"This volume emerged from workshops held at Pennsylvania State University in 2003 and Stanford University in 2005"--P. vii.

In this paper we present applications of the ACGT Master Ontology (MO) which is a new terminology resource for a transnational network providing data exchange in oncology, emphasizing the integration of both clinical and molecular data. The development of a new ontology was necessary due to problems with existing biomedical ontologies in oncology. The ACGT MO is a test case for the application of best practices in ontology development. This paper provides an overview of the application of the ontology within (...) the ACGT project thus far. (shrink)

Numerous research groups are now utilizing Basic Formal Ontology as an upper-level framework to assist in the organization and integration of biomedical information. This paper provides elucidation of the three existing BFO subcategories of realizable entity, namely function, role, and disposition. It proposes one further sub-category of tendency, and considers the merits of recognizing two sub-categories of function for domain ontologies, namely, artifactual and biological function. The motivation is to help advance the coherent ontological treatment of functions, roles, and dispositions, (...) to help provide the potential for more detailed classification, and to shed light on BFO’s general make-up and use. (shrink)

As part of a series of workshops on different aspects of biomedical ontology sponsored by the National Center for Biomedical Ontology (NCBO), a workshop titled "Ontologies of Cellular Networks" took place in Newark, New Jersey, on 27 to 28 March 2008. This workshop included more than 30 participants from various backgrounds in biomedicine and bioinformatics. The goal of the workshop was to provide an introduction to the basic tools and methods of ontology, as well as to (...) enhance coordination between groups already working on ontologies of cellular networks. The meeting focused on three questions: What is an ontology? What is a pathway? What is a cellular network? (shrink)

Introduction to 'Skyrmsfest: Papers in Honor of Brian Skyrms' issue of Philosophical Studies, January 2010. Remarks about Brian Skyrms and about the 10 papers in the issue.

The integration of robotics in the education was one of the aspirations of the K-12 institution in the Philippines. The RoboTeach Extension Project was established to address the challenges associated with the implementation of robotics in K-12 education. This study explores the teachers’ perception of the efficacy in the implementation of the project which focused on training the Department of Education (DepEd) teachers in San Pablo City Laguna, Philippines on the basic concepts and applications of robotics and automation. The (...) topics and learning activities covered during the ten-day training were based on the self-assessment survey results on the level of knowledge of teachers. The study used a descriptive method of research using a quantitative approach and adopted the LSPU Extension Services Evaluation Survey Questionnaire to determine the respondents’ perception of the level of project efficacy. The data were obtained from twenty-five DepEd teachers and analyzed using descriptive statistics such as frequency count, per cent, weighted mean and ANOVA. The respondents were highly satisfied with meeting expectations to attain objectives, training and workshop contents, learning activities, methodologies, instructional materials used, resource person and trainers, training management team, and training management team and training facilities and services. Further, there was no significant difference among their level of satisfaction from day 1 to 5 of the training sessions. Respondents viewed the training as very successful, as evident from the consultation and culminating activity. Thus, the sustainability on the implementation of the project was highly recommended. (shrink)

This paper by Theodore de Laguna presents and argues for the deflationary theory of truth. The paper was first published in French in 1922. The version published here is the original, English version of the paper and has been edited by Joel Katzav.

In this chapter, Grace Andrus de Laguna and Theodore de Laguna critically examine the pragmatist theory of knowledge and offer their own alternative to it.

Some of the barriers to the realisation of equality reflect the value of respecting prerogatives people have to favour themselves. Even G.A. Cohen, whose egalitarianism is especially pervasive and demanding, says that.

In this article, Grace Andrus de Laguna develops a view of human freedom, one according to which it is made possible by the uniqueness of human individuals and the cultural worlds in which they live.

In recent decades, the intertwining ideas of self-determination and well-being have received tremendous support in bioethics. Discussions regarding self-determination, or autonomy, often focus on two dimensions—the capacity of the patient and the freedom from external coercion. The practice of obtaining informed consent, for example, has become a standard procedure in therapeutic and research medicine. On the surface, it appears that patients now have more opportunities to exercise their self-determination than ever. Nonetheless, discussions of patient autonomy in the bioethics literature, which (...) focus on individual patients making particular decisions, neglect the social structure within which health-care decisions are made. Looking through the lens of disability and informed by the feminist conception of relational autonomy, this essay argues that the issue of autonomy is much more complex than the individualist model suggests. The social system and the ableist ideology impose various forms of pressure or oppressive power that can affect people’s ability to choose according to their value system. Even if such powers are not directly coercive, they influence potential parents’ decisions indirectly—they structure their alternatives in such a way that certain options are never considered as viable and other decisions must be made. This paper argues that, instead of only focusing on the individual act of decision-making, we need to pay attention to the social structure that frames people’s decision. (shrink)

