Despite the importance of human blood to clinical practice and research, hematology and blood transfusion data remain scattered throughout a range of disparate sources. This lack of systematization concerning the use and definition of terms poses problems for physicians and biomedical professionals. We are introducing here the Blood Ontology, an ongoing initiative designed to serve as a controlled vocabulary for use in organizing information about blood. The paper describes the scope of the Blood Ontology, its stage of development and some (...) of its anticipated uses. (shrink)

We describe the rationale for an application ontology covering the domain of human body fluids that is designed to facilitate representation, reuse, sharing and integration of diagnostic, physiological, and biochemical data, We briefly review the Blood Ontology (BLO), Saliva Ontology (SALO) and Kidney and Urinary Pathway Ontology (KUPO) initiatives. We discuss the methods employed in each, and address the project of using them as starting point for a unified body fluids ontology resource. We conclude with a description of how the (...) body fluids ontology initiative may provide support to basic and translational science. (shrink)

Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens. We also observe additional elements relating to social relations in which the healthcare consumer is involved. To provide a consensus representation of common data and to enhance interoperability between different EHR repositories we have created a solution grounded in formal ontology. Here, we present how (...) an ontology for the obstetric and neonatal domain deals with these general elements documented in health care encounters. Our goal is to promote the interoperability of information among EHRs created in different specialties. To develop our ontology, we used two main approaches: one based on ontological realism, the other based on the principles of the OBO Foundry, including reuse of reference ontologies. (shrink)

This paper presents the Obstetric and Neonatal Ontology (OntONeo). This ontology has been created to provide a consensus representation of salient electronic health record (EHR) data and to serve interoperability of the associated data and information systems. More generally, it will serve interoperability of clinical and translational data, for example deriving from genomics disciplines and from clinical trials. Interoperability of EHR data is important to ensuring continuity of care during the prenatal and postnatal periods for both mother and child. As (...) a strategy to advance such interoperability we use an approach based on ontological realism and on the ontology development principles of the Open Biomedical Ontologies Foundry, including reuse of reference ontologies wherever possible. We describe the structure and coverage domain of OntONeo and the process of creating and maintaining the ontology. (shrink)

The main aim in the forthcoming discussion is to contrast theistic modal realism and theistic actualist realism. Actualist realism is the dominant view among theists and presents the most serious challenge to theistic modal realism. I discuss various prominent forms of theistic actualist realism. I offer reasons for rejecting the view of metaphysical reality that actualist realism affords. I discuss theistic modal realism and show that the traditional conception of God is perfectly consistent with the metaphysics of genuine modal realism. (...) Indeed theistic modal realism is more suited to traditional theism than is any version of actualist realism. (shrink)

In Sections 1–7, I provide a detailed description of some of the advantages of theistic modal realism. The aim is to show specifically how theistic modal realism solves many of the intractable problems of philosophical theology. A detailed description of all of the advantages would require a much longer treatment. The aim is to give a good sense of the theoretical benefits that theistic modal realism affords traditional theists. I offer some concluding remarks in Section 8.

Perhaps the greatest impediment to a viable libertarianism is the provision of a satisfactory explanation of how actions that are undetermined by an agent's character can still be under the control of, or 'up to', the agent. The 'luck problem' has been most assiduously examined by Robert Kane who supplies a detailed account of how this problem can be resolved. Although Kane's theory is innovative, insightful, and more resourceful than most of his critics believe, it ultimately cannot account for the (...) type of control that moral responsibility and agency legitimately require. (shrink)

The book discusses the structure, content, and evaluation of cosmological arguments. The introductory chapter investigates features essential to cosmological arguments. Traditionally, cosmological arguments are distinguished by their appeal to change, causation, contingency or objective becoming in the world. But none of these is in fact essential to the formulation of cosmological arguments. Chapters 1-3 present a critical discussion of traditional Thomistic, Kalam, and Leibnizian cosmological arguments, noting various advantages and disadvantages of these approaches. Chapter 4 offers an entirely new approach (...) to the cosmological argument - the approach of theistic modal realism. The proper explananda of cosmological arguments on this approach is not change, causation, contingency or objective becoming in the world. The proper explananda is the totality of metaphysical reality - all actualia and all possibilia. The result is the most compelling and least objectionable version of the cosmological argument. (shrink)

The goal of this paper is to assess biological naturalism in light of the adaptationist debate. Searle is famous for explicity pursuing a biological foundation for his theory of consciousness. However, evolutionary biology receives little attention in his work, which results in crucial theoretical confusions over adaptationism. In this paper, we will propose two theses concerning Searle's approach to consciousness in the context of the adaptationist debate. First, Searle's attack on adaptationism only applies to its naive version, failing to touch (...) any of the more sophisticated versions of adaptationism, especially the empirical one. Second, despite his attack, in the end Searle embraces empirical adaptationism about consciousness. Howsoever, Searle's empirical foundation for his thesis that the evolutionary advantage of consciousness lies in a greater power of discrimination faces a serious problem of generalization regarding non-human animals. (shrink)

This paper will show how Capitalism can prosper up to determined limit and its reasons for crises. We also show a mathematical proof of why capitalism system isn't stable, and for survival, it's either necessary to achieve new markets or keep a more indebted society. For both cases the system won't be stable and this consequently involves to its end.

