Results for 'Graeme Nicholson'

43 found
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  1. The Concept of Mechanism in Biology.Daniel J. Nicholson - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):152-163.
    The concept of mechanism in biology has three distinct meanings. It may refer to a philosophical thesis about the nature of life and biology (‘mechanicism’), to the internal workings of a machine-like structure (‘machine mechanism’), or to the causal explanation of a particular phenomenon (‘causal mechanism’). In this paper I trace the conceptual evolution of ‘mechanism’ in the history of biology, and I examine how the three meanings of this term have come to be featured in the philosophy of biology, (...)
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  2. Neither Logical Empiricism nor Vitalism, but Organicism: What the Philosophy of Biology Was.Daniel J. Nicholson & Richard Gawne - 2015 - History and Philosophy of the Life Sciences 37 (4):345-381.
    Philosophy of biology is often said to have emerged in the last third of the twentieth century. Prior to this time, it has been alleged that the only authors who engaged philosophically with the life sciences were either logical empiricists who sought to impose the explanatory ideals of the physical sciences onto biology, or vitalists who invoked mystical agencies in an attempt to ward off the threat of physicochemical reduction. These schools paid little attention to actual biological science, and as (...)
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  3. The Return of the Organism as a Fundamental Explanatory Concept in Biology.Daniel J. Nicholson - 2014 - Philosophy Compass 9 (5):347-359.
    Although it may seem like a truism to assert that biology is the science that studies organisms, during the second half of the twentieth century the organism category disappeared from biological theory. Over the past decade, however, biology has begun to witness the return of the organism as a fundamental explanatory concept. There are three major causes: (a) the realization that the Modern Synthesis does not provide a fully satisfactory understanding of evolution; (b) the growing awareness of the limits of (...)
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  4. Organisms ≠ Machines.Daniel J. Nicholson - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):669-678.
    The machine conception of the organism (MCO) is one of the most pervasive notions in modern biology. However, it has not yet received much attention by philosophers of biology. The MCO has its origins in Cartesian natural philosophy, and it is based on the metaphorical redescription of the organism as a machine. In this paper I argue that although organisms and machines resemble each other in some basic respects, they are actually very different kinds of systems. I submit that the (...)
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  5. The Quantum Complexity behind Quantum Reality.Graeme Robertson - manuscript
    The talk is called ‘The QUANTUM COMPLEXITY behind Quantum Reality’. It is divided into 3 parts: an outline of the essentials of quantum theory, a discussion of some glaring problems of interpretation, and my shocking philosophical conclusions.
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  6. On Being the Right Size, Revisited: The Problem with Engineering Metaphors in Molecular Biology.Daniel J. Nicholson - 2020 - In Sune Holm & Maria Serban (eds.), Philosophical Perspectives on the Engineering Approach in Biology: Living Machines? New York: Routledge. pp. 40-68.
    In 1926, Haldane published an essay titled 'On Being the Right Size' in which he argued that the structure, function, and behavior of an organism are strongly conditioned by the physical forces that exert the greatest impact at the scale at which it exists. This chapter puts Haldane’s insight to work in the context of contemporary cell and molecular biology. Owing to their minuscule size, cells and molecules are subject to very different forces than macroscopic organisms. In a sense, macroscopic (...)
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  7. Biological Atomism and Cell Theory.Daniel J. Nicholson - 2010 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 41 (3):202-211.
    Biological atomism postulates that all life is composed of elementary and indivisible vital units. The activity of a living organism is thus conceived as the result of the activities and interactions of its elementary constituents, each of which individually already exhibits all the attributes proper to life. This paper surveys some of the key episodes in the history of biological atomism, and situates cell theory within this tradition. The atomistic foundations of cell theory are subsequently dissected and discussed, together with (...)
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  8. Rethinking Woodger’s Legacy in the Philosophy of Biology.Daniel J. Nicholson & Richard Gawne - 2014 - Journal of the History of Biology 47 (2):243-292.
