Results for 'Substance use disorder'

965 found
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  1. (Mis)treating Substance Use Disorder With Prison.Kaitlin Puccio - 2019 - Voices in Bioethics 5.
    It is largely unethical to sentence individuals who are addicted to drugs to prison. While substance use can be a crime, it must be treated differently from other crimes because addiction is a psychiatric disorder. Prisons are penal institutions. Legitimate goals of penal sanctions include retribution, deterrence, rehabilitation, and incapacitation.[i] Most of these goals do not speak to those with substance use disorder, and incarceration may be counterproductive given the wide availability of drugs and feeble rehabilitation (...)
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  2. Psychosocial Disorders of Nigerian Society: Its Causes and Remedy.John Ezenwankwor - 2021 - Journal of Philosophy and Ethics 3 (2):1-8.
    This review aimed at exploring the psychosocial disorders of Nigeria as a nation, its effect on the citizens and the remedy. Psychosocial disorder is a mental illness induced by life experiences, stress, as well as maladaptive cognitive and behavioural processes. The prevalence of these disorders include depression, schizophrenia, anxiety disorders, substance use disorder, personality disorder and autism spectrum disorders have rapidly increase over the past years in Nigeria with its negative impact on the socioeconomic status, psychological (...)
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  3. Pornography Conceptualised as an Addictive Substance.Shirah Theron - 2023 - Dissertation, University of Stellenbosch
    Since the dawn of the internet, pornography has effectively become ubiquitous, pervasive, and increasingly normalised. Study findings show remarkable similarities in how the brain reacts to pornography, and other known addictive substances, and indicate that consuming pornography is comparable to consuming other known addictive substances. Moreover, two of the biggest risk factors for addiction are the substance’s availability and its easy accessibility, particularly in the case of younger persons. To date, pornography addiction has been conceptualised as a behavioural addiction. (...)
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  4. Anorexia: An Addiction. [REVIEW]Brianna Bright - manuscript
    Anorexia nervosa is an eating disorder characterized by very restrictive eating or dieting leading to weight loss, a fear of weight gain, and a distorted body image. Several physiological mechanisms and behaviors that maintain and worsen symptoms of anorexia have addictive qualities that parallel that of substance use disorder. Similarities between anorexia nervosa and substance use disorder are explored, including other relevant diagnoses and phenomenons like reward deficiency syndrome. Related mechanisms and behaviors associated with anorexia (...)
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  5. A Philosophical Psychotherapy: Logic-Based Therapy in the Treatment of Addicted Populations.Guy Pierre Du Plessis - 2022 - Presentation at the 4th International Conference on Philosophical Counseling and Practice, National Philosophical Counseling Association, 11-12 February 2022.
    In my presentation I argue for the utility of a philosophical counseling method, called logic-based therapy (LBT), in the treatment of addicted populations. In the context of addiction treatment LBT could be also classified as a philosophical psychotherapy. Philosophical psychotherapy can be understood as an umbrella term for interventions designed to treat mental health disorders, with theoretical foundations that are philosophical. Philosophical psychotherapy would be distinct from philosophical counseling, as the latter does not directly treat mental health disorders. I suggest (...)
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  6. Externalizing psychopatholog yand the error-related negativity.J. R. Hall, E. M. Bernat & C. J. Patrick - 2007 - Psychological Science 18 (4):326-333.
    Prior research has demonstrated that antisocial behavior, substance-use disorders, and personality dimensions of aggression and impulsivity are indicators of a highly heritable underlying dimension of risk, labeled externalizing. Other work has shown that individual trait constructs within this psychopathology spectrum are associated with reduced self-monitoring, as reflected by amplitude of the error-related negativity (ERN) brain response. In this study of undergraduate subjects, reduced ERN amplitude was associated with higher scores on a self-report measure of the broad externalizing construct that (...)
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  7. An Integral Guide to Recovery: Twelve Steps and Beyond.Guy Du Plessis - 2015 - Tucson, AZ, USA: Integral Publishers.
