RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE AS ALTERAÇÕES DO CORPO LÚTEO EM VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__7. ALTERAÇÕES DO CORPO LÚTEO -/- A estrutura funcional desenvolve-se a partir da cavidade folicular após a ovulação. O corpo lúteo é constituído pelas células da teca interna (pequenas e ativas na primeira fase do seu desenvolvimento) e células da granulosa (grandes e ativas na segunda metade do seu (...) desenvolvimento). As principais características de cada tipo de célula podem resumir-se da seguinte forma: As células pequenas são mais sensíveis à ação da LH porque possui uma quantidade maior de receptores biologicamente ativos para esta hormona e a resposta é mediada pelo sistema AMPc-adelinato ciclase. As grandes células lúteas têm menos receptores para a LH (a maior quantidade são para a PGF2α e a PGE2), e são as responsáveis pela produção da oxitocina luteal (BAH, et al. 2006; CAMPO, 2003). Contrariamente às pequenas células lúteas, a produção de progesterona (P4) é parcialmente controlada pelo sistema Ca+2 - Fosfatil inositol-quinase C (CAMPO, 2003). A regulação da função do corpo lúteo é um mecanismo complexo. Nela intervêm fatores tróficos e líticos que estão presentes em forma simultânea durante todo o ciclo estral, e portanto a estimulação ou inibição da síntese e secreção de P4 depende do balanço entre estes fatores. (CAMPO, 2003). Dentro dos fatores tróficos, os nutrientes desempenham um papel relevante sobre a luteólise e as funções luteotrópicas, entre estas pode-se citar a ação das seguintes: -/- 7.1 Vitaminas Deficiência em betacarotenos. Vitamina A é um termo genérico que designa qualquer composto com atividade de retinol, o trans-retinol, é o composto base, sua forma aldeído e ácido são chamados de retinol e ácido retinóico, respectivamente. Por outro lado, a forma ativa da Vitamina A participa no mecanismo da visão, como 11-cis-retinal. Adicionalmente, o betacaroteno, considerado uma provitamina A é a única forma em que esta encontra nas plantas. Em sentido nutricional, a família da Vitamina A compreende todos os compostos que possuem atividade de retinol, incluindo cerca de cinquenta carotenoides que possuem atividade de provitamina A, aceitando-se que o mais ativo é o trans-betacaroteno (TORRES, et al. 2002). As vitaminas que são necessárias para o crescimento e a produção, também são essenciais para a reprodução. As recomendações atuais de vitamina A são de 75.000 UI/dia durante a lactação e 80.000 UI/dia (nota: 1 mg de Vitamina A = 400 UI) durante o período seco nas vacas leiteiras. A suplementação com vitamina A tem pouco risco de toxicidade, enquanto a sua deficiência pode retardar o aparecimento do primeiro cio/estro, induzir cios/estros silenciosos, aumentar o número de quistos ováricos, reduzir os índices de concepção, causar abortos, mortes embrionárias e ocasionar o nascimento de bezerros debilitados e fracos, uma vez que não irão nascer com os índices e requerimentos ideais de nutrientes passados da mãe para o feto pela placenta, e que, já que a mãe possui deficiência nutricional, o colostro não terá o efeito completo para passar a imunidade essencial ao neonato. Embora os mecanismos de ação não sejam claros, foram notificadas maiores secreções de esteroides ováricos quando as concentrações de β-carotenos no fluido folicular foram elevadas; logo, foram observadas maiores concentrações elevadas de β- estradiol e vitamina A nos folículos que terminaram em ovulação do que naqueles que terminaram em atresia. Para evitar as perdas reprodutivas por deficiência de vitamina A, pode-se optar pela administração oral ou injetável desta ao animal, mediante dois métodos: o primeiro consiste em adicionar 1 a 2,5 kg de premix vitamínico em 1 tonelada de grãos o que supre de 4 a 6.000 UI o que é desejável; o segundo é a administração via injetável em quantidades vide bula do fármaco. 7.2 Minerais O excesso de fósforo é absorvido principalmente no intestino delgado dos mamíferos através de um mecanismo de transporte ativo dependente do sódio, que é estimulado pela pró-hormona 1,25- hidroxivitamina D3. Os ruminantes são capazes de absorver o fósforo dietético em proporção direta às quantidades presentes na ração. Estima-se que aproximadamente 1% do corpo animal é composto de fósforo, do qual 85% está presente nos dentes e no tecido ósseo. Os tecidos moles são capazes de conter entre 0,15-0,20% de fósforo sob a forma de fosfoproteínas, nucleoproteínas, fosfolipídios, fosfato creatinina, adenosintrifosfato, glicose-6-fosfato, etc. Ao nível do plasma sanguíneo, o fósforo apresenta valores de 12,09 mg/dl. Os valores plasmáticos de fósforo são regulados principalmente pelo rim, sendo observado um aumento na excreção