The Ramayana and the Mahabharata written in Sanskrit are considered to be the standard texts in India. During the medieval period, the poets have composed these two epics in regional languages incorporating their social elements. While the regional poets maintained the characters of the standard texts constant, the events and functions were variable in their cultural context. The reinterpretation of standard Sanskrit texts in different and diverse contexts was maintained in the vernacular languages and cultures during the medieval period was (...) embedded with many local imaginations connected to these epics. Surdamuni Sarala Das was the first composer of Odia Mahabharata during the 15th Century .His writing was the first of its kind to compose a complete eighteen parvas of the Mahabharata. The Sarala Mahabharata is the foundation of Odia language and has shaped the Odia identity. Surdamuni Sarala Das was an epic singer who mastered the text in his mind through his experience, knowledge, and creativity, and then he wrote the epic poetry in Odia. (shrink)

Berbagai macam aktifitas manusia tidak bisa dipisahkan dari teknologi sebagai wujud alat bantu untuk melaksanakan tugas-tugasnya dengan lebih efektif dan efisien dan terobosan teknologi di bidang informatika telah menghasilkan bentukan teknologi yang berbasis komunikasi yang selain efektif juga bersifat menyenangkan. Media sosial dan game online adalah dua diantara berbagai macam produk hasil pengembangan teknologi di bidang tersebut. Dalam kedua media ini manusia mengalami sebuah perpindahan realitas dari dunia nyata ke dalam dunia virtual. Filsafat teknologi yang dicetuskan oleh Don Ihde digunakan (...) sebagai pisau analisis untuk mengulas dan memahami fenomena ini. Hasil kajian menunjukkan bahwa perubahan persepsi manusia melalui kedua teknologi tersebut dapat mempengaruhi perkembangan budaya secara signifikan. (shrink)

Can reasoning improve moral judgments and lead to moral progress? Pessimistic answers to this question are often based on caricatures of reasoning, weak scientific evidence, and flawed interpretations of solid evidence. In support of optimism, we discuss three forms of moral reasoning (principle reasoning, consistency reasoning, and social proof) that can spur progressive changes in attitudes and behavior on a variety of issues, such as charitable giving, gay rights, and meat consumption. We conclude that moral reasoning, particularly when embedded in (...) social networks with mutual trust and respect, is integral to moral progress. (shrink)

1. Over the last 50 years or so, and especially over the last few decades, the U.S. and many other societies have undergone a large, rapid, and broad decline in anti-gay attitudes. The magnitude, s...

According to Arti Dhand, it can be argued that all Indian ethics have been primarily virtue ethics. Many have indeed jumped on the virtue bandwagon, providing prima facie interpretations of Hindu, Jain, and Buddhist canons in virtue terms. Others have expressed firm skepticism, claiming that virtues are not proven to be grounded in the nature of things and that, ultimately, the appeal to virtue might just well be a mere façon de parler. In this paper, we aim to advance (...) the discussion of Indian virtue ethics. Our intent is not to provide a catch-all interpretation of the different Indian schools. Our goal is, more modestly, to offer a theory of virtues in Indian philosophies, as a framework for theorists and interpreters who see these diverse traditions as amenable to systematic virtue analysis. Our theory grounds virtues in the reality of genuine moral dispositions and in a system of beliefs where morality is understood as transformative in nature. (shrink)

Arguments attempting to debunk moral beliefs, by showing they are unjustified, have tended to be global, targeting all moral beliefs or a large set of them. Popular debunking arguments point to various factors purportedly influencing moral beliefs, from evolutionary pressures, to automatic and emotionally-driven processes, to framing effects. We show that these sweeping arguments face a debunker’s dilemma: either the relevant factor is not a main basis for belief or it does not render the relevant beliefs unjustified. Empirical debunking arguments (...) in ethics can avoid this predicament, but only if they are refocused on highly selective classes of moral belief. Experimental data can combine with familiar consistency reasoning to reveal that like cases are not being treated alike. Selective debunking arguments are unlikely to yield sweeping sceptical conclusions, but they can lead to rational moral change. (shrink)

A Better Ape covers the evolution of morality from the birth of our ape family through the evolution of human species and all the way up to the development of modern societies. In this summary, we highlight several main elements of this account: the co-evolution of morality with intelligence and complex sociality; the role of social institutions and religious morality in the cultural evolution of behaviorally modern humans in prehistory; the increasing complexity of the moral mind through biological evolution in (...) apes, gene-culture co-evolution in various human species, cultural evolution in Homo sapiens, and rational-cultural evolution in recent centuries; and, finally, a cultural evolutionary model of progressive and regressive moral change on which a key factor driving moral progress is social and democratic integration. (shrink)

