The study's general objective is to determine the students' stance on the most appropriate model of writing skills, using Structural Equation Modeling (SEM) as a basic design in the relationship of self-regulated learning strategies, communicative learning strategies, learning grammatical strategies, and writing skills. This study used a mixed-method sequential explanatory design, in which quantitative design is more widely used than qualitative Creswell, J., & Creswell, D. (2017). The researcher used the stratified random sampling technique for selecting respondents and, by using (...) the Raosoft sample size calculator, identified 390 respondents using a four-part questionnaire to collect data. Purposive sampling is the method for determining participants in a qualitative design using a guided questionnaire to obtain data from In-Depth Interviews and Focus Group Discussions. Model 5 was the best-fitting model for writing skills, showing significant correlations with the exogenous variables: self-regulated learning strategies, communicative learning strategies, learning grammatical strategies, and writing skills as endogenous variables. Both the exogenous and endogenous variables obtained a high level of overall description, meaning that students often practiced strategies to cultivate writing skills. The participants' stance on the most appropriate model is essential for tertiary students to have different strategies for developing writing skills. It is necessary to reach the full description of the highest level by using different strategies to build writing skills. (shrink)

Reading tough books to achieve excellent marks, perform well in class, and gain attention from teachers and parents is less likely to drive students. Students used to evaluate their language learning requirements, define the abilities they wished to develop, pick effective study techniques, and set aside gadgets when studying. They also used to read the question before looking for hints in the relevant content, extract the essential lines that convey the major ideas, concentrate on titles, names, numbers, quotations, or instances, (...) and comprehend the overall context to infer an option. The survey discovered that most of the time, students utilized it to determine the progress of their learning and create learning objectives. It was also found that there was a link between the exogenous variables and the academic performance of students. (shrink)

Sustainability science seeks to extend scientific investigation into domains characterized by a distinct problem-solving agenda, physical and social complexity, and complex moral and ethical landscapes. In this endeavor it arguably pushes scientific investigation beyond its usual comfort zones, raising fundamental issues about how best to structure such investigation. Philosophers of science have long scrutinized the structure of science and scientific practices, and the conditions under which they operate effectively. We propose a critical engagement between sustainability scientists and philosophers of science (...) with respect to how to engage in scientific activity in these complex domains. We identify specific issues philosophers of science raise concerning current sustainability science and the contributions philosophers can make to resolving them. In conclusion we reflect on the steps philosophers of science could take to advance sustainability science. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

There is a paucity of research on how psychopathy relates to decision-making. In this study, we assessed the relationship between affective decision-making and psychopathic personality. A sample of prisoners (n D 49) was characterized in terms of psychopathic traits using the Psychopathic Checklist: Screening Version (PCL:SV). Decision-making was assessed using the Iowa Gambling Task (IGT). Higher levels of psychopathy related to more advantageous choices (p D .003). Also counter-intuitively, higher levels of antisocial traits (facet 4) predicted advantageous choices during the (...) learning phase of the task (p D .004). Our findings suggest that some psychopathic facets may be more relevant to decisionmaking under risk, and highlight the importance of further investigations considering facet and trait-level relationships with decision-making. (shrink)

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Until recently, psychologists have conceptualised and studied trust in God (TIG) largely in isolation from contemporary work in theology, philosophy, history, and biblical studies that has examined the topic with increasing clarity. In this article, we first review the primary ways that psychologists have conceptualised and measured TIG. Then, we draw on conceptualizations of TIG outside the psychology of religion to provide a conceptual map for how TIG might be related to theorised predictors and outcomes. Finally, we provide a research (...) agenda for future empirical work in this area, as well as practical applications for counsellors and religious leaders. (shrink)

Subjectivists about welfare face two problems that pull them in opposite directions. The Paradox Problem, outlined by Ben Bradley, is that, for an agent who desires that her life go badly, subjectivist theories are sometimes unable to give a determinate answer about how well her life goes. This problem demands that subjectivists choose a complex mental attitude to ground well-being. The Infant Problem, from Eden Lin, is that many subjective theories end up denying that infants (and some others) have welfare. (...) This problem demands that subjectivists choose a simple attitude to ground well-being. I argue that subjectivists should respond by adopting Disjunctive Subjectivism. Your welfare depends on your judgements that things are intrinsically good or bad for you (c.f. Dorsey), unless you are not capable of such judgements. In that case, it depends on your desires. I then defend DS against objections from Lin, and the potential charge of being ad hoc. (shrink)

This paper explores some connections between depictions of mortality in portrait-painting and philosophical (and psychoanalytic) treatments of our need to be recognized by others. I begin by examining the connection that Georg Simmel makes in his philosophical study of Rembrandt between that artist’s capacity for depicting his portrait subjects as non-repeatable individuals and his depicting them as mortal, or such as to die. After noting that none of Simmel’s explanations of the tragic character of Rembrandt’s portrait subjects seems fully satisfactory, (...) I then turn to Rousseau’s writing on our need for the recognition of others in order to argue that (1) it is at least as sources for the satisfaction of this need that other persons figure for us as irreplaceable (in a way that contrasts with the kinds of satisfaction that intersubstitutable things afford us); and that (2) it is exactly this kind of irreplaceability that Simmel is gesturing at in connecting the concepts of individuality and mortality in his writing on Rembrandt’s portraits. For the remainder of the paper I argue that the foregoing ideas are in fact central to the psychoanalytic writing of Melanie Klein, and in particular (a) Klein’s understanding the infant’s apprehension of other persons as internally related to their anxieties about the possibility of those persons’ irretrievable loss; (b) her understanding that it is as sources of recognition that others’ personhood is made salient to us; and (c) her treatment of portrait-painting as an activity for working through those aforementioned anxieties. (shrink)

C. Stephen Layman contends that an argument supporting theism over naturalism can be constructed based on three defensible, non–question-begging premises about the moral order. Previous critics of Layman’s argument have challenged the truth of these premises. We stipulate them arguendo but go on to show that there is a deeper problem: a fourth premise introduced to complete the argument—the “completion premise,” as we call it—is true only if we assume that God exists or we concede that there is no afterlife. (...) We close with suggestions for how Layman’s argument must be strengthened to meet with dialectical success. (shrink)

In this chapter, I attempt to show that evil exists only if what I call Agent Causal Theism (ACT) is true. According to ACT, human beings are immaterial, conscious agents endued (by God) with a power of self-motion: the power to think, decide, and act for ends in light of reasons, but without being externally caused to do so (even by God himself). By contrast, I argue that there is no space for evil in the worldviews of naturalistic Darwinism or (...) theistic Calvinism. (shrink)

S. C. Gibb holds that some mental events enable physical events to take place by acting as ‘double preventers’ which prevent other mental events from effecting change in the physical domain. She argues that this enables a dualist account of psychophysical interaction consistent with the causal relevance of mental events, their distinctness from physical events, the causal closure of the physical and the exclusion of systematic overdetermination. While accepting the causal powers metaphysic, this paper argues that: Closure is maintained only (...) on the assumption of an implausible pre-ordained harmony between preventing and double-preventing mental events. Distinctness is preserved only at the cost of positing brute unexplained powers of mental and physical events to causally interact with each other. Exclusion is systematically violated in a substantial number of everyday cases. The case for Relevance made by the Double Prevention model is accordingly too weak to sustain a dualist approach to mental causation. (shrink)

