Many philosophers working on virtue theory have resisted the idea that the virtues are practical skills, apparently following Aristotle’s resistance to that idea. Bucking the trend, Matt Stichter defends a strong version of this idea in The Skillfulness of Virtue by marshaling a wide range of conceptual and empirical arguments to argue that the moral virtues are robust skills involving the cognitive-conative unification of Aristotelian phronêsis (‘practical intelligence’). Here I argue that Aristotle overlooks a more delimited kind of practical intelligence, (...) strongly analogous to his own account of phronêsis, that unifies complex forms of expertise such as medicine or even high-level sports. Insofar as the skill model of virtue is compelling, it must draw on a robust conception of practical expertise (technê) like the one developed here rather than the ordinary, anemic conception of practical skills. (shrink)

Over the past thirty years or so, virtues and reasons have emerged as two of the most fruitful and important concepts in contemporary moral philosophy. Virtue theory and moral psychology, for instance, are currently two burgeoning areas of philosophical investigation that involve different, but clearly related, focuses on individual agents’ responsiveness to reasons. The virtues themselves are major components of current ethical theories whose approaches to substantive or normative issues remain remarkably divergent in other respects. The virtues are also increasingly (...) important in a variety of new approaches to epistemology. ... (shrink)

Winner of the American Philosophical Association’s 2019 Essay Prize in Latin American Thought | Western imperialism has received many different types of moral-political justifications, but one of the most historically influential justifications appeals to an allegedly universal form of human nature. In the early modern period this traditional conception of human nature—based on a Western archetype, e.g. Spanish, Dutch, British, French, German—opens up a logical space for considering the inhabitants of previously unknown lands as having a ‘less-than-human’ nature. This appeal (...) to human nature originally found its inspiration in the philosophy of Aristotle, whose ethical thought pervaded the work of European philosophers at the outset of the early modern period and the modern age of empire. Indeed some Spanish writers—most famously, Juan Ginés de Sepúlveda (b. 1494)—explicitly appealed to Aristotle’s moral-political philosophy in order to justify the conquest of the Americas in the early sixteenth century, for instance to justify war against the Aztecs and other indigenous peoples. At the time of European arrival, the Aztec civilization was easily the greatest in Mesoamerica—and yet the Europeans generally considered the Aztec people to be ‘barbaric,’ i.e. less-than-fully-human. (shrink)

This chapter defends an Aristotelian account of patriotism that differs from, and improves upon, the ‘extreme’ account of Aristotelian patriotism defended by Alasdair MacIntyre in a famous lecture. The virtue of patriotism is modeled on Aristotle’s account of the virtue of friendship; and the resulting account of patriotism falls between MacIntyre’s extreme patriotism and Marcia Baron’s moderate patriotism. The chapter illustrates how this plausible Aristotelian account of patriotism can avoid the dilemma that Baron has pressed against MacIntyre’s extreme account. It (...) also illustrates why the virtue of patriotism cannot coexist with willful forms of ignorance. In its discussion of patriotism and ignorance the chapter draws on a recent study (2018) of the especially strong connection in the United States between patriotism and poverty. (shrink)

T. M. Scanlon’s ‘Reasons Fundamentalism’ rejects any naturalistic reduction of normative truths and it also rejects the type of non-naturalism that invokes a ‘special metaphysical reality.’ Here I argue that this still does not commit Scanlon—as some have thought—to an extreme ‘metaethical minimalism’ according to which there are no ‘truth makers’ at all for normative truths. I emphasize that the issue here is not just about understanding Scanlon, since the actual position defended by Scanlon might, more significantly, point the way (...) toward a satisfying non-reductive position in metaethics, one that embodies the ontological modesty that disavows any appeal to a ‘special metaphysical reality’ in Scanlon’s sense. (shrink)