Twenty-one units of school E-books subjecting in Arts and Culture in total has been released nationwide, which must be consented by Indonesia’s Body of National Standard of Education (Badan Standar Nasional Pendidikan) – the appointed organization to certify Indonesia’s educational features. The graphic instruments applied on cover designs, of which emphasis is merely on technical aspects, requires further examination. Such condition becomes the basis of this study in order to identify, describe and illustrate the implementation of cover designing school E-books (...) subjecting in Arts and Culture through: (1) proficient instructional media’s perspective, (2) visual communication design’s perspective, (3) visual semiotics’ perspective, and (4) end users’ perspective. Additionally, it also qualifies the cover designs. Pertaining qualitative research toward the entire 21 school E-books subjecting in Arts and Culture, the data gathering process involves three sets of instrument:comprehensive reading on visual marks and their relevance with the books’ concepts as cited by C.S. Peirce, corroborative approach toward specialists on both instructional media and visual communication designs, and collective line on end users’ responds. Conclusively, it is found out that: (1) instructional media consultants agree on the significance of all covers, while visual communication designers pronounce that twelve of them are worth it, (2) all covers meet the books’ concepts’ relevance semiotically, (3) students as end-users have positive responds toward all covers, and (4) 12 out of 21 sets of cover design qualify after fulfilling all criteria obliged by this study. Therefore, it recommends: (1) optimal application of visual marks in cover designing process by utilizing e-book features, (2) mature procedure in selecting cover designer(s) to better represent the concept of each book, and (3) intensification on selecting E-book cover designs. The Body of National Standard of Education needs to assess not only technical instruments applied, but also multimedia studies and visual communication designing theories. Further, it is expected to involve both the expertise of visual communication designers and view of the students as targeted end-users in future evaluation process. (shrink)

As Acharya Vidyanand writes in the Foreword of Samayasara, it is the ultimate conscious reality. The enlightened soul has infinite glory. It has the innate ability to demolish the power of karmas, both auspicious as well as inauspicious, which constitute the cycle of births and deaths, and are an obstacle in the path of liberation of the soul. Samayasara is an essential reading for anyone who wishes to lead a purposeful and contented life. It provides irrefutable and lasting solutions to (...) all our problems, concerning worldly ways as well as spiritual curiosities and misgivings. (shrink)

A special feature of Acharya Umasvami’s Tattvarthsutra is that it is the first Jaina scripture written in the Sanskrit language. The work is of great value for the beginner as well as for the learned. Its composition has great charm. Each Sutra is composed in least possible words and can easily be memorized. Many Jains recite these Sutras. -/- Tattvarthsutra is invaluable for understanding life, and pursuit of happiness. The hardships and afflictions that we have to endure are of our (...) own making. Our deeds, driven by passions, lead to sufferings and reproach in this world and in the next. Virtuous activity alone, which is the cause of merit (punya), leads to joyous feeling, auspicious life, charming and lustrous physique, and high status. Our ultimate goal is the attainment of the divine attributes, in fullness and perfection, of our souls. We can reach our goal only through the three-fold path of right faith, right knowledge and right conduct. (shrink)

The National Cancer Institute’s Thesaurus (NCIT) has been created with the goal of providing a controlled vocabulary which can be used by specialists in the various sub-domains of oncology. It is intended to be used for purposes of annotation in ways designed to ensure the integration of data and information deriving from these various sub-domains, and thus to support more powerful cross-domain inferences. In order to evaluate its suitability for this purpose, we examined the NCIT’s treatment of the kinds of (...) entities which are fundamental to an ontology of colon carcinoma. We here describe the problems we uncovered concerning classification, synonymy, relations and definitions, and we draw conclusions for the work needed to establish the NCIT as a reference ontology for the cancer domain in the future. (shrink)

Bārasa Aņuvekkhā – ‘The Twelve Contemplations’ – of Ācārya Kundakunda (circa 1st century BC) contains 91 verses (gāthā). ‘Aņuvekkhā’, ‘aņupekkhā’, ‘anuprekşā’, and ‘bhāvanā’ are synonyms; these terms are used in Prākrit, Apabhramśa, Sanskrit and Hindi languages, respectively. Contemplation means ‘meditating on the nature of the Reality’. The uniqueness of Ācārya Kundakunda’s exposition is that he has described each contemplation both from the empirical (vyavahāra) as well as the transcendental (niścaya) points-of-view (naya). These contemplations help a man practise moral virtues, like (...) forbearance (kşamā), and lead to highly effective stoppage (samvara) of karmas. He who does contemplation observes properly the moral virtues and also endures the afflictions. (shrink)

