Vaccination can protect vaccinated individuals and often also prevent them from spreading disease to other people. This opens up the possibility of getting vaccinated for the sake of others. In fact, altruistic vaccination has recently been conceptualized as a kind of vaccination that is undertaken primary for the benefit of others. In order to better understand the potential role of altruistic motives in people’s vaccination decisions, we conducted two focus group studies with a total of 37 participants. Study 1 included (...) three focus groups on the subject of HPV vaccination for boys. Study 2 included three focus groups on the subject of pertussis and measles vaccination for childcare workers. We found substantial evidence of other-regarding motives across all focus groups, which suggests that altruistic motives could be an important factor when it comes to people’s vaccination decisions. We address the significance of these findings for vaccination policy surrounding HPV vaccination for boys and vaccination for childcare workers. We also extend the findings to normative work on vaccination for the sake of others more generally. (shrink)

When consumers choose to abstain from purchasing meat, they face some uncertainty about whether their decisions will have an impact on the number of animals raised and killed. Consequentialists have argued that this uncertainty should not dissuade consumers from a vegetarian diet because the “expected” impact, or average impact, will be predictable. Recently, however, critics have argued that the expected marginal impact of a consumer change is likely to be much smaller or more radically unpredictable than previously thought. This objection (...) to the consequentialist case for vegetarianism is known as the “causal inefficacy” (or “causal impotence”) objection. In this paper, we argue that the inefficacy objection fails. First, we summarize the contours of the objection and the standard “expected impact” response to it. Second, we examine and rebut two contemporary attempts (by Mark Budolfson and Ted Warfield) to defeat the expected impact reply through alleged demonstrations of the inefficacy of abstaining from meat consumption. Third, we argue that there are good reasons to believe that single individual consumers—not just individual consumers taken as an aggregate—really do make a positive difference when they choose to abstain from meat consumption. Our case rests on three economic observations: (i) animal producers operate in a highly competitive environment, (ii) complex supply chains efficiently communicate some information about product demand, and (iii) consumers of plant-based meat alternatives have positive consumption spillover effects on other consumers. (shrink)

Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...) of an effective comparison and integration across domains, and for assessing whether or not to use functional diversity approaches for developing ecological management strategies. The objective of this contribution is to identify and critically analyze the most salient of these assumptions. To this aim, we provide an “epistemic roadmap” that pinpoints these assumptions along a set of historical, conceptual, empirical, theoretical, and normative dimensions. (shrink)

Significant associations have been found between specific human leukocyte antigen (HLA) alleles and organ transplant rejection, autoimmune disease development, and the response to infection. Traditional searches for disease associations have conventionally measured risk associated with the presence of individual HLA alleles. However, given the high level of HLA polymorphism, the pattern of amino acid variability, and the fact that most of the HLA variation occurs at functionally important sites, it may be that a combination of variable amino acid sites shared (...) by several alleles (shared epitopes) are better descriptors of the actual causative genetic variants. Here we describe a novel approach to genetic association analysis in which genes/proteins are broken down into smaller sequence features and then variant types defined for each feature, allowing for independent analysis of disease association with each sequence feature variant type. We have used this approach to analyze a cohort of systemic sclerosis patients and show that a sequence feature composed of specific amino acid residues in peptide binding pockets 4 and 7 of HLA-DRB1 explains much of the molecular determinant of risk for systemic sclerosis. (shrink)

PLEASE NOTE: This is the corrected 2nd eBook edition, 2021. ●●●●● _Critique of Impure Reason_ has now also been published in a printed edition. To reduce the otherwise high price of this scholarly, technical book of nearly 900 pages and make it more widely available beyond university libraries to individual readers, the non-profit publisher and the author have agreed to issue the printed edition at cost. ●●●●● The printed edition was released on September 1, 2021 and is now available through (...) all booksellers, including Barnes & Noble, Amazon, and brick-and-mortar bookstores under ISBN 978-0-578-88646-6. ●●●●● In light of the length of this book, readers who would like to have a more detailed description of the book's objectives and method may find it helpful to read the detailed and clearly written Wikipedia entry about this work: From the Wikipedia search page, use the search phrase "Critique of Impure Reason". At least at the time of this writing (11/29/2021), the Wikipedia entry is well-researched and accurate. ●●●●● In addition, a "Primer on Bartlett's CRITIQUE OF IMPURE REASON" has been made available by the author. It is available under its title through PhilPapers and other philosophy online archives. ●●●●● COMMENDATIONS OF THIS WORK, from the back cover of the published edition: ●●●●● “I admire its range of philosophical vision.” – Nicholas Rescher, Distinguished University Professor of Philosophy, University of Pittsburgh, author of more than 100 books. ●●●●● “Bartlett’s _Critique of Impure Reason_ is an impressive, bold, and ambitious work. Careful scholarship is balanced by original analyses that lead the reader to recognize the limits of meaning, knowledge, and conceptual possibility. The work addresses a host of traditional philosophical problems, among them the nature of space, time, causality, consciousness, the self, other minds, ontology, free will and determinism, and others. The book culminates in a fascinating and profound new understanding of relativity physics and quantum theory.” – Gerhard Preyer, Professor of Philosophy, Goethe-University, Frankfurt am Main, Germany, author of many books including _Concepts of Meaning_, _Beyond Semantics and Pragmatics_, _Intention and Practical Thought_, and _Contextualism in Philosophy_. ●●●●● “[This work’s] goal is of a unique and difficult species: Dr. Bartlett seeks to develop a formal logical calculus on the basis of transcendental philosophical arguments; in fact, he hopes that this calculus will be the formal expression of the transcendental foundation of knowledge.... I consider Dr. Bartlett’s work soundly conceived and executed with great skill.” – C. F. von Weizsäcker, philosopher and physicist, former Director, Max-Planck-Institute, Starnberg, Germany. ●●●●● “Bartlett has written an American “Prolegomena to All Future Metaphysics.” He aims rigorously to eliminate meaningless assertions, reach bedrock, and place philosophy on a firm foundation that will enable it, like science and mathematics, to produce lasting results that generations to come can build on. This is a great book, the fruit of a lifetime of research and reflection, and it deserves serious attention.” — Martin X. Moleski, former Professor, Canisius College, Buffalo, NY, studies of scientific method, the presuppositions of thought, and the self-referential nature of epistemology. ●●●●● “Bartlett has written a book on what might be called the underpinnings of philosophy. It has fascinating depth and breadth, and is all the more striking due to its unifying perspective based on the concepts of reference and self-reference.” – Don Perlis, Professor of Computer Science, University of Maryland, author of numerous publications on self-adjusting autonomous systems and philosophical issues concerning self-reference, mind, and consciousness. ●●●●● ●●●●● The _Critique of Impure Reason: Horizons of Possibility and Meaning_ comprises a major and important contribution to philosophy. Thanks to the generosity of its publisher, this massive 885-page volume has been published as a free open access eBook (3.75MB) as well as an open access printed edition. It inaugurates a revolutionary paradigm shift in philosophical thought by providing compelling and long-sought-for solutions to a wide range of philosophical problems. In the process, the work fundamentally transforms the way in which the concepts of reference, meaning, and possibility are understood. The book includes a Foreword by the celebrated German philosopher and physicist Carl Friedrich von Weizsäcker. ●●●●● In Kant’s _Critique of Pure Reason_ we find an analysis of the preconditions of experience and of knowledge. In contrast, but yet in parallel, the new _Critique_ focuses upon the ways—unfortunately very widespread and often unselfconsciously habitual—in which many of the concepts that we employ _conflict_ with the very preconditions of meaning and of knowledge. ●●●●● This is a book about the boundaries of frameworks and about the unrecognized conceptual confusions in which we become entangled when we attempt to transgress beyond the limits of the possible and meaningful. We tend either not to recognize or not to accept that we all-too-often attempt to trespass beyond the boundaries of the frameworks that make knowledge possible and the world meaningful. ●●●●● The _Critique of Impure Reason_ proposes a bold, ground-breaking, and startling thesis: that a great many of the major philosophical problems of the past can be solved through the recognition of a viciously deceptive form of thinking to which philosophers as well as non-philosophers commonly fall victim. For the first time, the book advances and justifies the criticism that a substantial number of the questions that have occupied philosophers fall into the category of “impure reason,” violating the very conditions of their possible meaningfulness. ●●●●● The purpose of the study is twofold: first, to enable us to recognize the boundaries of what is referentially forbidden—the limits beyond which reference becomes meaningless—and second, to avoid falling victims to a certain broad class of conceptual confusions that lie at the heart of many major philosophical problems. As a consequence, the boundaries of _possible meaning_ are determined. ●●●●● Bartlett, the author or editor of more than 20 books, is responsible for identifying this widespread and delusion-inducing variety of error, _metalogical projection_. It is a previously unrecognized and insidious form of erroneous thinking that undermines its own possibility of meaning. It comes about as a result of the pervasive human compulsion to seek to transcend the limits of possible reference and meaning. ●●●●● Based on original research and rigorous analysis combined with extensive scholarship, the _Critique of Impure Reason_ develops a self-validating method that makes it possible to recognize, correct, and eliminate this major and pervasive form of fallacious thinking. In so doing, the book provides at last provable and constructive solutions to a wide range of major philosophical problems. ●●●●● CONTENTS AT A GLANCE ▪▪▪▪▪ Preface ▪▪▪▪▪ Foreword by Carl Friedrich von Weizsäcker ▪▪▪▪▪ Acknowledgments ▪▪▪▪▪ Avant-propos: A philosopher’s rallying call ▪▪▪▪▪ Introduction ▪▪▪▪▪ A note to the reader ▪▪▪▪▪ A note on conventions ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART I ▪▪▪▪▪ ▪▪▪▪▪ WHY PHILOSOPHY HAS MADE NO PROGRESS AND HOW IT CAN ▪▪▪▪▪ 1 Philosophical-psychological prelude ▪▪▪▪▪ 2 Putting belief in its place: Its psychology and a needed polemic ▪▪▪▪▪ 3 Turning away from the linguistic turn: From theory of reference to metalogic of reference ▪▪▪▪▪ 4 The stepladder to maximum theoretical generality ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART II ▪▪▪▪▪ THE METALOGIC OF REFERENCE ▪▪▪▪▪ A New Approach to Deductive, Transcendental Philosophy ▪▪▪▪▪ 5 Reference, identity, and identification ▪▪▪▪▪ 6 Self-referential argument and the metalogic of reference ▪▪▪▪▪ 7 Possibility theory ▪▪▪▪▪ 8 Presupposition logic, reference, and identification ▪▪▪▪▪ 9 Transcendental argumentation and the metalogic of reference ▪▪▪▪▪ 10 Framework relativity ▪▪▪▪▪ 11 The metalogic of meaning ▪▪▪▪▪ 12 The problem of putative meaning and the logic of meaninglessness ▪▪▪▪▪ 13 Projection ▪▪▪▪▪ 14 Horizons ▪▪▪▪▪ 15 De-projection ▪▪▪▪▪ 16 Self-validation ▪▪▪▪▪ 17 Rationality: Rules of admissibility ▪▪▪▪▪ ▪▪▪▪▪ ▪▪▪▪▪ PART III ▪▪▪▪▪ PHILOSOPHICAL APPLICATIONS OF THE METALOGIC OF REFERENCE ▪▪▪▪▪ Major Problems and Questions of Philosophy and the Philosophy of Science ▪▪▪▪▪ 18 Ontology and the metalogic of reference ▪▪▪▪▪ 19 Discovery or invention in general problem-solving, mathematics, and physics ▪▪▪▪▪ 20 The conceptually unreachable: “The far side” ▪▪▪▪▪ 21 The projections of the external world, things-in-themselves, other minds, realism, and idealism ▪▪▪▪▪ 22 The projections of time, space, and space-time ▪▪▪▪▪ 23 The projections of causality, determinism, and free will ▪▪▪▪▪ 24 Projections of the self and of solipsism ▪▪▪▪▪ 25 Non-relational, agentless reference and referential fields ▪▪▪▪▪ 26 Relativity physics as seen through the lens of the metalogic of reference ▪▪▪▪▪ 27 Quantum theory as seen through the lens of the metalogic of reference ▪▪▪▪▪ 28 Epistemological lessons learned from and applicable to relativity physics and quantum theory ▪▪▪▪▪ ▪▪▪▪▪ PART IV ▪▪▪▪▪ HORIZONS ▪▪▪▪▪ 29 Beyond belief ▪▪▪▪▪ 30 _Critique of Impure Reason_: Its results in retrospect ▪▪▪▪▪ ▪▪▪▪▪ SUPPLEMENT ▪▪▪▪▪ The Formal Structure of the Metalogic of Reference ▪▪▪▪▪ APPENDIX I ▪▪▪▪▪ The Concept of Horizon in the Work of Other Philosophers ▪▪▪▪▪ APPENDIX II ▪▪▪▪▪ Epistemological Intelligence ▪▪▪▪▪ References ▪▪▪▪▪ Index ▪▪▪▪▪ About the author. 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This paper attempts to illuminate and interpret the contradictory portrait of God as both seen and unseen in the Torah. Thus Moses is commanded not to look on the face of God yet also praised for having spoken to God “face to face". We seek ways to reconcile the contradictory portraits of God through the use of the term “doubled-mindedness” in the theology of Jerome Gellman, in the logic of “thirdness” in C.S. Peirce’s semiotics, and in the use of both (...) particle and wave models in Einstein’s physics of light. The paper concludes by disusing the practical consequences of theological double-mindedness for the religious life and the philosophical meaning of redemption as the time when the contradiction of the unseen and seen God is resolved. (shrink)

