Abstract Introduction Logically valid deductive arguments are clear examples of abstract recursive computational proce‐ dures on propositions or on probabilities. However, it is not known if the cortical time‐consuming inferential pro‐ cesses in which logical arguments are eventually realized in the brain are in fact physically different from other kinds of inferential processes. Methods In order to determine whether an electrical EEG discernible pattern of logical deduction exists or not, a new experimental paradigm is proposed contrasting logically valid and invalid (...) inferences with exactly the same content (same premises and same relational variables) and distinct logical complexity (propositional truth‐functional operators). Electroencephalographic signals from 19 subjects (24.2 ± 3.3 years) were acquired in a two‐condition para‐ digm (100 trials for each condition). After the initial general analysis, a trial‐by‐trial approach in beta‐2 band allowed to uncover not only evoked but also phase asynchronous activity between trials. Results showed that (i) deductive inferences with the same content evoked the same response pattern in logically valid and invalid conditions, (ii) mean response time in logically valid inferences is 61.54% higher, (iii) logically valid inferences are subjected to an early (400 ms) and a late reprocessing (600 ms) verified by two distinct beta‐2 activa‐ tions (p‐value < 0,01, Wilcoxon signed rank test). Conclusion We found evidence of a subtle but measurable electrical trait of logical validity. Results put forward the hypothesis that some logically valid deductions are recursive or computational cortical events. Keywords Beta‐2 band, Evoked potentials, Induced potentials, Deductive inference, Logical validity, Cortical bases of logical reasoning. (shrink)

Complex human reasoning involves minimal abilities to extract conclusions implied in the available information. These abilities are considered “deductive” because they exemplify certain abstract relations among propositions or probabilities called deductive arguments. However, the electrophysiological dynamics which supports such complex cognitive pro- cesses has not been addressed yet. In this work we consider typically deductive logico- probabilistically valid inferences and aim to verify or refute their electrophysiological functional connectivity differences from invalid inferences with the same content (same relational variables, same (...) stimuli, same relevant and salient features). We recorded the brain electrophysiological activity of 20 participants (age 1⁄4 20.35 ± 3.23) by means of an MEG system during two consecutive reasoning tasks: a search task (invalid condition) without any specific deductive rules to follow, and a logically valid deductive task (valid condition) with explicit deductive rules as instructions. We calculated the functional connectivity (FC) for each condition and conducted a seed-based analysis in a set of cortical regions of interest. Finally, we used a cluster-based permutation test to compare the dif- ferences between logically valid and invalid conditions in terms of FC. As a first novel result we found higher FC for valid condition in beta band between regions of interest and left prefrontal, temporal, parietal, and cingulate structures. FC analysis allows a second novel result which is the definition of a propositional network with operculo-cingular, parietal and medial nodes, specifically including disputed medial deductive “core” areas. The experiment discloses measurable cortical processes which do not depend on content but on truth-functional propositional operators. These experimental novelties may contribute to understand the cortical bases of deductive processes. (shrink)

In *Engaging Capital Emotions,* Douglas Berman and Stephanos Bibas argue that emotion is central to understanding and evaluating the death penalty, and that the emotional case for the death penalty for child rape may be even stronger than for adult murder. Both the Berman and Bibas article and the subsequent Supreme Court decision in Kennedy v. Louisiana (striking down the death penalty for child rape) raise difficult questions about how to measure the heinousness of crimes other than murder, and about (...) the role the pain suffered by victims and victims' families should play in this inquiry. In this Reply, I agree with the authors on the importance of confronting emotion's role in capital punishment, for reasons I discuss in Part A. However, I disagree with their claim that the moral outrage evoked by child rape supports making it a capital crime. Part B explores the difficulties of using the existence of moral outrage as a measure of appropriate punishment. Part C argues that the penal system should not merely reflect moral outrage, but channel and educate it. It suggests that the availability of the death penalty may create an anchoring effect, communicating the message that the death penalty is the proper way to express moral outrage and to honor the worth of murder victims. It explores the consequences of this message. Section II focuses on the role of emotion in deciding whether child rape should be a capital crime. Part A considers the problematic role of victim harm in determining whether the death penalty is appropriate. It explores the question, raised in Kennedy v Louisiana, of whether the effect of a capital trial on child rape victims ought to be part of the calculus. Part B argues that there are three particular problems with allowing juries to sentence child rapists to death: the deleterious effect of anger and empathy, the problem of generic prejudice, and the issue of race. (shrink)

The Protein Ontology (PRO) is designed as a formal and principled Open Biomedical Ontologies (OBO) Foundry ontology for proteins. The components of PRO extend from a classification of proteins on the basis of evolutionary relationships at the homeomorphic level to the representation of the multiple protein forms of a gene, including those resulting from alternative splicing, cleavage and/or posttranslational modifications. Focusing specifically on the TGF-beta signaling proteins, we describe the building, curation, usage and dissemination of PRO. PRO provides a (...) framework for the formal representation of protein classes and protein forms in the OBO Foundry. It is designed to enable data retrieval and integration and machine reasoning at the molecular level of proteins, thereby facilitating cross-species comparisons, pathway analysis, disease modeling and the generation of new hypotheses. (shrink)

Social individuals are social entities having a distinctive individuality, often signaled by the use of a proper name to designate them. This article proposes an account of social individuals based on the notion of a mental file, understood as a repository of information about a single individual. First, I consider a variant of the puzzle of the ship of Theseus in which the object having problematic identity conditions is a social individual, namely, a rock band. Then, I argue that (...) we can figure out such identity conditions by considering the mental files concerning this band. In conclusion, I outline a version of social constructionism according to which the existence of social individuals like bands depends on mental files about them. (shrink)

A single-blind experiment was conducted on free-responsive spatially non-local perception of free-selective simple photographic targets. One author (the tasker) chose a photographic target not subjected to a priori compiling, and the other author (the perceiver) attempted to unconventionally perceive the target. Feedback was expected prior to a new target being selected. A hundred trials were completed over 11 months. Thirteen judges offered gradings that collectively projected an apparent information requisition yield (AIRY). The AIRY refers to two aspects of the matching (...) of a taskette (a target’s counterpart) with respect to the target based on fuzzy scales from 0% to 100%, graded with an increment of 10%. The type-I or “tangibility” aspect of matching assessed the extent of the resemblance of a taskette to the target in terms of the shape or structural details of the primary physical entity/event. The type-II or “intangibility” aspect of the matching assessed the degree of the reconstruction of a taskette to the target in terms of the feature or functionality of the predominant physical entity/event. A total of 6 taskettes received >50% grades in both type-I and type-II aspects of matching with their respective targets. This outcome may correspond to an effect size of 1.47 if the chance-expectation may give a benchmark proportion of 3 out of 100 trials producing >50% grades in both type-I and type-II aspects of matching. Patterns indicating target interference associated with two trials entail further investigation. The approaches offer new insights to quantifying the band-limited information throughputs of spatially non-local perception. (shrink)

a simple derivation of the effect induced from repeated measurements on quantum unstable systems is obtained by using the regularized incomplete beta - function .