I present Aristotle’s theory of causation in a way that privileges a comparison with contemporary discussion on causation. I do so by selecting in Aristotle’s theory points that are interesting to contemporary discussion and by translating Aristotle in the contemporary philosophical terminology. I compare Aristotle’s views with Mackie’s (1993/1965) and Sosa’s (1993/1980). Mackie is a humean regularist regarding the metaphysics of causal necessity, but his theory postulates some formal aspects of the causal relation which are similar to the Aristotelian theory. (...) By introducing the notion of causal field as a third causal relatum – a sample in which the cause must be picked out as a explanation coextensive to the effect –, Mackie holds a point very similar to Aristotle, inasmuch as both defend that the causal relation is triadic and both have the extensional desideratum. Sosa (1993/1980) defends that every cause necessitates its effect, arguing against classical Humeanism, and he also proposes a causal pluralism. Both these theses are clearly Aristotelian. Aristotle comprehends that the causal relation has three relata: a subjacent C, a property of that subjacent A and a cause B that explains why such property is attributed to that subjacent. The subjacent is similar to Mackie’s notion of causal field, for in regard to it the cause must be coextensive to the property. But Aristotle also says that for each explanandum (property attributed to a subjacent of which one aims to investigate a cause) there is only one cause, which necessitates it. Sosa and Aristotle are similar because both develop a causal pluralism from a theory of causes as having intrinsic necessitation. For Aristotle, causes/explanations [aitiai] are central for attaining scientific knowledge, and its triadic structure determines the syllogistic structure of scientific demonstrations. Aristotle’s theory of causation also involves comprehending the actualisation of capacities (dispositional properties of objects) affirming that the causal relation is resultant from intrinsic properties of the objects, and the cause B is the essence of the explanandum. (shrink)

It is my goal in this paper to offer a strategy for translating universal statements about utopia into particular statements. This is accomplished by drawing out their implicit, temporally embedded, points of reference. Universal statements of the kind I find troublesome are those of the form ‘Utopia is x’, where ‘x’ can be anything from ‘the receding horizon’ to ‘the nation of the virtuous’. To such statements, I want to put the questions: ‘Which utopias?’; ‘In what sense?’; and ‘When was (...) that, is that, or will that be, the case for utopias?’ Through an exploration of these lines of questioning, I arrive at three archetypes of utopian theorizing which serve to provide the answers: namely, utopian historicism, utopian presentism, and utopian futurism. The employment of these archetypes temporally grounds statements about utopia in the past, present, or future, and thus forces discussion of discrete particulars instead of abstract universals with no meaningful referents. (shrink)

WILLIAM DAVIS HAS MAINTAINED THAT A SUPER PLEASURE HELMET COULD IN PRINCIPLE SATISFY ALL HUMAN NEEDS, BUT THAT SUCH A MACHINE IS PROBABLY A PRACTICAL IMPOSSIBILITY. I ARGUE THAT THE SUPER PLEASURE HELMET IS CONCEPTUALLY IMPOSSIBLE BY ARGUING THAT A PERSON'S NEEDS CANNOT BE SATISFIED JUST BY BRINGING ABOUT CERTAIN PSYCHOLOGICAL STATES IN THAT PERSON.

Revista IT & C este o publicație trimestrială din domeniile tehnologiei informației și comunicații, și domenii conexe de studiu și practică. -/- Cuprins: -/- EDITORIAL Cu sau fără Internet?, de Nicolae Sfetcu -/- TEHNOLOGIA INFORMAȚIEI Tehnologia blockchain, de Nicolae Sfetcu -/- TELECOMUNICAȚII Rețelele de comunicații 5G, de Nicolae Sfetcu -/- INTERNET Megadatele (Big Data) pe Internet, de Nicolae Sfetcu -/- SOFTWARE Excel: Comenzi rapide și formatare de bază, de Nicolae Sfetcu -/- PROGRAMARE Tipuri de date atomice în Python, de Stephen (...) Davies -/- DEZVOLTARE WEB Variabile în dezvoltarea WordPress, de Nicolae Sfetcu -/- SECURITATE CIBERNETICĂ Securitatea Big Data: Amenințări, de Nicolae Sfetcu -/- AFACERI ONLINE Marketing de conţinut, de Nicolae Sfetcu -/- MEDIA Cercetare și aplicații în rețelele sociale, de Bogdan Batrinca și Philip C Treleaven -/- ISSN 2821– 8469 ISSN – L 2821 – 8469, DOI: 10.58679/IT35986. (shrink)

Revista IT & C este o publicație trimestrială din domeniile tehnologiei informației și comunicații, și domenii conexe de studiu și practică. -/- Cuprins: -/- EDITORIAL Cu sau fără Internet?, de Nicolae Sfetcu Supremația tehnologiilor IT&C, de Nicolae Sfetcu -/- TEHNOLOGIA INFORMAȚIEI Tehnologia blockchain, de Nicolae Sfetcu Ciclul de viață al inteligenței artificiale, de Nicolae Sfetcu -/- TELECOMUNICAȚII Rețelele de comunicații 5G, de Nicolae Sfetcu Proiectarea și arhitectura rețelelor de comunicații 5G, de Nicolae Sfetcu -/- INTERNET Megadatele (Big Data) pe Internet, (...) de Nicolae Sfetcu Cum funcționează Internetul, de Michael Mendez -/- SOFTWARE Deschideți / Creați o imagine în Adobe Photoshop, de Nicolae Sfetcu Excel: Comenzi rapide și formatare de bază, de Nicolae Sfetcu -/- PROGRAMARE Utilizarea limbajului de programare R în știința datelor cu RStudio, de Rafael A. Irizarry Tipuri de date atomice în Python, de Stephen Davies -/- DEZVOLTARE WEB Servere web, de Michael Mendez Variabile în dezvoltarea WordPress, de Nicolae Sfetcu -/- SECURITATE CIBERNETICĂ Securitatea informațiilor în lucrul cu megadate pe Internet, de Nicolae Sfetcu Securitatea Big Data: Amenințări, de Nicolae Sfetcu -/- AFACERI ONLINE Proiectarea și modelarea tehnologiei blockchain – Bitcoin, de Nicolae Sfetcu Marketing de conţinut, de Nicolae Sfetcu -/- MEDIA Analitica rețelelor sociale, de Nicolae Sfetcu Cercetare și aplicații în rețelele sociale, de Bogdan Batrinca și Philip C Treleaven -/- ISSN 2971 – 9097 ISSN-L 2821 – 8469, DOI: 10.58679/IT89910. (shrink)

Review of *New Essays on the A Priori*, an excellent collection edited by Paul Boghossian and Christopher Peacocke. Contributors include: Tyler Burge; Quassim Cassam; Philip Kitcher; Penelope Maddy; Hartry Field; Paul Horwich; Peter Railton; Stephen Yablo; Bob Hale; Crispin Wright; Frank Jackson; Stewart Shapiro; Michael Friedman; Martin Davies; Bill Brewer; and Thomas Nagel.

Chapter 1: "Reason for Hope " by Michael J. Murray Chapter 2: "Theistic Arguments" by William C. Davis Chapter 3: "A Scientific Argument for the Existence of God: The Fine- Tuning Design Argument" by Robin Collins Chapter 4: "God, Evil and Suffering" by Daniel Howard Snyder Chapter 5: "Arguments for Atheism" by John O'Leary Hawthorne Chapter 6: "Faith and Reason" by Caleb Miller Chapter 7: "Religious Pluralism" by Timothy O'Connor Chapter 8: "Eastern Religions" by Robin Collins Chapter 9: "Divine (...) Providence and Human Freedom" by Scott A. Davison Chapter 10: "The Incarnation and the Trinity" by Thomas D. Senor Chapter 11: "The Resurrection of the Body and the Life Everlasting" by Trenton Merricks Chapter 12: "Heaven and Hell" by Michael J. Murray Chapter 13: "Religion and Science" by W. Christopher Stewart Chapter 14: "Miracles and Christian Theism" by J. A. Cover Chapter 15: "Christianity and Ethics" by Frances Howard-Snyder Chapter 16: "The Authority of Scripture" by Douglas Blount. (shrink)