urinária do elemento inorgânico quando este excede a capacidade de transporte (REBOLLAR & MATEOS, 1999). O fósforo faz parte dos fosfolipídios, que são importantes no transporte de lipídios e seu metabolismo, como componente das membranas celulares. O fosfato faz parte do RNA e do DNA, componentes celulares vitais, e são essenciais para a síntese proteica. O fosfato faz parte de sistemas enzimáticos como a cocarboxilase e NAD, portanto está envolvido em todos os processos de síntese e regulação energética, dado que o corpo lúteo requer altas quantidades de energia para a síntese celular e hormonal, um excesso de fósforo pode bloquear a capacidade renal da sua regulação gerando um desequilíbrio catiônico que descompensa a relação Na:K, já que deverão ser excretados íons fosfato para regular o equilíbrio ácido-básico, desta forma, os processos celulares em tecidos de alta sensibilidade como o ovário serão afetados em sua função. A situação para prevenção de problemas relacionados ao fósforo (P) já foi tratada em assuntos anteriores, porém, sempre vale frisar para o leitor fiel que me lê que as exigências de P presentes na matéria seca (MS) variam entre 0,17 e 0,59% de P por kg/MS para bovinos de corte e em 0,32 a 0,44% por kg/MS para o gado leiteiro. Dessa forma, dados obtidos por pesquisas, ditam que para a mantença de uma vaca ou quaisquer outra categoria bovina o ideal é o consumo de 1.43 g/100 kg de peso vivo (PV), garantindo assim a prevenção de possíveis afecções reprodutivas como as alterações do corpo lúteo. Gramíneas, forragens, leguminosas e os concentrados fornecem muito bem os requerimentos de fósforo para os animais, todavia deve-se estar atento as relações e dependências do P com outros elementos como o Ca e a relação Na:K (10-15:1 idealmente). 7.3 Compostos estrogênicos Os fitoestrogênios afetam repetidamente a estabilidade do corpo lúteo. Os compostos estrogênicos encontrados principalmente em leguminosas pertencem principalmente a três grupos: isoflavanos, isoflavonas, presentes no gênero Trifolium e praticamente restritos às leguminosas, e cumestanos, que foram estudados na alfafa (Medicago sativa) e na Melilotus alba. Todas as isoflavonas sofrem algum grau de transformação no rúmen, sendo o Isoflavonoide formononetina, na realidade um pró-estrógeno, o único que se ativa no ecossistema ruminal ao ser convertido em equol, enquanto que as demais são degradadas a produtos inativos (RAMOS, et al. 1998). Por fim, a alta concentração no sangue do equol retarda a retroalimentação sobre a hipófise mediante a qual se reduzem os níveis de FSH para dar lugar à onda ovulatória de LH, se esta não ocorrer, o corpo lúteo obviamente não se formará. O conhecimento acerca dos estrogênios na alimentação animal é defasado nos livros sobre o tema, no entanto, o criador pode ficar tranquilo no que tange o tema na prática da sua fazenda e dos seus animais, uma vez que tal elemento é muito bem fornecido naturalmente por meio dos alimentos volumosos presentes no seu pasto. -/- Apoio -/- Realização -/- REFERÊNCIAS BIBLIOGRÁFICAS BAH, Mamadou M. et al. Role of intraluteal prostaglandin F2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins & other lipid mediators, v. 79, n. 3-4, p. 218-229, 2006. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. CAMPO, E. Comportamiento reproductivo del ganado Bovino y Bufalino. 2003. Universidad Agraria de la Habana. Havana, 2003. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. HURLEY, W. L.; DOANE, R. M. Recent developments in the roles of vitamins and minerals in reproduction. Journal of Dairy Science, v. 72, n. 3, p. 784-804, 1989. KUMAR, Sudhir et al. Importance of micro minerals in reproductive performance of livestock. Veterinary world, v. 4, n. 5, p. 230, 2011. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. RAMOS, Graciano et al. Los compuestos secundarios de las plantas en la nutrición de los herbívoros. Archivos de Zootecnia. 47: 597-620, 1998. REBOLLAR, Paloma García; MATEOS, Gonzalo González. El fósforo en nutrición animal. Necesidades, valoración de materias primas y mejora de la disponibilidad. CURSO DE ESPECIALIZACIÓN FEDNA. Avances en nutrición y alimentaciín animal, XV, p. 19-64, 1999. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. TEIXEIRA, J. C. Nutrição de ruminantes. Lavras: FAEPE, 1992. TORRES, M. et al. Aspectos Farmacológicos relevantes de las Vitaminas Antioxidantes (E, A y C). Archivos Venezolanos de Farmacología y Terapéutica, v. 21, n. 1, p. 22-27, 2002. YASOTHAI, R. Importance of minerals on reproduction in dairy cattle. International Journal of Science, Environment and Technology, v. 3, n. 6, p. 2051-2057, 2014. -/- Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020. (shrink)

