AI-supported methods for identifying and combating disinformation are progressing in their development and application. However, these methods face a litany of epistemic and ethical challenges. These include (1) robustly defining disinformation, (2) reliably classifying data according to this definition, and (3) navigating ethical risks in the deployment of countermeasures, which involve a mixture of harms and benefits. This paper seeks to expose and offer preliminary analysis of these challenges.

Fears of black-box algorithms are multiplying. Black-box algorithms are said to prevent accountability, make it harder to detect bias and so on. Some fears concern the epistemology of black-box algorithms in medicine and the ethical implications of that epistemology. Durán and Jongsma (2021) have recently sought to allay such fears. While some of their arguments are compelling, we still see reasons for fear.

Many scholars of organizations see social enterprise as a promising approach to advancing social justice but neglect to scrutinize the normative foundations and limitations of this optimism. This article draws on Rawlsian political philosophy to investigate whether and how social enterprises can support social justice. We propose that this perspective assigns organizations a duty to foster institutional capacity, a concept we define and elaborate. We investigate how this duty might apply specifically to social enterprises, given their characteristic features. We theorize (...) six different mechanisms through which social enterprises might successfully discharge this duty. These results affirm the value of conversation between organizational studies and political philosophy and shed new light on debates regarding social enterprise, institutional theory, and several other topics. (shrink)

Ideas for integrating AI into politics are now emerging and advancing at accelerating pace. This chapter highlights a few different varieties and show how they reflect different assumptions about the value of democracy. We cannot make informed decisions about which, if any, proposals to pursue without further reflection on what makes democracy valuable and how current conditions fail to fully realize it. Recent advances in political philosophy provide some guidance but leave important questions open. If AI advances to a state (...) where it can secure superior political outcomes, leading perspectives in political philosophy suggest that democracy may become obsolete. If we find this suggestion troubling, we need to put the case for democracy on stronger foundations. (shrink)

Calls to hold artificial intelligence to account are intensifying. Activists and researchers alike warn of an “accountability gap” or even a “crisis of accountability” in AI. Meanwhile, several prominent scholars maintain that accountability holds the key to governing AI. But usage of the term varies widely in discussions of AI ethics and governance. This chapter begins by disambiguating some different senses and dimensions of accountability, distinguishing it from neighboring concepts, and identifying sources of confusion. It proceeds to explore the idea (...) that AI operates within an accountability gap arising from technical features of AI as well as the social context in which it is deployed. The chapter also evaluates various proposals for closing this gap. I conclude that the role of accountability in AI ethics and governance is vital but also more limited than some suggest. Accountability’s primary job description is to verify compliance with substantive normative principles—once those principles are settled. Theories of accountability cannot ultimately tell us what substantive standards to account for, especially when norms are contested or still emerging. Nonetheless, formal mechanisms of accountability provide a way of diagnosing and discouraging egregious wrongdoing even in the absence of normative agreement. Providing accounts can also be an important first step toward the development of more comprehensive regulatory standards for AI. (shrink)

In July 2020, more than 1000 companies that advertise on social media platforms withdrew their business, citing failures of the platforms (especially Facebook) to address the proliferation of harmful content. The #StopHateForProfit movement invites reflection on an understudied topic: the ethics of boycotting by corporations. Under what conditions is corporate boycotting permissible, required, supererogatory, or forbidden? Although value-driven consumerism has generated significant recent discussion in applied ethics, that discussion has focused almost exclusively on the consumption choices of individuals. As this (...) article underscores, value-driven consumerism by business corporations complicates these issues and invites further examination. We propose principles for the ethics of boycotting by corporations, indicate how these principles relate to different CSR paradigms, and show how these insights can help assess recent instances of corporate boycotting. (shrink)

