Although Henry Lee is often recognized to be an important early critic of Locke's 'way of ideas', his Anti-Scepticism (1702) has hardly received the scholarly attention it deserves. This paper seeks to fill that lacuna. It argues that Lee's criticism of Locke's alleged representationalism was original, and that it was quite different from the more familiar kind of criticism that was launched against Locke's theory of ideas by such thinkers as John Sergeant and Thomas Reid. In addition, the paper (...) offers an interpretation of Lee’s claim that, pace Locke, attempts to prove the veridicality of our cognitive apparatus are fundamentally misguided. (shrink)

The goal of this paper is to critically examine the objections of John Locke’s contemporaries against the theory of substance or substratum. Locke argues in Essay that substratum is the bearer of the properties of a particular substance. Locke also claims that we have no knowledge of substratum. But Locke’s claim about our ignorance as to what substratum is, is contentious. That is, if we don’t know what substratum is, then what is the point of proposing it as a bearer (...) of properties? This question underlies the criticism Locke’s contemporaries raise against the notion of substratum. In section I, I lay out the context for Locke’s theory of substratum by pointing out his main motivation in proposing his theory. In section II, I give a brief analysis of the theory of substratum. In section III, I discuss the objections of Locke’s contemporaries against the theory of substratum.1 I focus on Edward Stillingfleet, Lee Henry, G. W. Leibniz and John Sergeant. In section IV, I conclude that there is no warrant to dismiss Locke’s theory of substance. (shrink)