In this paper Sullins argues that in certain circumstances robots can be seen as real moral agents. A distinction is made between persons and moral agents such that, it is not necessary for a robot to have personhood in order to be a moral agent. I detail three requirements for a robot to be seen as a moral agent. The first is achieved when the robot is significantly autonomous from any programmers or operators of the machine. The second is when (...) one can analyze or explain the robot's behavior only by ascribing to it some predisposition or 'intention' to do good or harm. And finally, robot moral agency requires the robot to behave in a way that shows and understanding of responsibility to some other moral agent. Robots with all of these criteria will have moral rights as well as responsibilities regardless of their status as persons. (shrink)

Demonstratives seem to have posed a severe difficulty for Frege’s philosophy of language, to which his doctrine of incommunicable senses was a reaction. In “The Thought,” Frege briefly discusses sentences containing such demonstratives as “today,” “here,” and “yesterday,” and then turns to certain questions that he says are raised by the occurrence of “I” in sentences (T, 24-26). He is led to say that, when one thinks about oneself, one grasps thoughts that others cannot grasp, that cannot be communicated. However, (...) nothing could be more out of the spirit of Frege’s account of sense and thought than an incommunicable, private thought. In the first part of the paper, I explain the problem demonstratives pose for Frege, and explore three ways he might have dealt with it. I argue that none of these ways provides Frege with a solution to his problem consistent with his philosophy of language. The first two are plausible as solutions, but contradict his identification of the sense expressed by a sentence with a thought. The third preserves the identification, but is implausible. In the second part, I suggest that Frege was led to his doctrine of incommunicable senses as a result of some appreciation of the difficulties his account of demonstratives faces, for these come quickly to the surface when we think about “I.” I argue that incommunicable senses won’t help. I end by trying to identify the central problem with Frege’s approach, and sketching an alternative. (shrink)

This paper introduces a new, expanded range of relevant cognitive psychological research on collaborative recall and social memory to the philosophical debate on extended and distributed cognition. We start by examining the case for extended cognition based on the complementarity of inner and outer resources, by which neural, bodily, social, and environmental resources with disparate but complementary properties are integrated into hybrid cognitive systems, transforming or augmenting the nature of remembering or decision-making. Adams and Aizawa, noting this distinctive complementarity argument, (...) say that they agree with it completely: but they describe it as “a non-revolutionary approach” which leaves “the cognitive psychology of memory as the study of processes that take place, essentially without exception, within nervous systems.” In response, we carve out, on distinct conceptual and empirical grounds, a rich middle ground between internalist forms of cognitivism and radical anti-cognitivism. Drawing both on extended cognition literature and on Sterelny’s account of the “scaffolded mind” (this issue), we develop a multidimensional framework for understanding varying relations between agents and external resources, both technological and social. On this basis we argue that, independent of any more “revolutionary” metaphysical claims about the partial constitution of cognitive processes by external resources, a thesis of scaffolded or distributed cognition can substantially influence or transform explanatory practice in cognitive science. Critics also cite various empirical results as evidence against the idea that remembering can extend beyond skull and skin. We respond with a more principled, representative survey of the scientific psychology of memory, focussing in particular on robust recent empirical traditions for the study of collaborative recall and transactive social memory. We describe our own empirical research on socially distributed remembering, aimed at identifying conditions for mnemonic emergence in collaborative groups. Philosophical debates about extended, embedded, and distributed cognition can thus make richer, mutually beneficial contact with independently motivated research programs in the cognitive psychology of memory. (shrink)

Two options are incommensurate in value if neither is better than the other, and if a small improvement or worsening of one does not necessarily make it determinately better or worse than the other. If a person faces a sequence of choices between incommensurate options, she may end up with a worse options than she could have had, even though none of her choices are irrational. Yet it seems that rationality should save her from this bad outcome. This is the (...) practical problem posed by incommensurability of values, and it may be solved by a new account of practical reasoning. (shrink)

[Edited from Conclusion section:] We have looked at various challenging issues to do with getting connectionism to cope with high-level cognitive activities such a reasoning and natural language understanding. The issues are to do with various facets of generalization that are not commonly noted. We have been concerned in particular with the special forms these issues take in the arena of propositional attitude processing. The main problems we have looked at are: (1) The need to construct explicit representations of generalizations, (...) not just generalize correctly to individual cases; (2) The need to be able to match two or more complex short-term information structures, to enable rapid generalization from recent examples rather than from long-term memories; (3) The need to represent and reason with anomalous combinations of concepts; (4) The need to perform embedded reasoning. This presents special problems for systems using non-concatenative representations (as in mainstream connectionist approaches). We also touched on vague quantification in attitude report complements. Neither this topic nor that of analogies between short-term structures (point 2) has been adequately addressed in the symbolic framework, let alone in connectionism. -/- The opportunities and problems covered are put forward as things worth being optimistic about or pessimistic about, respectively. They are not put forward as decisive arguments for or against connectionism. The hope is that this chapter contributes to a greater understanding of the connectionist/symbolist gap by presenting some unusual issues and by throwing new light on some well known ones. (shrink)

Synthetic organisms are at the same time organisms and artifacts. In this paper we aim to determine whether such entities have a good of their own, and so are candidates for being directly morally considerable. We argue that the good of non-sentient organisms is grounded in an etiological account of teleology, on which non-sentient organisms can come to be teleologically organized on the basis of their natural selection etiology. After defending this account of teleology, we argue that there are no (...) grounds for excluding synthetic organisms from having a good also grounded in their teleological organization. However, this comes at a cost; traditional artifacts will also be seen as having a good of their own. We defend this as the best solution to the puzzle about what to say about the good of synthetic organisms. (shrink)

The analysis of desire ascriptions has been a central topic of research for philosophers of language and mind. This work has mostly focused on providing a theory of want reports, that is, sentences of the form ‘S wants p’. In this paper, we turn from want reports to a closely related but relatively understudied construction, namely hope reports, that is, sentences of the form ‘S hopes p’. We present two contrasts involving hope reports and show that existing approaches to desire (...) fail to explain these contrasts. We then develop a novel account that combines some of the central insights in the literature. We argue that our theory provides an elegant account of our contrasts and yields a promising analysis of hoping. (shrink)