Intergenerational transfers are a core feature of the practice of private philanthropy. A substantial portion of the resources committed to charitable causes comes from transfers (either during life or at death) that continue to pay out after death. Indeed, much of the power of the charitable foundation lies in its ability to extend the life of an enterprise beyond the mortal existence of its initiating agents. Despite their prevalence, whether and in what way the instruments of intergenerational philanthropy can be (...) justified is controversial. Many have argued that these instruments unfairly privilege the interests of the dead at the expense of the living and unborn. More recently, others have argued that intergenerational charitable transfers comport with the demands of distributive justice and are therefore legitimate. This paper contends that both of these perspectives fail to see the problem for what it is. Intergenerational charitable transfers may indeed promote justice in certain respects, but they do so at the cost of imposing the judgments of the dead onto the living. Respecting the wishes of the past conflicts with an interest in “generational sovereignty.” The paper concludes that properly accounting for this interest in generational sovereignty doesn’t require the abolition of intergenerational philanthropy. But it does tell in favor of a different regulatory orientation than most legal systems currently adopt. (shrink)

Critics of private charity often claim that the well-off should instead assist the disadvantaged through political reform. The present article explores this idea with reference to effective altruism, a powerful new paradigm in the ethics of philanthropy. Effective altruism presses the relatively affluent not only to give generously, but also to subject their practical deliberations to rigorous evaluations of impartiality and cost-effectiveness. The article contends that the movement’s sophisticated methods are not sufficient to overcome the worries of institutionalist critics. At (...) the same time, it shows that a transition from assistance to advocacy faces underappreciated and serious limitations. The measurement-based methods that allow effective altruists to identify promising assistance programs do not carry over well to political reform. In addition, unleashing greater private wealth into politics may exacerbate unequal opportunities for political influence. The article closes with preliminary suggestions for overcoming these concerns and connects them to broader developments in the politics of philanthropy. (shrink)

This chapter defends an overarching ideal of liberal democracy—government for and by the people, where each is considered free and equal—and shows how different conceptions of this ideal lead to different visions of the nonprofit sector. The argument reflects a more fundamental point: that claims about the proper shape and scope of civil society, and certainly the dimensions of nonprofit organizations, are structured by larger political ideals. We cannot understand competing visions of the nonprofit sector without seeing it in relation (...) to the political and social order in which it is supposed to rest. (shrink)

This reply affirms Temkin’s critical perspective on effective altruism but seeks to draw out its constructive implications. It first encourages Temkin to defend the practical urgency of global poverty in the face of doubts about aid effectiveness. It then argues for a more holistic conception of effectiveness to mitigate these doubts. It considers some alternative aid strategies that respond to this broader conception. Finally, it exhorts effective altruists to think more seriously about the reform of global institutions.

Can the existence of a social practice justify practical authority? A medieval debate between hierocrats and caesaropapists may help to illuminate this question. Focusing mainly on Marsilius of Padua, with reference to John of Paris, this article suggests that caesaropapists can be read as developing a 'practice conception' of the structure and scope of ecclesiastical authority. Because it brings the conflict over authority to a new battleground, the practice conception supplies caesaropapists with a source of dialectical leverage over hierocratic doctrine. (...) The paper explores the strengths and limitations of this methodological approach and links it to debates in contemporary political thought. (shrink)

This paper articulates a way to ground a relatively high prior probability for grand explanatory theories apart from an appeal to simplicity. I explore the possibility of enumerating the space of plausible grand theories of the universe by using the explanatory properties of possible views to limit the number of plausible theories. I motivate this alternative grounding by showing that Swinburne’s appeal to simplicity is problematic along several dimensions. I then argue that there are three plausible grand views—theism, atheism, and (...) axiarchism—which satisfy explanatory requirements for plausibility. Other possible views lack the explanatory virtue of these three theories. Consequently, this explanatory grounding provides a way of securing a nontrivial prior probability for theism, atheism, and axiarchism. An important upshot of my approach is that a modest amount of empirical evidence can bear significantly on the posterior probability of grand theories of the universe. (shrink)