Tarski’s Convention T—presenting his notion of adequate definition of truth (sic)—contains two conditions: alpha and beta. Alpha requires that all instances of a certain T Schema be provable. Beta requires in effect the provability of ‘every truth is a sentence’. Beta formally recognizes the fact, repeatedly emphasized by Tarski, that sentences (devoid of free variable occurrences)—as opposed to pre-sentences (having free occurrences of variables)—exhaust the range of significance of is true. In Tarski’s preferred usage, it is part (...) of the meaning of true that attribution of being true to a given thing presupposes the thing is a sentence. Beta’s importance is further highlighted by the fact that alpha can be satisfied using the recursively definable concept of being satisfied by every infinite sequence, which Tarski explicitly rejects. Moreover, in Definition 23, the famous truth-definition, Tarski supplements “being satisfied by every infinite sequence” by adding the condition “being a sentence”. Even where truth is undefinable and treated by Tarski axiomatically, he adds as an explicit axiom a sentence to the effect that every truth is a sentence. Surprisingly, the sentence just before the presentation of Convention T seems to imply that alpha alone might be sufficient. Even more surprising is the sentence just after Convention T saying beta “is not essential”. Why include a condition if it is not essential? Tarski says nothing about this dissonance. Considering the broader context, the Polish original, the German translation from which the English was derived, and other sources, we attempt to determine what Tarski might have intended by the two troubling sentences which, as they stand, are contrary to the spirit, if not the letter, of several other passages in Tarski’s corpus. (shrink)

Boundary colors are observed when light from a scene is dispersed by a prism or diffraction grating. We discovered that patterns with repeating black and white stripes can produce repeating bands of boundary colors with two hues. These hues are virtually constant as measured by chromaticity or CIELAB. We found seven cases of this kind using a new appearance model for boundary colors. The model correctly predicts that green and magenta bands recur as stripe widths and dispersion strength vary. The (...) first green/magenta case in the sequence traces out an accurate ellipse in XYZ color space. Green and magenta bands are prominent in supernumerary rainbows and interference rings, and we explain why that might be the case. The explanation is based on an interesting property of the visible spectrum. In addition to the green/magenta cases, the other cases are orange/cyan, yellowish-green/purple, and yellow/violet. The success of the boundary color appearance model implies that bands are perceived as if the wavelength responses of the cones were essentially independent, which contradicts the actual behavior of cones. (shrink)

De acuerdo algunos investigadores el ruido es concebido típicamente como factor perjudicial en el desempeño cognitivo afectando la percepción, toma de decisiones y la función motora. No obstante, en estudios recientes se asocia al ruido blanco con la concentración y la calma, por lo tanto, esta investigación busca establecer el impacto del ruido blanco binaural en el desempeño de la memoria de trabajo y visual a corto plazo, la actividad cerebral alfa – beta y la atención – meditación, mediante (...) el uso de dos estímulos auditivos con rangos de frecuencia de (100 a 450hz) y (100 a 750hz). Este estudio se realizó en la ciudad de Montes Claros, República de Brasil, donde se evaluó a siete participantes (n = 7) con una edad promedio de 36.71±, y dos grupos de edad (GP1) 21 a 30 y (GP2) 41 a 50 de escolaridad media a universitaria. Dentro del proceso experimental se realizaron pruebas de memoria visual a corto plazo mediante el uso de la batería de evaluación cognitiva general CAB de CogniFit™, así como el registro de actividades cerebrales mediante el uso de Electroencefalograma monopolar y los algoritmos eSense™. Con los resultados obtenidos y mediante el uso de pruebas estadísticas podemos inferir que el ruido blanco binaural con oscilaciones de 100 a 750 Hz contribuyeron con el rendimiento de la memoria visual de trabajo a corto plazo. (shrink)

based on organic materials can be mechanically exible to a large extent because of the loose intermolecular bonds in the nano-electrons created from them. Unlike these organic materials, minerals such as silicon, germanium, and gallium arsenide can be used in the structure of electronic devices only in crystalline states, and in this case, covalent bonds make exibility impossible in them. Makes. Properties such as strength, exibility, electrical conductivity, magnetic properties, color, reactivity, etc. Starting to change the properties of the material (...) by shrinking it depends more than anything on the type of material and the desired property. For example, by reducing the dimensions of a material, generally some mechanical properties of the material such as strength are improved. This increase in strength does not happen only in the range of a few nanometers, and the strength of materials of several tens and even hundreds of nanometers may be much higher than the large-scale mass material. On the other hand, the change of some properties such as color and magnetic properties may occur in dimensions of only a few nanometers. (shrink)

In some musical genres, professional performers play live shows many times a week. Arduous touring schedules bring encounters with wildly diverse audiences across many different performance ecologies. We investigate the kinds of creativity involved in such repeated live performance, kinds of creativity that are quite unlike songwriting and recording, and examine the central factors that influence musicians’ wellbeing over the course of a tour. The perspective of the professional musician has been underrepresented in research on relations between music and wellbeing, (...) with little attention given to the experience of touring. In this case study, we investigate influences on positive and negative performance experiences for the four professional musicians of Australian pop/rock band Cloud Control. Geeves conducted intensive cognitive ethnographic fieldwork with Cloud Control members over a two-week national Australian tour for their second album, Dream Cave (2013). Adapting a Grounded Theory approach to data analysis, we found the level of wellbeing musicians reported and displayed on tour to be intimately linked to their creative performance experiences through the two emergent, overarching and interdependent themes of Performance Headspace (PH) and Connection with Audience (CA). We explore these themes in detail and provide examples to demonstrate how PH and CA can feed off each other in virtuous ways that positively shape musicians’ wellbeing, or loop in vicious ways that negatively shape musicians’ wellbeing. We argue that their creative practice, in thus re-enacting musical performance afresh in each venue’s distinctive setting, emerges within unique constraints each night, and is in a sense a co-creation of the crowd and the band. (shrink)