Exploration of holy imagination -- touching upon areas of spirituality, time, reality, soul, religion, scripture, memory, poetry, Shlomo Carlebach... (c) 2015 Steven L. Maimes.

In this paper, I offer an account of our knowledge of other minds based on V. C. Aldrich's account of aesthetic perception, according to which there is a sense in which we literally see other minds.

Effects of perceived control and close alternative outcomes were examined. Subjects played a computer-simulated "wheel-of-fortune" game with another player in which two wheels spun simultaneously. Subjects had either control over spinning the wheel or control over which wheel would determine their outcome and which would determine the other player's outcome. Results showed that (a) subjects generated counterfactuals about the aspect of the game that they controlled, (b) the direction of these counterfactuals corresponded to the close outcome associated with the aspect (...) they controlled, and (c) close counterfactuals predicted affective responses to the outcome of the wheel spin. Cognitive and motivational implications of the influence of perceived control on counterfactual generation are discussed. (shrink)

This essay pertains to Nietzsche's and Spinoza's philosophical/historical relationship, and the hitherto unnoticed role Kant plays as an intermediary for Spinoza's ideas and legacy. We advance two main assertions: 1) that Nietzsche is historically related to Spinoza via Kant's Antinomies of Pure Reason and their legacy, and 2) that both the striking similarities and tremendous differences between these two thinkers are best described with reference to the Antithesis positions of Kant's Antinomies. Our account rests primarily on the works of two (...) other scholars. The first is Omri Boehm, who argues convincingly that a) Spinoza was both the single greatest influence on and primary target of Kant's Antinomies, and b) that Spinoza's position is remarkably similar to the first three Antithesis positions (and no other relevant thinker comes close). The second is Michael Steven Green, who argues with equal force that c) Nietzsche's mature philosophy is heavily dependent upon Afrikan Spir's concept of the "fundamental antinomy," and d) that Nietzsche's view of empirical reality amounts to an "antithetic" view of reality. We demonstrate that these two scholars were, independently of one other, pointing to a single historical/philosophical connection between Nietzsche and Spinoza, and begin an exploration of the ramifications of this discovery. (shrink)

Different sort of people are interested in personal identity. Philosophers frequently ask what it takes to remain oneself. Caregivers imagine their patients’ experience. But both philosophers and caregivers think from the armchair: they can only make assumptions about what it would be like to wake up with massive bodily changes. Patients with a locked-in syndrome (LIS) suffer a full body paralysis without cognitive impairment. They can tell us what it is like. Forty-four chronic LIS patients and 20 age-matched healthy medical (...) professionals answered a 15-items questionnaire targeting: (A) global evaluation of identity, (B) body representation and (C) experienced meaning in life. In patients, selfreported identity was correlated with B and C. Patients differed with controls in C. These results suggest that the paralyzed body remains a strong component of patients’ experienced identity, that patients can adjust to objectives changes perceived as meaningful and that caregivers fail in predicting patients’ experience. (shrink)

This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.

