Results for 'Parent-specific gene-expression'

963 found
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  1. Does intragenomic conflict predict intrapersonal conflict?David Spurrett - 2016 - Biology and Philosophy 31 (3):313-333.
    Parts of the genome of a single individual can have conflicting interests, depending on which parent they were inherited from. One mechanism by which these conflicts are expressed in some taxa, including mammals, is genomic imprinting, which modulates the level of expression of some genes depending on their parent of origin. Imprinted gene expression is known to affect body size, brain size, and the relative development of various tissues in mammals. A high fraction of imprinted (...)
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  2. Exploring Relations between Beliefs about the Genetic Etiology of Virtue and the Endorsement of Parenting Practices.Matt Stichter, Grace Rivera, Matthew Vess, Rebecca Brooker & Jenae Nederhiser - 2021 - Parenting: Science and Practice 21 (2):79-107.
    Objective. We investigated associations between adults’ beliefs about the heritability of virtue and endorsements of the efficacy of specific parenting styles. Design. In Studies 1 (N = 405) and 2 (N = 400), beliefs about both the genetic etiology of virtuous characteristics and parenting were assessed in samples of parents and non-parents. In Study 3 (N = 775), participants were induced to view virtue as determined by genes or as determined by social factors. Heritability beliefs and authoritarian parenting endorsements (...)
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    Divergent Processing of Cell Stress Signals as the Basis of Cancer Progression: Licensing NFκB on Chromatin.Spiros A. Vlahopoulos - 2024 - IJMS 25 (16):8621.
    Inflammation is activated by diverse triggers that induce the expression of cytokines and adhesion molecules, which permit a succession of molecules and cells to deliver stimuli and functions that help the immune system clear the primary cause of tissue damage, whether this is an infection, a tumor, or a trauma. During inflammation, short-term changes in the expression and secretion of strong mediators of inflammation occur, while long-term changes occur to specific groups of cells. Long-term changes include cellular (...)
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  4. The Full Bayesian Significance Test for Mixture Models: Results in Gene Expression Clustering.Julio Michael Stern, Marcelo de Souza Lauretto & Carlos Alberto de Braganca Pereira - 2008 - Genetics and Molecular Research 7 (3):883-897.
    Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixture models, where the number of clusters is predicted via sequential hypothesis tests: at each step, the method considers a mixture model of m components (m = 2 in the first step) and (...)
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  5. Embracing Change with All Four Arms: Post-Humanist Defense of Genetic Engineering.J. Hughes - 1996 - Eubios Journal of Asian and International Bioethics 6 (4):94-101.
    This paper sets out to defend human genetic engineering with a new bioethical approach, post-humanism, combined with a radical democratic political framework. Arguments for the restriction of human genetic engineering, and specifically germ-line enhancement, are reviewed. Arguments are divided into those which are fundamental matters of faith, or "bio-Luddite" arguments, and those which can be addressed through public policy, or "gene-angst" arguments.The four bio-Luddite concerns addressed are: Medicine Makes People Sick; There are Sacred Limits of the Natural Order; Technologies (...)
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  6. A Revolutionary New Metaphysics, Based on Consciousness, and a Call to All Philosophers.Lorna Green - manuscript
    June 2022 A Revolutionary New Metaphysics, Based on Consciousness, and a Call to All Philosophers We are in a unique moment of our history unlike any previous moment ever. Virtually all human economies are based on the destruction of the Earth, and we are now at a place in our history where we can foresee if we continue on as we are, our own extinction. As I write, the planet is in deep trouble, heat, fires, great storms, and record flooding, (...)
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  7. Unifying diseases from a genetic point of view: the example of the genetic theory of infectious diseases.Marie Darrason - 2013 - Theoretical Medicine and Bioethics 34 (4):327-344.
    In the contemporary biomedical literature, every disease is considered genetic. This extension of the concept of genetic disease is usually interpreted either in a trivial or genocentrist sense, but it is never taken seriously as the expression of a genetic theory of disease. However, a group of French researchers defend the idea of a genetic theory of infectious diseases. By identifying four common genetic mechanisms (Mendelian predisposition to multiple infections, Mendelian predisposition to one infection, and major gene and (...)
