Region R Question: How many objects — entities, things — are contained in R? Ignore the empty space. Our question might better be put, 'How many material objects does R contain?' Let's stipulate that A, B and C are metaphysical atoms: absolutely simple entities with no parts whatsoever besides themselves. So you don't have to worry about counting a particle's top half and bottom half as different objects. Perhaps they are 'point-particles', with no length, width or breadth. Perhaps they are (...) extended in space without possessing spatial parts (if that is possible). Never mind. We stipulate that A, B and C are perfectly simple. We also stipulate that they are connected as follows. A and B are stuck together in such a way that when a force is applied to one of them, they move together 'as a unit'. Moreover, the two of them together exhibit behavior that neither would exhibit on its own — Perhaps they emit a certain sound, or glow in the dark — whereas C is.. (shrink)

Frequently, those who commit a crime forcibly are subject to greater punishment than those who commit the same crime without using force. But uncertainty surrounds the conditions that must be met for an act to be performed with force. It is particularly puzzling that acts that are committed through threat, which are in no way harmful, are nonetheless classified under the law as forcibly committed. This paper explains why by offering an account of a particular kind of harmless force. On (...) the account offered, an act is performed with this type of force just in case it manifests a disposition to escalate in the face of obstacles permissibly imposed by the victim. The paper argues that conduct that manifests such a disposition causes the victim’s agency to be implicated in the wrong done to them by causing them to refrain from realizing obstacles to the wrong. Forcible conduct, therefore, invades another’s autonomy in a way that non-forcible conduct does not and is, for that reason, more wrongful. (shrink)

According to one sort of epistemic relativist, normative epistemic claims (e.g., evidence E justifies hypothesis H) are never true or false simpliciter, but only relative to one or another epistemic system. In chapter 6 of Fear of Knowledge, Paul Boghossian objects to this view on the ground that its central notions cannot be explained, and that it cannot account for the normativity of epistemic discourse. This paper explores how the dogged relativist might respond.

In this paper, I propose an account of Camus’s ethics in which violent revolutions are never morally permissible but nonetheless acceptable or necessary. My main thesis in this paper is that Camus’s ethics of revolution and my defence of it, particularly the non-moral account of the permissibility of violent revolutions it comprises, can shed light on the reasonableness of participating in and supporting violent revolutions to some Catholics and the broader Christian community. My account of Camus’s ethics of revolution and (...) argument for its tenability will be compelling to some Catholics because they affirm their intuition that violent revolutions are morally untenable and show why it is nevertheless reasonable. (shrink)

The family poses problems for liberal understandings of social justice, because of the ways in which it bestows unearned privileges. This is particularly stark when we consider inter-generational inequality, or ‘class fate’ – the ways in which inequality is transmitted from one generation to the next, with the family unit ostensibly a key conduit. There is a recognized tension between the assumption that families should as far as possible be autonomous spheres of decision-making, and the assumption that we should as (...) far as possible equalize the life chances of all children, regardless of background. In this article I address this tension by way of recent liberal egalitarian literature, and consideration of the different dimensions of class fate. I argue, firstly, that the tension may not be of the a priori nature which liberals have tended to identify – and secondly, that as well as distributive and recognition-based aspects, the notion of contributive justice provides a particularly illuminating way of analyzing what is wrong about class fate, and the role of the family in promoting it. (shrink)

This paper takes up a neglected problem for metaethical noncognitivism: the characterization of the acceptance states for agent-centered normative theories like Rational Egoism. If Egoism is a coherent view, the non-cognitivist needs a coherent acceptance state for it. This can be provided, as Dreier and Gibbard have shown. But those accounts fail when generalized, assigning the same acceptance state to normative theories that are clearly distinct, or assigning no acceptance state to theories that look to be intelligible. The paper makes (...) the case for this and then asks: What should we conclude if the problem cannot be solved? We might conclude that since Egoism is clearly a coherent view, the argument amounts to a refutation of noncognitivism. But we suggest another possibility. There is, on reflection, something incoherent, or at least odd, in standard formulations of Egoism; noncognitivism predicts this and so provides an intriguing explanation for this fact. (shrink)

We present a rigorous way to evaluate the visual perception of correlation in scatterplots, based on classical psychophysical methods originally developed for simple properties such as brightness. Although scatterplots are graphically complex, the quantity they convey is relatively simple. As such, it may be possible to assess the perception of correlation in a similar way. Scatterplots were each of 5.0 extent, containing 100 points with a bivariate normal distribution. Means were 0.5 of the range of the points, and standard deviations (...) 0.2 of this range. Precision was determined via an adaptive algorithm to find the just noticeable differences (jnds) in correlation, i.e., the difference between two side-by-side scatterplots that could be discriminated 75% of the time. Accuracy was measured by direct estimation, using reference scatterplots with fixed upper and lower values, with a test scatterplot adjusted so that its correlation appeared to be halfway between these. This process was recursively applied to yield several further estimates. Results of the discrimination tests show jnd(r) = k (1/b – r), where r is the Pearson correlation, and parameters 0 < k, b < 1. Integration yields a subjective estimate of correlation g(r) = ln(1 – br) / ln(1– b). The values of b found via discrimination closely match those found via direct estimation. As such, it appears that the perception of correlation in a scatterplot is completely described by two related performance curves, specified by two easily-measured parameters. (shrink)

Reid argues that Hume’s claim that justice is an artificial virtue is inconsistent with the fact that gratitude is a natural sentiment. This chapter shows that Reid’s argument succeeds only given a philosophy of mind and action that Hume rejects. Among other things, Reid assumes that one can conceive of one of a pair of contradictories only if one can conceive of the other—a claim that Hume denies. So, in the case of justice, the disagreement between Hume and Reid is, (...) at bottom, a disagreement over their respective conceptions of how the human mind works at its most fundamental level. (shrink)