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  8. An Integral Foundation for Addiction Treatment: Beyond the Biopsychosocial Model.Guy Du Plessis - 2017 - AZ, Tuscan: Integral Publishers.
    Currently there is such a cornucopia of conflicting theories in the field of addiction studies that it has become exceedingly difficult for treatment providers, therapists, and policymakers to integrate this vast field of knowledge into effective treatment. Since such a chaotic overabundance of treatment theories, styles, and definitions cloud the field of addictionology, many therapists claim their field is in need of a paradigm shift. In the last 20 years an integrative and compound model has emerged known as the biopsychosocial (...)
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  9. Philosophy as a Way of Life for Addiction Recovery: A Logic-Based Therapy Case Study.Guy du Plessis - 2021 - International Journal of Applied Philosophy 35 (2):159-170.
    In this essay I explore the notion of philosophy as a way of life as a recovery pathway for individuals in addiction recovery. My hypothesis is that philosophy as a way of life can be a compelling, and legitimate recovery pathway for individuals in addiction recovery, as one of many recovery pathways. I will focus on logic-based therapy applied in the context of addiction recovery. The aim of presenting a case study is to show how a client receiving LBT is (...)
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  10. The Integrated Recovery Model for Addiction Treatment and Recovery.Guy Du Plessis - 2010 - Journal of Integral Theory and Practice 5 (3):68-87.
    This article outlines an integrally informed model for addictionon treatment and recover that is being pioneered and developed at Tabankulu Secondary Addiction Recovery Center in Cape Town, South Africa. Tabankulu is the world’s first inpatient Addictionon treatment center to implement an integrally informed treatment model. The Integrated Recovery model is a comprehensive, balanced, multi-phased, and multi-disciplinary approach to the treatment of and recovery from addiction. Its philosophy is derived from integrang a 12 Step abstinence-based methodology, mindfulness-based interventions, positive psychology, and (...)
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  11. Toward an Integral Model of Addiction: By means of integral methodological pluralism as a metatheoretical and integrative conceptual framework.Guy Du Plessis - 2012 - Journal of Integral Theory and Practice 7 (3):1-24.
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  12. Integrated Recovery Therapy: Towards an Integrally Informed Psychotherapy for Addicted Populations.Guy Pierre Du Plessis - 2012 - Journal of Integral Theory and Practice 7 (1):124-148.
    Abstract This article proposes and outlines an integrally informed 12 Step-based therapy that is adapted for treating addicted populations. Integrated Recovery Therapy (IRT) as a therapeutic orientation is an Integral Methodological Pluralism to therapy for treating addiction. Its two main features are paradigmatic and meta-paradigmatic. The paradigmatic aspect refers to the recognition, compilation and implementation of various methodologies in a comprehensive and inclusive manner. The meta-paradigmatic aspect refers to IRT’s capacity to weave together, relate and integrate the various paradigmatic practices. (...)
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  13. Computational Modelling for Alcohol Use Disorder.Matteo Colombo - forthcoming - Erkenntnis:1-21.
    In this paper, I examine Reinforcement Learning modelling practice in psychiatry, in the context of alcohol use disorders. I argue that the epistemic roles RL currently plays in the development of psychiatric classification and search for explanations of clinically relevant phenomena are best appreciated in terms of Chang’s account of epistemic iteration, and by distinguishing mechanistic and aetiological modes of computational explanation.
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  14. Should Adolescents be Included in Emerging Psychedelic Research?Khaleel Rajwani - unknown
    Recent evidence shows significant potential for therapies involving psychedelic substances such as psilocybin and MDMA to improve clinical outcomes for patients experiencing various mental disorders. However, research to date focuses almost exclusively on adults. I argue that adolescents should be included in research into psychedelic therapies. First, I demonstrate the pressing need for novel interventions to address the growing mental health burden of adolescents, and I draw on empirical evidence to show that research into psychedelic therapies presents an opportunity to (...)