From Kant’s point of view, the puzzle about judgments of taste is that they claim to normativity—in Kant’s terms, to intersubjective validity or communicability—but nevertheless have only a subjective basis or “determining ground (Bestimmungsgrund).” The task of §9 of the Critique of Judgment in particular is to delineate an account of aesthetic response that accommodates Kant’s solution to this puzzle. If the aesthetic pleasure “precedes” the judgment—in other words, if the judgment is about the pleasure—then the judgment of taste would (...) be merely private, like other judgments about things that cause us pleasure. So the judgment must precede the pleasure. But “nothing… can be universally communicated except cognition, and representation so far as it belongs to cognition. (V:217) Therefore, the determining ground of the judgment of taste must be “the mental state encountered in the relation of the mental powers of representation to each other insofar as they relate a given cognition to cognition in general.” (V:217) A bit later, he calls this state of mind a “feeling of the free play of the powers of representation in a given representation for a given representation for a cognition in general.” The appeal to ‘cognition in general’ can do what Kant needs it to do only if it conveys the normativity of cognition simpliciter but not its conceptual determinacy. I want to propose that we take ‘cognition in general’ to mean ‘integration into a unified system of empirical cognition.’ If I am successful, it will have the consequence that the basis for the normativity of taste— that is, the expectation that others ought to agree with our judgments-- is the same as the basis for the normativity of cognitive judgments. (shrink)

It is a widespread intuition that the coherence of independent reports provides a powerful reason to believe that the reports are true. Formal results by Huemer, M. 1997. “Probability and Coherence Justification.” Southern Journal of Philosophy 35: 463–72, Olsson, E. 2002. “What is the Problem of Coherence and Truth?” Journal of Philosophy XCIX : 246–72, Olsson, E. 2005. Against Coherence: Truth, Probability, and Justification. Oxford University Press., Bovens, L., and S. Hartmann. 2003. Bayesian Epistemology. Oxford University Press, prove that, under (...) certain conditions, coherence cannot increase the probability of the target claim. These formal results, known as ‘the impossibility theorems’ have been widely discussed in the literature. They are taken to have significant epistemic upshot. In particular, they are taken to show that reports must first individually confirm the target claim before the coherence of multiple reports offers any positive confirmation. In this paper, I dispute this epistemic interpretation. The impossibility theorems are consistent with the idea that the coherence of independent reports provides a powerful reason to believe that the reports are true even if the reports do not individually confirm prior to coherence. Once we see that the formal discoveries do not have this implication, we can recover a model of coherence justification consistent with Bayesianism and these results. This paper, thus, seeks to turn the tide of the negative findings for coherence reasoning by defending coherence as a unique source of confirmation. (shrink)

Here is a puzzle about aesthetic education. In a variety of contexts, we commit significant time, energy, and resources to aesthetic education. We teach (and in many cases publicly subsidize) university courses and degrees that have aesthetic education as their primary aim; we also invest public resources into museums, including enrichment programs that are also designed to afford aesthetic education. It would seem that if our commitment to aesthetic education is rational, then aesthetic appreciation is something that can be done (...) better or worse. However, we also, in a variety of contexts (oddly enough, some of them being the same sorts of contexts that are designed to abet aesthetic education), act as if it is true that there is no disputing taste. We may try to persuade students to come around to particular judgments, but we do not penalize students for judging one way or another. The aim of this paper is to dissolve the apparent puzzle of aesthetic education by clarifying its aims and advancing a conception of it that deemphasizes the role of taste. I claim that, pace “the default view of aesthetic education” (as I shall call it), the primary purpose of aesthetic education is not to educate taste. It is, rather, to facilitate the development of certain perceptual-cognitive capacities so as to enhance aesthetic experience and improve aesthetic appreciation. Thus, I call the view of aesthetic education advanced here “a perceptual-cognitive model”. (shrink)

Evidentialism is one of the most sensible claims of recent philosophy. Yet it is often joined with other theses about the structure of justification and the nature of experience that are dubious. In this paper, I argue that experience is not a basic source of evidence. I contend that for an experience to justify a belief, it must be independently plausible that the experience is reliable based on background information. The paper develops an account of plausibility and examines cases, including (...) differences in expertise, clairvoyance, and social perceptions, to illustrate how background knowledge is necessary for the justification of experiential beliefs. I consider challenges from Bergmann's distinction between learned and unlearned doxastic responses and Lyons's inferential reliabilism. I conclude that these challenges do not succeed; perceptual evidence requires a broader perspective that supports the reliability of the experiential evidence. (shrink)