OBJETIVO -/- O estudante de Zootecnia e de Veterinária, quando se depara com a produção animal, um dos pilares importantes é a reprodução, uma vez que é a perpetuação da espécie, seja para gerar filhas de uma vaca campeã em produção leiteira e de um touro com rusticidade e com aptidão produtiva de corte, ou mesmo para reposição de um plantel, o mesmo deve estar consciente de que esse ramo é de extrema responsabilidade, já que estará intimamente lidando com a (...) vida e com um investimento que pode gerar lucros em demasia para a propriedade ou, se mal feito o manejo da reprodução, trazer sérios transtornos para a mesma. -/- Nesse trabalho, o estudante revisará os sucessos da puberdade e estacionalidade reprodutiva relacionando-os com os processos endócrinos e os fatores que afetam sua manifestação como os nutricionais, para compreender a maneira ao qual podem ser manipuladas. -/- -/- • _____INTRODUÇÃO -/- A puberdade marca o início da vida reprodutiva do animal, permitindo integrar o indivíduo ao seu ciclo produtivo. A estacionalidade é uma característica de adaptação que algumas espécies desenvolveram para fazer garantir a eficiência da reprodução e a sobrevivência dos filhotes. -/- -/- • _____PUBERDADE -/- A puberdade é atingida quando o animal é capaz de produzir e liberar gametas viáveis e funcionais (férteis). Na fêmea esse fato ocorre na primeira ovulação, que geralmente coincide com a manifestação do comportamento do cio; e nos machos durante a primeira ejaculação com espermatozoides viáveis. -/- Do ponto de vista da produção animal, puberdade prematura ou precoce, é importante para poder permitir a incorporação dos animais ao ciclo produtivo o mais rapidamente possível. No caso de touros holandeses, por exemplo, é desejável que produzam sêmen precocemente para incorporá-los a prova de progênie; nas fêmeas, entretanto, deve-se considerar que nem sempre é conveniente usar o primeiro ciclo ou cio para reprodução. É o caso das marrãs (porcas primíparas), onde é benéfico esperar até o segundo ou terceiro estro para aumentar o tamanho da ninhada. Também pode ser vantajoso esperar que o indivíduo alcance sua maturidade sexual, que ocorre quando a fêmea consegue se reproduzir sem sofrer efeitos adversos. A ovelha nascida na primavera, por exemplo, pode engravidar no outono seguinte e dar à luz no primeiro ano de vida, mas seu crescimento pode ser afetado; o mesmo ocorre com a novilha, em que o acasalamento precoce pode promover distorcia por falta de desenvolvimento pélvico. -/- A puberdade é um processo gradual e está intimamente relacionada à taxa de crescimento e ao metabolismo energético. O recém-nascido usa energia para funções vitais, principalmente termorregulação; esse feito se deve ao fato de os jovens possuírem uma superfície corporal muito elevada em relação ao seu volume. Durante o desenvolvi-mento subsequente dos tecidos também há prioridade no uso de nutrientes, que inicialmente favorecem o desenvolvimento do tecido ósseo e muscular, e uma vez que estes atingem determinado tamanho de acordo com as condições genéticas do indivíduo, inicia-se o desenvolvimento do tecido adiposo, que é indicativa de um reservatório de energia. É importante ressaltar que existe uma interação entre a genética e o meio ambiente, de forma que o potencial genético só será expresso se o meio ambiente for favorável. -/- Para que a ovulação ocorra, é necessário considerar o funcionamento do eixo hipotálamo-hipófise-gonodal. O aumento da frequência pulsátil do GnRH hipotalâmico e em consequência do LH hipofisário provoca a maturação do folículo em nível gonodal, o que aumenta a produção de estrógenos. O aumento dos estrogênios causa, por feedback positivo no hipotálamo, a liberação do pico pré-ovulatório de LH e, consequentemente, a ovulação. Na fase pré-púbere, a frequência dos pulsos de GnRH e LH é muito baixa e insuficiente para provocar a maturação folicular, pois o hipotálamo é inibido e, portanto, não ocorre ovulação. -/- A geração pulsátil de GnRH no momento reprodutivo adequado para desencadear o início da puberdade depende de uma rede neural complexa que, além dos neurônios GnRH, inclui outros neurônios e células da glia; ele também integra vários sinais internos e externos para o corpo. A morfologia dos neurônios GnRH também é única, uma vez que seus dendritos também podem funcionar como axônios, dando-lhes uma função distinta. A geração de pulsos também indica a necessidade de sincronização entre subpopulações de neurônios GnRH, que, acima de tudo, parece ser extrínseca a esses neurônios e envolve múltiplos hormônios e neurotransmissores -/- Se dois níveis de conexões aferentes são considerados, estima-se que cada neurônio de GnRH pode ser conectado a cerca de cinco milhões de outros neurônios; milhares de genes, então, podem estar envolvidos no processo da puberdade. A importância funcional e hierárquica de cada um desses genes no controle dos neurônios GnRH, juntamente com outros fatores neuronais e gliais, pode diferir entre as espécies. Existem, no entanto, componentes fundamentais que parecem ser comuns a todos os mamíferos e que se situam nos níveis hierárquicos mais elevados, ajudando a compreender a progressão do processo puberal. Assim, todas as espécies de mamíferos estudadas, por exemplo, têm aglomerados de neurônios kisspeptinérgicos (que secretam kisspeptina), envolvidos na regulação da secreção tônica e secreção cíclica de GnRH, que também se classifica como o elemento mais alto na hierarquia desse complexo neuronal após considerar os neurônios GnRH. -/- Sabe-se que o eixo hipotálamo-hipofisário-gonodal está ativo desde as primeiras fases da vida do indivíduo, mesmo antes do nascimento em certas espécies. A secreção de GnRH, no entanto, é suprimida mais tarde no desenvolvimento e permanece dessa forma até o período pré-púbere, quando será reativada gradualmente. -/- Por várias décadas, a supressão e reinicialização dos pulsos de GnRH foi atribuída a uma hipótese conhecida como teoria gonadostat que afirma que o centro tônico do hipotálamo é inibido devido à sua sensibilidade ao mecanismo de feedback negativo dos esteroides gonodais, é aumentado; portanto, o GnRH e a consequente secreção de gonadotrofinas (FSH e LH) são insuficientes para a ocorrência da maturação folicular e espermatogênese. Essa sensibilidade diminui progressivamente à medida que a puberdade se aproxima. -/- Sabe-se agora que existem fatores não gonodais que agem em paralelo com os esteroides para mediar mudanças no feedback negativo que também são específicos da espécie. -/- Na fêmea, o centro gerador de pulso cíclico também deve ser considerado, o qual é responsável por iniciar a primeira ovulação. O centro cíclico é composto por uma segunda subpopulação de neurônios GnRH que é reativada por meio de uma complexa interação entre vários sistemas neuronais inibitórios (que devem reduzir progressiva-mente sua influência) e outros sistemas excitatórios, que, por sua vez, operam por meio de diferentes neurotransmissores, como o ácido γ-amino-butírico (GABA) e seus receptores, glutamato, óxido nítrico e neuropeptídio Y (NPY). Esses fatores, juntamente com as alterações morfológicas observadas nos neurônios do GnRH à medida que a puberdade se aproxima, e com as interações e sinais aferentes das células gliais, levam a um padrão de progressão linear que culminará na reativação do centro cíclico. Esse processo era conhecido anteriormente como teoria da maturação central e faz parte das mudanças que configuram o processo para chegar à puberdade. A elevação nas concen-trações de estradiol subsequente à reativação gradual do centro gerador de pulso tônico GnRH provavelmente permitirá a maturação final do centro cíclico. -/- A forma como cada organismo estabelece o momento certo para iniciar as mudanças que levam à puberdade é conhecido; a existência de algum mecanismo neurobiológico que constitui um relógio interno pode ser considerada. No entanto, esse mecanismo afetaria principalmente o desenvolvimento neuronal no nível central; também seria difícil compará-lo com a maneira pela qual fatores externos ao indivíduo afetam o início da puberdade. Nessa perspectiva, um sistema que permita receber informações completas sobre o crescimento e desenvolvimento do indivíduo poderia ser mais prático. Os mediadores desse sistema incluem o hormônio do crescimento, IGF-I, leptina e outros substratos metabólicos. A leptina em particular, que sinaliza as reservas de tecido adiposo, é um dos elementos mais importantes e, embora não determine quando começa a puberdade, se atua como fator permissivo para que o processo progrida, uma vez que excede um nível limite. A consideração do estágio de desenvolvimento do animal para o início da puberdade era anteriormente conhecida como o peso corporal crítico ou teoria do lipostato. É importante considerar que as três teorias mencionadas não são exclusivas. -/- O mecanismo da puberdade nos machos é semelhante ao já descrito; entretanto, deve-se lembrar que no macho o centro cíclico não está ativo. À medida que a puberdade se aproxima, o crescimento testicular