Remembering is one of the most characteristic and most puzzling of human activities. Personal memory, in particular – the ability mentally to travel back into the past, as leading psychologist Endel Tulving puts it – often has intense emotional or moral significance: it is perhaps the most striking manifestation of the peculiar way human beings are embedded in time, and of our limited but genuine freedom from our present environment and our immediate needs. Memory has been significant in the history (...) of philosophy as much in relation to ethics and to epistemology as in theories of psyche, mind, and self. (shrink)

I start with a brief assessment of the implications of Sterelny’s anti-individualist, anti-internalist apprentice learning model for a more historical and interdisciplinary cognitive science. In a selective response I then focus on two core features of his constructive account: collaboration and skill. While affirming the centrality of joint action and decision making, I raise some concerns about the fragility of the conditions under which collaborative cognition brings benefits. I then assess Sterelny’s view of skill acquisition and performance, which runs counter (...) to dominant theories that stress the automaticity of skill. I suggest that it may still overestimate the need for and ability of experts to decompose and represent the elements of their own practical knowledge. (shrink)

It is widely accepted in epistemology that knowledge is factive, meaning that only truths can be known. We argue that this theory creates a skeptical challenge: because many of our beliefs are only approximately true, and therefore false, they do not count as knowledge. We consider several responses to this challenge and propose a new one. We propose easing the truth requirement on knowledge to allow approximately true, practically adequate representations to count as knowledge. In addition to addressing the skeptical (...) challenge, this view also coheres with several previous theoretical proposals in epistemology. (shrink)

A critical explanation of Ernest Sosa's bi-level virtue epistemology.

In this paper, we propose a novel account of desire reports, i.e. sentences of the form 'S wants p'. Our theory is partly motivated by Phillips-Brown's (2021) observation that subjects can desire things even if those things aren't best by the subject's lights. That is, being best isn't necessary for being desired. We compare our proposal to existing theories, and show that it provides a neat account of the central phenomenon.

The philosophy of superdeterminism is based on a single scientific fact about the universe, namely that cause and effect in physics are not real. In 2020, accomplished Swedish theoretical physicist, Dr. Johan Hansson published a physics proof using Albert Einstein’s Theory of Special Relativity that our universe is superdeterministic meaning a predetermined static block universe without cause and effect in physics. Because of this new scientific understanding of our universe, the nature of miracles must be predetermined events that occur within (...) our static block universe. The predetermined static nature of our universe lends itself to the predetermined occurrence of miracles without the necessity of any intervention in time or interference with the laws of physics. Moreover, the new philosophy of superdeterminism supports the existence of a Creator God capable of predetermining the occurrence of miracles in human events. (shrink)

This paper addresses relations between memory and imagery in expert sport in relation to visual or visuospatial perspective. Imagining, remembering, and moving potentially interact via related forms of episodic simulation, whether future- or past-directed. Sometimes I see myself engaged in action: many experts report switching between such external visual perspectives and an internal, 'own-eyes', or field perspective on their past or possible performance. Perspective in retrieval and in imagery may be flexible and multiple. I raise a range of topics for (...) empirical research on perspective and visualization. (shrink)

Demonstrative logic, the study of demonstration as opposed to persuasion, is the subject of Aristotle's two-volume Analytics. Many examples are geometrical. Demonstration produces knowledge (of the truth of propositions). Persuasion merely produces opinion. Aristotle presented a general truth-and-consequence conception of demonstration meant to apply to all demonstrations. According to him, a demonstration, which normally proves a conclusion not previously known to be true, is an extended argumentation beginning with premises known to be truths and containing a chain of reasoning showing (...) by deductively evident steps that its conclusion is a consequence of its premises. In particular, a demonstration is a deduction whose premises are known to be true. Aristotle's general theory of demonstration required a prior general theory of deduction presented in the Prior Analytics. His general immediate-deduction-chaining conception of deduction was meant to apply to all deductions. According to him, any deduction that is not immediately evident is an extended argumentation that involves a chaining of intermediate immediately evident steps that shows its final conclusion to follow logically from its premises. To illustrate his general theory of deduction, he presented an ingeniously simple and mathematically precise special case traditionally known as the categorical syllogistic. (shrink)

This paper is a tentative step towards a historical cognitive science, in the domain of memory and personal identity. I treat theoretical models of memory in history as specimens of the way cultural norms and artifacts can permeate ('proto')scientific views of inner processes. I apply this analysis to the topic of psychological control over one's own body, brain, and mind. Some metaphors and models for memory and mental representation signal the projection inside of external aids. Overtly at least, medieval and (...) Renaissance theorists agreed that such models had to allow for, or even guarantee, some conception of cognitive order and discipline. Individual memory traces had to be independent, not mixed up or interfering with others. The long tradition of improving or bypassing 'natural memory' by deliberately internalizing artefactual models was part of an arduous process of self-fashioning. Moral panic about confusion and mixture features centrally in the imposition of cognitive discipline in local memory traditions. (shrink)

This essay takes logic and ethics in broad senses: logic as the science of evidence; ethics as the science justice. One of its main conclusions is that neither science can be fruitfully pursued without the virtues fostered by the other: logic is pointless without fairness and compassion; ethics is pointless without rigor and objectivity. The logician urging us to be dispassionate is in resonance and harmony with the ethicist urging us to be compassionate.

