Considerable variation exists not only in the kinds of transposable elements (TEs) occurring within the genomes of different species, but also in their abundance and distribution. Noting a similarity to the assortment of organisms among ecosystems, some researchers have called for an ecological approach to the study of transposon dynamics. However, there are several ways to adopt such an approach, and it is sometimes unclear what an ecological perspective will add to the existing co-evolutionary framework for explaining transposon-host interactions. This (...) review aims to clarify the conceptual foundations of transposon ecology in order to evaluate its explanatory prospects. We begin by identifying three unanswered questions regarding the abundance and distribution of TEs that potentially call for an ecological explanation. We then offer an operational distinction between evolutionary and ecological approaches to these questions. By determining the amount of variance in transposon abundance and distribution that is explained by ecological and evolutionary factors, respectively, it is possible empirically to assess the prospects for each of these explanatory frameworks. To illustrate how this methodology applies to a concrete example, we analyzed whole-genome data for one set of distantly related mammals and another more closely related group of arthropods. Our expectation was that ecological factors are most informative for explaining differences among individual TE lineages, rather than TE families, and for explaining their distribution among closely related as opposed to distantly related host genomes. We found that, in these data sets, ecological factors do in fact explain most of the variation in TE abundance and distribution among TE lineages across less distantly related host organisms. Evolutionary factors were not significant at these levels. However, the explanatory roles of evolution and ecology become inverted at the level of TE families or among more distantly related genomes. Not only does this example demonstrate the utility of our distinction between ecological and evolutionary perspectives, it further suggests an appropriate explanatory domain for the burgeoning discipline of transposon ecology. The fact that ecological processes appear to be impacting TE lineages over relatively short time scales further raises the possibility that transposons might serve as useful model systems for testing more general hypotheses in ecology. (shrink)

Purpose This systematic review aims to identify factors that influence parents’ decisions regarding pediatric diagnostic and predictive genetic testing (DT/PT). Factors are integrated into a conceptual model of decision-making. Implications for genetic counseling, research, and ethics are derived. Methods PubMed, PsychInfo, WebofScience and references of related reviews were searched for original publications between 2000 and 2023. Extracted factors were categorized into an existing model. Results Of 5843 publications, 56 met inclusion criteria. The included studies differentiate between DT, traditional, and expanded (...) PT and describe factors impacting parental decisions on both to have the child genetically tested and to be informed about additional findings. Factors included: 1. benefits/hopes, 2. worries/concerns, 3. values and beliefs, 4. individual circumstances, and 5. emotional states. Conclusion Our work extends an existing empirical decision model of family decisions about genome sequencing to genetic testing in pediatrics in general, adding the categories “individual circumstances” and “emotional states”. The factors can be further integrated into the Health Belief Model; the importance of emotional states is reflected in dual-process theories, such as Fuzzy Trace Theory. Research is required on emotional states, differences between DT and PT, parents’ decisions about result disclosure, and dyadic variables as decision-making predictors. (shrink)

Driven by technological innovations, newborn screening (NBS) panels have been expanded and the development of genomic NBS pilot programs is rapidly progressing. Decisions on disease selection for NBS are still based on the Wilson and Jungner (WJ) criteria published in 1968. Despite this uniform reference, interpretation of the WJ criteria and actual disease selection for NBS programs are highly variable. A systematic literature search [PubMED search “Wilson” AND “Jungner”; last search 16.07.22] was performed to evaluate the applicability of the WJ (...) criteria for current and future NBS programs and the need for adaptation. By at least two reviewers, 105 publications (systematic literature search, N = 77; manual search, N = 28) were screened for relevant content and, finally, 38 publications were evaluated. Limited by the study design of qualitative text analysis, no statistical evaluation was performed, but a structured collection of reported aspects of criticism and proposed improvements was instead collated. This revealed a set of general limitations of the WJ criteria, such as imprecise terminology, lack of measurability and objectivity, missing pediatric focus, and absent guidance on program management. Furthermore, it unraveled specific aspects of criticism on clinical, diagnostic, therapeutic, and economical aspects. A major obstacle was found to be the incompletely understood natural history and phenotypic diversity of rare diseases prior to NBS implementation, resulting in uncertainty about case definition, risk stratification, and indications for treatment. This gap could be closed through the systematic collection and evaluation of real-world evidence on the quality, safety, and (cost-)effectiveness of NBS, as well as the long-term benefits experienced by screened individuals. An integrated NBS public health program that is designed to continuously learn would fulfil these requirements, and a multi-dimensional framework for future NBS programs integrating medical, ethical, legal, and societal perspectives is overdue. (shrink)

Neo-Russellians like Salmon and Braun hold that: the semantic contents of sentences are structured propositions whose basic components are objects and properties, names are directly referential terms, and a sentence of the form ‘n believes that S’ is true in a context c iff the referent of the name n in c believes the proposition expressed by S in c. This is sometimes referred to as ‘the Naive Russellian theory’. In this talk, I will discuss the Naive Russellian theory primarily (...) in connection with a problem known as Schiffer’s puzzle. Schiffer first presented the puzzle as an argument against the Naive Russellian theory. Schiffer’s argument proceeds in two steps. In step one, Schiffer argues that the Naive Russellian theory is committed to two principles regarding de re belief; the special-case consequence and Frege’s constraint. Then, in step two, Schiffer argues that the special-case consequence is not consistent with Frege’s constraint. Salmon and Braun reply to Schiffer’s argument that although the Naive Russellian theory is committed to Frege’s constraint, it is not committed to the special-case consequence. However, in this paper, I will argue with a new Schiffer-case that even if the Naive Russellian theory is not committed to the special-case consequence, it is still not consistent with Frege’s constraint. Concluding, I will discuss the possibility to reject Frege’s constraint within the Naive Russellian theory. (shrink)