Childhood looms large in our understanding of human life as it is a phase through which all adults have passed. Childhood is foundational to the development of selfhood, the formation of interests, values and skills and to the lifespan as a whole. Understanding what it is like to be a child, and what differences childhood makes, are essential for any broader understanding of the human condition. The Routledge Handbook of the Philosophy of Childhood and Children is an outstanding reference source (...) to the key topics, problems and debates in this exciting subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors the Handbook is divided into five parts: ¿ Being a child ¿ Childhood and moral status ¿ Parents and children ¿ Children in society ¿ Children and the state. Questions covered include: What is a child? Is childhood a uniquely valuable state, and if so why? Can we generalize about the goods of childhood? What rights do children have, and are they different from adults¿ rights? What gives people a right to parent? What role, if any, ought biology to play in determining who has the right to parent a particular child? What kind of rights can parents legitimately exercise over their children? What roles do relationships with siblings and friends play in the shaping of childhoods? How should we think about sexuality and disabilility in childhood, and about racialised children? How should society manage the education of children, and what values should inform such practices? What is a good school? How are children¿s lives affected by being taken into social care? The Routledge Handbook of the Philosophy of Childhood and Children is essential reading for students and researchers in philosophy of childhood, political philosophy and ethics as well as those in related disciplines such as education, psychology, sociology, social policy, law, social work, youth work, neuroscience and anthropology. (shrink)

O desempenho das empresas tem sido estudado sob diferentes perspectivas teóricas, que, em geral a utilizam indicadores econômico-financeiros. Essa abordagem sofre constantes críticas por não contemplar aspectos estratégicos, que podem fornecer informações acerca de vantagem competitiva obtida pela empresa. Fatores macroeconômicos também tendem a impactar de maneira indireta os diferentes setores. Além disso, os setores sofrem esses impactos macroeconômicos conforme o nível de exposição deste às oscilações macroeconômicas. Assim este trabalho buscou analisar como as dimensões de desempenho se relacionam com (...) retorno, para cada setor da bolsa de valores. Para a análise, utilizou-se a modelagem de equações estruturais a partir do software Smart-PLS. Foram utilizados dados do Economática para 82 empresas listadas em 6 setores da B3 no período entre 2011 e 2018. Os resultados indicam que diferentes indicadores compõe os construtos para cada setor analisado, indicando que o retorno tem associações diferentes em cada setor. O construto econômico-financeiro apresenta uma relação positiva na explicação dos retornos para os diferentes setores. Já o construto estratégico relacionou-se positivamente apenas no setor de Materiais Básicos. A dimensão macroeconômica apresentou resultados que evidenciam uma relação negativa com os retornos no período analisado. Assim pode-se apontar que o retorno de cada setor é explicado por diferentes informações, sugerindo que o investidor deve observar critérios específicos de cada setor. Os indicadores macroeconômicos foram similares para os setores analisados, contudo o impacto significativo não pode ser verificado para todos os setores, indicando que existem níveis de exposição diferentes para os setores. Ainda, foram evidenciados tanto efeitos diretos quanto indiretos dos indicadores macroeconômicos sobre o retorno. (shrink)

Review of Yaffe's "The Age of Culpability".

Gideon Rosen and Robert Schwartzkopff have independently suggested (variants of) the following claim, which is a varian of Hume's Principle: -/- When the number of Fs is identical to the number of Gs, this fact is grounded by the fact that there is a one-to-one correspondence between the Fs and Gs. -/- My paper is a detailed critique of the proposal. I don't find any decisive refutation of the proposal. At the same time, it has some consequences which many (...) will find objectionable. (shrink)

The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health. IDO Core is designed to be a disease and pathogen neutral ontology, covering just those types of entities and relations that are relevant to infectious diseases generally. IDO Core is then extended by a collection of ontology modules focusing on specific diseases and pathogens. In this paper we (...) present applications of IDO Core within various areas of infectious disease research, together with an overview of all IDO extension ontologies and the methodology on the basis of which they are built. We also survey recent developments involving IDO, including the creation of IDO Virus; the Coronaviruses Infectious Disease Ontology (CIDO); and an extension of CIDO focused on COVID-19 (IDO-CovID-19).We also discuss how these ontologies might assist in information-driven efforts to deal with the ongoing COVID-19 pandemic, to accelerate data discovery in the early stages of future pandemics, and to promote reproducibility of infectious disease research. (shrink)

Technological developments have resulted in tremendous increases in the volume and diversity of the data and information that must be processed in the course of biomedical and clinical research and practice. Researchers are at the same time under ever greater pressure to share data and to take steps to ensure that data resources are interoperable. The use of ontologies to annotate data has proven successful in supporting these goals and in providing new possibilities for the automated processing of data and (...) information. In this chapter, we describe different types of vocabulary resources and emphasize those features of formal ontologies that make them most useful for computational applications. We describe current uses of ontologies and discuss future goals for ontology-based computing, focusing on its use in the field of infectious diseases. We review the largest and most widely used vocabulary resources relevant to the study of infectious diseases and conclude with a description of the Infectious Disease Ontology (IDO) suite of interoperable ontology modules that together cover the entire infectious disease domain. (shrink)

A repository of clinically associated Staphylococcus aureus (Sa) isolates is used to semi‐automatically generate a set of application ontologies for specific subfamilies of Sa‐related disease. Each such application ontology is compatible with the Infectious Disease Ontology (IDO) and uses resources from the Open Biomedical Ontology (OBO) Foundry. The set of application ontologies forms a lattice structure beneath the IDO‐Core and IDO‐extension reference ontologies. We show how this lattice can be used to define a strategy for the construction of a new (...) taxonomy of infectious disease incorporating genetic, molecular, and clinical data. We also outline how faceted browsing and query of annotated data is supported using a lattice application ontology. (shrink)