Sceptical theists--e.g., William Alston and Michael Bergmann--have claimed that considerations concerning human cognitive limitations are alone sufficient to undermine evidential arguments from evil. We argue that, if the considerations deployed by sceptical theists are sufficient to undermine evidential arguments from evil, then those considerations are also sufficient to undermine inferences that play a crucial role in ordinary moral reasoning. If cogent, our argument suffices to discredit sceptical theist responses to evidential arguments from evil.

Nick Trakakis and Yujin Nagasawa criticise the argument in Almeida and Oppy . According to Trakakis and Nagasawa, we are mistaken in our claim that the sceptical theist response to evidential arguments from evil is unacceptable because it would undermine ordinary moral reasoning. In their view, there is no good reason to think that sceptical theism leads to an objectionable form of moral scepticism. We disagree. In this paper, we explain why we think that the argument of Nagasawa and (...) Trakakis fails to overthrow our objection to sceptical theism. (shrink)

Initially, in this article, we present the foundation on which current science stands. Next, we explain the main stream of modern science, the “Popperian Falsificationism”, and show why the current criticism to the system is flawed. Later, we will prove that the “falsificationism” is logically inconsistent and we will propose a new concept of science, unifying it with philosophy.

In this paper we respond to criticisms by Michael Bergmann and Michael Rea in their “In Defense of Sceptical Theism : A Reply to Almeida and Oppy,” Australasian Journal of Philosophy 83.

Resenha crítica do livro Consciousness Desmystified (Cambridge, MA: MIT Press, 2018) de Todd. E. Feinberg e Jon M. Mallatt.

Property-identical divine-command theory (PDCT) is the view that being obligatory is identical to being commanded by God in just the way that being water is identical to being H2O. If these identity statements are true, then they express necessary a posteriori truths. PDCT has been defended in Robert M. Adams (1987) and William Alston (1990). More recently Mark C. Murphy (2002) has argued that property-identical divine-command theory is inconsistent with two well-known and well-received theses: the free-command thesis and the supervenience (...) thesis. I show that Murphy's argument is vitiated by mistaken assumptions about the substitutivity of metaphysical identicals in contexts of supervenience. The free-command thesis and the supervenience thesis therefore pose no serious threat to PDCT. (Published Online August 11 2004). (shrink)

Mauricio Beuchot proposed in his work Treatise of Analogical hermeneutics (1997) a new interpretative model based in the ancient concept of "analogy". As his proposal is a new hermeneutical model, I describe here some of its main arguments with the aim of analyzing and discussing his analogical method of interpretation. / Mauricio Beuchot propuso en su obra Tratado de hermenéutica analógica (1997) una nueva herramienta interpretativa basada en el antiguo concepto de 'analogía'. Su propuesta refresca los debates en (...) torno a la hermenéutica y ofrece un modelo nuevo para la interpretación, mismo que ha generado interés internacional. Aquí presento dicha propuesta, sobre todo porque la considero lo suficientemente interesante como para estudiarla y debatirla. (shrink)

We call for a new philosophical conception of models in physics. Some standard conceptions take models to be useful approximations to theorems, that are the chief means to test theories. Hence the heuristics of model building is dictated by the requirements and practice of theory-testing. In this paper we argue that a theory-driven view of models can not account for common procedures used by scientists to model phenomena. We illustrate this thesis with a case study: the construction of one of (...) the first comprehensive model of superconductivity by London brothers in 1934. Instead of theory-driven view of models, we suggest a phenomenologically-driven one. (shrink)

El presente texto presenta los resultados de un estudio exploratorio de las interacciones entre el sistema de gobernanza y de los actores como causa de la contaminación del arroyo de San Basilio de Palenque en Colombia. Lo anterior, a partir de la validación de la metodología de enfoque de sistemas socio-ecológicos como método de caracterización de conflictos ambientales con impactos culturales.