The coherence of independent reports provides a strong reason to believe that the reports are true. This plausible claim has come under attack from recent work in Bayesian epistemology. This work shows that, under certain probabilistic conditions, coherence cannot increase the probability of the target claim. These theorems are taken to demonstrate that epistemic coherentism is untenable. To date no one has investigated how these results bear on different conceptions of coherence. I investigate this situation using Thagard’s ECHO model of (...) explanatory coherence. Thagard’s ECHO model provides a natural representation of the evidential significance of multiple independent reports. (shrink)

Bas van Fraassen has argued that explanatory reasoning does not provide confirmation for explanatory hypotheses because explanatory reasoning increases information and increasing information does not provide confirmation. We compare this argument with a skeptical argument that one should never add any beliefs because adding beliefs increases information and increasing information does not provide confirmation. We discuss the similarities between these two arguments and identify several problems with van Fraassen’s argument.

Why are we conscious? What does consciousness enable us to do that cannot be done by zombies in the dark? This paper argues that introspective consciousness probably co-evolved as a "spandrel" along with our more useful ability to represent the mental states of other people. The first part of the paper defines and motivates a conception of consciousness as a kind of "double vision" – the perception of how things seem to us as well as what they are – along (...) lines recently explored by Peter Carruthers. The second part explains the basic socioepistemic function of consciousness and suggests an evolutionary pathway to this cognitive capacity that begins with predators and prey. The third part discusses the relevance of these considerations to the traditional problem of other minds. (shrink)

In this paper I defend two closely related claims. The first claim, to which the first section of the paper is devoted, is that for Kant taste is a sort of cognition, that is, a form of awareness of reality for which questions of justification are appropriate. Nevertheless, In our appreciation of natural beauty we are aware of the suitability of appearances for inclusion in a rational system, albeit in a way that is subject to important limitations in comparison with (...) scientific cognition. In the second section of the paper, I will use this reading of Kant’s theory of taste to throw new light on Kant’s account of genius later in the “Critique of Aesthetic Judgment.”. (shrink)

Johann Georg Hamann's "Metakritik über den Purismum der Vernunft" begins with an allusion to Hume's endorsement of Berkeley's rejection of abstract ideas. On the basis of a close examination of the text of the Metakritik, I show that Hamann's overall point is that Kant cannot, or anyway does not, justify the relation of his own linguistic framework to natural language. Thus the Critique cannot meet its own standard for critical self-examination.

Disagreement is common: even informed, intelligent, and generally reasonable people often come to different conclusions when confronted with what seems to be the same evidence. Can the competing conclusions be reasonable? If not, what can we reasonably think about the situation? This volume examines the epistemology of disagreement. Philosophical questions about disagreement arise in various areas, notably politics, ethics, aesthetics, and the philosophy of religion: but this will be the first book focusing on the general epistemic issues arising from informed (...) disagreement. Ten leading philosophers offer specially written essays which together will offer a starting-point for future work on this topic. (shrink)

The problem of biological memory led Russell to propose the existence of mnemic causation, a mechanism by which past experience influences current thought directly, that is, without the need for a material intermediary in the form of a neural "memory trace." Russell appears to have been inspired by German biologist Richard Semon's concept of mnemic homophony, which conveys memory to consciousness on the basis of similarity between current and past circumstances. Semon, however, in no way denied a role for stable (...) neural structures or "engrams" in the memory process. In contrast to Russell, contemporary biologist Rupert Sheldrake provides a viable theory of memory by remaining true to Semon's original idea and expanding it beyond personal memory to the collective memory of species, encompassing not only mental but developmental memory. (shrink)

Suppositions can be introduced in either the indicative or subjunctive mood. The introduction of either type of supposition initiates judgments that may be either qualitative, binary judgments about whether a given proposition is acceptable or quantitative, numerical ones about how acceptable it is. As such, accounts of qualitative/quantitative judgment under indicative/subjunctive supposition have been developed in the literature. We explore these four different types of theories by systematically explicating the relationships canonical representatives of each. Our representative qualitative accounts of indicative (...) and subjunctive supposition are based on the belief change operations provided by AGM revision and KM update respectively; our representative quantitative ones are offered by conditionalization and imaging. This choice is motivated by the familiar approach of understanding supposition as `provisional belief revision' wherein one temporarily treats the supposition as true and forms judgments by making appropriate changes to their other opinions. To compare the numerical judgments recommended by the quantitative theories with the binary ones recommended by the qualitative accounts, we rely on a suitably adapted version of the Lockean thesis. Ultimately, we establish a number of new results that we interpret as vindicating the often-repeated claim that conditionalization is a probabilistic version of revision, while imaging is a probabilistic version of update. (shrink)