In ‘Excusing Mistakes of Law’, Gideon Yaffe sets out to ‘vindicate’ the claim ‘that mistakes of law never excuse’ by ‘identifying the truth that is groped for but not grasped by those who assert that ignorance of law is no excuse’. Yaffe does not offer a defence of the claim that mistakes of law never excuse. That claim, Yaffe argues, is false. Yaffe’s article is, rather, an effort to assess what plausible thought might be behind the idea that mistakes (...) of law often should not excuse. (Yaffe is interested in more than just the descriptive claim that in Anglo-American legal jurisdictions mistakes of law routinely do not, in fact, excuse.) More particularly, Yaffe is interested in what plausible normative justification there might be for this asymmetric pattern: -/- Asymmetry: False beliefs about non-legal facts often excuse, but false beliefs about the law rarely excuse. -/- Yaffe offers a complex argument in support of Asymmetry. This paper is organised around my reconstruction of Yaffe’s argument. I argue that Yaffe’s argument does not succeed, but that his argument provides a template for an argument that could succeed. (shrink)

‘Attempted negligence’ is a category of criminal offense that many jurists and philosophers have law have deemed conceptually incoherent. In his Attempts: In the Philosophy of Action and the Criminal Law, Gideon Yaffe challenges this dismissal, anchoring his argument in cases of what he calls ‘mental self-management’ in which agents plan to bring about that they perform unintentional actions at a later time. He plausibly argues that mental self-management-type attempted negligence is possible. However, his account raises the question whether (...) such attempts can be successful: whether, in other words, attempts to perform unintentional actions at a later time could issue in actions that are, indeed, unintentional. Intuitively, at least, it would seem that we should answer in the affirmative. However, that answer poses problems for a plausible and widely-held account of intentional action. Al Mele, responding to Yaffe’s account, has pointed out this problem without, I think, providing a satisfactory resolution. I propose another way of vindicating the possibility of successful attempted negligence with small, if significant, revision to the standard view of intentional action. In these cases, I argue, agents fail to act intentionally because they render themselves, through their acts of self-management, unaware that they are successfully executing their intentions. Moreover, I argue that these agents’ intentions to bring about that they perform unintentional actions do not commit them to acting intentionally because of the nature of intentions to bring about actions. I offer an account of the intention to bring about that one A’s and defend it against some objections. (shrink)

Gideon Rosen has recently sketched an argument which aims to establish that the notion of metaphysical modality is systematically ambiguous. His argument contains a crucial sub-argument which has been used to argue for Metaphysical Contingentism, the view that some claims of fundamental metaphysics are metaphysically contingent rather than necessary. In this paper, Rosen’s argument is explicated in detail and it is argued that the most straight-forward reconstruction fails to support its intended conclusion. Two possible ways to save the argument (...) are rebutted and it is furthermore argued that the crucial sub-argument only supports a rather particular variant of Metaphysical Contingentism. (shrink)

According to truthmaker theory, particular truths are true in virtue of the existence of particular entities. Truthmaker maximalism holds that this is so for all truths. Negative existential and other ‘negative’ truths threaten the position. Despite this, maximalism is an appealing thesis for truthmaker theorists. This motivates interest in parsimonious maximalist theories, which do not posit extra entities for truthmaker duty. Such theories have been offered by David Lewis and Gideon Rosen, Ross Cameron, and Jonathan Schaffer. But these theories (...) cannot be sustained, I’ll argue, and hence maximalism comes with a serious ontological cost. Neither Armstrong’s invocation of totality facts nor the Martin-Kukso line on absences can meet this cost satisfactorily. I’ll claim that negative facts are the best (and perhaps only) way out of the problem for the truthmaker maximalist. (shrink)

When we define something as a crime, we generally thereby criminalize the attempt to commit that crime. However, it is a vexing puzzle to specify what must be the case in order for a criminal attempt to have occurred, given that the results element of the crime fails to come about. I argue that the philosophy of action can assist the criminal law in clarifying what kinds of events are properly categorized as criminal attempts. A natural thought is that this (...) project should take the form of specifying what it is in general to attempt or try to perform an action, and then to define criminal attempts as attempts to commit crimes. Focusing on Gideon Yaffe's resourceful work in Attempts (Oxford University Press, 2010) as an example of this strategy, I argue that it results in a view that is overly inclusive: one will count as trying to commit a crime even in the far remote preparatory stages that we in fact have good reason not to criminalize. I offer an alternative proposal to distinguish between mere preparations and genuine attempts that has its basis not in trying, but doing: a criminal attempt is underway once what the agent is doing is a crime. Working out the details of this schema turns out to have important implications for action theory. A recently burgeoning view known as Naive Action Theory holds that all action can be explained by appeal to some further thing that the agent is doing, and that that the same explanatory nexus is at work even when we appeal to what the agent is intending, trying, or preparing to do -- these notions do explanatory work because they too refer to actions that are in progress, albeit in their infancy. If this is right, than the notion of 'doing' will also be too inclusive for the purposes of the criminal law. I argue that we should draw the reverse conclusion: the distinctions between pure intending, trying, preparing, and doing serve an important purpose in the criminal law, and this fact lends support to the view that they are genuine metaphysical and explanatory distinctions. (shrink)

In this paper I defend the traditional interpretations of Kant’s Formula of a Law of Nature from recent attacks leveled by Faviola Rivera-Castro, James Furner, Ido Geiger, Pauline Kleingeld and Sven Nyholm. After a short introduction, the paper is divided into four main sections. In the first, I set out the basics of the three traditional interpretations, the Logical Contradiction Interpretation, the Practical Contradiction Interpretation and the Teleological Contradiction Interpretation. In the second, I examine the work of Geiger, Kleingeld and (...) Nyholm: these three commentators reject the traditional interpretations entirely, but I argue that this rejection is ill-founded. In the third and fourth, I take a detailed look at Furner’s work, work in which he seeks to revise (rather than reject) the traditional interpretations. I argue that, despite his more modest aims, Furner’s revision is also ill-founded. (shrink)

