This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1.Providing information about research integrity § 2.Providing education, training and mentoring § 3.Strengthening a research integrity culture § 4.Facilitating open dialogue § 5.Wise incentive management § 6.Implementing quality assurance procedures § 7.Improving the work environment and work satisfaction § 8.Increasing transparency of misconduct cases § 9.Opening up research § 10.Implementing safe and effective whistle-blowing channels § 11.Protecting the alleged perpetrators § 12.Establishing a research integrity committee and appointing an ombudsperson § 13.Making explicit the applicable standards for research integrity. (shrink)

Buchanan and Powell hope to rescue optimism about moral perfectibility from the ’received view’ of human evolution, by tweaking our view of the innate character of morality. I argue that their intervention is hampered by an unnecessary commitment to nativism, by gender bias within the received view, and by liberal presuppositions.

The problem of plant individuality is something which has vexed botanists throughout the ages, with fashion swinging back and forth from treating plants as communities of individuals (Darwin 1800 ; Braun and Stone 1853 ; Münch 1938 ) to treating them as organisms in their own right, and although the latter view has dominated mainstream thought most recently (Harper 1977 ; Cook 1985 ; Ariew and Lewontin 2004 ), a lively debate conducted mostly in Scandinavian journals proves that the issues (...) are far from being resolved (Tuomi and Vuorisalo 1989b ; Fagerström 1992 ; Pan and Price 2001 ). In this paper I settle the matter once and for all, by showing which elements of each side are correct. (shrink)

Biological theory demands a clear organism concept, but at present biologists cannot agree on one. They know that counting particular units, and not counting others, allows them to generate explanatory and predictive descriptions of evolutionary processes. Yet they lack a unified theory telling them which units to count. In this paper, I offer a novel account of biological individuality, which reconciles conflicting definitions of ‘organism’ by interpreting them as describing alternative realisers of a common functional role, and then defines individual (...) organisms as essentially possessing some mechanisms that play this role. (shrink)

The prominent philosopher Bernard Williams (1985) opened his Ethics and the Limits of Philosophy with: “It is not a trivial question, Socrates said: what we are talking about is how one should live” (p. 1) and asked whether Socrates’ question is the proper starting point for moral philosophy. In this paper, I will explore an effect of a very specific life event: a “cliff-edge” retirement. I will look at the concept of ground projects and show how cliff-edge retirements create ill-shaped (...) projects reflecting the loss of important workplace benefits such as purposeful work and social collaborations. This type of retirement prematurely closes the ground project before its natural conclusion. I will argue that attempts to recover it will likely prove difficult, inauthentic and will not remedy the project’s wrongful shape. (shrink)

This chapter develops the idea that the germ-soma split and the suppression of individual fitness differences within the corporate entity are not always essential steps in the evolution of corporate individuals. It illustrates some consequences for multilevel selection theory. It presents evidence that genetic heterogeneity may not always be a barrier to successful functioning as a higher-level individual. This chapter shows that levels-of-selection theorists are wrong to assume that the central problem in transitions is always that of minimizing within-group competition. (...) Evidence of intralevel conflict does not qualify as evidence against the existence of a higher level of selection. (shrink)

I argue for the usefulness of the evolutionary kind of biological individual.

