Werner Heisenberg made an important – and as yet insufficiently researched – contribution to the transformation of the modern conception of science. This transformation involved a reassessment of the status of scientific knowledge from certain to merely hypothetical – an assessment that is widely recognized today. I examine Heisenberg’s contribution in particular by taking his conception of “closed theories” as an example according to which the established physical theories have no universal and exclusive, but only a restricted validity. (...) Firstly, I characterize the historical process of hypothetization of claims to validity. Then, secondly, I reconstruct Heisenberg’s conception, as far as it can be derived from his popular writings, relating it to the process of hypothetization. Finally, I touch on the history of its reception and compare it with conceptions of science that emphasize the significance of the hypothetical for the modern theories of natural sciences. Compared to these conceptions, Heisenberg’s contribution turns out to be rather independent. (shrink)

Werner Heisenberg hat einen wichtigen, noch nicht hinreichend untersuchten Beitrag zum Wandel des neuzeitlichen Wissenschaftsverständnisses geleistet. Der Wandel führte von der Charakterisierung des wissenschaftlichen Wissens als sichere Erkenntnis zu seiner - heute weithin anerkannten - Charakterisierung als bloß hypothetische Erkenntnis. Anfänge dieses Wandlungsprozesses lassen sich im 19. Jahrhundert nachweisen (z.B. bei John Hersehel, William Whewell oder Hermann von Helmholtz). Ich möchte am Beispiel von Heisenberg der Frage nachgehen, welchen Einfluss die Begründung der Quantenmechanik, die seine Wissenschaftsauffassung prägte, auf den Prozess (...) der Relativierung von Geltungsansprüchen hatte. Meine Vermutung ist, dass eine entscheidende Rolle hierbei weniger dem Wahrscheinlichkeitsbegriff als vielmehr dem Wahrheits- und Realitätsbegriff zukam. Ich werde als erstes den historischen Prozess der Hypothetisierung von Geltungsansprüchen, zu dem ich Heisenbergs Konzeption ins Verhältnis setzen möchte, charakterisieren. Anschließend rekonstruiere ich Heisenbergs Konzeption, soweit sie sich seinen populären Reden und Aufsätzen entnehmen lässt. Als drittes werde ich ihre Wirkungsgeschichte kurz ansprechen und sie mit Wissenschaftsauffassungen vergleichen, die die Bedeutung des Hypothetischen für die modernen Theorien der Naturwissenschaften betonen. Ihnen gegenüber erweist sich Heisenbergs Beitrag als durchaus eigenständig. (shrink)

Do the changes that have taken place in the structures and methods of the production of scientific knowledge and in our understanding of science over the past fifty years justify speaking of an epochal break in the development of science? Gregor Schiemann addresses this issues through the notion of a scientific revolution and claims that at present we are not witnessing a new scientific revolution. Instead, Schiemann argues that after the so-called Scientific Revolution in the (...) sixteenth and seventeenth centuries, a caesura occurred in the course of the nineteenth century that constituted a departure from the early modern origins of science. This change was characterized by the loss of certainty on the part of the scientists, by the steadily increasing importance of scientific communities (rather than individuals), and by the systematic intertwinement of scientific and societal development. As to present science, Schiemann admits that important changes have occurred, but he denies the conflation of nature and culture: even the OncoMouse is a natural organism, though a seriously damaged one. (shrink)

The essay is an English version of the German article "Wissenschaftliche Rationalität, menschliches Bewusstsein und pro-religiöse Ideen". It discusses immanent versus transcendent concepts in the context of the art of living, as well as the understanding of human consciousness in the context of religion. Science provides us with a far reaching understanding of natural processes, including biological evolution, but also with deep insights into its own intrinsic limitations. This is consistent with more than one interpretation on the “metatheoretical“, that is (...) on the philosophical and cultural level, including liberal, enlightened forms of religion as well as agnostic views. Choices and preferences are mainly a matter of wisdom and art of living, and not just of knowledge, and this, in my view, supports metaphysical and anthropological optimism as expressed in liberal pro-religious ideas. Within Christian theology, metaphysical optimism and openness are most characteristic for the ideas of “apokatastasis” – “salvation for all” - repeatedly condemned as heretical, but also widely supported from early Christianity to modern times. (shrink)

In his latest attack, even though he claims to be a practitioner of “close reading” (Wills 2018b, 34), it appears that Wills still has not bothered to read the paper in which I defend the thesis he seeks to attack (Mizrahi 2017a), or any of the papers in my exchange with Brown (Mizrahi 2017b; 2018a), as evidenced by the fact that he does not cite them at all. This explains why Wills completely misunderstands Weak Scientism and the arguments for the (...) quantitative superiority (in terms of research output and research impact) as well as qualitative superiority (in terms of explanatory, predictive, and instrumental success) of scientific knowledge over non-scientific knowledge. (shrink)