Je commence par quelques commentaires célèbres par le philosophe (psychologue) Ludwig Wittgenstein parce que Pinker partage avec la plupart des gens (en raison des paramètres par défaut de notre psychologie innée évoluée) certains préjugés sur le fonctionnement de l’esprit, et parce que Wittgenstein offre des idées uniques et profondes dans le fonctionnement du langage, la pensée et la réalité (qu’il considérait comme plus ou moins coextensive) ne trouve nulle part ailleurs. Lare est seulement une référence à Wittgenstein dans ce volume, (...) ce qui est très malheureux étant donné qu’il était l’analyste le plus brillant et original de la langue. Dans le dernier chapitre, en utilisant la célèbre métaphore de la grotte de Platon, il résume magnifiquement le livre avec un aperçu de la façon dont l’esprit (langage, pensée, psychologie intentionnelle) - un produit de l’égoïsme aveugle, modéré que légèrement par l’altruisme automatisé pour les proches portant des copies de nos gènes (Inclusive Fitness)- fonctionne automatiquement, mais tente de se terminer sur une note optimiste en nous donnant l’espoir que nous pouvons néanmoins utiliser ses vastes capacités pour coopérer et faire du monde un endroit décent pour vivre. Pinker est certainement au courant, mais dit peu sur le fait que beaucoup plus sur notre psychologie est laissé de côté que inclus. Parmi les fenêtres de la nature humaine qui sont laissées de côté ou qui reçoivent un minimum d’attention, on peut lire les mathématiques et la géométrie, la musique et les sons, les images, les événements et la causalité, l’ontologie (classes de choses ou ce que nous savons), la plupart de l’épistémologie (comment nous le savons), les dispositions (croire, penser, juger, avoir l’intention, etc.) et le reste de la psychologie intentionnelle de l’action, des neurotransmetteurs et des enthéogènes, des états spirituels (p. ex. satori et illumination, stimulation et enregistrement du cerveau, lésions cérébrales et déficits comportementaux et troubles, jeux et sports, théorie de la décision (théorie des jeux et économie comportementale), comportement animal (très peu de langage mais un milliard d’années de génétique partagée). De nombreux livres ont été écrits sur chacun de ces domaines de la psychologie intentionnelle. Les données de ce livre sont des descriptions, pas des explications qui montrent pourquoi notre cerveau le fait de cette façon ou comment il est fait. Comment pouvons-nous utiliser les phrases de leur manière (c.-à-d., connaître toutes leurs significations)? Il s’agit d’une psychologie évolutive qui fonctionne à un niveau plus fondamental, c’est-à-dire le niveau où Wittgenstein est le plus actif. Et il y a peu d’attention au contexte dans lequel les mots sont utilisés - une arène que Wittgenstein a lancée. Néanmoins, il s’agit d’une oeuvre classique et avec ces mises en garde est encore bien la peine de lire. Ceux qui souhaitent un cadre complet à jour pour le comportement humain de la vue moderne de deuxemssyst peuvent consulter mon livre 'The Logical Structure of Philosophy, Psychology, Mind and Language in Ludwig Wittgenstein and John Searle' 2nd ed (2019). Ceux qui s’intéressent à plus de mes écrits peuvent voir «Talking Monkeys --Philosophie, Psychologie, Science, Religion et Politique sur une planète condamnée --Articles et revues 2006-2019 3e ed (2019) et Suicidal Utopian Delusions in the 21st Century 4th ed (2019) et autres. (shrink)

Ce n’est pas un livre parfait, mais il est unique, et si vous écrémez les 400 premières pages ou plus, les 300 dernières (sur quelque 700) sont une assez bonne tentative d’appliquer ce qui est connu sur le comportement aux changements sociaux de la violence et des manières au fil du temps. Le sujet fondamental est le suivant : comment notre génétique contrôle-t-elle et limite-t-elle le changement social ? Étonnamment, il ne parvient pas à décrire la nature de la sélection (...) des parents (fitness inclusif) qui explique une grande partie de la vie sociale animale et humaine. Il n’a pas non plus (comme presque tout le monde) un cadre clair pour décrire la structure logique de la rationalité (LSR—terme préféré de John Searle) que je préfère appeler la psychologie descriptive de la pensée de haut ordre (DPHOT). Il aurait dû dire quelque chose sur les nombreuses autres façons d’abuser et d’exploiter les gens et la planète, car ceux-ci sont maintenant beaucoup plus graves que de rendre d’autres formes de violence presque hors de propos. Étendre le concept de violence pour inclure les-conséquences mondiales à long terme de la réplication des gènes de quelqu’un, et avoir une compréhension de la nature de la façon dont fonctionne l’évolution (c.-à-d., la sélection des parents) fournira une perspective très différente sur l’histoire, les événements actuels, et comment les choses sont susceptibles d’aller dans les quelques centaines d’années. On pourrait commencer par noter que la diminution de la violence physique au cours de l’histoire a été compensée (et rendue possible) par le viol sans pitié de la planète (c’est-à-dire par la destruction par les gens de l’avenir de leur propre descendant). Pinker (comme la plupart des gens la plupart du temps) est souvent distrait par les superficialités de la culture quand c’est la biologie qui compte. Voir mes critiques récentes de Wilson 'The Social Conquest of Earth' et Nowak and Highfield’s 'SuperCooperators' ici et sur le net pour un bref résumé de la vacuité de «véritable altruisme»(sélection de groupe), et le fonctionnement de la sélection des parents et l’inutilité et la superficialité de décrire le comportement en termes culturels. C’est la question classique de la nature/nourrir et la nature l’emporte nourrir - infiniment. Ce qui importe vraiment, c’est la violence faite à la terre par l’augmentation incessante de la population et de la destruction des ressources (en raison de la médecine et de la technologie et de la répression des conflits par la police et l’armée). Environ 200.000 personnes de plus par jour (un autre Las Vegas tous les 10 jours, un autre Los Angeles chaque mois), les 6 tonnes ou plus de la base va dans la mer / personne / année - environ 1% du total du monde disparaissant chaque année, etc. signifie que si un miracle se produit la biosphère et la civilisation va largement s’effondrer au cours des deux prochains siècles, et il y aura la famine, la misère et la violence de tous les types. Les manières, les opinions et les tendances des gens à commettre des actes de violence ne sont d’aucune pertinence à moins qu’ils ne puissent faire quelque chose pour éviter cette catastrophe, et je ne vois pas comment cela va se produire. Il n’y a pas de place pour les arguments, et aucun point non plus (oui je suis un fataliste), donc je vais juste faire quelques commentaires comme s’ils étaient des faits. N’imaginez pas que j’ai un intérêt personnel dans la promotion d’un groupe au détriment des autres. J’ai 78, n’ont pas de descendants et pas de proches parents et ne s’identifient à aucun groupe politique, national ou religieux et considèrent ceux que j’appartiens par défaut aussi répugnant que tout le reste. Les parents sont les pires ennemis de la vie sur Terre et, compte tenu de la vue générale des choses, les femmes sont aussi violentes que les hommes quand on considère le fait que la violence des femmes (comme la plupart de celle faite par les hommes) se fait en grande partie au ralenti, à une distance dans le temps et l’espace et la plupart du temps effectuée par procuration -par leurs descendants et par les hommes. De plus en plus, les femmes portent des enfants, qu’elles aient un compagnon ou non et que l’effet d’empêcher une femme de se reproduire est en moyenne beaucoup plus important que d’arrêter un homme, car ils constituent le goulot d’étranglement reproducteur. On peut considérer que les gens et leur progéniture méritent richement toute la misère vient leur chemin et (à de rares exceptions près) les riches et les célèbres sont les pires délinquants. Meryl Streep ou Bill Gates ou J.K Rowling et chacun de leurs enfants peuvent détruire 50 tonnes de terre d’o re plus chaque année pendant des générations dans l’avenir, tandis qu’un fermier indien et son peut détruire 1 tonne. Si quelqu’un nie que c’est très bien, et à leurs descendants, je dis "Bienvenue à l’enfer sur Terre"(WTHOE). Aujourd’hui, l’accent est toujours mis sur les droits de l’homme, mais il est clair que si la civilisation doit avoir une chance, les responsabilités humaines doivent remplacer les droits de l’homme. Personne n’obtient des droits sans être un citoyen responsable et la première chose que cela signifie est la destruction de l’environnement minimal. La responsabilité la plus fondamentale n’est pas les enfants à moins que votre société vous demande de les produire. Une société ou un monde qui permet aux gens de se reproduire au hasard sera toujours exploité par des gènes égoïstes jusqu’à ce qu’il s’effondre (ou atteint un point où la vie est si horrible qu’il ne vaut pas la peine de vivre). Si la société continue à maintenir les droits de l’homme comme primaires, à leurs descendants, on peut dire avec confiance "WTHOE". Ceux qui souhaitent un cadre complet à jour pour le comportement humain de la vue moderne de deuxemssyst peuvent consulter mon livre 'The Logical Structure of Philosophy, Psychology, Mind and Language in Ludwig Wittgenstein and John Searle' 2nd ed (2019). Ceux qui s’intéressent à plus de mes écrits peuvent voir «Talking Monkeys --Philosophie, Psychologie, Science, Religion et Politique sur une planète condamnée --Articles et revues 2006-2019 3e ed (2019) et Suicidal Utopian Delusions in the 21st Century 4th ed (2019) et autres. (shrink)