Aus dem vielfältigen Werk von Hermann von Helmholtz versammelt diese Ausgabe die im engeren Sinne philosophischen Abhandlungen, vor allem zur Wissenschaftsphilosophie und Erkenntnistheorie, sowie Vorträge und Reden, bei denen der Autor seine Ausnahmestellung im Wissenschaftsbetrieb nutzte, um die Wissenschaften und ihre Institutionen in der bestehenden Form zu repräsentieren und zu begründen. Ein Philosoph wollte Helmholtz nicht sein, aber er legte der philosophischen Reflexion wissenschaftlicher Erkenntnis und wissenschaftlichen Handelns große Bedeutung bei. Vor allem bezog er, in der Regel ausgehend von seinen (...) fachwissenschaftlichen Forschungen, in den verschiedensten Kontexten zu erkenntnistheoretischen und methodologischen Problemen der Wissenschaften Stellung. Bereits »Ueber die Erhaltung der Kraft« (1847) lässt erkennen, wie verwoben naturwissenschaftliche Grundlagenforschung und philosophische Grundlagenreflexion in seinem Werk sind. Die aus den frühen sinnesphysiologischen Forschungen hervorgegangene empiristische Wahrnehmungslehre trug ihm den Ruf ein, ein maßgeblicher Vertreter des Neukantianismus zu sein. Spätere Arbeiten v.a. zur Geometrie und Arithmetik – das zeigt die vorliegende Ausgabe – stellen jedoch eine radikale Absage an den konstitutiven Kern des Kantianismus (nämlich die Existenz synthetischer Urteile a priori) dar. Helmholtz’ philosophische Beiträge sind bisher in ihrer Vollständigkeit nicht annähernd so gut zugänglich wie sein naturwissenschaftliches Werk. Die Ausgabe enthält außerdem bibliographische Vorberichte zur Einordnung, detaillierte Namens- und Sachregister sowie mit 575 Einträgen für den Zeitraum zwischen 1842 und 2012 die erste umfassende Bibliographie von Helmholtz verfasster Werke überhaupt. »Ich glaube, dass der Philosophie nur wieder aufzuhelfen ist, wenn sie sich mit Ernst und Eifer der Untersuchung der Erkenntnissprocesse und der wissenschaftlichen Methode zuwendet. Da hat sie eine wirkliche und berechtigte Aufgabe.« Helmholtz in einem Brief um 1875. (shrink)

In recent decades, interest in the history and philosophy of the natural sciences has increased significantly. This interest has made scholars aware of the existing knowledge gap in these areas and has brought a kind of 'pressure' for more articles and books on the subject. Indeed, it also motivates academics to start new projects related to these disciplines. Volumes like this are much needed for scholars in the field, given the high amount of information they contain. This rich volume aims (...) at stimulating the field by presenting current research papers on Avicenna's influence on the fields of physics and cosmology. In order to achieve this goal, this work contains thirteen articles related to the reception of the Persian philosopher's thought in these areas in the Middle Ages. The book revolves around the three different languages and cultures which were crucial for the reception of Avicenna's thought. Hence, the volume is arranged in three main sections focusing on the Arabic, Hebrew and Latin traditions. It also contains an Index of Avicenna's Works with Passages Cited and an Index of Names. The introduction is rather short compared to other sections of the book. It covers the general topics presented in the volume. The first six chapters deal with the Arabic tradition ; the next two have to do with the Hebrew reception of Avicenna, and the last five analyse the Latin reception of Avicenna's physics and cosmology. (shrink)

The data analyzed in this paper are part of the results described in Bueno et al. (2000). Three cytogenetics endpoints were analyzed in three populations of a species of wild rodent – Akodon montensis – living in an industrial, an agricultural, and a preservation area at the Itajaí Valley, State of Santa Catarina, Brazil. The polychromatic/normochromatic ratio, the mitotic index, and the frequency of micronucleated polychromatic erythrocites were used in an attempt to establish a genotoxic profile of each area. It (...) was assumed that the three populations were in the same conditions with respect to the influence of confounding factors such as animal age, health, nutrition status, presence of pathogens, and intra- and inter-populational genetic variability. Therefore, any differences found in the endpoints analyzed could be attributed to the external agents present in each area. The statistical models used in this paper are mixtures of negative-binomials and Poisson variables. The Poisson variables are used as approximations of binomials for rare events. The mixing distributions are beta densities. The statistical analyzes are under the bayesian perspective, as opposed to the frequentist ones often considered in the literature, as for instance in Bueno et al. (2000). (shrink)

Dieser Band versammelt Beiträge zu den drei klassischen Disziplinen der Philosophie – dem Wahren, dem Guten, dem Schönen. Ihre Autoren zeichnet aus, dass sie aus dem akademischen Umfeld Michael Sukales zu seiner Zeit am Institut für Philosophie an der Carl-von-Ossietzky-Universität Oldenburg stammen. Ihm ist dieses Buch zum Abschied von seiner aktiven Lehrtätigkeit in Oldenburg gewidmet. Die thematische Vielfalt der enthaltenen Texte spiegelt die Bandbreite seines philosophischen Schaffens wider.

Dieser Band stellt die erste Fortsetzung der 2013 begonnenen Publikation zur „Wirtlichen Ökonomie“ dar. Er dient der sich fortsetzenden Frage nach der Wirtlichkeit. Zu dieser Frage gehört es, das Ökonomische aus einer notwendig gewordenen Zurückhaltung gegenüber dem methodischen Vorgriff der modernen Wirtschaftswissenschaften zu denken. Die Zurückhaltung verleiht, indem sie den Fragebereich der Wirtlichkeit eröffnet, den hier versammelten Beiträgen ihren wahren Zusammenhang.

Der Band fragt nach der Rolle des Körpers im Recht. Vertreter:innen der Philosophie, Theologie und Rechtswissenschaft untersuchen ein vielseitiges und komplexes Spektrum an Fragen, die sich aus dem Verhältnis der Begriffe „Recht" und „Körper" ergeben. In welcher rechtlichen Gestalt tritt ein (menschliches) Rechtssubjekt als Körper auf? Wie wird seine Körperlichkeit vom Recht erfasst, geschützt und normativ bestimmt und gestaltet? Was unterscheidet aus einer rechtlichen Perspektive den menschlichen vom tierischen Körper? Kann der menschliche Körper als Eigentum verstanden werden oder gehorcht (...) er einer fundamental anderen Logik? (shrink)

Biomedical ontologies are emerging as critical tools in genomic and proteomic research where complex data in disparate resources need to be integrated. A number of ontologies exist that describe the properties that can be attributed to proteins; for example, protein functions are described by Gene Ontology, while human diseases are described by Disease Ontology. There is, however, a gap in the current set of ontologies—one that describes the protein entities themselves and their relationships. We have designed a PRotein Ontology (PRO) (...) to facilitate protein annotation and to guide new experiments. The components of PRO extend from the classification of proteins on the basis of evolutionary relationships to the representation of the multiple protein forms of a gene (products generated by genetic variation, alternative splicing, proteolytic cleavage, and other post-translational modification). PRO will allow the specification of relationships between PRO, GO and other OBO Foundry ontologies. Here we describe the initial development of PRO, illustrated using human proteins from the TGF-beta signaling pathway. (shrink)