The distinction between doing and allowing appears to have moral significance, but the very nature of the distinction is as yet unclear. Philippa Foot's ‘pre-existing threats’ account of the doing/allowing distinction is highly influential. According to the best version of Foot's account an agent brings about an outcome if and only if his behaviour is part of the sequence leading to that outcome. When understood in this way, Foot's account escapes objections by Warren Quinn and Jonathan Bennett. However, more analysis (...) is required to show what makes a relevant condition part of a sequence. Foot's account is promising, but incomplete. (shrink)

Hud Hudson has argued that if MaxCon, Ned Markosian's favored answer to the Simple Question, is true, then there couldn't be gunky objects. If Hudson's argument succeeds, then those who believe that gunky objects are possible have a good reason to reject MaxCon. However, I show that Hudson's argument relies on substantive metaphysical claims that a proponent of MaxCon need not accept. Thus, one who endorses MaxCon need not reject the possibility of gunky objects and those who believe that gunky (...) objects are possible need not reject MaxCon. (shrink)

A broad overview of the NeoKantian movement in Germany, written as an introduction to a series of essays about that movement. -/- .

This paper uses a partially ordered set of syntactic categories to accommodate optionality and licensing in natural language syntax. A complex but well-studied data set pertaining to the syntax of quantifier scope and negative polarity licensing in Hungarian is used to illustrate the proposal. The presentation is geared towards both linguists and logicians. The paper highlights that the main ideas can be implemented in different grammar formalisms, and discusses in detail an implementation where the partial ordering on categories is given (...) by the derivability relation of a calculus with residuated and Galois-connected unary operators. (shrink)

This article defends the principle of sufficient reason (PSR) from a simple and direct valid argument according to which PSR implies that there is a truth that explains every truth, namely an omni-explainer. Many proponents of PSR may be willing to bite the bullet and maintain that, if PSR is true, then there is an omni-explainer. I object to this strategy by defending the principle that explanation is irreflexive. Then I argue that proponents of PSR can resist the conclusion that (...) there is an omni-explainer by denying that explanation distributes over conjunction. In the final section, I consider a plausible revision of this assumption. I argue there that, given the revised assumption, PSR seems to yield a striking picture of the explanatory structure of the universe. I explain why the resulting model does not appear utterly implausible to me. (shrink)

As part of the development of an epistemology for mathematics, some Platonists have defended the view that we have (i) intuition that certain mathematical principles hold, and (ii) intuition of the properties of some mathematical objects. In this paper, I discuss some difficulties that this view faces to accommodate some salient features of mathematical practice. I then offer an alternative, agnostic nominalist proposal in which, despite the role played by mathematical intuition, these difficulties do not emerge.

This paper addresses ways of arguing fors ome form of economic democracy from within a broadly Rawlsian framework. Firstly, one can argue that a right to participate in economic decision-making should be added to the Rawlsian list of basic liberties, protected by the first principle of justice. Secondly,I argue that a society which institutes forms of economic democracy will be more likely to preserve a stable and just basic structure over time, by virtue of the effects of economic democratization on (...) the development of an active, democratic character among citizens. Thirdly, I argue that a proper understanding of the demands of the difference principle shows that justice demands more than ex post redistribution, but also requires the ex ante redistribution of power and authority in economic life. This connects to Rawls’s discussion of the badness of inequality, and to his endorsement of a “property-owning democracy”. -/- My conclusion is that, even if we may doubt the success of this first Rawlsian argument,the second and third arguments are both successful, and together establish a strong Rawlsian case forseeing economic democratization as a requirement of justice. (shrink)

In "Evil and the Justice of God", N.T. Wright presses the point that attempting to solve the philosophical problem of evil is an immature response to the existence of evil--a response that belittles the real problem of evil, which is just the fact that evil is bad and needs to be dealt with. As you might expect, I am not inclined to endorse this sort of sweeping indictment of the entire field of research on the philosophical problem of evil. (I (...) sort of doubt that Wright really meant to either.) But I do think that there is a kernel of truth in what I take to be Wright's fundamental objection to attempts to solve the philosophical problem of evil. In the first section of what follows, I will try briefly to explain why. I will then go on to argue that, despite this fact, certain efforts at solving the problem of evil avoid Wright's objection. Indeed, drawing on recent work by Elenore Stump, I will argue that one perfectly legitimate way to try to solve the philosophical problem of evil is to follow precisely what seems to be the main piece of advice in "Evil and the Justice of God": namely, to look more seriously than we have at the attitudes taken toward evil by human authors of and characters in the Bible, and to attend more carefully to what the Bible says about how God deals with evil. (shrink)