Study represents an application of the neutrosophic method, for solving the contradiction between communication and information. In addition, it recourse to an appropriate method of approaching the contradictions: Extensics, as the method and the science of solving the contradictions. The research core is the reality that the scientific research of communication-information relationship has reached a dead end. The bivalent relationship communicationinformation, information-communication has come to be contradictory, and the two concepts to block each other. After the critical examination of conflicting (...) positions expressed by many experts in the field, the extensic and inclusive hypothesis is issued that information is a form of communication. The object of communication is the sending of a message. The message may consist of thoughts, ideas, opinions, feelings, beliefs, facts, information, intelligence or other significational elements. When the message content is primarily informational, communication will become information or intelligence. The arguments of supporting the hypothesis are: a) linguistic (the most important being that there is "communication of information" but not "information of communication"; also, it is clarified and reinforced the over situated referent, that of the communication as a process), b) systemic-procedural (in the communication system is developing an information system; the informing actant is a type of communicator, the information process is a communication process), c) practical (the delimitation eliminates the efforts of disparate and inconsistent understanding of the two concepts), d) epistemological arguments (the possibility of intersubjective thinking of reality is created), linguistic arguments, e) logical and realistic arguments (it is noted the situation that allows to think coherently in a system of concepts - derivative series or integrative groups) f) and arguments from historical experience (the concept of communication has temporal priority, it appears 13 times in Julius Caesar’s writings ). In an axiomatic conclusion, the main arguments are summarized in four axioms: three are based on the pertinent observations of specialists, and the fourth is a relevant application of Florentin Smarandache’s neutrosophic theory. (shrink)

Bios Philosophos. Philosophy in Ancient Greek Biography (Brepols, 2016), organized by Mauro Bonazzi and Stefan Schorn, delivers deep and wide tours through the philosophical aspects of Greek biographical production. On the one hand, it does not concentrate only on the later periods of Greek philosophy, when biographical production abounded; instead, it goes all the way back to the fourth century BCE, when biographical texts were fragmentary and mingled with other styles. On the other, it tries to unveil the philosophical (...) motives in authors' works who tend to be disregarded as historians, biographers, hagiographers, or even as mere fans of the most prominent figures of their own schools. -/- In our review, we will attempt to give a brief account of the ten articles that make up this volume, which, in turn, will hopefully provide an overview of the different connections between the biographies and biographers and their philosophical motives. (shrink)

The aim of my paper is to describe and evaluate different conceptions of holism in Ludwig Wittgenstein’s Tractatus Logico-Philosophicus. I distinguish three readings of holistic elements in this work: i) Minimal Holism (E. Anscombe, M. Black, D. Pears); ii) Moderate Holism (J. Conant, C. Diamond, G. Ryle); and iii) Radical Holism (G. Bar-Elli, M. Kremer, P. Livingston). The conclusion is that the most viable option is Moderate Holism since it embraces the logico-syntactical notion of use, rejects an anachronistic interpretation (...) of Tractatarian ontology and allows us to see that the holistic elements are complementary to the initial atomism of the work. Moreover, I point to the consequences of the topic for the overall reading of Wittgenstein’s early and late work. (shrink)

Revista Cunoașterea Științifică este o publicație trimestrială din domeniile științei și filosofiei, și domenii conexe de studiu și practică. -/- Cuprins: -/- EDITORIAL / EDITORIAL -/- Nicolae SFETCU From Primitive Instincts to Advanced Cognition: The Evolution of Human Intelligence De la instinctele primitive la cunoașterea avansată: evoluția inteligenței umane -/- ȘTIINȚE NATURALE / NATURAL SCIENCE -/- Nicolae SFETCU Discovery of Astatine by Horia Hulubei Descoperirea astatinului de Horia Hulubei -/- Lucian Ștefan COZMA, Cosmin Vasile ȚENU, Daniela Georgiana GOLEA The Romteleghid (...) project between legend and historical reality Proiectul Romteleghid între legendă și realitate istorică -/- Lucian Ștefan COZMA, Daniela Georgiana GOLEA, Cosmin Vasile ȚENU Inexpensive and environmentally friendly fuel blend for catalytic combustion in power boilers and internal combustion engines – a solution for Europe Amestec de combustibil ieftin și ecologic destinat arderii catalitice în cazanele termoenergetice și motoarele de ardere internă, o soluție pentru Europa -/- ȘTIINȚE SOCIALE / SOCIAL SCIENCE Mădălina MIRON Putinjugend: The Pro-Kremlin Youth Movement Nashi Putinjugend: Mișcarea de tineret pro-Kremlin Nashi -/- Alexandru Ș. BOLOGA and Ana-Maria GRĂMESCU Tropaeum Augusti (France) and Tropaeum Traiani (Romania): A Comparative Study Tropaeum Augusti (Franța) și Tropaeum Traiani (România): Un studiu comparativ -/- Mark C. LUKÁCS Innovative Advertising Campaigns for Cultural Institutions: Exploring Public-Private Partnership Opportunities and Framework Campanii de publicitate inovatoare pentru instituții culturale: Explorarea oportunităților și cadrului de parteneriat public-privat -/- ȘTIINȚE FORMALE / FORMAL SCIENCE -/- Valentin IONESCU In a Universe where space and time are discrete, the maximum possible speed is finite. Lorentz contraction in a discrete universe Într-un Univers în care spațiul și timpul sunt discrete, viteza maximă posibilă este finită. Contracția Lorentz și dilatarea timpului într-un univers discret -/- FILOSOFIE / PHILOSOPHY -/- Dumitru MAZÎLU The subsequent development of the term canon in the early Christian centuries Dezvoltarea subsecventă a termenului de canon în primele secole creștine -/- ISSN 2821-8086 ISSN-L 2821-8086, DOI: 10.58679/CS67492. (shrink)