In Posterior Analytics 71b9 12, we find Aristotle’s definition of scientific knowledge. The definiens is taken to have only two informative parts: scientific knowledge must be knowledge of the cause and its object must be necessary. However, there is also a contrast between the definiendum and a sophistic way of knowing, which is marked by the expression “kata sumbebekos”. Not much attention has been paid to this contrast. In this paper, I discuss Aristotle’s definition paying (...) due attention to this contrast and to the way it interacts with the two conditions presented in the definiens. I claim that the “necessity” condition ammounts to explanatory appropriateness of the cause. (shrink)

With increasing publication and data production, scientific knowledge presents not simply an achievement but also a challenge. Scientific publications and data are increasingly treated as resources that need to be digitally ‘managed.’ This gives rise to scientific Knowledge Management : second-order scientific work aiming to systematically collect, take care of and mobilise first-hand disciplinary knowledge and data in order to provide new first-order scientific knowledge. We follow the work of Leonelli, Efstathiou (...) and Hislop in our analysis of the use of KM in semantic systems biology. Through an empirical philosophical account of KM-enabled biological research, we argue that KM helps produce new first-order biological knowledge that did not exist before, and which could not have been produced by traditional means. KM work is enabled by conceiving of ‘knowledge’ as an object for computational science: as explicated in the text of biological articles and computable via appropriate data and metadata. However, these founded knowledge concepts enabling computational KM risk focusing on only computationally tractable data as knowledge, underestimating practice-based knowing and its significance in ensuring the validity of ‘manageable’ knowledge as knowledge. (shrink)

Science and scientific knowledge have been questioned in many ways for a long period of time. Especially, after the scientific revolution of 16th- and 17th-century Europe, science and its knowledge have been mainly accepted one of the most valuable and trustable information. However, in 20th century, autonomy of scientific knowledge and its dominant position over other kinds of knowledge have been mainly criticised. Social and other factors that were tried to be excluded before (...) have been incorporated into the work by the influence of the Strong Programme. In this article, it will be argued that while people are presenting scientific knowledge, their interests, beliefs and the communities they are involved in are also shown to be effective in producing this information. Thus, the desired result is that it is not reasonable to talk about the absolute autonomy of scientific knowledge. (shrink)

Pragmatic encroachment theories of knowledge may be characterized as views according to which practical factors may partly determine the truth-value of ascriptions that S knows that p – even though these factors do not partly determine S’s belief that p or p itself. The pros and cons of variations of pragmatic encroachment are widely discussed in epistemology. But despite a long pragmatist tradition in the philosophy of science, few efforts have been devoted to relate this particular view to issues (...) in philosophy of science. Consequently, a central aim of the present paper is to consider how the contemporary debates over pragmatic encroachment connect to philosophy of science. More specifically, I will set forth some arguments against the idea of pragmatic encroachment on scientific knowledge. Moreover, I will argue that it is not plausible to respond to these arguments by embedding pragmatic encroachment in the anti-realist framework of constructive empiricism. So, I conclude that there are good reasons to reject pragmatic encroachment theories of scientific knowledge. (shrink)

Aristotle was the first thinker to articulate a taxonomy of scientific knowledge, which he set out in Posterior Analytics. Furthermore, the “special sciences”, i.e., biology, zoology and the natural sciences in general, originated with Aristotle. A classical question is whether the mathematical axiomatic method proposed by Aristotle in the Analytics is independent of the special sciences. If so, Aristotle would have been unable to match the natural sciences with the scientific patterns he established in the Analytics. In (...) this paper, I reject this pessimistic approach towards the scientific value of natural sciences. I believe that there are traces of biology in the Analytics as well as traces of the Analytics’ theory in zoological treatises. Moreover, for a lack of chronological clarity, I think it’s better to unify Aristotle’s model of scientific research, which includes Analytics and the natural sciences together. (shrink)

From the Scientific Revolution to the present era, the natural sciences have developed remarkably and recorded colossal success in different areas such as genetic engineering, cloning, hybrid technology, health and food technologies, space travel, audio-visual technology, among others. These evidences are indications of the growth of scientific knowledge. Accordingly, this paper raises the question of what is responsible for the growth of scientific knowledge. Inherent in this question is the pool of diverse conceptions of what (...) the nature and method of science is. Consequently, some significant contours in the construct of the problem of demarcation will be imported into this discourse as a means of assembling some pivotal conceptions of the growth of scientific knowledge. With this, the paper aims to consider Karl Popper’s fundamental conception of the growth of scientific knowledge and its associated criticisms, and from it, attempt to respond to the question of what is responsible for the growth of scientific knowledge. This will help to eliminate the confusion and complications surrounding the growth of scientific knowledge. (shrink)

