There is a widespread assumption that B-theorists (according to whom there is nothing metaphysically special about the present moment in virtue of which it is present) should interpret the standard tense operators (‘it was the case that’, ‘it will be the case that’) as implicit quantifier-restrictors – so that, for example, an utterance at instant t of the sentence ‘It was the case that there are dinosaurs’ is true just in case there are dinosaurs located at some instant t* earlier (...) than t. However, it is easy to show that this interpretation of the tense operators creates serious problems for B-theorists when combined with certain other relatively uncontroversial B-theoretic assumptions. In this paper, I argue that the best way for B-theorists to respond to these problems is to treat the standard tense operators as redundant when the sentences in their scope are qualitative (i.e. not about any particular individuals). (shrink)

A high level of confidence in the identity of individuals is required to let them die as ordered by an advance directive. Thus, if we are animalists, then we should lack the confidence required to apply lethal advance directives to the cheerfully demented, or so I argue. In short, there is consensus among animalists that the best way to avoid serious objections to their account is to adopt an ontology that denies the existence of brains, hands, tables, chairs, iced-tea, and (...) lemonade. The adoption of such an ontology reduces the justificatory force of commonsense, which is key in arguing that we are animals and that we persist as long as we are biologically alive. With this loss of justification comes the loss of a high level of confidence that Quinn-pre-dementia’s lethal advanced directive applies to Quinn-post-dementia, via identity. If we do not have a high level of confidence that Quinn-pre-dementia’s advanced directive applies to Quinn-post- dementia, then it is not enough (on its own) to let Quinn-post-dementia die. (shrink)

When medical assistance in dying (MAiD) was legalized in Canada in June 2016, the question of allowing decisionally capable persons to make advance requests in anticipation of later incapacity was reserved for further consideration during the mandatory parliamentary review originally scheduled to begin in June 2020 (but since delayed by COVID-19). In its current form the legislation does not permit such requests, since it stipulates that at the time at which the procedure is to be administered the patient must give (...) “express consent” to receiving it. Since express consent presupposes decisional capacity, this requirement rules out administering MAiD to a patient who has lost capacity. Amendments to the legislation passed by Parliament in March 2021 open the door slightly by allowing advance requests by patients after they have been approved for MAiD, if they fear losing capacity before the procedure can be administered. But this provision would apply only to patients whose natural death was deemed to be “reasonably foreseeable”, and would continue to exclude (a) requests made after diagnosis of a “grievous and irremediable medical condition” but in advance of approval for MAiD, and (b) requests made before such a diagnosis. My aim in this paper is twofold: to explore the ethical and legal issues concerning advance requests for MAiD, and to argue for expanding provision for such requests to include both of these further scenarios. (shrink)

The global production of radioactive wastes is expected to increase in the coming years as more countries have resorted to adopting nuclear power to decrease their reliance on fossil-fuel-generated energy. Discoveries of remediation methods that can remove radionuclides from radioactive wastes, including those discharged to the environment, are therefore vital to reduce risks-upon-exposure radionuclides posed to humans and wildlife. Among various remediation approaches available, microbe-mediated radionuclide remediation have limited reviews regarding their advances. This review provides an overview of the sources (...) and existing classification of radioactive wastes, followed by a brief introduction to existing radionuclide remediation (physical, chemical, and electrochemical) approaches. Microbe-mediated radionuclide remediation (bacterial, myco-, and phycoremediation) is then extensively discussed. Bacterial remediation involves biological processes like bioreduction, biosorption, and bioprecipitation. Bioreduction involves the reduction of water-soluble, mobile radionuclides to water-insoluble, immobile lower oxidation states by ferric iron-reducing, sulfate-reducing, and certain extremophilic bacteria, and in situ remediation has become possible by adding electron donors to contaminated waters to enrich indigenous iron- and sulfate-reducing bacteria populations. In biosorption, radionuclides are associated with functional groups on the microbial cell surface, followed by getting reduced to immobilized forms or precipitated intracellularly or extracellularly. Myco- and phycoremediation often involve processes like biosorption and bioaccumulation, where the former is influenced by pH and cell concentration. A Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis on microbial remediation is also performed. It is suggested that two research directions: genetic engineering of radiation-resistant microorganisms and co-application of microbe-mediated remediation with other remediation methods could potentially result in the discovery of in situ or ex situ microbe-involving radioactive waste remediation applications with high practicability. Finally, a comparison between the strengths and weaknesses of each approach is provided. (shrink)

In this commentary, I critique three aspects of Emily Walsh's proposal to reduce the moral and legal weight of advance directives: (1) the ambiguity of its initial thesis, (2) its views about the ethics and legality of clinical practice, and (3) its interpretation and application of Ronald Dworkin’s account of advance directives and L.A. Paul's view on transformative experience. I also consider what Walsh’s proposal would mean for people facing the prospect of dementia. I conclude that our reasons to honor (...) many advance directives survive the move to a transformative experience framework. (shrink)

This paper takes a novel approach to the active bioethical debate over whether advance medical directives have moral authority in dementia cases. Many have assumed that advance directives would lack moral authority if dementia truly produced a complete discontinuity in personal identity, such that the predementia individual is a separate individual from the postdementia individual. I argue that even if dementia were to undermine personal identity, the continuity of the body and the predementia individual’s rights over that body can support (...) the moral authority of advance directives. I propose that the predementia individual retains posthumous rights over her body that she acquired through historical embodiment in that body, and further argue that claims grounded in historical embodiment can sometimes override or exclude moral claims grounded in current embodiment. I close by considering how advance directives grounded in historical embodiment might be employed in practice and what they would and would not justify. (shrink)