This tenth volume of Collected Papers includes 86 papers in English and Spanish languages comprising 972 pages, written between 2014-2022 by the author alone or in collaboration with the following 105 co-authors (alphabetically ordered) from 26 countries: Abu Sufian, Ali Hassan, Ali Safaa Sadiq, Anirudha Ghosh, Assia Bakali, Atiqe Ur Rahman, Laura Bogdan, Willem K.M. Brauers, Erick González Caballero, Fausto Cavallaro, Gavrilă Calefariu, T. Chalapathi, Victor Christianto, Mihaela Colhon, Sergiu Boris Cononovici, Mamoni Dhar, Irfan Deli, Rebeca Escobar-Jara, Alexandru Gal, N. (...) Gandotra, Sudipta Gayen, Vassilis C. Gerogiannis, Noel Batista Hernández, Hongnian Yu, Hongbo Wang, Mihaiela Iliescu, F. Nirmala Irudayam, Sripati Jha, Darjan Karabašević, T. Katican, Bakhtawar Ali Khan, Hina Khan, Volodymyr Krasnoholovets, R. Kiran Kumar, Manoranjan Kumar Singh, Ranjan Kumar, M. Lathamaheswari, Yasar Mahmood, Nivetha Martin, Adrian Mărgean, Octavian Melinte, Mingcong Deng, Marcel Migdalovici, Monika Moga, Sana Moin, Mohamed Abdel-Basset, Mohamed Elhoseny, Rehab Mohamed, Mohamed Talea, Kalyan Mondal, Muhammad Aslam, Muhammad Aslam Malik, Muhammad Ihsan, Muhammad Naveed Jafar, Muhammad Rayees Ahmad, Muhammad Saeed, Muhammad Saqlain, Muhammad Shabir, Mujahid Abbas, Mumtaz Ali, Radu I. Munteanu, Ghulam Murtaza, Munazza Naz, Tahsin Oner, ‪Gabrijela Popović‬‬‬‬‬, Surapati Pramanik, R. Priya, S.P. Priyadharshini, Midha Qayyum, Quang-Thinh Bui, Shazia Rana, Akbara Rezaei, Jesús Estupiñán Ricardo, Rıdvan Sahin, Saeeda Mirvakili, Said Broumi, A. A. Salama, Flavius Aurelian Sârbu, Ganeshsree Selvachandran, Javid Shabbir, Shio Gai Quek, Son Hoang Le, Florentin Smarandache, Dragiša Stanujkić, S. Sudha, Taha Yasin Ozturk, Zaigham Tahir, The Houw Iong, Ayse Topal, Alptekin Ulutaș, Maikel Yelandi Leyva Vázquez, Rizha Vitania, Luige Vlădăreanu, Victor Vlădăreanu, Ștefan Vlăduțescu, J. Vimala, Dan Valeriu Voinea, Adem Yolcu, Yongfei Feng, Abd El-Nasser H. Zaied, Edmundas Kazimieras Zavadskas.‬‬. (shrink)