    The writings of Joseph Henry Woodger (1894–1981) are often taken to exemplify everything that was wrongheaded, misguided, and just plain wrong with early twentieth-century philosophy of biology. Over the years, commentators have said of Woodger: (a) that he was a fervent logical empiricist who tried to impose the explanatory gold standards of physics onto biology, (b) that his philosophical work was completely disconnected from biological science, (c) that he possessed no scientific or philosophical credentials, and (d) that his work was (...)
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  9. A Manifesto for a Processual Philosophy of Biology.John A. Dupre & Daniel J. Nicholson - 2018 - In Daniel J. Nicholson & John Dupré (eds.), Everything Flows: Towards a Processual Philosophy of Biology. Oxford, United Kingdom: Oxford University Press.
    This chapter argues that scientific and philosophical progress in our understanding of the living world requires that we abandon a metaphysics of things in favour of one centred on processes. We identify three main empirical motivations for adopting a process ontology in biology: metabolic turnover, life cycles, and ecological interdependence. We show how taking a processual stance in the philosophy of biology enables us to ground existing critiques of essentialism, reductionism, and mechanicism, all of which have traditionally been associated with (...)
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  10. The Real Truth About the Unreal Future.Rachael Briggs & Graeme A. Forbes - 2012 - In Karen Bennett & Dean W. Zimmerman (eds.), Oxford Studies in Metaphysics volume 7. Oxford, GB: Oxford University Press.
    Growing-Block theorists hold that past and present things are real, while future things do not yet exist. This generates a puzzle: how can Growing-Block theorists explain the fact that some sentences about the future appear to be true? Briggs and Forbes develop a modal ersatzist framework, on which the concrete actual world is associated with a branching-time structure of ersatz possible worlds. They then show how this branching structure might be used to determine the truth values of future contingents. They (...)
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  11. Everything Flows: Towards a Processual Philosophy of Biology.Daniel J. Nicholson & John Dupré (eds.) - 2018 - Oxford, United Kingdom: Oxford University Press.
    This collection of essays explores the metaphysical thesis that the living world is not made up of substantial particles or things, as has often been assumed, but is rather constituted by processes. The biological domain is organised as an interdependent hierarchy of processes, which are stabilised and actively maintained at different timescales. Even entities that intuitively appear to be paradigms of things, such as organisms, are actually better understood as processes. Unlike previous attempts to articulate processual views of biology, which (...)
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  12. Non-eliminative reductionism: the basis of a science of conscious experience?Dennis Nicholson - forthcoming - Philosophical Psychology.
    A physicalist view of qualia labelled non-eliminative reductionism is outlined. If it is true, qualia and physicalism can co-exist without difficulty. First, qualia present no particular problem for reductionist physicalism - they are entirely physical, can be studied and explained using the standard scientific approach, and present no problem any harder than any other scientists face. Second, reductionist physicalism presents no particular problem for qualia – they can be encompassed within an entirely physicalist position without any necessity, either to reduce (...)
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  13. Is the Cell Really a Machine?Daniel J. Nicholson - 2019 - Journal of Theoretical Biology 477:108–126.
    It has become customary to conceptualize the living cell as an intricate piece of machinery, different to a man-made machine only in terms of its superior complexity. This familiar understanding grounds the conviction that a cell's organization can be explained reductionistically, as well as the idea that its molecular pathways can be construed as deterministic circuits. The machine conception of the cell owes a great deal of its success to the methods traditionally used in molecular biology. However, the recent introduction (...)
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  14. Reconceptualizing the Organism: From Complex Machine to Flowing Stream.Daniel J. Nicholson - 2018 - In Daniel J. Nicholson & John Dupré (eds.), Everything Flows: Towards a Processual Philosophy of Biology. Oxford, United Kingdom: Oxford University Press.
    This chapter draws on insights from non-equilibrium thermodynamics to demonstrate the ontological inadequacy of the machine conception of the organism. The thermodynamic character of living systems underlies the importance of metabolism and calls for the adoption of a processual view, exemplified by the Heraclitean metaphor of the stream of life. This alternative conception is explored in its various historical formulations and the extent to which it captures the nature of living systems is examined. Following this, the chapter considers the metaphysical (...)