Early modern critics of materialism (and of associated doctrines like determinism and mechanism) sometimes employed a transcendental argument form. If materialism were true, then some valuable feature of reality could not exist; but that feature does exist; therefore materialism is false. Depending on current context and concerns, the valuable 'X' in question might be God, the soul, hell, objective morality, free will, conscience, truth, knowledge, social order, or justice and the law: all, in the critics' eyes, obvious and unchallengeable realities (...) which materialism would, impossibly, extinguish.1 As David Hawkes notes in his delightfully provocative essay, it is because Hell is so manifestly real, in both the play and its world, that Faustus manifestly refutes himself in telling Mephistopheles that it is a fable. The success of such transcendental arguments relies on the truth of both their premises: Hell really must exist, and Faustus's materialism must really be incompatible with its existence. Hawkes celebrates early modern moralists who focussed on the alleged worldly and carnal roots and consequences of 'philosophical materialism', who attacked its proponents as villainous, self-interested, and depraved. (shrink)

How does evidence figure into the reasoning of an agent? This is an intricate philosophical problem but also one we all encounter in our daily lives. In this chapter, we identify the problem and outline a possible solution to it. The problem arises, because the fact that it is up to us whether we do something makes a difference to how we should think of the evidence concerning whether we will actually do it. Otherwise we regard something that is up (...) to us as if it were not: We regard something that is up to us as if it were the outcome of a lottery. Nonetheless, we would be wrong to ignore the evidence. Otherwise we could not make a rational decision. In this chapter, we first show that a decision-theoretic approach to this problem cannot succeed. This approach does not explain how we can take evidence into account in practical reasoning without making predictions concerning matters that are up to us. It also gives rise to incoherence between our practical and our theoretical conclusions. We then argue that what is required to solve the problem is recognizing that beliefs about matters that are up to us can be grounded in practical reasoning. We argue that such beliefs are not subject to an evidential norm, because they are not meant to reflect a reality that is independent of them but instead are meant to bring about the reality they represent. Finally, we argue that, even if we are fully rational agents, we will sometimes lack practical knowledge of what we will do. That is because when it is practically rational to do something that will require resolve, we may be in a position to rationally conclude that we will do it, even though we have evidence that there is a non-negligible chance that we won’t. In such cases, our evidence serves as a defeater for our practical knowledge. (shrink)

The representation of propositional attitudes (beliefs, desires, etc.) and the analysis of natural-language, propositional-attitude reports presents difficult problems for cognitive science and artificial intelligence. In particular, various representational approaches to attitudes involve the incorrect “imputation,” to cognitive agents, of the use of artificial theory-laden notions. Interesting cases of this problem are shown to occur in several approaches to attitudes. The imputation problem is shown to arise from the way that representational approaches explicate properties and relationships, and in particular from the (...) way they explicate propositional attitudes themselves. Another factor contributing to imputation is the compositional nature of typical semantic approaches to propositional-attitude reports. Some strategies for avoiding undesirable imputation are examined. One of the main conclusions is that the importance of imputations that arise in a representation scheme depends strongly on the use to which the scheme is put -- on whether, for instance, the scheme is used as part of a formal, objective account of natural language, or is used rather as a representational tool within an agent. (shrink)

This paper raises obvious questions undermining any residual confidence in Mates work and revealing our embarrassing ignorance of true nature of Stoic deduction. It was inspired by the challenging exploratory work of JOSIAH GOULD.

There are two different ways of understanding alienation: as a condition and as a struggle. On this distinction turns the whole theory and practice of Marxism.

What a person is doing often depends on that person’s thought about what they are doing, or about the wider circumstances of their action. For example, whether my killing is murder or manslaughter depends, in part, on whether I understand that what I am doing is killing you, and on whether I understand that my killing is unjustified. Similarly, if I know that the backpack I am taking is yours, then my taking it may be an act of theft; but (...) it is not theft if I simply mistook your backpack for my own. And if I don’t know that in signing a document I’m promising to do some thing, then in signing it I’m not promising to do this at all. -/- According to Elizabeth Anscombe, a central task of philosophical psychology is to articulate this dependency of action on thought. And in a range of papers published during the 1960s, Anscombe sought to elucidate various aspects of this dependency. In this paper we give a systematic overview of how Anscombe understands this dependency, and in the process reveal the conceptual framework underlying Anscombe’s thinking about perception, desire, intention, voluntariness, responsibility, guilt, and sin. (shrink)