The conventional wisdom about advance care planning holds that the normative force of my prior wishes is simply that they are mine. It is their connection to me that matters. This paper challenges conventional thinking. I propose that the normative force of prior wishes does not depend exclusively on personal identity. Instead, it sometimes depends on a special relationship that exists between a prior, capacitated person and a now incapacitated person. I consider what normative guidance governs persons who stand in (...) a special relationship, and contrast these with the standard model of respect for autonomy. My conclusion is that advance care planning for individuals who have lost decision-making capacity should incorporate the virtues of prudence and integrity, even when one and the same person ceases to exist, and respect for personal autonomy is no longer relevant. (shrink)

The fourth amendment to the German Medicinal Products Act (Arzneimittelgesetz) states that nontherapeutic research in incompetent populations is permissible under the condition that potential research participants expressly declare their wish to participate in scientific research in an advance research directive. This article explores the implementation of advance research directives in Germany against the background of the international legal and ethical framework for biomedical research. In particular, it addresses a practical problem that arises from the disclosure requirement for advance research directives. (...) We show that, if the disclosure standard for advance research directives is set at a token level, nontherapeutic research in incompetent populations becomes practically impossible. To resolve this issue, we suggest the disclosure standard be set at a type level. (shrink)

Drawing on the literature on the support of small businesses and case studies, this article advances the case for the support of African immigrant-owned businesses in South Africa which is currently neglected. In the past justification for the institution of support policies in favour of small businesses was predominantly based on the fact that they disproportionately encountered more obstacles than their larger counterparts. Shying away from the traditional “business focus” justification for the support of small business, this study advances an (...) “owner focus” justification - one that is based on the unique needs of the owner, rather than that of the business itself. Following similar logic, given that most immigrants start small businesses as a means of survival in their host countries, this study advances an even more compelling reason why immigrant-owned businesses should be supported. Acknowledging the role that a supported small business sector in general and immigrant-owned business, in particular, can play in the economy and taking steps to strengthen this sector would be in the right direction for the South Africa government. (shrink)

Hastings Center Report, Volume 52, Issue 1, Page 32-41, January/February 2022.

Until recently, experimental philosophy has been associated with the questionnaire-based study of intuitions; however, experimental philosophers now adapt a wide range of empirical methods for new philosophical purposes. New methods include paradigms for behavioural experiments from across the social sciences as well as computational methods from the digital humanities that can process large bodies of text and evidence. This book offers an accessible overview of these exciting innovations. The volume brings together established and emerging research leaders from several areas of (...) experimental philosophy to explore how new empirical methods can contribute to philosophical debates. Each chapter presents one or several methods new to experimental philosophy, demonstrating their application in a key area of philosophy and discussing their strengths and limitations. Methods covered include eye tracking, virtual reality technology, neuroimaging, statistical learning, and experimental economics as well as corpus linguistics, visualisation techniques and data and text mining. The volume explores their use in moral philosophy and moral psychology, epistemology, philosophy of science, metaphysics, philosophy of language, philosophy of mind and the history of ideas. Methodological Advances in Experimental Philosophy is essential reading for undergraduates, graduate students and researchers working in experimental philosophy. (shrink)

Abstract: The integration of Artificial Intelligence (AI) into medical imaging represents a transformative shift in healthcare, offering significant improvements in diagnostic accuracy, efficiency, and patient outcomes. This paper explores the application of AI technologies in the analysis of medical images, focusing on techniques such as convolutional neural networks (CNNs) and deep learning models. We discuss how these technologies are applied to various imaging modalities, including X-rays, MRIs, and CT scans, to enhance disease detection, image segmentation, and diagnostic support. Additionally, the (...) paper addresses the challenges faced in AI-driven medical imaging, including data quality, model interpretability, and ethical considerations. By examining recent advancements and real-world case studies, this paper provides insights into the current state of AI in medical imaging and its potential future directions. The findings highlight the ongoing evolution of AI technologies and their crucial role in advancing medical diagnostics and treatment strategies. (shrink)

Advance directives are intended to extend patient autonomy by enabling patients to prospectively direct the care of their future incapacitated selves. There has been much discussion about issues such as whether the future incompetent self is identical to the agent who issues the advance directives or whether advance directives can legitimately secure patient autonomy. However, there is another important question to ask: to what extent and in what conditions is it ethically appropriate for one to limit the liberty or agency (...) of one’s future incompetent self by issuing an advance directive? -/- In this paper, I use a virtue-ethical approach to explore this question, focusing on the case of an advance directive for the future self with moderate dementia. First, I examine virtuous attitudes with regard to autonomy and argue that one can manifest vices or ethically undesirable character traits in trying to intervene in the future self’s life. In particular, I argue that this case can manifest vices such as disdainfulness, intellectual arrogance, and self-dictatorship, which is the vice of trying to control one’s life to an excessive degree, and that a self-dictator fails to give due moral consideration to the future self’s liberty or agency. I then introduce the Daoist idea of wu-wei, which recommends embracement of what happens in one’s life, as one of the possible remedies for the overemphasis on the value of autonomy and control. (shrink)

I present an internal problem for David Lewis’s genuine modal realism. My aim is to show that his analysis of modality is inconsistent with his metaphysics. I consider several ways of modifying the Lewisian analysis of modality, but argue that none are successful. I argue that the problem also affects theories related to genuine modal realism, including the stage theory of persistence and modal fictionalism.

Advance directives typically have two defects. First, most advance directives fail to enable people to effectively avoid unwanted medical intervention. Second, most of them have the potential of ending your life in ways you never intended, years before you had to die.