Comincio con alcuni commenti famosi del filosofo (psicologo) Ludwig Wittgenstein perché Pinker condivide con la maggior parte delle persone (a causa delle impostazioni predefinite della nostra psicologia innata evoluta) certi pregiudizi sul funzionamento della mente, e perché Wittgenstein offre approfondimenti unici e profondi sul funzionamento del linguaggio, del pensiero e della realtà (che ha visto come più o meno coetantana) non trovati altrove. Ilre è solo riferimento a Wittgenstein in questo volume, che è più sfortunato considerando che era il più (...) brillante e originale analista del linguaggio. Nell'ultimo capitolo, utilizzando la famosa metafora della grotta di Platone, riassume splendidamente il libro con una panoramica di come la mente (linguaggio, pensiero, psicologia intenzionale) – un prodotto di egoismo cieco, moderato solo leggermente da altruismo automatizzato per parenti stretti che trasportano copie dei nostri geni (Inclusive Fitness)- funziona automaticamente, ma cerca di finire in una nota ottimista dandoci la speranza che possiamo comunque impiegare le sue vaste capacità di cooperare e rendere il mondo un posto dignitoso. Pinker è certamente a conoscenza, ma dice poco sul fatto che molto di più sulla nostra psicologia è lasciato fuori di quanto incluso. Tra le finestre della natura umana che vengono lasciate fuori o che richiedono un'attenzione minima ci sono la matematica e la geometria, la musica e i suoni, le immagini, gli eventi e la causalità, l'ontologia (classi di cose o ciò che sappiamo), la maggior parte dell'epistemologia (come lo conosciamo), disposizioni (credenti, pensare, giudicare, intendere ecc.) e il resto della psicologia intenzionale dell'azione, neurotrasmettitori ed espiogeni, stati spirituali (ad esempio, satori e illuminazione, stimolazione e registrazione cerebrale, danni cerebrali e disturbi comportamentali, giochi e sport, teoria delle decisioni (inclusi la teoria dei giochi e l'economia comportamentale), il comportamento animale (molto poco linguaggio ma un miliardo di anni di errori genetici condivisi). Molti libri sono stati scritti su ognuna di queste aree della psicologia intenzionale. I dati di questo libro sono descrizioni, non spiegazioni che mostrano perché i nostri cervelli lo fanno in questo modo o come viene fatto. Come facciamo a sapere di usare le frasi nel loro modo diverso (cioè, conoscere tutti i loro significati)? Questa è la psicologia evolutiva che opera a un livello più elementare – il livello in cui Wittgenstein è più attivo. E c'è una particolare attenzione al contesto in cui vengono usate le parole, un'arena che Wittgenstein ha aperto la strada. Tuttavia, questo è un lavoro classico e con queste precauzioni è ancora ben vale la pena leggere. Coloro che desiderano un quadro aggiornato completo per il comportamento umano dalla moderna vista a due systems possono consultare il mio libro 'La struttura logica dellafilosofia, psicologia, Mind e il linguaggio in Ludwig Wittgenstein e John Searle' 2nd ed (2019). Coloro che sono interessati a più dei miei scritti possono vedere 'TalkingMonkeys--Filosofia, Psicologia, Scienza, Religione e Politica su un Pianeta Condannato--Articoli e Recensioni 2006-2019 3rd ed (2019) e Suicidal Utopian Delusions nel 21st Century 4th ed (2019) . (shrink)

Questo non è un libro perfetto, ma è unico, e se scorri le prime 400 pagine o giù di lì, le ultime 300 (circa 700) sono un buon tentativo di applicare ciò che è noto sul comportamento ai cambiamenti sociali nella violenza e nelle maniere nel tempo. L'argomento di base è: come fa la nostra genetica a controllare e limitare il cambiamento sociale? Sorprendentemente non riesce a descrivere la natura della selezione dei parenti (idoneità inclusiva) che spiega gran parte della (...) vita sociale animale e umana. Egli manca anche (come quasi tutti) manca di un quadro chiaro per descrivere la struttura logica della razionalità (termine preferito di John Searle) che preferisco chiamare la Psicologia descrittiva del Pensiero dell'Ordine Superiore (DPHOT). Avrebbe dovuto dire qualcosa sui molti altri modi di abusare e sfruttare le persone e il pianeta, dal momento che questi sono ora molto più gravi da rendere quasi irrilevanti altre forme di violenza. Estendere il concetto di violenza per includere leconseguenze globali a lungoterminedella replicazione dei geni diqualcuno, e avere una comprensione della natura di come funziona l'evoluzione (cioè la selezione dei parenti) fornirà una prospettiva molto diversa sulla storia, gli eventi attuali e come le cose probabilmente andranno nei prossimi centinaia di anni. Si potrebbe iniziare notando che la diminuzione della violenza fisica nel corso della storia è stata abbinata (e resa possibile) dallo stupro spietato in costante aumento del pianeta (cioè dalla distruzione del futuro del proprio discendente).’ Pinker (come la maggior parte delle persone) è spesso distratto dalle superficialità della cultura quando è la biologia che conta. Guarda le mie recenti recensioni di Wilson 'The Social Conquest of Earth' e 'SuperCooperators' di Nowak e Highfield qui e in rete per un breve riassunto della vacuità del 'vero altruismo'(selezione di gruppo), e l'operazione di selezione dei parenti e l'inutilità e la superficialità di descrivere il comportamento in termini culturali. Questo è il classico problema della natura/nutrimento e la natura vince nutrita --infinitamente. Ciò che conta veramente è la violenza fatta sulla terra dall'incessante aumento della popolazione e della distruzione delle risorse (a causa della medicina e della tecnologia e della repressione dei conflitti da parte della polizia e dei militari). Circa 200.000 persone in più al giorno (un altro Las Vegas ogni 10 giorni, un'altra Los Angeles ogni mese), le 6 tonnellate o giù di lì di pisolino che vanno in mare / persona / anno – circa l'1% del totale del mondo che scompare ogni anno, ecc. significa che se qualche miracolo accadrà la biosfera e la civiltà crollerà in gran parte durante i prossimi due secoli, e ci sarà fame, violenza e violenza di ogni tipo su scala impressionante. Le maniere, le opinioni e le tendenze delle persone a commettere atti violenti non hanno alcuna importanza a meno che non possano fare qualcosa per evitare questa catastrofe, e non vedo come ciò accadrà. Non c'è spazio per gli argomenti, e nessun punto sia (sì io sono un fatalista), quindi mi limiterò a fare alcuni commenti come se fossero fatti. Non immaginate di avere un'informazione personale nel promuovere un gruppo a spese degli altri. Io sono 78, nonhanno discendenti e non hanno parenti stretti e non si identificano con alcun gruppo politico, nazionale o religioso e considerano quelli a cui appartengo di default come ripugnanti come tutti gli altri. I genitori sono i peggiori nemici della vita sulla Terra e, tenendo la vista generale delle cose, le donne sono violente come gli uomini se si considera il fatto che la violenza delle donne (come la maggior parte di quella fatta dagli uomini) è in gran parte fatta al rallentatore, a distanza nel tempo e nello spazio e per lo più effettuata per procura dai loro discendenti e dagli uomini. Sempre più spesso, le donne portano figli indipendentemente dal fatto che abbiano un compagno e l'effetto di impedire a una donna di riprodursi è in media molto maggiore dell'arresto di un uomo, poiché sono il collo di bottiglia riproduttivo. Si può ritenere che le persone e la loro prole meritino riccamente qualsiasi miseria arrivi la loro strada e (con rare eccezioni) i ricchi e famosi sono i peggiori trasgressori. Meryl Streep o Bill Gates o J.K Rowling e ognuno dei loro figli può distruggere 50 tonnellate di suolo ogni anno per generazioni nel futuro, mentre un contadino indiano e il suo possono distruggere 1 tonnellata. Se qualcuno nega che va bene, e ai loro discendenti dico "Benvenuti all'inferno sulla Terra" (WTHOE). Oggi l'accento è sempre posto sui diritti dell'uomo, ma è chiaro che se si vuole che la civiltà abbia una possibilità, le responsabilità umane devono sostituire i diritti umani. Nessuno ottiene diritti senza essere un cittadino responsabile e la prima cosa che ciò significa è ladistruzione ambientalemi nimal. La responsabilità più fondamentale non è quella dei bambini a meno che la vostra società non vi chieda di produrli. Una società o un mondo che permette alle persone di allevare a caso sarà sempre sfruttato dai geni egoisti fino a quando non crolla (o raggiunge un punto in cui la vita è così orribile che non vale la pena di vivere). Se la società continua a mantenerei diritti umani come primari, ai loro discendenti si può dire con fiducia "WTHOE". Coloro che desiderano un quadro aggiornato completo per il comportamento umano dalla moderna vista a due systems possono consultare il mio libro 'La struttura logica dellafilosofia, psicologia, Mind e il linguaggio in Ludwig Wittgenstein e John Searle' 2nd ed (2019). Coloro che sono interessati a più dei miei scritti possono vedere 'Talking Monkeys--Filosofia, Psicologia, Scienza, Religione e Politica su un Pianeta Condannato--Articoli e Recensioni 2006-2019 3rd ed (2019) e Suicidal Utopian Delusions nel 21st Century 4th ed (2019) . (shrink)