The study of remembering is both compelling and challenging, in part, because of the multiplicity and the complexity of influences on memory. Whatever their interests, memory researchers are always aware of the many different factors that can drive the processes they care about. A search for the phrase ‘influences on memory’ confirms this daunting and exhilarating array of influences, of many different kinds, operating at many different timescales, and presumably often interacting in ways that we can’t yet imagine, let alone (...) model. There are hormonal and neuromodulatory, genetic and pharmacological, developmental and age-related influences; there are influences of arousal, stress, gender, mood, emotion, sleep and personality; there are unconscious, schematic or semantic influences, and there are influences of context, situation, task and environment. There are many aspects of ‘media influence on memory’ (Loftus and Banaji, 1989; Strange and Garry, 2007), and, of course, there are both ‘social influences on memory’ (Echterhoff and Hirst, 2009) and ‘cultural influences on memory’ (Gutchess and Indeck, 2009). Notoriously, there are numerous ‘suggestive influences’ on memory (Loftus, 2003): influences of misinformation (Seifert, 2002; Wright and Loftus, 1998), or of ‘memory conformity’ (Gabbert et al., 2006) and ‘memory contagion’ (Roediger et al., 2002). People who know each other well, such as intimate couples, ‘may be well practised in yielding to each other’s influence and incorporating their partner’s information into their own memories of the past’ (French et al., 2008: 264). (shrink)

This was a class handout that I turned into a publication. As its title indicates, it's about the relation (or non-relation) of (ethical) cultural relativism to tolerance. Core elements of the paper were later absorbed into sections 5K, 6M, and 7K of my paper "Cultural Relativism" (2000), which is listed (and downloadable) on my PhilPapers page.

Nuestro interés en el contenido mental no-conceptual es, principalmente, la articulación de una versión sustantiva (no-trivial) de esta clase de contenido en la experiencia perceptual. El debate acerca del contenido no-conceptual ha girado, en su mayor parte, alrededor de su existencia; y los argumentos que se han ofrecido en su favor abogan por una versión no sustantiva según la cual el contenido no-conceptual es aquel que no satisface ciertos requisitos conceptuales. Así, para desarrollar una versión sustantiva del contenido mental no-conceptual (...) hemos apelado a la versión de la experiencia perceptual de propiedades espaciales ofrecida por Evans (1982 cap. 6). A partir de esto desarrollamos un nuevo argumento a favor del contenido no-conceptual de la experiencia perceptual que lo vincula a la actividad característica de la experiencia perceptual. Por último, exponemos uno de los ataques de McDowell (1996) a la noción de contenido no-conceptual y presentamos nuestras réplicas a este ataque, mostrando su insuficiencia. Al mostrar que la crítica de McDowell no es exitosa, consideramos que podríamos tener una versión del contenido no-conceptual de la experiencia que es inmune a esta línea de argumentación. (shrink)

The notion of Simulative Reasoning in the study of propositional attitudes within Artificial Intelligence (AI) is strongly related to the Simulation Theory of mental ascription in Philosophy. Roughly speaking, when an AI system engages in Simulative Reasoning about a target agent, it reasons with that agent’s beliefs as temporary hypotheses of its own, thereby coming to conclusions about what the agent might conclude or might have concluded. The contrast is with non-simulative meta-reasoning, where the AI system reasons within a detailed (...) theory about the agent’s (conjectured) reasoning acts. The motive within AI for preferring Simulative Reasoning is that it is more convenient and efficient, because of a simplification of the representations and reasoning processes. The chapter discusses this advantage in detail. It also sketches the use of Simulative Reasoning in an AI natural language processing system, ATT-Meta, that is currently being implemented. This system is directed at the understanding of propositional attitude reports. In ATT-Meta, Simulative Reasoning is yoked to a somewhat independent set of ideas about how attitude reports should be treated. Central here are the claims that (a) speakers often employ commonsense (and largely metaphorical) models of mind in describing agents’ attitudes, (b) the listener accordingly needs often to reason within the terms of such models, rather than on the basis of any objectively justifiable characterization of the mind, and (c) the commonsense models filter the suggestions that Simulative Reasoning comes up with concerning target agents’ reasoning conclusions. There is a yet tighter connection between the commonsense models and the Simulative Reasoning. It turns out that Simulative Reasoning can be rationally reconstructed in terms of a more general type of reasoning about the possibly-counterfactual “world” that the target agent believes in, together with an assumption that that agent has a faithful representation of the world. In the ATT-Meta approach, the reasoner adopts that assumption when it views the target agent through a particular commonsense model (called IDEAS-AS-MODELS). (shrink)

Every metaphysic, according to Reiner Schürmann, involves the positing of a first principle for thinking and doing whereby the world becomes intelligible and masterable. What happens when such rules or norms no longer have the power they previously had? According to Cornelius Castoriadis, the world makes sense through institutions of imaginary significations. What happens when we discover that these significations and institutions truly are imaginary, without ground? Both thinkers begin their ontologies by acknowledging a radical finitude that threatens to destroy (...) meaning or order. For Schürmann it is the ontological anarchy revealed between epochs when principles governing modes of thinking and doing are foundering but new principles to take their place have not yet emerged. For Castoriadis it is chaos that names the indeterminationdetermination that governs the unfolding of the socio-historical with contingency and unpredictability. And yet for both thinkers their respective ontologies have political or ethical implications. On the basis of the anarchy of being, Schürmann unfolds an anarchic praxis or ethos of “living without why.” And on the basis of his notion of being as chaos, Castoriadis develops his political praxis of autonomy. The challenge for both is this move from ontology to practical philosophy, how to bridge theory and practice. The key for both seems to be a certain ontologically derived sense of freedom. In this paper, I analyze and compare their respective thoughts, and pursue the question of how anarchy or chaos and the implied sense of an ontological freedom might be made viable and sensible for human praxis, how radical finitude in the face of ontological groundlessness might nevertheless serve to situate a viable political praxis. (shrink)

