Results for 'James Lock'

972 found
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  1. Impact of COVID-19 on liver transplantation in Hong Kong and Singapore: A modelling study.Eunice Tan, Wei Liang Quek, Haroun Chahed, Shridhar Ganpathi Iyer, Prema Raj Jeyaraj, Guan-Huei Lee, Albert Chan, Stephanie Cheng, Jan Hoe, Ek Khoon Tan, Lock Yue Chew, James Fung, Melvin Chen, Mark Muthiah & Daniel Huang - 2021 - The Lancet Regional Health-Western Pacific 16:100262.
    Liver transplantation (LT) activities during the COVID-19 pandemic have been curtailed in many countries. The impact of various policies restricting LT on outcomes of potential LT candidates is unclear. We studied all patients on the nationwide LT waitlists in Hong Kong and Singapore between January 2016 and May 2020. We used continuous time Markov chains to model the effects of different scenarios and varying durations of disruption on LT candidates.
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  2. Deep Epistemic Vices.Ian James Kidd - 2018 - Journal of Philosophical Research 43:43-67..
    Although the discipline of vice epistemology is only a decade old, the broader project of studying epistemic vices and failings is much older. This paper argues that contemporary vice epistemologists ought to engage more closely with these earlier projects. After sketching some general arguments in section one, I then turn to deep epistemic vices: ones whose identity and intelligibility depends on some underlying conception of human nature or the nature of reality. The final section then offers a case study from (...)
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  3. The Rhetoric of Berkeley's Philosophy. [REVIEW]James Mahon - 1996 - Berkeley Newsletter 14:15-17.
    In this review of Peter Walmsley's book, the first book-length treatment of Berkeley as a writer, Berkeley is shown to be a master stylist. He is also shown to have a theory of language that is "explicitly rhetorical," since he held, contrary to Locke, that language had ends other than the communication of ideas.
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  4. The Perfectly True Knowledge.James Theophilus Edwards - forthcoming - None.
    My paper discusses the philosophical interrelationship between perfection, truth, and knowledge. The connection that exists between these three concepts underscores the argument of my paper that they are all one and the same thing. -/- The concepts of perfection, truth and knowledge are analysed in that order. I analyse perfection and demonstrate the practicalities of my arguments. Truth is then scrutinized and defined to illustrate its intimate relationship with perfection leading to the conclusion that knowledge being ‘truth that is perfect’. (...)
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  5. Language and Emotional Knowledge: A Case Study on Ability and Disability in Williams Syndrome.Christine A. James - 2009 - Biosemiotics 2 (2):151-167.
    Williams Syndrome provides a striking test case for discourses on disability, because the characteristics associated with Williams Syndrome involve a combination of “abilities” and “disabilities”. For example, Williams Syndrome is associated with disabilities in mathematics and spatial cognition. However, Williams Syndrome individuals also tend to have a unique strength in their expressive language skills, and are socially outgoing and unselfconscious when meeting new people. Children with Williams are said to be typically unafraid of strangers and show a greater interest in (...)
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  6. Rights and Reason: An Introduction to the Philosophy of Rights. [REVIEW]James Mahon - 2005 - International Journal of Philosophical Studies 13:285-289.
    In this review I consider Gorman's arguments for redescrbiing the history of ethics, from Plato to Isaiah Berlin, as the history of theories of human rights, and for the conclusions that human rights are dependent, that they change over time, and that they may conflict with each other. I disagree with his interpretations of Plato, Hobbes, and Kant, as well as the idea that their moral theories can be converted into theories of human rights without loss, and I argue that (...)
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  7. James Africanus Beale Horton: Racism and the Fate of Naturalism in Victorian Philosophical Anthropology. [REVIEW]Zeyad El Nabolsy - 2023 - Black Issues in Philosophy/ Blog of the Apa.
    There has been a recent increase in interest in the place of race in the writings of modern canonical European philosophers (e.g., in Locke, Hume, Kant, and Hegel). However, while it is undoubtedly necessary to undertake such investigations, we should also not stop there, insofar as stopping there does not, in fact, overturn the charge of Eurocentrism or parochialism which has often been leveled against academic philosophy. Because the circle of interlocutors is not being expanded in such an approach, it (...)
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  8. Logical Normativity and Rational Agency—Reassessing Locke's Relation to Logic.Huaping Lu-Adler - 2018 - Journal of the History of Philosophy 56 (1):75-99.