Frank Jackson’s knowledge argument (KA) aims to prove, by means of a thought experiment concerning the hypothetical scientist Mary, that conscious experiences have non-physical properties, called qualia. Mary has complete scientific knowledge of colours and colour vision without having had any colour experience. The central intuition in the KA is that, by seeing colours, Mary will learn what it is like to have colour experiences. Therefore, her scientific knowledge is incomplete, and conscious experiences have qualia. (...) In this paper I consider an objection to the KA raised by Daniel Dennett. He maintains that the KA is vitiated by Jackson’s account of Mary’s scientific knowledge. While endorsing this criticism, I will defend the plausibility and relevance of the type of strategy involved in the KA by offering an account of Mary’s scientific knowledge. This account involves formulating a reasonable and not immediately false version of the physicalist thesis with regard to colour experiences. Whether this version of the KA is successful against this type of physicalism is not investigated here. (shrink)

REVIEW (1): "Jeff Kochan’s book offers both an original reading of Martin Heidegger’s early writings on science and a powerful defense of the sociology of scientific knowledge (SSK) research program. Science as Social Existence weaves together a compelling argument for the thesis that SSK and Heidegger’s existential phenomenology should be thought of as mutually supporting research programs." (Julian Kiverstein, in Isis) ---- REVIEW (2): "I cannot in the space of this review do justice to the richness and range (...) of Kochan's discussion [...]. There is a great deal in this foundational portion of Kochan's discussion that I find tremendously interesting and engaging [...]." (David R. Cerbone, in Studies in History and Philosophy of Science) ---- REVIEW (3): "Science as Social Existence will be of interest not only to Heidegger scholars but to anyone engaged in science and technology studies. [...] This is an informative and original book. Kochan should be praised for his clear, pleasant-to-read prose." (Michael Butler, in CHOICE). (shrink)

This thesis study is about the leading philosophers of philosophy of science of the twentieth century Karl Popper and Thomas Kuhn and their asserted views about science and scientific knowledge and the method, standard and limit of science. Popper who emphasises the deductive method of science and its standard which should be falsifiable indicates that scientific knowledge should have a testable and falsifiable pattern. Kuhn, on the other hand, discusses the standard of scientificity connected to the (...) existing paradigm and its emerging problem solving in other words he accepts it as a "puzzle solving activity" and terminatively associates scientificity with sociological factors. Accordingly, in this thesis study by taking into consideration Popper and Kuhn's differences of opinion aimed at science and its knowledge, the arguments of development and scientific progress within the frame of their own terminology is being evaluated. Then, Popper and Kuhn's thoughts considering the standards of science and the arguments about progress and development of scientific knowledge is being transferred in a comparable and analytical manner. As a result it is advocated that Popper and Kuhn accept the existence of the change of scientific knowledge based on scientific progress and development and that this change is a change of opinion which is continuing nonstop. (shrink)

This paper comprehensively examines Antoine Henri Becquerel’s discovery of radioactivity in 1896, a groundbreaking scientific advancement often viewed through serendipity. This case study explores the typologies of serendipity and investigates the conditions that foster its occurrence. A detailed study of Becquerel’s investigations reveals that his discovery aligns with a Walpolian type of serendipity, characterized by true serendipity heavily influenced by unforeseen experimental results. This paper emphasizes the role of bisociation, a cognitive process associating previously disconnected concepts, in Becquerel’s discovery, (...) challenging the view that his discovery was merely a chance event. Instead, it argues that Becquerel’s discovery represents an intricate interplay of logic and chance, exemplifying the Walpolian type of serendipity. Moreover, by examining Becquerel’s experimental design, results, and innovative approach, this paper illustrates that his discovery adheres to the fundamental aspects of the scientific method, albeit executed in a non-linear and iterative manner. The process and context of Becquerel’s discovery provide valuable insights into scientific knowledge inception, progression, and definition, underscoring the intertwined roles of serendipity and scientific inquiry in advancing science. (shrink)

In this paper we propose an informal exposition of the structure approach in the philosophy of science. Scientific knowledge is here considered as a collection of scientific theories. Each scientific theory has logico-linguistic, model-representing, pragmatic-procedural, and problem-heuristical subsystems and a subsystem of ties. The pivotal methodological concept for the exact description of these subsystems is the named set. We also outline the possibility of applying the structure-nominative approach to certain problems in the philosophy of science.