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  8. The Planteome database: an integrated resource for reference ontologies, plant genomics and phenomics.Laurel Cooper, Austin Meier, Marie-Angélique Laporte, Justin L. Elser, Chris Mungall, Brandon T. Sinn, Dario Cavaliere, Seth Carbon, Nathan A. Dunn, Barry Smith, Botong Qu, Justin Preece, Eugene Zhang, Sinisa Todorovic, Georgios Gkoutos, John H. Doonan, Dennis W. Stevenson, Elizabeth Arnaud & Pankaj Jaiswal - 2018 - Nucleic Acids Research 46 (D1):D1168–D1180.
    The Planteome project provides a suite of reference and species-specific ontologies for plants and annotations to genes and phenotypes. Ontologies serve as common standards for semantic integration of a large and growing corpus of plant genomics, phenomics and genetics data. The reference ontologies include the Plant Ontology, Plant Trait Ontology, and the Plant Experimental Conditions Ontology developed by the Planteome project, along with the Gene Ontology, Chemical Entities of Biological Interest, Phenotype and Attribute Ontology, and others. The project (...)
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  9. Genetic, epigenetic and exogenetic information.Karola Stotz & Paul Edmund Griffiths - 2016 - In Richard Joyce (ed.), The Routledge Handbook of Evolution and Philosophy. New York: Routledge.
    We describe an approach to measuring biological information where ‘information’ is understood in the sense found in Francis Crick’s foundational contributions to molecular biology. Genes contain information in this sense, but so do epigenetic factors, as many biologists have recognized. The term ‘epigenetic’ is ambiguous, and we introduce a distinction between epigenetic and exogenetic inheritance to clarify one aspect of this ambiguity. These three heredity systems play complementary roles in supplying information for development. -/- We then consider the evolutionary significance (...)
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  10. Les mains mortes de la sélection de groupe et de la phénoménologie -Un examen de "l'Individualité et l'Intrication" (Individuality and Entanglement) par Herbert Gintis 357p (2017) (examen révisé 2019).Michael Richard Starks - 2020 - In Bienvenue en Enfer sur Terre : Bébés, Changement climatique, Bitcoin, Cartels, Chine, Démocratie, Diversité, Dysgénique, Égalité, Pirates informatiques, Droits de l'homme, Islam, Libéralisme, Prospérité, Le Web, Chaos, Famine, Maladie, Violence, Intellige. Las Vegas, NV USA: Reality Press. pp. 257-269.
    Depuis Gintis est un économiste senior et j’ai lu certains de ses livres précédents avec intérêt, je m’attendais à un peu plus de perspicacité dans le comportement. Malheureusement, il fait les mains mortes de la sélection de groupe et la phénoménologie dans les pièces maîtresses de ses théories du comportement, et cela invalide en grande partie le travail. Pire encore, puisqu’il montre un si mauvais jugement ici, il remet en question tout son travail précédent. La tentative de ressusciter la sélection (...)
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  11. Complex Systems Biology.Roberto Serra - 2012 - In Vincenzo Fano, Enrico Giannetto, Giulia Giannini & Pierluigi Graziani (eds.), Complessità e Riduzionismo. ISONOMIA - Epistemologica Series Editor. pp. 100-107.
    The term “Complex Systems Biology” was introduced a few years ago [Kaneko, 2006] and, although not yet of widespread use, it seems particularly well suited to indicate an approach to biology which is well rooted in complex systems science. Although broad generalizations are always dangerous, it is safe to state that mainstream biology has been largely dominated by a gene-centric view in the last decades, due to the success of molecular biology. So the one gene - one trait (...)
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  12. Gametogênese Animal: Espermatogênese e Ovogênese.Emanuel Isaque Cordeiro da Silva - manuscript
    GAMETOGÊNESE -/- Emanuel Isaque Cordeiro da Silva Instituto Agronômico de Pernambuco Departamento de Zootecnia – UFRPE Embrapa Semiárido -/- • _____OBJETIVO -/- Os estudantes bem informados, estão a buscando conhecimento a todo momento. O estudante de Veterinária e Zootecnia, sabe que a Reprodução é uma área de primordial importância para sua carreira. Logo, o conhecimento da mesma torna-se indispensável. No primeiro trabalho da série fisiologia reprodutiva dos animais domésticos, foi abordado de forma clara, didática e objetiva os mecanismos de diferenciação (...)