It will be shown in this article that an ontological approach for some problems related to the interpretation of Quantum Mechanics (QM) could emerge from a re-evaluation of the main paradox of early Greek thought: the paradox of Being and non-Being, and the solutions presented to it by Plato and Aristotle. More well known are the derivative paradoxes of Zeno: the paradox of motion and the paradox of the One and the Many. They stem from what was perceived by classical (...) philosophy to be the fundamental enigma for thinking about the world: the seemingly contradictory results that followed from the co-incidence of being and non-being in the world of change and motion as we experience it, and the experience of absolute existence here and now. The most clear expression of both stances can be found, again following classical thought, in the thinking of Heraclitus of Ephesus and Parmenides of Elea. The problem put forward by these paradoxes reduces for both Plato and Aristotle to the possibility of the existence of stable objects as a necessary condition for knowledge. Hence the primarily ontological nature of the solutions they proposed: Plato’s Theory of Forms and Aristotle’s metaphysics and logic. Plato’s and Aristotle’s systems are argued here to do on the ontological level essentially the same: to introduce stability in the world by introducing the notion of a separable, stable object, for which a ‘principle of contradiction’ is valid: an object cannot be and not-be at the same place at the same time. So it becomes possible to forbid contradiction on an epistemological level, and thus to guarantee the certainty of knowledge that seemed to be threatened before. After leaving Aristotelian metaphysics, early modern science had to cope with these problems: it did so by introducing “space” as the seat of stability, and “time” as the theater of motion. But the ontological structure present in this solution remained the same. Therefore the fundamental notion ‘separable system’, related to the notions observation and measurement, themselves related to the modern concepts of space and time, appears to be intrinsically problematic, because it is inextricably connected to classical logic on the ontological level. We see therefore the problems dealt with by quantum logic not as merely formal, and the problem of ‘non-locality’ as related to it, indicating the need to re-think the notions system, entity, as well as the implications of the operation ‘measurement’, which is seen here as an application of classical logic (including its ontological consequences) on the material world. (shrink)

Because we tend to study fight books in isolation, we often forget how difficult it is to understand the precise place they occupy in the sociocultural and historical fabric of their time, and spill the many clues they inevitably contain on their owner, their local society, their precise purpose. In order to unlock that information, we need to study them in their broader sociocultural and historical context. This requires a background and research skills that are not always easily accessible to (...) everyone. To illustrate the point, in this paper I show in some detail what is required to make sense of the claim that Aristotelian philosophy and science influenced the medieval fight books in relevant ways, and that understanding this influence helps us to better understand the fight books per se. I give an outline of the general historical framework, and apply it to a testcase: Talhoffer’s Thott 290 2° Ms., with some interesting results. My hope is that this framework may be of some use to other researchers in HEMA Studies who want to dig deeper in sources of interest to them. (shrink)

We investigate the structure common to causal theories that attempt to explain a (part of) the world. Causality implies conservation of identity, itself a far from simple notion. It imposes strong demands on the universalizing power of the theories concerned. These demands are often met by the introduction of a metalevel which encompasses the notions of 'system' and 'lawful behaviour'. In classical mechanics, the division between universal and particular leaves its traces in the separate treatment of cinematics and dynamics. This (...) analysis is applied to the mechanical theories of Newton and Leibniz, with some surprising results. (shrink)

We defend a noetic account of intramathematical explanation. On this view, a piece of mathematics is explanatory just in case it produces understanding of an appropriate type. We motivate the view by presenting some appealing features of noeticism. We then discuss and criticize the most prominent extant version of noeticism, due to Inglis and Mejía Ramos, which identifies explanatory understanding with the possession of well-organized cognitive schemas. Finally, we present a novel noetic account. On our view, explanatory understanding arises from (...) meeting specific explanatory objectives. We defend a cluster-concept account of explanatory objectives and identify four important subfamilies within the relevant network of resemblance relations. The resulting view is objectivist (in the sense that it takes explanatory success to be a matter of observer-independent fact), broader in scope than why-question-based accounts, compatible with empirical findings on experts’ explanatory judgments, and capable of generalizing (with appropriate provisos) to scientific explanation as a whole. It thus fulfills Friedman’s half-century-old demand for a general and objectivist theory which accounts for the link between explanation and understanding. (shrink)

In this paper, we give a flavour of how, against the odds, Reggio-Emilia-inspired pedagogical documentation can work in reconceptualizing environmental education, reconfiguring child subjectivity and provoking an ontological shift from autopoiesis to sympoiesis in teacher education. Working posthuman(e)ly and transdisciplinarily across three foundation phase teacher education courses at a university in South Africa, we situate our teaching within current environmental precarities. We show how we stirred up trouble in and outside our university classroom and provoked our students to “make kin” (...) with children, each other, other animals, and the more-than-human, but also to stay with the trouble, that is, to learn to be truly present in colonized spaces. (shrink)