In a recent paper, Pruss proves the validity of the rule beta-2 relative to Lewis’s semantics for counterfactuals, which is a significant step forward in the debate about the consequence argument. Yet, we believe there remain intuitive counter-examples to beta-2 formulated with the actuality operator and rigidified descriptions. We offer a novel and two-dimensional formulation of the Lewisian semantics for counterfactuals and prove the validity of a new transfer rule according to which a new version of the consequence (...) argument can be formulated. This new transfer rule is immune to the counter-examples involving the actuality operator and rigidified descriptions. However, we show that counter-examples to this new rule can also be generated, demanding that the Lewisian semantics be generalized for higher dimensions where counter-examples can always be generated. (shrink)

Dieser Band befasst sich mit einem wichtigen Aspekt der Ars didactica: Er diskutiert zwar keine neuen „Übersetzungsmethoden“, will aber dazu anregen, das Übersetzen als eine unverzichtbare Kulturtechnik zu lehren und zu lernen. Er will dazu ermuntern, das Übersetzen nicht auf die informationstheoretischen bzw. nachrichtentechnischen Vorgänge des Rekodierens und Dekodierens zu reduzieren, sondern als eine anspruchsvolle und bisweilen auch kreative Leistung ernst zu nehmen, seine ästhetische Dimension nicht aus den Augen zu verlieren und den Respekt vor dem Original erkennen zu (...) lassen. (shrink)

Der vorliegende Band intendiert die Herstellung von Unterrichtsmaterialien für Lehrer und Schüler, und zwar nicht aus einer fachspezifischen Perspektive, sondern als ein Projekt fachübergreifenden oder fächerübergreifenden Unterrichts. Wir lassen uns von der Vorstellung leiten, dass komplexe Probleme, die ihren Ursprung in einer ebenso komplexen Gesellschaft haben, sich nicht mehr allein durch Spezialwissen lösen lassen. Vielmehr erfordert die gegenwärtige Situation vernetztes Wissen und Menschen, die Kompetenzen erworben haben, um an einer dynamischen Wissensgesellschaft zu partizipieren. Im Hintergrund steht dabei auch die (...) Vorstellung, dass die Anforderungen des Berufs- und Wirtschaftslebens zugleich ein lebenslanges Lernen erfordern. Es geht uns darum, alle paternalistischen oder moralistischen Implikationen zu vermeiden; vielmehr sollen Schüler in die Lage versetzt werden, eine eigenständige und damit nachhaltige Auffassung zu entwickeln. Um die Vielschichtigkeit und Komplexität der Bezüge eines jeden Faches und der Fächer untereinander abzubilden, werden die für die Dopingthematik besonders relevanten Fächer Sport, Biologie, Philosophie/Ethik, Religion und Sozialwissenschaften in einzelnen Modulen durch ausgewiesene Experten, die einen jeweils aktuellen fachdidaktischen und inhaltlichen Stand der Forschung garantieren, abgehandelt und didaktisch aufbereitet. Somit werden die Schwerpunkte Leistung und Kontrolle (Sport), biologische Manipulation (Biologie), ethische Urteilsfindung (Ethik/Bioethik), Selbst- und Weltbild (Religion), die gesellschaftliche sowie ökonomische Relevanz (Sozialwissenschaften) in ihrem transdisziplinären bzw. fächerübergreifenden Zusammenhang abgebildet und zugänglich gemacht. Jedes Modul enthält neben parallelen Themen (wie Gendoping) auch didaktische Hinweise und einige Anregungen für konkrete Anknüpfungspunkte zu den anderen Modulen. Durch diese fächerübergreifende Verständigung wird das didaktisch wesentliche Ziel erreicht, die Schüler zu einer reflektierten Bewertung der Dopingthematik zu befähigen und zu motivieren. (shrink)

Propositional dynamic logic is complete but not compact. As a consequence, strong completeness requires an infinitary proof system. In this paper, we present a short proof for strong completeness of $$\mathsf{PDL}$$ relative to an infinitary proof system containing the rule from [α; β n ]φ for all $$n \in {\mathbb{N}}$$, conclude $$[\alpha;\beta^*] \varphi$$. The proof uses a universal canonical model, and it is generalized to other modal logics with infinitary proof rules, such as epistemic knowledge with common knowledge. Also, (...) we show that the universal canonical model of $$\mathsf{PDL}$$ lacks the property of modal harmony, the analogue of the Truth lemma for modal operators. (shrink)

The world’s first COVID-19 human challenge trial using the D614G strain of SARS-CoV-2 is underway in the United Kingdom. The Wellcome Trust is funding challenge stock preparation of the Beta variant (B.1.351) for a follow-up human challenge trial, and researchers at Imperial College London are considering conducting that trial. However, little has been written thus far about the ethical justifiability of human challenge trials with SARS-CoV-2 variants of concern. While vaccine resistance as such does not increase risks for volunteers (...) in COVID-19 challenge trials, we explore two specific characteristics of some variants that may initially be thought to make such trials unethical and conclude that SARS-CoV-2 variant challenge trials can remain ethical. (shrink)

Dieser inter- und multidisziplinäre Band bietet einen Querschnitt durch die wissenschaftliche Auseinandersetzung mit dem über hundert Jahre zurückliegenden Armenier-Genozid, der bis heute von den türkischen Nachfolgeregierungen offiziell geleugnet wird. Beiträge aus unterschiedlichen Disziplinen weisen auf spezifische Probleme hin, die mit der Aufarbeitung dieses Genozids zusammenhängen: Beginnend mit einem (rechts-)historischen Teil über das Verbrechen sowie dessen zeitgenössische Bewertung, hin zu den direkten und indirekten psychologischen Folgen des Verbrechens bis heute, sowie moralphilosophische und rechtliche Fragestellungen in Bezug auf die Leugnung des (...) Genozids. (shrink)

Der interdisziplinär ausgerichtete Band zielt nicht auf die Korrektur oder Ergänzung des herrschenden ökonomischen Paradigmas. Vielmehr gilt es neu zu bestimmen, was ökonomisches Wissen, was seine Quellen und Methoden sein sollen. Wie lässt sich eine solche Neubestimmung im Rückgang auf Werke der Dichtung und Kunst gewinnen? Welche fruchtbaren Impulse können aus interkulturellen Aspekten hervorgehen? Sind klassische philosophische Positionen überhaupt noch relevant für aktuelle ökonomische Problemstellungen und, wenn ja, in welcher Weise? Somit wird die weithin bestehende Akzeptanz, mit der jenem (...) Paradigma und dem Problem seines Wirklichkeitsbezugs begegnet wird, in Frage gestellt. (shrink)