This article presents information about facades, their thermal insulating role in buildings in Albania. The façade in construction is one of the necessary factors to ensure a longer life of the buildings and indoor thermal comfort. Façade systems are composed of different materials, which provide a protective effect during the life of the building. The article will focus on the characteristic materials used in Albania for the construction of facades and the main materials used from the year 2000 up to (...) today. The article will be informative, statistical, and comparative in order to draw conclusions. Nowadays building facades are again becoming one of the main subjects of discussion, undoubtedly due to the increasing importance of the building envelope in relation to energy consumption. In the 90s, minimal attention was paid to the efficiency and quality of facades; everything was done strictly in relation to residency requirements. But, during this last decade, Albania experienced a construction boom, with a series of good new buildings, which are accompanied by progress in the architectural style and in the techniques of building materials usage. However, the advantages of façade systems in construction are not only to make the building long-lasting. The function of facades always undergoes changes and advances over time, in terms of their impact on the temperature fluctuations inside the building or energy storage. (shrink)

In this chapter we explain what experimental philosophy of science is, how it relates to the philosophy of science, and STS more broadly, and what sorts of contributions is can make to ongoing research in the philosophy of science.

This book aims to provide a comprehensive analysis of Advanced Persistent Threats (APTs), including their characteristics, origins, methods, consequences, and defense strategies, with a focus on detecting these threats. It explores the concept of advanced persistent threats in the context of cyber security and cyber warfare. APTs represent one of the most insidious and challenging forms of cyber threats, characterized by their sophistication, persistence, and targeted nature. The paper examines the origins, characteristics and methods used by APT actors. (...) It also explores the complexities associated with APT detection, analyzing the evolving tactics used by threat actors and the corresponding advances in detection methodologies. It highlights the importance of a multi-faceted approach that integrates technological innovations with proactive defense strategies to effectively identify and mitigate APT. (shrink)

Abstract: Early detection of breast cancer plays a pivotal role in improving patient prognosis and reducing mortality rates. Recent technological advancements have significantly enhanced the accuracy and effectiveness of breast cancer screening methods. This paper explores the latest innovations in early detection, including the evolution of digital mammography, the impact of 3D mammography (tomosynthesis), and the use of advanced imaging techniques such as molecular imaging and MRI. Furthermore, the integration of artificial intelligence (AI) in diagnostic tools is discussed, highlighting (...) how machine learning algorithms are refining imaging analyses and reducing diagnostic errors. Advances in genetic screening, liquid biopsies, and biomarkers are also examined, showcasing their potential in identifying high-risk individuals and enabling personalized treatment plans. This paper provides insights into the future of breast cancer detection, outlining both the opportunities and challenges that lie ahead in adopting these innovative technologies to improve patient outcomes. (shrink)

There is a need recognized by the National Institute of Dental & Craniofacial Research and the National Cancer Institute to advance basic, translational and clinical saliva research. The goal of the Salivaomics Knowledge Base (SKB) is to create a data management system and web resource constructed to support human salivaomics research. To maximize the utility of the SKB for retrieval, integration and analysis of data, we have developed the Saliva Ontology and SDxMart. This article reviews the informatics advances in saliva (...) diagnostics made possible by the Saliva Ontology and SDxMart. (shrink)

This fifth volume on Advances and Applications of DSmT for Information Fusion collects theoretical and applied contributions of researchers working in different fields of applications and in mathematics, and is available in open-access. The collected contributions of this volume have either been published or presented after disseminating the fourth volume in 2015 in international conferences, seminars, workshops and journals, or they are new. The contributions of each part of this volume are chronologically ordered. First Part of this book presents some (...) theoretical advances on DSmT, dealing mainly with modified Proportional Conflict Redistribution Rules (PCR) of combination with degree of intersection, coarsening techniques, interval calculus for PCR thanks to set inversion via interval analysis (SIVIA), rough set classifiers, canonical decomposition of dichotomous belief functions, fast PCR fusion, fast inter-criteria analysis with PCR, and improved PCR5 and PCR6 rules preserving the (quasi-)neutrality of (quasi-)vacuous belief assignment in the fusion of sources of evidence with their Matlab codes. Because more applications of DSmT have emerged in the past years since the apparition of the fourth book of DSmT in 2015, the second part of this volume is about selected applications of DSmT mainly in building change detection, object recognition, quality of data association in tracking, perception in robotics, risk assessment for torrent protection and multi-criteria decision-making, multi-modal image fusion, coarsening techniques, recommender system, levee characterization and assessment, human heading perception, trust assessment, robotics, biometrics, failure detection, GPS systems, inter-criteria analysis, group decision, human activity recognition, storm prediction, data association for autonomous vehicles, identification of maritime vessels, fusion of support vector machines (SVM), Silx-Furtif RUST code library for information fusion including PCR rules, and network for ship classification. Finally, the third part presents interesting contributions related to belief functions in general published or presented along the years since 2015. These contributions are related with decision-making under uncertainty, belief approximations, probability transformations, new distances between belief functions, non-classical multi-criteria decision-making problems with belief functions, generalization of Bayes theorem, image processing, data association, entropy and cross-entropy measures, fuzzy evidence numbers, negator of belief mass, human activity recognition, information fusion for breast cancer therapy, imbalanced data classification, and hybrid techniques mixing deep learning with belief functions as well. (shrink)