é desencadeado e, em ruminantes e suínos, o pênis que estava preso à mucosa prepucial é gradualmente liberado. -/- -/- • _____FATORES QUE INFLUENCIAM A PUBERDADE -/- Os animais podem manifestar a puberdade de três formas diferentes. Pode ser tardia e o animal demorar para estar apto a reprodução; precoce e o animal entrar na vida reprodutiva antes do esperado ou pode ser normal e o animal estar com boa conformação e idade. Para tanto, alguns fatores podem interferir à manifestação da puberdade pelos animais como a genética, idade e peso, nutrição, fotoperíodo e o próprio manejo adotado. -/- -/- Genética -/- O genótipo afeta a idade da puberdade, pois algumas raças são anteriores a outras. Nos bovinos, as raças europeias atingem a puberdade antes dos zebuínos, isto é, uma novilha ou novilho da raça holandesa atinge a puberdade primeiro que os animais da mesma idade e do mesmo peso da raça nelore, por exemplo. -/- Da mesma forma, as porcas da raça chinesa Meishan atingem a puberdade por volta dos 115 dias de idade, metade da idade das raças brancas. As ovelhas de raças de corte, da mesma forma, são mais precoces que os produtores de lã. As raças pequenas, da mesma forma, são geralmente mais precoces, pelo menos em bovinos (jersey x guzerá) e em caninos. Os híbridos, por outro lado, apresentam puberdade mais precoce que os puros, devido ao efeito da heterose. Por este motivo, em certas espécies são utilizadas linhas híbridas. -/- -/- Idade e peso -/- A tabela 1 mostra a idade média de início da puberdade em espécies domésticas. O peso vivo (PV) adulto é mais relevante para a idade na puberdade nos ruminantes, enquanto em suínos é menos decisivo. A tabela também apresenta a porcentagem de peso corporal necessária para a puberdade ocorrer de forma natural. -/- -/- Tabela 1: Idade e peso a puberdade das espécies domésticas -/- Espécie -/- Fêmea (meses) -/- Macho (meses) -/- PV adulto (%) -/- Gado holandês -/- 11 (8-15) -/- 11 (7-18) -/- 30-40 -/- Gado brahman -/- 19 -/- 17 -/- 45-60 -/- Caprinos e ovinos -/- 7 (4-14) -/- 7 (6-9) -/- 40-60 -/- Suínos -/- 6 (5-7) -/- 7 (5-8) -/- 75 -/- Equinos -/- 18 (12-19) -/- 14 (10-24) -/- - -/- Caninos -/- 12 (6-24) -/- 9 (5-12) -/- - -/- Felinos -/- 8 (4-12) -/- 9 (8-10) -/- - -/- Fonte: VALENCIA, 2018. -/- Nutrição -/- Como a puberdade está relacionada à taxa de crescimento, os animais que recebem uma nutrição adequada e balanceada apresentarão puberdade em uma idade mais jovem, ou seja, mais precocemente; ao contrário, a puberdade será tardia nos animais que sofreram restrição alimentar, que estão desnutridos ou que tiveram seu crescimento afetado por doenças infecciosas ou parasitárias. A superalimentação também não é recomendada, pois pode alterar tanto os sinais que são recebidos pelo hipotálamo quanto sua resposta a eles. -/- Logo, o manejo alimentar adotado deve estar de acordo com as normas estabeleci-das pelos especialistas na área, principalmente no tocante as exigências nutricionais que devem servir de regra na propriedade. Sendo assim, os animais entrarão em puberdade com as taxas de alta qualidade o que afetará positivamente na prole futura e dará retorno lucrativo ao proprietário. -/- -/- Época do ano (Fotoperíodo) -/- Em fêmeas de espécies sazonais, como ovelhas e cabras, existem certos requisitos de fotoperíodo que devem ser atendidos para que a puberdade ocorra. Nessas espécies, um período de exposição a dias longos é necessário, seguido por outro de exposição a dias curtos. Na verdade, os cordeiros e cabritos nascidos fora da estação, mesmo que tenham atingido o peso necessário, terão que esperar até o outono seguinte (a estação reprodutiva) para atingir a puberdade. Os machos, por outro lado, não estão sujeitos a essas limitações nos requisitos fotoperiódicos para apresentar a puberdade. -/- Em novilhas nascidas no outono, por outro lado, a puberdade ocorre antes de um ano de idade, no verão seguinte ou no início do outono, mais cedo do que nas nascidas na primavera, devido à exposição a longos dias durante os primeiros seis meses do ano após seu nascimento aceleram seu crescimento. Em gatos, o aumento do fotoperíodo também acelera o início da puberdade. -/- Em ovelhas e novilhas, a primeira ovulação que ocorre ao entrar na puberdade é silenciosa; ou seja, não é acompanhada de sinais comportamentais de cio como a micção frequente, inchamento da vulva, uma montando a outra e deixando-se montar etc., pois para que esse comportamento se manifeste, o sistema nervoso necessita de uma pré-sensibilização com progesterona que não estará presente até o próximo ciclo, após o desenvolvimento do corpo lúteo vindo desta primeira ovulação. -/- -/- Sociossexual -/- A interação de indivíduos da mesma espécie ou a presença ou ausência de sinais de bioestimulação, como feromônios, pode afetar o período de puberdade. A puberdade, por exemplo, é atrasada em porcas criadas individualmente em comparação com porcas criadas em grupo. Além disso, na porca, ovelha e cabra, a exposição ao macho estimula as fêmeas e a puberdade aparece mais precocemente. -/- -/- Manejo -/- Certas práticas de manejo podem acelerar a puberdade, especialmente no período pré-púbere. Em porcas próximas à puberdade, por exemplo, o estresse causado por procedimentos, como o transporte de um local para outro ou a exposição ao macho, faz com que apareça o estro em torno de sete dias após a realização do manejo mencionado. -/- -/- • _____ESTACIONALIDADE REPRODUTIVA -/- A estacionalidade ou sazonalidade reprodutiva é uma estratégia evolutiva que se desenvolveu em algumas espécies; tende a tornar a reprodução mais eficiente. Nos países de latitudes distantes do equador, o objetivo é que as crias nasçam na primavera, época do ano mais favorável, graças à abundância de alimentos e às amenas condições climáticas. No caso da ovelha, cuja gestação dura cinco meses, para que os partos ocorram na primavera, ela deve engravidar no outono (figura 1), quando os dias são curtos; enquanto a égua, tendo uma gestação de aproximadamente 11 meses, deve conceber na primavera, quando os dias são longos; assim, o parto ocorrerá na primavera do ano seguinte (figura 2). -/- -/- Figura 1: Esquema ilustrativo da estacionalidade reprodutiva na espécie ovina. Fonte: PIRES et al., 2011. -/- -/- Esta característica evolutiva desenvolvida pela seleção natural na maioria das espécies silvestres e ainda é conservado por algumas espécies domésticas, como ovelhas, cabras, cavalos e gatos. Em bovinos e suínos, ao contrário, a domesticação levou à perda quase total da estacionalidade reprodutiva. -/- A estacionalidade reprodutiva é codificada nos genes; significa então que a seleção natural favoreceu a propagação de genes que permitiam acoplar a hora do nascimento com a melhor época do ano, por isso passou a ser considerada um método anticoncepcional natural. -/- -/- Figura 2: ciclo reprodutivo anual em espécies estacionais; onde são apresentados os períodos de gestação e a forma como se agrupam os nascimentos, independentemente da época reprodutiva da espécie, em vermelho as fêmeas estão apresentando estro ou cio. Fonte: VALENCIA, 2018. -/- -/- Fotoperíodo -/- Para sincronizar o período fértil com a época mais favorável do ano, a maioria das espécies sazonais usa o fotoperíodo (quantidade de luz diária ao longo do ano). -/- Este sinal ambiental é seguro, confiável e se repete a cada ano. Ovinos e caprinos se reproduzem na época do ano em que os dias são curtos e os equinos quando são longos. O grau de sazonalidade depende da origem da raça. As raças nativas de países localizados em latitudes elevadas (> 50°,ovelhas: soay, blackface, suffolk; cabras: saanen, alpino francês, toggenburg; equinos: puro-sangue, hanoveriano) terão uma estacionalidade mais acentuada do que as latitudes menores ou mediterrâneas (ovelhas: merino; cabras: murciana granadina; equinos: quarto de milha). Também existem raças de latitudes próximas ao Equador cuja estacionalidade é baixa ou nula (ovelhas: raças de pelo, crioulas; cabras: raças africanas e asiáticas) (tabela 2). -/- Para a maioria das raças de ovinos e caprinos, a estação reprodutiva começa no final do verão e início do outono; caracteriza-se pela apresentação de ciclos estrais sucessivos, e termina no final do inverno, quando se inicia o anestro, que se caracteriza pela ausência de ovulação. Nos equinos, ocorre o contrário, uma vez que a estação reprodutiva ocorre na primavera e no verão. -/- -/- Tabela 2: Relação entre a origem da raça e o grau de estacionalidade ou sazonalidade -/- Espécie -/- Alta -/- Média -/- Baixa -/- Ovinos -/- Suffolk, raças britânicas de lã e corte -/- Merino -/- Pelibuey, crioulas -/- Caprinos -/- Saanen, alpino, toggenburg -/- Murciana granadina -/- Crioula -/- Equinos -/- Puro-sangue, hanoveriano, quarto de milha -/- - -/- Crioula, burros -/- Fonte: VALENCIA, 2018. -/- -/- Mecanismo neuroendócrino da estacionalidade -/- Durante o período de anestro, o fotoperíodo exerce efeito inibitório sobre o centro tônico do GnRH no hipotálamo, diminuindo a frequência de pulso. Consequentemente, a pulsatilidade do LH também diminui, que