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  15. The Machine Conception of the Organism in Development and Evolution: A Critical Analysis.Daniel J. Nicholson - 2014 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 48:162-174.
    This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for conceptualizing living systems, many biologists and philosophers continue to draw upon the MCO or tacitly accept it as the standard model of the organism. This paper analyses the specific difficulties that arise when the MCO is invoked in the study of development and evolution. In (...)
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  16. Towards a scientific account of experience.Dennis Nicholson - manuscript
    I outline and develop a particular physicalist perspective on qualia, and suggest that it may be the basis of a correct account of the relationship of mental states to the physical world. Assume that a quale is a perspective on a physical state in the organism – the reality as known as distinct from the reality as such – but that the perspective, though it entails irreducible experiential knowledge, has no physical substance over that encompassed in the physical state itself. (...)
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  17. Philosophical Problems of Quantum Ontology.Graeme Donald Robertson - 1976 - Dissertation, Cambridge
    What is a physical object according to the theory of quantum mechanics? The first answer to be considered is that given by Bohr in terms of the concept of complementarity. This interpretation is illustrated by way of an example, the two slit experiment, which highlights some of the associated problems of ontology. One such problem is the so-called problem of measurement or observation. Various interpretations of measurement in Quantum Theory, including those of Heisenberg, von Neumann, Everett and Bohr, are compared (...)
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  18. Unity Consciousness and the Perfect Observer: Quantum Understanding beyond Reason and Reality.Graeme Robertson - 1995 - Basingstoke: ROBERTSON (Publishing).
    This book has been written for eighteen year olds (or anyone who will listen) as an honest attempt to face their justified questionings and to offer them a metaphysical framework with which to confront the twenty-first century. It is vitally important that certain modes of thought are uprooted and new modes put in their place if mankind and planet Earth are not soon to suffer an historic global catastrophe. Apart from the continuing world-wide proliferation of conventional, chemical, biological and nuclear (...)
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  19. Clarifying how to deploy the public interest criterion in consent waivers for health data and tissue research.G. Owen Schaefer, Graeme Laurie, Sumytra Menon, Alastair V. Campbell & Teck Chuan Voo - 2020 - BMC Medical Ethics 21 (1):1-10.
    Background Several jurisdictions, including Singapore, Australia, New Zealand and most recently Ireland, have a public interest or public good criterion for granting waivers of consent in biomedical research using secondary health data or tissue. However, the concept of the public interest is not well defined in this context, which creates difficulties for institutions, institutional review boards and regulators trying to implement the criterion. Main text This paper clarifies how the public interest criterion can be defensibly deployed. We first explain the (...)
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  20. Non-eliminative Reductionism: Reconciling Qualia and Physicalism.Dennis Nicholson - manuscript
    A physicalist view of qualia labelled non-eliminative reductionism is outlined. If it is true, qualia and physicalism can co-exist without difficulty. First, qualia present no particular problem for reductionist physicalism - they are entirely physical, can be studied and explained using the standard scientific approach, and present no problem any harder than any other scientists face. Second, reductionist physicalism presents no particular problem for qualia – they can be encompassed within an entirely physicalist position without any necessity, either to reduce (...)
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  21. On Nature and Normativity: Normativity, Teleology, and Mechanism in Biological Explanation.Lenny Moss & Daniel J. Nicholson - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):88-91.
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  22. The future, and what might have been.R. A. Briggs & Graeme A. Forbes - 2019 - Philosophical Studies 176 (2):505-532.
    We show that five important elements of the ‘nomological package’— laws, counterfactuals, chances, dispositions, and counterfactuals—needn’t be a problem for the Growing-Block view. We begin with the framework given in Briggs and Forbes (in The real truth about the unreal future. Oxford studies in metaphysics. Oxford University Press, Oxford, 2012 ), and, taking laws as primitive, we show that the Growing-Block view has the resources to provide an account of possibility, and a natural semantics for non-backtracking causal counterfactuals. We show (...)