Response to Steven Bland’s ‘Interactionism, Debiasing, and the Division of Epistemic Labour’ (in Social Virtue Epistemology, (eds.) M. Alfano, C. Klein & J. de Ridder). Biased cognition is an obvious source of epistemic vice, but there is some controversy about whether cognitive biases generate reliabilist or responsibilist epistemic vices. Bland’s argument, in a nutshell, is that since the development of cognitive biases is due to the interplay of internal psychological processes and external (i.e., environmental) conditions, it cannot be expected (...) that a solution to the problem tackles only one of these dimensions. We argue that the complex architecture on which Bland’s coordinated approach is grounded appears to lose some stability once we analyze more closely its pillars. We shall concentrate our attention on the notion of reliabilist and responsibilist epistemic virtues that the approach should foster as well as on the educational implications of Bland’s view. (shrink)

With insights from philosophy of language and semiotics, this article addresses judicial choices and semantic errors involved in United States v. Stevens, 130 S.Ct. 1577 (2010) (refusing to read “killing” and “wounding” to include cruelty and thus striking down a federal statute outlawing videos of animal cruelty), and Snyder v. Phelps, 131 S.Ct. 1207 (2011) (finding a First Amendment right to picket military funerals and verbally attack parents of dead soldiers as part of purportedly-public expression). -/- This article maintains that (...) a better understanding of semiotics (the theory of signs) exposes the flaws in both decisions and bolsters the arguments of the lone dissenter in both cases, Justice Alito. Such a better understanding of semiotics involves grasping (a) how expression involves signs, (b) how signs work in general, and (c) the differences between three basic kinds of signs (indexes, icons and symbols). This article maintains that the expression involved in Stevens and in Phelps was a type of indexical or quasi-indexical expression that, for reasons similar to those involved in child pornography cases, should have no First Amendment protection. -/- This article also notes shifting interpretive positions in the Court that cry out for reform. Although Chief Justice Roberts uses a textualist approach in his majority opinion striking down the animal cruelty statute in Stevens, his majority opinion in National Federation of Independent Business v. Sebelius, 132 S.Ct. 2566 (2012), has no trouble finding a “penalty” a “tax,” upholding the Affordable Care Act, and chastising the dissent for voting to strike down a statute simply because “. . . Congress used the wrong labels.” Id. at 2597. -/- This article attempts to expose such gamesmanship in “textualism” and attempts to lay out a better semiotic path for the Court. It calls for more forthright judicial decision-making in constitutional and statutory interpretation; calls for rejecting mechanical notions of law that conceal judicial choice involved in constitutional and statutory interpretation; and calls for rejecting claims that dictionaries can settle constitutional or statutory interpretation issues without reference to constitutional and statutory goals. -/- Keywords: interpretation, construction, meaning, plain meaning, originalism, original intent, canon, semiotics, signs, signals, symbol, icon, index, signifier, signified, ordinary meaning, freedom of speech, freedom of expression, animal cruelty, first amendment, statutes. (shrink)

*Presented at the Western Canadian Philosophical Association Conference 2019 at the University of Lethbridge in Lethbridge, Alberta.* -/- This paper discusses some issues that arise when applying structural realism to biology. I begin by reviewing Katherine Brading’s version of structural realism with a hierarchy with proliferation of models.1 I then attempt to apply Brading’s structural realism to a biological example. This biological example suggests an issue with the use of shared structure. In response, I suggest the use of relevant relations (...) instead of shared structure. I then discuss Steven French’s use of eliminativist ontic structural realism in biology. Additionally, I consider John Dupré and Maureen A. O’Malley’s discussion of metagenomics and claim that biological entities are better described as self-sustaining biological processes.2 These metagenomic insights suggest an eliminativist view is preferable in biology. I conclude with an attempt to combine Brading’s and French’s approaches into an eliminativist relevant relationalism that retains the structuralist flavor and is applicable to the fluid, constantly changing entities found in biology. -/- 1. Katherine Brading, “Structuralist Approaches to Physics: Objects, Models and Modality,” chap. 3 in Scientific Structuralism, ed. Alisa Bokulich and Peter Bokulich, vol. 281, Boston Studies in the Philosophy of Science (Dordrecht: Springer Netherlands, 2011), 43–65, isbn: 9789048195978, doi:10.1007/978-90-481-9597-8_3. 2. John Dupré and Maureen A. O’Malley, “Metagenomics and biological ontology,” Studies in History and Philosophy of Biological and Biomedical Sciences 38 (2007): 84. (shrink)

Epistemic paternalism is the thesis that a paternalistic interference with an individual's inquiry is justified when it is likely to bring about an epistemic improvement in her. In this article I claim that in order to motivate epistemic paternalism we must first account for the value of epistemic improvements. I propose that the epistemic paternalist has two options: either epistemic improvements are valuable because they contribute to wellbeing, or they are epistemically valuable. I will argue that these options constitute the (...) foundations of a dilemma: either epistemic paternalism collapses into general paternalism, or a distinctive project of justified epistemic paternalism is implausible. (shrink)

Techniques from behavioral economics—nudges—may help physicians increase pediatric vaccine compliance, but critics have objected that nudges can undermine autonomy. Since autonomy is a centrally important value in healthcare decision-making contexts, it counts against pediatric vaccination nudges if they undermine parental autonomy. Advocates for healthcare nudges have resisted the charge that nudges undermine autonomy, and the recent bioethics literature illustrates the current intractability of this debate. This article rejects a principle to which parties on both sides of this debate sometimes seem (...) committed: that nudges are morally permissible only if they are consistent with autonomy. Instead, I argue that, at least in the case of pediatric vaccination, some autonomy-undermining nudges may be morally justified. This is because parental autonomy in pediatric decision-making is not as morally valuable as the autonomy of adult patients, and because the interests of both the vaccinated child and other members of the community can sometimes be weighty enough to justify autonomy-infringing pediatric vaccination nudges. This article concludes with a set of worries about the effect of pediatric vaccination nudges on parent-physician relationships, and it calls on the American Academy of Pediatrics to draw on scientific and bioethics research to develop guidelines for the use of nudges in pediatric practice and, in particular, for the use of pediatric vaccination nudges. (shrink)

Neo-Humean instrumentalist theories of reasons for acting have been presented with a dilemma: either they are normatively trivial and, hence, inadequate as a normative theory or they covertly commit themselves to a noninstrumentalist normative principle. The claimed result is that no purely instrumentalist theory of reasons for acting can be normatively adequate. This dilemma dissolves when we understand what question neo-Humean instrumentalists are addressing. The dilemma presupposes that neo-Humeans are attempting to address the question of how to act, 'simpliciter'. Instead, (...) they are evaluating actions from the agent's normative perspective. (shrink)

Some environmental ethicists and economists argue that attributing infinite value to the environment is a good way to represent an absolute obligation to protect it. Others argue against modelling the value of the environment in this way: the assignment of infinite value leads to immense technical and philosophical difficulties that undermine the environmentalist project. First, there is a problem of discrimination: saving a large region of habitat is better than saving a small region; yet if both outcomes have infinite value, (...) then decision theory prescribes indifference. Second, there is a problem of swamping probabilities: an act with a small but positive probability of saving an endangered species appears to be on par with an act that has a high probability of achieving this outcome, since both have infinite expected value. Our paper shows that a relative concept of infinite value can be meaningfully defined, and provides a good model for securing the priority of the natural environment while avoiding the failures noted by sceptics about infinite value. Our claim is not that the relative infinity utility model gets every detail correct, but rather that it provides a rigorous philosophical framework for thinking about decisions affecting the environment. (shrink)

Stewart Cohen argues that much contemporary epistemological theorizing is hampered by the fact that ‘epistemic justification’ is a term of art and one that is never given any serious explication in a non-tendentious, theory-neutral way. He suggests that epistemologists are therefore better off theorizing in terms of rationality, rather than in terms of ‘epistemic justification’. Against this, I argue that even if the term ‘epistemic justification’ is not broadly known, the concept it picks out is quite familiar, and partly because (...) it’s a term of art, justification talk is a better vehicle for philosophical theorizing. ‘Rational’ is too unclear for our philosophical purposes, and the fact that ‘epistemic justification’ gets fleshed out by appeal to substantive, controversial theses is no obstacle to its playing the needed role in epistemological theorizing. (shrink)

This chapter first surveys general issues in the epistemic internalism / externalism debate: what is the distinction, what motivates it, and what arguments can be given on both sides. -/- The second part of the chapter will examine the internalism / externalism debate as regards to the specific case of the epistemology of memory belief.