    There is an exegetical quandary when it comes to interpreting Locke's relation to logic.On the one hand, over the last few decades a substantive amount of literature has been dedicated to explaining Locke's crucial role in the development of a new logic in the seventeenth and eighteenth centuries. John Yolton names this new logic the "logic of ideas," while James Buickerood calls it "facultative logic."1 Either way, Locke's Essay is supposedly its "most outspoken specimen" or "culmination."2 Call this reading (...)
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  9. The Development of the ‘Specious Present’ and James’ Views on Temporal Experience.Holly Andersen - 2014 - In Dan Lloyd Valtteri Arstila (ed.), Subjective Time: The Philosophy, Psychology, and Neuroscience of Temporality. Cambridge, MA: Mit Press. pp. 25-42.
    This chapter examines the philosophical discussion concerning the relationship between time, memory, attention, and consciousness, from Locke through the Scottish Common Sense tradition, in terms of its influence on James' development of the specious present doctrine. The specious present doctrine is the view that the present moment in experience is non punctate, but instead comprises some nonzero amount of time; it contrasts with the mathematical view of the present, in which the divide between past and future is merely a (...)
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  10. The rise of empiricism: William James, Thomas hill green, and the struggle over psychology.Alexander Klein - 2007 - Dissertation, Indiana University, Bloomington
    The concept of empiricism evokes both a historical tradition and a set of philosophical theses. The theses are usually understood to have been developed by Locke, Berkeley, and Hume. But these figures did not use the term “empiricism,” and they did not see themselves as united by a shared epistemology into one school of thought. My dissertation analyzes the debate that elevated the concept of empiricism (and of an empiricist tradition) to prominence in English-language philosophy. -/- In the 1870s and (...)
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  11. The Philosophical Landscape on Attention.Carolyn Dicey Jennings - 2020 - In The Attending Mind. New York: Cambridge University Press.
    Attention has a long history in philosophy, despite its near absence in the twentieth century. This chapter provides an overview of philosophical research on attention. It begins by explaining the concept of "selection from limitation," contrasting it with the more recent "selection for action." It reviews historical texts that discuss attention, focusing on those in the Western canon whose understanding of "attention" aligns with contemporary usage. It then describes the differential treatment of attention in phenomenology and behaviorism in the last (...)
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  12. The contribution of prefrontal executive processes to creating a sense of self.William Hirstein - 2011 - Mens Sana Monographs 9 (1):150-158.
    According to several current theories, executive processes help achieve various mental actions such as remembering, planning and decision-making, by executing cognitive operations on representations held in consciousness. I plan to argue that these executive processes are partly responsible for our sense of self, because of the way they produce the impression of an active, controlling presence in consciousness. If we examine what philosophers have said about the "ego" (Descartes), "the Self" (Locke and Hume), the "self of all selves" (William (...)), we will find that it fits what is now known about executive processes. Hume, for instance, famously argued that he could not detect the self in consciousness, and this would correspond to the claim (made by Crick and Koch, for instance) that we are not conscious of the executive processes themselves, but rather of their results. (shrink)
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  13.  44
    Reclaiming Democratic Classical Liberalism.David Ellerman - 2020 - In D. Hardwick & L. Marsh (eds.), Reclaiming Liberalism. Palgrave Studies in Classical Liberalism. pp. 1-39.
    This essay shows that the principles of classical liberalism (e.g., James Buchanan) do not apply to the firm based on the employer-employee relationship. However, there is a deeper democratic classical liberalism tradition based on inalienable rights, but it rules out the employment or human rental relation.
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  14. The Understanding.John P. Wright - 2013 - In James Anthony Harris (ed.), The Oxford Handbook of British Philosophy in the Eighteenth Century. Oxford, England: Oxford University Press UK. pp. 148-70.
    The article discusses the varying conceptions of the faculty of ‘the understanding’ in 18th-century British philosophy and logic. Topics include the distinction between the understanding and the will, the traditional division of three acts of understanding and its critics, the naturalizing of human understanding, conceiving of the limits of human understanding, British innatism and the critique of empiricist conceptions of the understanding, and reconceiving the understanding and the elimination of scepticism. Authors discussed include Richard Price, James Harris, Zachary Mayne, (...)