Revista Cunoașterea Științifică este o publicație trimestrială din domeniile științei și filosofiei, și domenii conexe de studiu și practică. -/- Cuprins: -/- EDITORIALS / EDITORIALE -/- Nicolae Sfetcu Apărarea împotriva atacurilor cibernetice avansate Defense Against Advanced Cyber Attacks -/- Nicolae Sfetcu Ce este inteligența? What is intelligence? -/- Nicolae Sfetcu De la instinctele primitive la cunoașterea avansată: evoluția inteligenței umane From Primitive Instincts to Advanced Cognition: The Evolution of Human Intelligence -/- Nicolae Sfetcu Falsificabilitatea lui Imre Lakatos în contextul programelor (...) științifice de cercetare The Falsifiability of Imre Lakatos in the Context of the Scientific Research Programs -/- NATURAL SCIENCE / ȘTIINȚE NATURALE -/- Nicolae Sfetcu Cosmological Tests Based on General Relativity for Gravity Teste cosmologice bazate pe relativitatea generală pentru gravitație -/- Ștefan-Daniel Florea Integrarea tehnologiei moderne în gestionarea riscului seismic Integrating modern technology into seismic risk management -/- Nicolae Sfetcu Epistemology of Loop Quantum Gravity in the Context of Canonical Quantum Gravity Epistemologia gravitației cuantice în buclă în contextul gravitației cuantice canonice -/- Valentin Ionescu Constante universale, energia vidului și creșterea în timp a găurilor negre în Modelul Big Bangului Rece Universal constants, vacuum energy and the growth of black holes over time in the Cold Big Bang Model -/- Nicolae Sfetcu Discovery of Astatine by Horia Hulubei Descoperirea astatinului de Horia Hulubei -/- Lucian Ștefan Cozma, Cosmin Vasile Țenu, Daniela Georgiana Golea Proiectul Romteleghid între legendă și realitate istorică The Romteleghid project between legend and historical reality -/- Lucian Ștefan Cozma, Daniela Georgiana Golea, Cosmin Vasile Țenu Amestec de combustibil ieftin și ecologic destinat arderii catalitice în cazanele termoenergetice și motoarele de ardere internă, o soluție pentru Europa Inexpensive and environmentally friendly fuel blend for catalytic combustion in power boilers and internal combustion engines - a solution for Europe -/- Nicolae Sfetcu The Evolution of Human Intelligence Throughout a Person's Life - A Lifelong Journey Evoluția inteligenței umane de-a lungul vieții unei persoane - O călătorie pe tot parcursul vieții -/- Lucian Ștefan Cozma, Daniela Georgiana Golea, Cosmin Vasile Țenu Utilizarea bremsstrahlung inversat în obținerea fuziunii nucleare controlate The use of inverted bremsstrahlung in achieving controlled nuclear fusion -/- Adrian Klein Can Extended Human Genome Explain Personality Structures? Poate genomul uman extins să explice structurile personalității? -/- Lucian Ștefan Cozma, Daniela Georgiana Golea Potențiala contribuție a inginerului și inventatorului român George „Gogu” Constantinescu în edificarea Castelului Peleș prin elaborarea teoriei moderne a betonului armat The potential contribution of the Romanian engineer and inventor George "Gogu" Constantinescu in the construction of Peleș Castle by developing the modern theory of reinforced concrete -/- Ioan Vasile Buiu, Bogdan Boreschievici Un submarin pierdut în istorie A Submarine Lost in History -/- SOCIAL SCIENCE / ȘTIINȚE SOCIALE -/- Dan D. Farcaș Câteva opinii privind etnogeneza românilor (2) Some opinions regarding the ethnogenesis of the Romanians (2) -/- Aliona Rozovel UTA Găgăuzia de jure parte integrantă și inalienabilă a Republicii Moldova, de facto tinde spre separatism UTA Gagauzia, de jure an integral and inalienable part of the Republic of Moldova, de facto tends towards separatism -/- Nicolae Sfetcu Provocări și tendințe în războiul electronic – Războiul asimetric Challenges and Trends in Electronic Warfare – Asymmetric Warfare -/- Mădălina Miron Putinjugend: The Pro-Kremlin Youth Movement Nashi Putinjugend: Mișcarea de tineret pro-Kremlin Nashi -/- Alexandru Ș. Bologa; Ana-Maria Grămescu Tropaeum Augusti (France) and Tropaeum Traiani (Romania): A Comparative Study Tropaeum Augusti (Franța) și Tropaeum Traiani (România): Un studiu comparativ -/- Mark C. Lukács Campanii de publicitate inovatoare pentru instituții culturale: Explorarea oportunităților și cadrului de parteneriat public-privat Innovative Advertising Campaigns for Cultural Institutions: Exploring Public-Private Partnership Opportunities and Framework -/- Ana-Maria Perța Information sabotage in the context of the communist regime. Case study on communist informers Sabotajul informațional în contextul regimului comunist. Studiu de caz despre informatorii comuniști -/- Manuela Vasilica Tunca, Alina Mihaela Frățică Dragomir, Raluca Mihaela Rădulescu The Implementation and Benefits of Telework in Various Sectors: Reality or Rhetoric? Implementarea și beneficiile telemuncii în diverse sectoare: realitate sau retorică? -/- Alba Iulia Catrinel Popescu, Laura Ungureanu Un personaj istoric controversat al anilor de cumpănă 1940: generalul de corp de armată Aurel Aldea A Controversial Historical Figure of the 1940s: Army Corps General Aurel Aldea -/- FORMAL SCIENCE / ȘTIINȚE FORMALE -/- Constantin Pomparău Ce este ipoteza Riemann și de ce nu poate fi demonstrată What is the Riemann hypothesis and why it cannot be proved -/- Ana Denisa Cutean, Iulia Denisa Moga Contabilitatea activelor de infrastructură Accounting for infrastructure assets -/- Iulia Denisa Moga Tehnica abordării prin cost: evaluarea construcțiilor The technique of the cost approach: construction evaluation -/- Nicolae Sfetcu Apărarea împotriva atacurilor cibernetice prin învățarea automată Defending Against Cyber Attacks Through Machine Learning -/- Dumitru Mazilu Despre unele prevederi canonice și civile privind gestionarea actuala a bunurilor bisericești parohiale About some canonical and civil provisions regarding the current management of parish church assets -/- Alina Mihaela Frătică-Dragomir The Concept of Electronic Pensioner in Some Countries Versus Romania Conceptul de pensionar electronic în unele țări versus România -/- Andreea Teodora Iacob Phasing the COVID-19 Pandemic in Romania. Analysis Based on Social Distancing Measures Etapizarea pandemiei de COVID-19 în România. Analiza bazată pe măsurile de distanțare socială -/- Bogdan Boreschievici Castele în Spania Castles in Spain -/- PHILOSOPHY / FILOSOFIE -/- Nicolae Sfetcu The Republic of Plato: A Philosophical Odyssey Republica lui Platon: o odisee filosofică -/- Tănase Tiberiu, Ovidiu Boureanu Intelligence–ul ca domeniu al cunoașterii Intelligence as a Field of Knowledge -/- Dumitru Mazîlu Dezvoltarea subsecventă a termenului de canon în primele secole creștine The subsequent development of the term canon in the early Christian centuries -/- Valentin Ionescu S-ar putea să nu existe infinitul, decât în nostalgia noastră după starea originară, pierdută, din Grădina Edenului Infinity may not exist except in our nostalgia for our original state, lost Garden of Eden -/- ISSN 2971 – 9070 ISSN-L 2821 – 8086, DOI: 10.58679/CS19653. (shrink)

Science and valuation — remarks about the condition of philosophical re ection on science this text is an attempt at a more general look at twentieth‐century philosophical re ection on science conceived as persistent trials to eliminate the non‐eliminateable, i.e. valuations. In this article, I recall the most important concepts of knowledge developed in the twentieth‐century philosophy of science by exposing assumed axiology in, among other things: the Vienna Circle, Karl raimund Popper’s falsi cationism, the historical and social approach of (...) thomas S. Kuhn’s paradigm, and the concept of the ideals of knowledge by Stefan Amsterdamski. I argue that the axiology, and more broadly philosophy is an indelible com‐ ponent of each accepted concept of scienti c knowledge. each concept of knowledge assumes a form of its valuation. (shrink)

Gilbert Ryle’s distinction between knowledge-how and knowledge-that emerged from his criticism of the “intellectualist legend” that to do something intelligently is “to do a bit of theory and then to do a bit of practice,” and became a philosophical commonplace in the second half of the last century. In this century Jason Stanley has attacked Ryle’s distinction, arguing that “knowing-how is a species of knowing-that,” and accusing Ryle of setting up a straw man in his critique of “intellectualism.” Examining the (...) use of the terms “intellectualism” and “anti-intellectualism” in the first half of the 20th century, in a wide-ranging debate in the social sciences as well as in philosophy, I show that Ryle was not criticizing a straw man, but a live historical position. In the context of this controversy, Ryle’s position represents a third way between “intellectualism” and “anti-intellectualism,” an option that has largely gone missing in the 21st century discussion. This argument illustrates how history can inform the history of philosophy, and how the history of philosophy can inform contemporary philosophical inquiry. (shrink)