In two recent papers, Michael Della Rocca accuses Descartes of reasoning circularly in the Fourth Meditation. This alleged new circle is distinct from, and more vicious than, the traditional Cartesian Circle arising in the Third Meditation. We explain Della Rocca’s reasons for this accusation, showing that his argument is invalid.

Many countries are experiencing increasing levels of demand for access to assisted reproductive technologies. Policies regarding who can access ART and with what support from a collective purse are highly contested, raising questions about what state responses are justified. Whilst much of this debate has focused on the status of infertility as a disease, we argue that this is something of a distraction, since disease framing does not provide the far-reaching, robust justification for state support that proponents of ART seem (...) to suppose. Instead, we propose that debates about appropriate state responses should consider the various implications for health and broader well-being that may be associated with difficulties starting a family. We argue that the harms and disruption to valued life projects of subfertility-related suffering may provide a stronger basis for justifying state support in this context. Further, we suggest that, whilst ART may alleviate some of the harm resulting from subfertility, population-level considerations can indicate a broader range of interventions aimed at tackling different sources of subfertility-related harm, consistent with broader public health aims. (shrink)

NUTRIÇÃO SOBRE A AZOOSPERMIA EM BOVINOS -/- -/- E. I. C. da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim Departamento de Zootecnia – UFRPE sede -/- AZOOSPERMIA EM BOVINOS -/- INTRODUÇÃO -/- A falta completa de esperma no ejaculado pode ser devido a uma falha no processo de espermatogênese ou relacionada a causas no transporte do esperma. Com relação ao transporte, o esperma pode ser impedido de ser ejaculado mediante bloqueios ou oclusões no sistema do ducto extragonadal, ou (...) por causa de uma disfunção ejaculatória. Nos cães, por exemplo, a possibilidade de oclusão ser a causa pode ser determinada por medições de fosfatase alcalina (ALP) no plasma seminal, já que a ALP se origina do epidídimo e seminífero epitélio tubular. Se a concentração de ALP no fluido seminal for superior a 5000 UI/l, a amostra ejaculada contém fluido desses tecidos e a oclusão pode ser descartada. -/- As causas testiculares da azoospermia incluem a falha da espermatogênese, que pode ser causada por uma série de fatores; estes incluem fatores hormonais, imunológicos, congênitos, tóxicos, patogênicos, traumáticos e nutricionais. Aqui, as supressões na região do AZF (que contém sub-regiões AZFa, AZFb e AZFc) no cromossoma Y desempenham um papel importante, representando 10-15% dos casos de azoo- e oligospermia. Na região AFZc, o gene DAZ, que é suprimido na azoospermia, é considerado importante no controle espermatogênico, uma vez que a sua eliminação é frequentemente detectada em homens e/ou animais inférteis. -/- A perda total da capacidade de formação de espermatozoides pelo epitélio testicular e, portanto, a ausência de espermatozoides viáveis ou não no volume ejaculado pelo animal é denominado como azoospermia (VARNER et al., 2000), um macho nessas condições deve ser imediatamente retirado dos processos produtivos e não é, de forma alguma, viável para fins reprodutivos. A origem da causa pode ter caráter nutricional, ou outras, sendo multifatoriais; em processos crônicos severos pode-se chegar à azoospermia reversível, que é diagnosticada e corrigida de forma oportuna. Entre os principais fatores de caráter nutricional temos: -/- 18.1 Nitratos (NO3-) e nitritos (NO2-) -/- Quando os ruminantes consomem uma alimentação com elevadas concentrações de nitratos (presente principalmente nas forrageiras) parte do nitrato não pode ser imediatamente convertido em nitrito e, por fim, em amoníaco (todas essas transformações acontecem no rúmen mediante a flora microbiana); isso faz com que nitrato e nitrito se acumulem no rúmen. A adição do nitrato no rúmen intensifica o problema. O envenenamento por nitrato ocorre quando o nível de nitrito presente no rúmen excede a capacidade do microbiota para convertê-lo em amoníaco. Quando isto acontece, o nitrato e o nitrito são absorvidos através da parede do rúmen e entram na circulação sanguínea. É o nitrito que causa a toxicidade. -/- Estudou-se o equilíbrio ácido-básico e sua relação com a reprodução e produção, postulando a hipótese de que esse equilíbrio afeta os mecanismos endócrinos e metabólicos, além dos reprodutivos. -/- 18.2 Relação energia:proteína -/- Quando a alimentação apresenta deficiências de energia aumenta-se a degradação das gorduras (provenientes do tecido adiposo), acompanhada pela redução da liberação de insulina (hipoinsulinemia) afetando-se a lipogênese, mobilizando-se mais gordura corporal do que se sintetiza. -/- Situações como a acidose ruminal (excesso de grão e deficiência em fibras) ou alcalose ruminal (excesso de ureia com baixa energia digerível) resultam em perturbações sobre a fertilidade; além disso, deficiências energéticas graves que levam à cetose causam estresse com a liberação de catecolaminas, ACTH e TSH que afetam a secreção de GnRH, afetando por fim, a espermiogênese. -/- -/- Uma diminuição de energia na alimentação gera hipoglicemia que, ao mesmo tempo, produz hipoinsulinemia incrementando assim a lipólise em tecidos, gerando como produtos as cetonas. -/- A hipoinsulinemia juntamente com a cetonemia e a geração de beta-endorfinas, por problemas na alimentação, reduzem notavelmente a síntese de GnRH. A GnRH reduz a liberação do LH e FSH. A diminuição da liberação do LH provoca azoospermia hipogonadotrópica com efeitos de estimulação hormonal anormais segundo a avaliação endócrina, bem como a obstrução testicular inexplicada. -/- Se houver um aumento significativo na liberação de FSH, a azoospermia hipogonadotrópica é refletida em diagnóstico como disfunção testicular. -/- 18.3 Minerais (Selênio Se) -/- Quando os níveis de Se na dieta são deficientes, ocorrem falhas na formação e maturação espermática. O Se mostra uma grande influência na fertilidade do macho afetando a qualidade do sêmen, o plasma seminal contém elevadas quantidades de GSH-Px, cuja função é proteger a membrana do espermatozoide do ataque peroxidativo; além disso, na cauda do gameta masculino há um selenopeptídeo que faz com que, em uma deficiência de Se, produza-se uma fratura no meio da cauda do espermatozoide. -/- O esperma dos animais com deficiência de Se apresentam pobre motilidade com características de desenvolvimento anormal na cauda do esperma. Demonstrou-se que a deficiência de Se, não somente precipita o problema em reprodutores, mas que o esperma deformado, foi menos efetivo na subsequente fertilização do ovócito ovulado (HAWKES et al., 2001), ou seja, animais que possuem deficiência desse mineral podem ter esperma inapropriado para a destinação de inseminação artificial ou mesmo a monta natural, uma vez que a taxa de concepção estará bastante baixa. -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- BARRENHO, Gonçalo José Pinheiro. Nutrição e fertilidade em bovinos de leite. 2016. Dissertação de Mestrado. Universidade de Évora. -/- BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. -/- BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. -/- CHENOWETH, Peter J.; LORTON, Steven (Ed.). Animal Andrology: Theories and Applications. Boston: Cabi, 2014. -/- -/- DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. -/- DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. -/- DIAS, Juliano Cesar et al. Alguns aspectos da interação nutrição-reprodução em bovinos: energia, proteína, minerais e vitaminas. PUBVET, v. 4, p. Art. 738-743, 2010. -/- FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. -/- FRENEAU, G. E.; GUIMARÃES, J. D. Curso Teórico-Prático de Andrologia Bovina. Goiânia: Laboratório de andrologia e Tecnologia de Sêmen da Escola de Veterinária da Universidade Federal de Goiás, 2000. -/- GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. -/- HAWKES, WAYNE CHRIS; TUREK, PAUL J. Effects of dietary selenium on sperm motility in healthy men. Journal of Andrology, v. 22, n. 5, p. 764-772, 2001. -/- MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. -/- SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. -/- THATCHER, W. W. et al. Strategies for improving fertility in the modern dairy cow. Theriogenology, v. 65, n. 1, p. 30-44, 2006. -/- TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. -/- VARNER, D. D. et al. Techniques for evaluating selected reproductive disorders of stallions. Animal reproduction science, v. 60, p. 493-509, 2000. (shrink)