Ātmānuśāsana (commonly spelled as Atmanushasan) by Ācārya Guņabhadra presents profound concepts of the Jaina Doctrine in a form that is easily understood. Remarkable for its poetry and meaning, it expounds that right faith (samyagdarśana) is the cause of merit, and wrong faith of demerit. To have belief in the true nature of substances is right faith. Dharma is the man’s most excellent possession. The conduct that leads to merit is dharma and it results in happiness after destroying misery. Whether happy (...) or miserable, dharma should be the only pursuit of man. True happiness is not the momentary sprinkling of the pleasures of the senses. Long-life, wealth and sound body are obtained from the previously earned merit (puņya). Under the spell of sinful karmas, the man experiences misery. Excellent men with discrimination work hard, incessantly and cheerfully, for the sake of their future lives. The happiness attained through austerity (tapa) can never be attained by craving for wealth. No dust of disgrace ever touches the feet of the man fortified by austerity. The ascetic goes on to perform austerity while protecting his body, for a very long time. Through the power of austerity he vanquishes his natural enemies, like the passions of anger, etc. In the after-life, he automatically and speedily attains liberation as the culmination of his human effort. (shrink)

In one of his earliest dialogues, the Soliloquia, Augustine identifies the liberal arts (disciplinae) with truth (veritas), and employs this somewhat puzzling identification as a premise in his infamous proof of the immortality of the soul (Sol. 2.24). In this paper, I examine Augustine’s argument for this peculiar identification. Augustine maintains both (1) that the constituent propositions of the liberal arts are true, and (2) that the liberal art of dialectic (disciplina disputandi) is the “truth through which all disciplines are (...) true” (Sol. 2.21). I argue that Augustine identifies the liberal arts with truth because (1) the constituent propositions of the liberal arts are learned, and (2) dialectic’s structure is essential to the liberal arts. I further suggest that the subject matter of each liberal art reflects a distinct segment of intelligible reality, that is, the realm of the intelligible Forms. (shrink)

An explicit formal-ontological representation of entities existing at multiple levels of granularity is an urgent requirement for biomedical information processing. We discuss some fundamental principles which can form a basis for such a representation. We also comment on some of the implicit treatments of granularity in currently available ontologies and terminologies (GO, FMA, SNOMED CT).

AI-powered records science is revolutionizing the way facts are analyzed and understood. It can significantly improve the exceptional of information evaluation and boost its speed. AI-powered facts technological know-how enables access to more extensive, extra complicated information sets, faster insights, faster trouble solving, and higher choice making. Using the use of AI-powered information technological know-how techniques and tools, organizations can provide more accurate outcomes with shorter times to choices. AI-powered facts technology also offers more correct predictions of activities and developments (...) and superior accuracy in sample reputation.Furthermore, AI-powered facts science techniques can help agencies discover anomalies in datasets, learn new patterns, and better understand the points. This paper discusses the advantages of AI-powered statistics science and how it may enhance data analysis. It additionally discusses a number of the challenges going through organizations in imposing AI-powered records science projects and gives excellent practices for deploying and coping with records technology projects. (shrink)

Aptamimamsa by Ācārya Samantabhadra (2nd century CE) starts with a discussion, in a philosophical-cum-logical manner, on the Jaina concept of omniscience and the attributes of the Omniscient. The Ācārya questions the validity of the attributes that are traditionally associated with a praiseworthy deity and goes on to establish the logic of accepting the Omniscient as the most trustworthy and praiseworthy Supreme Being. Employing the doctrine of conditional predications (syādvāda) – the logical expression of reality in light of the foundational principle (...) of non-absolutism (anekāntavāda) – he faults certain conceptions based on absolutism. He finally elucidates correct perspectives on issues including fate and human-effort, and bondage of meritorious (punya) or demeritorious (pāpa) karmas. (shrink)

The Unified Medical Language System and the Gene Ontology are among the most widely used terminology resources in the biomedical domain. However, when we evaluate them in the light of simple principles for wellconstructed ontologies we find a number of characteristic inadequacies. Employing the theory of granular partitions, a new approach to the understanding of ontologies and of the relationships ontologies bear to instances in reality, we provide an application of this theory in relation to an example drawn from the (...) context of the pathophysiology of hypertension. This exercise is designed to demonstrate how, by taking ontological principles into account we can create more realistic biomedical ontologies which will also bring advantages in terms of efficiency and robustness of associated software applications. (shrink)

that can serve as a foundation for more refined ontologies in the field of proteomics. Standard data sources classify proteins in terms of just one or two specific aspects. Thus SCOP (Structural Classification of Proteins) is described as classifying proteins on the basis of structural features; SWISSPROT annotates proteins on the basis of their structure and of parameters like post-translational modifications. Such data sources are connected to each other by pairwise term-to-term mappings. However, there are obstacles which stand in the (...) way of combining them together to form a robust meta-classification of the needed sort. We discuss some formal ontological principles which should be taken into account within the existing datasources in order to make such a metaclassification possible, taking into account also the Gene Ontology (GO) and its application to the annotation of proteins. (shrink)