¿De qué hablamos cuando decimos Diseño Sustentable? El diseño sustentable podría definirse como el diseño que tiene en cuenta los aspectos ambientales en todos los niveles de producción. Así mismo, persigue el objetivo de fabricar productos que aporten el menor impacto posible en el ecosistema a lo largo de todo el ciclo de vida. Es muy difícil encontrar productos de consumo que cumplan puntualmente con los Preceptos del eco diseño y que sean exitosos en el mercado. Ante esta situación es (...) necesario revisar los aspectos involucrados en la concepción de un nuevo producto: ¿El rol del diseñador es el adecuado?, ¿Existe una seria y responsable conciencia por parte de los empresarios para llevar adelante un proyecto de eco diseño?, ¿Son los productos eco lo suficientemente atractivos para captar la atención de los consumidores? (shrink)

The notions of types of dialogue and dialectical relevance are central themes in Walton’s work and the grounds for a dialectical approach to many fallacies. After outlining the dialogue models constituting the background of Walton’s account, this article presents the concepts of dialectical relevance and dialogue shifts in their application to biased argumentation, fallacious moves, and illicit argumentative strategies. Showing the different dialectical proposals Walton advanced in several studies on argumentation as a development of a dialogical system, it has proved (...) possible to highlight the fundamental aspects of his theory in a comprehensive model of communication and interaction. (shrink)

Intersectionality has become the primary analytic tool that feminist and anti-racist scholars deploy for theorizing identity and oppression. This paper exposes and critically interrogates the assumptions underpinning intersectionality by focusing on four tensions within intersectionality scholarship: the lack of a defined intersectional methodology; the use of black women as quintessential intersectional subjects; the vague definition of intersectionality; and the empirical validity of intersectionality. Ultimately, my project does not seek to undermine intersectionality; instead, I encourage both feminist and anti-racist scholars to (...) grapple with intersectionality's theoretical, political, and methodological murkiness to construct a more complex way of theorizing identity and oppression. (shrink)

We lay out the fatalist’s argument, making sure to clarify which dialectical moves are available to the libertarian. We then offer a more robust presentation of Ockhamism, responding to obvious objections and teasing out the implications of the view. At this point, we discuss presentism and eternalism in more detail. We then present our argument for the claim that the libertarian cannot take Ockham’s way out of the fatalism argument unless she rejects presentism. Finally, we consider and dispense with objections (...) to our argument. In the end, it ought to be clear that the libertarian must make a choice between Ockham’s way out and presentism. (shrink)

One determining characteristic of contemporary sociopolitical systems is their power over increasingly large and diverse populations. This raises questions about power relations between heterogeneous individuals and increasingly dominant and homogenizing system objectives. This article crosses epistemic boundaries by integrating computer engineering and a historicalphilosophical approach making the general organization of individuals within large-scale systems and corresponding individual homogenization intelligible. From a versatile archeological-genealogical perspective, an analysis of computer and social architectures is conducted that reinterprets Foucault’s disciplines and political anatomy to (...) establish the notion of politics for a purely technical system. This permits an understanding of system organization as modern technology with application to technical and social systems alike. Connecting to Heidegger’s notions of the enframing (Gestell) and a more primal truth (anfänglicheren Wahrheit), the recognition of politics in differently developing systems then challenges the immutability of contemporary organization. Following this critique of modernity and within the conceptualization of system organization, Derrida’s democracy to come (à venir) is then reformulated more abstractly as organizations to come. Through the integration of the discussed concepts, the framework of Large-Scale Systems Composed of Homogeneous Individuals (LSSCHI) is proposed, problematizing the relationships between individuals, structure, activity, and power within large-scale systems. The LSSCHI framework highlights the conflict of homogenizing system-level objectives and individual heterogeneity, and outlines power relations and mechanisms of control shared across different social and technical systems. (shrink)

Charles Peirce famously divided all signs into icons, indices and symbols. The past few decades have seen mainstream analytic philosophy broaden its traditional focus on symbols to recognise the so-called essential indexical. Can the moral now be extended to icons? Is there an “essential icon”? And if so, what exactly would be essential about it? It is argued that there is and it consists in logical form. Danielle Macbeth’s radical new “expressivist” interpretation of Frege’s logic and Charles Peirce’s existential graphs (...) are mobilized in support of this claim. (shrink)