Anche se questo volume è un po 'datato, ci sono pochi libri popolari recenti che si occupano specificamente della psicologia dell'omicidio ed è una rapida panoramica disponibile per pochi dollari, quindi ne vale comunque la pena. Non fa alcun tentativo di essere completo ed è un po ' superficiale in alcuni punti, con il lettore che si aspetta di riempire gli spazi vuoti dai suoi molti altri libri e la vasta letteratura sulla violenza. Per un aggiornamento vedere ad esempio, Buss, (...) Il Manuale di Psicologia Evolutiva 2nd ed. V1 (2016) p 265, 266, 270–282, 388–389, 545–546, 547, 566 e Buss, Psicologia Evolutiva 5th ed. (2015) p. 26, 96-97.223, 293-4, 300, 309-312, 410 e Shackelford e Hansen, L'evoluzione della violenza (2014).. È stato tra i migliori psicologi evoluzionisti per diversi decenni e copre una vasta gamma di comportamenti nelle sue opere, ma qui si concentra quasi interamente sui meccanismi psicologici che causano l'omicidio delle singole persone e la loro possibile funzione evolutiva nel SEE (Ambiente dell'adattamento evolutivo, cioè le pianure dell'Africa durante gli ultimi milioni di anni o giù di lì). Gli Buss iniziano notando che, come per altri comportamenti, spiegazioni "alternative" come la psicopatologia, la gelosia, l'ambiente sociale, le pressioni di gruppo, le droghe e l'alcol ecc. non spiegano realmente, poiché rimane la questione del motivo per cui questi producono impulsi omicidi, cioè sono le cause prossipate e non quelle evolutive finali (genetiche). Come sempre, inevitabilmente si riduce alla forma fisica inclusiva (selezione dei parenti), e così alla lotta per l'accesso agli accoppiamenti e alle risorse, che è la spiegazione finale per tutti i comportamenti in tutti gli organismi. I dati sociologici (e il buon senso) chiariscono che i maschi più giovani sono i più propensi ad uccidere. Presenta i suoi e altri dati omicidi provenienti da nazioni industrializzate, e culture tribali, uccisioni aspecifiche conspecifiche in animali, archeologia, dati dell'FBI e la propria ricerca sulle fantasie omicidi delle persone normali. Molte prove archeologiche continuano ad accumularsi di omicidi, tra cui quello di interi gruppi, o di gruppi meno giovani femmine, in epoca preistorica. Dopo aver esaminato i commenti di Buss, presento una brevissima sintesi della psicologia intenzionale (la struttura logica della razionalità), che è ampiamente trattata nei miei molti altri articoli e libri. Coloro che hanno un sacco di tempo che vogliono una storia dettagliata della violenza omicida da una prospettiva evolutiva possono consultare 'The Better Angels of Our Nature Why Violence Has Declined' di Steven Pinker e la mia recensione, facilmente disponibile in rete e in due dei miei ultimi libri. In breve, Pinker osserva che l'omicidio è diminuito costantemente e drammaticamente di un fattore di circa 30 dai nostri giorni come raccoglitori. Quindi, anche se le armi ora rendono estremamente facile per chiunque uccidere, la omicidio è molto meno comune. Pinker pensa che ciò sia dovuto a vari meccanismi sociali che mettono in evidenza i nostri "angeli migliori", ma penso che sia dovuto principalmente all'abbondanza temporanea di risorse dallo stupro spietato del nostro pianeta, insieme a una maggiore presenza della polizia, con la comunicazione e la sorveglianza e i sistemi legali che rendono molto più probabile essere puniti. Questo diventa chiaro ogni volta che c'è anche una breve e locale assenza della polizia. Coloro che desiderano un quadro aggiornato completo per il comportamento umano dalla moderna vista a due systems possono consultare il mio libro 'La struttura logica dellafilosofia, psicologia, Mind e il linguaggio in Ludwig Wittgenstein e John Searle' 2nd ed (2019). Coloro che sono interessati a più dei miei scritti possono vedere 'Talking Monkeys--Filosofia, Psicologia, Scienza, Religione e Politica su un Pianeta Condannato--Articoli e Recensioni 2006-2019 3rd ed (2019) e Suicidal Utopian Delusions in the 21st Century 5th ed (2019). (shrink)

This article explores the meeting of two approaches towards philosophy and education: the philosophy for children approach advocated by Lipman and others, and Schmid’s philosophical concept of Lebenskunst. Schmid explores the concept of the beautiful or good life by asking what is necessary for each individual to be able to develop their own art of living and which aspects of life are significant when shaping a good and beautiful life. One element of Schmid’s theory is the practical application of philosophy (...) through the notions of Bildung, reflection, prudence and practical wisdom, as well as the requirement for each individual to take responsibility for actively shaping their life as an artwork. In this sense, each person is the artist responsible for living their own beautiful life. We argue that there are useful parallels between Schmid’s concept of the art of living and P4C, such as the ideal of a holistic philosophy that is “lived.” The pragmatic approach of P4C focuses on the embodied learner who practices critical, caring and creative thinking. Both P4C and Schmid’s theory are reminiscent of the Aristotelian notion of practical wisdom, which allows for an approach to an education for life that prepares students to develop their own art of living. (shrink)

My goal in this paper is to show that naturalists cannot reasonably endorse moral realism. My argument will come in two parts. The first part aims to show that any plausible and naturalistically acceptable argument in favor of belief in objective moral properties will appeal in part to simplicity considerations (broadly construed)—and this regardless of whether moral properties are reducible to non-moral properties. The second part argues for the conclusion that appeals to simplicity justify belief in moral properties only if (...) either those properties are not objective or something like theism is true. Thus, if my argument is sound, naturalists can reasonably accept moral realism only if they are prepared to accept something like theism. But, as will become clear, naturalists can reasonably accept theism or something like it only if belief in some such doctrine is justified by the methods of science. For present purposes, I’ll assume (what I think virtually every naturalist will grant) that belief in theism and relevantly similar doctrines is not justified by the methods of science. Thus, I will conclude that naturalists cannot reasonably accept moral realism. (shrink)

In the present article, he explains why divine silence poses a serious intellectual obstacle to belief in God, and then goes on to consider ways of overcoming that obstacle. After considering several ways in which divine silence might actually be beneficial to human beings, he argues that perhaps silence is nothing more or less than God’s preferred mode of interaction with creatures like us. Perhaps God simply desires communion rather than overt communication with human beings, and perhaps God has provided (...) ways for us to experience God’s presence richly even amidst the silence. (shrink)

This article examines a fundamental question of justice in global health. Is it ethically preferable to provide a larger number of people with cheaper treatments that are less effective (or more toxic), or to restrict treatments to a smaller group to provide a more expensive but more effective or less toxic alternative? We argue that choosing to provide less effective or more toxic interventions to a larger number of people is favored by the principles of utility, equality, and priority for (...) those worst-off. Advocates are mistaken to demand that medical care provided in low-income and middle-income countries should be the same as in high-income countries. (shrink)

Recourse to a variety of well-constructed arguments is undoubtedly a significant strategic asset for cultivating more ethical eating habits and convincing others to follow suit. Nevertheless, common obstacles often prevent even the best arguments from getting traction in our lives. For one thing, many of us enter the discussion hampered by firmly-entrenched but largely uninvestigated assumptions about food that make it difficult to imagine how even well-supported arguments that challenge our familiar frames of culinary reference could actually apply to us. (...) When an argument contests our cherished food ways, we are inclined almost reflexively to dodge, downplay, or dismiss it, and all the more anxiously if we suspect it’s a good one. Moreover, even when we find such arguments convincing and resolve to change, we often discover to our chagrin that, when the buffet is open, we lack the will to act on our convictions. Whether the obstacle is a lack of imagination or a failure of will, the way to concrete moral progress is blocked. Our aim here is to consider how other modes of philosophical inquiry can help us to overcome these two obstacles that arise at the margins of philosophy’s argumentative contributions to food ethics. In part I, we diagnose these obstacles as common moral malaises—we call them the malaise of imagination and the malaise of will—that create existential unease for moral agents that can curtail their ability to eat in accordance with what they learn from philosophical arguments. We then propose that other modes of philosophical inquiry can serve as therapy for these malaises. In part II, we argue that philosophical hermeneutics (exemplified by Hans-Georg Gadamer) can treat the malaise of imagination by helping us to excavate and revise hidden prejudices that interfere with our ability authentically to engage arguments that challenge entrenched assumptions about food. In part III, we argue that philosophy as care of the self (exemplified by Pierre Hadot) can treat the malaise of will by helping us to identify habits of thought and action that hamper concrete progress toward new dietary ideals and to replace them, through repetitive exercises, with transformed habits. In a brief conclusion, we identify some benefits of this approach. (shrink)