This volume comprises original articles by leading authors – from philosophy as well as sociology – in the debate around relativism in the sociology of (scientific) knowledge. Its aim has been to bring together several threads from the relevant disciplines and to cover the discussion from historical and systematic points of view. Among the contributors are Maria Baghramian, Barry Barnes, Martin Endreß, Hubert Knoblauch, Richard Schantz and Harvey Siegel.

I argue in this paper that Locke and contemporary Lockeans underestimate the problems involved in their frequent, implicit assumption that when we apply the proviso we use the latest scientific knowledge of natural resources, technology, and the economy’s operations. Problematic for these theories is that much of the pertinent knowledge used is obtained through particular persons’ labor. If the knowledge obtained through individuals’ labor must be made available to everyone and if particular persons’ new knowledge (...) affects the proviso’s proper application, then some end up without freedom to pursue their own ends and some find their freedom subject to others’ arbitrary will. (shrink)

Arguments pro and contra convergent realism – underdetermination of theory by observational evidence and pessimistic meta-induction from past falsity – are considered. It is argued that, to meet the counter-arguments challenge, convergent realism should be considerably changed with a help of modification of the propositions from this meta-programme “hard core” or “protecting belt”. Two well-known convergent realism rivals – “entity realism” of Nancy Cartwright and Ian Hacking and John Worrall’s “structural realism” – are considered. Entity realism’s main drawback is fundamental (...) laws underestimation. As for structural realism, its limitation of theoretical propositions by pure structural ones is ineffective. One always can transform propositions about objects into propositions about structures and vice versa. Both conceptions are kinds of “metaphysical revisionism” that tries to reformulate the good old convergent realism propositions using more decent language and applying ad hoc modifications of the solutions first obtained within the anti-realist epistemological meta-programmes. It is stated that to overcome the troubles of convergent realism one has to turn from classical or “metaphysical” realism to nonclassical or “internal” one and to coherent theory of truth. Internal realism has no troubles in solving the problem of empirically-equivalent theoretical descriptions and historical meta-induction problem, but gets the problem of scientific knowledge objectivity instead. Where does this objectivity come from? One of the answers is proposed by the scientific knowledge growth model elaborated by Rinat Nugayev and by Peter Galison. Each paradigm is a local viewpoint determined by the peculiarities of a culture into which its creator . was submerged. However, the meeting of the different paradigms leads to their interaction; as a result, the crossbred theoretical objects are constructed. Through these systems the infiltration of one paradigm on the other’s domain takes place. After the old paradigms’ grinding the new ones emerge that reconcile to each other much better than the old ones. Scientific theories reconcile results in elimination of many contingent details. In the process of competition more universal components survive. It is demonstrated that the process of objective knowledge genesis takes place in modern superstring theory too. The list of its drawbacks is rather long; it is clear that the theory cannot pretend on the role of the Theory of Everything. Nevertheless the process of argumentation pro and contra convergent realism – underdetermination of theory by observational evidence and pessimistic meta-induction from past falsity – are considered. It is argued that, to meet the counter-arguments challenge, convergent realism should be considerably changed with a help of modification of the propositions from this meta-programme “hard core” or “protecting belt”. It is stated that to overcome the troubles of convergent realism one has to turn from classical or “metaphysic” of quantum field theory and general relativity interpenetration have already begun. (shrink)

This is a translation, made by myself, of the paper to be published in Portuguese in the journal Discurso, 2020, in honour of the late professor Oswaldo Porchat. I discuss what Aristotle was trying to encode when he said that the object of scientific knowledge is necessary, or that what we know (scientifically) cannot be otherwise etc. The paper is meant as a continuation of previous papers—orientated towards a book on the Posterior Analytics—and thus does not discuss in (...) much detail key passages, as the very definition of scientific knowledge in APo I.2, or passages from APo I.4 and I.6 (for these, I refer to my previous papers). This paper is mainly focused on Aristotle’s references to his notion of scientific knowledge both in other passages from the APo and in other treatises. I intend to show that there is a progressive, intrinsic relation between the two requirements by which scientific knowledge is defined. It is not true that each of these requirements stems from a different source. The Causal-Explanatory requirements gives Aristotle the general heading. Then, the Necessity Requirement ranges over the explanatory relation between explanans and explanandum and thereby specifies what sort of cause is sctricly required for having scientific knowledge of a given explanandum. Now, Aristotle was also concerned with the necessary truth of the elemental predications that constitute a demonstration. My claim that the Necessity Requirement ranges over the explanatory relation does not ignore that concern, and does not deny it. My claim is that Aristotle’s main focus, and main concern, consists in stressing that the explanatory factor to be captured in scientific knowledge of a given explanandum is such that cannot be otherwise. (shrink)

The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to (...) create new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease. (shrink)

Book review of: Jeff Kochan (2017). Science as Social Existence: Heidegger and the Sociology of Scientific Knowledge (Cambridge UK: Open Book Publishers).