Recently, a number of authors have suggested that the epistemic condition on moral responsibility makes blameworthiness much less common than we ordinarily suppose, and much harder to identify. This paper argues that such epistemically based responsibility skepticism is mistaken. Section 2 sketches a general account of moral responsibility, building on the Strawsonian idea that blame and credit relates to the agent’s quality of will. Section 3 explains how this account deals with central cases that motivate epistemic skepticism and how it (...) avoids some objections to quality of will accounts recently raised by Gideon Rosen. But an intuitive worry brought out by these objections remains. Section 4 spells out this remaining worry and argues that, like traditional metaphysical responsibility skepticism, it has its source in a non-standard explanatory perspective on action, suggesting that strategies for explaining away the intuitive pull of traditional skepticism are applicable in this case too. (shrink)

El propósito de esta investigación es tratar de hacer una aproximación al pensamiento metafísico de Nicolás de Cusa partiendo de su libro La caza de la sabiduría, en las siguientes fases: 1. En primer lugar, pretendo contextualizar al autor, principalmente aquellos aspectos que han marcado notoriamente su pensamiento, como son por ejemplo el comienzo del renacimiento, su papel en la defensa de la unidad de la iglesia, la presencia del pensamiento aristotélico y platónico en la época en que vivió, etc. (...) Trato de destacar lo que considera las claves hermenéuticas para la comprensión de su pensamiento filosófico. 2. A continuación, analizo los temas tratados en esta obra, remarcando las grandes cuestiones Cusanas, a medida que van siendo incoadas. Cito algunas de las discusiones planteadas en la bibliografía referentes a la interpretación que diferentes autores han ido haciendo, y trato de aportar luces tras la lectura e interpretación del libro La caza de la sabiduría. 3. Finalmente presento una serie de conclusiones con mi parecer personal acerca de algunas de las cuestiones más debatidas en la bibliografía consultada. (shrink)

The Brock-Rosen problem has been one of the most thoroughly discussed objections to the modal fictionalism bruited in Gideon Rosen’s ‘Modal Fictionalism’. But there is a more fundamental problem with modal fictionalism, at least as it is normally explained: the position does not resolve the tension that motivated it. I argue that if we pay attention to a neglected aspect of modal fictionalism, we will see how to resolve this tension—and we will also find a persuasive reply to the (...) Brock-Rosen objection. Finally, I discuss an alternative reading of Rosen, and argue that this position is also able to fend off the Brock-Rosen objection. (shrink)

This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. The treatments of resistance terms in various existing ontologies are examined and found to be either overly narrow, internally inconsistent, or otherwise problematic. We propose a more coherent characterization of resistance in terms of what we shall call blocking dispositions, which are collections of mutually coordinated dispositions which are of such a sort that they cannot undergo simultaneous realization within a single (...) bearer. A definition of ‘protective resistance’ is proposed for use in the Infectious Disease Ontology (IDO) and we show how this definition can be used to characterize the antibiotic resistance in Methicillin-Resistant Staphylococcus aureus (MRSA). The ontological relations between entities in our MRSA case study are used alongside a series of logical inference rules to illustrate logical reasoning about resistance. A description logic representation of blocking dispositions is also provided. We demonstrate that our characterization of resistance is sufficiently general to cover two other cases of resistance in the infectious disease domain involving HIV and malaria. (shrink)

La literatura sobre razonamiento probatorio busca incidir en la determinación de los hechos en los procesos judiciales. Para alcanzar dicho propósito, no basta con dirigir la mirada hacia disciplinas extrajurídicas exitosas e integrar lo que de ellas pueda extraerse a las teorías jurídicas de la prueba y a la práctica judicial. Es necesario, además, considerar el tipo de hechos a probar, los roles de las reglas jurídicas aplicables, y asumir que litigantes y jueces, actuando en un contexto institucional, podrán ser (...) más o menos agudos en la discusión fáctica, entre otras cosas. Minimizar la influencia de tales factores expone a los estudios probatorios a tener un bajo rendimiento práctico. Algo de esto ha ocurrido con la llamada concepción racionalista de la prueba. Su innegable aporte al debate académico en español no ha ido a la par de su impacto judicial. Para explicar esta brecha entre teoría y práctica, identificamos tres creencias-obstáculo que afectan a su discurso sobre la prueba y que deben ser sorteadas si lo que se busca es influir en la forma en que se juzgan los hechos en un sistema judicial realmente existente. (shrink)

This paper addresses the use of dispositions in the Infectious Disease Ontology (IDO). IDO is an ontology constructed according to the principles of the Open Biomedical Ontology (OBO) Foundry and uses the Basic Formal Ontology (BFO) as an upper ontology. After providing a brief introduction to disposition types in BFO and IDO, we discuss three general techniques for representing combinations of dispositions under the headings blocking dispositions, complementary dispositions, and collective dispositions. Motivating examples for each combination of dispositions is given (...) along with a specific use case in IDO. Description logic restrictions are used to formalize statements relating to these combinations. (shrink)

In this paper, I describe and motivate a new species of mathematical structuralism, which I call Instrumental Nominalism about Set-Theoretic Structuralism. As the name suggests, this approach takes standard Set-Theoretic Structuralism of the sort championed by Bourbaki and removes its ontological commitments by taking an instrumental nominalist approach to that ontology of the sort described by Joseph Melia and Gideon Rosen. I argue that this avoids all of the problems that plague other versions of structuralism.