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  15. Biological Interventions for Crime Prevention.Christopher Chew, Thomas Douglas & Nadira Faber - 2018 - In David Birks & Thomas Douglas (eds.), Treatment for Crime: Philosophical Essays on Neurointerventions in Criminal Justice. Oxford: Oxford University Press.
    This chapter sets the scene for the subsequent philosophical discussions by surveying a number of biological interventions that have been used, or might in the future be used, for the purposes of crime prevention. These interventions are pharmaceutical interventions intended to suppress libido, treat substance abuse or attention deficit-hyperactivity disorder (ADHD), or modulate serotonin activity; nutritional interventions; and electrical and magnetic brain stimulation. Where applicable, we briefly comment on the historical use of these interventions, and in each case (...)
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  16. Indigenous ayahuasca ceremonies in the European context: structures, purposes, concepts.Mika Turkia - manuscript
    Psychedelics are currently being studied intensively for the treatment of various psychiatric disorders. Ayahuasca, a plant-based extract originating from the Amazonian area, is traditionally consumed in ritualistic group events. The related indigenous traditions date back hundreds of years and have amassed vast amounts of knowledge on the therapeutic use of psychedelic and non-psychedelic plant-based substances. -/- These traditions require a prospective ceremony facilitator to undergo years of intensive training to acquire knowledge, mental power or self-confidence, stability, sensitivity, intuitive treatment outcome (...)
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  17. Phytochemistry and Phytochemical Potential of Curcuma longa: A Narrative Review.Akram Muhammad - 2024 - Journal of Science Technology and Research 5 (1):44-56.
    Since the beginning of recorded history, Curcuma longa has been valued for its medicinal benefits as a root crop. Turmeric's phytochemicals, which include curcuminoids, essential oils, and other bioactive substances, are principally responsible for its therapeutic effects. The Phytochemistry of Curcuma longa is described in this narrative review, with special attention paid to the major classes of phytochemicals and their potential for medicinal use. The therapeutic properties of the curcuminoids, particularly curcumin, as well as their potential to prevent and cure (...)
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  18. The Shadow of God in the Garden of the Philosopher. The Parc de La Villette in Paris in the context of philosophy of chôra. Part III.Cezary Wąs - 2019 - Quart. Kwartalnik Instytutu Historii Sztuki Uniwersytetu Wrocławskiego 2 (52):89-119.
    Tschumi believes that the quality of architecture depends on the theoretical factor it contains. Such a view led to the creation of architecture that would achieve visibility and comprehensibility only after its interpretation. On his way to creating such an architecture he took on a purely philosophical reflection on the basic building block of architecture, which is space. In 1975, he wrote an essay entitled Questions of Space, in which he included several dozen questions about the nature of space. The (...)
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  19. Cień Boga w ogrodzie filozofa. Parc de La Villette w Paryżu w kontekście filozofii chôry.Wąs Cezary - 2021 - Wrocław: Wydawnictwo Uniwersytetu Wrocławskiego.
    The Shadow of God in the Philosopher’s Garden. The Parc de La Villette in Paris in the context of the philosophy of chôra I Bernard Tschumi’s project of the Parc de La Villette could have won the competition and was implemented thanks to the political atmosphere that accompanied the victory of the left-wing candidate in the French presidential elections in 1981. François Mitterand’s revision of the political programme and the replacement of radical reforms with the construction of prestigious architectural objects (...)
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  20. The usefulness of substances. Knowledge, science and metaphysics in Nietzsche and Mach.Pietro Gori - 2009 - Nietzsche Studien 38 (1):111-155.
    In this paper I discuss the role played by Ernst Mach on Nietzsche’s thought. Starting from the contents of his Beiträge zur Analyse der Empfindungen, I’ll show the close similarities between their view on both human knowledge and the scientific world description. In his writing on science Nietzsche shares Mach’s critique to the 19th century mechanism and its metaphysical ground, as much as his way of defining the substantial notions such as matter, ego and free will. Moreover, my investigation will (...)