What is scientific progress? On Alexander Bird’s epistemic account of scientific progress, an episode in science is progressive precisely when there is more scientific knowledge at the end of the episode than at the beginning. Using Bird’s epistemic account as a foil, this paper develops an alternative understanding-based account on which an episode in science is progressive precisely when scientists grasp how to correctly explain or predict more aspects of the world at the end of the (...) episode than at the beginning. This account is shown to be superior to the epistemic account by examining cases in which knowledge and understanding come apart. In these cases, it is argued that scientific progress matches increases in scientific understanding rather than accumulations of knowledge. In addition, considerations having to do with minimalist idealizations, pragmatic virtues, and epistemic value all favor this understanding-based account over its epistemic counterpart. (shrink)

Western science claims to provide unique, objective information about the world. This is supported by the observation that peoples across cultures will agree upon a common description of the physical world. Further, the use of scientific instruments and mathematics is claimed to enable the objectification of science. In this work, carried out by reviewing the scientific literature, the above claims are disputed systematically by evaluating the definition of physical reality and the scientific method, showing that empiricism relies (...) ultimately upon the human senses for the evaluation of scientific theories and that measuring instruments cannot replace the human sensory system. Nativist and constructivist theories of human sensory development are reviewed, and it is shown that nativist claims of core conceptual knowledge cannot be supported by the findings in the literature, which shows that perception does not simply arise from a process of maturation. Instead, sensory function requires a long process of learning through interactions with the environment. To more rigorously define physical reality and systematically evaluate the stability of perception, and thus the basis of empiricism, the development of the method of dimension analysis is reviewed. It is shown that this methodology, relied upon for the mathematical analysis of physical quantities, is itself based upon empiricism, and that all of physical reality can be described in terms of the three fundamental dimensions of mass, length and time. Hereafter the sensory modalities that inform us about these three dimensions are systematically evaluated. The following careful analysis of neuronal plasticity in these modalities shows that all the relevant senses acquire from the environment the capacity to apprehend physical reality. It is concluded that physical reality is acquired rather than given innately, and leads to the position that science cannot provide unique results. Rather, those it can provide are sufficient for a particular environmental setting. (shrink)

Wenn Präsident Kennedy nicht erschossen worden wäre, hätte er dann Nordvietnam bombardiert? Das weiß Gott allein. Oder doch nicht? Weiß wenigstens Er, was Kennedy getan hätte? ... Die Jesuiten behaupteten unter anderem, daß viele menschliche Handlungen in dem Sinne frei seien, daß die Ausführenden nicht logisch oder kausal gezwungen seien, sie auszuführen. („Frei“ wird im vorliegenden Aufsatz stets in diesem Sinne verwendet werden.) Wie behält Gott dann die Kontrolle über die menschliche Geschichte? Nicht dadurch, daß Er menschliche Handlungen kausal determiniert, (...) wie die Dominikaner geglaubt zu haben scheinen , sondern indem Er Umstände herbeiführt, von denen Er weiß, daß wir in ihnen freiwillig Seinen Plänen entsprechend handeln werden. (shrink)

Rationale, aims, and objectives: One of the sectors challenged by the COVID-19 pandemic is medical research. COVID-19 originates from a novel coronavirus (SARSCoV- 2) and the scientific community is faced with the daunting task of creating a novel model for this pandemic or, in other words, creating novel science. This paper is the first part of a series of two papers that explore the intricate relationship between the different challenges that have hindered biomedical research and the generation of (...) class='Hi'>scientific knowledge during the COVID-19 pandemic. Methods: During the early stages of the pandemic, research conducted on hydroxychloroquine (HCQ) was chaotic and sparked several heated debates with respect to the scientific methods used and the quality of knowledge generated. Research on HCQ is used as a case study in both papers. The authors explored biomedical databases, peer-reviewed journals, pre-print servers, and media articles to identify relevant literature on HCQ and COVID-19, and examined philosophical perspectives on medical research in the context of this pandemic and previous global health challenges. Results: This paper demonstrates that a lack of prioritization among research questions and therapeutics was responsible for the duplication of clinical trials and the dispersion of precious resources. Study designs, aimed at minimising biases and increasing objectivity, were, instead, the subject of fruitless oppositions. The duplication of research works, combined with poor-quality research, has greatly contributed to slowing down the creation of novel scientific knowledge. Conclusions: The COVID-19 pandemic presented challenges in terms of (1) finding and prioritising relevant research questions and (2) choosing study designs that are appropriate for a time of emergency. (shrink)

