Results for 'Embryonic tissue'

156 found
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  1. Who owns embryonic and fetal tissue?Donna Dickenson - 2002 - In Ethical Issues in Maternal-Fetal Medicine. Cambridge University Press. pp. 233-244.
    Until very recently the question of who owns embryonic or fetal tissue was of limited importance to clinicians, but advances in stem cell research have made such tissue commercially valuable. This chapter examines the legal and ethical basis of claims to property in embryonic or fetal tissue, taking a critical stance.
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  2. The global HLA banking of embryonic stem cells requires further scientific justification.Zubin Master & Bryn Williams-Jones - 2007 - American Journal of Bioethics 7 (8):45-46.
    There is a widely acknowledged shortage of and an increasing demand for transplantable human organs and tissues (e.g., kidney, heart, lung, liver, cornea) in developed and developing countries around the world. In response to this need, Lott and Savulescu (2007) propose the creation of a human embryonic stem (hESC) bank to facilitate the equitable and efficient dissemination of human leukocyte anti- gen (HLA) matched tissues and organs to patients in need of replacement. Although not an unreasonable proposal, the authors (...)
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  3. Brains Emerging: On Modularity and Self-organisation of Neural Development In Vivo and In Vitro.Paul Gottlob Layer - 2019 - In Lars H. Wegner & Ulrich Lüttge (eds.), Emergence and Modularity in Life Sciences. Springer Verlag. pp. 145-169.
    Molecular developmental biology has expanded our conceptions of gene actions, underpinning that embryonic development is not only governed by a set of specific genes, but as much by space–time conditions of its developing modules. Typically, formation of cellular spheres, their transformation into planar epithelia, followed by tube formations and laminations are modular steps leading to the development of nervous tissues. Thereby, actions of organising centres, morphogenetic movements, inductive events between epithelia, tissue polarity reversal, widening of epithelia, and all (...)
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  4. Stem Cell Research on Embryonic Persons Is Just.Aaron Rizzieri - 2012 - Journal of Bioethical Inquiry 9 (2):195-203.
    I argue that embryonic stem cell research is fair to the embryo, even on the assumption that the embryo has attained full personhood and an attendant right to life at conception. This is because the only feasible alternatives open to the embryo are to exist briefly in an unconscious state and be killed or to not exist at all. Hence, one is neither depriving the embryo of an enduring life it would otherwise have had nor is one causing the (...)
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  5. Embryonic Afterlives?Amber Griffioen - 2022 - TheoLogica: An International Journal for Philosophy of Religion and Philosophical Theology 8 (1).
    While much has been written on the moral and metaphysical status of fetuses in Christian bioethics, little thought has been given to how we might characterize the afterlives of the unborn, especially of those human biological individuals who die before even developing a body that could theoretically be resurrected. In this paper, I therefore undertake an examination of questions surrounding the afterlife, specifically as it relates to early pregnancy loss. I first lay out what I call the “problem of weird (...)
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  6. In dubio pro embryone. Neue Argumente zum moralischen Status menschlicher Embryonen.Gregor Damschen & Dieter Schönecker - 2003 - In Gregor Damschen & Dieter Schönecker (eds.), Der moralische Status menschlicher Embryonen. Pro und contra Spezies-, Kontinuums-, Identitäts- und Potentiali­tätsargument. Berlin & New York: de Gruyter. pp. 187-267.
    When in doubt, for the embryo. New arguments on the moral status of human embryos. - In the first part of our essay we distinguish the philosophical from the legal and political level of the embryo debate and describe our indirect justification strategy. It consists in renouncing a determination of the dignity-giving φ-properties and instead starting from premises that are undoubted by all discussion partners. In the second part we reconstruct and criticize the species, continuum, identity and potentiality arguments. The (...)
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  7. MACHINE LEARNING IMPROVED ADVANCED DIAGNOSIS OF SOFT TISSUES TUMORS.M. Bavadharani - 2022 - Journal of Science Technology and Research (JSTAR) 3 (1):112-123.
    Delicate Tissue Tumors (STT) are a type of sarcoma found in tissues that interface, backing, and encompass body structures. Due to their shallow recurrence in the body and their extraordinary variety, they seem, by all accounts, to be heterogeneous when seen through Magnetic Resonance Imaging (MRI). They are effortlessly mistaken for different infections, for example, fibro adenoma mammae, lymphadenopathy, and struma nodosa, and these indicative blunders have an extensive unfavorable impact on the clinical treatment cycle of patients. Analysts have (...)
