Background Genomic research on neurodevelopmental disorders (NDDs), particularly involving minors, combines and amplifies existing research ethics issues for biomedical research. We performed a review of the literature on the ethical issues associated with genomic research involving children affected by NDDs as an aid to researchers to better anticipate and address ethical concerns. Results Qualitative thematic analysis of the included articles revealed themes in three main areas: research design and ethics review, inclusion of research participants, and communication of research results. Ethical (...) issues known to be associated with genomic research in general, such as privacy risks and informed consent/assent, seem especially pressing for NDD participants because of their potentially decreased cognitive abilities, increased vulnerability, and stigma associated with mental health problems. Additionally, there are informational risks: learning genetic information about NDD may have psychological and social impact, not only for the research participant but also for family members. However, there are potential benefits associated with research participation, too: by enrolling in research, the participants may access genetic testing and thus increase their chances of receiving a (genetic) diagnosis for their neurodevelopmental symptoms, prognostic or predictive information about disease progression or the risk of concurrent future disorders. Based on the results of our review, we developed an ethics checklist for genomic research involving children affected by NDDs. Conclusions In setting up and designing genomic research efforts in NDD, researchers should partner with communities of persons with NDDs. Particular attention should be paid to preventing disproportional burdens of research participation of children with NDDs and their siblings, parents and other family members. Researchers should carefully tailor the information and informed consent procedures to avoid therapeutic and diagnostic misconception in NDD research. To better anticipate and address ethical issues in specific NDD studies, we suggest researchers to use the ethics checklist for genomic research involving children affected by NDDs presented in this paper. (shrink)

Biobanks act as the custodians for the access to and responsible use of human biological samples and related data that have been generously donated by individuals to serve the public interest and scientific advances in the health research realm. Risk assessment has become a daily practice for biobanks and has been discussed from different perspectives. This paper aims to provide a literature review on risk assessment in order to put together a comprehensive typology of diverse risks biobanks could potentially face. (...) Methodologically set as a typology, the conceptual approach used in this paper is based on the interdisciplinary analysis of scientific literature, the relevant ethical and legal instruments and practices in biobanking to identify how risks are assessed, considered and mitigated. Through an interdisciplinary mapping exercise, we have produced a typology of potential risks in biobanking, taking into consideration the perspectives of different stakeholders, such as institutional actors and publics, including participants and representative organizations. With this approach, we have identified the following risk types: economic, infrastructural, institutional, research community risks and participant’s risks. The paper concludes by highlighting the necessity of an adaptive risk governance as an integral part of good governance in biobanking. In this regard, it contributes to sustainability in biobanking by assisting in the design of relevant risk management practices, where they are not already in place or require an update. The typology is intended to be useful from the early stages of establishing such a complex and multileveled biomedical infrastructure as well as to provide a catalogue of risks for improving the risk management practices already in place. (shrink)

This paper engages the question of the extended mind hypothesis, specifically in terms of memory and mnemonics. I use the case of an external object which is set to trigger a memory internally, but is not the memory, to explore the idea of extension versus distribution. I use the example of tzitzit, which is a garment worn by observant Jewish men, where is states in scripture that seeing the tassels attached to the garment are supposed to trigger a specific memory. (...) The point of the essay is that extension is merely a metaphysical commitment, and that this commitment leads to some ethical issues. (shrink)

Relational aspects, such as involvement of donor’s relatives or friends in the decision-making on participation in a research biobank, providing relatives’ health data to researchers, or sharing research findings with relatives should be considered when reflecting on ethical aspects of research biobanks. The aim of this paper is to explore what the role of donor’s relatives and friends is in the process of becoming and being a biobank donor and which ethical issues arise in this context. We performed qualitative analysis (...) of 40 qualitative semi-structured interviews with biobank donors and researchers. The results show that relatedness to relatives or other types of close relationships played a significant role in the donors’ motivation to be involved in a biobank, risk-benefit assessment, and decisions on sharing information on research and its results. Interviewees mentioned ethical issues in the context of sharing relatives’ health-related data for research purposes and returning research findings that may affect their relatives. We conclude that the question of what information on family members may be shared with a biobank by research participants without informed consent of those relatives, and when family members become research subjects, lacks a clear answer and detailed guidelines, especially in the context of the introduction of the European Union’s (EU) General Data Protection Regulation. Researchers in Latvia and EU face ethical questions and dilemmas about returning research results and incidental findings to donors’ relatives, and donors need more information on sharing research results with relatives in the informed consent process. (shrink)

At the core of medicine is the idea to help fellow human beings by improving or even restoring their health. Let us call this the auxiliary stance of medicine—the motivation of medical intervention by reference to a moral obligation to guide our peers in their attempt to live a healthy and productive life. In parallel, the auxiliary stance is also central to public health, with a focus on prevention and health promotion. Taken together, we can view medicine and public health (...) as the two main human auxiliary endeavors to protect individuals and populations from health risks and help them to heal when sick. (shrink)

The COVID-19 pandemic demonstrated the benefits of international data sharing. Data sharing enabled the health care policy makers to make decisions based on real-time data, it enabled the tracking of the virus, and importantly it enabled the development of vaccines that were crucial to mitigating the impact of the virus. This data sharing is not the norm as data sharing needs to navigate complex ethical and legal rules, and in particular, the fragmented application of the General Data Protection Regulation (GDPR). (...) The introduction of the draft regulation for a European Health Data Space (EHDS) in May 2022 seeks to address some of these legal issues. If passed, it will create an obligation to share electronic health data for certain secondary purposes. While there is a clear need to address the legal complexities involved with data sharing, it is critical that any proposed reforms are in line with ethical principles and the expectations of the data subjects. In this paper we offer a critique of the EHDS and offer some recommendations for this evolving regulatory space. (shrink)