In a series of influential articles, George Bealer argues for the autonomy of philosophical knowledge on the basis that philosophically known truths must be necessary truths. The main point of his argument is that the truths investigated by the sciences are contingent truths to be discovered a posteriori by observation, while the truths of philosophy are necessary truths to be discovered a priori by intuition. The project of assimilating philosophy to the sciences is supposed to be rendered illegitimate by (...) the more or less sharp distinction in these characteristic methods and its modal basis. In this article Bealer's particular way of drawing the distinction between philosophy and science is challenged in a novel manner, and thereby philosophical naturalism is further defended. (shrink)

Rationale, aims and objectives: The COVID-19 pandemic has impacted every facet of society, including medical research. This paper is the second part of a series of articles that explore the intricate relationship between the different challenges that have hindered biomedical research and the generation of novel scientific knowledge during the COVID-19 pandemic. In the first part of this series, we demonstrated that, in the context of COVID-19, the scientific community has been faced with numerous challenges with respect (...) to (1) finding and prioritizing relevant research questions and (2) choosing study designs that are appropriate for a time of emergency. Methods: During the early stages of the pandemic, research conducted on hydroxychloroquine (HCQ) sparked several heated debates with respect to the scientific methods used and the quality of knowledge generated. Research on HCQ is used as a case study in both papers. The authors explored biomedical databases, peerreviewed journals, pre-print servers and media articles to identify relevant literature on HCQ and COVID-19, and examined philosophical perspectives on medical research in the context of this pandemic and previous global health challenges. Results: This second paper demonstrates that a lack of research prioritization and methodological rigour resulted in the generation of fleeting and inconsistent evidence that complicated the development of public health guidelines. The reporting of scientific findings to the scientific community and general public highlighted the difficulty of finding a balance between accuracy and speed. Conclusions: The COVID-19 pandemic presented challenges in terms of (3) evaluating evidence for the purpose of making evidence-based decisions and (4) sharing scientific findings with the rest of the scientific community. This second paper demonstrates that the four challenges outlined in the first and second papers have often compounded each other and have contributed to slowing down the creation of novel scientific knowledge during the COVID-19 pandemic. (shrink)

Bird argues that scientific progress consists in increasing knowledge. Dellsén objects that increasing knowledge is neither necessary nor sufficient for scientific progress, and argues that scientific progress rather consists in increasing understanding. Dellsén also contends that unlike Bird’s view, his view can account for the scientific practices of using idealizations and of choosing simple theories over complex ones. I argue that Dellsén’s criticisms against Bird’s view fail, and that increasing understanding cannot account for (...) class='Hi'>scientific progress, if acceptance, as opposed to belief, is required for scientific understanding. (shrink)

Pythagoras’s number doctrine had a great effect on the development of science. Number – the key to the highest reality, and such approach allowed Pythagoras to transform mathematics from craft into science, which continues implementation of its project of “digitization of being”. Pythagoras's project underwent considerable transformation, but it only means that the plan in knowledge is often far from result.

The National Center for Biomedical Ontology is now in its seventh year. The goals of this National Center for Biomedical Computing are to: create and maintain a repository of biomedical ontologies and terminologies; build tools and web services to enable the use of ontologies and terminologies in clinical and translational research; educate their trainees and the scientific community broadly about biomedical ontology and ontology-based technology and best practices; and collaborate with a variety of groups who develop and use ontologies (...) and terminologies in biomedicine. The centerpiece of the National Center for Biomedical Ontology is a web-based resource known as BioPortal. BioPortal makes available for research in computationally useful forms more than 270 of the world's biomedical ontologies and terminologies, and supports a wide range of web services that enable investigators to use the ontologies to annotate and retrieve data, to generate value sets and special-purpose lexicons, and to perform advanced analytics on a wide range of biomedical data. (shrink)

Through his phenomenological approach, Husserl criticized the situation of science and called it a crisis. He aimed to suggest a way out of this crisis by presenting a philosophical program. However, restoring philosophy to its ancient unifying situation, saving science from this crisis, and giving it a human face, requires, according to critical rationalism, to consider the objectivity and rationality of science. Ignoring these considerations puts science on an incorrect and inconvenient path. These considerations require a revision of Husserl’s essentialism (...) and justificationsim, and placing truth as the aim of science. (shrink)

Dellsén (2017) has recently argued for an understanding-based account of scientific progress, the noetic account, according to which science (or a particular scientific discipline) makes cognitive progress precisely when it increases our understanding of some aspect of the world. Dellsén contrasts this account with Bird’s (2007, 2015) epistemic account, according to which such progress is made precisely when our knowledge of the world is increased or accumulated. In a recent paper, Park (2017) criticizes various aspects of Dellsén’s (...) account and his arguments in favor of the noetic account as against Bird’s epistemic account. This paper responds to Park’s objections. Since a number of Park’s arguments rely on the idea that scientific progress may merely consists in “achieving the means to increase knowledge” (Park 2017: 570), I will start by discussing this “means-end thesis”. (shrink)