When you and I seriously argue over whether a man of seventy is old enough to count as an "old man", it seems that we are appealing neither to our own separate standards of oldness nor to a common standard that is already fixed in the language. Instead, it seems that both of us implicitly invoke an ideal, shared standard that has yet to be agreed upon: the place where we ought to draw the line. As with other normative standards, (...) it is hard to know whether such borderlines exist prior to our coming to agree on where they are. But epistemicists plausibly argue that they must exist whether we ever agree on them or not, as this provides the only logically acceptable response to the sorites paradox. This paper argues that such boundaries do typically exist as hypothetical ideals, but not as determinate features of the present actual world. There is in fact no general solution to the paradox, but attention to practice in resolving vague disagreements shows that its instances can be dealt with separately, as they arise, in many reasonable ways. (shrink)

Prerequisite to memory is a past distinct from present. Because wave evolution is both continuous and time-reversible, the undisturbed quantum system lacks a distinct past and therefore the possibility of memory. With the quantum transition, a reversibly evolving superposition of values yields to an irreversible emergence of definite values in a distinct and transient moment of time. The succession of such moments generates an irretrievable past and thus the possibility of memory. Bohm’s notion of implicate and explicate order provides a (...) conceptual basis for memory as a general feature of nature akin to gravity and electromagnetism. I propose that natural memory is an outcome of the continuity of implicate time in the context of discontinuous explicate time. Among the ramifications of natural memory are that laws of nature can propagate through time much like habits and that personal memory does not require neural information storage. (shrink)

The quantum measurement problem resolves according to the twofold nature of time. Whereas the continuous evolution of the wave function reflects the fundamental nature of time as continuous presence, the collapse of the wave function indicates the subsidiary aspect of time as the projection of instantaneity from the ongoing present. Each instant irreversibly emerges from the reversible temporal continuum implicit in the smoothly propagating wave function. The basis of this emergence is periodic conflict between quantum systems, the definitive resolution of (...) which requires the momentary reduction of each system from the potentially infinite dimensions of configuration space to the three dimensions of classical space at an instant. (shrink)

By deriving the Lorentz transformation from the absolute speed of light, Einstein demonstrated the relativistic variability of space and time, enabling him to explain length contraction and time dilation without recourse to a "luminiferous ether" or preferred frame of reference. He also showed that clocks synchronized at a distance via light signals are not synchronized in a frame of reference differing from that of the clocks. However, by mislabeling the relativity of synchrony the "relativity of simultaneity," Einstein implied that this (...) effect concerns an actual difference in times from one frame to another rather than merely a failure of clock synchronization across frames. As a theory of length contraction and time dilation on the basis of relative motion in the context of the absolute speed of light, special relativity is the definitive interpretation of the Lorentz transformation and the correct explanation of relativistic phenomena. The relativity of simultaneity, as I demonstrate, plays no role in this explanation but instead provides apparent justification for a view of time in which the present moment is frame-dependent. In contrast to its legitimate application, special relativity fails as a theory of time on the basis of the relativity of simultaneity. (shrink)

Conclusion: The present results support adequate psychometric properties in terms of factorial validity, reliability, convergent validity, and measurement invariance for the PHQ-4 in young adults in Hong Kong. The PHQ-4 demonstrated a substantial mediating role in the relationship between meaning in life and SI in the distress group. These findings support clinical relevance for using the PHQ-4 as a brief and valid measure of psychological distress in the Chinese context.