This essay frames systemic patterns of mental abuse against women of color and Indigenous women on Turtle Island (North America) in terms of larger design-of-distribution strategies in settler colonial societies, as these societies use various forms of social power to distribute, reproduce, and automate social inequalities (including public health precarities and mortality disadvantages) that skew socio-economic gain continuously toward white settler populations and their descendants. It departs from traditional studies in gender-based violence research that frame mental abuses such as gaslighting--commonly (...) understood as mental manipulation through lying or deceit--stochastically, as chance-driven interpersonal phenomena. Building on structural analyses of knowledge in political epistemology (Dotson 2012, Berenstain 2016), political theory (Davis and Ernst 2017), and Indigenous social theory (Tuck and Yang 2012), I develop the notion of cultural gaslighting to refer to the social and historical infrastructural support mechanisms that disproportionately produce abusive mental ambients in settler colonial cultures in order to further the ends of cultural genocide and dispossession. I conclude by proposing a social epidemiological account of gaslighting that a) highlights the public health harms of abusive ambients for minority populations, b) illuminates the hidden rules of social structure in settler colonial societies, and c) amplifies the corresponding need for structural reparations. (shrink)

RESUMO A inseminação artificial (IA) é a biotecnologia mais empregada com vantagens superiores em relação a utilização da monta natural, cuja eficácia se dá na larga escala de reprodução entre os bovinos. Associando essa biotécnica com hormônios pode-se estabelecer manipulações do sistema reprodutivo da fêmea, levando a manejos de inúmeras cabeças de gado para inseminar a um tempo fixo. Portanto, foram realizados 5 protocolos de IATF, tendo 2 categorias de animais: nulíparas e multíparas. No protocolo 1 foram submetidas 81 multíparas, (...) resultando em 47 animais prenhes; No protocolo 2 foram protocoladas 103 animais multíparas, no qual resultou em 51 prenhes; já o protocolo 5 foram submetidas 77 animais multíparas, no qual resultou em 36 animais prenhes. Cada serviço realizado foi matematicamente calculado, sendo o ponto de partida o escore corporal, bem estar animal e a técnica bem exercida. Desta forma obteve bons resultados na (IATF) , no qual destaca-se o percentual : o protocolo 1 obteve 58,02%, o protocolo 2 obteve 49,51% na taxa de prenhez, No protocolo 3 obteve 55,67% na taxa de prenhez, o protocolo 4 obteve 53,33% de prenhes, já o protocolo 5 resultou em 46,75% de prenhez. O uso das biotecnologias da reprodução, realizadas em bovinos de corte, obteve resultado dentro do descrito pela literatura consultada. A boa taxa de prenhes apresentada na IATF deveu-se ao bom controle hormonal do ciclo estral e da qualidade do sêmen utilizado. A taxa de prenhez dos animais que foram submetidos à monta natural foi baixa pelo fato de que os reprodutores não conseguiram cobrir todas as fêmeas. ABSTRACT The artificial insemination (AI) is the most used biotechnology with superior advantages in relation to the use of natural mounting, whose effectiveness is given in the large scale of reproduction among cattle. Associating this biotechnique with hormones it is possible to establish manipulations of the reproductive system of the female, leading to managements of numerous heads of cattle to inseminate at a fixed time. Therefore, 5 IATF protocols were performed, having 2 categories of animals: nulliparous and multiparous. In protocol 1, 81 multiparous animals were submitted, resulting in 47 pregnant animals; in protocol 2, 103 multiparous animals were submitted, resulting in 51 pregnancies; and in protocol 5, 77 multiparous animals were submitted, resulting in 36 pregnant animals. Each service performed was mathematically calculated, with the starting point being the body score, animal welfare and the well exercised technique. Thus obtained good results in the (IATF), which highlights the percentage: protocol 1 obtained 58.02%, protocol 2 obtained 49.51% in pregnancy rate, in protocol 3 obtained 55.67% in pregnancy rate, protocol 4 obtained 53.33% pregnant, and protocol 5 resulted in 46.75% pregnant. The use of the reproduction biotechnologies, performed in beef cattle, obtained results within the described by the consulted literature. The good pregnancy rate presented in the IATF was due to the good hormonal control of the estrous cycle and the quality of the semen used. The pregnancy rate of animals that were subjected to natural mating was low due to the fact that the sires could not cover all the females. Keywords: Hormones. Cattle Pregnancy Rate. Artificial Insemination in Cattle. Hormones in Cattle Reproduction. -/- REFERÊNCIAS BIBLIOGRÁFICAS AMBRÓSIO, P. H. et al. Ressincronização da ovulação em programas de IATF: novas estratégias. 2018. BARUSELLI, P. S.; GIMENES, L. U.; SALES, J. N. de S. Fisiologia reprodutiva de fêmeas taurinas e zebuínas. Revista Brasileira de Reprodução Animal, v. 31, n. 2, p. 205-211, 2007. BARUSELLI, P. S. et al. Evolução e perspectivas da inseminação artificial em bovinos. Revista Brasileira de Reprodução Animal, v. 43, n. 2, p. 308-314, 2019. BÓ, G. A. et al. Alternative programs for synchronizing and resynchronizing ovulation in beef cattle. Theriogenology, v. 86, n. 1, p. 388-396, 2016. BOTTINO, M. P. et al. Effects of eCG and FSH in timed artificial insemination treatment regimens on estrous expression and pregnancy rates in primiparous and multiparous Bos indicus cows. Animal Reproduction Science, v. 228, p. 106751, 2021. DA SILVA, Emanuel Isaque Cordeiro. Técnica da Inseminação Artificial em Bovinos: Manejo Passo a Passo. 2020. DA SILVA, Emanuel Isaque Cordeiro. Reprodução Animal: Inseminação Artificial. 2020. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia da Reprodução Animal: Ovulação, Controle e Sincronização do Cio. 2020. DA SILVA, Emanuel Isaque Cordeiro. Fisiologia da Reprodução de Bovinos Leiteiros: Aspectos Básicos e Clínicos. Emanuel Isaque Cordeiro da Silva, 2022. KRAUS, Beth M.; PARENTE, Eric J.; TULLENERS, Eric P. Laryngoplasty with ventriculectomy or ventriculocordectomy in 104 draft horses (1992–2000). Veterinary Surgery, v. 32, n. 6, p. 530-538, 2003. MONGELLI, Melissa Sanches; TAVARES, Izabel Cristina; FERRANTE, Marcos. Evolução e premissas dos protocolos hormonais de inseminação artificial em tempo fixo na pecuária. Ciência Animal, v. 31, n. 1, p. 119-133, 2021. VILELA, G. C. Protocolos de IATF em novilhas precoce e super precoce. 2021. (shrink)

Emphasizing the human body in all of its forms, Beauty Unlimited expands the boundaries of what is meant by beauty both geographically and aesthetically. Peg Zeglin Brand and an international group of contributors interrogate the body and the meaning of physical beauty in this multidisciplinary volume. This striking and provocative book explores the history of bodily beautification; the physicality of socially or culturally determined choices of beautification; the interplay of gender, race, class, age, sexuality, and ethnicity within and on the (...) body; and the aesthetic meaning of the concept of beauty in an increasingly globalized world. Foreward by Carolyn Korsmeyer. Authors include Noel Carroll, Gregory Velazco Y Trianosky, Monique Roelofs, Whitney Davis, Eleanor Heartney, Diana Tietjens Meyers, Phoebe M. Farris, Mary Devereaux, Jo Ellen Jacobs, Karina L. Cespedes-Cortes and Paul C. Taylor, Fedwa Malti-Douglas, Stephen Davies, Jane Duran, Valerie Sullivan Fuchs, Keith Lehrer, Allen Douglas, Cynthia Freeland, Eva Kit Wah Man, Mary Bittner Wiseman, and Peg Brand's essay, "ORLAN Revisited: Disembodied Virtual Hybrid Beauty.". (shrink)