The objection of horrible commands claims that divine command metaethics is doomed to failure because it is committed to the extremely counterintuitive assumption that torture of innocents, rape, and murder would be morally obligatory if God commanded these acts. Morriston, Wielenberg, and Sinnott-Armstrong have argued that formulating this objection in terms of counterpossibles is particularly forceful because it cannot be simply evaded by insisting on God’s necessary perfect moral goodness. I show that divine command metaethics can be defended even against (...) this counterpossible version of the objection of horrible commands because we can explain the truth-value intuitions about the disputed counterpossibles as the result of conversational implicatures. Furthermore, I show that this pragmatics-based defence of divine command metaethics has several advantages over Pruss’s reductio counterargument against the counterpossible version of the objection of horrible commands. (shrink)

We examine two competing solutions to Benardete paradoxes: causal finitism, according to which nothing can have infinitely many causes, and the unsatisfiable pair diagnosis (UPD), according to which such paradoxes are logically impossible and no metaphysical thesis need be adopted to avoid them. We argue that the UPD enjoys notable theoretical advantages over causal finitism. Causal finitists, however, have levelled two main objections to the UPD. First, they urge that the UPD requires positing a ‘mysterious force’ that prevents paradoxes from (...) arising. Since such a force is implausible, the UPD is in trouble. Second, they employ recombination or patchwork principles to argue that paradoxical situations would be possible if causal finitism were false. Since such situations are not possible, causal finitism is true, and so a substantive metaphysical thesis is needed to avoid the paradoxes. We argue that the UPD proponent can successfully respond to these objections. (shrink)

Benardete paradoxes involve infinite collections of Grim Reapers, assassins, demons, deafening peals, or even sentences. These paradoxes have recently been used in arguments for finitist metaphysical theses such as temporal finitism, causal finitism, and discrete views of time. Here we develop a new finite Benardete-like paradox. We then use this paradox to defend a companions in guilt argument that challenges recent applications of patchwork principles on behalf of the aforementioned finitist arguments. Finally, we develop another problem for those applications by (...) examining the notion of exact duplication. (shrink)

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be made more complicated (...) in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

The New Evil Demon problem has been hotly debated since the case was introduced in the early 1980’s (e.g. Lehrer and Cohen 1983; Cohen 1984), and there seems to be recent increased interest in the topic. In a forthcoming collection of papers on the New Evil Demon problem (Dutant and Dorsch, forthcoming), at least two of the papers, both by prominent epistemologists, attempt to resist the problem by appealing to the distinction between justification and excuses. My primary aim here is (...) to critically evaluate this new excuse maneuver as a response to the New Evil Demon problem. -/- Their response attempts to give us reason to reject the idea that victims of the New Evil Demon have justification for believing as they do. I shall argue that this approach is ultimately unsuccessful, however much of value can be learned from these attempts. In particular, progress in the debate can be made by following those who advance the excuse maneuver and make explicit the connection between epistemic justification and epistemic norms. By doing so, the questions being debated are clarified, as is the methodology being used to attempt to answer them. (shrink)

We draw out significant consequences of a relatively popular theory of metaphysical modality—branching actualism—for cosmological arguments for God’s existence. According to branching actualism, every possible world shares an initial history with the actual world and diverges only because causal powers (or dispositions, or some such) are differentially exercised. We argue that branching actualism undergirds successful responses to two recent cosmological arguments: the Grim Reaper Kalam argument and a modal argument from contingency. We also argue that branching actualism affords a response (...) to one popular defense of the classic contingency argument. What results are new difficulties for several cosmological arguments arising from the metaphysics of modality. (shrink)

In common with traditional forms of epistemic internalism, epistemological disjunctivism attempts to incorporate an awareness condition on justification. Unlike traditional forms of internalism, however, epistemological disjunctivism rejects the so-called New Evil Genius thesis. In so far as epistemological disjunctivism rejects the New Evil Genius thesis, it is revisionary. -/- After explaining what epistemological disjunctivism is, and how it relates to traditional forms of epistemic internalism / externalism, I shall argue that the epistemological disjunctivist’s account of the intuitions underlying the New (...) Evil Genius thought experiment is at best incomplete. As presented, therefore, epistemological disjunctivism is unable to accommodate the core guiding intuitions of epistemic internalism. Given the stated aim of not being revisionary on this score, the view is at a dialectical disadvantage over the traditional forms of epistemic internalism the position is meant to replace. Unfortunately, therefore, at present, the impasse between internalism and externalism remains. (shrink)

Aristotle’s cryptic De Anima III 5 has precipitated an enormous volume of commentary, especially about the identity of what has come to be known as active intellect and how it relates to potential intellect. Some take active intellect to be the prime mover of Metaphysics Λ, others a hypostatic or cosmic principle (for example, an ideal Intellect, intellect associated with the tenth celestial sphere, etc.), and others a faculty, potentiality, or power of the human soul that is distinct in function, (...) office, or operation from potential intellect. But a very different, ontologically lightweight way of characterizing active and potential intellect can be reconstructed from fragments of a work by the only interpreter personally acquainted with Aristotle, his junior colleague, Theophrastus of Eresus. This reconstruction suggests various philosophically attractive solutions to notorious problems raised by Aristotle’s text. (shrink)

Artificial Intelligence (AI) is increasingly adopted in society, creating numerous opportunities but at the same time posing ethical challenges. Many of these are familiar, such as issues of fairness, responsibility and privacy, but are presented in a new and challenging guise due to our limited ability to steer and predict the outputs of AI systems. This chapter first introduces these ethical challenges, stressing that overviews of values are a good starting point but frequently fail to suffice due to the context (...) sensitivity of ethical challenges. Frequently, additional (ethical) values emerge for specific applications, as e.g. challenges with fraud detection are very different from those around language technologies. Second, methods to tackle these challenges are discussed. Main ethical theories (virtue ethics, consequentialism, and deontology) are shown to provide a starting point, but often lack the details needed for actionable AI Ethics. Instead, mid-level philosophical theories coupled to design-approaches such as Design for Values, together with interdisciplinary working methods, offer the best way forwards. The chapter aims to show how these approaches can lead to an ethics of AI that is actionable and that can be proactively integrated in the design of AI systems. (shrink)