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  15. Fanaticism and the History of Philosophy.Paul Katsafanas (ed.) - 2023 - London: Rewriting the History of Philosophy.
    Voltaire called fanaticism the "monster that pretends to be the child of religion". Philosophers, politicians, and cultural critics have decried fanaticism and attempted to define the distinctive qualities of the fanatic, whom Winston Churchill described as "someone who can't change his mind and won't change the subject". Yet despite fanaticism's role in the long history of social discord, human conflict, and political violence, it remains a relatively neglected topic in the history of philosophy. In this outstanding inquiry into the philosophical (...)
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  16. Plato's Theory of Forms and Other Papers.John-Michael Kuczynski - 2020 - Madison, WI, USA: College Papers Plus.
    Easy to understand philosophy papers in all areas. Table of contents: Three Short Philosophy Papers on Human Freedom The Paradox of Religions Institutions Different Perspectives on Religious Belief: O’Reilly v. Dawkins. v. James v. Clifford Schopenhauer on Suicide Schopenhauer’s Fractal Conception of Reality Theodore Roszak’s Views on Bicameral Consciousness Philosophy Exam Questions and Answers Locke, Aristotle and Kant on Virtue Logic Lecture for Erika Kant’s Ethics Van Cleve on Epistemic Circularity Plato’s Theory of Forms Can we trust our senses? (...)
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  17. Assessing the Wellbeing Impacts of the COVID-19 Pandemic and Three Policy Types: Suppression, Control, and Uncontrolled Spread.Matthew D. Adler, Richard Bradley, Maddalena Ferranna, Marc Fleurbaey, James Hammitt & Alex Voorhoeve - 2020 - Thinktank 20 Policy Briefs for the G20 Meeting in Saudi Arabia 2020.
    The COVID-19 crisis has forced a difficult trade-off between limiting the health impacts of the virus and maintaining economic activity. Welfare economics offers tools to conceptualize this trade-off so that policy-makers and the public can see clearly what is at stake. We review four such tools: the Value of Statistical Life (VSL); the Value of Statistical Life Years (VSLYs); Quality-Adjusted Life-Years (QALYs); and social welfare analysis, and argue that the latter are superior. We also discuss how to choose policies that (...)
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  18. Panorama Histórico dos Problemas Filosóficos.Emanuel Isaque Cordeiro da Silva - manuscript
    Antes de entrar cuidadosamente no estudo de cada filósofo, em suas respectivas ordens cronológicas, é necessário dar um panorama geral sobre eles, permitindo, de relance, a localização deles em tempos históricos e a associação de seus nomes com sua teoria ou tema central. l. OS FILÓSOFOS PRÉ-SOCRÁTICOS - No sétimo século antes de Jesus Cristo, nasce o primeiro filósofo grego: Tales de Mileto2 . Ele e os seguintes filósofos jônicos (Anaximandro: Ἀναξίμανδρος: 3 610-546 a.C.) e Anaxímenes: (Άναξιμένης: 586-524 a.C.) tentaram (...)
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  19. How to Balance Lives and Livelihoods in a Pandemic.Matthew D. Adler, Richard Bradley, Marc Fleurbaey, Maddalena Ferranna, James Hammitt, Remi Turquier & Alex Voorhoeve - 2023 - In Julian Savulescu & Dominic Wilkinson (eds.), Pandemic Ethics: From Covid-19 to Disease X. Oxford University Press. pp. 189-209.
    Control measures, such as “lockdowns”, have been widely used to suppress the COVID-19 pandemic. Under some conditions, they prevent illness and save lives. But they also exact an economic toll. How should we balance the impact of such policies on individual lives and livelihoods (and other dimensions of concern) to determine which is best? A widely used method of policy evaluation, benefit–cost analysis (BCA), answers these questions by converting all the effects of a policy into monetary equivalents and then summing (...)
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  20. Lockean and Cultural Property concepts of property do not oblige museums to repatriation artefacts: A critique of using Property Claims to defend Repatriation.Esha Dev - 2023 - Dissertation, Nottingham University
    This dissertation asks the question of how ownership over property in museums is decided. It concludes that for a range of candidate concepts of property, none of them oblige museums to repatriate artefacts unless we weaken Young’s theory to repatriate through how much artefacts are valued by a culture. However, this dissertation rejects the Ownership Argument as a defence for repatriation. To do this, it will be considering three options of how we understand ‘property’ through three scholars: Locke, Young and (...)