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  23. The Idea of Infinity in its Physical and Spiritual Meanings.Graham Nicholson - manuscript
    Abstract -/- The concept of infinity is of ancient origins and has puzzled deep thinkers ever since up to the present day. Infinity remains somewhat of a mystery in a physical world in which our comprehension is largely framed around the concept of boundaries. This is partly because we live in a physical world that is governed by certain dimensions or limits – width, breadth, depth, mass, space, age and time. To our ordinary understanding, it is a seemingly finite world (...)
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  24. Proclus Commentary on Plato's Republic volume 2.Dirk Baltzly, Graeme Miles & John Finamore - 2022 - Cambridge: CUP.
    The commentary on Plato's Republic by Proclus (d. 485 CE), which takes the form of a series of essays, is the only sustained treatment of the dialogue to survive from antiquity. This three-volume edition presents the first complete English translation of Proclus' text, together with a general introduction that argues for the unity of Proclus' Commentary and orients the reader to the use which the Neoplatonists made of Plato's Republic in their educational program. Each volume is completed by a Greek (...)
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  25. Does the new route reach its destination?Teresa Robertson & Graeme Forbes - 2006 - Mind 115 (458):367-374.
    A New Route to the Necessity of Origin’, Guy Rohrbaugh and Louis deRossett argue for the Necessity of Origin in a way that they believe avoids use of any kind of transworld constitutional sufficiency principle. In this discussion, we respond that either their arguments do imply a sufficiency principle, or else they entirely fail to establish the Necessity of Origin.
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  26. Proclus: Commentary on Plato's Republic, vol 1.Dirk Baltzly, Graeme Miles & John Finamore - 2018 - Cambridge: CUP.
    Covers Essays 1 to 6 in Proclus' Commentary and includes a general introduction to the work as a whole.
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  27. Knowledge of Life. [REVIEW]Daniel J. Nicholson - 2014 - Annals of Science 71 (3):434-437.
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  28. An Ethics Framework for Big Data in Health and Research.Vicki Xafis, G. Owen Schaefer, Markus K. Labude, Iain Brassington, Angela Ballantyne, Hannah Yeefen Lim, Wendy Lipworth, Tamra Lysaght, Cameron Stewart, Shirley Sun, Graeme T. Laurie & E. Shyong Tai - 2019 - Asian Bioethics Review 11 (3):227-254.
    Ethical decision-making frameworks assist in identifying the issues at stake in a particular setting and thinking through, in a methodical manner, the ethical issues that require consideration as well as the values that need to be considered and promoted. Decisions made about the use, sharing, and re-use of big data are complex and laden with values. This paper sets out an Ethics Framework for Big Data in Health and Research developed by a working group convened by the Science, Health and (...)
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  29. Multiple Regression Is Not Multiple Regressions: The Meaning of Multiple Regression and the Non-Problem of Collinearity.Michael B. Morrissey & Graeme D. Ruxton - 2018 - Philosophy, Theory, and Practice in Biology 10 (3).
    Simple regression (regression analysis with a single explanatory variable), and multiple regression (regression models with multiple explanatory variables), typically correspond to very different biological questions. The former use regression lines to describe univariate associations. The latter describe the partial, or direct, effects of multiple variables, conditioned on one another. We suspect that the superficial similarity of simple and multiple regression leads to confusion in their interpretation. A clear understanding of these methods is essential, as they underlie a large range of (...)