Based on a critical interpretative review of existing qualitative research investigating accounts of ‘lived experience’ of surrogates and intended parents from a relational perspective, this article proposes a typology of surrogacy arrangements. The review is based on the analysis of 39 articles, which belong to a range of different disciplines (mostly sociology, social psychology, anthropology, ethnology, and gender studies). The number of interviews in each study range from as few as seven to over one hundred. Countries covered include Australia, Canada, (...) Greece, India, Iran, Israel, Italy, Mexico, Norway, Russia, Sweden, UK, Ukraine, and the USA. Most studies focus only on surrogacy practices in one country (although often with intended parents from other countries), and some include several countries (e.g. interviewees from several countries or fieldwork in different field-sites). The proposed typology goes beyond the division between altruistic versus commercial, and traditional versus gestational surrogacy, in order to inform further research and to contribute to bioethical and policy debates on surrogacy in a transnational context. Four types of relations are identifiable: open, restricted, structured, and enmeshed. The criteria which influence these relationships are: the frequency and character of contact pre- and post-birth; expectations of both parties; the type of exchange involved in surrogacy arrangements; and cultural, legal, and economic contexts. The theoretical contribution of the article is to further the development of a relational justice approach to surrogacy. (shrink)

The aim of this paper is to propose a new approach in the form of multimodality as a semiotic method that can be used by marketers and semioticians to induce online flow, a psychological state, on a brand website. First, we refer to multimodality as a semiotic analysis that can be used for a better optimization of semiotic resource sets in meaning-making, and we distinguish it from another similar concept: multimedia. Second, after a critical literature review, we address the (...) flow construct - a state of mind sometimes experienced by people who are deeply involved and immersed in some event, object or activity. Previous quantitative studies show a correlation between online flow experience and other variables such as design, content, sound and layout that are suggested to be its antecedents. In our study, these flow antecedents are viewed as sets of signs or modes that can be orchestrated in order to create different levels of perceived challenge for brand website users. We consider that multimodality can be used for a better optimization of these various meanings as expressed by modes that are "essentially different in nature" (Bateman, 2008, p.54). Also, we refer to the online marketing outcomes of the online flow experience, in order to outline its importance and its implications in the online environment. The main conclusion of our paper is that multimodality can be used by scholars and practitioners as a premise to induce online flow on a brand website, by optimizing the sets of signs or modes. Originality – our contribution consists of an interdisciplinary approach. We use concepts from semiotics, positive psychology, and online marketing for a better understanding of how marketers and semioticians can positively influence online customer behaviour. (shrink)

Throughout what is now the more than 50-year history of the computer many theories have been advanced regarding the contribution this machine would make to changes both in the structure of society and in ways of thinking. Like other theories regarding the future, these should also be taken with a pinch of salt. The history of the development of computer technology contains many predictions which have failed to come true and many applications that have not been foreseen. While we must (...) reserve judgment as to the question of the impact on the structure of society and human thought, there is no reason to wait for history when it comes to the question: what are the properties that could give the computer such far-reaching importance? The present book is intended as an answer to this question. The fact that this is a theoretical analysis is due to the nature of the subject. No other possibilities are available because such a description of the properties of the computer must be valid for any kind of application. An additional demand is that the description should be capable of providing an account of the properties which permit and limit these possible applications, just as it must make it possible to characterize a computer as distinct from a) other machines whether clocks, steam engines, thermostats, or mechanical and automatic calculating machines, b) other symbolic media whether printed, mechanical, or electronic and c) other symbolic languages whether ordinary languages, spoken or written or formal languages. This triple limitation, however, (with regard to other machines, symbolic media and symbolic languages) raises a theoretical question as it implies a meeting between concepts of mechanical-deterministic systems, which stem from mathematical physics, and concepts of symbolic systems which stem from the description of symbolic activities common to the humanities. The relationship between science and the humanities has traditionally been seen from a dualistic perspective, as a relationship between two clearly separate subject areas, each studied on its own set of premises and using its own methods. In the present case, however, this perspective cannot be maintained since there is both a common subject area and a new - and specific - kind of interaction between physical and symbolic processes. (shrink)

I propose in this text a rhythmic theory of signs drawn from the thought of Gilles Deleuze and Félix Guattari. I name this theory a semiorhythmology. I suggest that the theory of rhythm developed in A Thousand Plateaus (1980) can be understood, in part, as the culmination of the diverse set of inquiries into signs that both Deleuze and Guattari undertook, individually and together, beginning in the 1960s. I first outline Deleuze’s theory of signs as a theory (...) of encounter as developed in Proust and Signs (1964) and Difference and Repetition (1968), following which I sketch Guattari’s engagements with signs and semiotics throughout the 1960s and 1970s, particularly through his notion of “a-signifying semiotics” and the concept of the “diagram” he adapts from the semiotics of Charles Sanders Peirce. I close by showing how these heterogeneous theories of the sign are drawn together in A Thousand Plateaus through the Spinozist reading of the ethology of Jakob von Uexküll and the theorisation of rhythm in the form of the refrain. (shrink)

A general class of labeled sequent calculi is investigated, and necessary and sufficient conditions are given for when such a calculus is sound and complete for a finite -valued logic if the labels are interpreted as sets of truth values. Furthermore, it is shown that any finite -valued logic can be given an axiomatization by such a labeled calculus using arbitrary "systems of signs," i.e., of sets of truth values, as labels. The number of labels needed is (...) logarithmic in the number of truth values, and it is shown that this bound is tight. (shrink)