Clinical guidelines are special types of plans realized by collective agents. We provide an ontological theory of such plans that is designed to support the construction of a framework in which guideline-based information systems can be employed in the management of workflow in health care organizations. The framework we propose allows us to represent in formal terms how clinical guidelines are realized through the actions of are realized through the actions of individuals organized into teams. We provide various levels of (...) implementation representing different levels of conformity on the part of health care organizations. Implementations built in conformity with our framework are marked by two dimensions of flexibility that are designed to make them more likely to be accepted by health care professionals than standard guideline-based management systems. They do justice to the fact 1) that responsibilities within a health care organization are widely shared, and 2) that health care professionals may on different occasions be non-compliant with guidelines for a variety of well justified reasons. The advantage of the framework lies in its built-in flexibility, its sensitivity to clinical context, and its ability to use inference tools based on a robust ontology. One disadvantage lies in its complicated implementation. (shrink)

The International Classification of Functioning, Disability and Health provides a classification of human bodily functions, which, while exhibiting non-conformance to many formal ontological principles, provides an insight into which basic functions such a classification should include. Its evaluation is an important first step towards such an adequate ontology of this domain. Presented at the 13th Annual North American WHO Collaborating Center Conference on the ICF, 2007.

Dravyasamgraha is one of the finest classical Jaina texts, composed by His Holiness Acarya Nemichandra (c. 10th century CE). It deals primarily with the Realities (tattvas) that contribute to world process. The conduct required for attaining the ultimate goal of liberation follows from the knowledge of these Realities. Both, the transcendental and the empirical points of view, have been considered while explaining the nature of substances, souls and non-souls.

The theory of granular partitions (TGP) is a new approach to the understanding of ontologies and other classificatory systems. The paper explores the use of this new theory in the treatment of task-based clinical guidelines as a means for better understanding the relations between different clinical tasks, both within the framework of a single guideline and between related guidelines. We used as our starting point a DAML+OIL-based ontology for the WHO guideline for hypertension management, comparing this with related guidelines and (...) attempting to show that TGP provides a flexible and highly expressive basis for the manipulation of ontologies of a sort which might be useful in providing more adequate Computer Interpretable Guideline Models (CIGMs) in the future. (shrink)

Soul substance (jīva dravya) is ubiquitous but unseen. Driving force within each one of us, it has been, since time immemorial, a subject matter of research by philosophers, religious leaders and laity. Still, ambiguity and misconceptions prevail as regard its real nature. Some negate the existence of soul and attribute consciousness to the union of four basic substances – earth (prthvī), water (jala), fire (agni), and air (vāyu); death leads to its annihilation. Some believe it to be momentary, devoid of (...) self-existence. Still others consider it a product of illusion (māyā) or ignorance (avidyā) as all objects are manifestations of Brahma; only the one eternally undivided Brahma exists. All such conceptions are based on absolutism like: existence (bhāvaikānta) and non-existence (abhāvaikānta), non-dualism (advaita-ekānta) and separateness (prthaktva-ekānta), and permanence (nityatva-ekānta) and momentariness (ksanika-ekānta). Jaina epistemology goes beyond the superficial and examines objects of knowledge from all possible points of view. It asserts that the entity (dharmī) and its attributes (dharma) are neither absolutely dependent (āpeksika) nor absolutely independent (anāpeksika). Only an entity which has general (sāmānya – concerning the substance, dravya) and particular (viśesa – concerning the mode, paryāya) attributes can be the subject of knowledge. Substance without its modification and modification without its substance cannot be the subject of valid knowledge; only their combination can be the subject of knowledge. (shrink)

The MgAl2O4 spinel doped with Eu2+ ions powder phosphor was prepared at temperature as low as 500 oC using the combustion route. A structural property of the powder was characterized by X-ray diffraction (XRD). This XRD pattern shows the well crystallized cubic phase, Fd-3m space group of MgAl2O4. The estimated average crystalline size is about 36 and 30 nm for MgAl2O4 and Eu doped MgAl2O4 particles respectively. The photoluminescent property of prepared powder was investigated using excitation and emission spectroscopy at (...) room temperatures. Energy levels scheme is proposed for emission from MgAl2O4: Eu2+. (shrink)