A recent methodological approach at the interface of metaphysics and philosophy of science suggests that just like causal laws govern causation, there needs to be something in metaphysics that governs metaphysical relations. Such laws of metaphysics would be counterfactual-supporting general principles that account for the explanatory force of metaphysical explanations. There are various suggestions about how such principles could be understood. They could be based on what Kelly Trogdon calls grounding-mechanical explanations, where the role that grounding mechanisms play in certain (...) metaphysical explanations mirrors the role that causal mechanisms play in certain scientific explanations. Another approach, by Gideon Rosen, takes it that there are essentialist principles or laws that tell us about what grounds what. Finally, Jonathan Schaffer defends an approach that he considers to be neutral regarding grounding or essences. In this paper I will assess these suggestions and argue that for those willing to invoke a non-modal notion of essence, there is a more promising route available: metaphysical and scientific explanations may be unified in terms of general essences. Accordingly, essentialists may be better viewed as outlaws when it comes to laws of metaphysics. (shrink)

El presente artículo pretende mirar a Latinoamérica desde la perspectiva de la ontología. Y como hay algo que no acaba de encajar, busca en el inexplorado terreno de la meontología y el no-ser a partir de dos pensadores políticos latinoamericanos recientes, Dussel y Laclau. Por un lado, la Filosofía de la Liberación asocia el centro con la ontología y el ser, así como la periferia con lo Otro y el no-ser. De esto se desprende que, aun y asumiendo el heideggeriano (...) “olvido del ser”, la ontología helenocéntrica se basa en la negación aún más originaria y fundamental de la nada. A continuación, se intenta demostrar cómo esta renegación ha ido de la mano de la exclusión de lo bárbaro, lo popular y lo femenino, principalmente. Tras un breve ex cursus sobre Schmitt en tanto que la forma más acabada de horror vacui dentro de la ontología política europea, el artículo concluye con un análisis pormenorizado de la reconceptualización del vacío en la obra de Laclau, que puede permitir una mejor comprensión del populismo en general, y de su vertiente latinoamericana en particular. (shrink)

Vaccine research, as well as the development, testing, clinical trials, and commercial uses of vaccines involve complex processes with various biological data that include gene and protein expression, analysis of molecular and cellular interactions, study of tissue and whole body responses, and extensive epidemiological modeling. Although many data resources are available to meet different aspects of vaccine needs, it remains a challenge how we are to standardize vaccine annotation, integrate data about varied vaccine types and resources, and support advanced vaccine (...) data analysis and inference. To address these problems, the community-based Vaccine Ontology (VO) has been developed through collaboration with vaccine researchers and many national and international centers and programs, including the National Center for Biomedical Ontology (NCBO), the Infectious Disease Ontology (IDO) Initiative, and the Ontology for Biomedical Investigations (OBI). VO utilizes the Basic Formal Ontology (BFO) as the top ontology and the Relation Ontology (RO) for definition of term relationships. VO is represented in the Web Ontology Language (OWL) and edited using the Protégé-OWL. Currently VO contains more than 2000 terms and relationships. VO emphasizes on classification of vaccines and vaccine components, vaccine quality and phenotypes, and host immune response to vaccines. These reflect different aspects of vaccine composition and biology and can thus be used to model individual vaccines. More than 200 licensed vaccines and many vaccine candidates in research or clinical trials have been modeled in VO. VO is being used for vaccine literature mining through collaboration with the National Center for Integrative Biomedical Informatics (NCIBI). Multiple VO applications will be presented. (shrink)

The access-to-justice movement broadly concerns the extent to which people have the ability to resolve legally actionable problems. To the extent that individuals seek resolution through civil litigation, they can be disadvantaged by their unmet need for legal services, particularly in high-stakes cases and complicated areas of law. I propose an innovative legal intervention to this problem called “compensatory preliminary damages,” which builds from the work of Gideon Parchomovsky and Alex Stein. I argue that preliminary damages should function as (...) compensatory awards for harm to a plaintiff’s ability to access justice, rather than a contingency loan that might make indigent plaintiffs worse off than before if they lose. By awarding such damages, courts make plaintiffs whole for harm to their access to justice that is not conditional on a decision after the merits or their final recovery for the injuries alleged. As such, the award would not need to be repaid. -/- . (shrink)

The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated data is thereby of fundamental concern. Ontologies––structured, controlled, vocabularies––are designed to support consistency of interpretation, and thereby to prevent the development of data silos. This paper describes how ontologies are serving this purpose in the COVID-19 research domain, by following principles of the Open Biological and Biomedical Ontology (OBO) Foundry and by reusing existing ontologies such as the Infectious Disease Ontology (...) (IDO) Core, which provides terminological content common to investigations of all infectious diseases. We report here on the development of an IDO extension, the Virus Infectious Disease Ontology (VIDO), a reference ontology covering viral infectious diseases. We motivate term and definition choices, showcase reuse of terms from existing OBO ontologies, illustrate how ontological decisions were motivated by relevant life science research, and connect VIDO to the Coronavirus Infectious Disease Ontology (CIDO). We next use terms from these ontologies to annotate selections from life science research on SARS-CoV-2, highlighting how ontologies employing a common upper-level vocabulary may be seamlessly interwoven. Finally, we outline future work, including bacteria and fungus infectious disease reference ontologies currently under development, then cite uses of VIDO and CIDO in host-pathogen data analytics, electronic health record annotation, and ontology conflict-resolution projects. (shrink)

Platonism in the philosophy of mathematics is the doctrine that there are mathematical objects such as numbers. John Burgess and Gideon Rosen have argued that that there is no good epistemological argument against platonism. They propose a dilemma, claiming that epistemological arguments against platonism either rely on a dubious epistemology, or resemble a dubious sceptical argument concerning perceptual knowledge. Against Burgess and Rosen, I show that an epistemological anti- platonist argument proposed by Hartry Field avoids both horns of their (...) dilemma. (shrink)

El año 1962 vio la introducción, por parte de Kuhn y Feyerabend, de la tesis de la inconmensurabilidad de las teorías científicas . Desde entonces, la tesis ha sido debatida ampliamente y ha atraído muchos críticos. Su influencia aún es considerable, particularmente en las áreas de la historia y la filosofía de la ciencia interesadas en el cambio y la elección de teorías. Esta influencia se debe, en gran medida, a la inmensa popularidad de la obra maestra de Kuhn, La (...) Estructura de las revoluciones científicas, la cual asegura que la idea de la inconmensurabilidad continúe alcanzando un público amplio. Sin embargo, no es tan ampliamente apreciado que la versión de Kuhn de la inconmensurabilidad ha ido sufriendo, con el tiempo, un proceso continuo de revisión y clarificación. Como resultado de esto, la versión de la tesis por la que Kuhn es mejor conocido difiere notablemente de la versión que él asume en el presente. En este artículo presento un estudio del proceso de cambio, caracterizando las etapas principales por las que transcurre el concepto kuhniano de inconmensurabilidad. (shrink)