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  21. Third‐person knowledge ascriptions: A crucial experiment for contextualism.Jumbly Grindrod, James Andow & Nat Hansen - 2017 - Mind and Language (2):1-25.
    In the past few years there has been a turn towards evaluating the empirical foundation of epistemic contextualism using formal (rather than armchair) experimental methods. By-and-large, the results of these experiments have not supported the original motivation for epistemic contextualism. That is partly because experiments have only uncovered effects of changing context on knowledge ascriptions in limited experimental circumstances (when contrast is present, for example), and partly because existing experiments have not been designed to distinguish between contextualism and one of (...)
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  22. Why are people so darn past biased?Preston Greene, Andrew James Latham, Kristie Miller & James Norton - 2022 - In Christoph Hoerl, Teresa McCormack & Alison Fernandes (eds.), Temporal Asymmetries in Philosophy and Psychology. Oxford: Oxford University Press. pp. 139-154.
    Many philosophers have assumed that our preferences regarding hedonic events exhibit a bias toward the future: we prefer positive experiences to be in our future and negative experiences to be in our past. Recent experimental work by Greene et al. (ms) confirmed this assumption. However, they noted a potential for some participants to respond in a deviant manner, and hence for their methodology to underestimate the percentage of people who are time neutral, and overestimate the percentage who are future biased. (...)
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  23. Aristotle on the Unity of the Nutritive and Reproductive Functions.Cameron F. Coates & James G. Lennox - 2020 - Phronesis 65 (4):414-466.
    In De Anima 2.4, Aristotle claims that nutritive soul encompasses two distinct biological functions: nutrition and reproduction. We challenge a pervasive interpretation which posits ‘nutrients’ as the correlative object of the nutritive capacity. Instead, the shared object of nutrition and reproduction is that which is nourished and reproduced: the ensouled body, qua ensouled. Both functions aim at preserving this object, and thus at preserving the form, life, and being of the individual organism. In each case, we show how Aristotle’s detailed (...)
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  24. The Story About Propositions.Bradley Armour-Garb & James A. Woodbridge - 2010 - Noûs 46 (4):635-674.
    It is our contention that an ontological commitment to propositions faces a number of problems; so many, in fact, that an attitude of realism towards propositions—understood the usual “platonistic” way, as a kind of mind- and language-independent abstract entity—is ultimately untenable. The particular worries about propositions that marshal parallel problems that Paul Benacerraf has raised for mathematical platonists. At the same time, the utility of “proposition-talk”—indeed, the apparent linguistic commitment evident in our use of 'that'-clauses (in offering explanations and making (...)
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  25. Randomness and the justification of induction.Scott Campbell & James Franklin - 2004 - Synthese 138 (1):79 - 99.
    In 1947 Donald Cary Williams claimed in The Ground of Induction to have solved the Humean problem of induction, by means of an adaptation of reasoning first advanced by Bernoulli in 1713. Later on David Stove defended and improved upon Williams’ argument in The Rational- ity of Induction (1986). We call this proposed solution of induction the ‘Williams-Stove sampling thesis’. There has been no lack of objections raised to the sampling thesis, and it has not been widely accepted. In our (...)
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  26. Dejustifying Scientific Progress.Finnur Dellsén & James Norton - forthcoming - Philosophy of Science.
    Stegenga (forthcoming) formulates and defends a novel account of scientific progress, according to which science makes progress just in case there is a change in scientific justification. Here we present several problems for Stegenga’s account, concerning respectively (i) obtaining misleading evidence, (ii) losses or destruction of evidence, (iii) oscillations in scientific justification, and (iv) the possibility of scientific regress. We conclude by sketching a substantially different justification-based account of scientific progress that avoids these problems.
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  27. When is deception in research ethical?Nafsika Athanassoulis & James Wilson - 2009 - Clinical Ethics 4 (1):44-49.
    This article examines when deceptive withholding of information is ethically acceptable in research. The first half analyses the concept of deception. We argue that there are two types of accounts of deception: normative and non-normative, and argue that non-normative accounts are preferable. The second half of the article argues that the relevant ethical question which ethics committees should focus on is not whether the person from whom the information is withheld will be deceived, but rather on the reasonableness of withholding (...)