The position that Stokes’s Thinking and Perceiving aims to overthrow is committed to the idea that the facts about one’s propositional attitudes and the facts about one’s perceptual experiences are alike grounded in facts about representations (in various formats) that are being held in a short or long term memory store, so that computations can be performed upon them. Claims about modularity are claims about the distinctness of these memory stores, and of these representations. One way in which to reject (...) these claims is to deny only that distinctness. A more radical way would be to reject the underlying idea that facts about perception and facts about propositional attitudes are alike grounded in facts about stored representations. Although the more radical approach might seem to face a problem concerning causal efficacy, I suggest that the way is open for Stokes to take it. (shrink)

The artefacts produced by artists during their creation of works of art are very various: paintings, writings, musical scores, and so on. I have a general thesis to offer about the relations of artefacts and artworks, but within the confines of this article I shall mainly discuss cases drawn from the art of painting, central specimens of which seem to be autographic in Nelson Goodman's sense, namely such that even the most exact duplication of them does not count as producing (...) the same work of art. My view will be that an artwork (such as a painting) and its associated artefact are not identical, and nor is the artefact in any sense part of the painting in question,2 but that nevertheless it is still possible to maintain the view that paintings are autographic (which view I shall call l the autographic thesis). I shall proceed initially through presentation of some counter-examples to common assumptions as to the relations of artefacts and artworks, and then present an alternative 'representational' theory of their relations. (shrink)

In his contribution to the first issue of Memory Studies, Jeffrey Olick notes that despite “the mutual affirmations of psychologists who want more emphasis on the social and sociologists who want more emphasis on the cognitive”, in fact “actual crossdisciplinary research … has been much rarer than affirmations about its necessity and desirability” (2008: 27). The peculiar, contingent disciplinary divisions which structure our academic institutions create and enable many powerful intellectual cultures: but memory researchers are unusually aware that uneasy faultlines (...) and glaring gulfs lie in the uncertain zones between them. The processes of memory are simultaneously natural and cultural. But our difficulties in imagining even fragments of a genuinely integrated framework for understanding diverse memory-related phenomena do not arise from a simple ‘two-cultures’ problem: it’s not as if there are substantially unified visions of memory within either ‘the sciences’ or ‘the humanities’. (shrink)

The science of the mind, and of consciousness in particular, needs carefully to consider people's common-sense views of the mind, not just what the mind really is. Such views are themselves an aspect of the nature of (conscious) mind, and therefore part of the object of study for a science of mind. Also, since the common-sense views allow broadly successful social interaction, it is reasonable to look to the common-sense views for some rough guidance as to the real nature of (...) the mind. On the other hand, to the extent that common-sense views are inaccurate, and perhaps even in gross conflict with the true nature of the mind, one interesting scientific question is: why do we hold such views, given our access to our own minds? Why should introspection be limited in a way that allows inaccurate views to hold sway? Now, common-sense views of the mind are revealed in natural language discourse that describes mental states, and such descriptions are largely metaphorical. The metaphors are used within thinking about the mind as well as in language. Therefore the study of metaphor is central to the study of mind. The present article is a preliminary study of the importance of metaphor in the scientific study of consciousness. It concentrates on analysing the nature of a range of important metaphors of mind, briefly discussing the extent to which they can be used to describe or qualify states of consciousness, and pointing to important questions about the nature of consciousness that the study of the metaphors raises. The article further conjectures that the reason people use metaphors in describing themselves is often not (just) that they have intellectually worked out some structural analogy --- e.g., between interactions of physical objects in physical space and interactions of ideas in the mind --- but rather that they {\it feel} their own minds to be as described by the metaphor --- e.g., they feel that the ideas in their minds are interacting physical entities. This matter of how a mind feels to itself is an aspect of the central issue of consciousness, namely its phenomenal quality. -/- (NB: The archived file is a preprint. However, it is substantially the same as the published version.). (shrink)

Recent work in the methodology of connectionist explanation has I'ocrrsccl on the notion of levels of explanation. Specific issucs in conncctionisrn hcrc intersect with rvider areas of debate in the philosophy of psychology and thc philosophy of science generally. The issues I raise in this chapter, then, are not unique to cognitive science; but they arise in new and important contexts when connectionism is taken seriously as a model of cognition. The general questions are the relation between levels and the (...) status of levels which have no obvious relation to others. In speaking of levels, what is the connection, if there is one, between explanation and ontology? Which, if any, conccpt of reduction is applicable to connectionist systems? What kind of legitinrtcy can the constructs of common sense psychology, or of that vclsion ol intentional realism represented by classical symbol-systems n I, hirvc irr ir full-scale connectionist theory of mind? (shrink)

Este artículo tiene como objetivo exponer algunas de las principales cuestiones que se debaten bajo el término de multiculturalismo en el marco de un contexto político de gran amplitud. Se centra tanto en el tema de las minorías nacionales y sus demandas de autonomía política como en las minorías étnicas inmigrantes y su establecimiento en el seno de los Estados de acogida. Ambos tipos de minorías son percibidos como fuente de problemas en la Europa Occidental, el sudeste de Europa y (...) la antigua Unión Soviética y los debates que emergen en cada una de estas zonas geográficas impactan sobre su gestión y gobierno en el resto de las áreas mencionadas. Por último, se reconoce que la naturaleza del debate ha sufrido un gran cambio como consecuencia del actual liderazgo estadounidense en la lucha contra el terrorismo. (shrink)