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  13. Complex Organisation and Fundamental Physics.Brian D. Josephson - 2018 - Streaming Media Service, Cambridge University.
    The file on this site provides the slides for a lecture given in Hangzhou in May 2018, and the lecture itself is available at the URL beginning 'sms' in the set of links provided in connection with this item. -/- It is commonly assumed that regular physics underpins biology. Here it is proposed, in a synthesis of ideas by various authors, that in reality structures and mechanisms of a biological character underpin the world studied by physicists, in principle supplying detail (...)
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  14. Genetics, Epigenetics, Paragenetics: Getting Closer to Life.Bhakti Madhava Puri - 2014 - The Harmonizer.
    Gregor Mendel (1822-1884) was the first to explain that certain 'traits' were inherited in plants from one generation to the next. These would later become known as genes. Frederich Miescher in 1869 analyzed a substance from the nucleus of cells, which he therefore called nuclein. Further study of nuclein revealed that it contained elements like hydrogen, oxygen, nitrogen and phosphorous, with a specific ratio of nitrogen to phosphorous. Then in 1878 Albrecht Kossel determined that nuclein contained nucleic acid, from (...)
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  15. Unconscious goals: Specific or unspecific? The potential harm of the goal/gene analogy.Bence Nanay - 2014 - Behavioral and Brain Sciences 37 (2):152-153.
    Huang and Bargh’s definition of goals is ambiguous between ‘specific goals’ – the end-state of a token action I am about to perform – and ‘unspecific goals’ – the end-state of an action-type (without specifying how this would be achieved). The analogy with selfish genes pushes the authors towards the former interpretation, but the latter would provide a more robust theoretical framework.
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  16. The Gene as a Natural Kind.Francesca Bellazzi - 2023 - In José Manuel Viejo & Mariano Sanjuán (eds.), Life and Mind - New Directions in the Philosophy of Biology and Cognitive Sciences. Springer. pp. pp 259–278.
    What is a gene? Does it represent a natural kind, or is it just a tool for genomics? A clear answer to these questions has been challenged by postgenomic discoveries. In response, I will argue that the gene can be deemed a natural kind as it satisfies some requirements for genuine kindhood. Specifically, natural kinds are projectible categories in our best scientific theories, and they represent nodes in the causal network of the world (as in Khalidi. Natural Categories (...)
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  17. Feeding Infants: Choice-Specific Considerations, Parental Obligation, and Pragmatic Satisficing.Clare Marie Moriarty & Ben Davies - 2024 - Ethical Theory and Moral Practice 27 (2):167-183.
    Health institutions recommend that young infants be exclusively breastfed on demand, and it is widely held that parents who can breastfeed have an obligation to do so. This has been challenged in recent philosophical work, especially by Fiona Woollard. Woollard’s work critically engages with two distinct views of parental obligation that might ground such an obligation—based on maximal benefit and avoidance of significant harm—to reject an obligation to breastfeed. While agreeing with Woollard’s substantive conclusion, this paper (drawing on philosophical discussion (...)
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  18. The Right to Parent and Duties Concerning Future Generations.Anca Gheaus - 2016 - Journal of Political Philosophy 24 (1):487-508.
    Several philosophers argue that individuals have an interest-protecting right to parent; specifically, the interest is in rearing children whom one can parent adequately. If such a right exists it can provide a solution to scepticism about duties of justice concerning distant future generations and bypass the challenge provided by the non-identity problem. Current children - whose identity is independent from environment-affecting decisions of current adults - will have, in due course, a right to parent. Adequate parenting requires (...)
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  19. Genes and organisms in the legacy of the modern synthesis.J. Arvid Ågren - 2023 - In T. E. Dickins & B. J. Dickins (eds.), Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory. Springer. pp. 555–568.
    The gene's-eye view of evolution is an influential but contentious perspective on biology. It emerged in the aftermath of the Modern Synthesis and both proponents and detractors have stressed the link between the two. In particular, both the Modern Synthesis and the gene's-eye view have been criticized for overemphasizing the role genes at the expense of organisms in evolutionary explanations. In this chapter, I discuss the connection between the Modern Synthesis and the gene’s-eye view and evaluate the (...)