La revista Sophia se complace en presentar la publicación número 28 de su colección, en esta ocasión el núcleo de reflexión versa sobre: filosofía, tecnología e innovación en la educación. Los cambios propios de la era digital, así como los procesos de in-novación y los avances tecnocientíficos han ido configurado nuevas for-mas de ser, de pensar, de estar y de relacionarse con el mundo (Aguilar, 2011), por lo que hoy, más que nunca, es menester la reflexión sobre los fundamentos filosóficos (...) de la tecnología y las implicaciones que pueda tener en los diversos ámbitos del actuar humano, en especial en el ám-bito formativo. Es así que el tema del presente monográfico resulta de esencial interés en la construcción de una educación coherente, situada y propositiva, que impulse la actualización e innovación pedagógica y que responda a los desafíos de la realidad tecnológica y educativa actual. En este sentido, se plantean algunas interrogantes que direccionan las investigaciones del presente número, entre ellos sobresalen: ¿Cuáles han sido las consecuencias educativas de las implementaciones tecnológicas en el aula de clase?, ¿hacia qué tipo de educación nos puede llevar el progreso tecnológico sin límites?, ¿cuál es el nuevo rol del profesional de la educa-ción en la época de la innovación y los cambios tecnológicos acelerados?, ¿cuáles son los fundamentos filosóficos de la tecnología?, ¿cómo sustentar los procesos educativos en la conectividad y el pensamiento computacional sin restringir el desarrollo del pensamiento crítico y creativo del ser huma-no?, ¿puede la tecnología garantizar la excelencia educativa?, ¿cuáles son los aportes de la tecnología para mejorar el proceso de enseñanza-aprendizaje?, ¿cómo influyen los dispositivos tecnológicos en el desempeño académico y el desarrollo intelectual del estudiante?, ¿cuáles son los problemas y límites de la tecnología en la educación?, entre otras. Actualmente se ha convertido en condición necesaria vincular a la definición de 'tecnología' elementos relacionados con el internet y lo digital , sin embargo, la tekhné ha acompañado al hombre desde sus primeras herramientas usadas para la casa con las cuales comenzó a manipular la naturaleza de acuerdo a sus necesidades y posibilidades. (shrink)

According to commentators like Rosalind Krauss, Briony Fer, Caroline Jones, and Michael Fried, Clement Greenberg’s formalist/positivist device of “medium-specificity” debars errant affective aesthetic experiences that are embodied; despite significant differences in how these theorists arrive at this conclusion, one shared point of emphasis is Greenberg’s inheriting Kant’s disinterested conception of pleasure in reflective judgments of beauty. Offering a textualist review of Kant’s Analytic of the Beautiful, I seek to demonstrate that neither Greenberg, nor Greenberg’s critics, are correct in their account (...) of Kant’s judgments of beauty.1 Specifically, I argue that Greenberg conflates Kant’s conception of judgments of free beauty (pulchritudo vaga) with merely adherent beauty (pulchritudo adhaerens). In formulating a rejoinder to Greenberg and the misplacement of Greenberg as a Kantian, and following Diarmuid Costello, I hope to save a path for a Kantian aesthetics of the present, much in the spirit of other broadly Kantian art historians and philosophers of art/aesthetics (e.g., Thierry de Duve, Paul Guyer, Ido Geiger, etc.). (shrink)

The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Ontologies – structured, controlled, vocabularies – are designed to support consistency of interpretation, and thereby to prevent the development of data silos. This paper describes how ontologies are serving this purpose in the virus research domain, following the principles of the Open Biological and Biomedical Ontology (OBO) Foundry and drawing on the resources of the Infectious Disease Ontology (IDO) Core. We report the development of the Virus Infectious (...) Disease Ontology (VIDO), a reference ontology extending IDO Core covering viral infectious diseases. We examine newly minted terms, showcase ontology term reuse, and illustrate the use of VIDO by annotating selections from recent life science research on SAR-CoV-2, in the interest of supporting machine learning projects. (shrink)

Many philosophers of mathematics are attracted by nominalism – the doctrine that there are no sets, numbers, functions, or other mathematical objects. John Burgess and Gideon Rosen have put forward an intriguing argument against nominalism, based on the thought that philosophy cannot overrule internal mathematical and scientific standards of acceptability. I argue that Burgess and Rosen’s argument fails because it relies on a mistaken view of what the standards of mathematics require.