agora é incapaz de induzir a maturação folicular, o aumento dos estrogênios, o pico pré-ovulatório de LH e, portanto, a ovulação. -/- Isso ocorre porque durante o anestro a sensibilidade do hipotálamo ao mecanismo de feedback negativo dos estrogênios e de outros fatores de origem não gonodal é aumentada. Ao aproximar-se da estação reprodutiva, a sensibilidade hipotalâmica diminui e o aumento da pulsatilidade do GnRH causa as mudanças que culminam na ovulação. Portanto, o mecanismo endócrino do anestro estacional é semelhante ao do anestro pré-púbere e de alguns outros tipos de anestro. -/- A estacionalidade é um bom exemplo da interação entre o meio ambiente e o sistema neuroendócrino, pois o organismo é capaz de traduzir um sinal externo ambiental, como o fotoperíodo, em um sinal hormonal interno, que neste caso é a melatonina. -/- A glândula pineal secreta melatonina durante as horas de escuridão. Os animais sazonais apresentam um ritmo reprodutivo endógeno, que é regulado por janelas de fotossensibilidade, determinadas por mudanças na duração do dia. O sinal luminoso é captado pela retina e conduzido, via nervo, pelo trato retino-hipotalâmico até o núcleo supraquiasmático, que funciona como o relógio biológico do corpo. Daí o sinal viaja para o núcleo para-ventricular, depois para o gânglio cervical e, finalmente, para a glândula pineal, que responde secretando melatonina (figura 3). -/- Nas ovelhas, a estação reprodutiva começa quando a duração do dia diminui e, naturalmente, a noite aumenta; na égua, ocorre quando os dias se alongam. -/- A primavera não é necessariamente a melhor época do ano em todas as regiões do globo. Nas latitudes tropicais, a primavera coincide com a seca e não com a abundância de forragem, aspecto a ser levado em consideração ao programar a reprodução. -/- Outro ponto importante a considerar é que as raças europeias sazonais mantêm sua estacionalidade no Brasil. -/- -/- Figura 3: Mecanismo do fotoperíodo em ovinos e a melatonina. Fonte: HAFEZ, 2004. -/- -/- Estacionalidade no macho -/- O macho é menos afetado que a fêmea pelas mudanças típicas de cada época do ano, já que sua função reprodutiva não é necessariamente interrompida durante o anestro ou repouso sexual, embora a produção de hormônios reprodutivos, tamanho e tônus testicular, a libido, as características qualitativas e quantitativas do ejaculado e a fertilidade do esperma podem ser diminuídas. O nível de afetação depende do grau de sazonalidade da raça e da latitude. Por fim, os efeitos do fotoperíodo devem ser separados dos nutricionais, que também variam com a época do ano. -/- -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- -/- BEARDEN, Henry Joe et al. Reproducción animal aplicada. México: Manual Moderno, 1982. -/- BROOKS, P. H.; COLE, D. J. A. The effect of the presence of a boar on the attainment of puberty in gilts. Reproduction, v. 23, n. 3, p. 435-440, 1970. -/- CARDOSO, Daniel; DE PAULA NOGUEIRA, Guilherme. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas. Arquivos de Ciências Veterinárias e Zoologia da Unipar, v. 10, n. 1, 2007. -/- CHEMINEAU, P. et al. Induction and persistence of pituitary and ovarian activity in the out-of-season lactating dairy goat after a treatment combining a skeleton photoperiod, melatonin and the male effect. Reproduction, v. 78, n. 2, p. 497-504, 1986. -/- CLARKE, Iain J. et al. Kisspeptin and seasonality in sheep. Peptides, v. 30, n. 1, p. 154-163, 2009. -/- CORTEEL, J. M. Production, storage and insemination of goat semen. In: Management and Reproduction in Sheep and Goats Symposium, Madison, Wis. (USA), 1977. University of Wisconsin, 1977. -/- CUNNINGHAM, James. Tratado de fisiologia veterinária. Elsevier Health Sciences, 2011. -/- CUPPS, Perry T. (Ed.). Reproduction in domestic animals. Elsevier, 1991. -/- DUKES, Henry Hugh; SWENSON, Melvin J.; REECE, William O. Dukes fisiologia dos animais domésticos. Editora Guanabara Koogan, 1996. -/- DÝRMUNDSSON, Ó. R.; LEES, J. L. Effect of rams on the onset of breeding activity in Clun Forest ewe lambs. The Journal of Agricultural Science, v. 79, n. 2, p. 269-271, 1972. -/- EBLING, F. J. P.; FOSTER, D. L. Photoperiod requirements for puberty differ from those for the onset of the adult breeding season in female sheep. Reproduction, v. 84, n. 1, p. 283-293, 1988. -/- FIELDS, Michael J.; SAND, Robert S.; YELICH, Joel V. (Ed.). Factors affecting calf crop: Biotechnology of reproduction. CRC Press, 2001. -/- HAFEZ, Elsayed Saad Eldin; HAFEZ, Bahaa. Reprodução animal. São Paulo: Manole, 2004. -/- HUGHES, P. E.; PHILIP, G.; SISWADI, R. The effects of contact frequency and transport on the efficacy of the boar effect. Animal Reproduction Science, v. 46, n. 1-2, p. 159-165, 1997. -/- KARSCH, FRED J. et al. Neuroendocrine basis of seasonal reproduction. In: Proceedings of the 1983 Laurentian Hormone Conference. Academic Press, 1984. p. 185-232. -/- LINCOLN, G. A.; SHORT, R. V. Seasonal breeding: nature's contraceptive. In: Proceedings of the 1979 Laurentian Hormone Conference. Academic Press, 1980. p. 1-52. -/- MELLO, Raquel Rodrigues Costa. Puberdade e maturidade sexual em touros bovinos. Agropecuária Científica no Semiárido, v. 10, n. 3, p. 11-28, 2015. -/- MEZA‐HERRERA, C. A. et al. Neuroendocrine, metabolic and genomic cues signalling the onset of puberty in females. Reproduction in Domestic Animals, v. 45, n. 6, p. e495-e502, 2010. -/- MONTEIRO, Claudia Dias; BICUDO, Sony Dimas; TOMA, Hugo Shisei. Puberdade em fêmeas ovinas. Pubvet, v. 4, p. Art. 850-857, 2010. -/- OLIVEIRA, Daniel de Jesus Cardoso de. Mecanismos neuroendócrinos envolvidos na puberdade de novilhas da raça Nelore. 2006. Tese de Doutorado em Medicina Veterinária. Universidade de São Paulo. -/- OLSTER, DEBORAH H.; FOSTER, DOUGLAS L. Control of gonadotropin secretion in the male during puberty: a decrease in response to steroid inhibitory feedback in the absence of an increase in steroid-independent drive in the sheep. Endocrinology, v. 118, n. 6, p. 2225-2234, 1986. -/- PIRES, Bruno Carlos et al. Métodos para elevar o ritmo reprodutivo dos ovinos. PUBVET, Londrina, V. 5, N. 11, Ed. 158, Art. 1071, 2011. -/- PLANT, Tony M.; ZELEZNIK, Anthony J. (Ed.). Knobil and Neill's physiology of reproduction. New York: Academic Press, 2014. -/- RAMIREZ, Domingo V.; MCCANN, S. M. Comparison of the regulation of luteinizing hormone (LH) secretion in immature and adult rats. Endocrinology, v. 72, n. 3, p. 452-464, 1963. -/- ROSER, JANET F.; HUGHES, JOHN P. Seasonal effects on seminal quality, plasma hormone concentrations, and GnRH‐induced LH response in fertile and subfertile stallions. Journal of andrology, v. 13, n. 3, p. 214-223, 1992. -/- SALOMONI, Eduardo et al. Idade e peso à puberdade em fêmeas de corte puras e cruzas em campo natural. Pesquisa Agropecuária Brasileira, v. 23, n. 10, p. 1171-1179, 1988. -/- SMITH, Jeremy T.; CLARKE, Iain J. Seasonal breeding as a neuroendocrine model for puberty in sheep. Molecular and cellular endocrinology, v. 324, n. 1-2, p. 102-109, 2010. -/- VALENCIA, J. Pubertad y estacionalidad reproductiva. In. PORTA, L. R.; MEDRANO, J. H. H. Fisiología reproductiva de los animales domésticos. Cidade do México: FMVZ-UNAM, 2018. -/- WHITTEMORE, Colin et al. The science and practice of pig production. Blackwell Science Ltd, 1998. -/- -/- -/- FIXAÇÃO DO ASSUNTO -/- -/- 1. Defina o que é puberdade e como ela manifesta-se no corpo. -/- -/- -/- 2. Diferencie puberdade de maturidade sexual. -/- -/- -/- 3. Quais são os fenômenos que devem ser observados em fêmeas que estão entrando na puberdade? -/- -/- -/- 4. Qual o papel do GnRH e do IGF-I sobre a puberdade? -/- 5. Um produtor possui duas ovelhas e um carneiro reprodutor, as ovelhas possuem idade e peso, mas não manifestaram seu primeiro cio, quais elementos que você recomenda ao produtor para induzir a ciclicidade dessas fêmeas? -/- -/- -/- 6. De forma geral, quais os fatores que podem afetar a entrada na puberdade dos animais? -/- -/- -/- 7. Defina estacionalidade reprodutiva. -/- -/- -/- 8. O que é fotoperíodo e qual sua importância para a reprodução dos animais domésticos? -/- -/- -/- 9. Defina as relações existentes entre a origem da raça e o grau de estacionalidade e como tais teorias se aplicam ao rebanho brasileiro. -/- -/- -/- 10. Qual o papel da glândula pineal para a estacionalidade reprodutiva? -/- -/- -/- 11. Por que os machos são menos afetados pela sazonalidade reprodutiva do que as fêmeas? -/- -/- -/- 12. Sabendo-se sobre os termos de puberdade e estacionalidade e as características de ambos nas espécies domésticas, pede-se: um criador deseja obter 5 novas crias ovinas e 5 caprinas em seu plantel até o final do ano, para tanto ele ainda possui um ano e está na estação do verão, sabendo-se sobre a estacionalidade dessas espécies elabore um projeto reprodutivo de modo que essas 10 fêmeas possam gerar uma cria cada até a primavera. -/- -/- Dados: 10 fêmeas gerando 10 crias. 1 macho ovino e 1 caprino. Fêmeas com 1 ano de idade (2º cio) e peso corporal = 55% do peso adulto. Verão de 2020 para parir na primavera de 2020. (shrink)