PRINCÍPIOS DA DIGESTÃO DOS ALIMENTOS NOS BEZERROS -/- -/- E. I. C. da Silva -/- Departamento de Agropecuária – IFPE Campus Belo Jardim -/- Departamento de Zootecnia – UFRPE sede -/- -/- PRINCÍPIOS DA DIGESTÃO DOS ALIMENTOS NOS BEZERROS -/- -/- INTRODUÇÃO -/- Se todos os bezerros pudessem ser criados por suas mães, haveria pouca necessidade de inúmeros livros, artigos e trabalhos, como esse, sobre a criação e o manejo básico desses animais. A maioria das vacas desempenha um ótimo papel (...) na criação dos seus descendentes, desde que sejam tomados os devidos cuidados com relação a alimentação, saúde e a outros aspectos relativos à criação desses neonatos. A essência da pecuária bovina relativa à criação de bezerros é manter esses animais vivos e aptos o suficiente para desempenhar atividades produtivas de grande importância na propriedade. Para tanto, os criadores necessitam entender o desenvolvimento do trato digestivo do bezerro e os conceitos básicos da digestão dos alimentos por ele, e é isso que pretendo aclarar de forma clara e concisa com esse trabalho. -/- -/- 1.1 O TRATO DIGESTIVO DO BEZERRO -/- Um animal adulto necessita de quatro estômagos funcionais para dar-lhe a capacidade de utilizar a ampla gama de alimentos disponíveis. -/- O retículo e o rúmen abrigam milhões de micróbios que fermentam e digerem o material vegetal, em especial às presentes nas forragens. O omaso permite a absorção de água do conteúdo do intestino. O abomaso, ou quarto estômago, é o verdadeiro estômago, comparável ao dos humanos, e permite a digestão ácida dos alimentos. -/- O bezerro muito jovem não desenvolve a capacidade de digerir o pasto, sendo assim o abomaso é o único estômago funcional ao nascer. Tanto os animais recém-nascidos como os adultos têm um intestino delgado funcional que permite a digestão alcalina dos alimentos. -/- A figura 1 ilustra a anatomia dos estômagos e intestino delgado de um bezerro recém-nascido. Esse diagrama esquemático mostra as dimensões relativas dos quatro estômagos, o sulco esofágico, que vai do esôfago até o abomaso, e o esfíncter pilórico ou válvula no fundo do abomaso, que controla a velocidade de movimento do conteúdo do intestino no duodeno. -/- O omaso e o abomaso representam cerca de 70% da capacidade total do estômago no bezerro recém-nascido. Por outro lado, nas vacas adultas, eles compõem apenas 30% da capacidade total do estômago (figura 2). -/- A digestão dos alimentos é auxiliada pela secreção de certos produtos químicos denominados enzimas, que estão presentes nas várias partes do intestino. Por exemplo, os bezerros produzem a enzima renina na parede do abomasal para auxiliar na digestão das proteínas do leite, enquanto a lactase é produzida na parede do duodeno para a digestão do açúcar do leite (lactose). Estas enzimas operam mais eficazmente em diferentes níveis de acidez no conteúdo do intestino, ácido no abomaso e alcalino no duodeno. Para conseguir isso, o bezerro segrega eletrólitos, ou sais minerais, com as enzimas, para mudar o conteúdo do intestino de um tipo para outro. -/- Os produtos finais da digestão dos diferentes componentes dos alimentos são absorvidos através da parede do intestino, mediante as vilosidades intestinais, para a corrente sanguínea, onde são levados para as diferentes partes do corpo para o crescimento e desenvolvimento do animal. -/- -/- 1.2 O BEZERRO ALIMENTADO COM LEITE -/- O Leite ou substituto do leite, quer seja apreendido através de uma teta ou bebido de um balde, é canalizado do esôfago através do sulco esofágico para o abomaso. Este sulco é um pequeno canal na parede do rúmen que é controlado por músculos que permitem que os líquidos sejam diretamente enviados para o abomaso e que não entrem no rúmen. O sulco é ativado em resposta a diferentes estímulos. Funciona bem quando os bezerros amamentam-se através das tetas das mães, mas às vezes não funciona quando bebem de um balde. Essa parece ser uma condição psicológica em resposta aos bezerros separados de suas mães. A maioria dos bezerros podem ser treinados pelo tratador para beber o leite do balde rapidamente e bem, a metodologia empregada é a da persuasão do animal, ao qual o mesmo possa responder positivamente à nova rotina diária e à mãe substituta na forma do criador do bezerro. Quando o leite ou o substituto do leite entra no abomaso, forma um coágulo firme dentro de alguns minutos sob a influência das enzimas renina e pepsina. Este é o mesmo processo envolvido na fabricação de queijo ou junket, usando renina para coagular a proteína do leite. A coagulação do leite retarda a taxa em que flui para fora do abomaso, permitindo assim uma liberação constante de nutrientes alimentares em todo o intestino e, eventualmente, para a corrente sanguínea. Pode levar de 12 a 18 horas para que a coalhada de leite seja totalmente digerida. -/- As enzimas que atuam nas proteínas do leite requerem um ambiente ácido e esse é fornecido pela secreção do ácido clorídrico no abomaso. No entanto, até que a digestão ácida esteja operando de forma eficiente, e isso pode levar até sete dias, a única forma de proteína que pode ser digerida é a caseína. Não há substituto para a caseína no bezerro muito jovem. Os substitutos do leite que contêm outras formas de proteína não podem ser devidamente digeridos até que os bezerros sejam mais velhos. Logo, é necessário muito cuidado para não fornecer substitutos ou sucedâneos que contenham fontes proteicas que não possam ser digeridas pelo estômago do animal, para que não ocasione complicações gastrintestinais. -/- A digestão do leite pode ser melhorada com a inclusão de coalho, que pode ser obtido a partir de fábricas de queijo ou aditivos comerciais de leite de bezerro para a primeira semana ou mais. Esses produtos comerciais podem fornecer ácidos adicionais para reduzir o pH abomasal e incrementar a quantidade de enzimas e bactérias específicas para aumentar a taxa de degradação da coalhada de leite. Tais aditivos são chamados probióticos, na medida em que ajudam nos processos digestivos normais. A pesquisa nem sempre os encontrou para melhorar o desempenho e a saúde dos bezerros, e eles são mais propensos a ser benéficos quando os bezerros estão sofrendo de problemas de saúde. Além disso, a sua eficácia, em termos de custo-benefício é, por vezes, questionada. -/- Qualquer leite de uma alimentação anterior está envolvido neste coágulo recém-formado. As proteínas líquidas de soro de leite e a lactose são rapidamente separadas da coalhada de leite e passam para o abomaso. A gordura do leite contida na coalhada de leite é decomposta por outra enzima, a lipase. Esta é secretado na boca pela saliva e incorporada quando o leite é engolido. A alimentação pelas tetas em vez da alimentação através do balde parece produzir mais saliva e, portanto, mais lipase. A digestão adicional da proteína do leite e da gordura ocorre no duodeno com a ajuda das enzimas produzidas no pâncreas. -/- A lactose, que é rapidamente liberada da coalhada de leite no abomaso, é dividida em glicose e galactose e estas são absorvidas na corrente sanguínea para formar a principal fonte de energia para os bezerros jovens. -/- As gorduras são divididas em ácidos graxos e glicerol para absorção e uso como energia, enquanto as proteínas são divididas em aminoácidos e peptídeos para absorção e uso como fontes de proteína corporal. -/- O amido de cereais, por exemplo, é uma importante fonte de energia em bezerros mais velhos, mas esses animais, nas suas primeiras semanas de vida, não conseguem digerir o amido. -/- O abomaso não é ácido até que o bezerro tenha 1-2 dias de idade e isso apresenta vantagens e desvantagens. A principal vantagem é que as proteínas imunes no colostro não podem ser digeridas nesse compartimento estomacal, por isso são absorvidas na corrente sanguínea na mesma forma quando produzidas pela vaca. Isso garante o seu papel como anticorpos para proteger contra as doenças e infecções. A baixa acidez do conteúdo abomasal no bezerro recém-nascido constitui um risco potencial das bactérias (e provavelmente vírus) tomadas através da boca. Estes não serão mortos pela digestão ácida, sendo assim podem passar para os intestinos, onde podem fazer mal ao bezerro recém-nascido. -/- Todos os bezerros pegam bactérias nos primeiros dias de vida e isso é essencial para o desenvolvimento normal do rúmen (flora microbiana). No entanto, a primeira bactéria a colonizar o intestino também pode causar danos. Desde que o bezerro tenha bebido colostro, os anticorpos maternos podem controlar a propagação dessas bactérias mais nocivas. -/- O bezerro alimentado com leite deve, então, produzir uma digestão ácida no abomaso e uma digestão alcalina no duodeno. Isto é conseguido pela produção de eletrólitos na parede do intestino. -/- Bezerros que sofrem de escoriações devido a distúrbios nutricionais ou infecções bacterianas podem perder grandes quantidades de água e eletrólitos em suas fezes. Estes devem ser reabastecidos como parte do tratamento para as escoriações. -/- O colostro é o primeiro leite produzido por vacas recém-paridas. Além de fornecer nutrientes essenciais para a alimentação animal, fornece anticorpos maternos que permitem a transferência passiva de imunidade contra doenças. As recomendações para a alimentação com colostro serão abordadas brevemente em outro trabalho. -/- -/- 1.3 DESENVOLVIMENTO DO RÚMEN E O PROCESSO DE DESMAME -/- Quando os bezerros são desmamados, o custo da criação diminui acentuadamente. Os custos de alimentação são mais baixos, os insumos de trabalho são reduzidos e a incidência de problemas de saúde é menor. No sentido econômico, faz sentido desmamar os bezerros assim que for razoável. No entanto, o bezerro é forçado a sofrer várias mudanças dramáticas, a saber: -/-  A fonte primária de nutrientes muda de líquido para sólido. -/-  A quantidade de matéria seca que o bezerro recebe é reduzida. -/-  O bezerro deve adaptar-se de um tipo monogástrico a um ruminante de digestão, que inclui a fermentação de alimentos. -/-  Mudanças na habitação e no manejo muitas vezes ocorrem em torno do desmame, o que pode aumentar o estresse. -/- Ao nascer, o rúmen é uma parte pequena e estéril do intestino que, ao desmame deve se tornar o compartimento mais importante dos quatro estômagos. Deve aumentar em tamanho, atividade metabólica interna e fluxo sanguíneo externo. Os cinco requisitos para o desenvolvimento ruminal são: -/-  Estabelecimento de bactérias. -/-  Líquido. -/-  Saída de material (ação muscular). -/-  Capacidade absortiva do tecido. -/-  Substrato para permitir o crescimento bacteriano, tais como minerais reciclados, bem como nutrientes para alimentação. -/- Antes do consumo de alimentos sólidos, as bactérias existentes fermentam o