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  8. Digital Analysis of Soft Tissue Nasal Anatomy for Individual Treatment Planning.Hassan Bagheri & Figen Gövsa - 2023 - European Journal of Therapeutics 29 (1):41-48.
    Objective: Changing contour lines of the external nose following traumatic, aesthetic and tumour surgeries have become very trendy. The goal of this research is to study the several soft tissue landmarks, measurements (linear distances, ratios, angles) of the external nose and its nasal indicis using a computer program. Methods: Face region were taken a photographs of the two hundred adults. Analyses of linear (the lengths of nares, nasal bridge, and columella and nose height, nares width) and angular analyses (angles (...)
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  9. Commodification of Human Tissue.Herjeet Marway, Sarah-Louise Johnson & Heather Widdows - 2014 - Handbook of Global Bioethics.
    Commodification is a broad and crosscutting issue that spans debates in ethics (from prostitution to global market practices) and bioethics (from the sale of body parts to genetic enhancement). There has been disagreement, however, over what constitutes commodification, whether it is happening, and whether it is of ethical import. This chapter focuses on one area of the discussion in bioethics – the commodification of human tissue – and addresses these questions – about the characteristics of commodification, its pervasiveness, and (...)
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  10. Judgments of moral responsibility in tissue donation cases.John Beverley & James Beebe - 2017 - Bioethics 32 (2):83-93.
    If a person requires an organ or tissue donation to survive, many philosophers argue that whatever moral responsibility a biological relative may have to donate to the person in need will be grounded at least partially, if not entirely, in biological relations the potential donor bears to the recipient. We contend that such views ignore the role that a potential donor's unique ability to help the person in need plays in underwriting such judgments. If, for example, a sperm donor (...)
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  11. Clarifying how to deploy the public interest criterion in consent waivers for health data and tissue research.G. Owen Schaefer, Graeme Laurie, Sumytra Menon, Alastair V. Campbell & Teck Chuan Voo - 2020 - BMC Medical Ethics 21 (1):1-10.
    Background Several jurisdictions, including Singapore, Australia, New Zealand and most recently Ireland, have a public interest or public good criterion for granting waivers of consent in biomedical research using secondary health data or tissue. However, the concept of the public interest is not well defined in this context, which creates difficulties for institutions, institutional review boards and regulators trying to implement the criterion. Main text This paper clarifies how the public interest criterion can be defensibly deployed. We first explain (...)
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  12. Neuroendocrine study of the Korean native cattle: Pulsatile LHRH release from hypothalamic tissues superfused in vitro.Sun Kyeong Yu - 1989 - Korean Journal of Zoology 32 (3):275-280.
    The present study examined the endogenous release of luteinizing hormone-releasing hormone (LHRH) from superfused hypothalamic slices derived from Korean native cattie (KNC). In addition, the in vitro secretory pattern of LHRH release in '(NC was compared with that in imported cattle such as Holstein cow. The median eminences (ME) of hypothalamic tissues were dissected out, sliced, and quickly placed in an ice-cold superfusion chamber. Superfusion chambers containing ME slices were maintained in a constant temperature water-bath at 37∘C. Effluents were collected (...)
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  13. The afterlife of embryonic persons: what a strange place heaven must be.Timothy F. Murphy - 2012 - Reproductive Biomedicine Online 25:684-688.
    Some commentators argue that conception constitutes the onset of human personhood in a metaphysical sense. This threshold is usually invoked as the basis both for protecting zygotes and embryos from exposure to risks of death in clinical research and fertility medicine and for objecting to abortion, but it also has consequences for certain religious perspectives, including Catholicism whose doctrines directly engage questions of personhood and its meanings. Since more human zygotes and embryos are lost than survive to birth, conferral of (...)
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  14. Stemming the tide of normalisation: An expanded feminist analysis of the ethics and social impact of embryonic stem cell research.Shelley Tremain - 2006 - Journal of Bioethical Inquiry 3 (1-2):33-42.