This paper is a commentary on the target article by Lokendra Shastri & Venkat Ajjanagadde [S&A]: “From simple associations to systematic reasoning: A connectionist representation of rules, variables and dynamic bindings using temporal synchrony” in same issue of the journal, pp.417–451. -/- It puts S&A's temporal-synchrony binding method in a broader context, comments on notions of pointing and other ways of associating information - in both computers and connectionist systems - and mentions types of reasoning that are a challenge to (...) S&A's system (amongst many other connectionist systems, recognizing that S&A's is much more capable as regards reasoning than most other contemporary systems). (shrink)

Clearly we can perceive both objects, and various aspects or appearances of those objects. But how should that complexity of perceptual content be explained or analyzed? I argue that perceptual representations normally have a double or two level nested structure of content, so as to adequately incorporate information both about contextual aspects Y(X) of an object X, and about the object X itself. On this double content (DC) view, perceptual processing starts with aspectual data Y?(X?) as a higher level of (...) content, which data does not itself provide lower level X-related content, but only an aspectually encoded form of such data. Hence the relevant perceptual data Y?(X?) must be. (shrink)

Memory is studied at a bewildering number of levels, with a vast array of methods, and in a daunting range of disciplines and subdisciplines. Is there any sense in which these various memory theorists – from neurobiologists to narrative psychologists, from the computational to the cross-cultural – are studying the same phenomena? In this exploratory position paper, I sketch the bare outline of a positive framework for understanding current work on constructive remembering, both within the various cognitive sciences, and across (...) gulfs between the cognitive and the social sciences. I pinpoint some lines of psychological theory and research which offer promising and compatible ways of thinking about individual memory and shared or social memory simultaneously. These are obviously ambitious projects, and this paper seeks more to elicit help with forging these connections than to present firm results. The aim is to draw out some consequences of empirical work on social memory and in developmental psychology. (shrink)

The paper is a commentary on the target article by Christine A. Skarda & Walter J. Freeman, “How brains make chaos in order to make sense of the world”, in the same issue of the journal, pp.161–195. -/- I confine my comments largely to some philosophical claims that Skarda & Freeman make and to the relationship of their model to connectionism. Some of the comments hinge on what symbols are and how they might sit in neural systems.

This paper is a commentary on the target article by Dana H. Ballard, “Cortical connections and parallel processing: Structure and function”, in the same issue of the journal, pp. 67–120. -/- I raise some issues about the connectionist or neural-network implementation of information and information processing. Issues include the sharing of information by different parts of a connectionist/neural network, the copying of complex information from one place to another in a network, the possibility of connection weights not being synaptic weights, (...) and the possibility of fast communication within single neurons as complex systems in their own right. (shrink)

The key problem for normative (or moral) cultural relativism arises as soon as we try to formulate it. It resists formulations that are (1) clear, precise, and intelligible; (2) plausible enough to warrant serious attention; and (3) faithful to the aims of leading cultural relativists, one such aim being to produce an important alternative to moral universalism. Meeting one or two of these conditions is easy; meeting all three is not. I discuss twenty-four candidates for the label "cultural relativism," showing (...) that not one meets all three conditions. In the end I conclude that cultural relativists have produced nothing that threatens universalism. (shrink)

This paper is a commentary on the target article by Michael Arbib, “Levels of modeling of mechanisms of visually guided behavior”, in the same issue of the journal, pp. 407–465. -/- I focus on the importance of the inclusion of an ability of a system to entertain, at a given time, multiple instantiations of a given schema (situation template, frame, script, action plan, etc.), and complications introduced into neural/connectionist network systems by such inclusion.

A book Review of Artificial Knowing Gender and the Thinking Machine, by Alison Adam, Routledge: Taylor and Francis, 1998.

The category of works of fiction is a very broad and heterogeneous one. I do have a general thesis in mind about such works, namely, that they themselves are fictional, in much the same way as are the fictional events or entities that they are about. But a defense of such a broad thesis would provide an intractably complex topic for an introductory essay, so I shall here confine myself to a presentation of a similar thesis for narrative theatrical works (...) or plays, performances of which are naturally regarded as involving, or evoking, a “fictional world” whose fictional characters and events are what the work in question is about. Another reason for initially focusing on such narrative plays is because performances of them provide a rich source of epistemic issues about evidence for artistic authenticity or correctness of artworks, which will turn out to be of integral importance to my fictionalist account of plays. (shrink)

The representational content or subject matter of a picture is normally distinguished from various non-representational components of meaning involved in artworks, such as expressive, stylistic or intentional factors. However, I show how such non subject matter components may themselves be analyzed in content terms, if two different categories of representation are recognized--aspect indication for stylistic etc. factors, and normal representation for subject matter content. On the account given, the relevant kinds of content are hierarchically structured, with relatively unconceptualized lower level (...) aspectual contents encoding or symbolizing higher level conceptualized representational subject matter. Such an account is strongly supported by the latest findings of cognitive science regarding levels of conceptualization. The paper also demonstrates how the account given is compatible with the actual pictorial competence of normal viewers of visual artworks. (shrink)