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  21. Embodied Imagination and Metaphor Use in Autism Spectrum Disorder.Zuzanna Rucinska, Shaun Gallagher & Thomas Fondelli - 2021 - Healthcare 9 (9):200.
    This paper discusses different frameworks for understanding imagination and metaphor in the context of research on the imaginative skills of children with autism spectrum disorder (ASD). In contrast to a standard linguistic framework, it advances an embodied and enactive account of imagination and metaphor. The paper describes a case study from a systemic therapeutic session with a child with ASD that makes use of metaphors. It concludes by outlining some theoretical insights into the imaginative skills of children with ASD (...)
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  22. The potential use of artificial intelligence in the therapy of borderline personality disorder.Judit Szalai - 2021 - Journal of Evaluation in Clinical Practice 27 (3):491-496.
    This paper explores the possibility of AI-based addendum therapy for borderline personality disorder, its potential advantages and limitations. Identity disturbance in this condition is strongly connected to self-narratives, which manifest excessive incoherence, causal gaps, dysfunctional beliefs, and diminished self-attributions of agency. Different types of therapy aim at boosting self-knowledge through self-narratives in BPD. The suggestion of this paper is that human-to-human therapy could be complemented by AI assistance holding out the promise of making patients' self-narratives more coherent through improving (...)
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  23. In Defense of Substance.Kathrin Koslicki - 2015 - Grazer Philosophische Studien 91 (1):59-80.
    In his “Farewell to Substance: A Differentiated Leave-Taking”, Peter Simons reaches the provocative conclusion that the concept of substance, as it is employed by metaphysicians, has become obsolete, since in the end there may be nothing at all which answers to it. No harm is done, Simons allows, if we continue to retain an everyday notion of substance, as long as we are aware of the limitations of this practice: there is no reason in general to expect (...)
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  24. Substance, Independence and Unity.Kathrin Koslicki - 2013 - In Edward Feser (ed.), Aristotle on Method and Metaphysics. New York: Palgrave-Macmillan. pp. 169-195.
    In this paper, I consider particular attempts by E. J. Lowe and Michael Gorman at providing an independence criterion of substancehood and argue that the stipulative exclusion of non-particulars and proper parts (or constituents) from such accounts raises difficult issues for their proponents. The results of the present discussion seem to indicate that, at least for the case of composite entities, a unity criterion of substancehood might have at least as much, and perhaps more, to offer than an independence criterion (...)
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  25. The Content of Kant's Pure Category of Substance and Its Use on Phenomena and Noumena.James Messina - 2021 - Philosophers' Imprint 21 (29).
    I begin by arguing that, for Kant, the pure category of substance has both a general content that is in play whenever we think of any entity as a substance as well as a more specific content that arises in conjunction with the thought of what Kant calls a positive noumenon. Drawing on this new “Dual Content” account of the pure category of substance, I offer new answers to two contested questions: What is the relation of the (...)
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  26. “Spinoza’s Metaphysics of Substance”.Y. Melamed Yitzhak - 2021 - In Garrett Don (ed.), Don Garrett (ed.), The Cambridge Companion to Spinoza. 2nd edition. Cambridge: Cambridge University Press, forthcoming. Cambridge UP. pp. 61-112.
    Substance’ (substantia, zelfstandigheid) is a key term of Spinoza’s philosophy. Like almost all of Spinoza’s philosophical vocabulary, Spinoza did not invent this term, which has a long history that can be traced back at least to Aristotle. Yet, Spinoza radicalized the traditional notion of substance and made a very powerful use of it by demonstrating – or at least attempting to demonstrate -- that there is only one, unique substance -- God (or Nature) -- and that all (...)
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  27. (2 other versions)Spinoza's Metaphysics: Substance and Thought.Yitzhak Y. Melamed - 2013 - Oxford: Oxford University Press USA.
    Yitzhak Melamed here offers a new and systematic interpretation of the core of Spinoza's metaphysics. In the first part of the book, he proposes a new reading of the metaphysics of substance in Spinoza: he argues that for Spinoza modes both inhere in and are predicated of God. Using extensive textual evidence, he shows that Spinoza considered modes to be God's propria. He goes on to clarify Spinoza's understanding of infinity, mereological relations, infinite modes, and the flow of finite (...)