Esta obra compila los estudios presentados en las I Jornadas de Filosofía del Instituto CEU de Humanidades Ángel Ayala y está prologada por Abelardo Lobato, O. P. Los filósofos tienen el deber de buscar y alcanzar la verdad apelando a las fuerzas de la razón, la cual, por cierto, no impide otras vías genuinas de conocimiento, como la fe. La búsqueda intelectual exige un trabajo de análisis que debe afinarse ante las obcecaciones que a menudo se interponen en el horizonte (...) de la existencia humana. En no pocos momentos de la historia ha habido claudicaciones generalizadas ante esa búsqueda, olvidos más o menos conscientes de que las verdades se alcanzan si se mantiene la esperanza de sabiduría y el amor a ella. El relativismo y el escepticismo se presentan casi como el polo opuesto de esa esperanza y ese amor; como una consecuencia de la “con-fusión” cultural, de las mentiras interesadas y de la desidia moral de algunas sociedades. La nuestra, la europea occidental, es una de ellas. El relativismo afecta al modo de pensar y de comportarse del hombre y es habitual que le lleve por vericuetos que a la postre terminan dañándole a él y a sus congéneres. En este libro se analizan algunos errores que han llevado a suscribir las tesis del relativismo y a rechazar la posibilidad de dar con algunas verdades comunes para todos. La obra tiene dos partes, una histórica y otra temática. Las páginas con enfoque histórico estudian las tesis que sobre el relativismo han mantenido algunos pensadores o corrientes de la filosofía. De su lectura se puede extraer la conclusión de que el fenómeno del relativismo es tan viejo y tan actual como el propio hombre y su apertura inteligente a la verdad. Filósofos de la época antigua de la talla de Protágoras, Pirrón o los “Académicos” coetáneos de San Agustín; modernos como Descartes; contemporáneos como Wittgenstein o Kuhn han dejado huellas que luego abrieron el camino hacia un régimen de pensamiento en que el hombre abandona la posibilidad de admitir verdades universales. Algunos argumentos favorables al relativismo —y, más aún, algunas actitudes “propedéuticas” de él— se han ido instalando culturalmente hasta consolidarse de manera cada vez más indiscutida. La segunda parte analiza el relativismo de forma temática, como un asunto abordable desde las diversas ramas del saber filosófico. Así, se tratan las repercusiones que tiene esta forma de pensamiento en la pragmática, la lógica, la estética o la religión, y se intentan desenmascarar los tópicos y falsos argumentos que justifican un comportamiento ético o religioso “abierto a todas las opciones”. (shrink)

Review of two recent works on J.G.H. Feder: -/- Johann Georg Heinrich Feder. Ausgewählte Schriften. Hrgb. Von Hans-Peter Nowitzki, Udo Roth, Gideon Stiening. Berlin/Boston: De Gruyter, 2018. Werkprofile Band 9. -/- and -/- Johann Georg Heinrich Feder (1740-1821): Empirismus und Popularphilosophie Zwischen Wolff und Kant. Hrgb. Von Hans-Peter Nowitzki, Udo Roth, Gideon Stiening. Berlin/Boston: De Gruyter, 2018. Werkprofile Band 10.

[English] This paper aims to discuss ten traditional and contemporary methodological paradigms in African philosophy, and demonstrates how they may apply to African environmental ethics research. The methods include: Ethno-philosophy, Sage Philosophy, Conversational Philosophy, Conceptual Mandelanization, Eco-Afrocentricism, Indigenous Language Analysis, Eco-Afro-feminism, Conceptual Decolonization, Storytelling Philosophy, and Cultural Adaptationism. The significance and limitations of the methodologies are highlighted. The concept and principles of African environmental ethics are analyzed and discussed to facilitate an understanding of the conceptual frameworks that underpin the methodologies. (...) In conclusion, the discourse demonstrates that environmental ethics research in Africa should be based on African philosophical methodologies so as to facilitate production of research that will be relevant in African contexts. -/- [Annang] N̄wed nduongo ami ayem ibene nwọ́d mme n̄kaan nne mfa usung unam nduongo ke vilọsọvi Afrịke , nne nte amọ ekeme iwam unam nduongo mbanga ido ukpeme nkan-nkuk ke Afrịke. Mme usung unam nduongo ami nsehe ade ami: vilọsọvi mben ufọk, vilọsọvi n̄kan ideen, vilọsọvi nneme, vilọsọvi Mandela, “Eco-Afrocentricism”, nduongore usem utiit ajid, vilọsọvi ibaan Afrịke, vilọsọvi mkpọk-nyak, vilọsọvi n̄ke, nne ukpep ido idung agwo. N̄wed ami abene awọd mme ikek nne nde mem idem usung nduongo ami. N̄wed ami atang mkpọ abanga se ido ukpeme nkan-nkuk ke Afrịke anwongo nne mme itai amọ, nne nte amọ ewam mbon nduongo ediọhọ nnanga ekpekakpa ibọrọ nduongo amọ. Ke n̄suuk ikọ, ukpep ami mkpọ abene awọd ate ke ekpena ekama usung nduongo vilọsọvi Afrịke enam nduongo ebanga ido ukpeme nkan-nkuk ke Afrịke man ibọrọ nduongo asanga akekem nne se adiiwam Afrịke. (shrink)

Esta investigación se emprende motivada por la necesidad de desentrañar la progresión de los modelos de aprendizaje, los cuales se han ido adaptando para responder a las demandas de la sociedad en su dinámica constante de fluctuación y transformaciones. El objetivo de este trabajo es examinar de forma sistemática la evolución de los modelos de aprendizaje, destacando los cambios paradigmáticos que han favorecido la transición de enfoques de aprendizaje tradicionales hacia propuestas más innovadoras y transdisciplinarias. Para lograrlo, se lleva a (...) cabo un análisis bibliográfico apoyado en el método hermenéutico para la interpretación contextual de la literatura y los discursos, a fin de desentrañar las complejidades inherentes en la evolución de los modelos de aprendizaje. Los resultados resaltan la influencia limitante del paradigma de la simplicidad en la formación educativa tradicional y la necesidad de un giro hacia la dialogicidad y la colaboración e integración disciplinaria para avanzar hacia la complejidad. Se concluye argumentando a favor de la adopción del paradigma de la complejidad, abogando por una epistemología transdisciplinariay un enfoque de aprendizaje interestructurante, que permitan el desarrollo humano integral.El reconocimiento de la complejidad humana en la enseñanza y el aprendizaje exige una transformación radical de la educación hacia prácticas más holísticas y transformadoras, esenciales para construir una sociedad equitativa y justa. (shrink)