By eliminating the need for an absolute frame of reference or ether, Einstein resolved the problem of the constancy of light-speed in all inertial frames but created a new problem in our understanding of time. The resolution of this problem requires no experimentation but only a careful analysis of special relativity, in particular the relativity of simultaneity. This concept is insufficiently relativistic insofar as Einstein failed to recognize that any given set of events privileges the frame in which the events (...) occur; relative to those events, only the privileged frame yields the correct measurement. Instead of equally valid frames occupying different times, one frame is correct and all others incorrect within a shared present moment. I conclude that (1) time is a succession of universal moments and (2) in the context of flowing time, time dilation requires absolute simultaneity, whereas relative simultaneity predicts a nonexistent phenomenon here dubbed time regression. (shrink)

An atom is characterized mathematically as an evolving superposition of possible values of properties and experimentally as an instantaneous phenomenon with a precise value of a measured property. Likewise, an organism is to itself a flux of experience and to an observer a tangible body in a distinct moment. Whereas the implicit atom is the stream of computation represented by the smoothly propagating wave function, the implicit organism is both the species from which the body individuates and the personal mind (...) its behavior explicates. As with the wave computation that underlies the atom, the substance of the implicit organism is not matter but information. And like projection from a superposition of potential values to a single outcome in a precise and fleeting moment, the organism actualizes only one of the many possible behaviors calculated in the ongoing presence we know as consciousness. (shrink)

Because an unmeasured quantum system consists of information — neither tangible existence nor its complete absence — no property can be assigned a definite value, only a range of likely values should it be measured. The instantaneous transition from information to matter upon measurement establishes a gradient between being and not-being. A quantum system enters a determinate state in a particular moment until this moment is past, at which point the system resumes its default state as an evolving superposition of (...) potential values of properties, neither strictly being nor not-being. Like a “self-organized” chemical system that derives energy from breaking down environmental gradients, a quantum system derives information from breaking down the ontological gradient. An organism is a body in the context of energy and a mind in the context of information. (shrink)

The foundation of irreversible, probabilistic time -- the classical time of conscious observation -- is the reversible and deterministic time of the quantum wave function. The tendency in physics is to regard time in the abstract, a mere parameter devoid of inherent direction, implying that a concept of real time begins with irreversibility. In reality time has no need for irreversibility, and every invocation of time implies becoming or flow. Neither symmetry under time reversal, of which Newton was well aware, (...) nor the absence of an absolute parameter, as in relativity, negates temporal passage. Far from encapsulating time, irreversibility is a secondary property dependent on the emergence of distinct moments from the ceaseless presence charted by the wave function. (shrink)

Though Einstein explained time dilation without recourse to a universal frame of reference, he erred by abolishing universal present moments. Relative simultaneity is insufficiently relativistic insofar as it depends on the absolute equality of reference frames in the measurement of the timing of events. Yet any given set of events privileges the frame in which the events take place. Relative to those events, the privileged frame yields the correct measurement of their timing while all other frames yield an incorrect measurement. (...) Instead of multiple frames occupying multiple times, one frame is correct and all others incorrect within a shared present moment. With the collapse of relative simultaneity, we may regard time as a succession of universal moments. Absolute simultaneity, in turn, explains why an accelerated inertial frame dilates in time rather than regressing to a prior moment relative to non-accelerated frames. In the context of flowing time, absolute simultaneity predicts time dilation while relative simultaneity predicts time regression. Einstein's explanation of time dilation is therefore incomplete. (shrink)

Alex Worsnip's recent book, Fitting Things Together: Coherence and the Demands of Structural Rationality, provides a sustained, wide-ranging defence of dualism.

Bradford Hill (1965) highlighted nine aspects of the complex evidential situation a medical researcher faces when determining whether a causal relation exists between a disease and various conditions associated with it. These aspects are widely cited in the literature on epidemiological inference as justifying an inference to a causal claim, but the epistemological basis of the Hill aspects is not understood. We offer an explanatory coherentist interpretation, explicated by Thagard's ECHO model of explanatory coherence. The ECHO model captures the complexity (...) of epidemiological inference and provides a tractable model for inferring disease causation. We apply this model to three cases: the inference of a causal connection between the Zika virus and birth defects, the classic inference that smoking causes cancer, and John Snow’s inference about the cause of cholera. (shrink)