The question raised by this volume is “How successful is naturalism?” The question presupposes that we already know what naturalism is and what counts as success. But, as anyone familiar with the literature on naturalism knows, both suppositions are suspect. To answer the question, then, we must first say what we mean in this context by both ‘naturalism’ and ‘success’. I’ll start with ‘success’. I will then argue that, by the standard of measurement that I shall identify here, naturalism is (...) an utter failure. (shrink)

It is common lore that standard, Kripke-style semantics for quantified modal logic is incompatible with the view that no individual may belong to more than one possible world, a view that seems to require a counterpart-theoretic semantics instead. Strictly speaking, however, this thought is wrong-headed. This note explains why.

The paper will have three sections. In section one I briefly present and respond to Byrne’s argument against theological realism. In section two, I present van Fraassen’s argument against analytic metaphysics and I show how, if sound, it constitutes a reason to reject both metaphysical and theological realism. In section three, I show how van Fraassen can be answered. Obviously what I am doing here falls far short of a full-blown defense of realism in either metaphysics or theology. But the (...) objections raised by van Fraassen and Byrne are tokens of a type of objection that I think is rather widely endorsed among those who are suspicious of these two brands of realism. Thus, responding to those objections constitutes an important first step in the direction of a defense. (shrink)

Three separate churches erected in Constantinople were all dedicated to the wisdom of Christ and erected on the same site one after the other. These churches were built between 360 and 537 AD by three different emperors: Constantius II, Theodosius the Younger, and Justinian I. The first two churches were consumed in flames after relatively short lives, but the final and greatest church still stands today, despite a history of extensive damage. This final edifice is the main focus of this (...) paper, owing to its 1500 year longevity and unprecedented architecture. If the entire History of Justinian's church is to considered, it is inaccurate to refer to it as a “church,” because although it remained a church for the first 900 years after its audacious construction, it was later converted into a mosque. Today it is a museum, in remembrance of its long history. (24). (shrink)

This article argues that a person’s well-being at a time and the goodness of her life are two distinct values. It is commonly accepted as platitudinous that well-being is what makes a life good for the person who lives it. Even philosophers who distinguish between well-being at a time and the goodness of a life still typically assume that increasing a person’s well-being at some particular moment, all else equal, necessarily improves her life on the whole. I develop a precise (...) statement of this standard assumption, and then show that it is subject to counterexamples. The possibility of such counterexamples depends only on premises similar to those sometimes invoked to argue that a person’s well-being over a long period is not simply the aggregate well-being of the shorter periods that compose the long period. The refutation of the standard assumption linking well-being and life-goodness entails that these are distinct and sometimes divergent values. As an alternative to the standard assumption, it is proposed that well-being is best understood as an ingredient in a good life. (shrink)

Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...) plus conduct or oppositional defiant disorder. Design — Case-control study. Setting — Government clinical research institute. Participants — Forty-two adolescents aged 10 to 17 years: 14 with psychopathic traits and oppositional defiant disorder or conduct disorder, 14 with attention-deficit/hyperactivity disorder only, and 14 healthy controls. Main Outcome Measure — Blood oxygenation level–dependent signal as measured via functional magnetic resonance imaging during a probabilistic reversal task. Results — Children with psychopathic traits showed abnormal responses within the ventromedial prefrontal cortex (Brodmann area 10) during punished reversal errors compared with children wit hattention deficit/hyperactivity disorder and healthy children (P < .05 corrected for multiple comparisons). Conclusions — To our knowledge, this study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder. These findings suggest that reversal learning impairments in patients with developmental psychopathic traits relate to abnormal processing of reinforcement information. (shrink)

This paper seeks to indicate some connections between a major philosophi- cal project of the seventeenth century, the conception of a mathesis universalis, and the practice of baroque poetry. I shall argue that these connections consist in a peculiar view of language and systems of notation which was particularly common in European baroque culture and which provided the necessary conceptual background for both poetry and the mathesis universalis.

This is the Guest Editor's Introduction to a volume of Philosophia Reformata that considers Jaap Klapwijk's book in which he seeks to discuss evolutionary biology in relation to Christian philosophy.

This is a review of Henk Woldring's book on Karl Mannheim.

We try to show that there is no difference in principle between communicating a piece of information to a human and to a machine. The argumentation depends on the following theses: Communicating is transfer of information; information has propositional form; propositional form can be modelled as categorization; categorisation can be modelled in a machine; a suitably equipped machine can grasp propositional content designed for human communication. What I suggest is that the discussion should focus on the truth and precise meaning (...) of these statements. However, in case these statements are true it follows that: For any act of communication that successfully transfers a piece of information to a human, that act could also transfer that piece of information to a machine. (shrink)

Collingwood’s aim in The Principles of Art is “to answer the question: What is art?” (p. 1) The answer Collingwood offers to that question, that art is the expression of emotion, has become notorious for its implausibility. I consider one objection against this theory, namely that it is unclear what is rendered art by this definition: for it sometimes appears to define art too broadly, containing all utterances and gestures; but at other times to define art too narrowly, excluding much (...) of what we intuitively consider art. -/- I argue that this objection is mistaken, because it is founded upon a misunderstanding of the sort of project in which Collingwood is engaged. I propose a new reading, via his philosophical methodology, under which ‘art’ is differentially rather than binarily realisable. According to this new reading, art is something found in every human experience or activity, but to a greater or lesser extent. I close by suggesting one reason why Collingwood’s project under this reading is more philosophically interesting than it is under the standard reading, namely that it can give a better account of borderline cases of art. (shrink)

I defend a new argument for causal finitism, the view that nothing can have an infinite causal history. I begin by defending a number of plausible metaphysical principles, after which I explore a host of novel variants of the Littlewood-Ross and Thomson’s Lamp paradoxes that violate such principles. I argue that causal finitism is the best solution to the paradoxes.

Modal collapse arguments are all the rage in certain philosophical circles as of late. The arguments purport to show that classical theism entails the absurdly fatalistic conclusion that everything exists necessarily. My first aim in this paper is bold: to put an end to action-based modal collapse arguments against classical theism. To accomplish this, I first articulate the ‘Simple Modal Collapse Argument’ and then characterize and defend Tomaszewski’s criticism thereof. Second, I critically examine Mullins’ new modal collapse argument formulated in (...) response to the aforementioned criticism. I argue that Mullins’ new argument does not succeed. Third, I critically examine a powers-based modal collapse argument against classical theism that has received much less attention in the literature. Fourth, I show why God’s being purely actual, as well God’s being identical to each of God’s acts, simply cannot entail modal collapse given indeterministic causation. This, I take it, signals the death of modal collapse arguments. But not all hope is lost for proponents of modal collapse arguments—for the death is a fruitful one insofar as it paves the way for new inquiry into at least two new potential problems for classical theism. Showing this is my paper’s second aim. (shrink)

Functional decomposition is an important goal in the life sciences, and is central to mechanistic explanation and explanatory reduction. A growing literature in philosophy of science, however, has challenged decomposition-based notions of explanation. ‘Holists’ posit that complex systems exhibit context-sensitivity, dynamic interaction, and network dependence, and that these properties undermine decomposition. They then infer from the failure of decomposition to the failure of mechanistic explanation and reduction. I argue that complexity, so construed, is only incompatible with one notion of decomposition, (...) which I call ‘atomism’, and not with decomposition writ large. Atomism posits that function ascriptions must be made to parts with minimal reference to the surrounding system. Complexity does indeed falsify atomism, but I contend that there is a weaker, ‘contextualist’ notion of decomposition that is fully compatible with the properties that holists cite. Contextualism suggests that the function of parts can shift with external context, and that interactions with other parts might help determine their context-appropriate functions. This still admits of functional decomposition within a given context. I will give examples based on the notion of oscillatory multiplexing in systems neuroscience. If contextualism is feasible, then holist inferences are faulty—one cannot infer from the presence of complexity to the failure of decomposition, mechanism, and reductionism. (shrink)