cabelo ingerido, o estrato e o leite que flui do abomaso para o rúmen. A maior parte da água que entra no rúmen provém da água livre (água real não contida no leite ou na solução substituta do leite). O leite contornará o rúmen através do sulco esofágico, enquanto a água livre não. -/- O rúmen se desenvolve a partir de um órgão muito pequeno em bezerros recém-nascidos (1-2 L) para a parte mais importante do intestino (25-30 L) por 3 meses de idade. Ele pode aumentar muito rapidamente durante as primeiras semanas de vida, dado o manejo da alimentação direita. -/- O crescimento do rúmen ocorre apenas sob a influência dos produtos finais da digestão no mesmo, que resultam da fermentação de alimentos sólidos pelos micróbios presentes nesse compartimento. O desenvolvimento ocorre em grande parte através do crescimento das papilas ruminais (figura 5 e 6) na parede ruminal (estruturas semelhantes a folhas na superfície interna), que aumentam a área superficial do rúmen e, portanto, a sua capacidade de absorver estes produtos finais de digestão. Portanto, os concentrados favorecem melhor o desenvolvimento dessas papilas ruminais. Para tanto, é necessário, com um tempo, ir incrementando a dieta sólida gradativamente para que esses animais deixem de consumir o leite das vacas produtoras e possam alimentar-se de ração e pastagens, que é a finalidade da criação de bovinos, ou seja, criar animais com menor custo possível e engordá-los através de ração, mas principalmente de pastagens. -/- A capacidade do rúmen e a ingestão de alimentos sólidos estão intimamente relacionadas. O desenvolvimento do rúmen é muito lento em bezerros alimentados com grandes quantidades de leite. O leite satisfaz seus apetites para que eles não tenham fome suficiente para comer qualquer alimento sólido. Logo, é necessário diminuir paulatinamente o fornecedor do leite para esses animais, favorecendo a ingestão de alimentos sólidos e desenvolvendo o rúmen, estômago que digere as fibras das forragens e que os tona animais peculiares. -/- A ruminação pode ocorrer com cerca de 2 semanas de idade e é uma boa indicação de que o rúmen está se desenvolvendo. Alimentos sólidos, bem como a ruminação, estimulam a produção de saliva e isso fornece nutrientes como ureia e bicarbonato de sódio para produzir os substratos para o crescimento e desenvolvimento da flora bacteriana. -/- No desmame precoce, é importante limitar a quantidade de leite oferecida e a sua disponibilidade durante todo o dia. Também é essencial fornecer alimentos sólidos. Os grosseiros (de baixa ou alta qualidade) devem ser oferecidos em combinação com concentrados de alta qualidade. -/- O criador deve tomar cuidado com o fornecimento de alimentos como a ração farelada, uma vez que essa ração pode entrar pelas vias nasais e ocasionar complicações respiratórias; há alguns relatos de bezerros mortos após a ingestão de ração farelada, na autópsia de um dos casos foi diagnosticada uma morte por esses grãos farelados presentes no pulmão. Portanto, para evitar complicações o ideal é que se forneça uma ração denominada peletizada. -/- Os alimentos grosseiros (volumosos) estimulam o desenvolvimento do rúmen, enquanto os concentrados fornecem nutrientes para a alimentação animal que não são fornecidos pelas quantidades limitadas de leite oferecidas. Sem os concentrados, o crescimento dos bezerros é lento, mas o rúmen ainda se desenvolve, resultando em animais barrigudos. -/- A ureia fornece nitrogênio para os micróbios, enquanto o bicarbonato de sódio atua como um tampão ruminal, ajudando a manter um pH estável no conteúdo do rúmen. Isso é, particularmente, importante quando os bezerros comem grandes quantidades de grãos de cereais na vida adulta, pois os micróbios do rúmen podem produzir muito ácido lático durante a fermentação desse material. -/- Envenenamento por grãos ou acidose ocorre quando os níveis de ácido lático são excessivamente elevados e tornam-se tóxicos para os micróbios do rúmen e, eventualmente, para o animal. Assim como os produtos finais que são absorvidos através da parede do rúmen, a fermentação microbiana produz os gases dióxido de carbono e metano e estes são normalmente exalados. Quando algo impede a fuga destes gases do rúmen, o inchaço pode se manifestar em qualquer fase da vida, diz-se do animal estufado. -/- -/- 1.4 O PAPEL DA FORRAGEM NO PROCESSO DE DESMAME -/- Existem inúmeras controvérsias acerca do papel da forragem no processo de desmame. Pesquisas realizadas na década de 1980 indicaram claramente que a forragem era benéfica, enquanto pesquisas da década de 1990 descobriram que nem sempre era necessário o fornecimento da forragem para que os bezerros fossem desmamados e que não sofresse estresse e nem apresentasse baixa eficiência produtiva e reprodutiva no futuro. Na maioria das pesquisas anteriores, os bezerros eram desmamados com a oferta de concentrados moídos como pellets com ou sem a presença de feno longo ou palha. Porém, a inclusão de forragens na dieta melhorou a ingestão e o desempenho, além de permitir o desmame precoce. -/- Na pesquisa posterior, os bezerros geralmente alimentavam-se de concentrados grosseiramente moídos, além de alguns volumosos, enquanto alguns até incluíam volumosos picados finos na mistura (às vezes chamados de mistura muesli por apresentar o capim e a ração). Nesses estudos, verificou-se que a inclusão de feno ou palha adicional teve pouco efeito no desempenho pré-desmame. -/- Os sistemas de criação de bezerros australianos frequentemente diferem dos demais, especialmente em áreas de parto sazonais. Um número excessivo elevado de bezerros precisam ser criados de uma só vez para lhes fornecer, a todos, currais individuais durante todo o seu período de amamentação. Consequentemente, os bezerros são criados em grupos. Além disso, os ingredientes da maioria dos concentrados para esses animais são finamente moídos. Nessas situações, descobriu-se que a palha limpa é um alimento útil e que deve ser incluso no período pré-desmame. Alguns agricultores preferem feno de boa qualidade, porém estes agricultores geralmente têm bezerros em grupos muito pequenos, muitas vezes um ou dois, por isso possuem maior controle sobre a ingestão de forragem. -/- Figura 7: A alimentação volumosa de bezerros alimentados com leite é uma questão controversa. Imagem cedida pelo IPA -/- É difícil e, portanto, mais caro que os produtores de rações incorporem feno picado nas refeições dos bezerros. Os pellets são muito mais fáceis, pois eles vão fluir para silos. Por fim, os produtores de leite devem incluir o componente volumoso no regime alimentar pré-desmame. A pastagem não é a fonte ideal de forragem volumosa para os bezerros alimentados com leite, uma vez que possui muito pouca fibra e uma baixa densidade de energia alimentar. O seu elevado teor de água limita a sua capacidade de fornecer energia alimentar adequada aos animais em crescimento. Para ingerir a pastagem a capacidade ruminal deveria ser maior, bezerros jovens simplesmente não conseguem comer pasto suficiente, a menos que seja de alta em qualidade. -/- Os bezerros criados com leite e fornecimento gradual de concentrados apresentam uma boa função ruminal às 3 semanas de vida, além de possuírem uma suficiente capacidade ruminal para o desmame entre às 4-6 semanas de idade. No entanto, se a dieta for baseada em leite restrito e pastagem de alta qualidade, a capacidade do rúmen pode não ser suficiente para o desmame até às 8-10 semanas de vida. Mesmo assim, as taxas de crescimento seriam menores em bezerros desmamados com base alimentar somente à pasto, uma vez que a ingestão de energia é insuficiente devido às limitações físicas da capacidade ruminal. -/- Se a qualidade for muito boa e produza apetite, os bezerros preferem volumosos ao invés do concentrado, o que leva a uma ingestão reduzida de nutrientes durante alimentação, tendo como efeito um crescimento mais lento. Quando volumosos e concentrados fornecem apetite no animal, juntamente com o leite limitado, os bezerros podem comer cerca de 10% de palha e 90% de concentrados. Sem o volumoso e a ruminação resultante, o desenvolvimento do rúmen será mais lento devido à falta de saliva e produtos finais da digestão de fibras presentes na parede celular das forragens. -/- -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- -/- BEN ASHER, Aharon. Manual de cría de becerras. Zaragoza: Acribia, 1999. -/- BITTAR, Carla Maris Machado; PORTAL, Rafaela Nunes Sanchez; PEREIRA, Anna Carolina Fett da Cunha. Criação de bezerras leiteiras. Piracicaba: EDUSP, 2018. -/- BLUM, J. W. Nutritional physiology of neonatal calves. Journal of animal physiology and animal nutrition, v. 90, n. 1‐2, p. 1-11, 2006. -/- CAMPOS, OF de. Criação de bezerros até a desmama. Coronel Pacheco: EMBRAPA/CNPGL, 1985. -/- COELHO, S. G. Criação de bezerros. II Simpósio Mineiro de Buiatria, Anais., Belo Horizonte, 2005. -/- DAVIS, Carl L. et al. The development, nutrition, and management of the young calf. Iowa State University Press, 1998. -/- DE OLIVEIRA, Juliana Silva; DE MOURA ZANINE, Anderson; SANTOS, Edson Mauro. Fisiologia, manejo e alimentação de bezerros de corte. Arquivos de Ciências Veterinárias e Zoologia da UNIPAR, v. 10, n. 1, 2007. -/- DRACKLEY, James K. Calf nutrition from birth to breeding. Veterinary Clinics of North America: Food Animal Practice, v. 24, n. 1, p. 55-86, 2008. -/- FERREIRA, Lucas Silveira et al. Desempenho animal e desenvolvimento do rúmen de bezerros leiteiros aleitados com leite integral ou sucedâneo. Boletim de Indústria Animal, v. 65, n. 4, p. 337-345, 2008. -/- GUILLOTEAU, P.; ZABIELSKI, R.; BLUM, J. W. Gastrointestinal tract and digestion in the young ruminant: ontogenesis, adaptations, consequences and manipulations. J Physiol Pharmacol, v. 60, n. Suppl 1, p. 37-46, 2009. -/- HUBER, J. T. Development of the digestive and metabolic apparatus of the calf. Journal of Dairy Science, v. 52, n. 8, p. 1303-1315, 1969. -/- LONGENBACH, J. I.; HEINRICHS, Arlyn Judson. A review of the importance and physiological role of curd formation in the abomasum of young calves. Animal feed science and technology, v. 73, n. 1-2, p. 85-97, 1998. -/- LOPES, Marcos Aurélio; VIEIRA, P. de F. Criação de bezerros leiteiros. Jaboticabal: Funep, 1998. -/- LUCCI, Carlos de Sousa. Bovinos leiteiros jovens: nutrição, manejo, doenças. São Paulo: Nobel, 1989. -/- ROY, James Henry Barstow et al. The calf. Boston: Butterworths., 1980. -/- SAVAGE, E. S.; MCCAY, C. M. The nutrition of calves; A review. Journal of Dairy Science, v. 25, n. 7, p. 595-650, 1942. -/- THIVEND, P.; TOULLEC, R.; GUILLOTEAU, P. Digestive adaptation in the preruminant. In: Digestive physiology and metabolism in ruminants. Springer, Dordrecht, 1980. p. 561-585. (shrink)