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  20. Cohesion, Gene flow, and the Nature of Species.Matthew J. Barker & Robert A. Wilson - 2010 - Journal of Philosophy 107 (2):59-77.
    A far-reaching and influential view in evolutionary biology claims that species are cohesive units held together by gene flow. Biologists have recognized empirical problems facing this view; after sharpening the expression of the view, we present novel conceptual problems for it. At the heart of these problems is a distinction between two importantly different concepts of cohesion, what we call integrative and response cohesion. Acknowledging the distinction problematizes both the explanandum of species cohesion and the explanans of (...) flow that are central to the view we discuss. We conclude by tracing four broader implications for the study and conceptualization of species. (shrink)
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  21. Genes, Causation and Intentionality.Marcel Weber - 2005 - History and Philosophy of the Life Sciences 27 (3/4):399-411.
    I want to exhibit the deeper metaphysical reasons why some common ways of describing the causal role of genes in development and evolution are problematic. Specifically, I show why using the concept of information in an intentional sense in genetics is inappropriate, even given a naturalistic account of intentionality. Furthermore, I argue that descriptions that use notions such as programming, directing or orchestrating are problematic not for empirical reasons, but because they are not strictly causal. They are intentional. By contrast, (...)
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  22. Genes, identity, and the expressivist critique.Robert Sparrow - 2008 - In Loane Skene and Janna Thompson (ed.), The Sorting Society. Cambridge University Press. pp. 111-132..
    In this paper, I explore the “expressivist critique” of the use of prenatal testing to select against the birth of persons with impairments. I begin by setting out the expressivist critique and then highlighting, through an investigation of an influential objection to this critique, the ways in which both critics and proponents of the use of technologies of genetic selection negotiate a difficult set of dilemmas surrounding the relationship between genes and identity. I suggest that we may be able to (...)
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  23. Networks of Gene Regulation, Neural Development and the Evolution of General Capabilities, Such as Human Empathy.Alfred Gierer - 1998 - Zeitschrift Für Naturforschung C - A Journal of Bioscience 53:716-722.
    A network of gene regulation organized in a hierarchical and combinatorial manner is crucially involved in the development of the neural network, and has to be considered one of the main substrates of genetic change in its evolution. Though qualitative features may emerge by way of the accumulation of rather unspecific quantitative changes, it is reasonable to assume that at least in some cases specific combinations of regulatory parts of the genome initiated new directions of evolution, leading to (...)
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  24. Genes and Virtue: Exploring how heritability beliefs shape conceptions of virtue and its development.Matt Stichter, Matthew Vess, Rebecca Brooker & Jenae Nederhiser - 2019 - Behavioral Genetics 49 (2):168-174.
    In this paper, we provide an overview of our ongoing project in the Genetics and Human Agency Initiative sponsored by the John Templeton Foundation. Our project focuses on the ways that lay beliefs about the heritability of virtue influence reasoning about the nature of virtue, parenting behaviors, and the development of virtue in children. First, we provide philosophical perspectives on the nature of virtue and suggest that viewing virtue as a malleable skill may have important advantages. Next, we review theory (...)
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  25. Really expressive presuppositions and how to block them.Teresa Marques & Manuel García-Carpintero - 2020 - Grazer Philosophische Studien 97 (1):138-158.
    Kaplan (1999) argued that a different dimension of expressive meaning (“use-conditional”, as opposed to truth-conditional) is required to characterize the meaning of pejoratives, including slurs and racial epithets. Elaborating on this, writers have argued that the expressive meaning of pejoratives and slurs is either a conventional implicature (Potts 2007) or a presupposition (Macià 2002 and 2014, Schlenker 2007, Cepollaro and Stojanovic 2016). We argue that an expressive presuppositional theory accounts well for the data, but that expressive presuppositions are not just (...)
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  26. Genes, Affect, and Reason: Why Autonomous Robot Intelligence Will Be Nothing Like Human Intelligence.Henry Moss - 2016 - Techné: Research in Philosophy and Technology 20 (1):1-15.