Virtues and reasons are two of the most fruitful and important concepts in contemporary moral philosophy. Many writers have commented upon the close connection between virtues and reasons, but no one has done full justice to the complexity of this connection. It is generally recognized that the virtues not only depend upon reasons, but also sometimes provide them. The essays in this volume shed light on precisely how virtues and reasons are related to each other and what can be learned (...) by exploring this relationship. Virtue’s Reasons is divided into three sections, each of them devoted to a general issue regarding the relationship between virtues and reasons. The first section analyzes how the virtues may be related to, or linked with, normative reasons in ways that improve our understanding of what constitutes virtuous character and ethical agency. The second section explores the reasons moral agents have for cultivating the virtues and how the virtues impact moral responsiveness or development. The final section examines how reasons can be employed in understanding the nature of virtue, and how specific virtues, like modesty and practical wisdom, interact with reasons. This book will be of major interest to scholars working on virtue theory, the nature of moral character, and normative ethics. (shrink)

In De Anima III.3 Aristotle presents his official discussion of phantasia (“imagination” in most translations). At the very outset of the discussion Aristotle offers as an endoxon that “phantasia is that in virtue of which we say that a phantasma occurs to us” (428a1-2). Now a natural reading of this claim, taken up by many commentators, can pose a problem for Aristotle’s overall account of perception. Here I argue that, although it would be silly to deny that Aristotle considers phantasia (...) to be that in virtue of which a phantasma occurs to someone, it is not silly to deny that phantasmata are present in every case in which phantasia is operative. This suggestion bolsters the idea that, according to Aristotle’s account of veridical perception, we can understand the world as making itself perceptually manifest to the perceiver. (shrink)

Rüdiger Bittner has recently argued against a Kantian ‘maxims account’ of reasons for action. In this paper I argue—against Bittner—that Kantian maxims are not to be understood as reasons for action, but rather as reasons for reasons. On the interpretation presented here, Kantian maxims are the reasons for an agent’s being motivated by whatever more immediate reasons actually motivate her. This understanding of Kantian maxims suggests a recognizably realist Kantian position in ethics.

Since the 1970s, at least, and presumably under the influence of the later Wittgenstein, certain advocates of Aristotle’s ethics have insisted that a proper validation of the virtues of character must proceed only from within, or be internal to, the particular evaluative outlook provided by possession of the virtues themselves. The most influential advocate of this line of thinking is arguably John McDowell, although Rosalind Hursthouse and Daniel C. Russell have also more recently embraced it. Here I consider whether a (...) distinction between the ‘substantive virtues’ and the ‘virtues of will power’ ultimately threatens that way of thinking about Aristotle’s ethics. If so, it would encourage a different reading of Aristotle’s ethics, one that McDowell has described as a “historical monstrosity”. (shrink)

The most long-standing criticism of virtue ethics in its traditional, eudaimonistic variety centers on its apparently foundational appeal to nature in order to provide a source of normativity. This paper argues that a failure to appreciate both the giving and taking of reasons in sustaining an ethical outlook can distort a proper understanding of the available options for this traditional version of virtue ethics. To insist only on giving reasons, without also taking (maybe even considering) the reasons provided by others, (...) displays a sadly illiberal form of prejudice. The paper finds and criticizes such a distortion in Jesse Prinz’s recent discussion of the ‘Normativity Challenge’ to Aristotelian virtue ethics, thus highlighting a common tendency that we can helpfully move beyond. (shrink)

The ‘skill model’ of virtue has received increasing levels of attention over the past decade, at least partly due to its prominence in the work of Julia Annas. Building on this earlier work, some of which is his own, Matt Stichter now delivers a bold and empirically grounded new book, The Skillfulness of Virtue, an extended defense of the skill model of virtue that utilizes the available psychological research on self-regulation and practical expertise. Stichter examines the idea (familiar in antiquity) (...) that the virtues might be analogous to practical skills, and he defends a very strong version of this thesis, that the virtues actually just are a special kind of practical skill. A morally virtuous person is one who achieves expertise in moral skills; and he helpfully extends this empirically grounded thesis beyond the case of ethics, to encompass epistemic virtue as well. Stichter’s book makes a major contribution to virtue theory that will shape future research on the skill model of virtue in philosophy and moral psychology, but also potentially in empirical psychology and other disciplines. (shrink)