The file on this site provides the slides for a lecture given in Hangzhou in May 2018, and the lecture itself is available at the URL beginning 'sms' in the set of links provided in connection with this item. -/- It is commonly assumed that regular physics underpins biology. Here it is proposed, in a synthesis of ideas by various authors, that in reality structures and mechanisms of a biological character underpin the world studied by physicists, in principle supplying detail (...) in the domain that according to regular physics is of an indeterminate character. In regular physics mathematical equations are primary, but this constraint leads to problems with reconciling theory and reality. Biology on the other hand typically does not characterise nature in quantitative terms, instead investigating in detail important complex interrelationships between parts, leading to an understanding of the systems concerned that is in some respects beyond that which prevails in regular physics. It makes contact with quantum physics in various ways, for example in that both involve interactions between observer and observed, an insight that explains what is special about processes involving observation, justifying in the quantum physics context the replacement of the unphysical many-worlds picture by one involving collapse. The link with biology furthermore clarifies Wheeler’s suggestion that a multiplicity of observations can lead to the ‘fabrication of form’, including the insight that this process depends on very specific ‘structures with power’ related to the 'semiotic scaffolding' of the application of sign theory to biology known as biosemiotics. -/- The observer-observed 'circle' of Wheeler and Yardley is a special case of a more general phenomenon, oppositional dynamics, related to the 'intra-action' of Barad's Agential Realism, involving cooperating systems such as mind and matter, abstract and concrete, observer and observed, that preserve their identities while interacting with one another in such a way as to act as a unit. A third system may also be involved, the mediating system of Peirce linking the two together. Such a situation of changing connections and separations may plausibly lead in the future to an understanding of how complex systems are able to evolve to produce 'life, the universe and everything'. -/- (Added 1 July 2018) The general structure proposed here as an alternative to a mathematics-based physics can be usefully characterised by relating it to different disciplines and the specialised concepts utilised therein. In theoretical physics, the test for the correctness of a theory typically involves numerical predictions, corresponding to which theories are expressed in terms of equations, that is to say assertions that two quantities have identical values. Equations have a lesser significance in biology which typically talks in terms of functional mechanisms, dependent for example on details of chemistry and concepts such as genes, natural selection, signals and geometrical or topologically motivated concepts such as the interconnections between systems and the unfolding of DNA. Biosemiotics adds to this the concept of signs and their interpretation, implying novel concepts such as semiotic scaffolding and the semiosphere, code duality, and appreciation of the different types of signs, including symbols and their capacity for abstraction and use in language systems. Circular Theory adds to this picture, as do the ideas of Barad, considerations such as the idea of oppositional dynamics. The proposals in this lecture can be regarded as the idea that concepts such as those deriving from biosemiotics have more general applicability than just conventional biology and may apply, in some circumstances, to nonlinear systems generally, including the domain new to science hypothesised to underlie the phenomena of present-day physics. -/- The task then has to be to restore the mathematical aspect presumed, in this picture, not to be fundamental as it is in conventional theory. Deacon has invoked a complex sequence of evolutionary steps to account for the emergence over time of human language systems, and correspondingly mathematical behaviour can be subsumed under the general evolutionary mechanisms of biosemiotics (cf. also the proposals of Davis and Hersh regarding the nature of mathematics), so that the mathematical behaviour of physical systems is consistent with the proposed scheme. In conclusion, it is suggested that theoretical physicists should cease expecting to find some universal mathematical ‘theory of everything’, and focus instead on understanding in more detail complex systems exhibiting behaviour of a biological character, extending existing understanding. This may in time provide a more fruitful understanding of the natural world than does the regular approach. The essential concepts have an observational basis from both biology and the little-known discipline of cymatics (a discipline concerned with the remarkable patterns that specific waveforms can give rise to), while again computer simulations also offer promise in providing insight into the complex behaviours involved in the above proposals. -/- References -/- Jesper Hoffmeyer, Semiotic Scaffolding of Living Systems. Commens, a Digital Companion to C. S. Peirce (on Commens web site). Terrence Deacon, The Symbolic Species, W.W. Norton & Co. Karen Barad, Meeting the Universe Halfway: Quantum Physics and the Entanglement of Matter and Meaning, Duke University Press. Philip Davis and Reuben Hersh, The Mathematical Experience, Penguin. Ilexa Yardley, Circular Theory. (shrink)