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  28. The Ethics of Automating Therapy.Jake Burley, James J. Hughes, Alec Stubbs & Nir Eisikovits - 2024 - Ieet White Papers.
    The mental health crisis and loneliness epidemic have sparked a growing interest in leveraging artificial intelligence (AI) and chatbots as a potential solution. This report examines the benefits and risks of incorporating chatbots in mental health treatment. AI is used for mental health diagnosis and treatment decision-making and to train therapists on virtual patients. Chatbots are employed as always-available intermediaries with therapists, flagging symptoms for human intervention. But chatbots are also sold as stand-alone virtual therapists or as friends and lovers. (...)
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  29. Singular Thought and Mental Files: An Introduction.Rachel Goodman & James Genone - 2020 - In Rachel Goodman, James Genone & Nick Kroll (eds.), Singular Thought and Mental Files. New York, NY, United States of America: Oxford University Press. pp. 1-17.
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  30. A Case for Machine Ethics in Modeling Human-Level Intelligent Agents.Robert James M. Boyles - 2018 - Kritike 12 (1):182–200.
    This paper focuses on the research field of machine ethics and how it relates to a technological singularity—a hypothesized, futuristic event where artificial machines will have greater-than-human-level intelligence. One problem related to the singularity centers on the issue of whether human values and norms would survive such an event. To somehow ensure this, a number of artificial intelligence researchers have opted to focus on the development of artificial moral agents, which refers to machines capable of moral reasoning, judgment, and decision-making. (...)
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  31. Psychological underpinnings of philosophy.Steven James Bartlett - 1989 - Metaphilosophy 20 (3-4):295-305.
    A description of the psychological profile of the philosophical personality. ●●●●● -/- 2022 UPDATE: The approach of this paper has been updated and developed further in Chapters 1 and 2 of the author’s 2021 book _Critique of Impure Reason: Horizons of Possibility and Meaning_. The book is available both in a printed edition (under ISBN 978-0-578-88646-6 from Barnes & Noble, Amazon, and other booksellers) and an Open Access eBook edition (available through Philpapers under the book’s title and other philosophy online (...)
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  32. God and the brain: the rationality of belief -- free download of entire book!Kelly James Clark - 2019 - Grand Rapids, Michigan: William B. Eerdmans Publishing Company.
    Disproof of heaven? -- Brain and gods -- The rational stance -- Reason and belief in God -- Against naturalism -- Atheism, inference, and IQ -- Atheism, autism, and intellectual humility -- Googling God -- Inference, intuition, and rationality.
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  33. Reason, Metaphysics, and Mind: New Essays on the Philosophy of Alvin Plantinga.Kelly James Clark & Michael Reason Rea (eds.) - 2012 - , US: Oup Usa.
    In May 2010, philosophers, family and friends gathered at the University of Notre Dame to celebrate the career and retirement of Alvin Plantinga, widely recognized as one of the world's leading figures in metaphysics, epistemology, and the philosophy of religion. Plantinga has earned particular respect within the community of Christian philosophers for the pivotal role that he played in the recent renewal and development of philosophy of religion and philosophical theology. Each of the essays in this volume engages with some (...)
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  34. Confused Terms in Ordinary Language.Greg Frost-Arnold & James R. Beebe - 2020 - Journal of Logic, Language and Information 29 (2):197-219.
    Confused terms appear to signify more than one entity. Carnap maintained that any putative name that is associated with more than one object in a relevant universe of discourse fails to be a genuine name. Although many philosophers have agreed with Carnap, they have not always agreed among themselves about the truth-values of atomic sentences containing such terms. Some hold that such atomic sentences are always false, and others claim they are always truth-valueless. Field maintained that confused terms can still (...)
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  35. I Own therefore I Am. The Ontology of Property.Marina Christodoulou - 2021 - In Mariano L. Bianca & Paolo Piccari (eds.), Why Does What Exists Exist? Some Hypotheses on the Ultimate “Why” Question. Cambridge Scholars Publishing. pp. 169-182.