In de hiernavolgende bijdrage zal het erom gaan te pogen een ander licht te werpen op de globalisering der wereldeconomie die onze planeet sinds enkele decennia teistert. In de theoretische aandacht die deze historische ontwikkeling te beurt viel gedurende de tweede helft van de voorbije eeuw, werd het verband met zowel de ‘economisering’ als de ‘technologisering’ van onze leefwereld zoals geduid in de marxistische en techniekphilosophische critiek centraal gesteld; zij werd tevens gesitueerd in de context van “de postmoderne conditie” in (...) den zin van Lyotard2. Ook de rationaliteitscrisis tout court die hiermee samenhangt beschouw ik als een uitgangspunt, hoewel men over haar aard en oorzaken van mening kan verschillen. De oorspronkelijkheid van deze bijdrage zal dan ook niet te vinden zijn in de bespreking van een der bovenvermelde punten, maar in een ander begrip van de betrekkingen tussen de totaliteit van dit proces en de in onze gewaarwordingen gegeven, ‘natuurlijke’ werkelijkheid. (shrink)

Our concern in the following pages will be the ontology of the relation between living beings (especially, but not exclusively, humans) and the technological artefacts of our late-industrial society. The theme is not new, but important in the context of the emergence and globalisation of so called “post- modern” society. The eventual originality of the present contribution is to be situated in its interpretative framework, i.e., a specific conception of reality's deep ontology, overlooked in general exactly because of the “technological” (...) structure impressed since centuries upon our ways of perceiving of and reasoning about the world. I refer to this neglected but fundamental characteristic of reality as its ontological paradoxicality. (shrink)

The article summarises in an accessible way the (lack of) debate in France between different economic schools — the hegemonic neoclassical school with its positivist pretenses versus more historical schools of a Marxist or Keynesian orientation.

Book review: Emmanuel Todd, "Où en sommes-nous? Une esquisse de l'histoire humaine" (Seuil, 2017).

In their recent work, L. Graham and J.-M. Kantor discuss a remarkable connection between diverging conceptions of the mathematical infinite in Russia and France at the beginning of the twentieth century and the religious convictions of their respective authors. They expand much more on the Russian side of the cultural equation they propose; I do believe, however, that the French (or rather ‘West European’) side is more complex than it seems, and that digging deeper into it is worthwhile. In this (...) paper I shall therefore broaden the path laid out in Graham and Kantor’s work, by connecting two different strands of research concerning the origin of what I loosely call ‘formal’ ideas: firstly, the rich but complex relation between logic and rhetoric throughout European cultural history, and secondly, the impact of religious convictions on the formation of certain mathematical and scientific ideas during Renaissance and Early Modernity, especially but not exclusively in France. (shrink)

Isaac Newton, in popular imagination the Ur-scientist, was an outstanding humanist scholar. His researches on, among others, ancient philosophy, are thorough and appear to be connected to and fit within his larger philosophical and theological agenda. It is therefore relevant to take a closer look at Newton’s intellectual choices, at how and why precisely he would occupy himself with specific text-sources, and how this interest fits into the larger picture of his scientific and intellectual endeavours. In what follows, we shall (...) follow Newton into his study and look over his shoulder while reading compendia and original source-texts in his personal library at Cambridge, meticulously investigating and comparing fragments and commentaries, and carefully keeping track in private notes of how they support his own developing ideas. Indeed, Newton was convinced that precursors to his own insights and discoveries were present already in Antiquity, even before the Greeks, in ancient Egypt, and he puts a lot of time and effort into making the point, especially, and not incidentially, in the period between the first and the second edition of the Principia. A clear understanding of his reading of the classic sources therefore matters to our understanding of its content and gestation process. In what follows we will confine ourselves to the classical legacy, and investigate Newton’s intellectual intercourse with it. (shrink)