Dietrich Bonhoeffer was executed in Flossenbürg concentration camp in Germany in 1945 for being an “upstander” in Rivka Weinberg’s sense. He was an anti-Nazi conspirator, and he and some of his fellow Christians (he was a Lutheran pastor) were hanged in connection with a failed attempt to assassinate Adolph Hitler. Bonhoeffer’s resistance to racist hatred stands in sharp contrast to what he calls “Christian radicalism,” a total withdrawal from or an attempt to “improve” upon God’s creation, something Bonhoeffer characterizes as (...) “hatred” of the world. “When evil becomes powerful in the world,” he wrote, “it infects the Christian, too, with the poison of radicalism” (Bonhoeffer 1955, 87). He presumably had Christian collaboration with Nazi genocide in mind. Today different examples might occur to us. ... (shrink)

We propose a formal framework for interpretable machine learning. Combining elements from statistical learning, causal interventionism, and decision theory, we design an idealised explanation game in which players collaborate to find the best explanation for a given algorithmic prediction. Through an iterative procedure of questions and answers, the players establish a three-dimensional Pareto frontier that describes the optimal trade-offs between explanatory accuracy, simplicity, and relevance. Multiple rounds are played at different levels of abstraction, allowing the players to explore overlapping causal (...) patterns of variable granularity and scope. We characterise the conditions under which such a game is almost surely guaranteed to converge on a optimal explanation surface in polynomial time, and highlight obstacles that will tend to prevent the players from advancing beyond certain explanatory thresholds. The game serves a descriptive and a normative function, establishing a conceptual space in which to analyse and compare existing proposals, as well as design new and improved solutions. (shrink)

Machine learning algorithms may radically improve our ability to diagnose and treat disease. For moral, legal, and scientific reasons, it is essential that doctors and patients be able to understand and explain the predictions of these models. Scalable, customisable, and ethical solutions can be achieved by working together with relevant stakeholders, including patients, data scientists, and policy makers.

Artificial intelligence has historically been conceptualized in anthropomorphic terms. Some algorithms deploy biomimetic designs in a deliberate attempt to effect a sort of digital isomorphism of the human brain. Others leverage more general learning strategies that happen to coincide with popular theories of cognitive science and social epistemology. In this paper, I challenge the anthropomorphic credentials of the neural network algorithm, whose similarities to human cognition I argue are vastly overstated and narrowly construed. I submit that three alternative supervised learning (...) methods—namely lasso penalties, bagging, and boosting—offer subtler, more interesting analogies to human reasoning as both an individual and a social phenomenon. Despite the temptation to fall back on anthropomorphic tropes when discussing AI, however, I conclude that such rhetoric is at best misleading and at worst downright dangerous. The impulse to humanize algorithms is an obstacle to properly conceptualizing the ethical challenges posed by emerging technologies. (shrink)

In this paper I draw on some of the work of John McDowell in order to develop a realist account of normative reasons for action. On the view defended here, there can be correct moral judgments that capture the reasons there are for acting in certain ways; and the reasons themselves are just some of the morally relevant facts of the situation about which the judgment is made. Establishing this account relies crucially, I argue, on an appeal to substantive ethical (...) theory, to a theory that allows for the attribution of truth to the judgments in question. The account defended here can in fact be equally well supported by ethical theories as otherwise diverse as those of Aristotle and Kant. The resulting account is a version of moral realism, but one that is not committed to defending a realist account of the nature of moral value. (shrink)

A CHOICE Outstanding Academic Title 2022 | The Moral Psychology of Hate provides the first systematic introduction to the moral psychology of hate, compiling specially commissioned essays by an international team of scholars with a wide range of disciplinary orientations. In light of the recent revival of interest in emotions in academic philosophy and the current social and political interest in hate, this volume provides arguments for and against the value of hate through a combination of empirical and philosophical methods. (...) The authors examine hate not merely as a destructive feeling but as an emotion of great moral significance that illuminates how we understand each other and ourselves. The book will be of major interest to anyone concerned with the dynamics and the moral and political implications of this most powerful of human emotions. (shrink)