In their paper Nothing but the Truth Andreas Pietz and Umberto Rivieccio present Exactly True Logic, an interesting variation upon the four-valued logic for first-degree entailment FDE that was given by Belnap and Dunn in the 1970s. Pietz & Rivieccio provide this logic with a Hilbert-style axiomatisation and write that finding a nice sequent calculus for the logic will presumably not be easy. But a sequent calculus can be given and in this paper we will show that a calculus for (...) the Belnap-Dunn logic we have defined earlier can in fact be reused for the purpose of characterising ETL, provided a small alteration is made—initial assignments of signs to the sentences of a sequent to be proved must be different from those used for characterising FDE. While Pietz & Rivieccio define ETL on the language of classical propositional logic we also study its consequence relation on an extension of this language that is functionally complete for the underlying four truth values. On this extension the calculus gets a multiple-tree character—two proof trees may be needed to establish one proof. (shrink)

In this article I argue that the value of epistemic justification cannot be adequately explained as being instrumental to truth. I intend to show that false belief, which is no means to truth, can nevertheless still be of epistemic value. This in turn will make a good prima facie case that justification is valuable for its own sake. If this is right, we will have also found reason to think that truth value monism is false: assuming that true belief does (...) have value, there is more of final epistemic value than mere true belief. (shrink)

Neo-Humean instrumentalist theories of reasons for acting have been presented with a dilemma: either they are normatively trivial and, hence, inadequate as a normative theory or they covertly commit themselves to a noninstrumentalist normative principle. The claimed result is that no purely instrumentalist theory of reasons for acting can be normatively adequate. This dilemma dissolves when we understand what question neo-Humean instrumentalists are addressing. The dilemma presupposes that neo-Humeans are attempting to address the question of how to act, 'simpliciter'. Instead, (...) they are evaluating actions from the agent's normative perspective. (shrink)

We discuss at some length evidence from the cognitive science suggesting that the representations of objects based on spatiotemporal information and featural information retrieved bottomup from a visual scene precede representations of objects that include conceptual information. We argue that a distinction can be drawn between representations with conceptual and nonconceptual content. The distinction is based on perceptual mechanisms that retrieve information in conceptually unmediated ways. The representational contents of the states induced by these mechanisms that are available to a (...) type of awareness called phenomenal awareness constitute the phenomenal content of experience. The phenomenal content of perception contains the existence of objects as separate things that persist in time and time, spatiotemporal information, and information regarding relative spatial relations, motion, surface properties, shape, size, orientation, color, and their functional properties. (shrink)

One of the attractions of the Humean instrumentalist theory of practical rationality is that it appears to offer a special connection between an agent's reasons and her motivation. The assumption that Humeanism is able to assert a strong connection between reason and motivation has been challenged, most notably by Christine Korsgaard. She argues that Humeanism is not special in the connection it allows to motivation. On the contrary, Humean theories of practical rationality do connect reasons and motivation in a unique (...) and attractive way, though the nature of this connection has sometimes been misunderstood by both defenders and detractors of the theory. (shrink)

Many believe that the rational evaluation of actions depends on the rational evaluation of even basic desires. Hume, though, viewed desires as "original existences" which cannot be contrary to either truth or reason. Contemporary critics of Hume, including Norman, Brandt and Parfit, have sought a basis for the rational evaluation of desires that would deny some basic desires reason-giving force. I side with Hume against these modern critics. Hume's concept of rational evaluation is admittedly too narrow; even basic desires are, (...) despite their nonrepresentational nature, subject to rational evaluation. But this evaluation is not relevant to their tendency to generate reasons for action, and does not undermine the spirit of the Humean view of rational action. (shrink)

These essays draw on work in the history and philosophy of science, the philosophy of mind and language, the development of concepts in children, conceptual..

In this introduction, before summarizing the contents of the volume, the authors characterize materialism as it is understood within the philosophy of mind, and they identify three respects in which materialism is on the wane.

Skipper and Millstein analyze natural selection and mechanism, concluding that natural selection is not a mechanism in the sense of the new mechanistic philosophy. Barros disagrees and provides his own account of natural selection as a mechanism. This discussion identifies a missing piece of Barros's account, attempts to fill in that piece, and reconsiders the revised account. Two principal objections are developed: one, the account does not characterize natural selection; two, the account is not mechanistic. Extensive and persistent variability causes (...) both of these difficulties, so further attempts to describe natural selection as a mechanism are also unlikely to succeed. (shrink)

In the first section, I characterize skeptical theism more fully. This is necessary in order to address some important misconceptions and mischaracterizations that appear in the essays by Maitzen, Wilks, and O’Connor. In the second section, I describe the most important objections they raise and group them into four “families” so as to facilitate an orderly series of responses. In the four sections that follow, I respond to the objections.

In general, epistemic internalists hold that an individual’s justification for a belief is exhausted by her reflectively accessible reasons for thinking that the contents of her beliefs are true. Applying this to the epistemology of testimony, a hearer’s justification for beliefs acquired through testimony is exhausted by her reflectively accessible reasons to think that the contents of the speaker’s testimony is true. A consequence of internalism is that subjects that are alike with respect to their reflectively accessible reasons are alike (...) with respect to what they have justification to believe. Testimony should be thought no different: hearers that are alike with respect to reflectively accessible reasons to think that a speaker’s testimony is true are alike with respect to their justification for beliefs based upon that testimony. But it has been recently argued that this view faces powerful counterexamples. So the central question is this: assuming that a hearer can acquire justification to believe a proposition through the testimony of a speaker, can epistemic internalism provide the resources to explain how such justification is possible? My aim in this paper is to address these counterexamples, and in so doing, defend epistemic internalist accounts of testimony. (shrink)

This chapter first surveys general issues in the epistemic internalism / externalism debate: what is the distinction, what motivates it, and what arguments can be given on both sides. -/- The second part of the chapter will examine the internalism / externalism debate as regards to the specific case of the epistemology of memory belief.