This paper examines the idea of "objective phenomenology," or a way of understanding the phenomenal character of conscious experiences that doesn’t require one to have had the kinds of experiences under consideration. My central thesis is that structural facts about experience—facts that characterize purely how conscious experiences are structured—are objective phenomenal facts. I begin by precisifying the idea of objective phenomenology and diagnosing what makes any given phenomenal fact subjective. Then I defend the view that structural facts about experience are (...) objective. I also argue that structural facts about experience, despite being objective, nevertheless still give rise to an explanatory gap. (shrink)

In the science of consciousness, it’s oftentimes assumed that some creatures (or mental states) are more conscious than others. But in recent years, a number of philosophers have argued that the notion of degrees of consciousness is conceptually confused. This paper (1) argues that the most prominent objections to degrees of consciousness are unsustainable, (2) examines the semantics of ‘more conscious than’ expressions, (3) develops an analysis of what it is for a degreed property to count as degrees of consciousness, (...) and (4) applies the analysis to various theories of consciousness. I argue that whether consciousness comes in degrees ultimately depends on which theory of consciousness turns out to be correct. But I also argue that most theories of consciousness entail that consciousness comes in degrees. (shrink)

This paper develops a theory of analog representation. We first argue that the mark of the analog is to be found in the nature of a representational system’s interpretation function, rather than in its vehicles or contents alone. We then develop the rulebound structure theory of analog representation, according to which analog systems are those that use interpretive rules to map syntactic structural features onto semantic structural features. The theory involves three degree-theoretic measures that capture three independent ways in which (...) a system can be more or less analog. We explain how our theory improves upon prior accounts of analog representation, provides plausible diagnoses for novel challenge cases, extends to hybrid systems that are partially analog and partially symbolic, and accounts for some of the advantages and disadvantages of representing analogically versus symbolically. (shrink)

Conscious experiences are characterized by mental qualities, such as those involved in seeing red, feeling pain, or smelling cinnamon. The standard framework for modeling mental qualities represents them via points in geometrical spaces, where distances between points inversely correspond to degrees of phenomenal similarity. This paper argues that the standard framework is structurally inadequate and develops a new framework that is more powerful and flexible. The core problem for the standard framework is that it cannot capture precision structure: for example, (...) consider the phenomenal contrast between seeing an object as crimson in foveal vision versus merely as red in peripheral vision. The solution I favor is to model mental qualities using regions, rather than points. I explain how this seemingly simple formal innovation not only provides a natural way of modeling precision, but also yields a variety of further theoretical fruits: it enables us to formulate novel hypotheses about the space and structures of mental qualities, formally differentiate two dimensions of phenomenal similarity, generate a quantitative model of the phenomenal sorites, and define a measure of discriminatory grain. A noteworthy consequence is that the structure of the mental qualities of conscious experiences is fundamentally different from the structure of the perceptible qualities of external objects. (shrink)

Some philosophers think that life is worth living not merely because of the goods and the bads within it, but also because life itself is good. I explain how this idea can be formalized by associating each version of such of a view with a function from length of life to the value generated by life itself. Then I argue that every version of the view that life itself is good faces some version of the following dilemma: either (1) good (...) human lives are worse than very long lives wholly devoid of pleasure, desire-satisfaction, knowledge, or any other goods, or (2) very short lives containing nothing but suffering are worth living. Since neither result is plausible, we ought to reject the view that life itself is good. On the view I favor, any given life may be worth living because of the goods that it contains, but life itself is neutral. (shrink)

Many philosophers accept both of the following claims: (1) consciousness matters morally, and (2) species membership doesn’t matter morally. In other words, many reject speciesism but accept what we might call 'sentientism'. But do the reasons against speciesism yield analogous reasons against sentientism, just as the reasons against racism and sexism are thought to yield analogous reasons against speciesism? This paper argues that speciesism is disanalogous to sentientism (as well as racism and sexism). I make a case for the following (...) asymmetry: (a) some non-humans clearly have interests, but (b) no non-conscious entities clearly have interests. This asymmetry, I argue, renders sentientism resistant to the standard argument against speciesism. (shrink)

Epistemic injustices are wrongs that agents can suffer in their capacity as knowers. In this article, I offer a conceptualisation of a phenomenon I call anticipatory epistemic injustice, which I claim is a distinct and particularly pernicious type of epistemic injustice worthy of independent analysis. I take anticipatory epistemic injustice to consist in the wrongs that agents can suffer as a result of anticipated challenges in their process of taking up testimony-sharing opportunities. I distinguish my account from paradigmatic cases of (...) epistemic injustice, such as Miranda Fricker’s concepts of testimonial injustice and hermeneutical injustice; additionally, I differentiate my view from Kristie Dotson’s account of testimonial smothering. I argue, ultimately, that anticipatory epistemic injustice is a useful addition to our current taxonomy of epistemic injustices, as it has promising explanatory potential for a range of non-standard cases of epistemic injustice. (shrink)

I discuss whether "sentience" (i.e., phenomenal consciousness) comes in degrees.

Any adequate semantics of generic sentences (e.g., “Philosophers evaluate arguments”) must accommodate both what we call the positive data and the negative data. The positive data consists of observations about what felicitous interpretations of generic sentences are available. Conversely, the negative data consists of observations about which interpretations of generic sentences are unavailable. Nguyen argues that only his pragmatic neo-Gricean account and Sterken’s indexical account can accommodate the positive data. Lee and Nguyen have advanced the debate by arguing that the (...) negative data is a problem for both Nguyen’s and Sterken’s accounts; these two accounts seem to incorrectly predict that generics have felicitous interpretations that they, in fact, fail to have. In this paper, we advance this debate—and, more generally, the task of developing an adequate formal semantics of generics—by arguing that a neglected class of theories are compatible with both the positive data and the negative data. Specifically, we argue that treating the generic operator GEN as a relative gradable expression with a positive, upper- and lower- bounded scale helps accommodate the positive data and the negative data. While developing this view, we show how several previously developed semantics of generics may systematically accommodate both sets of data. One broad contribution of this paper is to show that, while they generate important desiderata, the positive and negative data cannot determine a unique semantics for generics. A further contribution of this paper is to highlight previously unnoted ways in which degree semantics may inform semantic theories of generic meaning. (shrink)

The growing demand for uterus transplantation (UTx) invites continued philosophical evaluation of the function of UTx (and what constitutes its ‘success’), as well as the recipient eligibility for UTx. Currently, UTx caters to partnered, cisgender women of childbearing age looking to get pregnant and give birth to a biogenetically related child. The medical justification for this—the treatment of uterine infertility—explains the primacy of this practice. However, this dominant conceptualization of UTx does not necessarily capture the diverse needs for which both (...) cis‐ and transgender women might take interest in UTx that are not strictly procreative, such as bodily integrity and gender identity reasons. In this paper, I argue that non‐procreative motivations for uterus acquisition ought to be taken seriously as a matter of non‐discrimination and consistency. (shrink)

