The recent comments by Pope Francis on abortion have caused a bit of a stir in the media. His nuanced responses are often lost in the media, and also by advocates on both sides of the abortion debate. While the Catholic position against abortion is common knowledge, this does not preclude an openness to dialogue. This article looks at some recent attempts at dialogue on the controversial topic of abortion. The first example comes from a book that surveys the (...) public view on abortion that surprisingly finds many areas of common ground. Followed by this is a theological reading of Pope Benedict’s encyclical ‘Charity in truth’ that can be the basis of dialogue between parties with divergent views. A third example refers to a conference in Princeton University three years ago, where I mentioned several points where dialogue could be built. (shrink)

We describe a simple, flexible exercise that can be implemented in the philosophy of science classroom: students are asked to determine the contents of a closed container without opening it. This exercise has revealed itself as a useful platform from which to examine a wide range of issues in the philosophy of science and may, we suggest, even help us think about improving the public understanding of science.

This study examines from an ethical framework the circumstances of workers who are engaged in non-professional services that are offered through corporations that are organized to serve high volume of costumers. Drawing on the relevant ethical teachings of the Catholic social tradition (CST), it explores some practices, strategies, and policies that could address the problems experienced by many service providers in the United States today. CST refers to a wide variety of documents of the magisterium of the Catholic (...) Church which respond to the changing social and economic challenges of the modern world. The study argues that the primacy of the person, love and subsidiarity, sense of community, and respect for worker’s rights and unionism in CST are not only moral principles that uphold intrinsic human goods, they are likewise instrumental to operational effectivity because they promote job satisfaction, smooth interpersonal relationship, and long-term commitment with the company. They enable service providers to work efficiently, deliver exceptional service, and act as conduit between the customers and the business establishment, rather than simply being caught between their conflicting demands. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

This research examines the most important historical, political, economic, social, cultural, and religious factors before, during, and after the reign of Communism in Czechoslovakia from 1918 to 2021 and their effect on the extreme increase in atheism and decrease in Christianity, particularly Roman Catholicism, in the present-day Czech Republic. It devotes special attention to the role of the Clandestine Catholic Church (Ecclesia Silentii) and the changing policies of the Holy See vis-à-vis this Church, examining these policies' impact on the (...) continuing decline of Roman Catholicism in the Czech Republic after the collapse of Communism. The article also deals with Pope Pius XII's Secret Mandates of 1948-1950, the Second Vatican Council, and the Holy See's Ostpolitik. Scholars, who previously relied only on the views of the Czechs, blame the unprecedented drop in Christianity, the near-total destruction of the Catholic Church, and the rise in atheism on the Czechoslovak communist government's four decades of totalitarianism. Although the increase in atheism and decrease in Christianity were substantial during the era of Communism from 1948 to 1989, our data indicate that the decline in Christianity, particularly the historically predominating Roman Catholicism, did not commence with the 1948 communist coup d’état but traces its origins to the breakdown of the Austro-Hungarian Empire after the conclusion of WWI and the establishment of Czechoslovakia on October 28, 1918. What's more, this research shows that the most significant and unprecedented steep deterioration of the Christian Faith, namely Roman Catholicism, did not occur during the era of Communism but only after the Czechoslovak communist government collapsed in 1989. This massive decay did not happen even during the most extraordinary communist persecution of the Catholic Church during the era of Stalinism in Czechoslovakia. This research further finds that the Holy See's ill-advised policies and systematic, sustained, and prevalent failures in leadership, guidance, and teachings are responsible for the near destruction of the Roman Catholic Church and especially the end destruction of the Clandestine Catholic Church (Ecclesia Silentii), in the Czech and Slovak Republics after the fall of Communism. These failures furthermore contributed to the Czech Republic, the historical lands of Bohemia and Moravia that once were in the center of Christendom, degenerating into the most atheist country in Europe and the world today. (shrink)