This paper concerns the prospects for an internal validation of the Aristotelian virtues of character. With respect to the more contentious trait of patriotism, this approach for validating some specific trait of character as a virtue of character provides a plausible and nuanced Aristotelian position that does not fall neatly into any of the categories provided by a recent mapping of the terrain surrounding the issue of patriotism. According to the approach advocated here, patriotism can plausibly, though qualifiedly, be defended (...) as a virtue, by stressing its similarities to another loyalty-exhibiting trait about which Aristotle has quite a bit to say: the virtue of friendship. (shrink)

Necessity and sufficiency are the building blocks of all successful explanations. Yet despite their importance, these notions have been conceptually underdeveloped and inconsistently applied in explainable artificial intelligence (XAI), a fast-growing research area that is so far lacking in firm theoretical foundations. Building on work in logic, probability, and causality, we establish the central role of necessity and sufficiency in XAI, unifying seemingly disparate methods in a single formal framework. We provide a sound and complete algorithm for computing explanatory factors (...) with respect to a given context, and demonstrate its flexibility and competitive performance against state of the art alternatives on various tasks. (shrink)

‘Greek Ethics’, an undergraduate class taught by the British moral philosopher N. J. H. Dent, introduced this reviewer to the ethical philosophy of ancient Greece. The class had a modest purview—a sequence of Socrates, Plato, and Aristotle—but it proved no less effective, in retrospect, than more synoptic classes for having taken this apparently limited and (for its students and academic level) appropriate focus. This excellent Companion will now serve any such class extremely well, allowing students a broader exposure than that (...) traditional sequence, without sacrificing the class’s circumscribed focus. The eighteen chapters encompass some of what went before, and surprisingly much of what came after, those three central philosophers—including, for instance, a discussion of Plotinus and his successors, as well as a discussion of Horace. The book will therefore be useful in many different types of class on ethical philosophy in the ancient world. This Companion will be useful not only to students, but also to at least three further groups: specialists in ancient Greek philosophy (since some contributors advance significant new positions, e.g. R. Kamtekar on Plato’s ethical psychology and D. Charles on Aristotle’s ‘ergon argument’ as already implicitly invoking ‘to kalon’); scholars working in academic subjects adjacent to ancient Greek philosophy; and contemporary moral philosophers. (shrink)

Philosophical lessons come in many different shapes and sizes. Some lessons are big, some are small. Some lessons go deep and have a big impact, some are shallow and have almost none. Some lessons are not really philosophical at all or would not really be lessons for an audience of academic philosophers. I mention these truisms not to disparage this informative book on 'moral OCD' (moral obsessive-compulsive disorder, or 'Scrupulosity') but rather to emphasize how difficult it can be to discern (...) the book's intended audience, given its interdisciplinary aims and structure. That question is never explicitly addressed (it is admittedly a slim book, slimmer than it appears), but the question has consequences for how to think about the book's ultimate value, and for whom. The book might attract two groups in particular: philosophers working on the nature of responsibility (the subject of the book's longest chapter) and psychiatric researchers or mental health professionals interested in moral philosophy and the philosophy of mental illness. I will return to what moral philosophers can learn from moral OCD, but there will be spoilers. (shrink)

In this ambitious first book, Erick Raphael Jiménez argues that a good model for understanding Aristotle’s concept of mind (nous) lies in Aristotle’s account of the perception of time. This “time-perception model” of mind and its activity, thinking, bridges a gap between Jiménez’s unorthodox readings of Aristotelian mind and its objects. The book will attract the interest of specialists in Aristotle’s psychology, as well as other scholars interested in Aristotle’s concept of mind and its influence, for instance, theologians interested in (...) Aristotle’s tantalizing discussion of active or maker mind in De Anima 3.5 (DA). (shrink)

It is a personal matter, a point of autobiography, but it illustrates something that beats in the heart of Cillian McBride’s compact and quietly ambitious book, that I cannot myself choose to value, that I cannot myself choose to esteem, racial or homophobic bigotry. Hence bigots cannot justifiably demand that I recognize the alleged value of their bigotry; nor can they demand such recognition from society more generally, esteem being tied in this way to sincere evaluation. Although a failure to (...) obtain social recognition might result in a loss of self-esteem for some bigots, and although this would in a way be bad, this negative result would be, in another way, simply too bad for bigotry. (shrink)