Henri Lefebvre has considerable claims to be the greatest living philosopher. His work spans some sixty years and includes original work on a diverse range of subjects, from dialectical materialism to architecture, urbanism and the experience of everyday life. The Production of Space is his major philosophical work and its translation has been long awaited by scholars in many different fields. The book is a search for a reconciliation between mental space and real space. In the course of his exploration, (...) Henri Lefebvre moves from metaphysical and ideological considerations of the meaning of space to its experience in the everyday life of home and city. He seeks, in other words, to bridge the gap between the realms of theory and practice, between the mental and the social, and between philosophy and reality. In doing so, he ranges through art, literature, architecture and economics, and further provides a powerful antidote to the sterile and obfuscatory methods and theories characteristic of much recent continental philosophy. This is a work of great vision and incisiveness. It is also characterized by its author's wit and by anecdote, as well as by a deftness of style which Donald Nicholson-Smith's sensitive translation precisely captures. (shrink)

Some have claimed that moral bioenhancement undermines freedom and authenticity – thereby making moral bioenhancement problematic or undesirable – whereas others have said that moral bioenhancement does not undermine freedom and authenticity – thereby salvaging its ethical permissibility. These debates are characterized by a couple of features. First, a positive relationship is assumed to hold between these agency-related concepts and the ethical permissibility of moral bioenhancement. Second, these debates are centered around individualistic conceptions of agency, like free choice and authenticity, (...) which hail from an atomistic tradition of autonomy. My view is that emphasizing individualistic conceptions of autonomy do not provide particularly strong foundations on which to argue about the issue of the permissibility of moral bioenhancement. This is because individualistic autonomy is not the kind of agency-related consideration we ought to value. Instead, I propose that we investigate the relationship between moral bioenhancement and a more relational kind of autonomy. Focusing on this latter relationship, on my view, clarifies the potential for moral bioenhancement to support or enhance people’s autonomy. (shrink)

A response to a declaration in 'Le Monde', 'Luttons efficacement contre les théories du complot' by Gérald Bronner, Véronique Campion-Vincent, Sylvain Delouvée, Sebastian Dieguez, Karen Douglas, Nicolas Gauvrit, Anthony Lantian, and Pascal Wagner-Egger, published on June the 6th, 2016.

I sketch here an intuitive picture of repeatable artworks as created types, which are individuated in part by historical paths (re)production. Although attractive, this view has been rejected by a number of authors on the basis of general claims about abstract objects. On consideration, however, these general claims are overgeneralizations, which whilst true of some abstracta, are not true of all abstract objects, and in particular, are not true of created types. The intuitive picture of repeatable artworks as created types (...) is, then, left in place. (shrink)

Are a material object, such as a statue, and its constituting matter, the clay, parts of one another? One wouldn't have thought so, and yet a number of philosophers have argued that they are. I review the arguments for this surprising claim showing how they all fail. I then consider two arguments against the view concluding that there are both pre-theoretical and theoretical considerations for denying that the statue and the clay are mutual parts.

Literature on testimonial injustice and ways that perpetrators might combat it have flourished since Miranda Fricker’s ground-breaking work on testimonial injustice. Less attention has been given, however, to the role of bystanders. In this paper, I examine the accountability that bystanders may have for their omissions to redress testimonial injustice. I argue that bystander accountability applies in cases where it is opportune for bystanders to intervene, and if they are also sufficiently equipped and able to redress the testimonial injustice. Moreover, (...) I recommend that we move beyond virtue responsibilism for ameliorative thinking about testimonial injustice. (shrink)

Are counterfactuals with true antecedents and consequents automatically true? That is, is Conjunction Conditionalization: if (X & Y), then (X > Y) valid? Stalnaker and Lewis think so, but many others disagree. We note here that the extant arguments for Conjunction Conditionalization are unpersuasive, before presenting a family of more compelling arguments. These arguments rely on some standard theorems of the logic of counterfactuals as well as a plausible and popular semantic claim about certain semifactuals. Denying Conjunction Conditionalization, then, requires (...) rejecting other aspects of the standard logic of counterfactuals, or else our intuitive picture of semifactuals. (shrink)

The standard semantics for counterfactuals ensures that any counterfactual with a true antecedent and true consequent is itself true. There have been many recent attempts to amend the standard semantics to avoid this result. I show that these proposals invalidate a number of further principles of the standard logic of counterfactuals. The case against the automatic truth of counterfactuals with true components does not extend to these further principles, however, so it is not clear that rejecting the latter should be (...) a consequence of rejecting the former. Instead I consider how one might defuse putative counterexamples to the truth of true-true counterfactuals. (shrink)

Is A & C sufficient for the truth of ‘if A were the case, C would be the case’? Jonathan Bennett thinks not, although the counterexample he gives is inconsistent with his own account of counterfactuals. In any case, I argue that anyone who accepts the case of Morgenbesser's coin, as Bennett does, should reject Bennett’s counterexample. Moreover, I show that the principle underlying his counterexample is unmotivated and indeed false. More generally, I argue that Morgenbesser’s coin commits us to (...) the sufficiency of A & C for the truth of the corresponding counterfactual. (shrink)

We start with an observation about implicit quantifier domain restriction: certain implicit restrictions (e.g., restricting objects by location and time) appear to be more natural and widely available than others (e.g., restricting objects by color, aesthetic, or historical properties). Our aim is to explain why this is. That is, we aim to explain why some implicit domain restriction possibilities are available by default. We argue that, regardless of their other explanatory virtues, extant pragmatic and metasemantic frameworks leave this question unanswered. (...) We then motivate a partially nativist account of domain restriction that involves a minimal view of joint planning around broad shared goals about navigating and influencing our environments augmented with cognitive heuristics that facilitate these. Finally, we sketch how the view can be extended to account for the ways non-default restriction possibilities become available when conversationalists have shared idiosyncratic goals. (shrink)

The debate over Hypothetical Syllogism is locked in stalemate. Although putative natural language counterexamples to Hypothetical Syllogism abound, many philosophers defend Hypothetical Syllogism, arguing that the alleged counterexamples involve an illicit shift in context. The proper lesson to draw from the putative counterexamples, they argue, is that natural language conditionals are context-sensitive conditionals which obey Hypothetical Syllogism. In order to make progress on the issue, I consider and improve upon Morreau’s proof of the invalidity of Hypothetical Syllogism. The improved proof (...) relies upon the semantic claim that conditionals with antecedents irrelevant to the obtaining of an already true consequent are themselves true. Moreover, this semantic insight allows us to provide compelling counterexamples to Hypothetical Syllogism that are resistant to the usual contextualist response. (shrink)

I present and discuss a counterexample to Kendall Walton's necessary condition for fictionality that arises from considering serial fictions. I argue that although Walton has not in fact provided a necessary condition for fictionality, a more complex version of Walton's condition is immune from the counterexample.

Moti Mizrahi (2013) presents some novel counterexamples to Hypothetical Syllogism (HS) for indicative conditionals. I show that they are not compelling as they neglect the complicated ways in which conditionals and modals interact. I then briefly outline why HS should nevertheless be rejected.

I reply to Ahmed’s rejection (2011) of my argument (Walters 2009) that all counterfactuals with true antecedents and consequents are themselves true.