    Feminists have indicated the inadequacies of bioethical debates about human embryonic stem cell research, which have for the most part revolved around concerns about the moral status of the human embryo. Feminists have argued, for instance, that inquiry concerning the ethics and politics of human embryonic stem cell research should consider the relations of social power in which the research is embedded. My argument is that this feminist work on stem cells is itself inadequate, however, insofar as it (...)
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  15. (1 other version)Ph. Caspar, «L’embryon au IIe siècle». [REVIEW]Jean-François Stoffel - 2003 - Revue des Questions Scientifiques 174 (4):433-434.
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  16. Ethics Surrounding Human Embryonic Stem Cell Research.Joseph Nkang Ogar - 2019 - International Social Mentality and Researcher Thinkers Journal 5 (22).
    Since their discovery in the early 1990s, Stem Cell has brought the prospect of radically improving treatments for a host of diseases such as Alzheimer's, Parkinson's disease, cancers and many among other diseases that currently render patients and scientists helpless to combat. With the advent of medical and scientific research, comes the inevitable emergence of ethical controversy that often accompanied major scientific and medical development. The use of Stem Cell is no different. Those who seek to curtail the use of (...)
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  17. Why the embryo rescue case is a bad argument against embryonic personhood.Perry Hendricks - 2019 - Bioethics 33 (6):669-673.
    The “Embryo Rescue Case” (ERC) refers to a thought experiment that is used to argue against the view that embryos have a right to life (i.e. are persons). I will argue that cognitive science undermines the intuition elicited by the ERC; I will show that whether or not embryos have a right to life, our mental tools will make it very difficult to believe that embryos have said right. This suggests that the intuition elicited by the ERC is not truth (...)
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  18. Paper: Parents' choices in banking boys' testicular tissue.Timothy Murphy - 2010 - Journal of Medical Ethics 36 (12):806-809.
    Researchers are working to derive sperm from banked testicular tissue taken from pre-pubertal boys who face therapies or injuries that destroy sperm production. Success in deriving sperm from this tissue will help to preserve the option for these boys to have genetically related children later in life. For the twin moral reasons of preserving access and equity in regard to having such children, clinicians and researchers are justified in offering the option to the parents of all affected boys. (...)
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  19. Pain as a Secondary Quality: A Phenomenological Approach.Alejandro Escudero-Morales - 2023 - Problemos 103:103-116.
    This work proposes that pain meets the requirements of being characterized as a secondary quality, as it covers, like a color, a determined extension. The argument seeks to establish a literal pain-color analogy through an inquiry into the intensity and location of the pain. From the classic intensity/location relationship reported by patients with acute appendicitis, three degrees of pain are distinguished: mild, moderate, and severe. The objective is only achieved by examining the Body’s extensional determinations (primary quality) insofar as each (...)
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  20. Confessions of a" pro-life" Obama supporter.W. Malcolm Byrnes - 2009 - The National Catholic Bioethics Quarterly 9 (2):241-244.
    The author supported Barack Obama for president, and he agrees with Obama on most issues. However, he opposes the federal funding of human embryonic stem cell (hESC) research. Besides involving the destruction of human life, hESC research can (1) result in the exploitation of women, and (2) cause human reproduction to become a means to an end, i.e., human embryos will become commodities to be bought and sold. Recent scientific developments show the growing potential of induced pluripotent stem (iPS) (...)
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  21. Evidence amalgamation, plausibility, and cancer research.Marta Bertolaso & Fabio Sterpetti - 2019 - Synthese 196 (8):3279-3317.
    Cancer research is experiencing ‘paradigm instability’, since there are two rival theories of carcinogenesis which confront themselves, namely the somatic mutation theory and the tissue organization field theory. Despite this theoretical uncertainty, a huge quantity of data is available thanks to the improvement of genome sequencing techniques. Some authors think that the development of new statistical tools will be able to overcome the lack of a shared theoretical perspective on cancer by amalgamating as many data as possible. We think (...)
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  22. Body Shopping: The Economy Fuelled by Flesh and Blood.Donna Dickenson - 2008 - Oxford: Oneworld.
    'An alarming and illuminating book. The story of how we have allowed private corporations to patent genes, to stockpile human tissue, and in short to make profits out of what many people feel ought to be common goods is a shocking one. No one with any interest at all in medicine and society and how they interact should miss this book, and it should be required reading for every medical student,'--Philip Pullman.