Linda Trinkaus Zagzebski believes that a comprehensive moral theory can be constructed by identifying moral exemplars and by investigating (to put it very roughly) what it is that makes them tick. We identify moral exemplars by direct reference to persons we admire "upon reflection." Moral exemplars are persons like that. Two emotions will play a central role in this type of moral theory: admiration, and its opposite, contempt. Zagzebski's theory proceeds by rough analogy with a physical theory that identifies instances (...) of water and then goes on to investigate the physical make-up of the natural kind, water. But an even better comparison, as she says, is to a community of linguistic users which identifies various instances of tigers, say, and then goes on to investigate the (possibly evolving) referent of the species-term "tiger." Zagzebski provides an engaging, illuminating, and deeply human discussion of how the details of this exemplarist approach, with its investigation into the psychological make up of moral exemplars, might be developed. (shrink)

I briefly discuss the Gettier Problem, problems with the justified theory of true belief, and offer support for Feldman's concept of no false grounds.

This volume initiates a welcome new Oxford Studies series based on the annual meeting of the Arizona Workshop in Normative Ethics, organized by Mark Timmons. The back matter indicates that the series is a place where, "Leading philosophers present original contributions to our understanding of a wide range of moral issues and positions." But Timmons himself says more accurately, it seems, that the series aims to provide "some of the best contemporary work in the field of contemporary ethical theory" (p. (...) ix). In what follows I focus on only two of the individual papers; but first I want to make some remarks by way of overview and introduction. (shrink)

What might it mean to read video games as a source for critical theological reflection? This project explores the extent to which FromSoftware’s 2015 classic Bloodborne can be read in just this way for at least two reasons. Firstly, the game makes visible foundational but often taken-for-granted Christian themes, as well as their internal paradoxes. Secondly, Bloodborne’s gameplay is structured through these themes in ways that invite the player to take on a mode of theological reflection which allows them to (...) think creatively beyond the conditions giving rise to these paradoxes. (shrink)

ABSTRACT In order to explore what it means to pursue philosophical investigations for theological reasons, this paper argues that Ludwig Wittgenstein continues and corrects Pseudo-Denys’ project in The Divine Names. I first argue that The Divine Names should be interpreted as attempting to render human thought transparent to the divine by relativizing our concepts. The success of this project is compromised because the concept of ‘unity’ is not relativized. I then develop the claim that Wittgenstein does relativize unity in a (...) similar way and for similar religious reasons to Pseudo-Denys. As such, he can be read as continuing and correcting the Pseudo-Dionysian project. I conclude by reflecting on several of this argument’s implications for the relationship between philosophy and Christian systematic theology. (shrink)

Two perennial doubts can linger in the minds of people working in the history of philosophy. Those who approach philosophical problems in a systematic, analytic spirit may come to think that work in the history of philosophy fails to amount to genuine philosophy; and those who are more historically-minded may come to think that the very same work fails to amount to genuine history. In this rich and rewarding new book, Allen Wood nevertheless succeeds in delivering a defense of Kantian (...) ethics that should satisfy, in terms of its philosophical credentials, any philosopher interested in ethics; and it should also satisfy, in terms of its historical credentials, anyone interested in the ethical thought of Immanuel Kant himself. (shrink)