Legal philosophers distinguish between a static and a dynamic interpretation of law. The former assumes that the meaning of the words used in a legal text is set at the moment of its enactment and does not change with time. The latter allows the interpreters to update the meaning and apply a contemporary understanding to the text. The dispute between these competing theories has significant ramifications for social and political life. To take an example, depending on the approach, the term (...) “cruel punishment” used in the US Constitution will be given an 18th century meaning or a contemporary one. -/- The philosophy of language seems to provide greater support to the static approach to legal interpretation. Within this approach the lawmaker is perceived as a speaker and legal texts are interpreted as utterances. As a consequence, interpretation is a quest for the speaker/lawmaker’s intention or the public meaning that prevailed at the time of enactment. Neither the intention nor the public meaning are considered to have changed in time. -/- In this paper I argue that the philosophy of language provides the dynamic approach with an equally robust support as the static one. This support comes from an externalist perspective in semantics, rooted in philosophical pragmatism and supported by Ruth Millikan’s concept of meaning as proper function. Grounding the dynamic approach in a well-founded linguistic philosophy rises to the challenge presented by the originalists’ declaration that “it takes a theory to beat a theory”. (shrink)

In recent decades, philosophers of science have devoted considerable efforts to understand what models represent. One popular position is that models represent fictional situations. Another position states that, though models often involve fictional elements, they represent real objects or scenarios. Though these two positions may seem to be incompatible, I believe it is possible to reconcile them. Using a threefold distinction between different signs proposed by Peirce, I develop an argument based on a proposal recently made by Kralemann and (...) Lattman (in Synthese 190:3397–3420, 2013) that shows that the two aforementioned positions can be reconciled by distinguishing different ways in which a model representation can be used. In particular, on the basis of Peirce’s distinction between icons, indices and symbols, I argue that models can sometimes function as icons, sometimes as indexes and sometimes as symbols, depending on the context in which they are considered and the use that they are developed for because they all have iconic, indexical and symbolic features. In addition, I show that conceiving models as signs enables us to develop an account of scientific representation that meets the main desiderata that Shech (in Synthese 192:3463–3485, 2015) presents. (shrink)

Transformed RAVAL NOTATION solves Syllogism problems very quickly and accurately. This method solves any categorical syllogism problem with same ease and is as simple as ABC… In Transformed RAVAL NOTATION, each premise and conclusion is written in abbreviated form, and then conclusion is reached simply by connecting abbreviated premises.NOTATION: Statements (both premises and conclusions) are represented as follows: Statement Notation a) All S are P, SS-P b) Some S are P, S-P c) Some S are not P, S / PP (...) d) No S is P, SS / PP (- implies are and / implies are not) All is represented by double letters; Some is represented by single letter. No S is P implies No P is S so its notation contains double letters on both sides. -/- RULES: (1) Conclusions are reached by connecting Notations. Two notations can be linked only through common linking terms. When the common linking term multiplies (becomes double from single), divides (becomes single from double) or remains double then conclusion is arrived between terminal terms. (Aristotle’s rule: the middle term must be distributed at least once) -/- (2)If both statements linked are having – signs, resulting conclusion carries – sign (Aristotle’s rule: two affirmatives imply an affirmative) -/- (3) Whenever statements having – and / signs are linked, resulting conclusion carries / sign. (Aristotle’s rule: if one premise is negative, then the conclusion must be negative) -/- (4)Statement having / sign cannot be linked with another statement having / sign to derive any conclusion. (Aristotle’s rule: Two negative premises imply no valid conclusion) Syllogism conclusion by Tranformed Raval’s Notation is in accordance with Aristotle’s rules for the same. It is visually very transparent and conclusions can be deduced at a glance, moreover it solves syllogism problems with any number of statements and it is quickest of all available methods. By new Raval method for solving categorical syllogism, solving categorical syllogism is as simple as pronouncing ABC and it is just continuance of Aristotle work on categorical syllogism. It’s believed that Boole's system could handle multi-term propositions and arguments, whereas Aristotle could handle only two-termed subject-predicate propositions and arguments. For example, it’s claimed that Aristotle's system could not deduce: "No quadrangle that is a square is a rectangle that is a rhombus" from "No square that is a quadrangle is a rhombus that is a rectangle" or from "No rhombus that is a rectangle is a square that is a quadrangle". Above conclusion is reached at a glance with Raval's Notations (Symbolic Aristotle’s syllogism rules). Premise: "No (square that is a quadrangle) is a (rhombus that is a rectangle)" Raval's Representations: S – Q, S – Q / Rh – Re, Rh – Re Premise: "No (rhombus that is a rectangle) is a (square that is a quadrangle)". Raval's Representations: Rh – Re, Rh – Re / S – Q, S - Q Conclusion: "No (quadrangle that is a square) is a (rectangle that is a rhombus)" Raval’s Representations: Q – S, Q – S / Re – Rh, Re – Rh As “ Q – S” follows from “S – Q” and “Re – Rh” from “Rh – Re”. Given conclusion follows from the given premises. Author disregards existential fallacy, as subset of a null set has to be a null set. -/- . (shrink)

The quantization error in a fixed-size Self-Organizing Map (SOM) with unsupervised winner-take-all learning has previously been used successfully to detect, in minimal computation time, highly meaningful changes across images in medical time series and in time series of satellite images. Here, the functional properties of the quantization error in SOM are explored further to show that the metric is capable of reliably discriminating between the finest differences in local contrast intensities and contrast signs. While this capability of the QE (...) is akin to functional characteristics of a specific class of retinal ganglion cells (the so-called Y-cells) in the visual systems of the primate and the cat, the sensitivity of the QE surpasses the capacity limits of human visual detection. Here, the quantization error in the SOM is found to reliably signal changes in contrast or colour when contrast information is removed from or added to the image, but not when the amount and relative weight of contrast information is constant and only the local spatial position of contrast elements in the pattern changes. While the RGB Mean reflects coarser changes in colour or contrast well enough, the SOM-QE is shown to outperform the RGB Mean in the detection of single-pixel changes in images with up to five million pixels. This could have important implications in the context of unsupervised image learning and computational building block approaches to large sets of image data (big data). (shrink)