"Thinking about thinking", the topic of this section of our volume, leads us into an Escherian web of self-referential interconnections — which nevertheless make sense, at least if we do not shy away at once in the face of paradox, for fear of inconsistency. How do our critical faculties enter the picture? Adding a few conceptual dimensions to the merely linearly causal one may help us to shed light on the issue, and may help us also to understand some of (...) the basic strategies "Western" thought has developed throughout its historical pathway in its conscious dealings with the 'real'. Of course, in a few pages it is impossible to do justice to this complicated subject. But I'll try to give the reader an as clear as possible description of the, in my view, crucial issues, pointing out the ways they resonate into the many fields of interest represented in the intended readership, and leave it to the reader to dig deeper through the given references. (shrink)

In this essay I propose a new measure of social welfare. It captures the intuitive idea that quantity, quality, and equality of individual welfare all matter for social welfare. More precisely, it satisfies six conditions: Equivalence, Dominance, Quality, Strict Monotonicity, Equality and Asymmetry. These state that i) populations equivalent in individual welfare are equal in social welfare; ii) a population that dominates another in individual welfare is better; iii) a population that has a higher average welfare than another population is (...) better, other things being equal; iv) the addition of a well-faring individual makes a population better, whereas the addition of an ill-faring individual makes a population worse; v) a population that has a higher degree of equality than another population is better, other things being equal; and vi) individual illfare matters more for social welfare than individual welfare. By satisfying the six conditions, the measure improves on previously proposed measures, such as the utilitarian Total and Average measures, as well as different kinds of Prioritarian measures. (shrink)

A concise introduction (in Dutch) to the work of Giorgio Agamben, from the perspective of the central question in his philosophy under what conditions community or society today are possible, not based on in the end always artbitrary principles of exclusion — be they historical, biological, ...

Background: Exposomics, the study of the exposome, is flourishing, but the field is not well defined. The term “exposome” refers to all environmental influences and associated biological responses throughout the lifespan. However, this definition is very similar to that of the term “environment”—the external elements and conditions that surround and affect the life and development of an organism. Consequently, the exposome seems to be nothing more than a synonym for the environment, and exposomics a synonym for environmental research. As a (...) result, some have rebranded their “standard” environmental health research with the neologistic exposome term, whereas others ignore or seek to abandon the seemingly redundant concept of the exposome. -/- Objectives: We argue that exposomics needs to sharpen its mission focus to counteract this apparent redundancy. Exposomics should be defined as a research program in environmental health aimed at enabling a comprehensive and discovery-driven approach to identifying environmental determinants of human health. Similar to the aim of the Human Genome Project, exposomics aims to analyze the complete complexity of exposures and their corresponding biological responses. Exposomics’ primary premise is that the existence of undiscovered, potentially interconnected, nongenetic (environmental) risk factors for health necessitates a comprehensive discovery-driven analysis approach. -/- Discussion: We argue that exposomics researchers should adopt our reconceptualization of exposomics and focus on the productiveness and integrity of their research program: its purpose and principles. We suggest that exposomics researchers should coordinate the writing of reviews that assess the program’s productiveness and integrity, as well as provide a platform for exposomics researchers to define their vision for the field. (shrink)

Scholarly debates on the Critique of Pure Reason have largely been shaped by epistemological questions. Challenging this prevailing trend, Kant's Reform of Metaphysics is the first book-length study to interpret Kant's Critique in view of his efforts to turn Christian Wolff's highly influential metaphysics into a science. Karin de Boer situates Kant's pivotal work in the context of eighteenth-century German philosophy, traces the development of Kant's conception of critique, and offers fresh and in-depth analyses of key parts of the Critique (...) of Pure Reason, including the Transcendental Deduction, the Schematism Chapter, the Appendix to the Transcendental Analytic, and the Architectonic. The book not only brings out the coherence of Kant's project, but also reconstructs the outline of the 'system of pure reason' for which the Critique was to pave the way, but that never saw the light. (shrink)