Simon Blackburn has not shied away from the use of vivid imagery in developing, over a long and prolific career, a large-scale philosophical vision. Here one might think, for instance, of ‘Practical Tortoise Raising’ or ‘Ramsey's Ladder’ or ‘Frege's Abyss’. Blackburn develops a ‘quasi-realist’ account of many of our philosophical and everyday commitments, both theoretical (e.g., modality and causation) and practical (e.g., moral judgement and normative reasons). Quasi-realism aims to provide a naturalistic treatment of its targeted phenomena while earning the (...) right to deploy all of the ‘trappings’ of realism—i.e., while eschewing any idea that our normal thought and talk about such phenomena are pervasively in error. The quasi-realist project is that of explaining how (as Huw Price puts it here) ‘the folk come to “talk the realist talk” without committing ourselves—us theorists, as it were—to “walking the metaphysical walk”’ (p. 136). Quasi-realism, too, can speak of truth, facts, properties, belief, knowledge, and so on. The imagery in this collection also abounds, though, in capturing a different view of quasi-realism: No fewer than three of the contributors picture Blackburn as wanting to have his cake and eat it too (Louise Antony asking, in addition, ‘Who doesn't? It's cake’ [p. 19]). (shrink)

Hortense Spillers asserts the imperative for black writers to reconfigure the languages they inherit. One way of doing so is to craft counter-myths against dominative mythologies. Spillers casts myth as an integration of form and concept which overdetermines the significance of what it is used to talk about. One crucial effect of America’s racialising mythos has been to deny black women the ability to determine that significance. She then describes how this mythos is crafted through a double wounding that creates (...) at least two ‘interstices’—first between home and market, then between blackness and humanity—which are covered up by mythological terms. Finally, Spillers shows how counter-mythologies can be crafted by speaking from within these interstices to reconfigure the conditions of possibility governing meaningful speech, taking the 19th- century African-American preaching tradition as her example. The article concludes by reflecting on what it might mean to practice Christian theology as counter-mythology in light of Spillers’ work through a reading of Edwidge Danticat’s The Dew Breaker. (shrink)

Theorists such as Stuart Hall have problematised the idea that identity is something that remains essentially the same across time. Since doctrine has been cast as that which safeguards Christian identity, this provokes the question: what role can doctrine play if this is the case? Critiquing George Lindbeck's The Nature of Doctrine in light of Kathryn Tanner's work on rules suggests that doctrine cannot regulate, constitute or generate the necessary conditions for Christian identity. Doctrine can, however, still play a role (...) in generating Christian meaning without regulating identity by determining how concepts are formed in Christian community. (shrink)

I explore the political, economic, and cultural consequences of globalization of the reduction of space in the world. This work compares and contrasts the philosophical implications Jameson (and Marx) and Sloterdijk (with Heidegger) of globalization. The film 2001: A Space Odyssey is discussed as a metaphor for the cultural narratives Jameson and Sloterdijk provide.

The modern abundance and prominence of data has led to the development of “data science” as a new field of enquiry, along with a body of epistemological reflections upon its foundations, methods, and consequences. This article provides a systematic analysis and critical review of significant open problems and debates in the epistemology of data science. We propose a partition of the epistemology of data science into the following five domains: (i) the constitution of data science; (ii) the kind of enquiry (...) that it identifies; (iii) the kinds of knowledge that data science generates; (iv) the nature and epistemological significance of “black box” problems; and (v) the relationship between data science and the philosophy of science more generally. (shrink)

I briefly compare and contrast the philosophy of Confucius as written in the I Ching and Lao Tzu's philosophy presented in the Tao Te Ching.

Discovering high-level causal relations from low-level data is an important and challenging problem that comes up frequently in the natural and social sciences. In a series of papers, Chalupka etal. (2015, 2016a, 2016b, 2017) develop a procedure forcausal feature learning (CFL) in an effortto automate this task. We argue that CFL does not recommend coarsening in cases where pragmatic considerations rule in favor of it, and recommends coarsening in cases where pragmatic considerations rule against it. We propose a new technique, (...) pragmatic causal feature learning (PCFL), which extends the original CFL algorithm in useful and intuitive ways. We show that PCFL has the same attractive measure-theoretic properties as the original CFL algorithm. We compare the performance of both methods through theoretical analysis and experiments. (shrink)

I briefly discuss and support the concept of social utility proposed by Hume.