Conceptual models as representations of real-world systems are based on diverse techniques in various disciplines but lack a framework that provides multidisciplinary ontological understanding of real-world phenomena. Concurrently, systems’ complexity has intensified, leading to a rise in developing models using different formalisms and diverse representations even within a single domain. Conceptual models have become larger; languages tend to acquire more features, and it is not unusual to use different modeling languages for different components. This diversity has caused problems with consistency (...) between models and incompatibly with designed systems. Two main solutions have been adopted over the last few years: (1) A currently dominant technology-based solution tries “to harmonize or unify” models, e.g., unifies EER and UML. This solution would solidify modeling achievements, reaping benefits from huge investments over the last thirty years. (2) A less prevalent solution is to pursuit deeper roots that reveal unifying modeling principles and apparatuses. An example of the second method is a “category theory”-based approach that utilizes the strengths of the graph and set theory, along with other topological tools. This manuscript is a sequel in a research venture that belongs to the second approach and uses a model called thinging machines (TMs) founded on Stoic ontology and Lupascian logic. TM modeling contests the thesis that there is no universal approach that covers all aspects of an application, and the paper demonstrates that pursuing such universality is anything but a dead-end method. This paper continues in this direction, with emphasis on TM foundation (e.g., existence and subsistence of things) and exemplifies this pursuit by proposing an alternative representation of set theory. (shrink)

Why study notations, diagrams, or more broadly the variety of nonverbal “representations” or “signs” that are used in mathematical practice? This chapter maps out recent work on the topic by distinguishing three main philosophical motivations for doing so. First, some work (like that on diagrammatic reasoning) studies signs to recover norms of informal or historical mathematical practices that would get lost if the particular signs that these practices rely on were translated away; work in this vein has (...) the potential to broaden our view of the specific normativity of mathematics beyond logical proof. Second, some work focuses on signs to highlight the open-ended and “nonrigorous” aspects of mathematical practice, and the role of these aspects in the historical development of mathematics. The third motivation is based on the following observation: the reason differences in signs matter in mathematics is that humans are finite agents, with cognitive and computational limitations. Accordingly, studying signs can be a way to study how human computational constraints shape the mathematics that we do, and to tackle the topic of mathematical understanding. (shrink)

The IndetermSoft Set is as an extension of the Soft Set, because the data, or the function, or the sets involved in the definition of the soft set have indeterminacy - as in our everyday life, and we still need to deal with such situations. And similarly, IndetermHyperSoft Set as extension of the HyperSoft Set, when there is indeterminate data, or indeterminate functions, or indeterminate sets. Herein, ‘Indeterm’ stands for ‘Indeterminate’ (uncertain, conflicting, incomplete, not unique outcome). We now (...) introduce for the first time the TreeSoft Set as extension of the MultiSoft Set. Several applications are presented for each type of soft set. (shrink)

Descartes held that it is impossible to make true statements about what we perceive, but I go over alleged cases of illusory experience to show why such a skeptical conclusion (and recourse to God) is overblown. The overreaction, I contend, stems from an insufficient awareness of the habitual expectations brought to any given experience. These expectations manifest themselves in motor terms, as perception constantly prompts and updates an embodied posture of readiness for what might come next. Such habitual anticipations work (...) best when they efface themselves, so it is easy to blame perception when our expectations get frustrated. I illustrate this misdirected blame with the example of a stick partially in water: it is only because we expect the stick to be straight that its appearance as bent is deemed problematic. I thus conclude that, if we factor in the habitual interpretations operative in perception and switch to a processual view that allows practical engagement, we can deflate the worries that led Descartes to rule out perceptual truths. Distancing myself from the naïve “sign” of folk semiotics, my critique draws inspiration from the triadic semiotic model developed in some late medieval schools of Portugal. (shrink)

Priority setting in health care is ubiquitous and health authorities are increasingly recognising the need for priority setting guidelines to ensure efficient, fair, and equitable resource allocation. While cost-effectiveness concerns seem to dominate many policies, the tension between utilitarian and deontological concerns is salient to many, and various severity criteria appear to fill this gap. Severity, then, must be subjected to rigorous ethical and philosophical analysis. Here we first give a brief history of the path to today’s severity criteria in (...) Norway and Sweden. The Scandinavian perspective on severity might be conducive to the international discussion, given its long-standing use as a priority setting criterion, despite having reached rather different conclusions so far. We then argue that severity can be viewed as a multidimensional concept, drawing on accounts of need, urgency, fairness, duty to save lives, and human dignity. Such concerns will often be relative to local mores, and the weighting placed on the various dimensions cannot be expected to be fixed. Thirdly, we present what we think are the most pertinent questions to answer about severity in order to facilitate decision making in the coming years of increased scarcity, and to further the understanding of underlying assumptions and values that go into these decisions. We conclude that severity is poorly understood, and that the topic needs substantial further inquiry; thus we hope this article may set a challenging and important research agenda. (shrink)

The link between the high-order metaphysics and abstractions, on the one hand, and choice in the foundation of set theory, on the other hand, can distinguish unambiguously the “good” principles of abstraction from the “bad” ones and thus resolve the “bad company problem” as to set theory. Thus it implies correspondingly a more precise definition of the relation between the axiom of choice and “all company” of axioms in set theory concerning directly or indirectly abstraction: the principle of abstraction, axiom (...) of comprehension, axiom scheme of specification, axiom scheme of separation, subset axiom scheme, axiom scheme of replacement, axiom of unrestricted comprehension, axiom of extensionality, etc. (shrink)