Causal models of agents have been used to analyse the safety aspects of machine learning systems. But identifying agents is non-trivial -- often the causal model is just assumed by the modeler without much justification -- and modelling failures can lead to mistakes in the safety analysis. This paper proposes the first formal causal definition of agents -- roughly that agents are systems that would adapt their policy if their actions influenced the world in a different way. From this we (...) derive the first causal discovery algorithm for discovering agents from empirical data, and give algorithms for translating between causal models and game-theoretic influence diagrams. We demonstrate our approach by resolving some previous confusions caused by incorrect causal modelling of agents. (shrink)

Bhaktāmara Stotra is the magnum opus composition of Ācārya Mānatunga (circa 7th century CE). Bhaktāmara Stotra eulogizes the supreme attributes of Lord Ādinātha, the first Tīrthaṅkara. This is perhaps the most well-known adoration of Lord Jina that is not only recited but memorized, with great devotion and reverence, by a large number of people among the Jaina community, Digambara and Śvetāmbara. It is believed that the worthy soul accumulates enormous propitiousness by reading Bhaktāmara Stotra with devotion. Hundreds of thousands of (...) instances, ancient and recent, must have come to light where people claimed to have benefitted miraculously by the recitation of and reflection on this sacred composition. This slim volume is a useful reference text for international readers. It will be of interest not only to Hindi-loving scholars but also to those looking for an authentic English rendering of Bhaktāmara Stotra. Besides the transliteration in English of the original Sanskrit verse, the meaning of each verse has been given both in Hindi and English languages. The Preface of the book contains, besides other useful information, a synopsis of the concept of empirical (vyavahāra) time (kāla), and a brief life-story of Lord Ādinātha, the first Tīrthaṅkara, as expounded in the Scripture. (shrink)

Numerous high-profile ethics scandals, rising inequality, and the detrimental effects of climate change dramatically underscore the need for business schools to instill a commitment to social purpose in their students. At the same time, the rising financial burden of education, increasing competition in the education space, and overreliance on graduates’ financial success as the accepted metric of quality have reinforced an instrumentalist climate. These conflicting aims between social and financial purpose have created an existential crisis for business education. To resolve (...) this impasse, we draw on the concept of moral self-awareness to offer a system-theoretical strategy for crowding-in a culture of ethics within business schools. We argue that to do so, business schools will need to (1) reframe the purpose of business, (2) reframe the meaning of professional success, and (3) reframe the ethos of business education itself. (shrink)

General perception that money can buy happiness has been refuted in this article.

Evidence-based medicine relies on the execution of clinical practice guidelines and protocols. A great deal of of effort has been invested in the development of various tools which automate the representation and execution of the recommendations contained within such guidelines and protocols by creating Computer Interpretable Guideline Models (CIGMs). Context-based task ontologies (CTOs), based on standard terminology systems like UMLS, form one of the core components of such a model. We have created DAML+OIL-based CTOs for the tasks mentioned in the (...) WHO guideline for hypertension management, drawing comparisons also with other related guidelines. The advantages of CTOs include: contextualization of ontologies, providing ontologies tailored to specific aspects of the phenomena of interest, dividing the complexity involved in creating ontologies into different levels, providing a methodology by means of which the task recommendations contained within guidelines can be integrated into the clinical practices of a health care set-up. (shrink)

The Gene Ontology is an important tool for the representation and processing of information about gene products and functions. It provides controlled vocabularies for the designations of cellular components, molecular functions, and biological processes used in the annotation of genes and gene products. These constitute three separate ontologies, of cellular components), molecular functions and biological processes, respectively. The question we address here is: how are the terms in these three separate ontologies related to each other? We use statistical methods and (...) formal ontological principles as a first step towards finding answers to this question. (shrink)

Kalyāņamandira Stotra (Pārśvanātha Stotra) is the magnum opus composition of Ācārya Kumudacandra (circa 12th century VS). Kalyāņamandira Stotra eulogizes the supreme attributes of Lord Pārśvanātha, the twenty-third Tīrthaṅkara. This is perhaps the most well-known adoration of Lord Pārśvanātha that is not only recited but memorized, with great devotion and reverence, by many among the Jaina community, both Digambara and Śvetāmbara. The worthy soul is believed to accumulate enormous propitiousness by reading Kalyāņamandira Stotra with devotion. Many claim to have benefitted miraculously (...) from the recitation of and reflection on this sacred composition. This slim volume is a useful reference text for international readers. It will be of interest not only to the Hindi-loving scholars but also to those looking for an authentic English rendering of Kalyāņamandira Stotra. Besides other useful information, the book’s Preface contains a brief life story of Lord Pārśvanātha, as expounded in the Scripture. The interesting and eye-opening sequence of the enmity carried forward by various incarnations of Kamaṭha (finally, Śambara deva) against his then-younger brother Marubhūti (finally, Lord Pārśvanātha), is also provided in a tabular form. (shrink)