A collective understanding that traces a debate between ‘what is science?’ and ‘what is a science about?’ has an extraction to the notion of scientific knowledge. The debate undertakes the pursuit of science that hardly extravagance the dogma of pseudo-science. Scientific conjectures invoke science as an intellectual activity poured by experiences and repetition of the objects that look independent of any idealist views (believes in the consensus of mind-dependence reality). The realistic machinery employs in an empiricist exposition (...) of the objective phenomenon by synchronizing the general method to make observational predictions that cover all the phenomena of the particular entity without any exception. The formation of science encloses several epistemological purviews and a succession of conjectures cum refutation that a newer theorem could reinstate. My attempt is to advocate a holistic plea of scientific conjectures that outruns the restricted regulation of experience or testable hypothesis to render the validity of a chain of logical reasoning (deductive or inductive) of basic scientific statements. The milieu of scientific intensification integrates speculation that loads efficiency towards a new experimental dimension where the reality is not itself objective or observers relative; in fact the observed phenomenon divulges in the constructive progression of preferred methods of falsifiability and uncertainty. (shrink)

A collective understanding that traces a debate between 'what is science?’ and ‘what is a science about?’ has an extraction to the notion of scientific knowledge. The debate undertakes the pursuit of science that hardly extravagance the dogma of pseudo-science. Scientific conjectures invoke science as an intellectual activity poured by experiences and repetition of the objects that look independent of any idealist views (believes in the consensus of mind-dependence reality). The realistic machinery employs in an empiricist exposition (...) of the objective phenomenon by synchronizing the general method to make observational predictions that cover all the phenomena of the particular entity without any exception. The formation of science encloses several epistemological purviews and a succession of conjectures cum refutation that a newer theorem could reinstate. My attempt is to advocate a holistic plea of scientific conjectures that outruns the restricted regulation of experience or testable hypothesis to render the validity of a chain of logical reasoning (deductive or inductive) of basic scientific statements. The milieu of scientific intensification integrates speculation that loads efficiency towards a new experimental dimension where the reality is not itself objective or observers relative; in fact the observed phenomenon divulges in the constructive progression of preferred methods of falsifiability and uncertainty. (shrink)

In this essay, I reflect on the implications of intellectual virtues in scientific endeavor. To this end, I first offer a depiction of scientific endeavor by resorting to the notion of academic attitude, which involves aspects concerning the generation and possession of knowledge. Although there are differences between these activities, they have in common the engagement of diverse intellectual agents (scientists). In this sense, I analyze how intellectual virtues are linked to 1) scientific research tasks, such (...) as theory appraisal, and 2) those tasks of vigilance and intervention in the uses of scientific knowledge. I conclude that intellectual virtues play a leading role in achieving higher quality scientific research and adequate foresight on the uses and impacts of scientific findings. In this order of ideas, I propose an agenda for further inquiries on these matters, highlighting the relevance of reflecting and empirically researching the relationship between intellectual virtues and science, as well as cultivating intellectual virtues in various stages of scientific training. (shrink)

Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced. However, little work has been done to investigate the processes by which these epistemological, metaphysical, and ethical forms of inquiry arise in the course of synthetic biology research. An attempt at this work relying on a particular area of synthetic biology will be the aim of this chapter. I focus on the reengineering (...) of metabolic pathways through the manipulation and construction of small DNA-based devices and systems synthetic biology. Rather than focusing on the engineered products or ethical principles that result, I will investigate the processes by which these arise. As such, the attention will be directed to the activities of practitioners, their manipulation of tools, and the use they make of techniques to construct new metabolic devices. Using a science-in-practice approach, I investigate problems at the intersection of science, philosophy of science, and sociology of science. I consider how practitioners within this area of synthetic biology reconfigure biological understanding and ethical categories through active modelling and manipulation of known functional parts, biological pathways for use in the design of microbial machines to solve problems in medicine, technology, and the environment. We might describe this kind of problem-solving as relying on what Helen Longino referred to as “social cognition” or the type of scientific work done within what Hasok Chang calls “systems of practice”. My aim in this chapter will be to investigate the relationship that holds between systems of practice within metabolic engineering research and social cognition. I will attempt to show how knowledge and normative valuation are generated from this particular network of practitioners. In doing so, I suggest that the social nature of scientific inquiry is ineliminable to both knowledge acquisition and ethical evaluations. (shrink)