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  23. Biopower, Styles of Reasoning, and What's Still Missing from the Stem Cell Debates.Shelley Tremain - 2010 - Hypatia 25 (3):577 - 609.
    Until now, philosophical debate about human embryonic stem cell (hESC) research has largely been limited to its ethical dimensions and implications. Although the importance and urgency of these ethical debates should not be underestimated, the almost undivided attention that mainstream and feminist philosophers have paid to the ethical dimensions of hESC research suggests that the only philosophically interesting questions and concerns about it are by and large ethical in nature. My argument goes some distance to challenge the assumption that (...)
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  24. Direct Reprogramming and Ethics in Stem Cell Research.W. Malcolm Byrnes - 2008 - The National Catholic Bioethics Quarterly 8 (2):277-290.
    The recent successful conversion of adult cells into induced pluripotent stem (iPS) cells through direct reprogramming opens a new chapter in the study of disease and the development of regenerative medicine. It also provides a historic opportunity to turn away from the ethically problematic use of embryonic stem cells isolated through the destruction of human embryos. Moreover, because iPS cells are patient specific, they render therapeutic cloning unnecessary. To maximize therapeutic benefit, adult stem cell research will need to be (...)
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  25. On Phenomenal Character and Petri Dishes.Gary Bartlett - 2014 - Journal of Philosophical Research 39:67-74.
    Michael Tye (2007) argues that phenomenal character cannot be an intrinsic microphysical property of experiences (or be necessitated by intrinsic microphysical properties) because this would entail that experience could occur in a chunk of tissue in a Petri dish. Laudably, Tye attempts to defend the latter claim rather than resting content with the counter-intuitiveness of the associated image. However, I show that his defense is problematic in several ways, and ultimately that it still amounts to no more than an (...)
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  26. The Hydra model - a model for what?Alfred Gierer - 2012 - International Journal of Developmental Biology 56:437-445.
    The introductory personal remarks refer to my motivations for choosing research projects, and for moving from physics to molecular biology and then to development, with Hydra as a model system. Historically, Trembley’s discovery of Hydra regeneration in 1744 was the begin¬ning of developmental biology as we understand it, with passionate debates about preformation versus de novo generation, mechanisms versus organisms. In fact, seemingly conflicting bottom-up and top-down concepts are both required in combination to understand development. In modern terms, this means (...)
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  27. Unjustified Asymmetry: Positive Claims of Conscience and Heartbeat Bills.Kyle G. Fritz - 2021 - American Journal of Bioethics 21 (8):46-59.
    In 2019, several US states passed “heartbeat” bills. Should such bills go into effect, they would outlaw abortion once an embryonic heartbeat can be detected, thereby severely limiting an individual’s access to abortion. Many states allow health care professionals to refuse to provide an abortion for reasons of conscience. Yet heartbeat bills do not include a positive conscience clause that would allow health care professionals to provide an abortion for reasons of conscience. I argue that this asymmetry is unjustified. (...)
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  28. Knowledge-based Intelligent Tutoring System for Teaching Mongo Database.Mohanad M. Hilles & Samy S. Abu Naser - 2017 - European Academic Research 4 (10).
    Recently, Intelligent Tutoring Systems (ITS) got much attention from researchers even though ITS educational technology began in the late 1960s and ITS is just embryonic from laboratories into the field. In this paper we outline an intelligent tutoring system for teaching basics of the databases system called (MDB). The MDB was built as education system by using the authoring tool (ITSB). MDB contains learning materials as a group of lessons for beginner level which include relational database system and lessons (...)
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  29. Pemanfaatan Sel Punca Embrionik dalam Pengembangan Bioteknologi Menurut Pandangan Hukum Islam.Moch Najib Yuliantoro - 2017 - In Yuliantoro Moch Najib (ed.), 9 Studi Kasus Hukum Islam Kontemporer. Pondok Pesantren Universitas Islam Indonesia. pp. 2-20.