The concept of adaptation is pivotal to modern evolutionary thinking, but it has long been the subject of controversy, especially in respect of the relative roles of selection versus constraints in explaining the traits of organisms. This paper tackles a different problem for the concept of adaptation: its interpretation in light of multilevel selection theory. In particular, I arbitrate a dispute that has broken out between the proponents of rival perspectives on multilevel adaptations. Many experts now say that multilevel and (...) kin selection views are mathematically equivalent to one another—that the mathematical accounting of evolution can be carried out at any hierarchical level one chooses. But what does this formal equivalence imply - are they equivalent in other ways too? I show here that significant conceptual non-equivalence has survived: the two sides commit to different views regarding how much selection has to act at a level before we can call traits at that level adaptations; about whether policing mechanisms are adaptations, and about whether non-organisms can bear adaptations. (shrink)

Since the dawn of philosophy, the paradoxical interconnection between the continuous and the discrete plays a central rôle in attempts to understand the ontology of the world, while defying all attempts at consistent formulation. I investigate the relation between (classical) logic and concepts of “space” and “time” in physical and metaphysical theories, starting with the Greeks. An important part of my research consists in exploring the strong connections between paradoxes as they appear and are dealt with in ancient philosophy, and (...) their re-appearance in early modern natural philosophy, as well as in the foundations of contemporary science and mathematics. The way paradoxes are dealt with sheds light on a theory’s hidden metaphysical assumptions, especially with respect to matter, space, time and causation, it defines its ontological signature. This conclusion led me to the in-depth study of early modern natural philosophy, the origin of natural science, especially the influences ancient thinkers had on the new conceptions of space, time and causation developed by Newton, Huygens and Leibniz. (shrink)

In the Critique of Pure Reason and elsewhere, Kant uses the term ‘object’ in various ways and often without clearly signaling its different meanings. As a result, it is hard to gauge the extent to which Kant’s account of the object of cognition breaks new ground. In this article, I take the Critique to establish what is required to generate an object of cognition per se soleley by examining the various ways in which the human mind can objectify the content (...) of its representations. To clarify this endeavor, I distinguish four different ways in which the term ‘object’ is used in the Critique, namely, to refer to (1) material things, (2) the content of any type of thought, (3) the mind-immanent correlate of a cognition in the broad sense of the term, and (4) the mind-immanent correlate of a cognition in the strict sense of the term. On my reading, the fourth meaning of the term ‘object’ is key to the Transcendental Deduction and completes Kant’s unprecedented conception of the cognitive acts by means of which the human mind produces objects of cognition out of a manifold of representations. (shrink)

The amount of realist positions put forward by philosophers of religion and theologians is impressive. one can certainly doubt whether there is a need for yet another alternative. However, most realist positions employed in studies on religion fall prey to Hilary Putnam’s criticism against metaphysical realism. This gives rise to a dilemma that I aim at solving by introducing yet another realist position, namely non-metaphysical realism.

This article challenges the prevailing interpretations of Hegel's account of the concept "contradiction" in the Science of Logic by arguing that it is concerned with the principle of Hegel's method rather than with the classical law of non-contradiction. I first consider Hegel's Doctrine of Essence in view of Kant's discussion of the concepts of reflection in the first Critique. On this basis, I examine Hegel's account of the logical principles based on the concepts "identity," "opposition," and "contradiction." Finally, I point (...) out how the principle Hegel derives from the concept of contradiction actually informs his own method. (shrink)