What do we do with Judges? This two-edged word? This ambidextrous book? These ambivalent heroes? The Judges were drawing their last fleeting breaths shipwrecked and scattered upon the shores of historical-critical-grammatical-linear-modernist-masculine interpretation. "The narrative is primitive," they said. "The editors have made a mess," they exclaimed. "The conclusion is really an appendix," another said. Then the bible-acrobats jumped in pretending there was no literary carnage while at the same time drawing our eyes away from the literary carnage. "No, no, there (...) is an order to this disorderly book!" "Gideon is a man of faith," they explained. "Gideon is a sham," others retorted. "Long live the king," they cried. "Oh no, the king will bring down the nation," others said. Enter the latest literary critics and the fresh feminist readers to save the day. And save they have. Barry noted the irony. Cheryl called attention to the elaborate, spiraling labyrinth. Phyllis remembered the forgotten. Mieke heralded the incoherence. Deborah the Bee slings Barak with irony. Cowardly Jephthah sacrifices his virgin daughter immediately after he is filled with the spirit. Blind Samson remains stuck in some adolescent, Pinnochio-like stage milling around the same old vices. The Levite, the man of word and sacrifice, lies to the people and dismembers his wife. To beat it all the myopic narrator joins in lock step with the other blind characters stumbling around in the narrative. What manner of text is this? These Judges, these stories, are even more troubling now that we take them seriously. Now what do we do with Judges? The recent scholarship is most promising, but I think we must press forward, or is that backward, or perhaps to another plan. Perhaps Judges hearkens forward to the postmodern. What would Judges look like if we viewed the story through a postmodern lens? Would we see the text in another dimension? Would we let the characters live and breathe as confusing, confounding, intricate characters? Judges speaks to me. These judges, they teach me. How can I ever forget my reading of Judges? For once I found a text reflecting the madness of faith in my maddening world. For once I saw a text like Pablo. I heard the echo of Umberto. I noted the faint murmurings of Jacques. I danced a most joyous jig with Julia. I saw, up ahead, or was that behind me, or over to the side, Martin's flickering candle. Mieke, meet Jael. Barak, meet Barry. Jacques, meet Gideon. Samson, meet Martin. Umberto, meet the narrator or two or three. Pablo, meet the Levite's wife---sorry, she has no name. (shrink)

Estados Unidos y el mundo están en el proceso de colapso de un crecimiento excesivo de la población, la mayoría de ella para el siglo pasado, y ahora todo ello, debido a la 3ª gente del mundo. El consumo de recursos y la adición de 4 mil millones más CA. 2100 colapsarán la civilización industrial y traerán hambre, enfermedad, violencia y guerra a una escala asombrosa. La tierra pierde al menos el 1% de su suelo vegetal cada año, por lo (...) que se acerca a 2100, la mayor parte de su capacidad de cultivo de alimentos se habrá ido. Miles de millones morirán y la guerra nuclear es segura. En Estados Unidos, esto está siendo enormemente acelerado por la inmigración masiva y la reproducción de inmigrantes, combinada con los abusos hechos posible por la democracia. La naturaleza humana depravada convierte inexorablemente el sueño de la democracia y la diversidad en una pesadilla de delincuencia y pobreza. China seguirá abrumar a América y al mundo, siempre y cuando mantenga la dictadura que limita el egoísmo. La causa raíz del colapso es la incapacidad de nuestra psicología innata para adaptarse al mundo moderno, lo que lleva a las personas a tratar a las personas no relacionadas como si tuvieran intereses comunes. La idea de los derechos humanos es una fantasía malvada promovida por los izquierdistas para atraer la atención de la destrucción despiadada de la tierra por una maternidad sin restricciones del tercer mundo. Esto, además de la ignorancia de la biología básica y la psicología, conduce a los delirios de ingeniería social de los parcialmente educados que controlan las sociedades democráticas. Pocos entienden que si usted ayuda a una persona a lastimar a alguien más, no hay almuerzo gratis y cada artículo que alguien consume destruye la tierra más allá de la reparación. En consecuencia, las políticas sociales en todas partes son insostenibles y, una por una, todas las sociedades sin estrictos controles sobre el egoísmo se derrumbarán en la anarquía o la dictadura. Los hechos más básicos, casi nunca mencionados, son que no hay suficientes recursos en Estados Unidos o en el mundo para levantar un porcentaje significativo de los pobres de la pobreza y mantenerlos allí. El intento de hacer esto es la quiebra de Estados Unidos y la destrucción del mundo. La capacidad de la tierra para producir alimentos disminuye diariamente, al igual que nuestra calidad genética. Y ahora, como siempre, de lejos el mayor enemigo de los pobres es el de otros pobres y no los ricos. Sin cambios dramáticos e inmediatos, no hay esperanzas de evitar el colapso de América, o cualquier país que siga un sistema democrático. (shrink)

[English] The paper observed that the various ethics that constitute the system of African environmental ethics are not based on or linked to any known African ontology and formal logic. It argued that the contextualisation of African environmental ethics on African ontology and African logic is essential since Western ontology and logic do not serve to adequately explain and provide proper meanings to the various concepts and propositions employed in the African environmental ethics. Therefore, the paper aimed to, and indeed, (...) link and establishes African environmental ethics on a definite and sound African ontology and formal logic based on Ibuanyidanda complementary ontology and Ezumezu integrativist logic. -/- [Annang] Nwed ndun̄ọ ami akondo ada akud ate k’ idem mme ido ukpeme nkan-n̄kuk ke Africa ada nsan nsan ye ọntọlọgy ye lọgik Africa. Nnwed ami abenne awọ́d ate ke ọntọlọgy ye lọgik mfia agwo iwamma ke adinam awan̄a mme nsio nsio akpọ-ikọ, adaha ikọ, mme usem, ye mme edu ake 'adọhọke ke mme ido ukpeme nkan-n̄kuk ke Africa. Ntak ade anam ukpep mkpọ ami anwana ndiben ido ukpeme nkan-n̄kuk Africa n̄ka n̄ke kọọn̄ ke ọntọlọgy ye lọgik afọnnọ nte itiat ikaba, ade anam anye asan̄a 'ke kem ye Ibuanyidanda Ontology ye Ezumezu Logic. (shrink)