It is becoming more common that the decision-makers in private and public institutions are predictive algorithmic systems, not humans. This article argues that relying on algorithmic systems is procedurally unjust in contexts involving background conditions of structural injustice. Under such nonideal conditions, algorithmic systems, if left to their own devices, cannot meet a necessary condition of procedural justice, because they fail to provide a sufficiently nuanced model of which cases count as relevantly similar. Resolving this problem requires deliberative capacities uniquely (...) available to human agents. After exploring the limitations of existing formal algorithmic fairness strategies, the article argues that procedural justice requires that human agents relying wholly or in part on algorithmic systems proceed with caution: by avoiding doxastic negligence about algorithmic outputs, by exercising deliberative capacities when making similarity judgments, and by suspending belief and gathering additional information in light of higher-order uncertainty. (shrink)

Andrew McGonigal presents some interesting data concerning truth in serial fictions.1 Such data has been taken by McGonigal, Cameron and Caplan to motivate some form of contextualism or relativism. I argue, however, that many of these approaches are problematic, and that all are under-motivated as the data can be explained in a standard invariantist semantic framework given some independently plausible principles.

In this paper, I propose a new self-defense theory of punishment, the rights-protection theory. By appealing to the interest theory of right, I show that what we call “the right of self-defense” is actually composed of the right to protect our basic rights. The right of self-defense is not a single, self-standing right but a group of derivative rights justified by their contribution to the protection of the core, basic rights. Thus, these rights of self-defense are both justified and constrained (...) by the basic rights they are supposed to protect. I then explain how this theory responds to a common objection. Opponents argue that, to exercise the right of self-defense, some threat must be present. However, in the context of punishment, the threat has already taken effect or is already gone. Thus, the right of self-defense becomes irrelevant when we punish an offender. I show that this objection is based on an implausibly narrow conception of self-defense. A reasonable conception would allow us to exercise our right of self-defense when there is a present definite threat, a future definite threat, or a potential threat. Thus, we may still exercise our right of self-defense in the context of punishment. (shrink)

ABSTRACT Our ascriptions of content to past utterances assign to them a level of conceptual continuity and determinacy that extends beyond what could be grounded in the usage up to their time of utterance. If one accepts such ascriptions, one can argue either that future use must be added to the grounding base, or that such cases show that meaning is not, ultimately, grounded in use. The following will defend the first option as the more promising of the two, though (...) this ultimately requires understanding the relation between use and meaning as ‘normative’ in two important ways. The first way is that the function from use to meaning must be of a sort that allows us to maintain a robust distinction between actual and correct use. The second sort of normativity is unique to theories that extend the grounding base into the future. In particular, if meaning is partially a function of future use, we can see our commitment to the ‘determinacy’ of meaning as a practical commitment that structures our linguistic practices rather than a theoretical commitment that merely describes them. (shrink)

When performing a skilled action—whether something impressive like a double somersault or something mundane like reaching for a glass of water—you exercise control over your bodily movements. Specifically, you guide their course. In what does that control consist? In this dissertation, I argue that it consists in attending to what you are doing. More specifically, in attending, agents harness their perceptual and perceptuomotor states directly and practically in service of their goals and, in doing so, settle the fine-grained manner in (...) which their bodies will move—details an intention alone leaves unsettled. This requires, among other things, that we reject views on which agents’ control is identical with their practical rationality. When all goes well, agents attentionally prioritize what is motivationally relevant to them to the exclusion of what would otherwise distract them from achieving their goals. However, sometimes agents attend distractedly—i.e., without prioritizing. As the aim of attention is to avoid distraction, this entails the possibility of defective attention. Defective attention, in turn, casts light on scenarios in which agents lose control over what they are doing, as when a skilled practitioner ‘chokes under pressure’. A complaint sometimes levelled against accounts, like mine, that claim to reduce agents’ control of their behaviour to that of causally efficacious mental states or events is that these accounts invariably deprive agents themselves of their rightful role in the generation of behaviour. This is the “Disappearing Agent Problem” for “reductive” or “event-causal” theories of action. I argue that, correctly understood, extant reductive theories do face a genuine Disappearing Agent Problem. However, it is a problem we solve by recognizing the role that conscious attention plays in making an action the agent’s own. Accordingly, I develop and defend an attentional account of action ownership. On this view, allocating conscious attention in service of your goals is sufficient for a kind of conscious perspective (“motivational perspective”), which, when active in controlling your behaviour, constitutes the behaviour as your own doing. As I explain, such perspective also contributes to explaining the subjective structure of your perceptual awareness of the world around you. (shrink)

In light of recent breakneck pace in machine learning, questions about whether near-future artificial systems might be conscious and possess moral status are increasingly pressing. This paper argues that as matters stand these debates lack any clear criteria for resolution via the science of consciousness. Instead, insofar as they are settled at all, it is likely to be via shifts in public attitudes brought about by the increasingly close relationships between humans and AI users. Section 1 of the paper I (...) briefly lays out the current state of the science of consciousness and its limitations insofar as these pertain to machine consciousness, and claims that there are no obvious consensus frameworks to inform public opinion on AI consciousness. Section 2 examines the rise of conversational chatbots or Social AI, and argues that in many cases, these elicit strong and sincere attributions of consciousness, mentality, and moral status from users, a trend likely to become more widespread. Section 3 presents an inconsistent triad for theories that attempt to link consciousness, behaviour, and moral status, noting that the trends in Social AI systems will likely make the inconsistency of these three premises more pressing. Finally, Section 4 presents some limited suggestions for how consciousness and AI research communities should respond to the gap between expert opinion and folk judgment. (shrink)

Totalitarianism is perhaps unanimously regarded as one of the greatest political evils of the last century and has been the grounds for much of Anglo-American political theory since. Confucianism, meanwhile, has been gaining credibility in the past decades among sympathizers of democratic theory in spite of criticisms of it being anti-democratic or authoritarian. I consider how certain key concepts in the classical Confucian texts of the Mencius and the Xunzi might or might not be appropriated for ‘legitimising’ totalitarian regimes. Under (...) an Arendtian approach to understanding totalitarianism, it is precisely an unproblematised relation to a normative History and Nature that underlies the potential compatibility or incompatibility. I argue against a longstanding prejudice that if any form of Confucianism would be totalitarian, it would have to be Xunzian. Against this, I hope to show that if any form of Confucianism would be totalitarian, it might well be a naturalistic Mencian Confucianism instead of a constructivist Xunzian one. (shrink)

The aim of this essay is to introduce an original and radical phenomenology of life into Heidegger’s earliest lectures at Freiburg University. The motivation behind this aim lies in the exclusion of life from the existential analytic despite Heidegger’s preoccupation with the question of life during this very early period. Principally, the essay demonstrates how Husserl’s phenomenological insight into the intentionality of life has the potential to be transformed into a living aporia. Although this demonstration is set within the general (...) context of obtaining knowledge in and of life, it is achieved via a reciprocal critique of the possibility of a philosophy of life and Husserlian phenomenology to reveal the congruence life philosophy has with the project of phenomenology. In contrast to fundamental ontology, the essay ends by exposing Heidegger’s latent and inexplicit formulation of phenomenology in terms of a radical correlation that holds aporetically between living and unliving experience. (shrink)

A picture of the world as chiefly one of discrete objects, distributed in space and time, has sometimes seemed compelling. It is however one of the main targets of Henry Laycock's book; for it is seriously incomplete. The picture, he argues, leaves no space for "stuff" like air and water. With discrete objects, we may always ask "how many?," but with stuff the question has to be "how much?" Laycock's fascinating exploration also addresses key logical and linguistic questions about (...) the way we categorize the many and the much. (shrink)