Many approaches to quantum gravity -the theory that should account for quantum and gravitational phenomena under the same theoretical umbrella- seem to point at some form of spacetime emergence, i.e., the fact that spacetime is not a fundamental entity of our physical world. This tenet has sparked many philosophical discussions: from the so-called empirical incoherence problem to different accounts of emergence and mechanisms thereof. In this contribution, I focus on the partial order relation of causal set theory and argue that (...) causation can be characterized as an a-temporal constraint over the kinematic space defined by the theory. The relation constrains the growth of a new element/event with respect to the other elements/events of a given set. Therefrom, the flow of time emerges from the collection of the possible growths of the given set, where each possibility is characterized by a classical probability assigned by the dynamics of the theory. (shrink)

Recently theorists have demonstrated a growing interest in the ethical aspects of resource allocation in international non-governmental humanitarian, development and human rights organizations (INGOs). This article provides an analysis of Thomas Pogge's proposal for how international human rights organizations ought to choose which projects to fund. Pogge's allocation principle states that an INGO should govern its decision making about candidate projects by such rules and procedures as are expected to maximize its long-run cost-effectiveness, defined as the expected aggregate moral value (...) of the projects it undertakes divided by the expected aggregate cost of these projects? I critique Pogge's argument on two fronts: (1) I demonstrate that his view is problematic on his own terms, even if we accept the cost-effectiveness framework he employs. (2) I take issue with his overall approach because it generates results which can undermine the integrity of INGOs. Further, his approach mis-characterizes the nature of INGOs, and this mistake is at the root of his problematic view of INGO priority-setting. Ultimately, I argue for a conception of INGOs in which they are understood as ?organizations of principle?, in the sense that they are independent moral agents and so should be permitted a fairly wide sphere of autonomy within reasonable moral constraints. (shrink)

Answer Set Programming is a new paradigm based on logic programming. The main component of answer set programming is a system that finds the answer sets of logic programs. During the computation of an answer set, systems are faced with choice points where they have to select a literal and assign it a truth value. Generally, systems utilize some heuristics to choose new literals at the choice points. The heuristic used is one of the key factors for the performance (...) of the system. A new heuristic for answer set programming has been developed. This heuristic is inspired by hierarchical planning. The notion of criticality, which was introduced for generating abstraction hierarchies in hierarchical planning, is used in this heuristic. The resulting system (CSMODELS) uses this new heuristic in a static way. CSMODELS is based on the system SMODELS. The experimental results show that this new heuristic is promising for answer set programming. A comparison of search times with SMODELS demonstrate CSMODELS’ usefulness. (shrink)

The Joker both fascinates and repels us. From his origin in Detective Comics in 1940, he has committed obscene crimes, some of the worst the Batman universe has ever known, and, conversely, fans have made him the topic of erotic and pornographic “fan fiction.” Speculation about the Joker abounds, where some fans have even claimed that the Joker is “queer coded.” This work explores various popular claims about the Joker, and delves into the history of comic books, and of other (...) popular media from a semiotic viewpoint to understand “The Clown Prince of Crime” in the contexts in which he existed to understand his evolution in the past. From his roots as a “typical hoodlum,” The Joker even starred in his own eponymous comic book series and he was recently featured in a non-canonical movie. This work examines what it is about the Joker which fascinates us. (shrink)

This paper accomplishes two tasks. First, I examine in detail Edmund Husserl’s earliest philosophy of surrogates, as it is found in his 1890 “On the Logic of Signs ”. I analyze his psychological and logical investigations of surrogates, where the former is concerned with explaining how these signs function and the latter with how they do so reliably. His differentiation of surrogates on the basis of their genetic origins and degrees of necessity is discussed. Second, the historical importance (...) of this text is disclosed by showing how Semiotic serves as both the inspiration for, and the foil to, Husserl’s 1901 First Logical Investigation. Husserl not only adopts the idea that linguistic signs can function via association, but also maintains that such signs can motivate me to execute one of two experiences. The key difference between the texts is that Husserl abandons his theory of surrogates in 1901, instead holding that I can experience absent objects by means of empty intentions. The reasons why Husserl found it necessary to transform this tenet of his philosophy are discussed at length. (shrink)

What makes public history more than just another hill to fight over in culture war politics? In this paper I propose a novel way of understanding the political significance of how public history creates and shapes identities: a contractarian one. I argue that public history can be sensibly understood as representing groups as a society’s contracting parties. One particular value of the contractarian approach is that it helps to elucidate the phenomenon of “signing on,” where a marginalized or oppressed group (...) is offered membership in a society without the social order being meaningfully changed. (shrink)

This article is a preliminary draft for initiating and commencing a new pioneer dimension of expression. To deal with higher-dimensional data or information flowing in this modern era of information technology and artificial intelligence, some innovative super algebraic structures are essential to be formulated. In this paper, we have introduced such matrices that have multiple layers and clusters of layers to portray multi-dimensional data or massively dispersed information of the plithogenic universe made up of numerous subjects their attributes, and sub-attributes. (...) For grasping that field of parallel information, events, and realities flowing from the micro to the macro level of universes, we have constructed hypersoft and hyper-super-soft matrices in a Plithogenic Fuzzy environment. These Matrices classify the non-physical attributes by accumulating the physical subjects and further sort the physical subjects by accumulating their non-physical attributes. We presented themasPlithogenicAttributiveSubjectivelyWholeHyper-Super-Soft-Matrix(PASWHSS-Matrix)andPlithogenic Subjective Attributively Whole-Hyper-Super-Soft-Matrix (PSAWHSS-Matrix). Several types of views and level-layers of these matrices are described. In addition, some local aggregation operators for Plithogenic Fuzzy Hypersoft Set (PPFHS-Set) are developed. Finally, few applications of these matrices and operators are used as numerical examples of COVID-19 data structures. (shrink)