In the quest to discover the neural bases of cognition, rigorous behavioral tools are equally as important as sophisticated tools for neural intervention. This paper evaluates several episodes in the development of a novel behavioral tool for rodent cognitive testing, the rodent touchscreen operant chamber. Using conceptual tools on offer in the philosophical literature on exploratory experimentation and control, I illuminate how optimization of this behavioral tool and an understanding of the causal knowledge it may be used to generate (...) historically has involved dynamic interplay between community-driven exploratory practices operating in parallel with causal hypothesis-driven research. (shrink)

According to the decomposition thesis, perceptual experiences resolve without remainder into their different modality-specific components. Contrary to this view, I argue that certain cases of multisensory integration give rise to experiences representing features of a novel type. Through the coordinated use of bodily awareness—understood here as encompassing both proprioception and kinaesthesis—and the exteroceptive sensory modalities, one becomes perceptually responsive to spatial features whose instances couldn’t be represented by any of the contributing modalities functioning in isolation. I develop an argument (...) for this conclusion focusing on two cases: 3D shape perception in haptic touch and experiencing an object’s egocentric location in crossmodally accessible, environmental space. (shrink)

Is Nature teaching us about meditation? The lockdown of people inside their homes forced by the novel Coronavirus gave us a glimpse of what is possible for the restoration of the purity of Nature if humanity stops their ceaseless activity for a length of time. At the level of the individual, one can get a glimpse of what is possible for the restoration of the purity of one’s own inner nature, if one stops all the activities of the mind, (...) speech, and body, which is called meditation. There are instances in our life when we momentarily experience this involuntarily. (shrink)

Sexual abuse of minors by Catholic priests has been a persistent and widespread problem in the Church. Although more than 80 percent of victims have been boys, prior studies have rejected the idea that the abuse is related to homosexuality among priests. Available data show, however, that the proportion of homosexual men in the priesthood is correlated almost perfectly with the percentage of male victims and with the overall incidence of abuse. Data also show that while the incidence of (...) abuse is lower today than it was three decades ago, it has not declined as much as is commonly believed, and has recently begun to rise amid signs of episcopal complacency about procedures for the protection of children. (shrink)

The existence of a Catholic Intellectual Tradition (CIT) is not a given, as arguments contra are in balance with arguments pro. An intellectual tradition consists of a style of thought and of a worldview, as its formal and material modes. The former defines the way knowledge is appropriated, processed, and passed on whereas the latter amounts to its applications to various regions of reality – God, man, morality, society, the Church, etc. A model of the CIT is proposed that (...) consists of principles differentiated by the degree of centrality they have in a topological structure. The paper asserts the existence of a CIT because a non-stipulative, non-trivial, and non-circular case can be made for it. (shrink)

One of the main features that distinguish modern novel from traditional one is the use of new narrative techniques such as monologue, flow of consciousness, leitmotiv and intertextuality. These techniques relate to new approaches that take shape in formal elements such as time, characters and event patterns that make up the modern novel. Which expression technique is used in the work is often related to the form and content of the novel. This research examines the Kevâbîsu Beyrût, (...) which uses modern and post modern expression techniques in the Arab novels of the last century, in the context of the content of the work and reveals the appropriateness of the techniques used for the purpose of the work. The authors of the novel, autobiographical, tried to convey the feelings of a civil war in many ways, and remained in the midst of conflicts. The techniques that came to the forefront in his narration have added aesthetic value to the composition of the narration and it has become one of the famous Arab novels. The introduction part of the work consists of the factors that prepared the ground for the civil war that took place in Lebanon between 1975 and 1990, the first chapter, the work of writer Gâde es-Semman, the third chapter; Kevâbîsu will investigate the relation between the narrative techniques of the novel Beirut and the factors leading to the writing of the work. (shrink)

In recent years official Roman Catholic documents have addressed the ecological crisis from the perspective of Catholic social teaching. This expansion of Catholic social thought addresses the social and ecological question. This paper links environmental and human ecology with the concept of sustainability and proposes an interpretation of the common good and a definition of sustainability within Catholic social teaching. Our treatment of sustainability and Catholic social teaching includes: an analysis of the ecological processes that (...) sustain nature; insights from human ecology, and an examination of models of sustainability as a foundation for re-structuring society to promote the common good. The paper provides a summary of the historical expansion of the common good within modern Catholic social thought, and concludes with an ecological interpretation of the common good and a definition of sustainability within the Catholic understanding of justice. (shrink)