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  28. (3 other versions)“Spinoza’s Metaphysics of Substance” in Don Garrett (ed.), The Cambridge Companion to Spinoza. 2nd edition. Cambridge: Cambridge University Press, forthcoming.Yitzhak Melamed - forthcoming - In Garrett Don (ed.), The Cambridge Companion to Spinoza. 2nd edition. Cambriddge University Press.
    Substance’ (substantia, zelfstandigheid) is a key term of Spinoza’s philosophy. Like almost all of Spinoza’s philosophical vocabulary, Spinoza did not invent this term, which has a long history that can be traced back at least to Aristotle. Yet, Spinoza radicalized the traditional notion of substance and made a very powerful use of it by demonstrating – or at least attempting to demonstrate -- that there is only one, unique substance -- God (or Nature) -- and that all (...)
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  29. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for clinical and research applications.Eric Schiffman, Richard Ohrbach, E. Truelove, Edmond Truelove, John Look, Gary Anderson, Werner Ceusters, Barry Smith & Others - 2014 - Journal of Oral and Facial Pain and Headache 28 (1):6-27.
    Aims: The Research Diagnostic Criteria for Temporomandi¬bular Disorders (RDC/TMD) Axis I diagnostic algorithms were demonstrated to be reliable but below target sensitivity and specificity. Empirical data supported Axis I algorithm revisions that were valid. Axis II instruments were shown to be both reliable and valid. An international consensus workshop was convened to obtain recommendations and finalization of new Axis I diagnostic algorithms and new Axis II instruments. Methods: A comprehensive search of published TMD diagnostic literature was followed by review and (...)
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  30. Composite Substance, Common Notions, and Kenelm Digby's Theory of Animal Generation.Andreas Blank - 2007 - Science in Context 20 (1):1.
    This paper argues for two claims. (1) In his biological views, Kenelm Digby tries to reconcile aspects of an Aristotelian theory of composite substance with early modern corpuscularianism. (2) From a methodological point of view, he uses the Stoic-Epicurean epistemology of common notions in order to show the adequacy of his conciliatory approach. The first claim is substantiated by an analysis of Digby’s views on the role of mixture and homogeneity in the process of animal generation. The second claim (...)
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  31. Detection and Mathematical Modeling of Anxiety Disorder Based on Socioeconomic Factors Using Machine Learning Techniques.Razan Ibrahim Alsuwailem & Surbhi Bhatia - 2022 - Human-Centric Computing and Information Sciences 12:52.
    The mental risk poses a high threat to the individuals, especially overseas demographic, including expatriates in comparison to the general Arab demographic. Since Arab countries are renowned for their multicultural environment with half of the population of students and faculties being international, this paper focuses on a comprehensive analysis of mental health problems such as depression, stress, anxiety, isolation, and other unfortunate conditions. The dataset is developed from a web-based survey. The detailed exploratory data analysis is conducted on the dataset (...)
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  32.  35
    Arterial spin labeling as a promising alternative to FDG-PET for clinical diagnosis of patients with disorders of consciousness.Timothy Joseph Lane - manuscript
    Objective: To evaluate the potential of arterial spin labeling (ASL) as an alternative to FDG-PET in the diagnosis of disorders of consciousness (DOC), we conducted a comparative study of the two modalities. Methods: A total of 36 DOC patients (11 female; mean age = 49.67 ± 14.54 years) and 17 healthy control (HC) participants (9 female; mean age = 31.9 ± 9.6 years) underwent both FDG-PET scans that measure metabolism via glucose uptake and ASL scans that measure cerebral blood flow (...)
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  33. Aphantasia and Psychological Disorder: Current Connections, Defining the Imagery Deficit and Future Directions.Dan Cavedon-Taylor - 2022 - Frontiers in Psychology 13 (822989).