In recent years, exposome research has been put forward as the next frontier for the study of human health and disease. Exposome research entails the analysis of the totality of environmental exposures and their corresponding biological responses within the human body. Increasingly, this is operationalized by big-data approaches to map the effects of internal as well as external exposures using smart sensors and multiomics technologies. However, the ethical implications of exposome research are still only rarely discussed in the literature. Therefore, (...) we conducted a systematic review of the academic literature regarding both the exposome and underlying research fields and approaches, to map the ethical aspects that are relevant to exposome research. We identify five ethical themes that are prominent in ethics discussions: the goals of exposome research, its standards, its tools, how it relates to study participants, and the consequences of its products. Furthermore, we provide a number of general principles for how future ethics research can best make use of our comprehensive overview of the ethical aspects of exposome research. Lastly, we highlight three aspects of exposome research that are most in need of ethical reflection: the actionability of its findings, the epidemiological or clinical norms applicable to exposome research, and the meaning and action–implications of bias. (shrink)

Hypocrisy is a multi-faceted concept that has been studied empirically by psychologists and discussed logically by philosophers. In this study, we pose various behavioral scenarios to research participants and ask them to indicate whether the actor in the scenario behaved hypocritically. We assess many of the components that have been considered to be necessary for hypocrisy (e.g., the intent to deceive, self-deception), factors that may or may not be distinguished from hypocrisy (e.g., weakness of will), and factors that may moderate (...) hypocrisy (e.g., the degree of discrepancy between the attitude and behavior, whether the attitude is stated publicly, and the nature and severity of the behavioral consequences). Our findings indicate that lay conceptions of hypocrisy are often at odds with philosophical speculation. We argue that a complete understanding of the criteria for hypocrisy requires consideration of how ordinary people construe the concept. In contrast to some concepts (e.g., physical causation), for which lay conceptions, while interesting, are largely irrelevant, hypocrisy is an essential component of social judgment. One could argue, therefore, that folk wisdom is the ultimate arbiter of what hypocrisy entails. We note limitations of our methodology and suggest avenues for future research. (shrink)

This chapter examines Hegel’s conception of philosophical critique in order to shed light on the force and limits of the method that has become known as immanent critique. At least in modern philosophy, it was Kant who first conceived of critique as a form of reflection that draws its criterion from reason itself. As I argue, Hegel is deeply indebted to Kant in this respect. The chapter begins with an analysis of Hegel's seminal essay ‘On the Essence of Philosophical Criticism (...) Generally, and its Relationship to the Present State of Philosophy in Particular’, published in 1802. After a brief discussion of the Phenomenology, I turn to his Philosophy of Right. These texts make clear, I argue, that the criterion from which immanent critique takes its bearings is necessarily tainted with a particularity that it cannot affirm without losing its force. According to this account, immanent critique comes to refer to a form of reflection that is more complicated and more precarious than Kant and Hegel seem to have assumed. (shrink)

The present paper aims to trace back Kant’s account of the schematism of the pure understanding in the Critique of Pure Reason to the Dissertation. I do so by discussing Kant’s understanding of sensible cognition in view of his assessment of metaphysics. I argue, first, that Kant in both texts aims to defend metaphysics against skeptical attacks by discarding those of its elements he considers unwarranted and, second, that this undertaking hinges on his account of concepts that function as the (...) sensible condition of cognition. Yet whereas Kant argues in 1770 that metaphysics must be purely intellectual, he in 1781 draws on his earlier account of sensible concepts to argue, against the Wolffians, that determining intelligible objects by purely intellectual means does not amount to cognition proper. (shrink)