    Pemanfaatan sel punca embrionik (Embryonic Stem Cells/ESCs) telah menjadi isu global dalam bidang bioteknologi modern yang selalu memicu perdebatan mendalam dari berbagai ilmuwan, filosof, agamawan, ahli hukum dan praktisi politik. Penelitian ini membahas gambaran umum dan manfaat sel punca embrionik, serta menganalisisnya berdasarkan pandangan hukum Islam. Metode yang digunakan adalah studi pustaka multidisiplin dari teks-teks ilmu medis, etika dan hukum Islam. Hasil penelitian ini menunjukkan bahwa meskipun masih terdapat perbedaan pandangan dari para ahli hukum Islam tentang kapan awal mula (...)
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  30. Metaphysical and Moral Status of Cryopreserved Embryos.Jason T. Eberl - 2012 - The Linacre Quarterly 79 (3):304-315.
    Those who oppose human embryonic stem cell research argue for a clear position on the metaphysical and moral status of human embryos. This position does not differ whether the embryo is present inside its mother’s reproductive tract or in a cryopreservation tank. It is worth examining, however, whether an embryo in “suspended animation” has the same status as one actively developing in utero. I will explore this question from the perspective of Thomas Aquinas’s metaphysical account of human nature. I (...)
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  31. Multiplex parenting: IVG and the generations to come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the feasibility of IVG derivation (...)
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  32. Thomistic Principles and Bioethics.Jason T. Eberl - 2006 - New York: Routledge.
    Alongside a revival of interest in Thomism in philosophy, scholars have realised its relevance when addressing certain contemporary issues in bioethics. This book offers a rigorous interpretation of Aquinas's metaphysics and ethical thought, and highlights its significance to questions in bioethics. Jason T. Eberl applies Aquinas’s views on the seminal topics of human nature and morality to key questions in bioethics at the margins of human life – questions which are currently contested in the academia, politics and the media such (...)
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  33. Property in the Body: Feminist Perspectives.Donna Dickenson - 2007 - Cambridge University Press.
    New developments in biotechnology radically alter our relationship with our bodies. Body tissues can now be used for commercial purposes, while external objects, such as pacemakers, can become part of the body. Property in the Body: Feminist Perspectives transcends the everyday responses to such developments, suggesting that what we most fear is the feminisation of the body. We fear our bodies are becoming objects of property, turning us into things rather than persons. This book evaluates how well-grounded this fear is, (...)
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  34. Biomedical imaging ontologies: A survey and proposal for future work.Barry Smith, Sivaram Arabandi, Mathias Brochhausen, Michael Calhoun, Paolo Ciccarese, Scott Doyle, Bernard Gibaud, Ilya Goldberg, Charles E. Kahn Jr, James Overton, John Tomaszewski & Metin Gurcan - 2015 - Journal of Pathology Informatics 6 (37):37.
    Ontology is one strategy for promoting interoperability of heterogeneous data through consistent tagging. An ontology is a controlled structured vocabulary consisting of general terms (such as “cell” or “image” or “tissue” or “microscope”) that form the basis for such tagging. These terms are designed to represent the types of entities in the domain of reality that the ontology has been devised to capture; the terms are provided with logical defi nitions thereby also supporting reasoning over the tagged data. Aim: (...)
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  35. A theory of biological pattern formation.Alfred Gierer & Hans Meinhardt - 1972 - Kybernetik, Continued as Biological Cybernetics 12 (1):30 - 39.
    The paper addresses the formation of striking patterns within originally near-homogenous tissue, the process prototypical for embryology, and represented in particularly purist form by cut sections of hydra regenerating, by internal reorganisation of the pre-existing tissue, a complete animal with head and foot. The essential requirements are autocatalytic, self-enhancing activation, combined with inhibitory or depletion effects of wider range – “lateral inhibition”. Not only de-novo-pattern formation, but also well known, striking features of developmental regulation such as induction, inhibition, (...)
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  36. The epistemic costs of compromise in bioethics.Katrien Devolder & Thomas Douglas - 2017 - Bioethics 32 (2):111-118.
    Bioethicists sometimes defend compromise positions, particularly when they enter debates on applied topics that have traditionally been highly polarised, such as those regarding abortion, euthanasia and embryonic stem cell research. However, defending compromise positions is often regarded with a degree of disdain. Many are intuitively attracted to the view that it is almost always problematic to defend compromise positions, in the sense that we have a significant moral reason not to do so. In this paper, we consider whether this (...)