We explore Peirce’s pragmatic conception of sign action, as a distributed and emergent view of cognition and exemplify with the emergence of classical ballet. In our approach, semiosis is a temporally distributed process in which a regular tendency towards certain future outcomes emerges out of a history of sign actions. Semiosis self-organizes in time, in a process that continuously entails the production of more signs. Emergence is a ubiquitous condition in this process: the translation of signs into (...) class='Hi'>signs cannot be inferred from the properties of the components of a semiotic triad alone, but has to take into account a complex interaction between a micro-semiotic and macro-semiotic level of description. This interaction can be understood as an interplay of potentialities and tendencies, or upward constitutive determinative relations and downward selective determinative relations. According to this view, emergence is a central defining condition of processes of meaning. Ballet is a sign in action. The emergence of classical ballet is a self-regulatory process, in which a system of different kinds of cognitive artifacts (musical, bodily/motor, spatial/architectonic) and agents obtained a stable semiotic relation throughout many phases of development between the 16th and the 19th Century. One case is the development of the verticality of dance in classical ballet as a semiotic relation connecting proscenium arch stages, dancing bodies, and audiences. This development is micro-semiotically determined by the spatial constraints of the proscenium arch stage, and macro-semiotically determined by a historical construction of the dancing body as a sign within a network of semiotic chains, such as the intersemiotic regulation of body of the dancer by principles coming from painting. This is not only the emergence of actual meaning, but also the emergence of an open-ended field of potential and general meanings, an autonomous tendency of development. To say that ballet, as sign action, emerges, is to say that cognitive artifacts such as dancer’s bodies, stages and audience’s point of view, musical compositions, costumes, all sorts of supporting institutions, etc, constitute a niche for sign action, interacting according to tendencies of development that didn’t exist before. (shrink)

Throughout Peirce’s writing, we witness his developing vision of a machine that scientists will eventually be able to create. Nadin (2010) raised the question:Why do computer scientists continue to ignore Peirce’s sign theory? A review of the literature on Peirce’s theory and the semiotics machine reveals that many authors discussed the machine;however, they donot differentiate between a physical computer machine and its software. This paper discusses the problematic issues involved in converting Peirce’s theory into a programming language, machine and software (...) application. We demonstrate this challenge by introducing Peirce’s sign theory as a software application that runs under an open-source R environment. (shrink)

This paper shows how the classical finite probability theory (with equiprobable outcomes) can be reinterpreted and recast as the quantum probability calculus of a pedagogical or toy model of quantum mechanics over sets (QM/sets). There have been several previous attempts to develop a quantum-like model with the base field of ℂ replaced by ℤ₂. Since there are no inner products on vector spaces over finite fields, the problem is to define the Dirac brackets and the probability calculus. The (...) previous attempts all required the brackets to take values in ℤ₂. But the usual QM brackets <ψ|ϕ> give the "overlap" between states ψ and ϕ, so for subsets S,T⊆U, the natural definition is <S|T>=|S∩T| (taking values in the natural numbers). This allows QM/sets to be developed with a full probability calculus that turns out to be a non-commutative extension of classical Laplace-Boole finite probability theory. The pedagogical model is illustrated by giving simple treatments of the indeterminacy principle, the double-slit experiment, Bell's Theorem, and identical particles in QM/Sets. A more technical appendix explains the mathematics behind carrying some vector space structures between QM over ℂ and QM/Sets over ℤ₂. (shrink)

A theory of mind is provided by assuming thoughts are mathematical objects (more specifically, constructible using set-theory). Problems from the philosophy of mind are probed using mathematical analogy, and the relation of minds to bodies is clarified using relations that are typical between mathematical structures.

Instead of the half-century old foundational feud between set theory and category theory, this paper argues that they are theories about two different complementary types of universals. The set-theoretic antinomies forced naïve set theory to be reformulated using some iterative notion of a set so that a set would always have higher type or rank than its members. Then the universal u_{F}={x|F(x)} for a property F() could never be self-predicative in the sense of u_{F}∈u_{F}. But the mathematical theory of categories, (...) dating from the mid-twentieth century, includes a theory of always-self-predicative universals--which can be seen as forming the "other bookend" to the never-self-predicative universals of set theory. The self-predicative universals of category theory show that the problem in the antinomies was not self-predication per se, but negated self-predication. They also provide a model (in the Platonic Heaven of mathematics) for the self-predicative strand of Plato's Theory of Forms as well as for the idea of a "concrete universal" in Hegel and similar ideas of paradigmatic exemplars in ordinary thought. (shrink)

This paper accomplishes two goals. First, I elucidate Edmund Husserl’s theory of inauthentic judgments from his 1890 “On the Logic of Signs (Semiotic).” It will be shown how inauthentic judgments are distinct from other signitive experiences, in such a manner that when Husserl seeks to account for them, he is forced to revise the general structure of his philosophy of meaning and in doing so, is also able to realize novel insights concerning the nature of signification. Second, these conclusions (...) are revealed to be the foundation of Husserl’s pure logical grammar, found in the 1901 “Fourth Logical Investigation.” In his analysis of inauthentic judgments, Husserl already recognized, albeit in a problematic way and for entirely different reasons, many of the central tenets of the 1901 work concerning categoremata and syncategoremata, matter and form, and the isomorphism between them. (shrink)