Ācārya Kundakunda’s (circa 1st century BCE) Pravacanasāra is among the most popular Jaina Scriptures that are studied with great reverence by the ascetics as well as the laymen. Consciousness manifests in form of cognition (upayoga) – pure-cognition (śuddhopayoga), auspicious-cognition (śubhopayoga) and inauspicious-cognition (aśubhopayoga). Pure-cognition represents conduct without-attachment (vītarāga cāritra). Perfect knowledge or omniscience (kevalajñāna) is the fruit of pure-cognition (śuddhopayoga). The soul engaged in pure-cognition (śuddhopayoga) enjoys supreme happiness engendered by the soul itself; this happiness is beyond the five senses (...) – atīndriya – unparalleled, infinite, and imperishable. Omniscience (kevalajñāna) is real happiness; there is no difference between knowledge and happiness. Delusion (moha), the contrary and ignorant view of the soul about substances, is the cause of misery. The soul with attachment (rāga) toward the external objects makes bonds with karmas and the soul without attachment toward the external objects frees itself from the bonds of karmas. The stainless soul knows the reality of substances, renounces external and internal attachments (parigraha) and does not indulge in the objects-of-the-senses. (shrink)

Ācārya Kundakunda’s (circa 1st century BCE) Rayaṇasāra makes it clear that the right-faith (samyagdarśana) is the beginning as well as the culmination of the path to liberation – mokṣa-mārga. The householder (śrāvaka) must first acquire the right-faith – the Quintessential Jewel (Rayaṇasāra) – to be able to establish his Self on to the path to liberation. As he acquires the right-faith he begins to appreciate the reality of the world and the worldly-existence. He then exerts to acquire the true knowledge (...) (jñāna) as expounded in the Doctrine (siddhānta), and adopts the laudable conduct (cāritra) by becoming a digambara-ascetic (nirgrantha muni). He ascends the spiritual-stages (guṇasthāna) and ultimately, through pure-meditation (śukla-dhyāna), attains the ineffable and eternal bliss appertaining to liberation (mokṣa). Ācārya Kundakunda, all through this Holy Scripture Rayaṇasāra, underscores the importance of the right-faith (samyagdarśana) for the householder (śrāvaka) as well as the ascetic (muni, śramaṇa). He asserts that in the (present) unfavourable fifth era the study – svādhyāya – of the Scripture, indeed, is meditation (dhyāna); it results in the subjugation of the five-senses (paṅcendriya) as well as of the passions (kaṣāya). (shrink)

Shri Amritchandra Suri’s Purusārthasiddhyupāya is a matchless Jaina text that deals with the conduct required of the householder (śrāvaka). In no other text that deals with the conduct required of the householder we see the same treatment of complex issues such as the transcendental and the empirical points of view, cause and effect relationships, and injury and non-injury, maintaining throughout the spiritual slant. The basic tenet of Jainism – non-injury or Ahimsā – has been explained in detail in the book.

Recent work on the quality assurance of the Gene Ontology (GO, Gene Ontology Consortium 2004) from the perspective of both linguistic and ontological organization has made it clear that GO lacks the kind of formalism needed to support logic-based reasoning. At the same time it is no less clear that GO has proven itself to be an excellent terminological resource that can serve to combine together a variety of biomedical database and information systems. Given the strengths of GO, it is (...) worth investigating whether, by overcoming some of its weaknesses from the point of view of formal-ontological principles, we might not be able to enhance a version of GO which can come even closer to serving the needs of the various communities of biomedical researchers and practitioners. It is accepted that clinical and bioinformatics need to find common ground if the results of data-intensive biomedical research are to be harvested to the full. It is also widely accepted that no single method will be sufficient to create the needed common framework. We believe that the principles-based approach to life-science data integration and knowledge representation must be one of the methods applied. Indeed in dealing with the ontological representation of carcinomas, and specifically of colon carcinomas, we have established that, had GO (and related biomedical ontologies) followed some of the basic formal-ontological principles we have identified (Smith et al. 2004, Ceusters et al. 2004), then the effort required to navigate successfully between clinical and bioinformatics systems would have been reduced. We point here to the sources of ontologically-related errors in GO, and also provide arguments as to why and how such errors need to be resolved. (shrink)

It is widely understood that protein functions can be exhaustively described in terms of no single parameter, whether this be amino acid sequence or the three-dimensional structure of the underlying protein molecule. This means that a number of different attributes must be used to create an ontology of protein functions. Certainly much of the required information is already stored in databases such as Swiss-Prot, Protein Data Bank, SCOP and MIPS. But the latter have been developed for different purposes and the (...) separate data-structures which they employ are not conducive to the needed data integration. When we attempt to classify the entities in the domain of proteins, we find ourselves faced with a number of cross-cutting principles of classification. Our question here is: how can we bring together these separate taxonomies in order to describe protein functions? Our proposed answer is: via a careful top-level ontological analysis of the relevant principles of classification, combined with a new framework for the simultaneous manipulation of classifications constructed for different purposes. (shrink)