The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

ABSTRACT: BACKGROUND: The governments and citizens of the developed nations are increasingly called upon to contribute financially to health initiatives outside their borders. Although international development assistance for health has grown rapidly over the last two decades, austerity measures related to the 2008 and 2011 global financial crises may impact negatively on aid expenditures. The competition between national priorities and foreign aid commitments raises important ethical questions for donor nations. This paper aims to foster individual reflection and public debate on (...) donor responsibilities for global health. METHODS: We undertook a critical review of contemporary accounts of justice. We selected theories that: (i) articulate important and widely held moral intuitions; (ii) have had extensive impact on debates about global justice; (iii) represent diverse approaches to moral reasoning; and (iv) present distinct stances on the normative importance of national borders. Due to space limitations we limit the discussion to four frameworks. RESULTS: Consequentialist, relational, human rights, and social contract approaches were considered. Responsibilities to provide international assistance were seen as significant by all four theories and place limits on the scope of acceptable national autonomy. Among the range of potential aid foci, interventions for health enjoyed consistent prominence. The four theories concur that there are important ethical responsibilities to support initiatives to improve the health of the worst off worldwide, but offer different rationales for intervention and suggest different implicit limits on responsibilities. CONCLUSIONS: Despite significant theoretical disagreements, four influential accounts of justice offer important reasons to support many current initiatives to promote global health. Ethical argumentation can complement pragmatic reasons to support global health interventions and provide an important foundation to strengthen collective action. (shrink)

Ted Honderich's theory of consciousness as existence, which he here calls Radical Externalism, starts with a good phenomenological observation: that perceptual experience appears to involve external things being immediately present to us. As P.F. Strawson once observed, when asked to describe my current perceptual state, it is normally enough simply to describe the things around me (Strawson, 1979, p. 97). But in my view that does not make the whole theory plausible.

Drawing on Seamus Heaney and his symbolic reference to a great sea change or tidal wave in epic poem “The Cure at Troy” (1990) – much referred to in these gradually post-pandemic times and indicating that a new chapter is about to begin – and “The City” by Ted Hughes, where a life is read like a poem and in the many depths of the urban space the writer roams “my own darkness”, this paper looks at human resilience in the (...) face of an interrupted COVID reality that has brought a fundamental shift to the way we view the world and our role in society. In our era of a New Normal, the idea that “less is more” is quickly becoming a mantra for our times, a time characterised by a gradual distancing from material hype while we turn to nature for solace and guidance – as importantly advocated by Heaney and Hughes who illuminate our path as we gain a greater understanding of what really matters at the core. We likewise begin to see commonalities between people and cultures, and we open up a space for a greater sense of authenticity. As we are now stepping into the initial stages of 2023, entering a new chapter; have we gained existential insights from the COVID-19 pandemic and will this lead to new beginnings where the written word helps us along the way? (shrink)

Perhaps no one has written more extensively, more deeply, and more insightfully about determinism and freedom than Ted Honderich. His influence and legacy with regard to the problem of free will—or the determinism problem, as he prefers to frame it—looms large. In these comments I would like to focus on three main aspects of Honderich ’s work: his defense of determinism and its consequences for origination and moral responsibility; his concern that the truth of determinism threatens and restricts, but does (...) not eliminate, our life-hopes; and his attack on the traditional justifications for punishment. In many ways, I see my own defense of free will skepticism as the natural successor to Honderich ’s work. There are, however, some small differences between us. My goal in this paper is to clarify our areas of agreement and disagreement and to acknowledge my enormous debt to Ted. If I can also move him toward my own more optimistic brand of free will skepticism that would be great too. (shrink)

Ted Poston's book Reason and Explanation: A Defense of Explanatory Coherentism is a book worthy of careful study. Poston develops and defends an explanationist theory of (epistemic) justification on which justification is a matter of explanatory coherence which in turn is a matter of conservativeness, explanatory power, and simplicity. He argues that his theory is consistent with Bayesianism. He argues, moreover, that his theory is needed as a supplement to Bayesianism. There are seven chapters. I provide a chapter-by-chapter summary along (...) with some substantive concerns. (shrink)