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  30. Societal-Level Versus Individual-Level Predictions of Ethical Behavior: A 48-Society Study of Collectivism and Individualism.David A. Ralston, Carolyn P. Egri, Olivier Furrer, Min-Hsun Kuo, Yongjuan Li, Florian Wangenheim, Marina Dabic, Irina Naoumova, Katsuhiko Shimizu, María Teresa Garza Carranza, Ping Ping Fu, Vojko V. Potocan, Andre Pekerti, Tomasz Lenartowicz, Narasimhan Srinivasan, Tania Casado, Ana Maria Rossi, Erna Szabo, Arif Butt, Ian Palmer, Prem Ramburuth, David M. Brock, Jane Terpstra-Tong, Ilya Grison, Emmanuelle Reynaud, Malika Richards, Philip Hallinger, Francisco B. Castro, Jaime Ruiz-Gutiérrez, Laurie Milton, Mahfooz Ansari, Arunas Starkus, Audra Mockaitis, Tevfik Dalgic, Fidel León-Darder, Hung Vu Thanh, Yong-lin Moon, Mario Molteni, Yongqing Fang, Jose Pla-Barber, Ruth Alas, Isabelle Maignan, Jorge C. Jesuino, Chay-Hoon Lee, Joel D. Nicholson, Ho-Beng Chia, Wade Danis, Ajantha S. Dharmasiri & Mark Weber - 2014 - Journal of Business Ethics 122 (2):283–306.
    Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...)
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  31. Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project.Chris F. Taylor, Dawn Field, Susanna-Assunta Sansone, Jan Aerts, Rolf Apweiler, Michael Ashburner, Catherine A. Ball, Pierre-Alain Binz, Molly Bogue, Tim Booth, Alvis Brazma, Ryan R. Brinkman, Adam Michael Clark, Eric W. Deutsch, Oliver Fiehn, Jennifer Fostel, Peter Ghazal, Frank Gibson, Tanya Gray, Graeme Grimes, John M. Hancock, Nigel W. Hardy, Henning Hermjakob, Randall K. Julian, Matthew Kane, Carsten Kettner, Christopher Kinsinger, Eugene Kolker, Martin Kuiper, Nicolas Le Novere, Jim Leebens-Mack, Suzanna E. Lewis, Phillip Lord, Ann-Marie Mallon, Nishanth Marthandan, Hiroshi Masuya, Ruth McNally, Alexander Mehrle, Norman Morrison, Sandra Orchard, John Quackenbush, James M. Reecy, Donald G. Robertson, Philippe Rocca-Serra, Henry Rodriguez, Heiko Rosenfelder, Javier Santoyo-Lopez, Richard H. Scheuermann, Daniel Schober, Barry Smith & Jason Snape - 2008 - Nature Biotechnology 26 (8):889-896.
    Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...)
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  32. Review of Graeme Laurie, Genetic Privacy. [REVIEW]Donna Dickenson - 2003 - Journal of Medical Ethics 29:271-374.
    Review of Graeme Laurie, Genetic Privacy: A Challenge to Medico-Legal Norms.
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  33. Stathis Arapostathis and Graeme Gooday, Patently Contestable: Electrical Technologies and Inventor Identities on Trial in Britain. [REVIEW]Sean F. Johnston - 2015 - Technology and Culture 56:276-277.
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  34. The Production of Space.Henri Lefebvre - 1991 - Cambridge, Mass., USA: Wiley-Blackwell.
    Henri Lefebvre has considerable claims to be the greatest living philosopher. His work spans some sixty years and includes original work on a diverse range of subjects, from dialectical materialism to architecture, urbanism and the experience of everyday life. The Production of Space is his major philosophical work and its translation has been long awaited by scholars in many different fields. The book is a search for a reconciliation between mental space and real space. In the course of his exploration, (...)
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  35. Are Salmon's 'Guises' Disguised Fregean Senses?João Branquinho - 1990 - Analysis 50 (1):19 - 24.
    In a review of Frege's Puzzle1, Graeme Forbes makes the claim that Salmon's account of belief might be seen, under certain conditions, as a mere notational variant of a neo-Fregean theory; and thus that such an account might be reduced to a neo-Fregean one simply by rewriting it in terms of Fregean terminology. With a view to supporting his claim, Forbes offers an outline of an account of belief which, according to him, would satisfy the following conditions: (i) it (...)