    Abstract: Many believe that, in addition to cognitive capacities, autonomous robots need something similar to affect. As in humans, affect, including specific emotions, would filter robot experience based on a set of goals, values, and interests. This narrows behavioral options and avoids combinatorial explosion or regress problems that challenge purely cognitive assessments in a continuously changing experiential field. Adding human-like affect to robots is not straightforward, however. Affect in organisms is an aspect of evolved biological systems, from the taxes (...)
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  27. Good parents would not fulfil their obligation to genetically enhance their unborn children.R. Tonkens - 2011 - Journal of Medical Ethics 37 (10):606-610.
    The purpose of this paper is to unveil the incompleteness of John Harris' view that parents have a moral obligation to genetically enhance their unborn children. Specifically, here two main conclusions are proposed: (1) at present there exist insufficient empirical data for determining whether prenatal genetic enhancement (PGE) is a moral obligation on prospective parents. Although the purpose of PGE research would be to determine the extent to which PGE is safe and effective, the task of determining the veracity of (...)
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  28. The Theory of the Selfish Gene Applied to the Human Population.Richard Startup - 2021 - Advances in Anthropology 11 (3):179-200.
    In a study drawing from both evolutionary biology and the social sciences, evidence and argument is assembled in support of the comprehensive appli- cation of selfish gene theory to the human population. With a focus on genes giving rise to characteristically-human cooperation (“cooperative genes”) in- volving language and theory of mind, one may situate a whole range of pat- terned behaviour—including celibacy and even slavery—otherwise seeming to present insuperable difficulties. Crucially, the behaviour which tends to propa- gate the cooperative (...)
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  29. Information Dynamics across Linked Sub-Networks: Germs, Genes, and Memes.Patrick Grim, Daniel J. Singer, Christopher Reade & Stephen Fisher - 2011 - In Patrick Grim, Daniel J. Singer, Christopher Reade & Stephen Fisher (eds.), Proceedings, AAAI Fall Symposium on Complex Adaptive Systems: Energy, Information and Intelligence. AAAI Press.
    Beyond belief change and meme adoption, both genetics and infection have been spoken of in terms of information transfer. What we examine here, concentrating on the specific case of transfer between sub-networks, are the differences in network dynamics in these cases: the different network dynamics of germs, genes, and memes. Germs and memes, it turns out, exhibit a very different dynamics across networks. For infection, measured in terms of time to total infection, it is network type rather than degree (...)
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  30. A Project View of the Right to Parent.Benjamin Lange - 2023 - Journal of Applied Philosophy 1:1-23.
    The institution of the family and its importance have recently received considerable attention from political theorists. Leading views maintain that the institution’s justification is grounded, at least in part, in the non-instrumental value of the parent-child relationship itself. Such views face the challenge of identifying a specific good in the parent-child relationship that can account for how adults acquire parental rights over a particular child—as opposed to general parental rights, which need not warrant a claim to (...) one’s biological progeny. I develop a view that meets this challenge. This Project View identifies the pursuit of a parental project as a distinctive non-instrumentally valuable good that provides a justification for the family and whose pursuit is necessary and sufficient for the acquisition of parental rights. This view grounds moral parenthood in a normative relation as opposed to a biological one, supports polyadic forms of parenting, and provides plausible guidance in cases of assisted reproduction. (shrink)
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  31. Judge-Specific Sentences about Personal Taste, Indexical Contextualism, and Disagreement.Marián Zouhar - 2022 - Filozofia Nauki 30 (4):15-39.
    The paper aims to weaken a widespread argument against indexical contextualism regarding matters of personal taste. According to indexical contextualism, an utterance of “T is tasty” (where T is an object of taste) expresses the proposition that T is tasty for J (where J is a judge). This argument suggests that indexical contextualism cannot do justice to our disagreement intuitions regarding typical disputes about personal taste because it has to treat conversations in which one speaker utters “T is tasty” and (...)
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  32. In it Together? An Exploration of the Moral Duties of Co‐parents.Daniela Cutas & Sabine Hohl - 2021 - Journal of Applied Philosophy 38 (5):809-823.
    Even though co‐parenthood is one of the most significant close personal relationships that people can have, there is relatively little philosophical work on the moral duties that co‐parents owe each other. This may be due to the increasingly questionable assumption, still common in our societies, that co‐parenthood arises naturally from marriage or romantic coupledom and thus that commitment to a co‐parent evolves from a commitment to a marital or romantic partner. In this article, we argue that co‐parenthood should be (...)