    Aphantasia is a condition characterised by a deficit of mental imagery. Since several psychopathologies are partially maintained by mental imagery, it may be illuminating to consider the condition against the background of psychological disorder. After outlining current findings and hypotheses regarding aphantasia and psychopathology, this paper suggests that some support for defining aphantasia as a lack of voluntary imagery may be found here. The paper then outlines potentially fruitful directions for future research into aphantasia in general and its relation (...)
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  34. Three Errors in the Substance View's Defense.Rob Lovering - 2018 - Kriterion - Journal of Philosophy 32 (3):25-58.
    According to the theory of intrinsic value and moral standing known as the “substance view,” all human beings have intrinsic value, full moral standing and, with these, a right to life. The substance view has been defended by numerous contemporary philosophers who use the theory to argue that the standard human fetus has a right to life and, ultimately, that abortion is prima facie seriously wrong. In this paper, I identify three important errors committed by some of these (...)
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  35. Discussion protocol for alleviating epistemic injustice: The case of community rehabilitation interaction and female substance abusers.Petra Auvinen, Jaana Parviainen, Lauri Lahikainen & Hannele Palukka - 2021 - Social Sciences 10 (2).
    Substance-abusing women are vulnerable to specific kinds of epistemic injustice, including stigmatization and discrimination. This article examines the development of the epistemic agency of female substance abusers by asking: How does the use of a formal discussion protocol in community rehabilitation interaction alleviate epistemic injustice and strengthen the epistemic agency of substance abusers? The data were collected in a Finnish rehabilitation center by videotaping six group discussions between social workers, peer support workers, and rehabilitation clients with (...) abuse problems. Of these data, one recorded group discussion between four female participants—two rehabilitation clients, a peer support worker, and a social adviser—was used in this paper. Using conversational analysis, the findings indicate that, through the collaborative activities of sharing experiential knowledge about substance abuse and discussing the experiences of abuse in the rehabilitation interaction, substance abusers can develop novel ways to strengthen their epistemic agency by enhanced self-awareness. The discussion protocol is an epistemic tool that professionals and clients can learn to use in ethically and epistemologically successful ways in interaction. The use of a discussion protocol is an example of social professionals’ clinical knowledge of intensifying collaboration and sharing experiential knowledge in community rehabilitation and other substance abuse services. (shrink)
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  36. The Rubber Hand Illusion Reveals Proprioceptive and Sensorimotor Differences in Autism Spectrum Disorders.Bryan Paton, Jakob Hohwy & Peter Enticott - 2011 - Journal of Autism and Developmental Disorders.
    Autism spectrum disorder is characterised by differences in unimodal and multimodal sensory and proprioceptive processing, with complex biases towards local over global processing. Many of these elements are implicated in versions of the rubber hand illusion, which were therefore studied in high-functioning individuals with ASD and a typically developing control group. Both groups experienced the illusion. A number of differences were found, related to proprioception and sensorimotor processes. The ASD group showed reduced sensitivity to visuotactile-proprioceptive discrepancy but more accurate (...)
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  37. The harm of medical disorder as harm in the damage sense.David G. Limbaugh - 2019 - Theoretical Medicine and Bioethics 40 (1):1-19.
    Jerome Wakefield has argued that a disorder is a harmful dysfunction. This paper develops how Wakefield should construe harmful in his harmful dysfunction analysis. Recently, Neil Feit has argued that classic puzzles involved in analyzing harm render Wakefield’s HDA better off without harm as a necessary condition. Whether or not one conceives of harm as comparative or non-comparative, the concern is that the HDA forces people to classify as mere dysfunction what they know to be a disorder. For (...)
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  38. Substance in bureaucratic procedures for healthcare resource allocation: a reply to Smith.Gabriele Badano - 2019 - Journal of Medical Ethics 45 (1):75-76.