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  37.  81
    In Vitro Analogies: Simulation Modeling in Bioengineering Sciences.Nancy Nersessian - forthcoming - In Tarja Knuuttila, Natalia Carrillo & Rami Koskinen (eds.), Routledge Handbook of Scientific Modeling. Routledge.
    This chapter focuses on a novel class of models used in frontier research in the bioengineering sciences – in vitro simulation models – that provide the basis for biological experimentation. These bioengineered models are hybrid constructions, composed of living tissues or cells and engineered materials. Specifically, it discusses the processes through which in vitro models were built, experimented with, and justified in a tissue engineering lab. It examines processes of design, construction, experimentation, evaluation, and redesign of in vitro simulation (...)
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  38. Epigenesis as Spinozism in Diderot’s biological project (draft).Charles T. Wolfe - 2014 - In Ohad Nachtomy & Justin E. H. Smith (eds.), The Life Sciences in Early Modern Philosophy. New York, NY: Oup Usa. pp. 181-201.
    Denis Diderot’s natural philosophy is deeply and centrally ‘biologistic’: as it emerges between the 1740s and 1780s, thus right before the appearance of the term ‘biology’ as a way of designating a unified science of life (McLaughlin), his project is motivated by the desire both to understand the laws governing organic beings and to emphasize, more ‘philosophically’, the uniqueness of organic beings within the physical world as a whole. This is apparent both in the metaphysics of vital matter he puts (...)
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  39. Computer-assisted argument mapping: A Rationale Approach.Martin Davies - 2009 - Higher Education 58:799-820.
    Computer-Assisted Argument Mapping (CAAM) is a new way of understanding arguments. While still embryonic in its development and application, CAAM is being used increasingly as a training and development tool in the professions and government. Inroads are also being made in its application within education. CAAM claims to be helpful in an educational context, as a tool for students in responding to assessment tasks. However, to date there is little evidence from students that this is the case. This paper (...)
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  40. On decoding and rewriting genomes: a psychoanalytical reading of a scientific revolution.Hub Zwart - 2012 - Medicine, Health Care and Philosophy 15 (3):337-346.
    In various documents the view emerges that contemporary biotechnosciences are currently experiencing a scientific revolution: a massive increase of pace, scale and scope. A significant part of the research endeavours involved in this scientific upheaval is devoted to understanding and, if possible, ameliorating humankind: from our genomes up to our bodies and brains. New developments in contemporary technosciences, such as synthetic biology and other genomics and “post-genomics” fields, tend to blur the distinctions between prevention, therapy and enhancement. An important dimension (...)
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  41. Roleplaying Game–Based Engineering Ethics Education: Lessons from the Art of Agency.Trystan S. Goetze - 2024 - Proceedings of the 2024 American Society for Engineering Education St. Lawrence Section Annual Conference.
    How do we prepare engineering students to make ethical and responsible decisions in their professional work? This paper presents an approach that enhances engineering students’ engagement with ethical reasoning by simulating decision-making in a complex scenario. The approach has two principal inspirations. The first is Anthony Weston’s scenario-based teaching. Weston’s concept of a scenario is a situation that changes in response to choices made by participants, according to an inner logic. Scenarios can dynamically explore open-ended complex problems without imposing predetermined (...)
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  42. Accumulation of potentially toxic elements in fourfinger threadfin (Eleutheronema tetradactylum) and black pomfret (Parastromateus niger) from Selangor, Malaysia.Chuck Chuan Ng - 2024 - Environmental Monitoring and Assessment 196 (382).
    The accumulation of potentially toxic elements (PTEs) has raised public awareness due to harmful contamination to both human and marine creatures. This study was designed to determine the concentration of copper (Cu), zinc (Zn), cadmium (Cd), and nickel (Ni) in the intestine, kidney, muscle, gill, and liver tissues of local commercial edible fish, fourfinger threadfin (Eleutheronema tetradactylum), and black pomfret (Parastromateus niger) collected from Morib (M) and Kuala Selangor (KS). Among the studied PTEs, Cu and Zn were essential elements to (...)
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  43. Unintended Intrauterine Death and Preterm Delivery: What Does Philosophy Have to Offer?Nicholas Colgrove - 2023 - Journal of Medicine and Philosophy 48 (3):195-208.