The third volume of “Advancing Uncertain Combinatorics through Graphization, Hyperization, and Uncertainization: Fuzzy, Neutrosophic, Soft, Rough, and Beyond” presents an in-depth exploration of the cutting-edge developments in uncertain combinatorics and set theory. This comprehensive collection highlights innovative methodologies such as graphization, hyperization, and uncertainization, which enhance combinatorics by incorporating foundational concepts from fuzzy, neutrosophic, soft, and rough set theories. These advancements open new mathematical horizons, offering novel approaches to managing uncertainty within complex systems. Combinatorics, a discipline focused on counting, arrangement, (...) and structure, often faces challenges when uncertainty is present. Set theory, which underpins combinatorial problems, has evolved to tackle these challenges. The introduction of fuzzy and neutrosophic sets has expanded the toolkit for modeling uncertainty by incorporating elements of truth, indeterminacy, and falsehood into decision-making processes. These innovations seamlessly intersect with graph theory, providing new ways to represent uncertain structures through "graphized" forms such as hypergraphs and superhypergraphs. This volume also introduces advanced concepts like Neutrosophic Oversets, Undersets, and Offsets, which push the boundaries of classical graph theory and offer deeper insights into the mathematical and practical challenges posed by real-world systems. By blending combinatorics, set theory, and graph theory, the authors have created a robust framework for addressing uncertainty in both mathematical systems and their real-world applications. This foundation sets the stage for future breakthroughs in combinatorics, set theory, and related fields. Each chapter in this volume contributes both theoretical foundations and practical applications, demonstrating the power of integrating graph theory, set theory, and uncertainty models. The new ideas, algorithms, and mathematical tools presented here will drive the future of combinatorial research and its applications in uncertain environments. In the first chapter, “Introduction to Upside-Down Logic: Its Deep Relation to Neutrosophic Logic and Applications”, the authors present Upside-Down Logic, a novel logical framework that systematically transforms truths into falsehoods and vice versa, based on contextual shifts. Introduced by F. Smarandache, this paper provides a mathematical definition of Upside-Down Logic, including applications related to the Japanese language. The chapter also introduces Contextual Upside-Down Logic, an extension that adjusts logical connectives alongside flipped truth values, as well as Indeterm-Upside-Down Logic and Certain Upside-Down Logic to address indeterminacy. A simple algorithm is also proposed to demonstrate the computational aspects of this logic. In the second chapter, “Local-Neutrosophic Logic and Local-Neutrosophic Sets: Incorporating Locality with Applications”, the authors introduce Local-Neutrosophic Logic and Local-Neutrosophic Sets, which integrate the concept of locality into Neutrosophic Logic. By defining locality as the influence of immediate surroundings on an object or system, this chapter explores how it affects indeterminacy in real-world problems. The paper also examines potential applications and provides mathematical definitions for these new concepts. The third chapter, “A Review of Fuzzy and Neutrosophic Offsets: Connections to Some Set Concepts and Normalization Function”, extends the concept of offsets in uncertain set-theoretic frameworks, such as Fuzzy Sets, Neutrosophic Sets, and Plithogenic Sets. This chapter introduces several advanced types of offsets, including Nonstationary Fuzzy Offset, Multi-valued Plithogenic Offset, and Subset-valued Neutrosophic Offset, offering deeper insights into handling uncertainty in mathematical models. In the fourth chapter, “Review of Plithogenic Directed, Mixed, Bidirected, and Pangene OffGraph”, the authors build upon Plithogenic Graphs to propose extensions such as Plithogenic Directed OffGraph, Plithogenic BiDirected OffGraph, and Plithogenic Mixed OffGraph. These new concepts, including the Plithogenic Pangene OffGraph, are explored in detail, with a focus on their mathematical properties and potential applications in uncertain graph theory. The fifth chapter, “Short Note on Neutrosophic Closure Matroids”, explores the extension of matroid concepts into Neutrosophic and Turiyam Neutrosophic set theories, introducing Neutrosophic closure matroids. This concept integrates uncertainty, indeterminacy, and liberal states into matroid theory, enhancing its applicability in optimization and combinatorial problems. In the sixth chapter, “Some Graph Parameters for Superhypertree-width and Neutrosophic Tree-width”, the authors discuss graph parameters such as Superhypertree-width and Neutrosophic tree-width. These parameters play a crucial role in the study of graph characteristics, particularly in algorithms and real-world applications. The chapter explores the generalization of hypergraphs to SuperHyperGraphs and examines how these concepts extend tree-width parameters within the context of Neutrosophic logic. (shrink)

The debate on whether and why misinformation is bad primarily focuses on the spread of false beliefs as its main harm. From the assumption that misinformation primarily causes harm through the spread of false beliefs as a starting point, it has been contended that the problem of misinformation has been exaggerated. Its tendency to generate false beliefs appears to be limited. However, the near-exclusive focus on whether or not misinformation dupes people with false beliefs neglects other epistemic harms associated with (...) it. Specifically, I show that misinformation also causes trouble for the epistemic goods of truth attainment, intellectual autonomy and debate pluriformity. Moreover, for each of these goods, I argue that emphasizing error-avoidance exacerbates, rather than mitigates, the harms caused by misinformation. These oversights and dilemmas show that prioritizing error-avoidance in the fight against misinformation is not a neutral default policy or necessarily a net positive. A shift in focus away from the spread of false beliefs as the main harm of misinformation is needed to better understand and counter its negative effects. (shrink)

What follows is a dialogue between Maurice and Orensanz, in which they will discuss some key topics stemming from Bunge’s oeuvre. The objective of this dialogue is to advance the metascientific program even further. The main points that will be discussed can be presented as a series of questions: Is it possible to prove that the external world exists? What is matter? Is the part-whole relation transitive? What is the difference between systems and assortments? Do fictional objects have a function (...) in ontology? Although those are the main topics, several other points will be discussed throughout this exchange. (shrink)

This paper delves into the integration of optimization techniques within ABKS to enhance search efficiency and data security in cloud storage environments. We explore various optimization strategies, such as index compression, query processing enhancement, and encryption optimization, which aim to reduce computational overhead while maintaining robust security measures. Through a comprehensive analysis, the paper illustrates how these techniques can significantly improve the performance of cloud storage systems, ensuring both security and usability. Experimental results demonstrate that optimized ABKS not only accelerates (...) search queries but also reduces storage costs, making it a viable solution for modern cloud storage challenges. Future research directions include exploring advanced machine learning algorithms for predictive search optimizations and further improving the resilience of ABKS against emerging security threats. (shrink)

The first part of a symposium devoted to Alex Broadbent's essay titled ‘Prediction, Understanding and Medicine’, this article notes the under-development of a variety of issues in the philosophy of medicine that transcend bioethics and the long-standing debates about the nature of health/illness and of evidence-based medicine. It also indicates the importance of drawing on non-Western, and particularly African, traditions in addressing these largely metaphysical and epistemological matters.