    Citation: Marina Christodoulou, “I Own therefore I Am. The Ontology of Property”, In Why Does What Exists Exist? Some Hypotheses on the Ultimate “Why” Question, edited by Mariano L. Bianca,Paolo Piccari. Cambridge Scholars Publishing, 2021, pp. 169-182. Contributors: Mariano L. Bianca, Konstantinos Boultzis, Marina Christodoulou, Maurizio Ferraris, Marco G. Giammarchi, Enrico Guglielminetti, Roberta Lanfredini, Fabio Minazzi, Crister Nyberg, Paolo Piccari, Paolo Rossi. ISBN (10): 1-5275-6294-8; ISBN (13): 978-1-5275-6294-3 -/- -------------- -/- The concept of Property is what attaches us to Existence, (...)
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  36. Launching of Davydov solitons in protein α-helix spines.Danko D. Georgiev & James F. Glazebrook - 2020 - Physica E: Low-Dimensional Systems and Nanostructures 124:114332.
    Biological order provided by α-helical secondary protein structures is an important resource exploitable by living organisms for increasing the efficiency of energy transport. In particular, self-trapping of amide I energy quanta by the induced phonon deformation of the hydrogen-bonded lattice of peptide groups is capable of generating either pinned or moving solitary waves following the Davydov quasiparticle/soliton model. The effect of applied in-phase Gaussian pulses of amide I energy, however, was found to be strongly dependent on the site of application. (...)
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  37. Quantum transport and utilization of free energy in protein α-helices.Danko D. Georgiev & James F. Glazebrook - 2020 - Advances in Quantum Chemistry 82:253-300.
    The essential biological processes that sustain life are catalyzed by protein nano-engines, which maintain living systems in far-from-equilibrium ordered states. To investigate energetic processes in proteins, we have analyzed the system of generalized Davydov equations that govern the quantum dynamics of multiple amide I exciton quanta propagating along the hydrogen-bonded peptide groups in α-helices. Computational simulations have confirmed the generation of moving Davydov solitons by applied pulses of amide I energy for protein α-helices of varying length. The stability and mobility (...)
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  38. Is there a case for ad hominem arguments?Gary James Jason - 1984 - Australasian Journal of Philosophy 62 (2):182 – 185.
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  39. Punishment and psychopathy: a case-control functional MRI investigation of reinforcement learning in violent antisocial personality disordered men.Sarah Gregory, R. James Blair, Dominic Ffytche, Andrew Simmons, Veena Kumari, Sheilagh Hodgins & Nigel Blackwood - 2014 - Lancet Psychiatry 2:153–160.
    Background Men with antisocial personality disorder show lifelong abnormalities in adaptive decision making guided by the weighing up of reward and punishment information. Among men with antisocial personality disorder, modifi cation of the behaviour of those with additional diagnoses of psychopathy seems particularly resistant to punishment. Methods We did a case-control functional MRI (fMRI) study in 50 men, of whom 12 were violent off enders with antisocial personality disorder and psychopathy, 20 were violent off enders with antisocial personality disorder but (...)
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  40. Social Machinery and Intelligence.Nello Cristianini, James Ladyman & Teresa Scantamburlo - manuscript
    Social machines are systems formed by technical and human elements interacting in a structured manner. The use of digital platforms as mediators allows large numbers of human participants to join such mechanisms, creating systems where interconnected digital and human components operate as a single machine capable of highly sophisticated behaviour. Under certain conditions, such systems can be described as autonomous and goal-driven agents. Many examples of modern Artificial Intelligence (AI) can be regarded as instances of this class of mechanisms. We (...)
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  41. Moral grandstanding, narcissism, and self-reported responses to the COVID-19 crisis.Joshua B. Grubbs, A. Shanti James, Brandon Warmke & Justin Tosi - 2022 - Journal of Research in Personality 97 (104187):1-10.
    The present study aimed to understand how status-oriented individual differences such as narcissistic antagonism, narcissistic extraversion, and moral grandstanding motivations may have longitudinally predicted both behavioral and social media responses during the early stages of the COVID-19 pandemic. Via YouGov, a nationally representative sample of U.S. adults was recruited in August of 2019 (N = 2,519; Mage = 47.5, SD = 17.8; 51.4% women) and resampled in May of 2020, (N = 1,533). Results indicated that baseline levels of narcissistic antagonism (...)
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  42. Thermal stability of solitons in protein α-helices.Danko D. Georgiev & James F. Glazebrook - 2022 - Chaos, Solitons and Fractals 155:111644.