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  33. Expressing first-person authority.Matthew Parrott - 2015 - Philosophical Studies 172 (8):2215-2237.
    Ordinarily when someone tells us something about her beliefs, desires or intentions, we presume she is right. According to standard views, this deferential trust is justified on the basis of certain epistemic properties of her assertion. In this paper, I offer a non-epistemic account of deference. I first motivate the account by noting two asymmetries between the kind of deference we show psychological self-ascriptions and the kind we grant to epistemic experts more generally. I then propose a novel agency-based account (...)
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  34. Asexual organisms, identity and vertical gene transfer.Gunnar Babcock - 2020 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 81:101265.
    This paper poses a problem for traditional phylogenetics: The identity of organisms that reproduce through fission can be understood in several different ways. This prompts questions about how to differentiate parent organisms from their offspring, making vertical gene transfer unclear. Differentiating between parents and offspring stems from what I call the identity problem. How the problem is resolved has implications for phylogenetic groupings. If the identity of a particular asexual organism persists through fission, the vertical lineage on a (...)
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  35. Expression as Realization: Speakers' Interests in Freedom of Speech.Jonathan Gilmore - 2011 - Law and Philosophy 30 (5):517-539.
    I argue for the recognition of a particular kind of interest that one has in freedom of expression: an interest served by expressive activity in forming and discovering one’s own beliefs, desires, and commitments. In articulating that interest, I aim to contribute to a family of theories of freedom of expression that find its justification in the interests that speakers have in their own speech or thought, to be distinguished from whatever interests they may also have as audiences (...)
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  36. Misleading Expressions: The Brentano-Ryle Connection.Arnaud Dewalque - 2021 - In Arnaud Dewalque, Charlotte Gauvry & Sébastien Richard (eds.), Philosophy of Language in the Brentano School: Reassessing the Brentanian Legacy. Palgrave-Macmillan. pp. 95-118.
    This chapter argues that Gilbert Ryle’s account of misleading expressions, which is rightly considered a milestone in the history of analytic philosophy, is continuous with Brentano’s. Not only did they identify roughly the same classes of misleading expressions, but their analyses are driven by a form of ontological parsimony which sharply contrasts with rival views in the Brentano School, like those of Meinong and Husserl. Section 1 suggests that Ryle and Brentano share a similar notion of analysis. Section 2 spells (...)
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  37. Expressive meaning in music: Generality versus particularity.Krzysztof Guczalski - 2005 - British Journal of Aesthetics 45 (4):342-367.
    The dilemma referred to in the title occurs in many contexts concerned with expressive meaning in art, and especially music, which suggests that the issue it raises will be central to any complete theory of musical expressiveness. One notable attempt to resolve the paradox of simultaneous generality and particularity in music is in Aaron Ridley’s book Music, Value and the Passions. I show why I consider his account unsatisfactory and then propose my own resolution of the paradox. It takes the (...)
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  38. Quality of Parenting and Its Role In Reducing Violence Against Women in Arab Societies.Atef Hosni Elasouly - 2018 - International Journal of Academic Multidisciplinary Research (IJAMR) 2 (5):1-6.
    Abstract: In the wide range of issues of violence against women in Arab and Western societies, Professor Brian Sykes wrote about how the future can be without men by looking at the male dominance of Y chromosome on female X chromosome and trying to trace the first forms of male dominance The World To the extent that some geneticists think theoretically that a female ovum is fertilized by an ovum from another female to produce a new human being is of (...)
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  39. Specificity and Redundant Causation.Henning Strandin - manuscript
    In this paper I present a metaphysically minimalist but theoretically strong version of fact causation, in which the causal relata constitute a full Boolean algebra, mirroring the entailment relation of the sentences that express them. I suggest a generalization of the notion of multiple realizability of causes in terms of specificity of facts, and employ this in an interpretation of what goes on in cases of apparently redundant causation.
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  40. Mind the Gap: Expressing affect with hyperbole and hyperbolic compounds.Mihaela Popa-Wyatt - 2020 - John Benjamins.