Istopadesa by Acarya Pujyapada is a concise work of 51 didactic verses leading the reader from the empirical to the transcendental, from the mundane to the sublime, through an experiential process of self-realization, rather than through a metaphysical study of the soul-nature. Concise but deep in import, Istopadesa unambiguously establishes the glory of the Self. It is an essential reading for the ascetic. The householder too who ventures to study it stands to benefit much as the work establishes the futility (...) of the worldly objects and pursuits, and strengthens right faith, the basis for all that is good and virtuous. (shrink)

Acarya Samantabhadra’s Svayambhustotra (2nd century CE) is a fine composition in Sanskrit dedicated to the adoration of the Twenty-four Tîrthankara, the Most Worshipful Supreme Beings. Acarya Samantabhadra was one of the most impelling proponents of the Jaina doctrine of anekantavada, a philosophical system which maintains that reality has multifarious aspects and that a complete apprehension of it must necessarily take into account all these aspects. Non-appreciation of this jewel of Jainism has caused the other philosophical systems fall into the trap (...) of one-sided, incomplete, and unsustainable dogmas that fail to explain the Truth. Through its 143 verses Svayambhustotra not only enriches reader’s devotion, knowledge, and conduct but also frees his mind from blind faith and superstitions. Rid of ignorance and established firmly in right faith, the reader’s mind experiences ineffable tranquility and equanimity. As proclaimed by Acarya 108 Vidyanand Muni, Svayambhustotra is an essential reading for all – ascetics and laymen. (shrink)

Ontological principles are needed in order to bridge the gap between medical and biological information in a robust and computable fashion. This is essential in order to draw inferences across the levels of granularity which span medicine and biology, an example of which include the understanding of the roles of tumor markers in the development and progress of carcinoma. Such information integration is also important for the integration of genomics information with the information contained in the electronic patient records in (...) such a way that real time conclusions can be drawn. In this paper we describe a large multi-granular datasource built by using ontological principles and focusing on the case of colon carcinoma. (shrink)

(Report assembled for the Workshop of the AMIA Working Group on Formal Biomedical Knowledge Representation in connection with AMIA Symposium, Washington DC, 2005.) Best practices in ontology building for biomedicine have been frequently discussed in recent years. However there is a range of seemingly disparate views represented by experts in the field. These views not only reflect the different uses to which ontologies are put, but also the experiences and disciplinary background of these experts themselves. We asked six questions related (...) to biomedical ontologies to what we believe is a representative sample of ontologists in the biomedical field and came to a number conclusions which we believe can help provide an insight into the practical problems which ontology builders face today. (shrink)

There are a number of existing classifications and staging schemes for carcinomas, one of the most frequently used being the TNM classification. Such classifications represent classes of entities which exist at various anatomical levels of granularity. We argue that in order to apply such representations to the Electronic Health Records one needs sound ontologies which take into consideration the diversity of the domains which are involved in clinical bioinformatics. Here we outline a formal theory for addressing these issues in a (...) way that the ontologies can be used to support inferences relating to entities which exist at different anatomical levels of granularity. Our case study is the colon carcinoma, one of the most common carcinomas prevalent within the European population. (shrink)

An important part of the Unified Medical Language System (UMLS) is its Semantic Network, consisting of 134 Semantic Types connected to each other by edges formed by one or more of 54 distinct Relation Types. This Network is however for many purposes overcomplex, and various groups have thus made attempts at simplification. Here we take this work further by simplifying the relations which involve the three Semantic Types – Diagnostic Procedure, Laboratory Procedure and Therapeutic or Preventive Procedure. We define operators (...) which can be used to generate terms instantiating types from this selected set when applied to terms designating certain other Semantic Types, including almost all the terms specifying clinical tasks. Usage of such operators thus provides a useful and economical way of specifying clinical tasks. The operators allow us to define a mapping between those types within the UMLS which do not represent clinical tasks and those which do. This mapping then provides a basis for an ontology of clinical tasks that can be used in the formulation of computer-interpretable clinical guideline models. (shrink)

The paper presents the outlines of an ontology of plans and guidelines, which is then used as the basis for a framework for implementing guideline-based systems for the management of workflow in health care organizations. The framework has a number of special features, above all in that it enables us to represent in formal terms assignments of work-items both to individuals and to teams and to tailor guideline to specific contexts of application in health care organizations. It is designed also (...) to enable implementations to do justice to the fact that the processes carried out in health care organizations may deviate in different ways from the norms set forth in corresponding guideline definitions. This means that implementations built in conformity with the framework will be marked by a type of flexibility that might make them more likely to be accepted by healthcare professionals than are standard guideline-based management systems. (shrink)