The American rock band KISS is notorious. Its notoriety derives not only from the band’s otherworldly costumes (except for of course during the unmasked period), the fact that they were inducted into the Rock and Roll Hall of Fame, their numerous hit records or the amazing stage theatrics and pyrotechnics of their live shows. It’s also related to the band’s constantly changing makeup (and I don’t mean the kind on their faces!). Of the four members, only Paul (...) Stanley and Gene Simmons were fixtures. With so many changes to the band’s composition, has KISS always remained the same band? Some see this head-scratcher as roughly similar to a conundrum in philosophical metaphysics (that’s the area of philosophy addressing problems of existence): the puzzle of Theseus’s ship. (shrink)

Higher - dimensional calculus and integral transformation play crucial roles in advancing our understanding of complex systems in mathematics and theoretical physics . Integral transformations are instrumental in simplifying complex differential equations, enabling the resolution of multi - dimensional problems that arise in various scientific fields . This paper aims to delve into a specific higher - dimensional integral transformation defined by the axioms \(F[q, s, l, \alpha]\) and \(G[q, s, l, \beta, c]\) . We start by outlining the (...) axioms which define the functions \(F\) and \(G\) . Specifically, Axiom 1 defines \(F\) as a function of four variables : \(q\), \(s\), \(l\), and \( \alpha\), whereas Axiom 2 defines \(G\) as a function that additionally includes variables \( \beta\) and \(c\) . Axiom 3 relates \(h\) and \(l\) via a sine function . The core of our investigation is the integral transformation expressed as a five - dimensional integral involving \(G\) and proving its equivalence to \(F\), provided a specific condition on \(c\) holds . We approach this problem by first deriving the expression for \(c\) through detailed differentiation of \(F\) and equating it to \(G\) . The derivation involves advanced calculus techniques and symbolic mathematics to solve the resulting equations . We then verify the derived expression for \(c\) by substituting it back into the relationship between \(F\) and \(G\), ensuring that the equality holds under integral transformation . Finally, to corroborate our findings, we employ visualizations through multidimensional contour plots to illustrate the relationship between the derived expressions . This provides an intuitive confirmation of the mathematical consistency and validity of the transformation . This paper contributes to the field by providing a nuanced and detailed examination of higher - dimensional integral transformations and their underlying mathematical structures . The results have potential implications for theoretical physics, particularly in areas involving complex systems and multi - dimensional analyses . (shrink)

Das Thema dieses Bandes ist die Frage, ob die Wissenschaftstheorie eine normative Disziplin ist. Zunächst überrascht die Frage, denn für viele Wissenschaftstheoretiker ist die Antwort ein klares „Ja“; sie halten es für einen Allgemeinplatz, dass die Wissenschaftstheorie ein normatives Unternehmen ist. Bei genauerem Hinsehen stellt sich jedoch heraus, dass die Frage unterschiedliche Interpretationen zulässt, die einzeln diskutiert werden müssen. Dies geschieht im ersten Abschnitt. Im zweiten Abschnitt suchen wir nach möglichen Erklärungen dafür, warum die Wissenschaftstheorie bisher bei dem Projekt, eine (...) allseits akzeptable Methodologie wissenschaftlichen Schließens zu formulieren und zu begründen, so wenig Erfolg hatte. Eine mögliche Erklärung für den ausbleibenden Erfolg ist der Partikularismus, wonach Methoden keine allgemeine, sondern nur eine lokale, bereichsabhängige Gültigkeit haben. Im dritten Abschnitt wollen wir an Hand des Bayesianismus zeigen, dass die Methodologie doch nicht so schlecht da steht, wie es zunächst den Anschein hat. Der Bayesianismus ist für viele Wissenschaftstheoretiker der aussichtsreichste Kandidat für eine allgemeine Theorie induktiven Räsonierens. Wir besprechen seine Vorzüge, stellen aber auch dar, welche Konzessionen er an den Partikularismus machen muss. (shrink)

Sogo/Gakuryu Ishii is one of the pioneers of the punk/cyberpunk movement in Japanese cinema. Though his style changed throughout his career, his early films have been a great influence to filmmakers around the world. His unique filmic style presents questions, observations and interpretations regarding the role of violence as normalized in the daily lives of heavily marginalized punk youth portrayed in an amplified and stylized cyberpunk Japan. What is so captivating about Ishii's style and motivation is that he was not (...) only a filmmaker interested in making embellished political or social commentary, Ishii was also part of the emerging punk movement in Japan and several musicians of punk rock bands were also involved in his films. My main aim in my inquiry into Ishil's early films involves two parts regarding the same concept. The first is the ethical issues that arise both with portrayal of violence in films as well as the intention of such an endeavor in general. The second part is the way in which violence is made to be part of the film in terms of form and style. This may be interpreted as either glorifying and stylizing violence or showing that violence is nothing but a destructive force that the outcasts of society may not be able to escape. To the last statement Ishii seems to be silent but very active. What I mean by this is that the simplistic plot-lines of his early films are contrasted by heavy punk music, fast editing, constant moving camera and rage, fear and disappointment in the faces of the anti-heroes. (shrink)