William Rowe has argued that if there is an infinite sequence of improving worlds then an essentially perfectly good being must actualize some world in the sequence and must not actualize any world in the sequence. Since that is impossible, there exist no perfectly good beings. I show that Rowe's argument assumes that the concept of a maximally great being is incoherent. Since we are given no reason to believe that the concept of a maximally great being is incoherent we (...) have no reason to believe Rowe's Argument from Improvability is sound. (shrink)

We separate metaphysical from epistemic questions in the evaluation of models, taking into account the distinctive functions of models as opposed to theories. The examples a\are very varied.

I argue that Anselmians ought to abandon traditional Anselmianism in favor of Moderate Anselmianism. Moderate Anselmianism advances the view that a being x = God iff for every essential property P of x, it is secondarily necessary that x has P, for most essential properties of x, it is not primarily necessary that x has P and the essential properties of x include omnipotence, omniscience, perfect goodness and necessary existence. Traditional Anselmians have no cogent response to most a priori atheological (...) arguments. But a priori atheological arguments present no serious problem for moderate Anselmians. Unlike traditional Anselmianism, Moderate Anselmianism explains why a priori atheological arguments can be convincing and nonetheless illusory. (shrink)

Recent work in moral theory includes an intriguing new argument that the vagueness of moral properties, together with two well-known and well-received metaethical principles, entails the incredible conclusion that it is impossible to be moral. I show that the argument equivocates between “it is true that A and B are morally indistinguishable” and “it is not false that A and B are morally indistinguishable.” As expected the argument is interesting but unsound. It is therefore not impossible to be moral.Les travaux (...) récents en théorie morale comprennent un nouvel argument intrigant voulant que le caractère vague des propriétés morales, joint à deux principes métaéthiques bien connus et généralement admis, entraîne une conclusion incroyable, soit qu’il est impossible d’être moral. Je montre que cet argument entretient l’équivoque entre «il est vrai que A et B sont moralement impossibles à distinguer» et «il n’est pas faux que A et B soient moralement impossibles à distinguer». Comme on s’y attendait, l’argument est intéressant mais mal fondé. Il n’est donc pas impossible d’être moral. (shrink)

Michael Martin introduces a non-Humean conception of miracles according to which miracles are events that need not violate a law of nature and are brought about by the exercise of a possibly non-theistic, supernatural power. Call those m-miracles. I consider Martin’s argument that the occurrence of an m-miracle would not confirm the existence of God. Martin presents an interesting argument, but it does not establish that m-miracles would not confirm the existence God. I argue that, on the contrary, it is (...) quite reasonable to conclude that Martin’s m-miracles provide at least some confirmation for the hypothesis that God exists. (shrink)

The standard position on moral perfection and gratuitous evil makes the prevention of gratuitous evil a necessary condition on moral perfection. I argue that, on any analysis of gratuitous evil we choose, the standard position on moral perfection and gratuitous evil is false. It is metaphysically impossible to prevent every gratuitously evil state of affairs in every possible world. No matter what God does—no matter how many gratuitously evil states of affairs God prevents—it is necessarily true that God coexists with (...) gratuitous evil in some world or other. Since gratuitous evil cannot be eliminated from metaphysical space, the existence of gratuitous evil presents no objection to essentially omnipotent, essentially omniscient, essentially morally perfect, and necessarily existing beings. (shrink)

Abstract The distinction between conceptual and nonconceptual contents clearly has consequences for the configuration of the world of humans as well as for the possibility of attributing thought, in the strict sense, to systems and nonhuman organisms. With the aim of clarifying such a distinction, the following paper poses a basic notion of mental state and, especially, a clear definition of concept, along with the fundamental features of the states in which concepts occur. The conclusion of the paper is that (...) we have good and enough reasons to speak of conceptual and nonconceptual contents instead of more-or-less conceptual concepts. It means that there is a distinction of kind, not of degree, between both contents. -/- . (shrink)