After 41 years from the approval of the first living will law in 1976 in California, on December 22nd 2017 the bill on “Rules on in- formed consent and advance directives” has been approved in Italy. The applicability of the law highlights a lack of a univocal methodol- ogy regarding the recovery process of the patient’s subjective dimension under a testamentary will; so, it seemed useful to highlight the passages that occur between the drafting and the use of an advance (...) directive in an existential phenomenological prospective. Is the individual who freely drafts an A.D., choosing to decide now for the future, the same per- son for which the provisions were outlined? The goal of this paper is to offer an ethical reading of the ontological issue that illness can raises. (shrink)

The second volume of “Advancing Uncertain Combinatorics through Graphization, Hyperization, and Uncertainization: Fuzzy, Neutrosophic, Soft, Rough, and Beyond” presents a deep exploration of the progress in uncertain combinatorics through innovative methodologies like graphization, hyperization, and uncertainization. This volume integrates foundational concepts from fuzzy, neutrosophic, soft, and rough set theory, among others, to further advance the field. Combinatorics and set theory, two central pillars of mathematics, focus on counting, arrangement, and the study of collections under defined rules. Combinatorics excels in handling (...) uncertainty, while set theory has evolved with concepts such as fuzzy and neutrosophic sets, which enable the modeling of complex real-world uncertainties by addressing truth, indeterminacy, and falsehood. These advancements, when combined with graph theory, give rise to novel forms of uncertain sets in "graphized" structures, including hypergraphs and superhypergraphs. Innovations such as Neutrosophic Oversets, Undersets, and Offsets, as well as the Nonstandard Real Set, build upon traditional graph concepts, pushing both theoretical and practical boundaries. The synthesis of combinatorics, set theory, and graph theory in this volume provides a robust framework for addressing the complexities and uncertainties inherent in both mathematical and real-world systems, paving the way for future research and application. In the first chapter, “A Review of the Hierarchy of Plithogenic, Neutrosophic, and Fuzzy Graphs: Survey and Applications”, the authors investigate the interrelationships among various graph classes, including Plithogenic graphs, and explore other related structures. Graph theory, a fundamental branch of mathematics, focuses on networks of nodes and edges, studying their paths, structures, and properties. A Fuzzy Graph extends this concept by assigning a membership degree between 0 and 1 to each edge and vertex, representing the level of uncertainty. The Turiyam Neutrosophic Graph is introduced as an extension of both Neutrosophic and Fuzzy Graphs, while Plithogenic graphs offer a potent method for managing uncertainty. The second chapter, “Review of Some Superhypergraph Classes: Directed, Bidirected, Soft, and Rough”, examines advanced graph structures such as directed superhypergraphs, bidirected hypergraphs, soft superhypergraphs, and rough superhypergraphs. Classical graph classes include undirected graphs, where edges lack orientation, and directed graphs, where edges have specific directions. Recent innovations, including bidirected graphs, have sparked ongoing research and significant advancements in the field. Soft Sets and their extension to Soft Graphs provide a flexible framework for managing uncertainty, while Rough Sets and Rough Graphs address uncertainty by using lower and upper approximations to handle imprecise data. Hypergraphs generalize traditional graphs by allowing edges, or hyperedges, to connect more than two vertices. Superhypergraphs further extend this by allowing both vertices and edges to represent subsets, facilitating the modeling of hierarchical and group-based relationships. The third chapter, “Survey of Intersection Graphs, Fuzzy Graphs, and Neutrosophic Graphs”, explores the intersection graph models within the realms of Fuzzy Graphs, Intuitionistic Fuzzy Graphs, Neutrosophic Graphs, Turiyam Neutrosophic Graphs, and Plithogenic Graphs. The chapter highlights their mathematical properties and interrelationships, reflecting the growing number of graph classes being developed in these areas. Intersection graphs, such as Unit Square Graphs, Circle Graphs, and Ray Intersection Graphs, are crucial for understanding complex graph structures in uncertain environments. The fourth chapter, “Fundamental Computational Problems and Algorithms for SuperHyperGraphs”, addresses optimization problems within the SuperHypergraph framework, such as the SuperHypergraph Partition Problem, Reachability, and Minimum Spanning SuperHypertree. The chapter also adapts classical problems like the Traveling Salesman Problem and the Chinese Postman Problem to the SuperHypergraph context, exploring how hypergraphs, which allow hyperedges to connect more than two vertices, can be used to solve complex hierarchical and relational problems. The fifth chapter, “A Short Note on the Basic Graph Construction Algorithm for Plithogenic Graphs”, delves into algorithms designed for Plithogenic Graphs and Intuitionistic Plithogenic Graphs, analyzing their complexity and validity. Plithogenic Graphs model multi-valued attributes by incorporating membership and contradiction functions, offering a nuanced representation of complex relationships. The sixth chapter, “Short Note of Bunch Graph in Fuzzy, Neutrosophic, and Plithogenic Graphs”, generalizes traditional graph theory by representing nodes as groups (bunches) rather than individual entities. This approach enables the modeling of both competition and collaboration within a network. The chapter explores various uncertain models of bunch graphs, including Fuzzy Graphs, Neutrosophic Graphs, Turiyam Neutrosophic Graphs, and Plithogenic Graphs. In the seventh chapter, “A Reconsideration of Advanced Concepts in Neutrosophic Graphs: Smart, Zero Divisor, Layered, Weak, Semi, and Chemical Graphs”, the authors extend several fuzzy graph classes to Neutrosophic graphs and analyze their properties. Neutrosophic Graphs, a generalization of fuzzy graphs, incorporate degrees of truth, indeterminacy, and falsity to model uncertainty more effectively. The eighth chapter, “Short Note of Even-Hole-Graph for Uncertain Graph”, focuses on Even-Hole-Free and Meyniel Graphs analyzed within the frameworks of Fuzzy, Neutrosophic, Turiyam Neutrosophic, and Plithogenic Graphs. The study investigates the structure of these graphs, with an emphasis on their implications for uncertainty modeling. The ninth chapter, “Survey of Planar and Outerplanar Graphs in Fuzzy and Neutrosophic Graphs”, explores planar and outerplanar graphs, as well as apex graphs, within the contexts of fuzzy, neutrosophic, Turiyam Neutrosophic, and plithogenic graphs. The chapter examines how these types of graphs are used to model uncertain parameters and relationships in mathematical and real-world systems. The tenth chapter, “General Plithogenic Soft Rough Graphs and Some Related Graph Classes”, introduces and explores new concepts such as Turiyam Neutrosophic Soft Graphs and General Plithogenic Soft Graphs. The chapter also examines models of uncertain graphs, including Fuzzy, Intuitionistic Fuzzy, Neutrosophic, and Plithogenic Graphs, all designed to handle uncertainty in diverse contexts. The eleventh chapter, “Survey of Trees, Forests, and Paths in Fuzzy and Neutrosophic Graphs”, provides a comprehensive study of Trees, Forests, and Paths within the framework of Fuzzy and Neutrosophic Graphs. This chapter focuses on classifying and analyzing graph structures like trees and paths in uncertain environments, contributing to the ongoing development of graph theory in the context of uncertainty. (shrink)