Ontology is the philosophical discipline which aims to understand how things in the world are divided into categories and how these categories are related together. This is exactly what information scientists aim for in creating structured, automated representations, called 'ontologies,' for managing information in fields such as science, government, industry, and healthcare. Currently, these systems are designed in a variety of different ways, so they cannot share data with one another. They are often idiosyncratically structured, accessible only to those who (...) created them, and unable to serve as inputs for automated reasoning. This volume shows, in a nontechnical way and using examples from medicine and biology, how the rigorous application of theories and insights from philosophical ontology can improve the ontologies upon which information management depends. (shrink)

De re or singular thoughts are, intuitively, those essentially or constitutively about a particular object or objects; any thought about different objects would be a different thought. How should a philosophical articulation or thematization of their nature look like? In spite of extended discussion of the issue since it was brought to the attention of the philosophical community in the late fifties by Quine (1956), we are far from having a plausible response. Discussing the matter in connection with the status (...) of the Kripkean category of the contingent a priori, Donnellan (1979) argued that what can be properly classified as knowable a priori about utterances like those involving ‘one meter’ or ‘Neptune’ famously proposed by Kripke (1980) cannot be the very same singular content that is contingent he distinguished to that end between knowing a true proposition expressed by an utterance, and knowing that an utterance expresses a true proposition. Evans (1979) replied that, for a very specific sort of cases involving “descriptive names”, a related proto-two-dimensionalist account should be preferred, on which it is not the singular contingent content, but rather a general descriptive one which is knowable a priori. In a series of papers, Robin Jeshion (2000, 2001) has recently attacked Donnellan's proposal, arguing in favour of the most straightforward interpretation of Kripke's claim: in the relevant cases, the very same singular content can be both contingent and knowable a priori. This paper appeals to a generalized version of two-dimensional semantics to advance an account of the Kripkean cases along the lines of Evans's, and argues that Jeshion's compelling arguments against Donnellan's view do not apply to this version. (shrink)

One interesting aspect of the Hwang-case has been the way in which this affair was assessed by academic journals such as Nature. Initially, Hwang’s success was regarded as evidence for the detrimental effects of research ethics, slowing down the pace of research in Western countries. Eventually, however, Hwang’s debacle was seen as evidence for the importance of ethics in the life sciences. Ironically, it was concluded that the West maintains its prominence in science (as a global endeavour) precisely because it (...) has its ethics in place. Bioethics was now seen as an indispensable part of quality control. In this article, I will claim that the Hwang case rather reveals that there is no reason for complacency and that there are substantial challenges awaiting us. They have to do with major transformations in the way knowledge is produced and research in the life sciences is conducted (such as the increase in pace and scale, globalisation and the growing importance of ICT and bioinformation). These transformations call for a different kind of bioethics. The focus must shift from duties of autonomous researchers concerning visible research subjects (“micro-ethics”) to responsibilities of institutionalised research networks in managing and processing large amounts of bioinformation (“macro-ethics”). Concepts such as transparency, reliability and benefit-sharing will become more important than concepts such as informed consent. Basically, it is a resurgence of the tension between the Kantian and the Hegelian view of ethics. The contours of macro-ethics will be elaborated notably as it is emerging in bioethical debates over biobanking and genetic databanks. (shrink)

The purpose of this paper is to inquire into the relationship between persuasive definition and common knowledge (propositions generally accepted and not subject to dispute in a discussion). We interpret the gap between common knowledge and persuasive definition (PD) in terms of potential disagreements: PDs are conceived as implicit arguments to win a potential conflict. Persuasive definitions are analyzed as arguments instantiating two argumentation schemes, argument from classification and argument from values, and presupposing a potential disagreement. The argumentative structure of (...) PDs reveals different levels of disagreement, and different pos-sibilities of resolving the conflict or causing dialogical deadlock. (shrink)

This paper argues that the relevant unit of analysis for assessing the justice of an immigration policy is the socially-situated individual (as opposed to the individual simpliciter or the nation-state, for example). This methodological principle is demonstrated indirectly by showing how some liberal, cosmopolitan defenses of "open borders" and the alleged right of immigration fail by their own standards, owing to the implicit adoption of an inappropriate unit of analysis.

In this article we explore an argumentative pattern that provides a normative justification for expected utility functions grounded on empirical evidence, showing how it worked in three different episodes of their development. The argument claims that we should prudentially maximize our expected utility since this is the criterion effectively applied by those who are considered wisest in making risky choices (be it gamblers or businessmen). Yet, to justify the adoption of this rule, it should be proven that this is empirically (...) true: i.e. that a given function allows us to predict the choices of that particular class of agents. We show how expected utility functions were introduced and contested in accordance with this pattern in the 18th century and how it recurred in the 1950s when Allais made his case against the neo-Bernoullians. (shrink)

In this paper, I'll present a general way of "reading off" introduction/elimination rules from elimination/introduction rules, and define notions of harmony and stability on the basis of it.