A Crítica de Hume ao Argumento do Desígnio José Oscar de Almeida Marques Dep. de Filosofia – UNICAMP -/- RESUMO: É comum considerar que o chamado “argumento do desígnio” (o argumento a posteriori para provar a existência de Deus a partir da ordem e funcionalidade do mundo) teria sido refutado ou seriamente abalado por Hume. Mas a natureza e o alcance dessa alegada refutação são problemáticos, pois Hume muitas vezes expressou suas críticas através de seus personagens e evitou assumi-las (...) diretamente enquanto autor. Em vez de supor que Hume procedeu dessa forma apenas para disfarçar suas verdadeiras convicções e evitar um conflito com as autoridades eclesiásticas, proponho que sua posição nesse assunto não é tão categórica como às vezes se supõe, e que os famosos argumentos de Filo nos Diálogos mostram apenas que é possível que a ordem e funcionalidade do mundo tenham surgido sem a intervenção de um desígnio consciente, mas não podem por si sós dar a essa hipótese o mínimo grau de plausibilidade necessário para torná-la digna de uma séria consideração. De fato, antes da revolução explicativa operada por Darwin um século depois, ninguém estava realmente em condições de vislumbrar uma alternativa plausível à atuação de algum tipo de inteligência na geração da ordem e funcionalidade do mundo. ------------ Some Remarks on Hume’s Critique of the Argument from Design José Oscar of Almeida Marques Dep. of Philosophy - UNICAMP -/- ABSTRACT: The so-called “argument from design” (the a posteriori argument to prove the existence of God from the order and functionality of the world) is commonly considered to have been refuted or seriously impaired by Hume. But the nature and scope of this alleged refutation is problematic because Hume often expressed his critics through other characters’ mouth and avoided to assume them directly as author. Contrarily to the supposition that Hume proceeded in this way only to disguise his true convictions and to avoid a confrontation with the ecclesiastical authorities, I propose that his stance on the matter is not, in fact, as clear-cut as it is sometimes supposed, and that Philo’s famous arguments in the Dialogues show only that it is possible for the order and functionality of the world to have arisen without the intervention of an intelligent design, but cannot by themselves lend to this hypothesis the least degree of plausibility needed to make it worthy of serious consideration. In fact, before the explanatory revolution inaugurated by Darwin a century later, nobody was in position to envisage a plausible alternative to the operation of some sort or other of intelligence in the generation of the order and functionality of the world. (shrink)

[Spanish Abstract] El presente texto presenta los resultados de un estudio exploratorio de las interacciones entre el sistema de gobernanza y de los actores como causa de la contaminación del arroyo de San Basilio de Palenque en Colombia. Lo anterior, a partir de la validación de la metodología de enfoque de sistemas socio-ecológicos como método de caracterización de conflictos ambientales con impactos culturales. [English Abstract] This paper presents the results of an exploratory study of the interactions between the governance system (...) and the actors as a cause of contamination of the San Basilio de Palenque river in Colombia. To do so, the methodology of the socio-ecological systems approach was validated as a method of characterizing environmental conflicts with cultural impacts. (shrink)

The themes addressed by this paper intersect the industrial heritage and its main components, from industrial archeology to the technical landscapes of production. From this point of view, the historic center of São Luís, Brazil as case study has an intrinsic relationship with the Bacanga River. It is the main landscape that is to the surroundings of the historical center tilted by the Unesco. The historic center of São Luís with the sea and the river dialogue between colonial urban occupation (...) and water as a landscape that embraces this urbanization. (shrink)

On assiste, depuis les années 70, à une interminable littérature sur la vie et la pensée de Nietzsche. Ce foisonnement d’études prend des proportions telles, que même des interprétations relativement récentes (Deleuze, Derrida, Klossowski, Sarah Kofman) se voient déjà élevées au rang des classiques. Les thèmes anciens, mêlés à d’autres plus actuels, sont repris, répétés, relus et réécrits dans des perspectives diverses. Ainsi se noue le dialogue d’une philosophie avec de larges pans de culture : Nietzsche et la métaphysique, Nietzsche (...) et la science, Nietzsche et la politique, Nietzsche et la musique, Nietzsche et la religion, Nietzsche et l’antisémitisme, Nietzsche et les Nazis, Nietzsche et le féminin, Nietzsche et la psychanalyse. (shrink)

To try to understand Nietzsche’s conception of Christianity is to try to understand his conception of morality, or to try to analyze, dissect, and diagnose the forces and the relation of forces that underly it, or permeate it. These forces characterize not only the reality as Nietzsche considers it, but also the dynamic of his own writing, thought, and perspective. This is the reason why we can affirm that Nietzsche’s thought and writing are essentially, intrinsically, paradoxical. Indeed, the Nietzschean text (...) unfolds as what constantly resists and escapes the order of discourse as such, which means that it would be a frustrating undertaking to seek a key that discloses and explicates the plurality of meanings that engender and determine the development of his writing. Paradoxically, Nietzschean thought reveals itself only to the extent that it is masked, reread, repeated, rewritten, and stripped of all attempts to master it. In other words, it progresses through a continuous intermingling of forces and, consequently, of values, interpretations, and significations that are unceasingly overcoming and surpassing each other. (shrink)

I examine the difficulties involved in the Aristotelian proposal to identify the knowledge of “what it is” and “why it is”, in order to better understand the outlines that delimit it. I propose that the connections by which Aristotle links definition and explanation, and hence essence and cause, depend on the mutual convertibility between nominal expressions and predicative sentences.