This paper explores the notion of the self as one of the main obstacles in advancing neuroscience. Some folks argue for strict naturalism in order to study the brain objectively. However, in this process of naturalization, we run the risk of losing key components that make up our experience as human beings, namely emotions, ideas, and values. Therefore, I argue for moderate naturalism in an attempt to reconcile with the self. I reference Immanuel Kant’s moral law theory in order to (...) discuss the ethical implications of following a moderate naturalist view of the self in advancing neuroscience. (shrink)

At this juncture, the relevance of the human right to science is undeniable. The right, for a long time, has been a subject matter of deliberation under Article 15 of the International Covenant on Economic, Social and Cultural Rights, 1966 (ICESCR). Most of these deliberations emphasised the need for a concise meaning and scope of the right to science. In the year 2020, the Committee on Economic, Social and Cultural Rights (CESCR) under the ICESCR made two interventions with the objective (...) of defining, advancing and mainstreaming the right to science. The two interventions include General Comment No. 25 on Science and Economic, Social and Cultural Rights, and the Statement on the Coronavirus Disease (COVID-19) Pandemic and Economic, Social and Cultural Rights. This paper concerns the above mentioned statements of the CESCR, in particular, the interpretations and standards being advanced by the Committee. (shrink)

As our experience with this special issue shows, climate change is such a multi-faceted problem that interdisciplinary research is a necessity. This is much more easily said than done. In the course of the publication of this special issue there were many lessons to be learned. First of all we saw how the exchange between our authors allowed them to expand the focus of their respective disciplines. Philosophers considered literature from various fields they would not have touched upon in their (...) usual course of inquiry. Scientists and legal scholars became more sensitive to the normative dimensions and justice-related intricacies involved in their research. This enabled all contributors to open up to different vocabularies and standards of research. At the same time, however, several obstacles to the success of this issue emerged as well. For such an endeavor it is necessary to find researchers who are ready to engage with other disciplines and to take up ideas and comments which at first sight might not seem relevant and out of place from their disciplinary perspective. Due to the special format another challenge was to communicate the interdisciplinary character of this special issue to the reviewers and to put the reviews in context accordingly without risking to diminish the disciplinary quality of contributions. For the guest editors this came with a further challenge. We not only had to become familiar with different disciplinary vocabularies and standards of research but also had to judge the quality and relevance of contributions in the light of our overall aim as well as disciplinary standards of quality. (shrink)

Monkeypox, an infectious disease caused by the Orthopoxvirus, was identified in humans in 1970. It has recently emerged as a global health concern due to outbreaks beyond its endemic regions in Central and West Africa. This review examines the current state of medical treatments for monkeypox as of 2024, focusing on antiviral agents, immunotherapies, and supportive care measures. Monkeypox manifests with symptoms including fever, rash, and lymphadenopathy, with severe cases more common in immunocompromised individuals. Antiviral therapies such as tecovirimat and (...) brincidofovir are central to treatment strategies, with tecovirimat demonstrating efficacy in alleviating symptoms and reducing viral shedding. Emerging treatment strategies involve novel lipid-based formulations and combination therapies that integrate antivirals with immune-modulating agents. Supportive care remains essential, involving analgesics and antibiotics for secondary infections, while the MVA-BN vaccine plays a critical role in prevention. Research emphasizes the need for a deeper understanding of viral pathogenesis and host immune responses to improve therapeutic and preventive measures. Despite significant advancements, challenges remain, including potential antiviral resistance, disparities in healthcare access, and the necessity for enhanced diagnostic and surveillance capabilities. This review highlights the imperative for ongoing research, international collaboration, and investment in healthcare infrastructure to advance the management and prevention of monkeypox and to prepare for future outbreaks. (shrink)