This article offers a novel, conservative account of material constitution, one that incorporates sortal essentialism and features a theory of dominant sortals. It avoids coinciding objects, temporal parts, relativizations of identity, mereological essentialism, anti-essentialism, denials of the reality of the objects of our ordinary ontology, and other departures from the metaphysic implicit in ordinary ways of thinking. Defenses of the account against important objections are found in Burke 1997, 2003, and 2004, as well as in the often neglected six (...) paragraphs that conclude section V of this article. (shrink)

religion, between self realization and desire.

Is the flavor of mint reducible to the minty smell, the taste, and the menthol-like coolness on the roof of one’s mouth, or does it include something over and above these—something not properly associated with any one of the contributing senses? More generally, are there features of perceptual experiences—so-called novel features—that are not associated with any of our senses taken singly? This question has received a lot of attention of late. Yet surprisingly little attention has been paid to the (...) question of what it means to say that a feature is associated with a sensory modality in the first place. Indeed, there is only one fully developed proposal in the literature, due to Casey O’Callaghan. I argue that this proposal is too permissive to inform the debate over novel features. I go on to argue that all attempts to formulate a better proposal along these lines fail. The corollary of my arguments is that the question of the existence of novel features is poorly formed. Furthermore, the problem generalizes, with the result that we should not rely on our pre-theoretical notions of the senses as the basis of theorizing about the features of perceptual experiences. (shrink)

In graph theory, the concept of domination is essential in a variety of domains. It has broad applications in diverse fields such as coding theory, computer net work models, and school bus routing and facility lo cation problems. If a fuzzy graph fails to obtain acceptable results, neutrosophic sets and neutrosophic graphs can be used to model uncertainty correlated with indeterminate and inconsistent information in arbitrary real-world scenario. In this study, we consider the concept of domination as it relates to (...) single-valued neutrosophic incidence graphs (SVNIGs). Given the importance of domination and its utilization in numerous fields, we propose the application of dominating sets in SVNIG with valid edges. We present some relevant definitions such as those of valid edges, cardinality, and isolated vertices in SVNIG along with some examples. Furthermore, we also show a few significant sets connected to the dominating set in an SVNIG such as independent and irredundant sets. We also investigate a relationship between the concepts of dominating sets and domination numbers as well as irredundant and independence sets in SVNIGs. Finally, a real-life deployment of domination in SVNIGsis investigated in relation to COVID-19 vaccination locations as a practical application. (shrink)

Risk is an intrinsic part of our lives. In the future, the development and growth of the Internet of things allows getting a huge amount of data. Considering this evolution, our research focuses on developing a novel concept, namely Holistic Risk Assessment (HRA), that takes into consideration elements outside the direct influence of the individual to provide a highly personalized risk assessment. The HRA implies developing a methodology and a model. This paper is related to the epistemological positioning of (...) this research. We consider this research as an artificial science under the constructivism paradigm. We also introduce the positioning of this research in the complexity science paradigm. We end this paper by presenting a methodology based on an adapted Design Thinking Model. (shrink)

An account of the life of Dr P.J. Ryan, Australian Catholic scholastic philosopher and anti-Communist organiser.