Recent years have seen a surge in online collaboration between experts and amateurs on scientific research. In this article, we analyse the epistemological implications of these crowdsourced projects, with a focus on Zooniverse, the world’s largest citizen science web portal. We use quantitative methods to evaluate the platform’s success in producing large volumes of observation statements and high impact scientific discoveries relative to more conventional means of data processing. Through empirical evidence, Bayesian reasoning, and conceptual analysis, we show how information (...) and communication technologies enhance the reliability, scalability, and connectivity of crowdsourced e-research, giving online citizen science projects powerful epistemic advantages over more traditional modes of scientific investigation. These results highlight the essential role played by technologically mediated social interaction in contemporary knowledge production. We conclude by calling for an explicitly sociotechnical turn in the philosophy of science that combines insights from statistics and logic to analyse the latest developments in scientific research. (shrink)

I briefly discuss the issues with Aristotle's concept of balance and justice and contrast this with the concept of liberty argued by Camus.

I briefly discuss the philosophical reasons for preferring the future over the present.

I briefly discuss the problems of Chisholm's entia successiva--the mind and body being successive parts of a machine.

I. EXECUTIVE SUMMARY The MRCT Center Post-trial Responsibilities: Continued Access to an Investigational Medicine Framework outlines a case-based, principled, stakeholder approach to evaluate and guide ethical responsibilities to provide continued access to an investigational medicine at the conclusion of a patient’s participation in a clinical trial. The Post-trial Responsibilities (PTR) Framework includes this Guidance Document as well as the accompanying Toolkit. A 41-member international multi-stakeholder Workgroup convened by the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard University (...) (MRCT Center) developed this Guidance and Toolkit. Project Motivation A number of international organizations have discussed the responsibilities stakeholders have to provide continued access to investigational medicines. The World Medical Association, for example, addressed post-trial access to medicines in Paragraph 34 of the Declaration of Helsinki (WMA, 2013): “In advance of a clinical trial, sponsors, researchers and host country governments should make provisions for post-trial access for all participants who still need an intervention identified as beneficial in the trial. This information must also be disclosed to participants during the informed consent process.” This paragraph and other international guidance documents converge on several consensus points: • Post-trial access (hereafter referred to as “continued access” in this Framework [for terminology clarification – see definitions]) is the responsibility of sponsors, researchers, and host country governments; • The plan for continued access should be determined before the trial begins, and before any individual gives their informed consent; • The protocol should delineate continued access plans; and • The plan should be transparent to potential participants and explained during the informed consent process. -/- However, there is no guidance on how to fulfill these responsibilities (i.e., linking specific responsibilities with specific stakeholders, conditions, and duration). To fill this gap, the MRCT Center convened a working group in September of 2014 to develop a framework to guide stakeholders with identified responsibilities. This resultant Framework sets forth applicable principles, approaches, recommendations and ethical rationales for PTR regarding continued access to investigational medicines for research participants. (shrink)

http://www.slimmerbetteryou.com Talks about weight loss principles and facts that need to be understood perfectly well.

In Philosophy and Technology 36, David Watson discusses the epistemological and metaphysical implications of unsupervised machine learning (ML) algorithms. Watson is sympathetic to the epistemological comparison of unsupervised clustering, abstraction and generative algorithms to human cognition and sceptical about ML’s mechanisms having ontological implications. His epistemological commitments are that we learn to identify “natural kinds through clustering algorithms”, “essential properties via abstraction algorithms”, and “unrealized possibilities via generative models” “or something very much like them.” The same issue contains (...) a commentary on Watson’s paper in which Tom Sterkenburg fiercely opposes the epistemological claim that clustering algorithms can identify natural kinds. Sterkenburg argues there’s nothing about clustering arguments themselves that enables natural kind identification. What’s at stake in the Watson-Sterkenburg debate is whether it is possible for clustering algorithms to identify natural kinds and whether they underly human identification of natural kinds. My contribution to the Watson-Sterkenburg debate is twofold. First, I argue Sterkenburg’s criticism of Watson’s claim is too severe because it denies any clustering algorithm to identify any natural kind. Secondly, I argue Watson’s reply overestimates both clustering algorithms’ and humans’ access to natural kinds and his claim has to be restricted accordingly to ‘We identify kinds via clustering algorithms, or something very much like them’. (shrink)