    William Smith’s recent article criticises the so-called orthodox approaches to the normative analysis of healthcare resource allocation, associated to the requirement that decision-makers should abide by strictly procedural principles of legitimacy defining a deliberative democratic process. Much of the appeal of Smith’s argument goes down to his awareness of real-world processes and, in particular, to the large gap he identifies between well-led democratic deliberation and the messiness of the process through which the intuitively legitimate Affordable Care Act (ACA) was created. (...)
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  39. The DSM-5 introduction of the Social (Pragmatic) Communication Disorder as a new mental disorder: a philosophical review.M. Cristina Amoretti, Elisabetta Lalumera & Davide Serpico - 2021 - History and Philosophy of the Life Sciences 43 (4):1-31.
    The latest edition of the Diagnostic and Statistical Manual of Mental Disorders included the Social Communication Disorder as a new mental disorder characterized by deficits in pragmatic abilities. Although the introduction of SPCD in the psychiatry nosography depended on a variety of reasons—including bridging a nosological gap in the macro-category of Communication Disorders—in the last few years researchers have identified major issues in such revision. For instance, the symptomatology of SPCD is notably close to that of Autism Spectrum (...)
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  40. Effects of Deep Brain Stimulation on the lived experience of Obsessive-Compulsive Disorder patients.Sanneke de Haan, Erik Rietveld, Martin Stokhof & Damiaan Denys - 2015 - PLoS ONE 10 (8):1-29.
    Deep Brain Stimulation (DBS) is a relatively new, experimental treatment for patients suffering from treatment-refractory Obsessive Compulsive Disorder (OCD). The effects of treatment are typically assessed with psychopathological scales that measure the amount of symptoms. However, clinical experience indicates that the effects of DBS are not limited to symptoms only: patients for instance report changes in perception, feeling stronger and more confident, and doing things unreflectively. Our aim is to get a better overview of the whole variety of changes (...)
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  41. Abnormal Functional Relationship of Sensorimotor Network With Neurotransmitter-Related Nuclei via Subcortical-Cortical Loops in Manic and Depressive Phases of Bipolar Disorder.Timothy J. Lane - 2020 - Schizophrenia Bulletin 46 (1):163–174.
    Objective Manic and depressive phases of bipolar disorder (BD) show opposite psychomotor symptoms. Neuronally, these may depend on altered relationships between sensorimotor network (SMN) and subcortical structures. The study aimed to investigate the functional relationships of SMN with substantia nigra (SN) and raphe nuclei (RN) via subcortical-cortical loops, and their alteration in bipolar mania and depression, as characterized by psychomotor excitation and inhibition. -/- Method In this resting-state functional magnetic resonance imaging (fMRI) study on healthy (n = 67) and (...)
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  42. The concept of mental disorder and the DSM-V.Massimiliano Aragona - 2009 - Dialogues in Philosophy, Mental and Neuro Sciences 2 (1):1-14.
    In view of the publication of the DSM-V researchers were asked to discuss the theoretical implications of the definition of mental disorders. The reasons for the use, in the DSM-III, of the term disorder instead of disease are considered. The analysis of these reasons clarifies the distinction between the general definition of disorder and its implicit, technical meaning which arises from concrete use in DSM disorders. The characteristics and limits of this technical meaning are discussed and contrasted to (...)
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  43. Substance Abuse.Landon Frim & Harrison Fluss - 2018 - Epoché: A Journal for the History of Philosophy 23 (1):191-217.
    This paper will set out in plain language the basic ontology of “Deleuze’s Spinoza”; it will then critically examine whether such a Spinoza has, or indeed could have, ever truly existed. In this, it will be shown that Deleuze’s reading of Spinoza involves the imposition of three interlocking, formal principles. These are (1) Necessitarianism, (2) Immanence, and (3) Univocity. The uncovering of Deleuze’s use of these three principles, how they relate to one another, and what they jointly imply in terms (...)
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  44. ‘Except God, no substance can be conceived’: Spinoza on other substances.Ruben Noorloos - 2021 - Analysis 81 (4):656-65.
    This paper argues that Spinoza held substances other than God to be inconceivable. It uses this claim to develop a novel response to the Problem of Other Substances, the problem of explaining why some of Spinoza’s proofs for God’s existence cannot be used to prove the existence of a non-divine substance instead.