Somewhat traumatized by the Galileo Affair the Church until recently showed low profile in the conflicts with science, evolutionary theory included. The talk presents a categorization of possible relationships between science and religion by distinguishing between "Galilean conflicts", which are about mutually exclusive statements about matters of fact, and Freudian conflicts where an empirical science tries to explain away religion as a phenomenon in its own right. In the light of this distinction I deal with the reactions of the Church (...) since 1859, particularly with the ambiguous position of the present Pope. (shrink)

In this paper a possible extension of Turing test [1] will be presented, which is intended to overcome the limits highlighted by several researchers and scientists in the last seventy years. The main problem related to the execution in Turing test is substantially dealing with the trouble in identification of a human-like intelligence based on a pure evaluation of external behavior of a machine. In this work first of all a description of classical Turing test will be done. After that, (...) some of the main exceptions or oppositions to the Turing test ability to detect “intelligent machines” will be presented. The Lovelace test will be presented as well, as possible alternative to Turing Test, and some considerations on its scope and effectiveness will be made. Furthermore, some references to Penrose and Hofstadter ideas will be recalled, highlighting the strongest troubles in defining and detecting a human-like intelligence, intended as “self-consciousness”. Finally, the new approach will be explained, introducing the new test intended to overcome the troubles highlighted on Turing test execution, based on a model of the self-consciousness obtained by means of the hypersets theory. An example will be presented as well, in order to clarify the proposed approach and its goal. (shrink)

There is considerable disagreement about the epistemic value of novel predictive success, i.e. when a scientist predicts an unexpected phenomenon, experiments are conducted, and the prediction proves to be accurate. We survey the field on this question, noting both fully articulated views such as weak and strong predictivism, and more nascent views, such as pluralist reasons for the instrumental value of prediction. By examining the various reasons offered for the value of prediction across a range of inferential contexts , (...) we can see that neither weak nor strong predictivism captures all of the reasons for valuing prediction available. A third path is presented, Pluralist Instrumental Predictivism; PIP for short. (shrink)

John Patrick Rudisill purports to identify various problems with my argument that the state promotion of autonomy is consistent with anti-perfectionism, viz. that it falsely pretends to be novel, is unacceptably counterintuitive because too restrictive and too permissive, and that it deploys self-defeating formal apparatus. I argue, in reply, that my argument is more novel than Rudisill gives me credit for; that properly understood my anti-perfectionism implies neither the implausible restrictions nor the unpalatable permissions that Rudisill claims; and (...) that my formal apparatus is innocent of the flaws imputed to it. (shrink)

With the proliferation of sophisticated cyber threats, traditional malware detection techniques are becoming inadequate to ensure robust cybersecurity. This study explores the integration of deep learning (DL) techniques into malware detection systems to enhance their accuracy, scalability, and adaptability. By leveraging convolutional neural networks (CNNs), recurrent neural networks (RNNs), and transformers, this research presents an intelligent malware detection framework capable of identifying both known and zero-day threats. The methodology involves feature extraction from static, dynamic, and hybrid malware datasets, followed by (...) training DL models to classify malicious and benign software with high precision. A robust experimental setup evaluates the framework using benchmark malware datasets, yielding a 96% detection accuracy and demonstrating resilience against adversarial attacks. Real-time analysis capabilities further improve response times, reducing the risk of potential damage. The study also incorporates visualization tools to provide interpretable insights into model decisions, enhancing transparency for cybersecurity practitioners. Concluding with a discussion on the challenges and future prospects, this research paves the way for scalable, AI-driven solutions to combat evolving cyber threats. (shrink)

This paper is about the modern-day problem of human alienation and fulfillment in work from the perspective of the Catholic social thought. It analyses the symptoms and causes of work alienation, the meaning of work and its significance in the individual’s quest for fulfillment, and how the Catholic social teachings can shed light on the problems involved in transforming the world of work. Alienation in work affects one’s subjective and psychological fulfillment, but it is not ultimately dependent on (...) material culture or economic models. The problem of alienation in work cannot be dealt with by simply modifying the production process or the wage system, although these are factors that alienate people even more. Social problems cannot be solved without light of faith and the recognition of the moral order that is rooted in God. In the final analysis, alienation is not simply the loss of meaning in human activities. It is the loss of life’s meaning and man’s estrangement from his own authentic nature, including his reason for being and final end, that results from the rejection of God and His teachings. What Catholicism provides is a combination of economic, psychological, moral, social, and spiritual motives for work that will make it personally fulfilling. (shrink)