The project of “public reason” claims to offer an epistemological resolution to the civic dilemma created by the clash of incompatible options for the rational exercise of freedom adopted by citizens in a diverse community. The present Article proposes, via consideration of a contrast between two classical accounts of dialectical reasoning, that the employment of “public reason,” in substantive due process analysis, is unworkable in theory and contrary to more reflective Supreme Court precedent. Although logical commonalities might be available to (...) pick out from the multitude of particularized accounts of what constitutes “civic order,” no “public reason” so derived could adequately capture - and thus be able to secure in a practical sense - any single determinate civic order, much less one that would be consistent with all citizens' conceptions of public order. Part I of this Article raises a number of issues for consideration relating to the epistemology of law and focuses especially on the concept of public reason and its critique. Part II addresses alternative approaches to legal reasoning suggested by classical accounts of practical reasoning and virtue theory and considers the operation of such legal analysis outside the area of substantive due process; Part III analyzes post-Lawrence case law confirming the dilemma created by the Supreme Court's ambiguous approaches to substantive due process and concludes that only one interpretation - that articulated fully in Washington v. Glucksberg and given lip service in Lawrence v. Texas - provides a method for resolving novel substantive due process challenges that is philosophically sound as well as historically coherent. Rather than perpetuating a fiction that denies the propriety of lawmaking unless based on principles that all citizens can rationally agree upon, an appropriate model of substantive due process analysis recognizes that law must inevitably be based upon principles that cannot be agreed upon by all citizens in virtue of rationality alone. -/- Abstract Footnotes (291) Beta -/- Revise My Submission -/- -/- One-Click Download | Share | Email | Add to Briefcase -/- Facebook | Twitter | Digg | Del.icio.us | CiteULike | Permalink Using the URL or DOI link below will ensure access to this page indefinitely -/- Based on your IP address, your paper is being delivered by: New York, USA Processing request. [Processing request.] Illinois, USA Processing request. [Processing request.] Brussels, Belgium Processing request. [Processing request.] Seoul, Korea Processing request. [Processing request.] California, USA Processing request. [Processing request.] -/- If you have any problems downloading this paper, please click on another Download Location above, or view our FAQ File name: SSRN-id1004757. ; Size: 424K -/- Sample Cover You will receive a black and white printed and perfect bound version of this document in 8 1/2 x 11 inch format, with glossy color front and back covers. Currently shipping to the US addresses only. Your order will be shipped within three business days. Quantity: Total Price = $0.50 plus shipping (U.S. Only) -/- If you have any problems with this purchase, please email [email protected] or call 1-585-442-8170. Reason's Freedom and the Dialectic of Ordered Liberty -/- Edward C. Lyons University of Notre Dame Law School -/- Cleveland State Law Review, Vol. 55, p. 157, 2007 -/- Abstract: The project of "public reason" claims to offer an epistemological resolution to the civic dilemma created by the clash of incompatible options for the rational exercise of freedom adopted by citizens in a diverse community. The present Article proposes, via consideration of a contrast between two classical accounts of dialectical reasoning, that the employment of "public reason," in substantive due process analysis, is unworkable in theory and contrary to more reflective Supreme Court precedent. Although logical commonalities might be available to pick out from the multitude of particularized accounts of what constitutes "civic order," no "public reason" so derived could adequately capture - and thus be able to secure in a practical sense - any single determinate civic order, much less one that would be consistent with all citizens' conceptions of public order. -/- Part I of this Article raises a number of issues for consideration relating to the epistemology of law and focuses especially on the concept of public reason and its critique. Part II addresses alternative approaches to legal reasoning suggested by classical accounts of practical reasoning and virtue theory and considers the operation of such legal analysis outside the area of substantive due process; Part III analyzes post-Lawrence case law confirming the dilemma created by the Supreme Court's ambiguous approaches to substantive due process and concludes that only one interpretation - that articulated fully in Washington v. Glucksberg and given lip service in Lawrence v. Texas - provides a method for resolving novel substantive due process challenges that is philosophically sound as well as historically coherent. -/- Rather than perpetuating a fiction that denies the propriety of lawmaking unless based on principles that all citizens can rationally agree upon, an appropriate model of substantive due process analysis recognizes that law must inevitably be based upon principles that cannot be agreed upon by all citizens in virtue of rationality alone. -/- Keywords: substantive due process, practical reason, public reason, Rawls, Casey, Lawrence, Glucksberg, Plato, Aristotle, Kant, Hegel, dialectic, autonomy, freedom -/- . (shrink)

Indem dieser Band sich auf das Verhältnis von Naturerkennen und Natursein konzentriert, thematisiert er einen wesentlichen Ausschnitt aus dem weiten Spektrum von Böhmes philosophischer Arbeit. Um die Naturthematik möglichst breit zu entfalten und für Querverbindungen offenzuhalten, ist der vorliegende Band in drei Abschnitte gegliedert. Im ersten Abschnitt stehen Charakter und Reichweite der wissenschaftlichen Erkenntnis von Natur im Mittelpunkt. Der zweite Teil des Bandes stellt alternative Perspektiven auf Natur vor. Im dritten Teil schließlich stehen der Mensch und sein Verhältnis (...) zu sich selbst im Mittelpunkt der Untersuchungen. Inhaltsverzeichnis Krohn, Wolfgang: Wissenschaftsentwicklung zwischen Dezentrierung und Dekonstruktion. Stehr, Nico: Von den Grenzen der Macht wissenschaftlicher Erkenntnis. Schäfer, Wolf: Zweifel am Ende des Baconschen Zeitalters. Kamper, Dietmar: Wissen ist Ohnmacht. Macht ist Unwissen. Gamm, der Technik. Janich, Peter: Zeit und Natur. Kimmerle, Heinz: »Es ist Zeit, daß es Zeit wird«. Wie kann Zeit Zeit werden? Schiemann, Gregor: Natur auf dem Rückzug. Zur Relevanz der aristotelischen Unterscheidung von Natur und Technik. Hauskeller, Michael: Ist Schönheit eine Atmosphäre?. Zur Bestimmung des landschaftlich Schönen. Schmitz, Hermann: Situationen und Atmosphären. Zur Ästhetik und Onthologie bei Gernot Böhme. Rehmann-Sutter, Christoph: Über Relationalität. Was ist das »Ökologische« in der Naturästhetik? Meyer-Abich, Klaus Michael: Erinnerung an die natürliche Mitwelt. Andreas-Griesebach, Manon: Idee plus Erfahrung. Goethes Begründung eines neuen Typs von Naturwissenschaft. Engelhardt, Dietrich von: Madame de Stael über Naturphilosophie, Naturwissenschaft und Medizin in De l'Allemagne. Deneke, Michael: Schramm, Engelbert: »Soziale Naturwissenschaft«. Zwischen Sozialwissenschaften und Naturwissenschaften. Böhme, Hartmut: Enthüllen und Verhüllen des Körpers. Biblische, mythische und künstlerische Deutungen des Nackten. Lippe, Rudolf zur: Eine Logik des gestischen Wissens. Müller, Rudolf Wolfgang: Gernot Böhme - Anima naturaliter japonica. Hoffmann, Gisbert: Das menschliche Sein als mediales. Martens, Ekkehard: »Natürlich« denken?. Heideggers Pseudosokratismus als Irrationalismus. Fleischer, Helmut: Naturalität ohne Naturalismus. Zum lebensweltlichen Fundus jeder höheren Erkenntnis-Artistik. Gerhard: Technik als Medium. Grundlinien einer Philosophie. (shrink)

Die Beiträge dieses Bandes untersuchen die Logik schwieriger Grenzziehungen im Umwelt- und Technikrecht aus juristischer, philosophischer, sozial- und ingenieurswissenschaftlicher Perspektive. Sie sind aus der interdisziplinären Tagung "Unscharfe Grenzen im Umwelt- und Technikrecht" hervorgegangen, die im März 2011 an der RWTH Aachen stattgefunden hat.