It is often suggested that when opinions differ among individuals in a group, the opinions should be aggregated to form a compromise. This paper compares two approaches to aggregating opinions, linear pooling and what I call opinion agglomeration. In evaluating both strategies, I propose a pragmatic criterion, No Regrets, entailing that an aggregation strategy should prevent groups from buying and selling bets on events at prices regretted by their members. I show that only opinion agglomeration is able to satisfy the (...) demand. I then proceed to give normative and empirical arguments in support of the pragmatic criterion for opinion aggregation, and that ultimately favor opinion agglomeration. (shrink)

In his Wittgenstein on Rules and Private Language, Saul Kripke famously raised two sorts of problems for responses to the meaning skeptic that appealed to how we were disposed to use our words in the past. The first related to the fact that our “dispositions extend to only finitely many cases” while the second related to the fact that most of us have “dispositions to make mistakes.” The second of these problems has produced an enormous, and still growing, literature on (...) the purported ‘normativity’ of meaning, but the first has received (at least comparatively) little attention. It will be argued here, however, that (1) the fact that we can be disposed to make mistakes doesn’t present a serious problem for many disposition-based responses to the skeptic, and (2) considerations of the ‘finiteness’ of our dispositions point, on their own, to an important way that the relation between meaning and use must be understood as ‘normative’. In particular, the assumption that words have determinate meanings, more so than the assumption that they have ‘correctness’ conditions, rules out the possibility of understanding the relation between meaning and use in the more descriptive fashion commonly associated with dispositionalism. Nevertheless, if the relation of meaning and use is understood in a more normative key, responding to the meaning-skeptic with facts about one’s dispositions will turn out to be perfectly legitimate, though it will prevent one from being the sort of ‘dispositionalist’ that Kripke gives, without any real argument, a monopoly on disposition-based responses. (shrink)

This paper presents an overview of the risks and benefits of Social AI, understood as conversational AI systems that cater to human social needs like romance, companionship, or entertainment. Section 1 of the paper provides a brief history of conversational AI systems and introduces conceptual distinctions to help distinguish varieties of Social AI and pathways to their deployment. Section 2 of the paper adds further context via a brief discussion of anthropomorphism and its relevance to assessment of human-chatbot relationships. Section (...) 3 of the paper provides a survey of potential and in some cases demonstrated harms associated with user interactions with Social AI systems. Finally, Section 4 discusses how the benefits and harms of Social AI can best be addressed, with a primary focus on how frameworks from AI ethics can inform their development. (shrink)

This paper argues that phenomenal consciousness is what makes an entity a welfare subject. I develop a variety of motivations for this view, and then defend it from objections concerning death, non-conscious entities that have interests (such as plants), and conscious entities that necessarily have welfare level zero. I also explain how my theory of welfare subjects relates to experientialist and anti-experientialist theories of welfare goods.

Those sympathetic to the naturalistic side of James hope that his critique of ‘philosophical materialism’ can be separated from those elements of his thinking that are essential to his pragmatism. Such a separation is possible once we see that James’s critique of materialism grows out of his views about its incompatibility with the existence of objective values. Objective values (as James understands them) are incompatible, however, not with materialism in its most general form, but rather with materialism that understood the (...) ‘material world’ in terms of the sciences of the late nineteen hundreds. In particular, one could not defend the potential objectivity of value in the way that James hoped if one endorsed the particular ‘pessimistic’ cosmology characteristic of the sciences at the turn of the last century. Consequently, if one rejects certain ‘empirical assumptions’ associated with the science of James’s day, the possibility of a type of ‘melioristic materialism’ opens up, and this sort of materialist could still understand value in the way that James proposes. (shrink)

The philosophy of biomimicry, I argue, consists of four main areas of inquiry. The first, which has already been explored by Freya Mathews, concerns the “deep” question of what Nature ultimately is. The second, third, and fourth areas correspond to the three basic principles of biomimicry as laid out by Janine Benyus. “Nature as model” is the poetic principle of biomimicry, for it tells us how it is that things are to be “brought forth”. “Nature as measure” is the ethical (...) principle of biomimicry, for it tells us that Nature places ethical limits or standards on what it is possible for us to accomplish. And “Nature as mentor” is the epistemological principle of biomimicry, for it affirms that Nature is the ultimate source of truth, wisdom, and freedom from error. Within this overall framework, I argue that seeing Nature as physis—understood as “self-production” or “self-placing-into-the-open”—constitutes the requisite ground for the poetic, ethical, and epistemological principles of biomimicry, and that biomimicry thus conceived involves a new philosophical paradigm, which I call “enlightened naturalism”. (shrink)

This paper explores two ideas in Aristotle: the idea that a just person is necessarily a lawful and law-abiding citizen, and second, the idea that the virtuous person necessarily cares about the common good. In this paper, I show that justice and its concern for the common good is central to Aristotle’s conception of the virtuous agent, and that justice, in turn, cannot be understood apart from the various laws that states devise for the common benefit.

Ascriptions of content are sensitive not only to our physical and social environment, but also to unforeseeable developments in the subsequent usage of our terms. This paper argues that the problems that may seem to come from endorsing such 'temporally sensitive' ascriptions either already follow from accepting the socially and historically sensitive ascriptions Burge and Kripke appeal to, or disappear when the view is developed in detail. If one accepts that one's society's past and current usage contributes to what one's (...) terms mean, there is little reason not to let its future usage to do so as well. (shrink)

In his theory of determination, Charles Peirce considered two processes of determination, the semiotic process and epistemology. The semiotic process is an extensional process from object to interpretant that consists of an infinite chain of references that can be spatially reversible. The epistemological process of determination is temporal and irreversible, where the idea grows into the individual mind, as the universe is unfolded by the agency of mind.

The close association of particular races with particular classes invites a means to exhibit disdain for a race via class. Class and race do not simply occupy a list of social problems, because generally, specific races correlate with particular classes. Racism is presently unacceptable, but not classism. We may feel sympathy for the poor, but we do not refrain from disdain. The disdain of the poor centers on Neoclassical economics’ insistence on choice in regards to class. The language of choice (...) does not circumscribe race. Michel Foucault’s work illustrates that the persistent correlation of race and class is not merely sociological but conceptual. Such close associations of particular races with particular classes serve as a means to generate essentialisms that express racism through classism. (shrink)

We propose an approach to the question of how qualia fit into the physical world, in the context of a relational and realist completion of quantum theory, called the causal theory of views\cite{views}. This is a combination of an approach to a dynamics of discrete causal structures, called energetic causal sets, developed with M. Cortes, with a realist approach to quantum foundations, called the real ensemble formulation. In this theory, the beables are the information available at each event from its (...) causal past, such as its causal predessesors and the energy and momentum they transfer to the event. We call this the view of an event. That is, we describe a causal universe that is composed of a set of partial views of itself. We propose that conscious perceptions are aspects of some views. This addresses the problem of why consciousness always involves awareness of a bundled grouping of qualia that define a momentary self. This gives a restricted form of panpsychism defined by a physically based selection principle which selects which views have experiential aspects. We further propose that only those views which are novel, in the sense that they are not duplicates of the view of any event in the event's own causal past, are the physical correlates of conscious experience. (shrink)

I introduce game-theoretic models for threats to the discussion of threats in speech act theory. I first distinguish three categories of verbal threats: conditional threats, categorical threats, and covert threats. I establish that all categories of threats can be characterized in terms of an underlying conditional structure. I argue that the aim—or illocutionary point—of a threat is to change the conditions under which an agent makes decisions in a game. Threats are moves in a game that instantiate a subgame in (...) which the addressee is ‘under threat’. (shrink)