The rapid advancement of artificial (computer) intelligence systems (CIS) has generated a means whereby assistive bionic prosthetics can become both more effective and practical for the patients who rely upon the use of such machines in their daily lives. However, de lege lata remains relatively unspoken as to the legal status of patients whose devices contain self-learning CIS that can interface directly with the peripheral nervous system. As a means to reconcile for this lack of legal foresight, this article approaches (...) the topic of CIS-nervous system interaction and the impacts it may have on the legal definition of “persons” under the law. While other literature of this nature centres upon notions of transhumanism or self-enhancement, the approach herein approached is designed to focus solely upon the legal nature of independent CIS actions when operating alongside human subjects. To this end, it is hoped that further discussion on the topic can be garnered outside of transhumanist discourse to expedite legal consideration for how these emerging relationships ought to be received by law-generating bodies internationally. (shrink)

In this book, we approach different topics related to neutrosophics, such as: Neutrosophic Set, Intuitionistic Fuzzy Set, Inconsistent Intuitionistic Fuzzy Set, Picture Fuzzy Set, Ternary Fuzzy Set, Pythagorean Fuzzy Set, Atanassov’s Intuitionistic Fuzzy Set of second type, Spherical Fuzzy Set, n-HyperSpherical Neutrosophic Set, q-Rung Orthopair Fuzzy Set, truth-membership, indeterminacy-membership, falsehood-nonmembership, Regret Theory, Grey System Theory, Three-Ways Decision, n-Ways Decision, Neutrosophy, Neutrosophication, Neutrosophic Probability, Refined Neutrosophy, Refined Neutrosophication, Nonstandard Analysis; (Theory, NeutroTheory, AntiTheory), S-denying an Axiom, Multispace with Multistructure, and so on.

Narratologists commonly draw a distinction between the story and those things that tell the story- the tellings, as I will call them here. Here is an example intended to highlight that distinction. The Parable of the Sower is a parable found in the New Testament books of Matthew, Mark and Luke, and in the non-canonical Gospel of Thomas. Though the relevant pieces of text in the Gospels are remarkably similar, no two of the four are identical. The verses in Matthew, (...) Mark and Luke, have been translated and paraphrased, along with the rest of the Bible, into literally thousands of different languages and versions, all of which include the The Parable of the Sower. (shrink)

We discuss how analysis of contemporary artworks has shaped philosophical theories about the concept of art, the ontology of art, and artistic media. The rapid expansion, during the contemporary period, of the kinds of things that can count as artworks has prompted a shift toward procedural definitions, which focus on how artworks are selected, and away from definitions that focus exclusively on artworks’ features or effects. Some contemporary artworks challenge the traditional art–ontological dichotomy between physical particulars and repeatable entities whose (...) occurrences are physical particulars. And nontraditional techniques and materials employed in contemporary art violate the boundaries of conventional media, prompting a rethinking of what artistic medium might be. (shrink)

The objective of this article is to try to elucidate Wittgenstein’s ex-travagant thesis that each and every mathematical advancement involves some “semantical mutation”, i.e., some alteration of the very meanings of the terms involved. To do that we will argue in favor of the idea of a “modal incompati-bility” between the concepts involved, as they were prior to the advancement, and what they become after the new result was obtained. We will also argue that the adoption of this thesis profoundly (...) alters the traditional way of con-struing the idea of “progress” in mathematics. (shrink)

The topic of discourse titled “Advancement of Global Peace Building from the Periscope of Kant‟s Philosophy of Perpetual Peace” is centered on the clarion call for the placement of the study of Arts and Humanities at the forefront of human existential candescence. Global peace is a phenomenal thrust in Arts and Humanities, which if jettisoned could affect our existence. Within this frame of conception, Kant‟s Philosophy of perpetual is examined in Arts and Humanities to proffer to solution to man. Kant‟s (...) perpetual peace as an expository and critical adumbration reveals the indispensability of Arts and Humanities in all facets of man‟s endevours. Kant‟s indulgences in the philosophy of perpetual peace was a call for nations and individuals to pursue peace and build on it for existential benefits and global peace. His insistence on “love, virtuous duty to others and respect” where founded on dignity on man. The objective of the work is to reemphasis that within the ambience of Kant‟s philosophy of peace adequate interest into ought to be placed to the study of Arts and Humanities. Contemporaneously, man has experienced terrorism, kidnappings, wars and other forms of conflicts which has impeded peace building and universal harmony. The critical and analytical methods of philosophy as reflected in this work educe that through the instrumentality of Arts and Humanities, advancement of global peace is a possibility through Kant‟s perpetual peace. Man therefore needs and desire peace, build on peace for continuous enjoyment of nature‟s beneficence. (shrink)

We call for a change-of-attitude towards reviews of scientific literature. We begin with an acknowledgement of reviews as pathways for the advancement of our scientific understanding of reality. The significance of the scientific struggle propelling the putting together of pieces of knowledge into parts of a cohesive body of understanding is recognized, and yet undervalued, especially in empirical sciences. Here we propose a nudge, which is prefacing the insights gained in reviewing the literature with: 'Our review reveals' (or an equivalent (...) phrase), that can bring about the desired cultural shift in the practice of science. The resulting elevation of the status of reviews to that of original findings would also bring about the desirable smoothening of the undesirable schism between theorists and experimentalists. (shrink)

Although advance directives are widely believed to be a key way to safeguard the autonomy of incompetent medical patients, significant questions exist about their moral authority. The main philosophical concern involves cases in which an incompetent patient no longer possesses the desires on which her advance directive was based. The question is, does that entail that prior expressions of medical choices are no longer morally binding? I believe that the answer is “yes.” I argue that a patient’s autonomy is not (...) respected by honoring the desires she used to have but no longer does. I also consider and reject the view that honoring an advance directive that reflects the patient’s previous values must be in that patient’s best interests. If that is correct, then advance directives in the kind of case at issue are not morally binding. (shrink)