Virtues, broadly understood as stable and robust dispositions for certain responses across morally relevant situations, have been a growing topic of interest in psychology. A central topic of discussion has been whether studies showing that situations can strongly influence our responses provide evidence against the existence of virtues (as a kind of stable and robust disposition). In this review, we examine reasons for thinking that the prevailing methods for examining situational influences are limited in their ability to test dispositional stability (...) and robustness; or, then, whether virtues exist. We make the case that these limitations can be addressed by aggregating repeated, cross-situational assessments of environmental, psychological and physiological variables within everyday life—a form of assessment often called ecological momentary assessment (EMA, or experience sampling). We, then, examine how advances in smartphone application (app) technology, and their mass adoption, make these mobile devices an unprecedented vehicle for EMA and, thus, the psychological study of virtue. We, additionally, examine how smartphones might be used for virtue development by promoting changes in thought and behavior within daily life; a technique often called ecological momentary intervention (EMI). While EMA/I have become widely employed since the 1980s for the purposes of understanding and promoting change amongst clinical populations, few EMA/I studies have been devoted to understanding or promoting virtues within non-clinical populations. Further, most EMA/I studies have relied on journaling, PDAs, phone calls and/or text messaging systems. We explore how smartphone app technology provides a means of making EMA a more robust psychological method, EMI a more robust way of promoting positive change, and, as a result, opens up new possibilities for studying and promoting virtues. (shrink)

We are living at the dawn of the first truly scientific picture of the universe-as-a-whole, yet people are still dragging along prescientific ideas about God that cannot be true and are even meaningless in the universe we now know we live in. This makes it impossible to have a coherent big picture of the modern world that includes God. But we don't have to accept an impossible God or else no God. We can have a real God if we redefine (...) God in light of knowledge no one ever had before. The key question is, “Could anything actually exist in the scientific universe that is worthy of the name, God?” My answer is yes: God is an “emergent phenomenon,” as real as the global economy or the government or the worldwide web, which are all emergent phenomena. But God arose from something deeper: the complex interactions of all humanity's aspirations. An emerging God has enormous implications. (shrink)

Exposome research is put forward as a major tool for solving the nature-versus-nurture debate because the exposome is said to represent “the nature of nurture.” Against this influential idea, we argue that the adoption of the nature-versus-nurture debate into the exposome research program is a mistake that needs to be undone to allow for a proper bioethical assessment of exposome research. We first argue that this adoption is originally based on an equivocation between the traditional nature-versus-nurture debate and a debate (...) about disease prediction/etiology. Second, due to this mistake, exposome research is pushed to adopt a limited conception of agential control that is harmful to one's thinking about the good that exposome research can do for human health and wellbeing. To fully excise the nature-versus-nurture debate from exposome research, we argue that exposome researchers and bioethicists need to think about the exposome afresh from the perspective of actionability. We define the concept of actionability and related concepts and show how these can be used to analyze the ethical aspects of the exposome. In particular, we focus on refuting the popular “gun analogy” in exposome research, returning results to study participants and risk-taking in the context of a well-lived life. (shrink)

This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of the statement is to complement existing instruments by focusing specifically on institutional responsibilities for strengthening integrity. It takes into account the daily challenges and organisational contexts of most researchers. The statement intends to make research integrity challenges recognisable from the work-floor perspective, providing concrete advice on organisational measures to strengthen integrity. The statement, which was concluded February 7th 2018, provides guidance on (...) the following key issues: § 1. Providing information about research integrity§ 2. Providing education, training and mentoring§ 3. Strengthening a research integrity culture§ 4. Facilitating open dialogue§ 5. Wise incentive management§ 6. Implementing quality assurance procedures§ 7. Improving the work environment and work satisfaction§ 8. Increasing transparency of misconduct cases§ 9. Opening up research§ 10. Implementing safe and effective whistle-blowing channels§ 11. Protecting the alleged perpetrators§ 12. Establishing a research integrity committee and appointing an ombudsperson§ 13. Making explicit the applicable standards for research integrity. (shrink)

Oliva Sabuco's New Philosophy of Human nature (1587) is an early modern philosophy of medicine that challenged the views of the successors to Aristotle, especially Galen and Ibn Sina (Avicenna). It also challenged the paradigm of the male as the epitome of the human and instead offers a gender-neutral philosophy of human nature. Now largely forgotten, it was widely read and influential amongst philosophers of medicine including DeClave, LePois, Harvey,Southey and others, particularly for its account of the role of the (...) nervous system and cerebrospinal fluid in mind-body interaction. In this article I trace its early influence by tracing provenance of the editions produced during the lifetime of its author. (shrink)