    Hyperbole is traditionally understood as exaggeration. Instead, in this paper, we shall define it not just in terms of its form, but in terms of its effects and its purpose. Specifically, we characterize its form as a shift of magnitude along a scale of measurement. In terms of its effect, it uses this magnitude shift to make the target property more salient. The purpose of hyperbole is to express with colour and force that the target property is either greater or (...)
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  41. Generics: some (non) specifics.Anne Bosse - 2021 - Synthese (5-6):14383-14401.
    This paper is about an underappreciated aspect of generics: their non-specificity. Many uses of generics, utterances like ‘Seagulls swoop down to steal food’, express non-specific generalisations which do not specify their quantificational force or flavour. I consider whether this non-specificity arises as a by-product of context-sensitivity or semantic incompleteness but argue instead that generics semantically express non-specific generalisations by default as a result of quantifying existentially over more specific ones.
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  42. Expressing Moral Belief.Sebastian Hengst - 2022 - Dissertation, Ludwig Maximilians Universität, München
    It is astonishing that we humans are able to have, act on and express moral beliefs. This dissertation aims to provide a better philosophical understanding of why and how this is possible especially when we assume metaethical expressivism. Metaethical expressivism is the combination of expressivism and noncognitivism. Expressivism is the view that the meaning of a sentence is explained by the mental state it is conventionally used to express. Noncognitivism is the view that the mental state expressed by a moral (...)
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  43. A semantic approach for knowledge capture of microRNA-target gene interactions.Jingshan Huang, Fernando Gutierrez, Dejing Dou, Judith A. Blake, Karen Eilbeck, Darren A. Natale, Barry Smith, Yu Lin, Xiaowei Wang & Zixing Liu - 2015 - In Jingshan Huang, Fernando Gutierrez, Dejing Dou, Judith A. Blake, Karen Eilbeck, Darren A. Natale, Barry Smith, Yu Lin, Xiaowei Wang & Zixing Liu (eds.), IEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM 2015),. pp. 975-982.
    Research has indicated that microRNAs (miRNAs), a special class of non-coding RNAs (ncRNAs), can perform important roles in different biological and pathological processes. miRNAs’ functions are realized by regulating their respective target genes (targets). It is thus critical to identify and analyze miRNA-target interactions for a better understanding and delineation of miRNAs’ functions. However, conventional knowledge discovery and acquisition methods have many limitations. Fortunately, semantic technologies that are based on domain ontologies can render great assistance in this regard. In our (...)
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  44. The multimodal construction of political personae through the strategic management of semiotic resources of emotion expression.Gheorghe-Ilie Farte & Nicolae-Sorin Dragan - 2022 - Social Semiotics 32 (3):1-25.
    This paper presents an analytical framework for analyzing how multimodal resources of emotion expression are semiotically materialized in discursive interactions specific to political discourse. Interested in how political personae are emotionally constructed through multimodal meaning-making practices, our analysis model assumes an interdisciplinary perspective, which integrates facial expression analysis – using FaceReader™ software –, the theory of emotional arcs and bodily actions (hand gestures) analysis that express emotions, in the analytical framework of multimodality. The results show how the (...)
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  45. Expressing set-size equality.John Corcoran & Gerald Rising - 2015 - Bulletin of Symbolic Logic 21 (2):239.
    The word ‘equality’ often requires disambiguation, which is provided by context or by an explicit modifier. For each sort of magnitude, there is at least one sense of ‘equals’ with its correlated senses of ‘is greater than’ and ‘is less than’. Given any two magnitudes of the same sort—two line segments, two plane figures, two solids, two time intervals, two temperature intervals, two amounts of money in a single currency, and the like—the one equals the other or the one is (...)
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  46. Compositionality and Expressive Power: Comments on Pietroski.Elmar Unnsteinsson - 2020 - Croatian Journal of Philosophy 20 (3):295-310.
    Paul Pietroski has developed a powerful minimalist and internalist alternative to standard compositional semantics, where meanings are identified with instructions to fetch or assemble human concepts in specific ways. In particular, there appears to be no need for Fregean Function Application, as natural language composition only involves processes of combining monadic or dyadic concepts, and Pietroski’s theory can then, allegedly, avoid both singular reference and truth conditions. He also has a negative agenda, purporting to show, roughly, that the vocabulary (...)
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  47. Paternalism, supportive decision making and expressive respect.Linda Barclay - 2024 - Journal of Ethics and Social Philosophy 27 (1):1-29.