This article argues that a person’s well-being at a time and the goodness of her life are two distinct values. It is commonly accepted as platitudinous that well-being is what makes a life good for the person who lives it. Even philosophers who distinguish between well-being at a time and the goodness of a life still typically assume that increasing a person’s well-being at some particular moment, all else equal, necessarily improves her life on the whole. I develop a precise (...) statement of this standard assumption, and then show that it is subject to counterexamples. The possibility of such counterexamples depends only on premises similar to those sometimes invoked to argue that a person’s well-being over a long period is not simply the aggregate well-being of the shorter periods that compose the long period. The refutation of the standard assumption linking well-being and life-goodness entails that these are distinct and sometimes divergent values. As an alternative to the standard assumption, it is proposed that well-being is best understood as an ingredient in a good life. (shrink)

In the exceptional book _Divine Holiness and Divine Action_, Mark Murphy defends what he calls the _holiness framework _for divine action. The purpose of our essay-response to Murphy’s book is to consider an alternative framework for divine action, what we call the _agapist framework_. We argue that the latter framework is more probable than Murphy’s holiness framework with respect to_ select _theological desiderata.

Epistemic internalism, by stressing the indispensability of the subject’s perspective, strikes many as plausible at first blush. However, many people have tended to reject the position because certain kinds of beliefs have been thought to pose special problems for epistemic internalism. For example, internalists tend to hold that so long as a justifier is available to the subject either immediately or upon introspection, it can serve to justify beliefs. Many have thought it obvious that no such view can be correct, (...) as it has been alleged that internalism cannot account for the possibility of the justification of beliefs stored in memory. -/- My aim in this paper is to offer a response that explains how memory justification is possible in a way that is consistent with epistemic internalism and an awareness condition on justification. Specifically, I will explore the plausibility of various options open to internalists, including both foundationalist and non-foundationalist approaches to the structure of justification. I intend to show that despite other difficult challenges that epistemic internalism might face, memory belief poses no special problems that the resources of internalism cannot adequately address. (shrink)

How ought you to evaluate your options if you're uncertain about what's fundamentally valuable? A prominent response is Expected Value Maximisation (EVM)—the view that under axiological uncertainty, an option is better than another if and only if it has the greater expected value across axiologies. But the expected value of an option depends on quantitative probability and value facts, and in particular on value comparisons across axiologies. We need to explain what it is for such facts to hold. Also, EVM (...) is by no means self-evident. We need an argument to defend that it’s true. This book introduces an axiomatic approach to answer these worries. It provides an explication of what EVM means by use of representation theorems: intertheoretic comparisons can be understood in terms of facts about which options are better than which, and mutatis mutandis for intratheoretic comparisons and axiological probabilities. And it provides a systematic argument to the effect that EVM is true: the theory can be vindicated through simple axioms. The result is a formally cogent and philosophically compelling extension of standard decision theory, and original take on the problem of axiological or normative uncertainty. (shrink)

Classically, gratitude is a tri-polar construal, logically ordering a benefactor, a benefice, and a beneficiary in a favour-giving-receiving situation. Grammatically, the poles are distinguished and bound together by the prepositions ”to’ and ”for’; so I call this classic concept ”to-for’ gratitude. Classic religious gratitude follows this schema, with God as the benefactor. Such gratitude, when felt, is a religious experience, and a reliable readiness or ”habit’ of such construal is a religious virtue. However, atheists have sometimes felt an urge or (...) need for an analogous experience and virtue of gratitude, and theists sometimes feel intellectual discomfort with classical theistic gratitude on consideration of the misfortunes that characterize our life along with its blessings. In response, another conception of religious gratitude has been attempted, a construal that lacks the to-for structure. This paper probes the significance of the benefactor for gratitude, both secular and religious, and, with Søren Kierkegaard’s help, some features of the theology of classical religious gratitude that dissolve the problem of misfortunes. (shrink)

In this article, we explore the implications of opposing domains theory for developing ethical leaders. Opposing domains theory highlights a neurological tension between analytic reasoning and socioemotional reasoning. Specifically, when we engage in analytic reasoning, we suppress our ability to engage in socioemotional reasoning and vice versa. In this article, we bring together the domains of neuroscience, psychology, and ethics, to inform our theorizing around ethical leadership. We propose that a key issue for ethical leadership is achieving a healthy balance (...) between analytic reasoning and socioemotional reasoning. We argue that organizational culture often encourages too heavy a reliance on nonemotional forms of reasoning to arrive at moral judgments. As a result, leaders run the risk of suppressing their ability to pay attention to the human side of moral dilemmas and, in doing so, dehumanize colleagues, particularly subordinates, and clients. (shrink)

According to the standard account of forgiveness, you forgive your wrongdoer by overcoming your resentment towards them. But how exactly must you do so? And when is such overcoming fitting? The aim of this paper is to introduce a novel version of the standard account to answer these questions. Its core idea is that the reactive attitudes are a fitting response not just to someone’s blameworthiness, but to their blameworthiness being significant for you, or worthy of your caring, in virtue (...) of your relationship to it. Someone’s blameworthiness is significant for you to the extent you’re bound up with what grounds it––e.g. with the wrongdoer’s being a participant in human relationships, with their attitudes, or with the victim’s being a source of demands. So you may fittingly not care about someone’s blameworthiness if it’s sufficiently insignificant for you in this manner––e.g. if their wrong happened far off in place and time. And forgiveness revolves around this. You forgive your wrongdoer if and only if, partly out of goodwill towards them, you cease to care about their blameworthiness––a bit as if their wrong had happened far off. If I’m right, this agent-relativity-based account can resolve the apparent ‘paradoxy of forgiveness’, satisfies a number of desiderata, and is plausible on an intuitive level. (shrink)