There can be no doubt that Kant thought we should be reflective: we ought to care to make up our own minds about how things are and what is worth doing. Philosophical objections to the Kantian reflective ideal have centred on concerns about the excessive control that the reflective person is supposed to exert over her own mental life, and Kantians who feel the force of these objections have recently drawn attention to Kant’s conception of moral virtue as it is (...) developed in his later work, chiefly the Metaphysics of Morals. Melissa Merritt’s book is a distinctive contribution to this recent turn to virtue in Kant scholarship. Merritt argues that we need a clearer, and textually more comprehensive, account of what reflection is, in order not only to understand Kant’s account of virtue, but also to appreciate how it effectively rebuts long-standing objections to the Kantian reflective ideal. (shrink)

A common view among nontheists combines the de jure objection that theism is epistemically unacceptable with agnosticism about the de facto objection that theism is false. Following Plantinga, we can call this a “proper” de jure objection—a de jure objection that does not depend on any de facto objection. In his Warranted Christian Belief, Plantinga has produced a general argument against all proper de jure objections. Here I first show that this argument is logically fallacious (it makes subtle probabilistic fallacies (...) disguised by scope ambiguities), and proceed to lay the groundwork for the construction of actual proper de jure objections. (shrink)

Grete Hermann’s essay “Die naturphilosophischen Grundlagen der Quantenmechanik” has received much deserved scholarly attention in recent years. In this paper, I follow the lead of Elise Crull who sees in Hermann’s work the general outlines of a neo-Kantian interpretation of quantum theory. In full support of this view, I focus on Hermann’s central claim that limited spatio-temporal, and even analogically causal, representations of events exist within an overall relational structure of entangled quantum mechanical states that defy any unified spatio-temporal description. (...) In my view, Hermann also advances an important transcendental argument that perspectival spatio-temporal representations of nature have their foundations in general relational networks that are not spatio-temporal. The key point is that the adoption of a perspectival system within the general network induces the representation but only for that context. These ideas are consistent with a perspectival subject–object principle in Kant and also with Weyl’s work on Lie groups and their representations. (shrink)

In this paper, multi attribute decision making problem based on grey relational analysis in neutrosophic cubic set environment is investigated. In the decision making situation, the attribute weights are considered as single valued neutrosophic sets. The neutrosophic weights are converted into crisp weights. Both positve and negative GRA coefficients, and weighted GRA coefficients are determined. Hamming distances for weighted GRA coefficients and standard (ideal) GRA coefficients are determined. The relative closeness coefficients are derived in order to rank the alternatives. The (...) relative closeness coefficients are designed in ascending order. Finally, a numerical example is solved to demonstrate the applicability of the proposed approach. (shrink)

In this article I argue that the value of epistemic justification cannot be adequately explained as being instrumental to truth. I intend to show that false belief, which is no means to truth, can nevertheless still be of epistemic value. This in turn will make a good prima facie case that justification is valuable for its own sake. If this is right, we will have also found reason to think that truth value monism is false: assuming that true belief does (...) have value, there is more of final epistemic value than mere true belief. (shrink)

There is a basic distinction, in the realm of spatial boundaries, between bona fide boundaries on the one hand, and fiat boundaries on the other. The former are just the physical boundaries of old. The latter are exemplified especially by boundaries induced through human demarcation, for example in the geographic domain. The classical problems connected with the notions of adjacency, contact, separation and division can be resolved in an intuitive way by recognizing this two-sorted ontology of boundaries. Bona fide boundaries (...) yield a notion of contact that is effectively modeled by classical topology; the analogue of contact involving fiat boundaries calls, however, for a different account, based on the intuition that fiat boundaries do not support the open/closed distinction on which classical topology is based. In the presence of this two-sorted ontology it then transpires that mereotopology—topology erected on a mereological basis—is more than a trivial formal variant of classical point-set topology. (shrink)

For Kant, ‘reflection’ is a technical term with a range of senses. I focus here on the senses of reflection that come to light in Kant's account of logic, and then bring the results to bear on the distinction between ‘logical’ and ‘transcendental’ reflection that surfaces in the Amphiboly chapter of the Critique of Pure Reason. Although recent commentary has followed similar cues, I suggest that it labours under a blind spot, as it neglects Kant's distinction between ‘pure’ and ‘applied’ (...) general logic. The foundational text of existing interpretations is a passage in Logik Jäsche that appears to attribute to Kant the view that reflection is a mental operation involved in the generation of concepts from non-conceptual materials. I argue against the received view by attending to Kant's division between ‘pure’ and ‘applied’ general logic, identifying senses of reflection proper to each, and showing that none accords well with the received view. Finally, to take account of Kant's notio.. (shrink)

Various prominent theories of pain assume that it is pain’s biological function to inform organisms about damage to their bodies. I argue that this is a mistake. First, there is no biological evidence to support the notion that pain was originally selected for its informative capacities, nor that it currently contributes to the fitness of organisms in this specific capacity. Second, neurological evidence indicates that modulating mechanisms in the nociceptive system systematically prevent pain from serving a primarily informative role. These (...) considerations threaten to undermine standard perceptual and representational accounts of pain. (shrink)

The standard treatment of conditional probability leaves conditional probability undefined when the conditioning proposition has zero probability. Nonetheless, some find the option of extending the scope of conditional probability to include zero-probability conditions attractive or even compelling. This article reviews some of the pitfalls associated with this move, and concludes that, for the most part, probabilities conditional on zero-probability propositions are more trouble than they are worth.