    Protein α-helices provide an ordered biological environment that is conducive to soliton-assisted energy transport. The nonlinear interaction between amide I excitons and phonon deformations induced in the hydrogen-bonded lattice of peptide groups leads to self-trapping of the amide I energy, thereby creating a localized quasiparticle (soliton) that persists at zero temperature. The presence of thermal noise, however, could destabilize the protein soliton and dissipate its energy within a finite lifetime. In this work, we have computationally solved the system of stochastic (...)
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  43. Quantum tunneling of three-spine solitons through excentric barriers.Danko D. Georgiev & James F. Glazebrook - 2022 - Physics Letters A 448:128319.
    Macromolecular protein complexes catalyze essential physiological processes that sustain life. Various interactions between protein subunits could increase the effective mass of certain peptide groups, thereby compartmentalizing protein α-helices. Here, we study the differential effects of applied massive barriers upon the soliton-assisted energy transport within proteins. We demonstrate that excentric barriers, localized onto a single spine in the protein α-helix, reflect or trap three-spine solitons as effectively as concentric barriers with comparable total mass. Furthermore, wider protein solitons, whose energy is lower, (...)
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  44. A Concept of Discovery.Gary James Jason - 1979 - Journal of Critical Analysis 7 (4):109-118.
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  45. Science and Common Sense.Gary James Jason - 1985 - Journal of Critical Analysis 8 (4):117-123.
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  46. Cosmic Topology, Underdetermination, and Spatial Infinity.Patrick James Ryan - 2024 - European Journal for Philosophy of Science 14 (17):1-28.
    It is well-known that the global structure of every space-time model for relativistic cosmology is observationally underdetermined. In order to alleviate the severity of this underdetermination, it has been proposed that we adopt the Cosmological Principle because the Principle restricts our attention to a distinguished class of space-time models (spatially homogeneous and isotropic models). I argue that, even assuming the Cosmological Principle, the topology of space remains observationally underdetermined. Nonetheless, I argue that we can muster reasons to prefer various topological (...)
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  47. Values for a Post-Pandemic Future.Matthew James Dennis, Georgy Ishmaev, Steven Umbrello & Jeroen van den Hoven (eds.) - 2022 - Cham: Springer.
    This Open Access book shows how value sensitive design (VSD), responsible innovation, and comprehensive engineering can guide the rapid development of technological responses to the COVID-19 crisis. Responding to the ethical challenges of data-driven technologies and other tools requires thinking about values in the context of a pandemic as well as in a post-COVID world. Instilling values must be prioritized from the beginning, not only in the emergency response to the pandemic, but in how to proceed with new societal precedents (...)
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  48. From soul to self.M. James C. Crabbe (ed.) - 1999 - New York: Routledge.
    From Soul to Self takes us on a fascinating journey through philosophy, theology, religious studies and physiological sciences. The contributors explore the relationship between a variety of ideas that have arisen in philosophy, religion and science, each idea seeking to explain why we think we are somehow unique and distinct.
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  49. SNARE proteins as molecular masters of interneuronal communication.Danko D. Georgiev & James F. Glazebrook - 2010 - Biomedical Reviews 21:17-23.
    In the beginning of the 20th century the groundbreaking work of Ramon y Cajal firmly established the neuron doctrine, according to which neurons are the basic structural and functional units of the nervous system. Von Weldeyer coined the term “neuron” in 1891, but the huge leap forward in neuroscience was due to Cajal’s meticulous microscopic observations of brain sections stained with an improved version of Golgi’s la reazione nera (black reaction). The latter improvement of Golgi’s technique made it possible to (...)
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  50. Hay! Apu’ Kung Kayêk: Pagbabakas, Pagpopook, at Pagbubuo sa Dororo Bilang Tagpuan ng Danas, Pangarap, at Pananampalataya ng Katutubong Ayta Ambala.Aeron James De Leon - 2024 - Lakandayang Journal of Cultural Studies 1 (1):53-67.
    In prayers lie the experiences, dreams, and identity of the individual. These strengthen faith while fortifying one’s character. This research examines the Dororo of the Ayta Ambala, a native prayer considered a convergence of the community’s experiences, aspirations, and faith. Using a Filipino-centric research approach (Maka-Pilipinong Pananaliksik), nine Dororo were gathered from Sitio Mampuweng, Olongapo City, Zambales, and classified into three types: Dororong Ritwal, a collective prayer for the community; Dororong Panganganito, a healing ritual; and Pansariling Dororo, personal prayers for (...)
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