As the English word “scientism” is currently used, it is a trivial verbal truth that scientism—an inappropriately deferential attitude to science—should be avoided. But it is a substantial question when, and why, deference to the sciences is inappropriate or exaggerated. This paper tries to answer that question by articulating “six signs of scientism”: the honorific use of “science” and its cognates; using scientific trappings purely decoratively; preoccupation with demarcation; preoccupation with “scientific method”; looking to the sciences for answers beyond (...) their scope; denying the legitimacy or worth of non-scientific (e.g., legal or literary) inquiry, or of writing poetry or making art. (shrink)

Consider a variant of the usual story about the iterative conception of sets. As usual, at every stage, you find all the (bland) sets of objects which you found earlier. But you also find the result of tapping any earlier-found object with any magic wand (from a given stock of magic wands). -/- By varying the number and behaviour of the wands, we can flesh out this idea in many different ways. This paper's main Theorem is that any (...) loosely constructive way of fleshing out this idea is synonymous with a ZF-like theory. -/- This Theorem has rich applications; it realizes John Conway's (1976) Mathematicians' Liberation Movement; and it connects with a lovely idea due to Alonzo Church (1974). (shrink)

In this paper we define the Soft Set Product as a product of many soft sets and afterwards we extend it to the HyperSoft Set. Similarly, the IndetermSoft Product is extended to the IndetermHyperSoft Set. We also present several applications of the Soft Set Product to Fuzzy (and fuzzy-extensions) Soft Set Product and to IndetermSoft Set and IndetermHyperSoft Set.

Thomas Reid's philosophy of mind, epistemology, and philosophy of language all rely on his account of signs and signification. On Reid's view, some entities play a role of indicating other entities to our minds. In some cases, our sensitivity to this indication is learned through experience, whereas in others, the sensitivity is built in to our natural constitutions. Unlike representation, which was presumed to depend on resemblances and necessary connections, signification is the sort of relationship that can occur without (...) any intrinsic ties between the sign and the thing signified. Of particular interest is the priority Reid gives to natural signs. Reid deploys his robust account of natural signs in a way that allows him to sidestep some skeptical worries common in the early modern period, as well as in grounding “artificial” human languages like English or Cantonese on a more basic human capacity for communication, that is, itself, the result of our sensitivity to natural signs of other people's minds. (shrink)

The paper introduces and utilizes a few new concepts: “nonstandard Peano arithmetic”, “complementary Peano arithmetic”, “Hilbert arithmetic”. They identify the foundations of both mathematics and physics demonstrating the equivalence of the newly introduced Hilbert arithmetic and the separable complex Hilbert space of quantum mechanics in turn underlying physics and all the world. That new both mathematical and physical ground can be recognized as information complemented and generalized by quantum information. A few fundamental mathematical problems of the present such as Fermat’s (...) last theorem, four-color theorem as well as its new-formulated generalization as “four-letter theorem”, Poincaré’s conjecture, “P vs NP” are considered over again, from and within the new-founding conceptual reference frame of information, as illustrations. Simple or crucially simplifying solutions and proofs are demonstrated. The link between the consistent completeness of the system mathematics-physics on the ground of information and all the great mathematical problems of the present (rather than the enumerated ones) is suggested. (shrink)

In this paper one introduces for the first time the IndetermSoft Set, as extension of the classical (determinate) Soft Set, that deals with indeterminate data, and similarly the HyperSoft Set extended to IndetermHyperSoft Set, where ‘Indeterm’ stands for ‘Indeterminate’ (uncertain, conflicting, not unique outcome). They are built on an IndetermSoft Algebra that is an algebra dealing with IndetermSoft Operators resulted from our real world. Afterwards, the corresponding Fuzzy / Intuitionistic Fuzzy / Neutrosophic / and other fuzzy-extension IndetermSoft Set & IndetermHyperSoft (...) Set are presented together with their applications. (shrink)

As is clear from the multiple references to knowledge in the proemium of fragment B1, Parmenides presented himself to his audiences as one who had achieved a profound insight into the nature of ‘what-is’. In support of this claim he conducted an elenchos or ‘testing’ of the ways of inquiry available for thinking, in the process revealing a set of sêmata or ‘signs’ indicating that what-is an eternal, indivisible, and unchanging plenum. In each of these respects, Parmenides was speaking (...) the language of discovery heard elsewhere in early Greek poetry. Similarly, his claim that we can neither learn nor know about what-is-not (hence must not say or think ‘it is not’) was justified by the ordinary meaning of the ancient Greek verbs for learning and knowing. Strikingly, Parmenides’ revisionary metaphysics rested in large measure on a widely shared view of what can be learned, known, and made known to others. -/- . (shrink)

Sign Language Recognition (SLR) aims to translate sign language into text or speech in order to improve communication between deaf-mute people and the general public. This task has a large social impact, but it is still difficult due to the complexity and wide range of hand actions. We present a novel 3D convolutional neural network (CNN) that extracts discriminative spatial-temporal features from photo datasets. This article is about classification of sign languages are not universal and are usually not mutually intelligible (...) although there are also similarities among different sign languages. They are the foundation of local Deaf cultures and have evolved into effective means of communication. Although signing is primarily used by the deaf and hard of hearing, hearing people also use it when they are unable to speak, when they have difficulty speaking due to a health condition or disability (augmentative and alternative communication), or when they have deaf family members, such as children of deaf adults. In this article we use the 43500 image in the dataset in size 64*64 pixel by use CNN Architecture and achieved 100% accuracy. (shrink)

Philosophical counselling is typically conceptualised as a praxis going beyond academic and theoretical philosophy. However, two problems soon follow, namely the lack of agreed-upon methods and a substantial neglect of different philosophical traditions informing its practice. In this article, I propose reconceptualising philosophical counselling as a distinct method through which academic philosophy can be practised. This allows me to introduce an understanding of African philosophy, inspired by African philosophers Chimakonam and Serequeberhan, that might encourage the philosophical counsellor to render academic (...) philosophy more applicable to the counselee. Moreover, it allows for embodied voices talking from an embedded African lifeworld to create new and more relevant concepts that emerge from that lifeworld. (shrink)