In their recent paper Bi-facial truth: a case for generalized truth values Zaitsev and Shramko [7] distinguish between an ontological and an epistemic interpretation of classical truth values. By taking the Cartesian product of the two disjoint sets of values thus obtained, they arrive at four generalized truth values and consider two “semi-classical negations” on them. The resulting semantics is used to define three novel logics which are closely related to Belnap’s well-known four valued logic. A syntactic characterization of these (...) logics is left for further work. In this paper, based on our previous work on a functionally complete extension of Belnap’s logic, we present a sound and complete tableau calculus for these logics. It crucially exploits the Cartesian nature of the four values, which is reflected in the fact that each proof consists of two tableaux. The bi-facial notion of truth of Z&S is thus augmented with a bi-facial notion of proof. We also provide translations between the logics for semi-classical negation and classical logic and show that an argument is valid in a logic for semi-classical negation just in case its translation is valid in classical logic. (shrink)

A common view among nontheists combines the de jure objection that theism is epistemically unacceptable with agnosticism about the de facto objection that theism is false. Following Plantinga, we can call this a “proper” de jure objection—a de jure objection that does not depend on any de facto objection. In his Warranted Christian Belief, Plantinga has produced a general argument against all proper de jure objections. Here I first show that this argument is logically fallacious (it makes subtle probabilistic fallacies (...) disguised by scope ambiguities), and proceed to lay the groundwork for the construction of actual proper de jure objections. (shrink)

Certain advocates of the so-called “neo-logicist” movement in the philosophy of mathematics identify themselves as “neo-Fregeans” (e.g., Hale and Wright), presenting an updated and revised version of Frege’s form of logicism. Russell’s form of logicism is scarcely discussed in this literature and, when it is, often dismissed as not really logicism at all (in light of its assumption of axioms of infinity, reducibility and so on). In this paper I have three aims: firstly, to identify more clearly the primary meta-ontological (...) and methodological differences between Russell’s logicism and the more recent forms; secondly, to argue that Russell’s form of logicism offers more elegant and satisfactory solutions to a variety of problems that continue to plague the neo-logicist movement (the bad company objection, the embarrassment of richness objection, worries about a bloated ontology, etc.); thirdly, to argue that neo-Russellian forms of logicism remain viable positions for current philosophers of mathematics. (shrink)

Classical Sparta is an enigma in many ways, but for ancient and contemporary political theorists it is especially intriguing insofar as its politeia (or its educational/political/social system or “constitution”) produced a city-state that was both the hegemon of all other Greek city-states, for instance during the 5th century Persians wars, but was also ignobly defeated by Thebes at the battle of Leuctra in 371, slightly more than a century later, after which its hegemony collapsed and its subject population of helots (...) won a war of emancipation. How did Sparta field citizen-soldiers in the 5th century who were without parallel in their bravery and military prowess? And why did Sparta, perhaps under the same politeia, collapse just over a century later? Xenophon, Plato, Aristotle, and Plutarch searched for answers to such questions in the Spartan public educational program, its mixed constitutions, and its apparently militaristic goal and orientation. Such 4th century intellectuals (and Plutarch, writing in the 1st century CE) debated whether Sparta’s collapse was the result of deep-rooted problems within its Lycurgan constitution or in Sparta’s subsequent departure from that constitution; there also is significant debate concerning the education and roles of women within Spartan society. (shrink)

Many assume that whenever government is entitled to make a law, it is entitled to enforce that law coercively. I argue that the justification of legal authority and the justification of governmental coercion come apart. Both in ideal theory and in actual human societies, governments are sometimes entitled to make laws that they are not entitled to enforce coercively.

In the present article, he explains why divine silence poses a serious intellectual obstacle to belief in God, and then goes on to consider ways of overcoming that obstacle. After considering several ways in which divine silence might actually be beneficial to human beings, he argues that perhaps silence is nothing more or less than God’s preferred mode of interaction with creatures like us. Perhaps God simply desires communion rather than overt communication with human beings, and perhaps God has provided (...) ways for us to experience God’s presence richly even amidst the silence. (shrink)

My goal in this paper is to show that naturalists cannot reasonably endorse moral realism. My argument will come in two parts. The first part aims to show that any plausible and naturalistically acceptable argument in favor of belief in objective moral properties will appeal in part to simplicity considerations (broadly construed)—and this regardless of whether moral properties are reducible to non-moral properties. The second part argues for the conclusion that appeals to simplicity justify belief in moral properties only if (...) either those properties are not objective or something like theism is true. Thus, if my argument is sound, naturalists can reasonably accept moral realism only if they are prepared to accept something like theism. But, as will become clear, naturalists can reasonably accept theism or something like it only if belief in some such doctrine is justified by the methods of science. For present purposes, I’ll assume (what I think virtually every naturalist will grant) that belief in theism and relevantly similar doctrines is not justified by the methods of science. Thus, I will conclude that naturalists cannot reasonably accept moral realism. (shrink)

Many biologists and philosophers have worried that importing models of reasoning from the physical sciences obscures our understanding of reasoning in the life sciences. In this paper we discuss one example that partially validates this concern: part-whole reductive explanations. Biology and physics tend to incorporate different models of temporality in part-whole reductive explanations. This results from differential emphases on compositional and causal facets of reductive explanations, which have not been distinguished reliably in prior philosophical analyses. Keeping these two facets distinct (...) facilitates the identifi cation of two further aspects of reductive explanation: intrinsicality and fundamentality. Our account provides resources for discriminating between different types of reductive explanation and suggests a new approach to comprehending similarities and differences in the explanatory reasoning found in biology and physics. (shrink)

ABSTRACT Self-Interest and Public Interest in Western Politics showed that the public, politicians, and bureaucrats are often public spirited. But this does not invalidate public-choice theory. Public-choice theory is an ideal type, not a claim that self-interest explains all political behavior. Instead, public-choice theory is useful in creating rules and institutions that guard against the worst case, which would be universal self-interestedness in politics. In contrast, the public-interest hypothesis is neither a comprehensive explanation of political behavior nor a sound basis (...) for institutional design. (shrink)