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  45. Hume on Substance: A Critique of Locke.Donald L. M. Baxter - 2014 - In Paul Lodge & Tom Stoneham (eds.), Locke and Leibniz on Substance. New York: Routledge. pp. 45-62.
    The ancient theory of substance and accident is supposed to make sense of complex unities in a way that respects both their unity and their complexity. On Hume’s view such complex unities are only fictitiously unities. This result follows from his thoroughgoing critique of the theory of substance. I will characterize the theory Hume is critiquing as it is presented in Locke, presupposing what Bennett calls the “Leibnizian interpretation.” Locke uses the word ‘substance’ in two senses. Call (...)
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  46. Reasons for endorsing or rejecting ‘self-binding directives’ in bipolar disorder: a qualitative study of survey responses from UK service users.Tania Gergel, Preety Das, Lucy Stephenson, Gareth Owen, Larry Rifkin, John Dawson, Alex Ruck Keene & Guy Hindley - 2021 - The Lancet Psychiatry 8.
    Summary Background Self-binding directives instruct clinicians to overrule treatment refusal during future severe episodes of illness. These directives are promoted as having potential to increase autonomy for individuals with severe episodic mental illness. Although lived experience is central to their creation, service users’ views on self-binding directives have not been investigated substantially. This study aimed to explore whether reasons for endorsement, ambivalence, or rejection given by service users with bipolar disorder can address concerns regarding self-binding directives, decision-making capacity, and (...)
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  47. Enactivism, other minds, and mental disorders.Joel Krueger - 2019 - Synthese 198 (Suppl 1):365-389.
    Although enactive approaches to cognition vary in terms of their character and scope, all endorse several core claims. The first is that cognition is tied to action. The second is that cognition is composed of more than just in-the-head processes; cognitive activities are externalized via features of our embodiment and in our ecological dealings with the people and things around us. I appeal to these two enactive claims to consider a view called “direct social perception” : the idea that we (...)
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  48. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.Timothy J. Lane - 2021 - Psychiatry Research: Neuroimaging 308.
    The neurotransmitters GABA and glutamate have been suggested to play a role in Major Depressive Disorder (MDD) through an imbalance between cortical inhibition and excitation. This effect has been highlighted in higher brain areas, such as the prefrontal cortex, but has also been posited in basic sensory cortices. Based on this, magnetic resonance spectroscopy (MRS) was used to investigate potential changes to GABA+ and glutamate+glutamine (Glx) concentrations within the occipital cortex in MDD patients (n = 25) and healthy controls (...)
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  49. Should DBS for Psychiatric Disorders be Considered a Form of Psychosurgery? Ethical and Legal Considerations.Devan Stahl, Laura Cabrera & Tyler Gibb - 2018 - Science and Engineering Ethics 24 (4):1119-1142.
    Deep brain stimulation (DBS), a surgical procedure involving the implantation of electrodes in the brain, has rekindled the medical community’s interest in psychosurgery. Whereas many researchers argue DBS is substantially different from psychosurgery, we argue psychiatric DBS—though a much more precise and refined treatment than its predecessors—is nevertheless a form of psychosurgery, which raises both old and new ethical and legal concerns that have not been given proper attention. Learning from the ethical and regulatory failures of older forms of psychosurgery (...)
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  50. Critique and Refinement of the Wakefieldian Concept of Disorder: An Improvement of the Harmful Dysfunction Analysis.Emmanuel Smith - 2022 - Journal of Medicine and Philosophy 47 (4):530-539.
    One way in which bioethicists can benefit the medical community is by clarifying the concept of disorder. Since insurance companies refer to the DSM for whether a patient should receive assistance, one must consider the consequences of one’s concept of disorder for who should be provided with care. I offer a refinement of Jerome Wakefield’s hybrid concept of disorder, the harmful dysfunction analysis. I criticize both the factual component and the value component of Wakefield’s account and suggest (...)
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