American Sign Language, or ASL as its acronym is commonly known, is a fascinating language, and many people outside of the Deaf community have begun to recognize its value and purpose. It is a visual language consisting of coordinated hand gestures, body movements, and facial expressions. Sign language is not a universal language; it varies by country and is heavily influenced by the native language and culture. The American Sign Language alphabet and the British Sign Language alphabet are completely contrary. (...) Fingerspelling is one-handed in ASL and two-handed in BSL, with the exception of the letter C. AI technologies, particularly deep learning, can play an important role in breaking down communication barriers between deaf or hearing-impaired people and other communities, significantly contributing to their social inclusion. Recent advances in sensing technologies and AI algorithms have paved the way for the development of a wide range of applications aimed at meeting the needs of the deaf and hearing-impaired communities. To that end, the purpose of this paper is By attempting to translate sign language using artificial intelligence algorithms, we focused in this paper on a transfer learning technique based on deep learning using a ResNet algorithm and compared it to previous papers in which we used VGG19[1]and mobileNet [2], where we get in the ResNet algorithm on the degree of Accuracy 93,48% e number of images (43500 in the dataset in size 64*64 pixel ) and the data split training data into training dataset (70%) and validation dataset(15%) and testing dataset(15%) and 20 epoch. (shrink)

W. V. Quine’s first philosophical monograph, Word and Object, is widely recognized as one of the most influential books of twentieth century philosophy. Notes, letters, and draft manuscripts at the Quine Archives, however, reveal that Quine was already working on a philosophical book in the early 1940s; a project entitled Sign and Object. In this paper, I examine these and other unpublished documents and show that Sign and Object sheds new light on the evolution of Quine’s ideas. Where “Two Dogmas (...) of Empiricism” is usually considered to be a turning point in Quine’s development, this paper redefines the place of ‘Two Dogmas’ in his oeuvre. Not only does Quine’s book project reveal that his views were already fairly naturalistic in the early 1940s ; Sign and Object also unearths the steps Quine had to take in maturing his perspective; steps that will be traced in the second half of this paper. (shrink)

Set-theoretic pluralism is an increasingly influential position in the philosophy of set theory (Balaguer [1998], Linksy and Zalta [1995], Hamkins [2012]). There is considerable room for debate about how best to formulate set-theoretic pluralism, and even about whether the view is coherent. But there is widespread agreement as to what there is to recommend the view (given that it can be formulated coherently). Unlike set-theoretic universalism, set-theoretic pluralism affords an answer to Benacerraf’s epistemological challenge. The purpose of this paper is (...) to determine what Benacerraf’s challenge could be such that this view is warranted. I argue that it could not be any of the challenges with which it has been traditionally identified by its advocates, like of Benacerraf and Field. Not only are none of the challenges easier for the pluralist to meet. None satisfies a key constraint that has been placed on Benacerraf’s challenge. However, I argue that Benacerraf’s challenge could be the challenge to show that our set-theoretic beliefs are safe – i.e., to show that we could not have easily had false ones. Whether the pluralist is, in fact, better positioned to show that our set-theoretic beliefs are safe turns on a broadly empirical conjecture which is outstanding. If this conjecture proves to be false, then it is unclear what the epistemological argument for set-theoretic pluralism is supposed to be. (shrink)

This article analyses the use of signs (in a semiotic sense) in the analysis of Teresa of Avila's book, The Interior Castle. It takes one through the various levels of the castle, which stands as a sign for contemplation. Exploring Avila's creative use of imagery and language, it focus on what these signs (as pertaining to American semiotics and Charles S. Peirce) come to signify within Teresa's mental construction of the castle as a road to pure contemplation, in (...) the Catholic tradition. (shrink)

Philosophers of science since Nagel have been interested in the links between intertheoretic reduction and explanation, understanding and other forms of epistemic progress. Although intertheoretic reduction is widely agreed to occur in pure mathematics as well as empirical science, the relationship between reduction and explanation in the mathematical setting has rarely been investigated in a similarly serious way. This paper examines an important particular case: the reduction of arithmetic to set theory. I claim that the reduction is unexplanatory. In defense (...) of this claim, I offer evidence from mathematical practice, and I respond to contrary suggestions due to Steinhart, Maddy, Kitcher and Quine. I then show how, even if set-theoretic reductions are generally not explanatory, set theory can nevertheless serve as a legitimate foundation for mathematics. Finally, some implications of my thesis for philosophy of mathematics and philosophy of science are discussed. In particular, I suggest that some reductions in mathematics are probably explanatory, and I propose that differing standards of theory acceptance might account for the apparent lack of unexplanatory reductions in the empirical sciences. (shrink)

In this paper, we introduce the plithogenic set (as generalization of crisp, fuzzy, intuitionistic fuzzy, and neutrosophic sets), which is a set whose elements are characterized by many attributes (parameters)’ values. An attribute value v has a corresponding (fuzzy, intuitionistic fuzzy, or neutrosophic) degree of appurtenance d(x,v) of the element x, to the set P, with respect to some given criteria. In order to obtain a better accuracy for the plithogenic aggregation operators in the plithogenic set, and for a (...) more exact inclusion (partial order), a (fuzzy, intuitionistic fuzzy, or neutrosophic) contradiction (dissimilarity) degree is defined be-tween each attribute value and the dominant (most important) attribute value. The plithogenic intersection and union are linear combinations of the fuzzy operators tnorm and tconorm, while the plithogenic complement, inclusion (inequality), equality are influenced by the attribute values contradiction (dissimilarity) degrees. This article offers some examples and applications of these new concepts in our everyday life. (shrink)