Outcomes research in healthcare has been a topic much addressed in recent years. Efforts in this direction have been supplemented by work in the areas of guidelines for clinical practice and computer-interpretable workflow and careflow models.In what follows we present the outlines of a framework for understanding the relations between organizations, guidelines, individual patients and patient-related functions. The derived framework provides a means to extract the knowledge contained in the guideline text at different granularities, in ways that can help us (...) to assign tasks within the healthcare organization and to assess clinical performance in realizing the guideline. It does this in a way that preserves the flexibility of the organization in the adoption of the guidelines. (shrink)

We provide a methodology for the creation of ontological partitions in biomedicine and we test the methodology via an application to the phenomenon of blood pressure. An ontology of blood pressure must do justice to the complex networks of intersecting pathways in the organism by which blood pressure is regulated. To this end it must deal not only with the anatomical structures and physiological processes involved in such regulation but also with the relations between these at different levels of granularity. (...) For this purpose our ontology offers a variety of distinct partitions � of substances, processes and functions � and integrates these together within a single framework via transitive networks of part-whole and dependence relations among the entities in each of these categories. The paper concludes with a comparison of this methodology with the approaches of GOTM, KEGG, DIP and BIND and provides an outline of how the methodology is currently being applied in the field of biomedical database integration. (shrink)

Hierarchy and inequality are deeply rooted in Indian tradition. They are found in practice in the form of unequal placement of caste and class groups in the civilizing system of Indian society. The notions of dharma (normative order), karma (personnel moral commitment) and jāti (caste) that constitute the basic principles of Indian culture, making the Indian cultural tradition a unique cultural tradition, are also the principles of hierarchy and social stratification. In this paper, an attempt has been made to present (...) a comprehensive and investigative view of different scholars concerning the deep-rooted traditional characteristics of caste in Indian society. (shrink)

Ālāpa Paddhati, composed by Ācārya Devasena (c. tenth century, Vikrama Samvat) is a Jaina text primarily on the topics of the standpoints (naya) and the secondary-standpoints (upanaya). It also delves into the substances (dravya), their qualities or attributes (guṇa), modes (paryāya), and nature (svabhāva). It is true that without appreciating the import and applicability of the individual standpoints (naya), one may get lost in the complex maze of the standpoints and cause great harm to one’s understanding, and even to one’s (...) mental balance. Ālāpa Paddhati is essential reading for every serious reader of the Dravyānuyoga that spreads the light of right (scriptural) knowledge by illuminating the Reality of substances – soul (jīva) and non-soul (ajīva), merit (puṇya) and demerit (pāpa), bondage (bandha) and liberation (mokṣa), including influx (āsrava), stoppage (saṃvara), and gradual dissociation (nirjarā). The book has a useful Appendix that explains the doctrines of non-absolutism (anekāntavāda) and conditional predication (syādvāda). This slim volume needs to be read over and over again to internalize the underlying concepts fully. (shrink)

As Āchārya Vidyanand writes in the Foreword of Samayasāra, it is the ultimate conscious reality. The enlightened soul has infinite glory. It has the innate ability to demolish karmas, both auspicious as well as inauspicious, which constitute the cycle of births and deaths, and are obstacles in the path to liberation. Samayasāra is an essential reading for anyone who wishes to lead a purposeful and contented life. It provides irrefutable and lasting solutions to all our problems, concerning worldly ways as (...) well as spiritual curiosities and misgivings. (shrink)

The canonical text ‘Dravyasamgraha’ is believed to have been composed either by the Most Worshipful Ācārya Nemicandra ‘Siddhānta Cakravartī’ (circa 10th century CE) – the celebrated composer of Texts like Gommatasāra, Labdhisāra, and Trilokasāra – or by his later namesake Muni Nemicandra ‘Siddāntideva’ (circa the end of 11th century CE). Ācārya (Muni) Nemicandra’s Dravyasamgraha consists of just 58 verses. In 116 lines of 58 verses, the author has described the six substances (dravya), five with bodily-existence (pañcāstikāya), seven realities (tattva), nine (...) objects (padārtha), and the path to liberation (mokşa), from both the empirical (vyavahāra) as well as the transcendental (niścaya) points-of-view (naya). The treatise ends with a brief description of the five Supreme-beings (pañca-parameşthī) and of meditation (dhyāna). The ‘Explanatory Note’ against each verse comprises excerpts from the most authentic Sacred Jaina Texts. This is a thoroughly revised second edition of an earlier work published in 2013. (shrink)