    This special issue of the Journal of Medicine and Philosophy focuses on unintended intrauterine death (UID) and preterm delivery (both phenomena that are commonly—and unhelpfully—referred to as “miscarriage,” “spontaneous abortion,” and “early pregnancy loss”). In this essay, I do two things. First, I outline contributors’ arguments. Most contributors directly respond to “inconsistency arguments,” which purport to show that abortion opponents are unjustified in their comparative treatment of abortion and UID. Contributors to this issue show that such arguments often rely on (...)
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  44. Four Ways from Universal to Particular: How Chomsky's Language-Acquisition Faculty is Not Selectionist.David Ellerman - 2016 - Journal of Applied Non-Classical Logics 3 (26):193-207.
    Following the development of the selectionist theory of the immune system, there was an attempt to characterize many biological mechanisms as being "selectionist" as juxtaposed to "instructionist." But this broad definition would group Darwinian evolution, the immune system, embryonic development, and Chomsky's language-acquisition mechanism as all being "selectionist." Yet Chomsky's mechanism (and embryonic development) are significantly different from the selectionist mechanisms of biological evolution or the immune system. Surprisingly, there is a very abstract way using two dual mathematical (...)
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  45. That is life: communicating RNA networks from viruses and cells in continuous interaction.Guenther Witzany - 2019 - Annals of the New York Academy of Sciences:1-16.
    All the conserved detailed results of evolution stored in DNA must be read, transcribed, and translated via an RNAmediated process. This is required for the development and growth of each individual cell. Thus, all known living organisms fundamentally depend on these RNA-mediated processes. In most cases, they are interconnected with other RNAs and their associated protein complexes and function in a strictly coordinated hierarchy of temporal and spatial steps (i.e., an RNA network). Clearly, all cellular life as we know it (...)
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  46. (1 other version)Making Sense of Downward Causation in Manipulationism (with illustrations from cancer research).Christophe Malaterre - 2011 - History and Philosophy of the Life Sciences (33):537-562.
    Many researchers consider cancer to have molecular causes, namely mutated genes that result in abnormal cell proliferation (e.g. Weinberg 1998). For others, the causes of cancer are to be found not at the molecular level but at the tissue level where carcinogenesis consists of disrupted tissue organization with downward causation effects on cells and cellular components (e.g. Sonnenschein and Soto 2008). In this contribution, I ponder how to make sense of such downward causation claims. Adopting a manipulationist account (...)
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  47. The Limitations of Hierarchical Organization.Angela Potochnik & Brian McGill - 2012 - Philosophy of Science 79 (1):120-140.
    The concept of hierarchical organization is commonplace in science. Subatomic particles compose atoms, which compose molecules; cells compose tissues, which compose organs, which compose organisms; etc. Hierarchical organization is particularly prominent in ecology, a field of research explicitly arranged around levels of ecological organization. The concept of levels of organization is also central to a variety of debates in philosophy of science. Yet many difficulties plague the concept of discrete hierarchical levels. In this paper, we show how these difficulties undermine (...)
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  48. (2 other versions)The harder problem of consciousness.Ned Block - 2002 - Journal of Philosophy 99 (8):391-425.
    consciousness comes about as a result of irritating nervous tissue, is just as unaccountable as the appearance of Djin when Aladdin rubbed his lamp.
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  49. Can there be a global Demos? An agency-based approach.Christian List & Mathias Koenig-Archibugi - 2010 - Philosophy and Public Affairs 38 (1):76-110.
    Can there be a global demos? The current debate about this topic is divided between two opposing camps: the “pessimist” or “impossibilist” camp, which holds that the emergence of a global demos is either conceptually or empirically impossible, and the “optimist” or “possibilist” camp, which holds that the emergence of a global demos is conceptually as well as empirically possible and an embryonic version of it already exists. However, the two camps agree neither on a common working definition of (...)
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  50. Coherent Causal Control: A New Distinction within Causation.Marcel Weber - 2022 - European Journal for Philosophy of Science 12 (4):69.
    The recent literature on causality has seen the introduction of several distinctions within causality, which are thought to be important for understanding the widespread scientific practice of focusing causal explanations on a subset of the factors that are causally relevant for a phenomenon. Concepts used to draw such distinctions include, among others, stability, specificity, proportionality, or actual-difference making. In this contribution, I propose a new distinction that picks out an explanatorily salient class of causes in biological systems. Some select causes (...)
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