I argue that the conjunction of perdurantism (the view that objects are temporally extended) and universalism (the thesis that any old class of things has a mereological fusion) gives rise to undesired complications when combined with certain plausible assumptions concerning the semantics of tensed statements.

Literature in epistemology tends to suppose that there are three main types of understanding – propositional, atomistic, and objectual. By showing that all apparent instances of propositional understanding can be more plausibly explained as featuring one of several other epistemic states, this paper argues that talk of propositional understanding is unhelpful and misleading. The upshot is that epistemologists can do without the notion of propositional understanding.

Much of the intuitive appeal of evidentialism results from conflating two importantly different conceptions of evidence. This is most clear in the case of perceptual justification, where experience is able to provide evidence in one sense of the term, although not in the sense that the evidentialist requires. I argue this, in part, by relying on a reading of the Sellarsian dilemma that differs from the version standardly encountered in contemporary epistemology, one that is aimed initially at the epistemology of (...) introspection but which generalizes to theories of perceptual justification as well. (shrink)

While theories of animal rights maintain that nonhuman animals possess prima facie rights, such as the right to life, the dominant philosophies of animal rights permit the killing of nonhuman animals for reasons of self-defense. I argue that the animal rights discourse on defensive killing is problematic because it seems to entail that any nonhuman animal who poses a threat to human beings can be justifiably harmed without question. To avoid this human-privileged conclusion, I argue that the animal rights position (...) needs to both (1) deploy a new criterion of liability to defensive harm, and (2) seriously consider whether human beings themselves are liable to defensive harm in human-animal conflicts. By shifting the focus to whether humans are liable to defensive harm, we will find that in many situations of human-animal conflict, human beings are actually the ones liable to be harmed because they are often culpable or, to some degree, morally responsible for posing an unjust threat to nonhuman animals. (shrink)

In this paper I argue that composer John Cage’s so-called ‘silent piece’, 4’33”, is music. I first defend it against the charge that it does not involve the organization of sound, which has been taken to be a necessary feature of music. I then argue that 4’33” satisfies the only other condition that must be met for it to be music: it bears the right socio-historical connections to its predecessors within its tradition (Western art music). I argue further that one (...) cannot understand the organized sound condition and the socio-historical condition separately and that understanding their interaction has theoretical benefits—not least of which is providing a groundwork for a more culturally inclusive philosophy of music. Finally, I consider a number of outstanding questions concerning the content of the organized sound condition for Western art music in the wake of 4’33”. (shrink)

The concept of niche (setting, context, habitat, environment) has been little studied by ontologists, in spite of its wide application in a variety of disciplines from evolutionary biology to economics. What follows is a first formal theory of this concept, a theory of the relations between objects and their niches. The theory builds upon existing work on mereology, topology, and the theory of spatial location as tools of formal ontology. It will be illustrated above all by means of simple biological (...) examples, but the concept of niche should be understood as being, like concepts such as part, boundary, and location, a structural concept that is applicable in principle to a wide range of different domains. (shrink)

To what extent are cognitive capacities, especially perceptual capacities, informationally encapsulated and to what extent are they cognitively penetrable? And why does this matter? Two reasons we care about encapsulation/penetrability are: (a) encapsulation is sometimes held to be definitional of modularity, and (b) penetrability has epistemological implications independent of modularity. I argue that modularity does not require encapsulation; that modularity may have epistemological implications independently of encapsulation; and that the epistemological implications of the cognitive penetrability of perception are messier than (...) is sometimes thought. (shrink)

I examine Mach's influence on American philosophy from 1890-1910, on Carus, James, Peirce, the American Realists and J.B. Stallo. I also consider the question of whether Mach was a pragmatist in the sense of Peirce and James. I conclude that early pragmatism was a method-centric theory whereas Mach's empiricism prized agreement with experience and downplayed the significance of inductive-scientific methods in general as a guide to discovery.

Bertrand Russell in "My Philosophical Development" claimed he converted to neutral monism in 1919, in the essay "On Propositions." I question whether Russell was really a complete neutral monist in the style of Mach and James and conclude that he was not. Russell's lingering commitment to image propositions and a linguistic theory of meaning and truth and falsity separate him from the more naturalistic causal theory of knowledge and error one finds in James and Mach.

This paper offers a "tu quoque" defense of strong AI, based on the argument that phenomena of self-consciousness and intentionality are nothing but the "negative space" drawn around the concrete phenomena of brain states and causally connected utterances and objects. Any machine that was capable of concretely implementing the positive phenomena would automatically inherit the negative space around these that we call self-consciousness and intention. Because this paper was written for a literary audience, some examples from Greek tragedy, noir fiction, (...) science fiction and Dada are deployed to illustrate the view. (shrink)

There are conflicting intuitions concerning the status of a boundary separating two adjacent entities (or two parts of the same entity). The boundary cannot belong to both things, for adjacency excludes overlap; and it cannot belong to neither, for nothing lies between two adjacent things. Yet how can the dilemma be avoided without assigning the boundary to one thing or the other at random? Some philosophers regard this as a reductio of the very notion of a boundary, which should accordingly (...) be treated a mere façon de parler. In this paper I resist this temptation and examine some ways of taking the puzzle at face value within a realist perspective—treating boundaries as ontologically on a par with (albeit parasitic upon) extended parts. (shrink)

Human cognitive acts are directed towards objects extended in space of a wide range of different types. What follows is a new proposal for bringing order into this typological clutter. The theory of spatially extended objects should make room not only for the objects of physics but also for objects at higher levels, including the objects of geography and of related disciplines. It should leave room for different types of boundaries, including both the bona fide boundaries which we find in (...) the physical world and the fiat (or human-demarcation-induced) boundaries with which much of geography has to deal. Two distinct axiomatic theories of boundaries are accordingly presented, and the need for both is examined in some detail. The resultant dual framework is shown to have application above all for our understanding of issues involving contact, division, and separation, issues which have posed serious difficulties for the ontological theories of boundaries that have been proposed hitherto. (shrink)

Due to Gӧdel’s incompleteness results, the categoricity of a sufficiently rich mathematical theory and the semantic completeness of its underlying logic are two mutually exclusive ideals. For first- and second-order logics we obtain one of them with the cost of losing the other. In addition, in both these logics the rules of deduction for their quantifiers are non-categorical. In this paper I examine two recent arguments –Warren (2020), Murzi and Topey (2021)– for the idea that the natural deduction rules for (...) the first-order universal quantifier are categorical, i.e., they uniquely determine its semantic intended meaning. Both of them make use of McGee’s open-endedness requirement and the second one uses in addition Garson’s (2013) local models for defining the validity of these rules. I argue that the success of both these arguments is relative to their semantic or infinitary assumptions, which could be easily discharged if the introduction rule for the universal quantifier is taken to be an infinitary rule, i.e. non-compact. Consequently, I reconsider the use of the ω-rule and I show that the addition of the ω-rule to the standard formalizations of first-order logic is categorical. In addition, I argue that the open-endedness requirement does not make the first-order Peano Arithmetic categorical and I advance an argument for its categoricity based on the inferential conservativity requirement. (shrink)

Epistemic internalism, by stressing the indispensability of the subject’s perspective, strikes many as plausible at first blush. However, many people have tended to reject the position because certain kinds of beliefs have been thought to pose special problems for epistemic internalism. For example, internalists tend to hold that so long as a justifier is available to the subject either immediately or upon introspection, it can serve to justify beliefs. Many have thought it obvious that no such view can be correct, (...) as it has been alleged that internalism cannot account for the possibility of the justification of beliefs stored in memory. -/- My aim in this paper is to offer a response that explains how memory justification is possible in a way that is consistent with epistemic internalism and an awareness condition on justification. Specifically, I will explore the plausibility of various options open to internalists, including both foundationalist and non-foundationalist approaches to the structure of justification. I intend to show that despite other difficult challenges that epistemic internalism might face, memory belief poses no special problems that the resources of internalism cannot adequately address. (shrink)