En el año 2000 se publica la quinta revisión de la Declaración de Helsinki con el objetivo de responder a nuevos problemas éticos producidos en la última década por las investigaciones biomédicas realizadas en países en desarrollo. Una de las innovaciones más importantes que presenta la Declaración es la formulación del principio ético de acceso post investigación obligatorio para los participantes. En el presente trabajo, comienzo con la exposición del estado del consenso internacional sobre el carácter obligatorio del acceso post (...) investigación, de acuerdo con las guías y documentos de países desarrollados y en desarrollo. Luego, reconstruyo la justificación ética del principio de acceso post investigación y discuto algunos argumentos que se han presentado en su contra. De esta forma, defiendo la idea de que el acceso post investigación a las intervenciones probadas efectivas debe ser obligatorio siempre que los participantes se beneficien de las mismas y no tengan un acceso alternativo a ellas. (shrink)

A comparison of disjunctive theories of action and perception. The development of a theory of action that warrants the name, a disjunctive theory. On this theory, there is an exclusive disjunction: either an action or an event (in one sense). It follows that in that sense basic actions do not have events intrinsic to them.

EN In his “Logic, Language, and Knowledge” Chateaubriand denounces the tyranny of belief , but takes some positions on knowledge and justification which seem to be too exacting. The fact that Chateaubriand derives constraints on the notion of justification by a close parallel to the notion of proof makes it unnecessarily loaded with the individual, rather than with the collective perspective. His position seems to leave little room for common knowledge, collective knowledge and usual common-sense knowledge, and absolutely no room (...) for explaining how people take correct decisions based on apparently faulty notions of knowledge and justification. -/- PT Em “Logic, Language, and Knowledge” Chateaubriand denuncia a tirania da crença , mas toma posições sobre conhecimento e justificação que parecem demasiado exigentes. O fato de Chateaubriand derivar condições sobre a noção de justificação a partir de uma estreita analogia com a noção de prova torna a noção de justiticação desnecessariamente carregada com a perspectiva indivídual, em detrimento da perspectiva coletiva. Sua posição parece deixar pouco espaço para noções como conhecimento comum, conhecimento coletivo e senso comum, e absolutamente nenhum espaço para explicar como as pessoas tomam decisões corretas com base em noções aparentemente errôneas de conhecimento e de justificação. (shrink)

Des branches entières des mathématiques sont fondées sur des liens posés entre les nombres et l’espace : mesure de longueurs, définition de repères et de coordonnées, projection des nombres complexes sur le plan… Si les nombres complexes, comme l’utilisation de repères, sont apparus relativement récemment (vers le XVIIe siècle), la mesure des longueurs est en revanche un procédé très ancien, qui remonte au moins au 3e ou 4e millénaire av. J-C. Loin d’être fortuits, ces liens entre les nombres et l’espace (...) reflèteraient une intuition fondamentale, universelle, façonnée au cours des millénaires par la sélection naturelle, et qui aurait servi de guide et d’inspiration aux mathématiciens au fil des siècles. (shrink)

The traditional way of drawing the a priori/a posteriori distinction, bequeathed to us by Kant, leads to overestimating the role that experience plays in justifying ourbeliefs. There is an irony in this: though Kant was in the rationalist camp, his way of drawing the distinction gives an unfair advantage to radical empiricism. I offer an alternative way of drawing the distinction, one that does not bias the rationalist/empiricist debate.

dynamic ontologies must be inferred and populated in part from the reference corpora themselves, but ontological rela-.

Summary We offer a novel historical-philosophical framework for discussing experimental practice which we call ‘Generating Experimental Knowledge’. It combines three different perspectives: experimental systems, concept formation, and the pivotal role of error. We then present an historical account of the invention of the Scanning Tunnelling Microscope (STM), or Raster-Tunnelmikroskop, and interpret it within the proposed framework. We show that at the outset of the STM project, Binnig and Rohrer—the inventors of the machine—filed two patent disclosures; the first is dated 22 (...) December 1978 (Switzerland), and the second, two years later, 12 September 1980 (US). By studying closely these patent disclosures, the attempts to realize them, and the subsequent development of the machine, we present, within the framework of generating experimental knowledge, a new account of the invention of the STM. While the realization of the STM was still a long way off, the patent disclosures served as blueprints, marking the changes that had to be introduced on the way from the initial idea to its realization. (shrink)

Review essay covering Godehard Link, ed. One Hundred Years of Russell’s Paradox (de Gruyter 2004).