This integral investigation explored phenomenological and neurophysiologic, individual and collective dimensions of Christian Trinitarian meditation experiences in a volunteer, convenience sample of 10 practicing Christians, 6 men and 4 women, with a mean age of 48 years and an age range from 21 to 85 years. Participants meditated for a minimum period of 15 minutes, during which neurophysiologic data in the form of electroencephalographic (EEG), electromyographic (EMG), blood volume pulse (BVP) and respiratory activity were recorded. A phenomenological analysis indicated that (...) the meditation process generally involved a movement from body to mind to spirit as evident in reports of an increasingly relaxed, contented and focused state of consciousness characterised by Christian Trinitarian imagery, wonder, surrender, peace, bliss, openness and formlessness. The neuropsychological findings indicated significant increases, from baseline to meditation recordings, in the alpha and beta range, accompanied by increasing mean trends in the theta and gamma range, and decreasing mean trends in the delta range, EMG, BVP and respiration. Integrative findings indicated the practical theological value of small doses of Christian Trinity meditation to enhance spiritual life for those forms of waking, thinking, conscious behaviour needed in everyday world involvement and healing. Findings were discussed in relation to further integrative investigations and interventions with practical theological implications. (shrink)

The Industrial Ontologies Foundry (IOF) was formed to create a suite of interoperable ontologies. Ontologies that would serve as a foundation for data and information interoperability in all areas of manufacturing. To ensure that each ontology is developed in a structured and mutually coherent manner, the IOF has committed to the tiered architecture of ontology building based on the Basic Formal Ontology (BFO) as top level. One of the critical elements of a successful tiered architecture build is the domain mid-level (...) ontologies. However, thus far there has been no mid-level manufacturing ontology that is based on BFO. The IOF has recently released the IOF Core version 1 beta to fill this gap. This paper documents the development process and gives an overview of the current content of the IOF Core. Finally, the paper describes how the IOF Core can be used as the basis for a more domain-specific Supply Chain Ontology. (shrink)

Der Titel des Bandes greift eine Frage auf, die im alltäglichen Umgang aufkam: die Frage nach analytischer Philosophie, vom Rücksitz eines Autos gestellt. Dieser Kontext bot den Anlass, eine Herangehensweise zu wählen, die bislang nicht üblich war: auszuprobieren, was eine Einbeziehung des Alltags und Umgangs erbringen könnte, ohne auf Komplexität zu verzichten. -/- Diese Öffnung hat zu überraschenden Ergebnissen geführt, die eine Weiterentwicklung der analytischen Philosophie erlauben, auch und in besonderer Weise theoretisch: Die Beachtung von umgangsprachlichem Verhalten kann dabei behilflich (...) sein, Sprache besser zu verstehen, als dies eine traditionelle wissenschaftsphilosophische Ausrichtung ermöglichen würde. -/- Die Beiträge zu diesem Band haben Kathrina Talmi, Reinhard Matern und Kai Pege eingebracht. (shrink)

This capstone is centered around the development of an efficient electronic property inventory system tailored for school assets, driven by the overarching objective of resource optimization to ensure equitable access to vital materials for all learners. The methodology follows the “ISSO” framework (Ignite, Strategize, Systematize, Operationalize), complemented by a Logical Framework. The project employs a homegrown digitalized system constructed through a waterfall model approach, which undergoes alpha and beta testing. The study’s analysis utilizes a t-Test to evaluate its impact. (...) The outcomes reveal that real-time property monitoring significantly enhances custodianship, while digitalization yields improvements in reliability, efficiency, and usability, effectively overhauling the conventional inventory process. The electronic system fosters stakeholder engagement, supporting communication, budget allocation, and audits. Comparative testing demonstrates clear advantages over traditional manual methods. In conclusion, this study underscores the merits of a refined electronic property inventory system. Notably, the research suggests a need for careful consideration of process complexities in outsourcing decisions and showcases the swift, precise, and transparent accounting provided by e-AIMSS deployments, thereby nurturing transparency and public confidence. This innovative approach holds promise for broader application within the realm of e-government processes. (shrink)

RESUMO A alimentação é o fator que mais onera um sistema de produção animal. Assim, a utilização de diferentes estratégias de alimentação dos animais ainda é o grande desafio da nutrição animal, principalmente, levando em consideração as exigências nutricionais de diferentes categorias de ruminantes, em especial bovinos em regiões tropicais, haja vista que a sazonalidade na produção de forragens afeta diretamente a produção bovina, promovendo inadequação no atendimento das exigências nutricionais dos animais principalmente em minerais e vitaminas. Uma alimentação que (...) não atenda as exigências nutricionais dos ruminantes gera prejuízos no sistema de produção, além de, em casos mais graves, ocasionar a perda do animal. Estudos que abordam o efeito e a importância de vitaminas e minerais na nutrição bovina são escassos e necessários. Recentemente a National Research Council (NRC) apresentou novos registros das exigências nutricionais das vitaminas e minerais. Essas alterações proporcionam um impacto econômico significativo em relação à nutrição animal. Nesse sentido, objetivou-se com esta revisão trazer informações acerca de vitaminas e minerais na nutrição de bovinos em pastejo. -/- Palavras-chave: Alimentação animal; forragem; pastagem; requerimentos nutricionais; ruminantes; vitaminas lipossolúveis (Source: AGROVOC). -/- ABSTRACT Animal feed is the factor that most burdens a production system. Thus, the use of different animal feeding strategies is still the great challenge of animal nutrition, taking into account the nutritional requirements of different categories of ruminants, especially cattle in tropical regions, given that seasonality in forage production directly affects cattle production, promoting inadequacy in meeting the nutritional requirements of animals, mainly in minerals and vitamins. A diet that does not meet the nutritional requirements of ruminants generates losses in the production system, in addition to, in more serious cases, causing the loss of the animal. Studies that address the effect and importance of vitamins and minerals in bovine nutrition are scarce and necessary. Recently the National Research Council (NRC) presented new records of the nutritional requirements of vitamins and minerals. These changes provide a significant economic impact on animal nutrition. In this sense, the objective of this review was to bring information about vitamins and minerals in the nutrition of grazing cattle. -/- Keywords: Animal feeding; fat soluble vitamins; forage; nutritional requirements; pasture feeding; ruminants (Source: AGROVOC). -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- 1. Cavalcanti CPL, Silva e Macedo TJ, Gois GC, Menezes VG, Monte APO, Silva AD, Silva DJM, Silva EO, Araújo GGL, Rodrigues RTS, Wischral A, Matos MHT, Queiroz MAA. 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Nutrição Sobre a Reprodução e Fertilidade dos Bovinos. Emanuel Isaque Cordeiro da Silva, 2021. 56. DA SILVA, Emanuel Isaque Cordeiro. Suplementação e formulação de sal mineral e mistura múltipla para bovinos. Revista Universitária Brasileira, v. 2, n. 1, 2024. (shrink)