    It has been argued by disability advocates that supported decision-making must replace surrogate, or substituted, decision-making for people with cognitive disabilities. From a moral perspective surrogate decision-making it is said to be an indefensible form of paternalism. At the heart of this argument against surrogate decision-making is the belief that such paternalistic action expresses something fundamentally disrespectful about those upon whom it is imposed: that they are inferior, deficient or child-like in some way. Contrary to this widespread belief, I will (...)
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  48. Can we say what we mean?: Expressibility and background.Jesús Navarro - 2009 - Pragmatics and Cognition 17 (2):283-308.
    The aim of this paper is to discuss a basic assumption tacitly shared by many philosophers of mind and language: that whatever can be meant, can be said. It specifically targets John Searle's account of this idea, focusing on his Principle of Expressibility . In the first part of the paper, PE is exposed underlining its analyticity and its relevance for the philosophy of language , mind , society and action . In the critical part, the notion of Background is (...)
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  49. (1 other version)Privacy, Democracy and Freedom of Expression.Annabelle Lever - 2015 - In Beate Roessler & Dorota Mokrosinska (eds.), The Social Dimensions of Privacy. Cambridge University Press. pp. 67-69.
    Must privacy and freedom of expression conflict? To witness recent debates in Britain, you might think so. Anything other than self-regulation by the press is met by howls of anguish from journalists across the political spectrum, to the effect that efforts to protect people’s privacy will threaten press freedom, promote self-censorship and prevent the press from fulfilling its vital function of informing the public and keeping a watchful eye on the activities and antics of the powerful.[Brown, 2009, 13 January]1 (...)
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  50. “Treating the Sceptic with Genuine Expression of Feeling. Wittgenstein’s Later Remarks on the Psychology of Other Minds”.Edoardo Zamuner - 2004 - In A. Roser & R. Raatzsch (eds.), Jahrbuch der Deutschen Ludwig Wittgenstein Gesellschaft. Peter Lang Verlag.
    This paper is concerned with the issue of authenticity in Wittgenstein’s philosophy of psychology. In the manuscripts published as Letzte Schriften über die Philosophie der Psychologie – Das Innere und das Äußere, the German term Echtheit is mostly translated as ‘genuineness’. In these manuscripts, Wittgenstein frequently uses the term as referring to a feature of the expression of feeling and emotion: -/- […] I want to say that there is an original genuine expression of pain; that the (...) of pain therefore is not equally connected to the pain and to the pretence. (LW II, p. 55) -/- “This weeping gives the impression of being genuine” – so there is such a thing as genuine weeping. […]. (LW II, p. 87) -/- […] Genuineness and falseness are not the only essential characteristics of an expression of feeling. […]. (LW II, p. 90) -/- Wittgenstein contrasts the genuineness of the expressions with the possibility that the expressions are feigned. It seems to me that Wittgenstein is trying to discredit a specific version of the sceptical claim that we do not know other minds. I will refer to it as the sceptical innuendo. The sceptical innuendo says that every expression of feeling and emotion may be pretended. Wittgenstein’s approach to the issue reflects his later interest in the philosophy of psychology and, in particular, the problem of the ascription of psychological states (P-ascriptions) on the basis of someone else’s expression of feeling or emotion. Thus, the attempt to reject the sceptical innuendo is done mainly by means of conceptual and psychological arguments. Let’s look at this short dialogue between the sceptic and Wittgenstein. The former asks „How do you know that someone else is in a certain psychological state?“ Wittgenstein’s first reply is „I know that he is glad because I see him“. But the sceptic cannot be very happy with this reply. The sceptic’s next question is: „How do you know that he is really glad and he is not pretending?“ Wittgenstein’s response is not a direct refutation but is composed of a number of related reasons. These may be summed up in three arguments: -/- (i) A psychological argument from the very nature of the expressions. The expressions are meant to be natural symptoms of someone else’s psychological state (P-state). -/- (ii) A conceptual argument about the nature of pretence. It claims that pretence is a psychological property which is rightly ascribed when an observer has evidence for it. -/- (iii) A psychological argument from genuineness. It claims that we are committed to accept people’s expressions of feeling and emotion as genuine. (shrink)
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