The Genetic Ranking Optimization Algorithm (GROA) is used to rank phishing content based on multiple features by optimizing the ranking system through iterative selection and weighting. Dynamic weighting further enhances the process by adjusting the weights of features based on their importance in real-time. This hybrid approach enables the model to learn from the data, improving classification over time. The classification system was evaluated using benchmark phishing datasets, and the results demonstrated a significant improvement in detection accuracy and reduced false (...) positives. (shrink)

Worldwide populations are aging with economic development as a result of public health initiatives and advances in therapeutic discoveries. Since 1850, life expectancy has advanced by 1 year for every four. Accompanying this change is the rapid development of anti‐aging science. There are three schools of thought in the field of aging science. One perspective is the life course approach, which considers that aging is a good and natural process to be embraced as a necessary and positive aspect of (...) life, where the aim is to improve the quality of existing lifespan and “compress” morbidity. Another view is that aging is undesirable, and that rejuvenation and indeed immortality are possible since the biological basis of aging is understood, and therefore, strategies are possible for engineering negligible senescence. Finally, a hybrid approach is that life span can be extended by anti‐aging medicines but with uncertain effects on health. While these advances offer much promise, the ethical perspectives are seldom discussed in cross‐disciplinary settings. This article discusses some of the key ethical issues arising from recent advances in biogerontology. (shrink)

Emotion detection and management have emerged as pivotal areas in humancomputer interaction, offering potential applications in healthcare, entertainment, and customer service. This study explores the use of deep learning (DL) models to enhance emotion recognition accuracy and enable effective emotion regulation mechanisms. By leveraging large datasets of facial expressions, voice tones, and physiological signals, we train deep neural networks to recognize a wide array of emotions with high precision. The proposed system integrates emotion recognition with adaptive management strategies that provide (...) personalized feedback and interventions based on detected emotional states. Our approach surpasses traditional machine learning methods, demonstrating superior performance in real-time applications. (shrink)

The topic of this article is consciousness and, in it, I will theorize what consciousness is like and where it arises from. The work began to emerge and develop over time starting from my belief that consciousness is a physical self-referential phenomenon; thus, my attention was focused on the research for a self-referential process. I was confident that I could satisfy my curiosity through the reductionist method adopted by science. Unfortunately, neuroscientists and philosophers of mind realized that the attempts to (...) explain consciousness with this method have all proved inconclusive. For this reason, they are now trying to address the problem of consciousness with non-reductionist methods. As for me, I have always remained faithful to reductionism, but with the conviction that quantum mechanics, even though capable of making predictions with an extraordinary degree of accuracy, is a theory founded on wrong concepts. Thus, surprisingly, I have found a solution to the mystery of consciousness, perceiving a way to explain what it is like at its fundamental level in the field of quantum mechanics and, particularly, in one of its counterintuitive and generally less debated aspects among physicists today, but which aroused great interest in me: I am referring to the spin of the electron that will be described in this paper as a self-interacting process. This paper will also offer a rational explanation of the results obtainable in all experiments for measuring the spin of electrons through Stern-Gerlach magnets. In addition, my theory of consciousness is susceptible to experimental control. (shrink)

Our manuscript addresses the foundational question of cognitive science: how do we know? Specifically, examination of the mathematics of acquiring mathematical knowledge revealed that knowing-within-mathematics is reflective of knowing-in-general. Based on the correspondence between ordinary cognition (involving physical stimuli, neural sensations, mental concepts, and conscious percepts) and mathematical knowing (involving objective particulars, measured properties, abstract theories, and concrete models), we put forward the functorial semantics of mathematical knowing as a formalization of cognition. Our investigation of the similarity between mathematics and (...) cognition led us to argue against the compartmentalization of scientific knowledge and ordinary cognition, and make a case for the understanding of the basic science of knowing in terms of functorial semantics. Recognizing functorial semantics as an elementary form of cognition can help advance cognitive science the way calculus helped in the advancement of physics. (shrink)

A theory of rationality is a theory that evaluates instances of reasoning as rational, irrational, or (ir)rational to some degree. Theories can be categorized as rule-based or consequentialist. Rule-based theories say that rational reasoning accords with certain rules (e.g., of logic or probability). Consequentialist theories say that rational reasoning tends to produce good consequences. For instance, the reliabilist takes rationality to be reasoning that tends to produce mostly true beliefs. The pragmatist takes it to be reasoning that tends to produce (...) mostly useful beliefs. This article reviews some of the features and the challenges of rule-based, reliabilist, and pragmatist theories of rationality. (shrink)

Abstract: The incorporation of Artificial Intelligence (AI) into educational technology has dramatically transformed learning through Intelligent Tutoring Systems (ITS). These systems utilize AI to offer personalized, adaptive instruction tailored to each student's needs, thereby improving learning outcomes and engagement. This paper examines the development and impact of ITS, focusing on AI technologies such as machine learning, natural language processing, and adaptive algorithms that drive their functionality. Through various case studies and applications, it illustrates how ITS have revolutionized traditional educational methods (...) and addresses the challenges and limitations, including data privacy and system biases. The discussion also covers future directions in ITS development, highlighting emerging trends and potential advancements. The goal is to provide a thorough understanding of how ITS use AI to enhance educational experiences and suggest avenues for future research in this evolving field. (shrink)

Recently there is an increasing technological development in intelligent tutoring systems. This field has become interesting to many researchers. In this paper, we present an intelligent tutoring system for teaching information security. This intelligent tutoring systems target the students enrolled in Advanced Topics in Information Security in the faculty of Engineering and Information Technology at Al-Azhar University in Gaza. Through which the student will be able to study the course and solve related problems. An evaluation of the intelligent tutoring (...) systems was carried out and the results were promising. (shrink)