Wie können Freiheit und Widerstand innerhalb von Foucaults Theorie der Macht und Subjektivierung konzipiert werden? Karsten Schubert liefert die erste systematische Rekonstruktion der sozialphilosophischen Debatte um Freiheit bei Foucault und eine neue Lösung für das Freiheitsproblem: Freiheit als die Fähigkeit zur reflexiven Kritik der eigenen Subjektivierung – kurz: Freiheit als Kritik – ist das Resultat von freiheitlicher Subjektivierung in politischen Institutionen. Der Band zeigt so die Konsequenzen von Foucaults Freiheitsdenken für die Demokratietheorie und die allgemeine sozialphilosophische Freiheitsdiskussion auf.

A choice function C is rational iff: if it allows a path through a sequence of decisions with a particular outcome, then that outcome is amongst the ones that C would have chosen from amongst all the possible outcomes of the sequence. This implies, and it is the strongest definition that implies, that anyone who is irrational could be talked out of their own preferences. It also implies weak but non-vacuous constraints on choices over ends. These do not include alpha (...) or beta. (shrink)

Only our lineage has ever used trackways reading to find unseen and unheard targets. All other terrestrial animals, including our great ape cousins, use scent trails and airborne odors. Because trackways as natural signs have very different properties, they possess an information-rich narrative structure. There is good evidence we began to exploit conspecific trackways in our deep past, at first purely associatively, for safety and orienteering when foraging in vast featureless wetlands. Since our own old trackways were recognizable they were (...) self-mirroring, triggering memories of what we had been up to in the past. Using them to find our way back to the band when temporarily lost or to re-find a resource-rich area discovered the day before enabled optimal foraging. Selection for daily reiteration of one’s own old trackways therefore triggered the evolution of what is distinctive about human cognition: the autobiographical or narrative (episodic) faculty for imaginative self-projection. This faculty enabled us to glean useful social information from the stories “told” by other band members’ old trackways, and created spin-off capacities for fast-track social learning. Resultant increases in socioecological complexity then created positive selective feedback loops for further entrenchment. Incrementally we became the ultra-social narrative-minded ape, capable of creating cumulative culture. (shrink)

A cosmological principle, because it was the first to be created, Exu presents itself as the creative protomatter, whose expansive and unfinished character makes possible the appearanceof all other creations. He is the animating principle of existence and in everything there isExu. The crossroads is its space-time and this fact would explain why “black culture is acrossroads culture”. But, incarnated in Afro-diasporic practices in the Atlantic bands, Exunot only vigorously maintains his multifaceted power, showing that colonial redemption didnot obtain the (...) expected result, but also shows that its everyday meanings in the African BlackDiaspora here in the Americas they are the result of battles, negotiations, authoritarianism,power regimes, violence, transgressions, silencing and alliances experienced in the colonialdynamic, as Luiz Rufno reminds us in his book Pedagogia das Encruzilhadas (2019). (shrink)

Gegen die verbreitete Vorstellung, dass Negativität im Interesse von mehr Selbstverwirklichung, Produktivität und Positivität überwunden oder be-grenzt werden muss, eröffnet dieser Band eine andere Perspektive. Er geht den verschiedenen Formen des Negativen in Kunst, Recht und Politik nach, um zu zeigen, dass es nicht allein eine Negativität gibt, die dem Gelingen im Weg steht oder zu dessen sicher beherrschtem Mittel wird. Die Beiträge des Bandes erweisen Negativität vielmehr als eine Kraft der Befreiung, die ein Gelingen anderer Art ermöglicht.

Geschlecht und Gewalt, das Thema dieses Bandes, betrifft nicht nur die Frage nach den Charakteristika und Ursachen sexueller Aggression, sondern auch die Frage nach angeblichen geschlechtsspezifischen Formen der Aggression. Der vorliegende Beitrag befasst sich mit beidem und diskutiert sie als Teil von begrifflichen Ausweitungen der Kampfzone, d.h. der Erweiterungen des Aggressionsbegriffs im Verlauf der wissenschaftlichen Aggressionsforschung der zweiten Hälfte des 20. Jahrhunderts. Der Beitrag zeigt unter Anderem: was als Aggression wahrgenommen wird und in der Wissenschaft als solche gezählt wird, verändert (...) sich mit der Gesellschaft. Dabei wird aus epistemologischer bzw. wissenschaftsphilosophischer Perspektive gezeigt, wie sich rassistische, Status-, und Geschlechtsstereotype auf begriffliche Entscheidungen in wissenschaftlicher Forschung auswirken und somit die wissenschaftliche Arbeit am Begriff beeinflussen können. (shrink)

The public health crisis is started with emergence of new coronavirus on 11 February 2020 which triggered as coronavirus disease-2019 (COVID-19) pandemics. The causative agent in COVID-19 is made up of positively wrapped single-stranded RNA viruses ~ 30 kb in size. The epidemiology, clinical features, pathophysiology, and mode of transmission have been documented well in many studies, with additional clinical trials are running for several antiviral agents. The spreading potential of COVID-19 is faster than its two previous families, the severe (...) acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). Apart from clinical manifestation, comorbid status is playing key role for prevalence of COVID-19 infection and mortalities. The comorbid effects associated with COVID-19 are diabetes, cardiovascular, digestive, hepatitis-B, cerebrovascular, hypertension, liver injury, coronary heart disease, cancer, rheumatoid arthritis, and neurological impairment. Antimalarial drugs (chloroquine and hydroxychloroquine), remdesivir, Tocilizumab, clopinavir/ritonavir, convalescent plasma therapy, spike protein-angiotensin-converting enzyme 2 (ACE2) inhibitors, human monoclonal antibodies, mRNA-1273, mesenchymal stem cells, Indian and Chinese traditional medicine, small molecules antioxidant, natural products and dietary supplements, high doses of vitamin-E, -C, -D, minerals, flavonoids,and IFN-beta are therapeutic intervention running to develop treatment against COVID-19. Although clinical usage of these therapeutic agents against COVID-19 is well documented, cytokine storms, absence of appropriate animal model have limited its therapeutic use. This review explores the clinical information currently available on COVID-19 on the mechanisms of infection, prevention, management, comorbid status, and current drug treatment options. (shrink)

Is Ethics a rubber band ? Is Ethics a stretching value which goes from selfishness to altruism ?