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  36. Open future, supervaluationism and the growing-block theory: a stage-theoretical account.Roberto Loss - 2021 - Synthese 199 (5-6):14249-14266.
    I present a ‘stage-theoretical’ interpretation of the supervaluationist semantics for the growing-block theory of time according to which the ‘nodes’ on the branching tree of historical possibilities are taken to be possible stages of the growth of the growing-block. As I will argue, the resulting interpretation (i) is very intuitive, (ii) can easily ward off an objection to supervaluationist treatments of the growing-block theory presented by Fabrice Correia and Sven Rosenkranz, and (iii) is also not saddled by the problems affecting (...)
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  37. Genetic privacy: a challenge to medico-legal norms: G Laurie. Cambridge University Press, 2002, 50.00 (hbk), pp 335. ISBN 0521660270. [REVIEW]D. Dickenson - 2003 - Journal of Medical Ethics 29 (6):373-374.
    Review of Graeme Laurie, Genetic Privacy.
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  38. Possibilities and the arguments for origin essentialism.Teresa Robertson - 1998 - Mind 107 (428):729-750.
    In this paper, I examine the case that has been made for origin essentialism and find it wanting. I focus on the arguments of Nathan Salmon and Graeme Forbes. Like most origin essentialists, Salmon and Forbes have been concerned to respect the intuition that slight variation in the origin of an artifact or organism is possible. But, I argue, both of their arguments fail to respect this intuition. Salmon's argument depends on a sufficiency principle for cross-world identity, which should (...)
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  39. Second-Order Arguments, or Do We Still Need Tolerance in the Public Sphere?Aleksei Loginov - 2019 - Changing Societies and Personalities 3 (4):319-332.
    A number of widely discussed court decisions on cases of insults against religious feelings in Russia, such as the relatively recent “Pokemon Go” case of blogger Ruslan Sokolovsky or the lawsuit filed against an Orthodox priest by Nikolai Ryabchevsky in Yekaterinburg for comparing Lenin with Hitler, make pertinent the question of why toleration becomes so difficult in matters concerning religion. In this paper, I revise the classical liberal concept of toleration (David Heyd, Peter Nicholson, and John Horton), arguing that (...)
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  40. Conflict, socialism, and democracy in Mill.Gustavo H. Dalaqua - 2019 - Télos 22 (1-2):33-59.
    Mill’s socialism and democratic theory have led some scholars to accuse him of trying to eliminate conflict from political life. Whereas Graeme Duncan has averred that Mill’s socialism aims to institute a completely harmonious society, James Fitzjames Stephen has contended that Millian democracy sought to evacuate conflict from political discussion. This article reconstructs both critiques and argues they are imprecise. Even if disputes motivated by redistribution of material goods would no longer exist in an egalitarian society, conflicts driven by (...)
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  41. So-labeled neo-fregeanism.Mark Crimmins - 1993 - Philosophical Studies 69 (2-3):265 - 279.
    I explain and criticize a theory of beliefs and of belief sentences offered by Graeme Forbes. My main criticism will be directed at Forbes' idea that, as a matter of the semantic rules of belief reporting -- as a matter of the meaning of belief ascriptions -- to get at the subject's way of thinking in an attitude ascription, we must use expressions that are "linguistic counterparts" of the subject's expressions. I think we often do something like that, but (...)
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  42. Support for Full Disclosure Up Front.Felicitas Holzer & Ignacio Mastroleo - 2015 - Hastings Center Report 45 (1):3-3.
    A commentary on “Models of Consent to Return of Incidental Findings in Genomic Research,” by Paul S. Appelbaum, Erik Parens, Cameron R. Waldman, Robert Klitzman, Abby Fyer, Josue Martinez, W. Nicholson Price II, and Wendy K. Chung, in the July‐August 2014 issue.
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  43. Görkəmli elm və din tədqiqatçısı İan Barbur haqqında, Elm qəzeti, Bakı, AMEA, 2020, №22 (1257), səh.7.Aladdin Malikov - 2020 - Elm Qəzeti 22 (1257):7.
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