With his distinction between the "context of discovery" and the "context of justification", Hans Reichenbach gave the traditional difference between genesis and validity a modern standard formulation. Reichenbach's distinction is one of the well-known ways in which the expression "context" is used in the theory of science. My argument is that Reichenbach's concept is unsuitable and leads to contradictions in the semantic fields of genesis and validity. I would like to demonstrate this by examining the different meanings of Reichenbach's context (...) distinction. My investigation also shows how the difference between genesis and validity precedes Reichenbach's context distinction and indicates approaches for meaningful applications of the concept of context to the phenomena designated by Reichenbach. I will begin by reconstructing the way in which Reichenbach introduces the distinction between discovery and justification as a difference of contexts (I). Drawing on the numerous meanings of the term "context", I will then emphasize some chief characteristics and review, through exemplification, the usage of this term. First of all, I turn to the context of discovery as the nonrational part of all scientific knowledge and show that this meaning cannot be defined consistently (la). For the context of justification, one can distinguish two main cases: the context of justification is either contrasted with the context of discovery, or it forms a unit there with. In the first case, the use of the context term becomes paradoxical, insofar as justification separated from scientific practice does not represent a field of reference which could be specifically contrasted with another field of reference (I b). In the second case, the unifying definitions contradict the contextual meaning of discovery and justification (1 c). In the last section, I point to a useful application of the concept of context which can be found in Reichenbach's argumentation and which refers to the practical conditions of justification(2). (shrink)

Translation and edition (with introduction) of four articles from Hans Kleinpeter: - Nietzsche als Schulreformer, «Blätter für deutsche Erziehung» 14/1912, pp. 99-101; - Der Pragmatismus im Lichte der Machschen Erkenntnislehre, «Wissenschaftliche Rundschau» 20/1912, pp. 405-407; - Die Erkenntnislehre Friedrich Nietzsches, «Wissenschaftliche Rundschau» 3/1912, pp. 5-9; - Ernst Mach und Friedrich Nietzsche, «Neue Freie Presse» 17423 (1913), pp. 31-32. Abstract: Hans Kleinpeter provided a popularization of both Ernst Mach’s thought and the scientific philosophy that forerun the foundation of the Vienna (...) Circle. Between 1912 and 1913 Kleinpeter published the articles that one finds here in their first Italian translation; they concern a comparison between Mach’s epistemology and Nietzsche’s thought, and are thus an original contribution to the reception of the latter’s philosophy. In these texts Kleinpeter anticipates some of the ideas he later presents in his work devoted to the “Phenomenalistic” worldview, whose – according to him – Nietzsche has been one of the main upholders, as much as Mach. (shrink)

This study aimed to determine the levels of pre-service teachers' nature of science (NOS) knowledge, assess their pseudo-scientific beliefs, and examine the relationship between aspects of their NOS knowledge and these beliefs. It also aimed to determine whether NOS knowledge and pseudo-scientific beliefs depended on the discipline and gender. A survey method was conducted in this study. Data were collected from 215 pre-service teachers who are being educated in different fields in a state university. Two (...) different five-point Likert scales were applied. Scale 1, which hasthree factors, measured pseudo-scientific beliefs, while Scale 2, which has seven factors, measured NOS knowledge. As a result, preservice teachers' NOS knowledge was found to be inadequate and their pseudoscientific beliefs were excessive. All factors of Scale 1 were positively correlated with each other, and they were correlated with some components of NOS knowledge. Significant differences were found between disciplines in the analysis of the factors of Scale 2; however, no significant differences were found between genders. (shrink)

Gaston Bachelard is one of the indespensable figures in the history of 20th-century ideas. The broad scope of his work has had a lasting impact in several fields - notable philosophy, architecture and literature.

The interpretive-sensory access theory of self-knowledge claims that we come to know our own minds by turning our capacities for knowing other minds onto ourselves. Peter Carruthers argues that two of the theory’s advantages are empirical adequacy and scientific fruitfulness: it leaves few of the old discoveries unexplained and makes new predictions that provide a framework for new discoveries. A decade has now passed since the theory’s introduction. I review the most important developments during this time period regarding (...) the two criteria: whether the theory’s six main predictions were supported, and whether the theory’s predictions contributed to new empirical studies. I argue that the interpretive-sensory access theory of self-knowledge remains empirically adequate and scientifically fruitful. (shrink)

I discuss two accounts of rational religious faith that have recently been proposed by Peter Rohs and Volker Gerhardt, respectively, and critically explore the relations between (i) faith and knowledge and (ii) faith and hope. I argue that, if faith essentially involves some form of eschatological hope, then a theory of rational faith will have to include an analysis of rational hope.